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1

Stanley, P. "Host defence mechanisms of the upper respiratory tract." Thesis, Imperial College London, 1988. http://hdl.handle.net/10044/1/47263.

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2

Bello, Ortí Bernardo. "Haemophilus parasuis host-pathogen interactions in the respiratory tract." Doctoral thesis, Universitat Autònoma de Barcelona, 2015. http://hdl.handle.net/10803/312855.

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En el sector veterinario, la enfermedad de Glässer es un proceso patogénico frecuente que conduce a pérdidas económicas considerables. Esta enfermedad es causada por Haemophilus parasuis. Aunque se ha llevado a cabo un esfuerzo importante hacia la comprensión de los factores que intervienen en la evolución de la enfermedad, la falta de completa protección de las vacunas comerciales sugieren que debe dirigirse más trabajo hacia el estudio de este proceso patogénico. Para aumentar el conocimiento en patogénesis desarrollamos una serie de experimentos. Es bien sabido que existen diferentes cepas
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3

Spyer, Moira Jane. "Respiratory syncytial virus host cell receptor interactions." Thesis, University of Reading, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269926.

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4

Jahnes, Benjamin C. "Host-Microbial Symbiosis Within the Digestive Tract of Periplaneta americana." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1595510199092557.

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5

Almeida, Sónia T. "Dynamics of bacterial colonization in the upper respiratory tract of the adult host." Doctoral thesis, Universidade Nova de Lisboa, Instituto de Tecnologia Química e Biológica António Xavier, 2020. http://hdl.handle.net/10362/101972.

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"Bacterial infections caused by microorganisms such as, Streptococcus pneumoniae and Staphylococcus aureus are a main cause of morbidity and mortality worldwide, particularly among young children, the elderly, and the immunocompromised of all ages. However, disease is incidental, and the natural lifestyle of these bacteria is through asymptomatic colonization of the upper respiratory tract. (...)"<br>N/A
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6

Svensson, Lovisa. "Nitric oxide and bacteria-host interactions in Escherichia coli urinary tract infection." Doctoral thesis, Högskolan i Kalmar, Naturvetenskapliga institutionen, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-29096.

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7

Winkle, Sean M., Andrea L. Throop та Melissa M. Herbst-Kralovetz. "IL-36γ Augments Host Defense and Immune Responses in Human Female Reproductive Tract Epithelial Cells". FRONTIERS MEDIA SA, 2016. http://hdl.handle.net/10150/617371.

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IL-36 gamma is a proinflamatory cytokine which belongs to the IL-1 family of cytokines. It is expressed in the skin and by epithelial cells (ECs) lining lung and gut tissue. We used human 3-D organotypic cells, that recapitulate either in vivo human vaginal or cervical tissue, to explore the possible role of IL-36 gamma in host defense against pathogens in the human female reproductive tract (FRT). EC were exposed to compounds derived from virus or bacterial sources and induction and regulation of IL-36 gamma and its receptor was determined. Polyinosinic-polycytidylic acid (poly I:C), flagelli
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8

Barbour, Matthew A. "Intraspecific trait variation structures species-interaction networks : a case study with the host plant Salix hookeriana." Thesis, University of British Columbia, 2016. http://hdl.handle.net/2429/59147.

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The strength and organization of species interactions determine the structure and dynamics of ecological communities. However, interactions do not occur between species per se – interactions occur between individuals. A rising challenge for ecology is to understand how intraspecific trait variation scales up to affect community structure and dynamics. My dissertation research has taken an empirical approach to addressing this challenge. Specifically, I conducted common garden experiments with the host plant Salix hookeriana in multiple environments to study the contributions of host-plant gene
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9

Einarsson, Gisli Geir. "The effect of bacterial and host proteinases on defence molecules in the cystic fibrosis respiratory tract." Thesis, Queen's University Belfast, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.516939.

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10

Arko-Mensah, John. "Mycobacterial infection: Immune evasion, host susceptibility and immunological markers of diagnostic importance." Doctoral thesis, Stockholm University, Wenner-Gren Institute for Experimental Biology, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-8208.

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<p>IIn the first study, we investigated the functional implications of prolonged TLR signalling on IFN-γ mediated killing of mycobacteria by murine macrophages <i>in vitro</i>. TLR2, but not TLR4 ligation interfered with IFN-γ mediated killing of mycobacteria in macrophages. In terms of mechanisms, neither TNF nor nitric oxide (NO) production was significantly affected, and the refractoriness induced could be reversed with increasing amounts of IFN-γ In the second study, we aimed to identify immunological markers of diagnostic importance in both the respiratory tract and serum during pulmonary
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11

Duell, Benjamin Luke. "Investigation of Host-Pathogen Interactions and Interleukin-10 Induction Mediated by Uropathogenic Escherichia coli during Urinary Tract Infection." Thesis, Griffith University, 2014. http://hdl.handle.net/10072/366580.

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Urinary tract infections (UTI) are a major source of morbidity, affecting 50% of women at least once, and sometimes with recurrent episodes. These infections can be localised as cystitis or urethritis, and sometimes develop more severely as pyelonephritis or urosepsis. UTI also affects the elderly and catheterised patients in large numbers. The burden on the health care system arises from more than 8 million UTI-related consultations per year; with health care costs estimated in excess of $3.5 billion, in the USA alone. While UTI is caused by a range of different microbes, the predominant infe
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12

Poudel, Bikash. "Understanding Host Resistance and Pathogen Biology in the Wheat-Fusarium graminearum Pathosystem." Diss., North Dakota State University, 2020. https://hdl.handle.net/10365/31811.

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Fusarium head blight (FHB) is a major challenge in global wheat production. In the United States, the disease is predominantly caused by the fungus Fusarium graminearum. Utilization of FHB-resistant wheat cultivars integrated with other measures such as fungicide application is the most effective approach for the management of this disease. This study aimed to 1) identify novel quantitative trait loci (QTL) for resistance to FHB in a Brazilian spring wheat cultivar ‘Surpresa’ through bi-parental mapping, 2) detect QTL for FHB resistance in a global panel of 233 spring wheat accessions by genom
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13

Tsai, Hsin Yuan. "Genomic basis of growth traits and host resistance against sea lice (L. Salmonis) in Atlantic salmon (S. Salar)." Thesis, University of Edinburgh, 2017. http://hdl.handle.net/1842/28918.

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Background Atlantic salmon (Salmo Salar) is a key aquaculture species in several countries. Since its critical role in economic sector and scientific research, this species has been relatively extensively investigated, in comparison with other farmed and wild aquatic species. However, the genetic components associated with growth and fillet-related traits are lack consistency, and the issue of sea louse disease in both wild and famed salmon is still unsolved. Objectives Overall aim of this project was to understand the genetic basis of growth-related traits and host resistance to sea lice usin
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14

Vaughan, Andrew. "Host-commensal interactions in the human upper respiratory tract: the mucosal immune response to Neisseria lactamica and Neisseria meningitidis." Thesis, University of Bristol, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492620.

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The human upper respiratory tract is colonised by a diverse commensal flora that is tolerated by the host without inducing an aberrant inflammatory response. N. meningitidis is an opportunistic pathogen that asymptomatically colonises the nasopharyngeal epithelium of older children and adults, but infrequently causes invasive disease. N. lactamica is a closely related commensal that colonises the nasopharyngeal epithelium of young children without causing disease. Both species can colonise for prolonged periods without being cleared. We have Investigated the development of mucosal immunity to
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15

Zhang, Lu. "Establishment and Development of Antibiotic Resistant Bacteria in Host Gastrointestinal Tract—Food, Drug, or Are We Born with It?" The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1316186957.

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16

Dobrijevic, Dragana. "Functional analysis of the predicted surface proteome of Gram-positive bacteria from the human gastrointestinal tract. A high-throughput approach to identification of immune modulators." Thesis, Paris 11, 2013. http://www.theses.fr/2013PA112182.

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Il est maintenant bien établi que le microbiote du tractus digestif humain joue un rôle important dans la santé humaine. Pourtant, nous commençons à peine à comprendre les mécanismes moléculaires par lesquels les bactéries agissent sur les cellules hôtes, des connaissances qui pourraient fournir des nouvelles orientations dans le traitement et la prévention de maladies. Cette dernière décennie a vu un développement rapide des études du microbiote intestinal, et à présent des quantités importantes de données métagénomiques ainsi que des centaines de séquences génomiques de bactéries commensales
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17

Carossino, Mariano. "CELLULAR AND MOLECULAR BASIS OF EQUINE ARTERITIS VIRUS PERSISTENT INFECTION IN THE STALLION REPRODUCTIVE TRACT: CHARACTERIZATION OF LOCAL HOST-PATHOGEN INTERACTIONS MEDIATING LONG-TERM VIRAL PERSISTENCE." UKnowledge, 2018. https://uknowledge.uky.edu/gluck_etds/35.

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Equine arteritis virus (EAV) has a global impact on the equine industry being the causative agent of equine viral arteritis (EVA), a reproductive, respiratory, and systemic disease of equids. A distinctive feature of EAV infection is that it establishes long-term persistent infection in the reproductive tract of stallions and is continuously shed in the semen (carrier state). Recent studies showed that long-term persistence is associated with a specific allele of the CXCL16 gene (CXCL16S). However, the cellular and molecular mechanisms underlying the establishment and maintenance of persistent
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18

Nam, Bora. "EVOLUTION OF EQUINE ARTERITIS VIRUS DURING PERSISTENT INFECTION IN THE REPRODUCTIVE TRACT OF THE STALLION AND THE MALE DONKEY." UKnowledge, 2017. https://uknowledge.uky.edu/gluck_etds/34.

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Equine arteritis virus (EAV) establishes persistent infection in the stallion reproductive tract, and the carrier stallion continues to shed virus in semen for weeks to years or lifelong. The objective of this study was to elucidate the intra-host evolution of EAV during persistent infection in stallions. Seven EAV seronegative stallions were experimentally infected with EAV KY84 strain and followed for 726 days post-infection, and sequential clinical samples including semen were collected for virus isolation and next-generation sequencing (NGS). In addition, archived sequential semen samples
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19

Scott, Kelsey L. "Studies in the Management of Pythium Seed and Root Rot of Soybean: Efficacy of Fungicide Seed Treatments, Screening Germplasm for Resistance, and Comparison of Quantitative Disease Resistance Loci to Three Species of Pythium and Phytophthora sojae." The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1524147394255409.

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20

Edward, Grahame. "Development and use of an in vitro air-liquid interface model of the bovine respiratory tract and multifaceted proteomic approaches to investigate host-pathogen interactions of Mannheimia haemolytica." Thesis, University of Glasgow, 2016. http://theses.gla.ac.uk/7777/.

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In the present study, an air-liquid interface culture system was optimised for the use of bovine airway epithelial cells. This culture system has been adopted for other species, where a pseudostratified epithelium comprising multiple cell types and resembling the in vivo environment is produced. Several aspects of the epithelial culture process were optimised, including (i) the cell harvesting process and the expansion of cells in submerged culture, (ii) the substrate material used for air-liquid interface culture, the effects of collagen-coating of the substrate, and the substrate porosity, (
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21

Sequira, Saannya. "Structural studies of a novel adhesin involved in host-specific Lactobacillus reuteri biofilm formation in the vertebrate gastrointestinal tract, and, Purification method development for structural studies of WaaP : an essential gram-negative bacteria lipopolysaccharide kinase." Thesis, University of East Anglia, 2016. https://ueaeprints.uea.ac.uk/65623/.

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In vertebrates, strains of the gut symbiont, Lactobacillus reuteri, form biofilms on the proximal gastric stratified epithelium in a host-dependent manner. The gene for a novel serine-rich repeat (SRR) adhesin, conserved amongst rat and porcine L. reuteri, is essential for successful biofilm formation, suggesting initial adhesion to be the most crucial step for colonisation, and a possible driver of host-specificity. High resolution crystal structures of the partial binding regions (BR) of two SRR adhesins, BR55 and BR78, from porcine L. reuteri ATCC 53608 and rodent L. reuteri 100-23 strains,
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22

Tang, Chongfa. "The inflammatory response of primary epithelial cells of the female genital tract to Chlamydia trachomatis infection, and its exacerbation by type-I interferon." Electronic Thesis or Diss., Sorbonne université, 2022. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2022SORUS121.pdf.

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Chlamydia trachomatis est une bactérie intracellulaire obligatoire, qui se développe principalement dans cellules épithéliales des muqueuses du tractus génital. Asymptomatiques dans la plupart des cas, les infections par ce pathogène peuvent entrainer des inflammations pelviennes. L’inflammation peut elle-même engendrer des fibroses et mener à une infertilité tubaire chez les femmes. Il est important d’étudier la réponse des cellules épithéliales, qui constituent la première ligne de défense contre l’infection par C. trachomatis, pour mieux comprendre ses manifestations pathologiques dans le t
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23

Saillant, Vincent. "Comprendre le mécanisme du système senseur d’hème des bactéries pathogènes, une cible antibiotique innovante A novel Enterococcus faecalis heme transport regulator (FhtR) is a heme sensor in the gastrointestinal tract." Thesis, université Paris-Saclay, 2020. http://www.theses.fr/2020UPASB023.

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L’hème, une structure porphyrique contenant un atome de fer, est un cofacteur essentiel à de nombreuses fonctions bactériennes. Cependant, le fer de l’hème génère des radicaux libres, ce qui explique sa toxicité. Un des mécanismes principaux de détoxification de l’hème est l’expression, par les bactéries à Gram positif, d’un transporteur d’efflux de la famille ABC, HrtBA. La régulation de ce transporteur a été étudiée chez deux bactéries pathogènes opportunistes Enterococcus faecalis et Staphylococcus aureus, responsables d’infection nosocomiales multirésistantes. Chez E. faecalis, un nouveau
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24

Iltis, Corentin. "Effets du réchauffement climatique sur la performance d’un ravageur des cultures et impact sur les relations tritrophiques." Thesis, Bourgogne Franche-Comté, 2019. http://www.theses.fr/2019UBFCK051.

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Le réchauffement climatique va avoir des répercussions profondes sur les organismes vivants, en particulier les ectothermes comme les insectes, dont la physiologie et le comportement sont intimement liés à la température de leur environnement. Cette thèse propose d’étudier, par voie expérimentale, les conséquences du réchauffement climatique sur la performance d’un ravageur majeur de la vigne en Europe, l’eudémis (Lobesia botrana), et les conséquences pour l’interaction entre ce phytophage et les niveaux trophiques associés, en particulier les ennemis naturels (parasitoïdes). Les travaux se fo
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25

Parda, Kari Whitley. "Development and detection of bacterial soft rot of Hosta spp. Tratt. caused by Erwinia carotovora subsp. carotovora." 2001. http://purl.galileo.usg.edu/uga%5Fetd/whitley%5Fkari%5Fr%5F200112%5Fms.

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26

Tsai, Yi-Ying, and 蔡宜穎. "A Study on Personality Trait in ExcellentRadio Hosts." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/hsuyz7.

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碩士<br>國立臺北科技大學<br>技術及職業教育研究所<br>95<br>The purpose of this research were to study personality trait in excellent radio hosts, to understand what are the key personality traits of radio hosts, to analyze weather the personality trait of different excellent radio hosts has anything in common or in dissimilarity . This research applied the methods of case study by interviewing.The conclusions were as following: 1.Excellent radio hosts have some personality traits.These are positive emotions, values,ideas,feelings,altruism,deliberation,dutifulness,calm and aesthetics. 2.The key personality traits o
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27

Ko, Nai-Wen, and 柯乃文. "Host preference and trait variations of Liriomyza trifolii (Diptera: Agromyzidae)." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/30227237481282581462.

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碩士<br>國立臺灣大學<br>昆蟲學研究所<br>94<br>Liriomyza trifolii is a highly polyphagous and cosmopolitan pest. According to the investigation, the host range of L. trifolii has extensive embraced more than 400 species in 25 families. Females of L. trifolii lay eggs in the leaves; after hatching, larvae feed in the leaves and will not leave until pupation. Actually, females lay eggs in which host will determine the fate of the larvae; and that indicates the importance of the host preference of females. In this study, I used kidney bean (Phaseolus vulgaris) to rear L. trifolii stock at 24.5 ± 1˚C, 70 ± 10% R
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28

Bowen, Samantha. "Host Responses to Infection of the Upper and Lower Urinary Tract." Diss., 2013. http://hdl.handle.net/10161/7216.

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<p>Urinary tract infections (UTIs) are the second most common type of infection identified in the clinical setting and disproportionately afflict women. UTIs most frequently manifest in the form of infection of the lower urinary tract, involving the bladder. Uropathogens, particularly uropathogenic E. coli, progressively colonize the urethra and ascend to the bladder, where they initiate cystitis. In some cases, infection further ascends through the ureters and reaches the kidneys, where it causes pyelonephritis. Infection of both the upper and lower urinary tract can have serious ramification
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29

Dixit, Ojas V. A. "Within-host evolution and immigration of Escherichia coli in the human gastrointestinal tract." Master's thesis, 2017. http://hdl.handle.net/1885/119267.

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Several studies have shown that when a human host harbours two or more strains of E. coli, the second strain is significantly more likely to be a member of the same phylogroup than to be a member of a different phylogroup. Such an outcome may be the consequence of a within host evolution event or due an independent immigration/establishment event. To determine the relative importance of these two types of events in determining E. coli diversity in a host, a large collection of E. coli that consisted of up to 100 isolates recovered from each of 69 patients undergoing colonoscopies was used. Who
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30

Tseng, Chin-Chung, and 曾進忠. "The Roles of Host and Escherichia coli Virulence Factors in the Development of Upper Urinary Tract Infection and Emphysematous Pyelonephritis." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/78768075684861522652.

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博士<br>國立成功大學<br>臨床醫學研究所<br>93<br>Background: Upper urinary tract infection (UTI) is one of the major causes of morbidity and mortality for human. Escherichia coli is the most common pathogen for upper UTI. The putative virulence factors of E. coli include P-fimbriae, hemolysin and aerobactin; and the P-fimbriae is most frequently associated with upper UTI. The PapG adhesins at the tip of P-fimbriae mediate the binding with receptors on the uroepithelial cells. Recent studies have shown there are three variants of PapG adhesins. However, the roles of PapG adhesins subtypes, other fimbrial
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31

Baatjies, Roslynn. "Environmental and host factors associated with persistent lower respiratory tract symptoms or asthma following acute environmental exposure to sulphur dioxide (S02)." Thesis, 2007. http://hdl.handle.net/10539/2100.

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Student Number : 0316118X - MPH research report - School of Public Health - Faculty of Health Sciences<br>Introduction: On the weekend of 16 – 17 December 1995, the community of Macassar was exposed to elevated levels of sulphur dioxide vapours (SO2) caused by a fire on a nearby stockpile for approximately 21.5 hours. It has been estimated that community members were exposed to levels as high as 200 parts per million (ppm) of this gas as some 15 000 tons of the sulphur stockpile ignited. This resulted in a toxic plume of SO2 being blown over the Macassar area by the prevailing wind. Th
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32

Batista, Sónia Maria Gomes. "Use of probiotics in sole (Solea senegalensis) diets: effects on growth performance, host defense, morphology and ecology of the digestive tract." Doctoral thesis, 2016. https://repositorio-aberto.up.pt/handle/10216/83870.

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33

Batista, Sónia Maria Gomes. "Use of probiotics in sole (Solea senegalensis) diets: effects on growth performance, host defense, morphology and ecology of the digestive tract." Tese, 2016. https://repositorio-aberto.up.pt/handle/10216/83870.

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34

Mavromatis, Charalampos Harris. "Mapping of the Co-Transcriptomes of UPEC-Infected Macrophages Reveals New Insights into the Molecular Basis of Host-Pathogen Interactions in Human and Mouse." Diss., 2014. http://hdl.handle.net/10754/336484.

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Urinary tract infections (UTI) are among the most common infections in humans. Uropathogenic Escherichia coli (UPEC), the main causative agent of UTIs, can invade and replicate within bladder epithelial cells, and recent evidence demonstrated that some UPEC strains also survive within macrophages. To understand the mechanisms of host subversion that enable UPEC to survive within macrophages, and the contribution of macrophages to UPEC-mediated pathology, I performed host-pathogen co-transcriptome analyses using RNA sequencing. I developed an effective computational framework that simultaneousl
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35

Malihipour, Ali. "Genetic analysis of resistance to Fusarium head blight in wheat (Triticum spp.) using phenotypic characters and molecular markers." 2010. http://hdl.handle.net/1993/4284.

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Fusarium head blight (FHB), caused mainly by Fusarium graminearum (teleomorph: Gibberella zeae), is one of the most damaging diseases of wheat. A ‘Brio’/‘TC 67’ spring wheat population was used to map quantitative trait loci (QTLs) for resistance to FHB, and to study the association of morphological and developmental characteristics with FHB resistance. Interval mapping (IM) detected a major QTL on chromosome 5AL for resistance to disease severity (type II resistance) and Fusarium-damaged kernels (FDK) under greenhouse and field conditions, respectively. Inconsistent QTL(s) was also detected
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