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Relevant bibliographies by topics / Hot-melt extruded dosage forms

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Academic literature on the topic 'Hot-melt extruded dosage forms'

Author: Grafiati

Published: 4 June 2021

Last updated: 7 February 2022

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Journal articles on the topic "Hot-melt extruded dosage forms"

1

major, Ian, and Christopher McConville. "Hot Melt Extruded and Injection Moulded Dosage Forms: Recent Research and Patents." Recent Patents on Drug Delivery & Formulation 9, no. 3 (2015): 194–200. http://dx.doi.org/10.2174/1872211309666150512111143.

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Jones, David S., and Gavin P. Andrews. "ChemInform Abstract: Formulation and Characterisation of Hot Melt Extruded Dosage Forms: Challenges and Opportunities." ChemInform 41, no. 43 (2010): no. http://dx.doi.org/10.1002/chin.201043273.

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Zhu, Yucun, Ketan A. Mehta, and James W. McGinity. "Influence of Plasticizer Level on the Drug Release from Sustained Release Film Coated and Hot-Melt Extruded Dosage Forms." Pharmaceutical Development and Technology 11, no. 3 (2006): 285–94. http://dx.doi.org/10.1080/10409230600767551.

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4

Kipping, Thomas, and Hubert Rein. "Continuous production of controlled release dosage forms based on hot-melt extruded gum arabic: Formulation development, in vitro characterization and evaluation of potential application fields." International Journal of Pharmaceutics 497, no. 1-2 (2016): 36–53. http://dx.doi.org/10.1016/j.ijpharm.2015.11.021.

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Crișan, Andrea Gabriela, Alina Porfire, Rita Ambrus, et al. "Polyvinyl Alcohol-Based 3D Printed Tablets: Novel Insight into the Influence of Polymer Particle Size on Filament Preparation and Drug Release Performance." Pharmaceuticals 14, no. 5 (2021): 418. http://dx.doi.org/10.3390/ph14050418.

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Three-dimensional printing (3DP) by fused deposition modeling (FDM) has gained momentum as a promising pharmaceutical manufacturing method due to encouraging forward-looking perspectives in personalized medicine preparation. The current challenges the technology has for applicability in the fabrication of solid dosage forms include the limited range of suitable pharmaceutical grade thermoplastic materials. Hence, it is important to investigate the implications of variable properties of the polymeric carrier on the preparation steps and the final output, as versatile products could be obtained

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Young, Christopher R., Caroline Dietzsch, Matteo Cerea, et al. "Physicochemical characterization and mechanisms of release of theophylline from melt-extruded dosage forms based on a methacrylic acid copolymer." International Journal of Pharmaceutics 301, no. 1-2 (2005): 112–20. http://dx.doi.org/10.1016/j.ijpharm.2005.05.025.

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Cerda, Jose R., Talaya Arifi, Sejad Ayyoubi, et al. "Personalised 3D Printed Medicines: Optimising Material Properties for Successful Passive Diffusion Loading of Filaments for Fused Deposition Modelling of Solid Dosage Forms." Pharmaceutics 12, no. 4 (2020): 345. http://dx.doi.org/10.3390/pharmaceutics12040345.

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Although not readily accessible yet to many community and hospital pharmacists, fuse deposition modelling (FDM) is a 3D printing technique that can be used to create a 3D pharmaceutical dosage form by employing drug loaded filaments extruded via a nozzle, melted and deposited layer by layer. FDM requires printable filaments, which are commonly manufactured by hot melt extrusion, and identifying a suitable extrudable drug-excipient mixture can sometimes be challenging. We propose here the use of passive diffusion as an accessible loading method for filaments that can be printed using FDM techno

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Thakkar, Rishi, Miguel O. Jara, Steve Swinnea, Amit R. Pillai, and Mohammed Maniruzzaman. "Impact of Laser Speed and Drug Particle Size on Selective Laser Sintering 3D Printing of Amorphous Solid Dispersions." Pharmaceutics 13, no. 8 (2021): 1149. http://dx.doi.org/10.3390/pharmaceutics13081149.

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This research demonstrates the influence of laser speed and the drug particle size on the manufacturing of amorphous solid dispersions (ASD) and dosage forms thereof using selective laser sintering 3-dimensional (3D) printing. One-step manufacturing of ASD is possible using selective laser sintering 3D printing processes, however, the mechanism of ASD formation by this process is not completely understood and it requires further investigation. We hypothesize that the mechanism of ASD formation is the diffusion and dissolution of the drug in the polymeric carrier during the selective laser sint

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Govender, Rydvikha, Susanna Abrahmsén-Alami, Anette Larsson, Anders Borde, Alexander Liljeblad, and Staffan Folestad. "Independent Tailoring of Dose and Drug Release via a Modularized Product Design Concept for Mass Customization." Pharmaceutics 12, no. 8 (2020): 771. http://dx.doi.org/10.3390/pharmaceutics12080771.

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Independent individualization of multiple product attributes, such as dose and drug release, is a crucial overarching requirement of pharmaceutical products for individualized therapy as is the unified integration of individualized product design with the processes and production that drive patient access to such therapy. Individualization intrinsically demands a marked increase in the number of product variants to suit smaller, more stratified patient populations. One established design strategy to provide enhanced product variety is product modularization. Despite existing customized and/or

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10

Choi, Sung-Min, Sung-Hoon Lee, Chin-Yang Kang, and Jun-Bom Park. "Preparation of Hot-Melt Extruded Dosage Form for Enhancing Drugs Absorption Based on Computational Simulation." Pharmaceutics 12, no. 8 (2020): 757. http://dx.doi.org/10.3390/pharmaceutics12080757.

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The aim of this study was to control the dissolution rate and permeability of cilostazol. To enhance the dissolution rate of the active pharmaceutical ingredient (API), hot-melt extrusion (HME) technology was applied to prepare a solid dispersion (SD). To control permeability in the gastrointestinal tract regardless of food intake, the HME process was optimized based on physiologically based pharmacokinetic (PBPK) simulation. The extrudates were produced using a laboratory-scale twin-screw hot-melt extruder with co-rotatory screws and a constant feeding rate. Next, for PBPK simulation, paramet

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Dissertations / Theses on the topic "Hot-melt extruded dosage forms"

1

Zhang, Feng. "Hot-melt extrusion as a novel technology to prepare sustained-release dosage forms /." Digital version accessible at:, 1999. http://wwwlib.umi.com/cr/utexas/main.

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Maniruzzaman, Mohammed. "Development of hot-melt extrusion as a novel technique for the formulation of oral solid dosage forms." Thesis, University of Greenwich, 2012. http://gala.gre.ac.uk/9812/.

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Hot-melt extrusion (HME) is one of the most widely used technologies in the plastic, rubber and food industries and it has also been extensively explored and used in academia and the pharmaceutical industry over the last decade. This project aims to investigate the efficiency of hydrophilic polymers to enhance the dissolution rate of poorly water-soluble APIs processed by HME. Indomethacin (INM) and famotidine (FMT) were selected as model active substances while polyvinyl caprolactam graft copolymer, Soluplus® (SOL) and vinylpyrrolidone-vinyl acetate copolymer grades Kollidon® VA64 (VA64) and

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Deshmukh, Shivprasad S. "Investigation of injection moulding for novel drug delivery systems. An investigation into the use of injection moulding to produce pharmaceutical dosage forms and to understand the relationship between materials, processing conditions and performance, in particular drug release and stability." Thesis, University of Bradford, 2015. http://hdl.handle.net/10454/14302.

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The feasibility of the injection moulding (IM) was explored for the development of novel drug delivery systems. Controlled release formulations were developed using a substituted cellulose derivative, hydroxypropyl methyl cellulose acetate succinate (HPMCAS) and a graft co-polymer (Soluplus®). BCS class II drugs ibuprofen and the felodipine were selected based on their physicochemical properties. In the present work, a homogenous dispersion of drugs in the polymer matrices was achieved using Hot Melt Extrusion (HME) and extruded pellets obtained were used for the development of the injection

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Deshmukh, Shivprasad Shahajirao. "Investigation of injection moulding for novel drug delivery systems : an investigation into the use of injection moulding to produce pharmaceutical dosage forms and to understand the relationship between materials, processing conditions and performance, in particular drug release and stability." Thesis, University of Bradford, 2015. http://hdl.handle.net/10454/14302.

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Abstract:

The feasibility of the injection moulding (IM) was explored for the development of novel drug delivery systems. Controlled release formulations were developed using a substituted cellulose derivative, hydroxypropyl methyl cellulose acetate succinate (HPMCAS) and a graft co-polymer (Soluplus®). BCS class II drugs ibuprofen and the felodipine were selected based on their physicochemical properties. In the present work, a homogenous dispersion of drugs in the polymer matrices was achieved using Hot Melt Extrusion (HME) and extruded pellets obtained were used for the development of the injection m

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5

Crowley, Michael McDonald. "Physicochemical and mechanical characterization of hot-melt extruded dosage forms." Thesis, 2003. http://hdl.handle.net/2152/528.

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Crowley, Michael McDonald McGinity James W. "Physicochemical and mechanical characterization of hot-melt extruded dosage forms." 2003. http://wwwlib.umi.com/cr/utexas/fullcit?p3119662.

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Schilling, Sandra Ursula. "Implications of plasticization on the properties of hot-melt extruded oral dosage forms." 2009. http://hdl.handle.net/2152/7527.

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The influence of plasticization and other formulation factors on the properties of hot-melt extruded dosage forms for the controlled release of water-soluble active compounds was investigated. Citric acid monohydrate was demonstrated to function as a solid-state plasticizer in hot-melt extruded Eudragit® RS PO tablets and in cast films when concentrations below the compatibility limit were employed. Melting of the organic acid and solubilization in the polymer during extrusion were necessary to observe the plasticizing effect. The release rate of diltiazem hydrochloride, used as a high-melting

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Book chapters on the topic "Hot-melt extruded dosage forms"

1

Keen, Justin M., and James W. McGinity. "Melt Extruded Controlled Release Dosage Forms." In AAPS Advances in the Pharmaceutical Sciences Series. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-8432-5_10.

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"Melt-Extruded Controlled-Release Dosage Forms." In Pharmaceutical Extrusion Technology. CRC Press, 2003. http://dx.doi.org/10.1201/9780203911532-13.

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3

McGinity, James, and Feng Zhang. "Melt-Extruded Controlled-Release Dosage Forms." In Drugs and the Pharmaceutical Sciences. Informa Healthcare, 2003. http://dx.doi.org/10.1201/9780203911532.ch10.

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