Academic literature on the topic 'HPMC E15'

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Journal articles on the topic "HPMC E15"

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Perumalla, Ashok Kumar 1. *. Dr. Deenanath Jhade 2. "FORMULATION AND INVITRO EVALUATION OF RIZATRIPTAN ORAL THIN FILMS." Journal of Scientific Research in Pharmacy 7, no. 7 (2018): 74–78. https://doi.org/10.5281/zenodo.1318318.

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<strong><em>ABSTRACT</em></strong> <strong><em>I</em></strong><em>n present study oral thin films of Rizatriptan was developed to have a faster on set of action. The oral thin films were developed by using polymers HPMC E5, HPMC E 15 and PVP K90.Oral thin films were prepared by employing solvent casting method. Propylene glycol was selected as permeation enhancer and plasticizer. Drug excipient compatibility studies were carried out by using FTIR, and it was observed that there were no interactions. Formulations were prepared with the varying concentrations polymers ranging from F1-F12, and al
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Raziya, SK. "FORMULATION, EVALUATION OF MUCOADHESIVE BUCCAL FILM OF FELODIPINE USING FACTORIAL DESIGN." African Journal of Biological Sciences 6, no. 6 (2024): 7807–17. http://dx.doi.org/10.48047/afjbs.6.6.2024.7807-7817.

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The goal of the current study was to formulate and produce a felodipine buccal film that dissolves quickly utilising the solvent casting process. mucoadhesive polymers HPMC E15 and PVP were used to make mucoadhesive buccal films. Because HPMC E15 has a high mucoadhesive characteristic, it demonstrated an extended in-vitro residence period when compared to the other polymer
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Dr.A.Yasodha. "FORMULATION AND DEVELOPMENT OF ORAL DISSOLVING FILMS OF BUMETANIDE." iajps,csk publications 03, no. 11 (2016): 1424–36. https://doi.org/10.5281/zenodo.208205.

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Objective: Formulation and Development of oral dissolving Films of Bumetanide. Materials and methods: BUMETANIDE, HPMC E-50, HPMC E-5, HPMC E-3, PE, 4000 (Flakes) and Aspartame. Citric Acid could be formulated with low viscosity film formers viz. HPMC E50 in combination with HPMC E5, E15. Bumetanide could be successfully incorporated in FDFs with of the above polymers and polyethylene glycol 4000 is used as a plasticizer. PEG 4000 itself has a solubulizing affect and result in faster dissolution. Hence, there is no need of superdisintegrants. Use of low viscosity grade HPMC polymers resulted i
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Srilatha Malvey, Venkateshwar Rao J, and Kottaimuthu A. "Formulation of flurbiprofen transdermal patche: In vitro and Ex vivo report." International Journal of Research in Pharmaceutical Sciences 10, no. 4 (2019): 2661–69. http://dx.doi.org/10.26452/ijrps.v10i4.1524.

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The main aim of this study was to expand the present formulation with patch and to evaluate the transdermal patches of Flurbiprofen, NSAID (Non-Steroidal Anti-Inflammatory Drug) used in the treatment of arthritis. Flurbiprofen is required at a sustained rate of its short half- life (3-4 hours) long term percutaneous absorption is required for its gastrointestinal side effects. Hence in this study, an effort was done to develop transdermal patches of Flurbiprofen by employing a different combination of polymers were prepared by the solvent evaporation technique. Nine formulations were prepared
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Pallavi, K., and T. Pallavi. "FORMULATION AND EVALUATION OF FAST DISSOLVING FILMS OF ELETRIPTAN HYDROBROMIDE." International Journal of Current Pharmaceutical Research 9, no. 2 (2017): 59. http://dx.doi.org/10.22159/ijcpr.2017v9i2.17386.

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Objective: The main aim of the present research was to develop an oral fast dissolving polymeric film (FDF) with good mechanical properties, faster disintegration and dissolution when placed on the tongue.Methods: Eletriptan hydrobromide is prescribed for the treatment of mild to a moderate migraine. The polymers selected for preparing films were Pullulan, Maltodextrin (MDX), Acacia, Sodium alginate (SA), Locust bean gum (LBG), Guar gum (GG), Xanthan gum (XG), Polyvinyl alcohol (PVA), Polyvinyl pyrrolidine (PVP), Hydroxyl propyl methyl cellulose (HPMC) E5, and HPMC E15. Twelve sets of films FN
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Vaishali, R. Mahajan*1 Vasanti R. Mali2. "Rapid-Release Oral Films for Emergency Psychiatric Intervention: A Novel Formulation of Venlafaxine Hydrochloride." International Journal in Pharmaceutical Sciences 2, no. 10 (2024): 422–34. https://doi.org/10.5281/zenodo.13904697.

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This study focused on the successful formulation of orally dissolvable films (ODFs) of Venlafaxine using the solvent casting method. HPMC E15 and Gellan gum were employed as film-forming polymers at various concentrations (25%, 30%, and 35%). The optimized formulation (F13), which utilized equal proportions of HPMC E15 and Gellan gum (25%), demonstrated superior drug release rates, stability, and overall performance compared to formulations with individual polymers (F2 and F5). F13 also provided advantages such as rapid onset of action, increased bioavailability, avoidance of first-pass metabo
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Andrea, M. R., P. M. Dandagi, and A. P. Gadad. "FORMULATION AND EVALUATION OF FAST DISSOLVING BUCCAL FILMS OF DIMENHYDRINATE." INDIAN DRUGS 53, no. 09 (2016): 34–41. http://dx.doi.org/10.53879/id.53.09.10641.

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The aim of the present study was to develop a fast dissolving buccal film of dimenhydrinate with good mechanical properties and fast disintegration, producing an acceptable taste when placed in the mouth. The formulations were developed by solvent casting method by using HPMC E5 and HPMC E15 as film formers in different concentrations, propylene glycol as plasticizer and Poloxamer 407 as solubiliser. The resultant films were evaluated for various parameters. the films were found to be satisfactory for all the parameters. All formulations released more than 85% of the drug within 15 minutes. Fo
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Panraksa, Pattaraporn, Suruk Udomsom, Pornchai Rachtanapun, Chuda Chittasupho, Warintorn Ruksiriwanich, and Pensak Jantrawut. "Hydroxypropyl Methylcellulose E15: A Hydrophilic Polymer for Fabrication of Orodispersible Film Using Syringe Extrusion 3D Printer." Polymers 12, no. 11 (2020): 2666. http://dx.doi.org/10.3390/polym12112666.

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Extrusion-based 3D printing technology is a relatively new technique that has a potential for fabricating pharmaceutical products in various dosage forms. It offers many advantages over conventional manufacturing methods, including more accurate drug dosing, which is especially important for the drugs that require exact tailoring (e.g., narrow therapeutic index drugs). In this work, we have successfully fabricated phenytoin-loaded orodispersible films (ODFs) through a syringe extrusion 3D printing technique. Two different grades of hydroxypropyl methylcellulose (HPMC E5 and HPMC E15) were used
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Deepthi, V. Phani, AMPAPURAM RAJESH PAVAN, G. Naresh Babu, and K. Sreenivasulu. "Formulation and Evaluation of Prulifloxacin Sustained Release Matrix Tablets." Journal of Drug Delivery and Therapeutics 9, no. 4 (2019): 72–81. http://dx.doi.org/10.22270/jddt.v9i4.2974.

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Prulifloxacin is a chemotherapeutic antibiotic of Fluor quinolone drug used to treat a various urinary tract infections. It has short half-life, makes the sustained release (SR) forms extremely advantageous. Sustained release tablets results in increased bioavailability. The purpose of the present study was to develop a sustain release matrix drug delivery system (SR) containing Prulifloxacin as a model drug by using various proportions of polymers such as HPMC E15, HPMC K15. The sustained release formulations of Prulifloxacin were prepared by direct compression method. Optimization of formula
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Kumar, Y. Shravan, Deepthi B, and Mounika M. "Formulation and Evaluation of Salbutamol Sulphate Sublingual Films." International Journal of Pharmaceutical Sciences and Nanotechnology 10, no. 5 (2017): 3836–43. http://dx.doi.org/10.37285/ijpsn.2017.10.5.4.

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Salbutamol is a short-acting, selective beta-2-adrenergic receptor agonist used in treatment of asthma and COPD. In the present work, sublingual films of Salbutamol sulphate were developed with a view to enhance the patient compliance and provide quick onset of action. Salbutamol has a bioavailability of 53 - 60%. The goal of the study was to formulate sublingual films of Salbutamol sulphate to achieve a better dissolution rate and further improving the bioavailability of the drug. Sublingual films prepared by solvent casting method using film forming polymers HPMC-E5, HPMC-E15 and Maltodextri
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Dissertations / Theses on the topic "HPMC E15"

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Khotha, Doctor Elias. "Method development for determination and removal of the selected steroids from water sources in selected areas around the Vaal River in South Africa using High performance Liquid Chromatography, Macadamia Activated Carbon and Solid Phase Extraction." Thesis, 2018. http://hdl.handle.net/10352/443.

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M. Tech (Department of Chemistry, Faculty of Applied and Computer Sciences) Vaal University of Technology.<br>A simple and rapid method for determination of estrone (E1) and β-estradiol (E2) was developed and validated using high performance liquid chromatography (HPLC). The solutions of standards and sample were prepared with distilled water. HPLC separation was performed in isocratic method 50/50 (water/methanol) using 4.6 mm x 250 mm id film thickness 5 µm) XDB-C18 capillary column, detector DAD, UV on 254 nm, temperature 20 ºC with flow rate of 2 mL/min, sample volume 20 µL and run time of
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Conference papers on the topic "HPMC E15"

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Middya, Usuf, Abdulrahman Manea, Maitham Alhubail, Todd Ferguson, Thomas Byer, and Ali Dogru. "A Massively Parallel Reservoir Simulator on the GPU Architecture." In SPE Reservoir Simulation Conference. SPE, 2021. http://dx.doi.org/10.2118/203918-ms.

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Abstract Reservoir simulation computational costs have been continuously growing due to high-resolution reservoir characterization, increasing model complexity, and uncertainty analysis workflows. Reducing simulation costs by upscaling is often necessary for operational requirements. Fast evolving High-Performance-Computing (HPC) technologies offer opportunities to reduce cost without compromising fidelity. This work presents a novel in-house massively parallel full-physics reservoir simulator running on the emerging graphics processing unit (GPU) architecture. Almost all the simulation kernel
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Reports on the topic "HPMC E15"

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พงษ์สามารถ, สุนันท์, วิมลมาศ ลิปิพันธ์, ธิติรัตน์ ปานม่วง, ไกรสีห์ อัมพรายน์, เครือวัลย์ เอกรักษาศิลปชัย та นิจศิริ เรืองรังษี. การพัฒนาสารโพลี่แซคคาไรด์จากเปลือกของผลทุเรียน เพื่อใช้ทางการเภสัชกรรม : รายงานการวิจัย. จุฬาลงกรณ์มหาวิทยาลัย, 2001. https://doi.org/10.58837/chula.res.2001.27.

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เจลโพลี่แซคคาไรด์ (PG) และเส้นใยโพลี่แซคคาไรด์ (PF) สกัดได้จากเปลือกแห้งของผลทุเรียน (Durio zibethinus L.) ได้สารสกัด PG และ PF ประมาณ 7.3% และ 15.1% ของเปลือกแห้งตามลำดับ การวิเคราะห์ธาตุ พบว่าประกอบด้วย carbon (C) hydrogen (H) และ oxygen (O) ในอัตราส่วนอะตอมเท่ากับ 2.9:5.7:3.2 และ 3.5:6.4:3.1 ใน PG และ PF ตามลำดับและไม่พบมี nitrogen (N) และ sulfur (S) ในโพลี่แซคคาไรด์ทั้งสองชนิด PG มีส่วนประกอบของเส้นใย 96.3+-0.7% ซึ่งไม่พบมีเส้นใยอยู่ใน PF ผลการวิเคราะห์เกลือแร่ใน PG และ PF พบมีองค์ประกอบของโซเดียม โปแตสเซียม แคลเซียม แมกนีเซียม และมีจำนวนน้อยมากของเหล็ก ทองแดงสังกะสีและแมงกานีส องค์ประกอบข
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