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Dissertations / Theses on the topic 'HPMC etc'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Sealey-Voyksner, Jennifer A. Jorgenson James W. "Investigation of immunogenic gluten peptides identification using enzymatic tagging and HPLC-MSn; analysis and quantification using HPLC-MS/MS /." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2009. http://dc.lib.unc.edu/u?/etd,2764.

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Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2009.<br>Title from electronic title page (viewed Mar. 10, 2010). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Chemistry." Discipline: Chemistry; Department/School: Chemistry.

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2

McCulloch, Melissa. "Development of Quantitative Bioanalytical Methods for the Measurement of Pharmaceutical Compounds via HPLC-UV and HPLC-MS/MS." Cleveland State University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=csu1255046678.

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3

Benson, Andrew James. "High-performance liquid chromatography (HPLC) and high-performance liquid chromatography mass spectrometry (HPLC/MS) for the analysis of date rape drugs." FIU Digital Commons, 2002. http://digitalcommons.fiu.edu/etd/1602.

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The drugs studied in this work have been reportedly used to commit drug-facilitated sexual assault (DFSA), commonly known as "date rape". Detection of the drugs was performed using high-performance liquid chromatography with ultraviolet detection (HPLC/UV) and identified with high performance-liquid chromatography mass spectrometry (HPLC/MS) using selected ion monitoring (SIM). The objective of this study was to develop a single HPLC method for the simultaneous detection, identification and quantitation of these drugs. The following drugs were simultaneously analyzed: Gamma-hydroxybutyrate (GH

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4

Essaka, David Christian. "Reversed-Phase HPLC Determination of Cholesterol in Food Items." Digital Commons @ East Tennessee State University, 2007. https://dc.etsu.edu/etd/2034.

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Cholesterol is a fat-like molecule found among lipids in animal (including human) tissues. It is needed for maintaining good health. However, health issues have been raised because of the strong correlation between high levels of cholesterol in the body and cardiovascular disease. An HPLC method for quantitative determination of cholesterol in foods is presented. This involves a C-18 stationary phase using a 70:30 methanol: 2-propanol mobile phase with an UV detector set at 212 nm. The method showed linearity in the range 5.0 to 100.0 μg/mL and also good reproducibility with relative standard

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5

Zhang, Jie Zhang. "Designing and Building Efficient HPC Cloud with Modern Networking Technologies on Heterogeneous HPC Clusters." The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1532737201524604.

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6

Al-Saedi, Zahraa Hasan Falhi. "Formulation and In vitro Evaluation of Cyclosporine A Inserts Prepared Using HPMC for Treating Dry Eye Disease." University of Toledo Health Science Campus / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=mco1456095904.

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7

Crockett, Rachel Lynn. "The Physicochemical Properties of Gluten-Free Dough with the Addition of Hydrocolloids and Proteins." The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1251825675.

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8

O'Brien, Laura. "Mitochondrial biogenesis and electrical properties of hPSC-derived motor neurons." VCU Scholars Compass, 2015. http://scholarscompass.vcu.edu/etd/3804.

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Human pluripotent stem cells (hPSCs), including human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) hold great promise in the fields of drug development and regenerative medicine. If iPSCs reprogrammed from patient cells replicate what is seen in vivo they may be used as a model of disease. A process that is disrupted in many neurodegenerative diseases is mitochondrial biogenesis. One of these diseases is amyotrophic lateral sclerosis (ALS), which is characterized by loss of motor neurons in the brain and spinal cord. Differentiation of hPSCs into motor neurons offers

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9

Zhong, Fanyi. "DEVELOPMENT AND APPLICATIONS OF HPLC-MS/MS BASED METABOLOMICS." Miami University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=miami1524792637748877.

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10

Bharaj, Satinder Singh. "Development of Extended Release Dextromethorphan Matrix Tablets." University of Cincinnati / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1121780418.

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11

Chen, Taiyi. "Chloroperoxidase Catalyzed Enantioselective Epoxidation of Selected Olefins and Regiospecific Degradation of Dimethylsulfoniopropionate." FIU Digital Commons, 2011. http://digitalcommons.fiu.edu/etd/514.

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Chloroperoxidase (CPO), secreted by marine fungus Caldariomyces fumago, is the most versatile catalyst among known heme enzymes. Chloroperoxidase can catalyze epoxidation reactions with high enantioselectivity and high yield, which makes CPO an attractive candidate for both industrial and medicinal chiral synthesis. Toward this end, we have constructed two CPO mutants, F103A and N74V. Chiral HPLC was used to evaluate the enantioselectivity and yield of CPO and the mutants toward the epoxidation of styrene and its derivatives. Both of the mutants show dramatically changed epoxidation profiles c

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12

Lowe, Christian T. "Retention characteristics of water-soluable calixarene modified mobile phases in HPLC /." Connect to the full text of the document, 1998. http://www.ohiolink.edu/etd/view.cgi?ysu997550028.

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13

Frolova, Ana. "Biologiškai aktyvių junginių chromatografinė analizė paprastojo rapontiko (Rhaponticum carthamoides (DC.)Iljin) ekstraktuose." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2009. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2009~D_20090810_095853-61807.

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Paprastasis rapontikas (Rhaponticum carthamoides (DC.) Iljin) priklauso graižažiedžių šeimai, savaime augantis pietų Sibire [1]. Daugiametis žolinis augalas. Sinonimai: Leuzea carthamoides, Stemmacantha carthamoides, maralinė šaknis [2]. Paprastojo rapontiko ekstraktai pasižymi plačiu spektru teigiamo poveikio: pagerina miegą, apetitą, nuotaiką, fizinę ir psichinę būklę [3], druskų apytaką, virškinimą, stabdomas navikų vystymasis [4], stimuliuoja centrinę nervų, širdies ir kraujagyslių sistemas [1], pasižymi hipolipideminiu [5], psichostimuliuojančiu [4] vabzdžius atbaidančiu, imuninę sistemą

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14

Zdanytė, Birutė. "Antihistamininių vaistų (klemastino fumarato, loratadino, desloratadino) mišinio išskyrimas iš kraujo plazmos ir identifikavimas efektyviosios skysčių chromatografijos metodu." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2014~D_20140630_135949-87726.

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Darbo tikslas: optimizuoti metodiką, kuria būtų galima atlikti antihistamininių vaistų mišinio, sudaryto iš klemastino fumarato, loratadino ir desloratadino, ekstrakciją iš kraujo plazmos ir kokybinį nustatymą efektyviosios skysčių chromatografijos metodu. Darbo uždaviniai: Atlikti mokslinės literatūros analizę siekiant įvertinti antihistamininių vaistų savybes ir pasirinktų junginių ekstrakcijos iš kraujo plazmos ir tapatybės nusatymo metodikas. Optimizuoti ir validuoti ESC metodiką kokybiniam pasirinktų preparatų mišinio nustatymui iš kraujo plazmos. Parinkti klemastino fumarato, loratadino

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15

Sullenberger, Michael. "Chiral Calixarenes as Modifiers of Stationary and Mobile Phases in HPLC." Youngstown State University / OhioLINK, 2000. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1001956187.

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16

Mayton, Eric. "Characterization of Lysophosphatidic Acid Subspecies Using a Novel HPLC ESI-MS/MS Method." VCU Scholars Compass, 2011. http://scholarscompass.vcu.edu/etd/2515.

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Lysophosphatidic acid (LPA) is a bioactive lipid with a plethora of biological functions, including roles in cell survival, proliferation, and migration. Although high-performance liquid chromatography electrospray ionization tandem mass spectrometry (HPLC ESI-MS/MS) technology has been used to measure the levels of LPA in human blood, serum and plasma, current methods cannot readily detect the minute levels of LPA from cell culture. In this study, a novel HPLC ESI-MS/MS method with enhanced sensitivity was developed which allows accurate measurements of LPA levels with a limit of quantitation

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17

Samano, Kimberly L. "Behavioral Assessment and HPLC/MS/MS Identification of the Synthetic Cannabinoid, CP47,497, in Mice." VCU Scholars Compass, 2014. http://scholarscompass.vcu.edu/etd/3328.

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CP47,497 and other synthetic cannabinoid compounds were incipiently synthesized as research tools to investigate the mechanisms by which marijuana affects the brain and to aid in the development of therapeutic agents. Recently, these cannabinoid compounds have resurfaced in the designer drug market, marketed as “herbal incense products” (HIPs). Their popular use has resulted in an alarming rate of reported adverse effects and toxicities. Current legislation classified CP47,497 and several other synthetic cannabinoids compounds as Schedule I agents, but abuse of these compounds persists with se

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18

Zhang, Julie Zhiling. "The Toxicity Assessment of Heavy Metals and Their Species in Rice." University of Cincinnati / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1249602453.

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19

Sivasubramaniam, Ravishankar. "Performance Evaluation of LINQ to HPC and Hadoop for Big Data." UNF Digital Commons, 2013. http://digitalcommons.unf.edu/etd/463.

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There is currently considerable enthusiasm around the MapReduce paradigm, and the distributed computing paradigm for analysis of large volumes of data. The Apache Hadoop is the most popular open source implementation of MapReduce model and LINQ to HPC is Microsoft's alternative to open source Hadoop. In this thesis, the performance of LINQ to HPC and Hadoop are compared using different benchmarks. To this end, we identified four benchmarks (Grep, Word Count, Read and Write) that we have run on LINQ to HPC as well as on Hadoop. For each benchmark, we measured each system’s performance metrics (

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20

AL-Shaer, Mahmoud. "Reversed-Phase HPLC Determination of Citral in Locally Grown Lemon Grass Harvested at Different Season." Digital Commons @ East Tennessee State University, 2006. https://dc.etsu.edu/etd/2229.

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A simple HPLC procedure for the quantitative determination of citral, the major fragrant component in the lemon grass, has been developed. The procedure involves a C-8 stationary phase using a 90:10 methanol: water pH 5 mobile phase containing 0.25% 1-octanesulfonic acid and an UV detector (set at 233 nm). The lemon grass leaves were harvested fresh at different times of the year and were soaked in methanol for 48 hours without any mechanical assistance to extract the citral and other methanol soluble components. The method showed good reproducibility with relative standard deviation of 2.8% a

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21

Ansong, Godfred. "Analysis of plant polyphenols by high performance liquid chromatography/mass spectrometry and protein binding." Oxford, Ohio : Miami University, 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=miami1083081905.

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22

Apawu, Aaron Kwaku. "Reversed-Phase HPLC Determination of Alliin in Diverse Varieties of Fresh Garlic and Commercial Garlic Products." Digital Commons @ East Tennessee State University, 2009. https://dc.etsu.edu/etd/1803.

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Alliin is a predominant flavor precursor in garlic cloves. It interacts with the enzyme alliinase when garlic cloves are crushed, cut, or chewed to produce allicin, an unstable thiosulfinate that is the main biologically active component of fresh crushed garlic. Biological functions and health benefits of garlic include reduction of cancer risk in humans, improving immune system, and anti-microbial, anti-oxidant, and anti-hypertensive activities. The quality of fresh garlic and garlic products is usually related to its alliin content and allicin release potential. This research presents a s

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23

Kavaliauskis, Vilius. "BROMAZEPAMO, KLORAZEPATO IR NIMESULIDO MIŠINIO TYRIMAS INSTRUMENTINĖS ANALIZĖS METODAIS." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2014~D_20140618_233622-89523.

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Tikslas: optimizuoti instrumentinės analizės metodus (plonasluoksnė chromatografija ir efektyvioji skysčių chromatografija) bromazepamo, klorazepato ir nimesulido mišinio išskirstymui ir komponentų identifikavimui.Uždaviniai:optimizuoti bromazepamo, klorazepato, nimesulido mišinio komponentų atskyrimą ir identifikavimą plonasluoksnės chromatografijos metodu. Optimizuoti plonasluoksnės chromatografijos metodą kiekybiniam bromazepamo, klorazepato ir nimesulido nustatymui. Optimizuoti bromazepamo, klorazepato, nimesulido mišinio komponentų atskyrimą ir identifikavimą efektyviosios skysčių chromat

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24

Klute, Robert Cragg. "Enantiomeric separations by HPLC : temperature, mobile phase, flow rate and retention mechanism studies /." This resource online, 1993. http://scholar.lib.vt.edu/theses/available/etd-06062008-171241/.

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25

Perdue, James D. "The removal of Cremophor® EL from paclitaxel for quantitative analysis by HPLC-UV /." Electronic version (PDF), 2005. http://dl.uncw.edu/etd/2005/perduej/jamesperdue.pdf.

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26

Almassalkhi, Brittany A. "Arsenic Speciation, Detection, and Quantification in Drinking Water using High Performance Liquid Chromatography and Inductively Coupled Plasma Mass Spectrometry." University of Cincinnati / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1258580087.

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27

Majeti, Jailakshmi Manasa. "Structural Characteristics of Vpr Protein." Youngstown State University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1299529352.

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28

Zhang, Bohua. "The Influence of Porosity and Its Modeling on Fatigue Behavior of High Pressure Die Cast Aluminum including the Effects of Mean Stress, Stress Gradient and Specimen Size." University of Toledo / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1556259677391458.

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29

Akshay, Venkatesh. "High-Performance Heterogeneity/ Energy-Aware Communication for Multi-Petaflop HPC Systems." The Ohio State University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=osu1483522226773739.

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30

Biswas, Rajarshi. "Benchmarking and Accelerating TensorFlow-based Deep Learning on Modern HPC Systems." The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1531827968620294.

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31

Tawfik, Rahmy. "A Novel Approach to the Discovery of Natural Products From Actinobacteria." Scholar Commons, 2017. http://scholarcommons.usf.edu/etd/6766.

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Actinobacteria, primarily the genus Streptomyces, have led to the development of a number of antibiotics, which result from their secondary metabolites or modified derivatives. Secondary metabolite production can result from competition with neighboring microbes in an effort to disrupt growth, aiding in the competition for vital nutrients in impoverished conditions. Such secondary metabolites have the potential to affect a plethora of cellular functions in target cells, including, cell wall development, protein synthesis, protein function and fatty acid synthesis/metabolism. Due to the pandemi

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32

Eliser, Erica E. "Synthesis and Characterization of Amino-derived t-butyl-calix[4]arene Bonded Phases for HPLC." Youngstown State University / OhioLINK, 2001. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1008341180.

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33

Ariyaratne, Menaka M. "HPLC Analysis of Polyamines in Arabidopsis Thaliana Lines Altered in the Expression of Polyamine Transport." Bowling Green State University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1404039834.

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34

Marin, Córdoba Roberto. "Chromium carcinogenesis characterization of DNA damaging intermediates by EPR ³¹P NMR, HPLC, ESI-MS and magnetic susceptibility /." Ohio : Ohio University, 2010. http://www.ohiolink.edu/etd/view.cgi?ohiou1261417590.

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35

Kathiwala, Mehjabin Abdul Majid. "Measurement of stress and disease markers in biological fluids by fast scan cyclic voltammetry and HPLC-UV." [Gainesville, Fla.] : University of Florida, 2009. http://purl.fcla.edu/fcla/etd/UFE0024706.

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36

Bayatpour, Mohammadreza. "Designing High Performance Hardware-assisted Communication Middlewares for Next-Generation HPC Systems." The Ohio State University, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=osu1619140614941402.

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37

Hribar, James Anthony. "Capillary Gradient Chromatofocusing-Mass Spectrometry: A Sensitive Approach for Protein Analysis." Cleveland State University / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=csu1306436593.

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38

Zhang, Zhaoqi. "Stability Studies of MOMIPP, an Inducer of Methuosis." University of Toledo Health Science Campus / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=mco1418402908.

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39

Wei, Wenjun. "Wide bore tube electrophoresis using Pluronic polymer gels in conjunction with spectrophotometry, HPLC, and MALDI/MS." Miami University / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=miami1375056442.

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40

Hall, Rachael Catherine. "KERATIN HYDROGELS FOR ANTIBIOTIC DELIVERY IN WOUND HEALING APPLICATIONS: DEVELOPMENT OF HPLC METHODS TO CHARACTERIZE RELEASE." Miami University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=miami1407435625.

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41

Reeves, Savanah Gail. "Condensed tannin characterization with FT-ICR MALDI mass spectrometry and separation with saw-tooth gradient HPLC." Miami University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=miami1591185101154831.

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42

Sexton, Danessa Leann. "Determination of lactose by reversed-phase high performance liquid chromatography." [Johnson City, Tenn. : East Tennessee State University], 2004. http://etd-submit.etsu.edu/etd/theses/available/etd-0328104-212023/unrestricted/SextonD041504f.pdf.

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Thesis (M.S.)--East Tennessee State University, 2004.<br>Title from electronic submission form. ETSU ETD database URN: etd-0328104-212023. Includes bibliographical references. Also available via Internet at the UMI web site.

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43

Kurantavičius, Vytautas. "Dobilų (Trifolium L.) genties augalų izoflavonų kiekybinės sudėties tyrimas." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2010. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2010~D_20100621_095209-97450.

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Tyrimo objektas ir metodai: dobilų genties augalų lapų, stiebų, žiedų žaliavų tyrimas. Izoflavonai nustatyti ESC metodu. Darbo tikslas: Atlikti izoflavonų genisteino, formononetino ir daidzeino analizę dobilų genties augaluose, taikant ESC metodą. Darbo uždaviniai: atlikti literatūros analizę, apibendrinant dobilų (Trifolium L) genties augalų biologines savybes, izoflavonų taikymą gydymo tikslais ir nustatymo metodus. Parinkti ekstrakcijos sąlygas, įvertinant pasirinkto ekstrakcijos tirpiklio, jo poliškumo ir ekstrakcijos laiko įtaką. Optimizuoti ESC metodą dobilų žaliavos tyrimui ir pagrįsti

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44

Zykevičiūtė, Justina. "Vaistinių arbatų sudėties ir antioksidacinių savybių įvertinimas." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2009. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2009~D_20090810_100522-62256.

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Vaistinės arbatos mišiniai vertingi dėl jose esančių komponentų, kaip fenoliniai junginiai (atsakingi už antimikrobinį veikimą) ir flavonoidai (natūralūs antioksidantai, surišantys laisvuosius radikalus). Flavonoidų cheminės savybės apžvelgtos darbe. Šio darbo tikslas - atlikti flavonoidų ir fenolinių junginių kiekybinę ir kokybinę analizę bei nustatyti bendrą antioksidacinį aktyvumą vaistinių arbatų mišinių ekstraktuose. Paruošti metanoliniai vaistinių arbatų mišinių ekstraktai po kietafazės ekstrakcijos buvo analizuojami spektrofotometru, kapiliarine elektroforeze ir efektyviąja skysčių chro

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45

Shankar, Dipti. "Designing Fast, Resilient and Heterogeneity-Aware Key-Value Storage on Modern HPC Clusters." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1563522337179638.

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46

Chu, Ching-Hsiang. "Accelerator-enabled Communication Middleware for Large-scale Heterogeneous HPC Systems with Modern Interconnects." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1595451131152.

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47

Chen, Ping. "Pharmacokinetic-Pharmacodynamic Studies Of 5-Azacytidine In Combination With Gti-2040." The Ohio State University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=osu1221854928.

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48

Bottegal, Megan N. "The Development of High Performance Liquid Chromatography Systems for the Analysis of Improvised Explosives." FIU Digital Commons, 2010. http://digitalcommons.fiu.edu/etd/154.

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Existing instrumental techniques must be adaptable to the analysis of novel explosives if science is to keep up with the practices of terrorists and criminals. The focus of this work has been the development of analytical techniques for the analysis of two types of novel explosives: ascorbic acid-based propellants, and improvised mixtures of concentrated hydrogen peroxide/fuel. In recent years, the use of these explosives in improvised explosive devices (IEDs) has increased. It is therefore important to develop methods which permit the identification of the nature of the original explosive fro

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49

Whitchurch, Christian J. "Development of a Novel Electrochemiluminescent Reaction Involving Cadmium." Ohio University / OhioLINK, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1011035988.

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50

DONALD, GREGORY THOMAS. "Model Chiral Ionic Liquids for High Performance Liquid Chromatography Stationary Phases." University of Cincinnati / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1214325450.

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