Relevant bibliographies by topics / HPP1 gene

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Academic literature on the topic 'HPP1 gene'

Author: Grafiati
Published: 4 June 2021
Last updated: 6 February 2022

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Journal articles on the topic "HPP1 gene"

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Ebert, Matthias P. A., Suzanne H. Mooney, Lori Tonnes-Priddy, et al. "Hypermethylation of the TPEF/HPP1 Gene in Primary, Metastatic Colorectal Cancers." Neoplasia 7, no. 8 (2005): 771–78. http://dx.doi.org/10.1593/neo.05235.

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Young, J., K. G. Biden, L. A. Simms, et al. "HPP1: A transmembrane protein-encoding gene commonly methylated in colorectal polyps and cancers." Proceedings of the National Academy of Sciences 98, no. 1 (2001): 265–70. http://dx.doi.org/10.1073/pnas.98.1.265.

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Ivanauskas, A., J. Hoffmann, L. V. Jonaitis, et al. "Distinct TPEF/HPP1 gene methylation patterns in gastric cancer indicate a field effect in gastric carcinogenesis." Digestive and Liver Disease 40, no. 12 (2008): 920–26. http://dx.doi.org/10.1016/j.dld.2008.05.004.

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Scougall, KT, CA Maltin, and JA Shaw. "Tetracycline-regulated secretion of human insulin in a transfected non-endocrine cell line." Journal of Molecular Endocrinology 30, no. 3 (2003): 331–46. http://dx.doi.org/10.1677/jme.0.0300331.

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Long-term constitutive secretion of insulin by implantation of ex vivo transfected cells such as fibroblasts or myoblasts or in situ by intramuscular injection of naked plasmid DNA provides a potential approach to gene therapy for diabetes mellitus. A mechanism for regulating insulin secretion will be necessary to realize the therapeutic potential of this approach. A second obstacle is the inability of non-endocrine host cells to fully process proinsulin. Therefore, alteration of the wild-type cDNA will be necessary to achieve processing of proinsulin by endogenous endoproteases within these c
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Aguilera, A., and H. L. Klein. "Genetic and molecular analysis of recombination events in Saccharomyces cerevisiae occurring in the presence of the hyper-recombination mutation hpr1." Genetics 122, no. 3 (1989): 503–17. http://dx.doi.org/10.1093/genetics/122.3.503.

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Abstract The hyper-recombination mutation hpr1 specifically increases mitotic intrachromatid crossovers, with no effect on other mitotic recombination events such as unequal sister chromatid exchange and plasmid-chromosome recombination, and no effect on meiotic recombination and a lesser effect on intrachromosomal gene conversion. The excision repair RAD1 gene is partially required for the expression on the hpr1 phenotype. The simplest hypothesis to account for some of the hpr1 stimulated recombination events is that a heteroduplex DNA intermediate and localized gene conversion are involved.
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Aguilera, A., and H. L. Klein. "HPR1, a novel yeast gene that prevents intrachromosomal excision recombination, shows carboxy-terminal homology to the Saccharomyces cerevisiae TOP1 gene." Molecular and Cellular Biology 10, no. 4 (1990): 1439–51. http://dx.doi.org/10.1128/mcb.10.4.1439.

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The HPR1 gene has been cloned by complementation of the hyperrecombination phenotype of hpr1-1 strains by using a color assay system. HPR1 is a gene that is in single copy on chromosome IV of Saccharomyces cerevisiae, closely linked to ARO1, and it codes for a putative protein of 752 amino acids (molecular mass, 88 kilodaltons). Computer searches revealed homology (48.8% conserved homology; 24.8% identity) with the S. cerevisiae TOP1 gene in an alpha-helical stretch of 129 amino acids near the carboxy-terminal region of both proteins. The ethyl methanesulfonate-induced hpr1-1 mutation is a sin
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Aguilera, A., and H. L. Klein. "HPR1, a novel yeast gene that prevents intrachromosomal excision recombination, shows carboxy-terminal homology to the Saccharomyces cerevisiae TOP1 gene." Molecular and Cellular Biology 10, no. 4 (1990): 1439–51. http://dx.doi.org/10.1128/mcb.10.4.1439-1451.1990.

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The HPR1 gene has been cloned by complementation of the hyperrecombination phenotype of hpr1-1 strains by using a color assay system. HPR1 is a gene that is in single copy on chromosome IV of Saccharomyces cerevisiae, closely linked to ARO1, and it codes for a putative protein of 752 amino acids (molecular mass, 88 kilodaltons). Computer searches revealed homology (48.8% conserved homology; 24.8% identity) with the S. cerevisiae TOP1 gene in an alpha-helical stretch of 129 amino acids near the carboxy-terminal region of both proteins. The ethyl methanesulfonate-induced hpr1-1 mutation is a sin
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Santos-Rosa, H., and A. Aguilera. "Isolation and genetic analysis of extragenic suppressors of the hyper-deletion phenotype of the Saccharomyces cerevisiae hpr1 delta mutation." Genetics 139, no. 1 (1995): 57–66. http://dx.doi.org/10.1093/genetics/139.1.57.

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Abstract The HPR1 gene of Saccharomyces cerevisiae is involved in maintaining low levels of deletions between DNA repeats. To understand how deletions initiate in the absence of the Hpr1 protein and the mechanisms of recombination leading to deletions in S. cerevisiae, we have isolated mutations as suppressors of the hyper-deletion phenotype of the hpr1 delta mutation. The mutations defined five different genes called HRS for hyper-recombination suppression. They suppress the hyper-deletion phenotype of hpr1 delta strains for three direct repeat systems tested. The mutations eliminated the hyp
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Kosař, Michal, Lumila Holková, Natálie Březinová Belcredi, and Jaroslava Ehrenbergerová. "HPPD gene expression in relation to vitamin E content in spring barley." Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis 57, no. 4 (2009): 13–18. http://dx.doi.org/10.11118/actaun200957040013.

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The enzyme 4-hydroxyphenylpyruvate dioxygenase (HPPD) has a very important role in the biosynthetic pathway of vitamin E. Its activity influences the final level of tocols in plant tissues. Seven barley cultivars with different vitamin E level were grown under control conditions and activity of HPPD gene was measured four, eight and twelve days after pollination of ear tissues. It was found that activity of HPPD gene corresponded with vitamin E content detected in grains (r = 0.77*). The relationship between the gene activity for HPPD eight and twelve days after pollination and vitamin E conte
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Sun, Yi, Yuke Tian, Haifeng Li, Dengwen Zhang, and Qiang Sun. "Antinociceptive Effect of Intrathecal Injection of Genetically Engineered Human Bone Marrow Stem Cells Expressing the Human Proenkephalin Gene in a Rat Model of Bone Cancer Pain." Pain Research and Management 2017 (2017): 1–11. http://dx.doi.org/10.1155/2017/7346103.

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Background. This study aimed to investigate the use of human bone marrow mesenchymal stem cells (hBMSCs) genetically engineered with the human proenkephalin (hPPE) gene to treat bone cancer pain (BCP) in a rat model.Methods. Primary cultured hBMSCs were passaged and modified with hPPE, and the cell suspensions (6 × 106) were then intrathecally injected into a rat model of BCP. Paw mechanical withdrawal threshold (PMWT) was measured before and after BCP. The effects of hPPE gene transfer on hBMSC bioactivity were analyzed in vitro and in vivo.Results. No changes were observed in the surface phe
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Dissertations / Theses on the topic "HPP1 gene"

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Ivanauskas, Audrius. "Ankstyvos skrandžio vėžio bei ikivėžinių būklių diagnostikos galimybių įvertinimas." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2008. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2008~D_20080319_133515-70953.

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Visame pasaulyje skrandžio vėžys yra didelė problema, kasmet diagnozuojama apie 875000 naujų atvejų ir 645000 miršta nuo šios ligos. Lietuvos vėžio registro duomenimis, 2005 m. Lietuvoje sergamumas skrandžio vėžiu buvo 35,0 vyrų ir 22,1 moterų tarpe 100000 gyventojų. Šis susirgimas vis dar dažniausiai diagnozuojamas vėlyvose stadijose, kuomet radikali operacija jau nėra galima. Skrandžio vėžio vystymasis yra kompleksinis ir šiuo metu dar pilnai neišaiškintas procesas. Nauji tyrimai patvirtino, kad epigenetinė pažaida – TPEF/HPP1 geno metilinimas yra dažnas reiškinys tulžies ir šlapimo pūsles,
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Kazazi, Dorothea. "Identification of endogenous genes regulated by heterochromatin protein 1 (HP1) in vivo." Thesis, Imperial College London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.429490.

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Thiour, Mauprivez Clémence. "DIAGSOL : développement d’un nouveau marqueur fonctionnel d’exposition aux herbicides β-tricétones dans un sol agricole Effects of herbicide on non-target microorganisms: towards a new class of biomarkers? Assessing the effects of β-triketone herbicides on bacterial HPPD: from a molecular study to an enzymatic assay Design of a degenerate primer pair to target a bacterial functional community: The hppd bacterial gene coding for the enzyme targeted by herbicides, a study case Assessing the Effects of β-Triketone Herbicides on the Soil Bacterial and hppd Communities: A Lab-to-Field Experiment". Thesis, Perpignan, 2020. http://www.theses.fr/2020PERP0025.

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De nombreux herbicides ciblent une enzyme végétale aussi retrouvée chez des organismes dits « non-cibles » tels que les microorganismes. Ce travail de thèse vise à établir la preuve de concept que les gènes microbiens codant l’enzyme ciblée ou l’activité de l’enzyme elle-même peuvent servir de marqueur d’impact écotoxicologique des herbicides dans les sols. L’enzyme HPPD (4-hydroxyphénylpyruvate dioxygénase) et le gène du même nom, cible des herbicides bêta-tricétones, sont sujets d’étude. Des études in silico montrent que le gène hppd est présent dans de nombreux genres bactériens et un coupl
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Li, Hui. "COOPERATIVE AND ANTAGONISTIC ROLES FOR HETEROCHROMATIN PROTEINS IN TRANSCRIPTIONAL REGULATION OF THE DROSOPHILA SEX DETERMINATION MASTERSWITCH GENE." UKnowledge, 2011. http://uknowledge.uky.edu/gradschool_diss/127.

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HOAP was originally identified as a component of an ORC-containing multi-protein complex of Heterochromatin Protein 1 (HP1) from early Drosophila embryos. HOAP immunostaining showed prominent association of it with telomeres, and mutants for HOAP (cav1) showed it functions along with HP1 in forming a telomere capping complex that prevents telomeric fusions. Weaker HOAP immunostaining is also observed in regions of pericentric heterochromatin and euchromatin. To examine the role of HOAP at these non-telomeric sites, we applied Affymetric Drosophila Genome Arrays to undertake a microarray expres
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Wiese, Meike. "Characterisation of HP1γ in mammalian cells". Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/273362.

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The degree of chromatin compaction plays a fundamental role in controlling the accessibility of DNA to the transcription machinery as well as other DNA-dependent biological pathways. The mammalian HP1 (Heterochromatin protein 1) protein family consists of three members: HP1α, β and γ. Each paralogue regulates formation and maintenance of heterochromatin by binding to the repressive chromatin marks H3K9me2/3 with their chromodomains (CDs). Despite high sequence conservation, each HP1 paralogue possesses specific functions, which are likely to be cell type specific. The aim of my thesis was to f
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Bretes, Rodrigues Hugo. "Etude de la régulation du métabolisme des ARN messagers chez la levure Saccharomyces cerevisiae." Thesis, Paris 11, 2012. http://www.theses.fr/2012PA112209.

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Au cours de la transcription, plusieurs facteurs sont assemblés sur les ARN messagers pour former des Ribonucléoparticules de messagers (mRNPs), et contrôler leur maturation, leur stabilité et leur devenir dans le cytoplasme. Afin d’assurer la production de protéines fonctionnelles, la cellule dispose de plusieurs mécanismes de régulation et de contrôle de qualité assurant la fidélité de l’information génétique transmise au niveau ARN messager et protéine.Chez la levure Saccharomyces cerevisiae, un ensemble de protéines associées au pore nucléaire, incluant la SUMO protéase Ulp1, a été impliqu
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Daniels, Linchay Janine. "Phenotypic characterization and genetic variation of viramin E genes in sunflower." Diss., 2017. http://hdl.handle.net/10500/23594.

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Sunflower (Helianthus annuus) consists of high levels of polyunsaturated fatty acids, making its oil susceptible to oxidation. Tocopherols can retard or prevented oxidation. The aim of this study is to determine the phenotypic tocopherol (vitamin E) composition and genetic diversity of the biosynthetic pathway genes. Seeds were characterized for fatty acid and tocopherol content. A positive correlation was found between oleic acid, γ (r =0.17) and δ (r =0.23) tocopherol but none between linoleic acid and all four tocopherol derivatives. Vitamin E gene homologues were identified and a co
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Reports on the topic "HPP1 gene"

1

Tanese, Naoko. Identification of HP1 Target Genes Involved in Progression of Breast Cancer. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada430474.

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