Relevant bibliographies by topics / HPSC

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'HPSC'

Author: Grafiati
Published: 4 June 2021
Last updated: 21 December 2024

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Journal articles on the topic "HPSC"

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Hayashi, Yohei, and Miho Kusuda Furue. "Biological Effects of Culture Substrates on Human Pluripotent Stem Cells." Stem Cells International 2016 (2016): 1–11. http://dx.doi.org/10.1155/2016/5380560.

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In recent years, as human pluripotent stem cells (hPSCs) have been commonly cultured in feeder-free conditions, a number of cell culture substrates have been applied or developed. However, the functional roles of these substrates in maintaining hPSC self-renewal remain unclear. Here in this review, we summarize the types of these substrates and their effect on maintaining hPSC self-renewal. Endogenous extracellular matrix (ECM) protein expression has been shown to be crucial in maintaining hPSC self-renewal. These ECM molecules interact with integrin cell-surface receptors and transmit their c
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Vojnits, Kinga, Mio Nakanishi, Deanna Porras, et al. "Developing CRISPR/Cas9-Mediated Fluorescent Reporter Human Pluripotent Stem-Cell Lines for High-Content Screening." Molecules 27, no. 8 (2022): 2434. http://dx.doi.org/10.3390/molecules27082434.

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Application of the CRISPR/Cas9 system to knock in fluorescent proteins to endogenous genes of interest in human pluripotent stem cells (hPSCs) has the potential to facilitate hPSC-based disease modeling, drug screening, and optimization of transplantation therapy. To evaluate the capability of fluorescent reporter hPSC lines for high-content screening approaches, we targeted EGFP to the endogenous OCT4 locus. Resulting hPSC–OCT4–EGFP lines generated expressed EGFP coincident with pluripotency markers and could be adapted to multi-well formats for high-content screening (HCS) campaigns. However
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Hai, Nan, Dong Shin, Huanjing Bi, Kaiming Ye, and Sha Jin. "Mechanistic Analysis of Physicochemical Cues in Promoting Human Pluripotent Stem Cell Self-Renewal and Metabolism." International Journal of Molecular Sciences 19, no. 11 (2018): 3459. http://dx.doi.org/10.3390/ijms19113459.

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We have previously reported that a porous membrane of polyethylene terephthalate (PET) enables significant augmentation of human pluripotent stem cell (hPSC) proliferation and differentiation. The interaction between hPSCs and the PET surface induces β-catenin-mediated wingless/integrated (Wnt) signaling, leading to upregulation of the expression of adhesion molecules in hPSCs. In this study, we sought to unveil mechanisms underlying the role of the PET membrane in hPSC self-renewal and metabolism. We discovered that physicochemical cues of the PET membrane considerably alter hPSC metabolism b
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Lim, Seakcheng, Rachel A. Shparberg, Jens R. Coorssen, and Michael D. O’Connor. "Application of the RBBP9 Serine Hydrolase Inhibitor, ML114, Decouples Human Pluripotent Stem Cell Proliferation and Differentiation." International Journal of Molecular Sciences 21, no. 23 (2020): 8983. http://dx.doi.org/10.3390/ijms21238983.

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Retinoblastoma binding protein 9 (RBBP9) is required for maintaining the expression of both pluripotency and cell cycle genes in human pluripotent stem cells (hPSCs). An siRNA-based study from our group showed it does so by influencing cell cycle progression through the RB/E2F pathway. In non-pluripotent cells, RBBP9 is also known to have serine hydrolase (SH) activity, acting on currently undefined target proteins. The role of RBBP9 SH activity in hPSCs, and during normal development, is currently unknown. To begin assessing whether RBBP9 SH activity might contribute to hPSC maintenance, hPSC
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Buchholz, David E., Thomas S. Carroll, Arif Kocabas, et al. "Novel genetic features of human and mouse Purkinje cell differentiation defined by comparative transcriptomics." Proceedings of the National Academy of Sciences 117, no. 26 (2020): 15085–95. http://dx.doi.org/10.1073/pnas.2000102117.

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Comparative transcriptomics between differentiating human pluripotent stem cells (hPSCs) and developing mouse neurons offers a powerful approach to compare genetic and epigenetic pathways in human and mouse neurons. To analyze human Purkinje cell (PC) differentiation, we optimized a protocol to generate human pluripotent stem cell-derived Purkinje cells (hPSC-PCs) that formed synapses when cultured with mouse cerebellar glia and granule cells and fired large calcium currents, measured with the genetically encoded calcium indicator jRGECO1a. To directly compare global gene expression of hPSC-PC
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Armstrong, Alison J., Hal Hansen, and Roger Gauthier. "Development of a Model for Evaluating High Performance Sport Centers in Canada." Journal of Sport Management 5, no. 2 (1991): 153–76. http://dx.doi.org/10.1123/jsm.5.2.153.

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A theory based model was developed for the evaluation of high performance sport centers (HPSCs) in Canada. The model was developed according to de Groot’s (1969) four-phase interpretative-theoretical methodology. The phases of exploration, analysis, classification, and explanation guided the collection of current program evaluation literature and information on the nature of the HPSC program and its past evaluation practices. Appropriate evaluation models from the literature were assessed with respect to the HPSC program’s nature, and a single theoretical-integrative model was developed with c
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Yamada, Daisuke, Tomoka Takao, Masahiro Nakamura, Toki Kitano, Eiji Nakata, and Takeshi Takarada. "Identification of Surface Antigens That Define Human Pluripotent Stem Cell-Derived PRRX1+Limb-Bud-like Mesenchymal Cells." International Journal of Molecular Sciences 23, no. 5 (2022): 2661. http://dx.doi.org/10.3390/ijms23052661.

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Stem cell-based therapies and experimental methods rely on efficient induction of human pluripotent stem cells (hPSCs). During limb development, the lateral plate mesoderm (LPM) produces limb-bud mesenchymal (LBM) cells that differentiate into osteochondroprogenitor cells and form cartilage tissues in the appendicular skeleton. Previously, we generated PRRX1-tdTomato reporter hPSCs to establish the protocol for inducing the hPSC-derived PRRX1+ LBM-like cells. However, surface antigens that assess the induction efficiency of hPSC-derived PRRX1+ LBM-like cells from LPM have not been identified.
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Ghosheh, Nidal, Barbara Küppers-Munther, Annika Asplund, et al. "Comparative transcriptomics of hepatic differentiation of human pluripotent stem cells and adult human liver tissue." Physiological Genomics 49, no. 8 (2017): 430–46. http://dx.doi.org/10.1152/physiolgenomics.00007.2017.

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Hepatocytes derived from human pluripotent stem cells (hPSC-HEP) have the potential to replace presently used hepatocyte sources applied in liver disease treatment and models of drug discovery and development. Established hepatocyte differentiation protocols are effective and generate hepatocytes, which recapitulate some key features of their in vivo counterparts. However, generating mature hPSC-HEP remains a challenge. In this study, we applied transcriptomics to investigate the progress of in vitro hepatic differentiation of hPSCs at the developmental stages, definitive endoderm, hepatoblast
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Walasek, Marta A., Crystal Chau, Christian Barborini, et al. "A Reproducible and Simple Method to Generate Red Blood Cells from Human Pluripotent Stem Cells." Blood 134, Supplement_1 (2019): 1189. http://dx.doi.org/10.1182/blood-2019-128830.

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Erythroid cells generated from human pluripotent stem cells (hPSCs) can potentially offer an unlimited and safe supply of red blood cells (RBCs) for transfusion. Human PSC-derived erythroid cells at various stages of differentiation can also be used to model blood diseases, test new drug candidates, and develop cellular and genetic therapies. Although several protocols for deriving RBCs from hPSCs have been described, these are typically complex, involving multiple culture steps that may include co-culture with feeder cells, and exhibit large variability in erythroid cell yields between hPSC l
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Dick, Emily, Divya Rajamohan, Jonathon Ronksley, and Chris Denning. "Evaluating the utility of cardiomyocytes from human pluripotent stem cells for drug screening." Biochemical Society Transactions 38, no. 4 (2010): 1037–45. http://dx.doi.org/10.1042/bst0381037.

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Functional cardiomyocytes can now be derived routinely from hPSCs (human pluripotent stem cells), which collectively include embryonic and induced pluripotent stem cells. This technology presents new opportunities to develop pharmacologically relevant in vitro screens to detect cardiotoxicity, with a view to improving patient safety while reducing the economic burden to industry arising from high drug attrition rates. In the present article, we consider the need for human cardiomyocytes in drug-screening campaigns and review the strategies used to differentiate hPSCs towards the cardiac lineag
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Dissertations / Theses on the topic "HPSC"

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SCARFÒ, REBECCA. "Precise characterization of hemogenic endothelial cells during human hematopoietic development." Doctoral thesis, Università Vita-Salute San Raffaele, 2022. http://hdl.handle.net/20.500.11768/128259.

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During embryonic development, blood cells emerge from a subset of specialized endothelial cells, named hemogenic endothelium (HE), via a process known as endothelial-to-hematopoietic transition (EHT). HE represents a heterogeneous population found in various anatomical sites, including the yolk sac (YS) and the aorta-gonad-mesonephros (AGM). It comprises cells that differ in developmental potential, thus defining distinct hematopoietic programs. Despite the endothelial descendancy of blood cells is well established, the identity of HE is still debated. A more thorough characterization of HE is
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O'Brien, Laura. "Mitochondrial biogenesis and electrical properties of hPSC-derived motor neurons." VCU Scholars Compass, 2015. http://scholarscompass.vcu.edu/etd/3804.

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Human pluripotent stem cells (hPSCs), including human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) hold great promise in the fields of drug development and regenerative medicine. If iPSCs reprogrammed from patient cells replicate what is seen in vivo they may be used as a model of disease. A process that is disrupted in many neurodegenerative diseases is mitochondrial biogenesis. One of these diseases is amyotrophic lateral sclerosis (ALS), which is characterized by loss of motor neurons in the brain and spinal cord. Differentiation of hPSCs into motor neurons offers
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Frith, Thomas J. R. "Delineating the signals in anterior-posterior patterning of hPSC derived neural crest cells." Thesis, University of Sheffield, 2017. http://etheses.whiterose.ac.uk/19471/.

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Li, Ling. "Effects of pancreatic secretory stress proteins (SSP) on human pancreatic stellate cells (hPSC)." [S.l. : s.n.], 2007. http://nbn-resolving.de/urn:nbn:de:bsz:289-vts-58568.

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Heinrich, Amely [Verfasser]. "Aktivierung von Akt (Proteinkinase B) in humanen pankreatischen Sternzellen (hPSC) durch Pankreaskarzinomzellen / Amely Heinrich." Ulm : Universität Ulm, 2018. http://d-nb.info/1154486842/34.

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Bargehr, Johannes. "The role of human embryonic stem cell-derived epicardium in myocardial graft development." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/276112.

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Vargas, Valderrama Alejandra. "Différenciation des cellules souches pluripotentes humaines en cellules endothéliales et cellules hématopoïétiques via une population du type hémangioblastique Efficient hPSC differentiation into endothelial and hematopoietic cells via a hemangioblast-like population." Thesis, université Paris-Saclay, 2020. http://www.theses.fr/2020UPASQ021.

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Les cellules endothéliales (CE) et les cellules hématopoïétiques dérivées des cellules souches pluripotentes humaines (CSPh) sont un outil prometteur pour l'ingénierie tissulaire, la thérapie cellulaire et pour la découverte de nouveaux médicaments. Les CE assurent la formation des vaisseaux sanguins, tandis que les cellules hématopoïétiques matures sont impliquées dans le transport de l'oxygène, l'hémostase et la réponse immunitaire entre autres. Dans cette étude, nous avons différencié des CSPh en une population bipotente de type hémangioblastique pour générer des populations pures de ces de
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Frank, Elie. "Modélisation du Syndrome d'Alström à partir de cellules souches pluripotentes humaines pour l'identification de cibles moléculaires d'intérêt thérapeutique." Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPASQ041.

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Le syndrome d'Alström (SA) est une maladie monogénique récessive multi-systémique, caractérisée notamment par une perte de l'audition et de la vue, une obésité, un diabète de type 2, une cardiomyopathie et une insuffisance hépatique et rénale progressive. Les symptômes affectant la vision se développent dès les premières semaines après la naissance et mènent progressivement à une perte totale de la vue. À l'heure actuelle, aucun traitement ne permet de soigner cette maladie et seules des solutions permettant de réduire les effets des symptômes peuvent être proposées.L'objet de la thèse est de
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Sánchez, Brito Wendy Cecilia. "Estudio comparativo del control de la liberación del valproato de magnesio en matrices hidrofílicas de HPC y HPMC." Tesis de maestría, Universidad Autónoma del Estado de México, 2019. http://hdl.handle.net/20.500.11799/104992.

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Es un proyecto vinculado con algunos procesos realizados en la industria farmacéutica<br>En la última mitad de presente siglo se ha tratado de prolongar el efecto de un principio activo o fármaco a través de la modulación de su liberación desde la forma farmacéutica. En las formas farmacéuticas sólidas, este tipo de regulación ha sido posible principalmentea través del uso de matrices sólidas, incluyendo dentro de ellas a las matrices hidrofílicas. Dos éteres de la celulosa empleados en la formulación de matrices hidrofílicas, hidroxipropilmetilcelulosa (HPMC) e hidroxipropilcelulosa (HP
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Bakirdere, Sezgin. "Speciation Studies Using Hplc-icp-ms And Hplc-es-ms." Phd thesis, METU, 2009. http://etd.lib.metu.edu.tr/upload/3/12611391/index.pdf.

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Knowledge about selenium content of foods containing selenium species is very important in terms of both nutrition and toxicity. Bioavailability of selenium species for human body is different from each other. Hence, speciation of selenium is more important than total selenium determination. In the selenium speciation study, chicken breast samples, selenium supplement tablets and egg samples were analyzed for their selenium contents. In chicken breast study, chickens were randomly categorized into three groups including the control group (25 chickens), inorganic selenium fed group (25 chickens
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Books on the topic "HPSC"

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Bock, Hans Georg, Hoang Xuan Phu, Rolf Rannacher, and Johannes P. Schlöder, eds. Modeling, Simulation and Optimization of Complex Processes HPSC 2015. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-67168-0.

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Bock, Hans Georg, Xuan Phu Hoang, Rolf Rannacher, and Johannes P. Schlöder, eds. Modeling, Simulation and Optimization of Complex Processes - HPSC 2012. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-09063-4.

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Bock, Hans Georg, Willi Jäger, Ekaterina Kostina, and Hoang Xuan Phu, eds. Modeling, Simulation and Optimization of Complex Processes HPSC 2018. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-55240-4.

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Rehm, Werner. Innovative CFD Methoden für Studien zur Wasserstoff-Sicherheit mit High-Performance Supercomputing (HPSC): Weiterentwicklung, Validierung, und Performance Analyse. Shaker, 2001.

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McMaster, Marvin. HPLC. John Wiley & Sons, Ltd., 2006.

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Vonk, N., B. G. J. Baars, and H. Schaller. Fehlersuche in der HPLC / Troubleshooting in der HPLC. Birkhäuser Basel, 1990. http://dx.doi.org/10.1007/978-3-0348-5600-3.

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Great, Britain Department of Health and Social Services Northern Ireland Health and Personal Social Services Management Executive. HPSS management plan. [DHSS], 1996.

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Röpke, Werner. Der HPLC-Schrauber. Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527676927.

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Kromidas, Stavros, ed. The HPLC Expert. Wiley-VCH Verlag GmbH & Co. KGaA, 2016. http://dx.doi.org/10.1002/9783527677610.

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Pasch, Harald, and Bernd Trathnigg. HPLC of Polymers. Springer Berlin Heidelberg, 1999. http://dx.doi.org/10.1007/978-3-642-58265-3.

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Book chapters on the topic "HPSC"

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Weiss, Jeffrey N. "Treating Heart Failure with hPSC-CMs." In Stem Cell Surgery Trials in Heart Failure and Diabetes. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-78010-4_16.

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Bokanowski, O., E. Bourgeois, A. Désilles, and H. Zidani. "Global Optimization Approach for the Ascent Problem of Multi-stage Launchers." In Modeling, Simulation and Optimization of Complex Processes HPSC 2018. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-55240-4_1.

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Rehfeldt, Daniel, Yuji Shinano, and Thorsten Koch. "SCIP-Jack: An Exact High Performance Solver for Steiner Tree Problems in Graphs and Related Problems." In Modeling, Simulation and Optimization of Complex Processes HPSC 2018. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-55240-4_10.

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Tseng, Dong-Huei, Minh Q. Phan, and Richard W. Longman. "Physical Parameter Identification with Sensors or Actuators Spanning Multiple DOF’s." In Modeling, Simulation and Optimization of Complex Processes HPSC 2018. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-55240-4_11.

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Kurganov, Alexander, and Petr N. Vabishchevich. "Monotonization of a Family of Implicit Schemes for the Burgers Equation." In Modeling, Simulation and Optimization of Complex Processes HPSC 2018. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-55240-4_12.

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Ji, Xiaoqiang, and Richard W. Longman. "The Insensitivity of the Iterative Learning Control Inverse Problem to Initial Run When Stabilized by a New Stable Inverse." In Modeling, Simulation and Optimization of Complex Processes HPSC 2018. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-55240-4_13.

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Hoffmeister, Susanne, and Jörg Rambau. "Strategy Optimization in Sports via Markov Decision Problems." In Modeling, Simulation and Optimization of Complex Processes HPSC 2018. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-55240-4_14.

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Bastian, Peter, and Chaiyod Kamthorncharoen. "An Application of RASPEN to Discontinuous Galerkin Discretisation for Richards’ Equation in Porous Media Flow." In Modeling, Simulation and Optimization of Complex Processes HPSC 2018. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-55240-4_15.

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Wang, Bowen, and Richard W. Longman. "On the Development of Batch Stable Inverse Indirect Adaptive Control of Systems with Unstable Discrete-Time Inverse." In Modeling, Simulation and Optimization of Complex Processes HPSC 2018. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-55240-4_16.

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Klein, Ole. "An Improved Conjugate Gradients Method for Quasi-linear Bayesian Inverse Problems, Tested on an Example from Hydrogeology." In Modeling, Simulation and Optimization of Complex Processes HPSC 2018. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-55240-4_17.

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Conference papers on the topic "HPSC"

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"Committee Members HPSC 2021 BigDataSecurity/HPSC/IDS 2021." In 2021 7th IEEE Intl Conference on Big Data Security on Cloud (BigDataSecurity), IEEE Intl Conference on High Performance and Smart Computing, (HPSC) and IEEE Intl Conference on Intelligent Data and Security (IDS). IEEE, 2021. http://dx.doi.org/10.1109/bigdatasecurityhpscids52275.2021.00009.

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"Message from the Program Chairs HPSC 2021 BigDataSecurity/HPSC/IDS 2021." In 2021 7th IEEE Intl Conference on Big Data Security on Cloud (BigDataSecurity), IEEE Intl Conference on High Performance and Smart Computing, (HPSC) and IEEE Intl Conference on Intelligent Data and Security (IDS). IEEE, 2021. http://dx.doi.org/10.1109/bigdatasecurityhpscids52275.2021.00008.

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"Committee Members (HPSC 2023)." In 2023 IEEE 9th Intl Conference on Big Data Security on Cloud (BigDataSecurity), IEEE Intl Conference on High Performance and Smart Computing, (HPSC) and IEEE Intl Conference on Intelligent Data and Security (IDS). IEEE, 2023. http://dx.doi.org/10.1109/bigdatasecurity-hpsc-ids58521.2023.00009.

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"HPSC 2019 Committee Members." In 2019 IEEE 5th Intl Conference on Big Data Security on Cloud (BigDataSecurity), IEEE Intl Conference on High Performance and Smart Computing, (HPSC) and IEEE Intl Conference on Intelligent Data and Security (IDS). IEEE, 2019. http://dx.doi.org/10.1109/bigdatasecurity-hpsc-ids.2019.00009.

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"HPSC 2018 Conference Organization." In 2018 IEEE 4th International Conference on Big Data Security on Cloud (BigDataSecurity), IEEE International Conference on High Performance and Smart Computing, (HPSC) and IEEE International Conference on Intelligent Data and Security (IDS). IEEE, 2018. http://dx.doi.org/10.1109/bds/hpsc/ids18.2018.00010.

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"HPSC 2018 Program Committee." In 2018 IEEE 4th International Conference on Big Data Security on Cloud (BigDataSecurity), IEEE International Conference on High Performance and Smart Computing, (HPSC) and IEEE International Conference on Intelligent Data and Security (IDS). IEEE, 2018. http://dx.doi.org/10.1109/bds/hpsc/ids18.2018.00011.

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"Conference Organization; HPSC 2024." In 2024 IEEE 10th IEEE International Conference on High Performance and Smart Computing (HPSC). IEEE, 2024. http://dx.doi.org/10.1109/hpsc62738.2024.00006.

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"BigDataSecurity/HPSC/IDS 2020 TOC." In 2020 IEEE 6th Intl Conference on Big Data Security on Cloud (BigDataSecurity), IEEE Intl Conference on High Performance and Smart Computing, (HPSC) and IEEE Intl Conference on Intelligent Data and Security (IDS). IEEE, 2020. http://dx.doi.org/10.1109/bigdatasecurity-hpsc-ids49724.2020.00004.

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"BigDataSecurity/HPSC/IDS 2020 Opinion." In 2020 IEEE 6th Intl Conference on Big Data Security on Cloud (BigDataSecurity), IEEE Intl Conference on High Performance and Smart Computing, (HPSC) and IEEE Intl Conference on Intelligent Data and Security (IDS). IEEE, 2020. http://dx.doi.org/10.1109/bigdatasecurity-hpsc-ids49724.2020.00005.

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"BigDataSecurity/HPSC/IDS 2020 Opinion." In 2020 IEEE 6th Intl Conference on Big Data Security on Cloud (BigDataSecurity), IEEE Intl Conference on High Performance and Smart Computing, (HPSC) and IEEE Intl Conference on Intelligent Data and Security (IDS). IEEE, 2020. http://dx.doi.org/10.1109/bigdatasecurity-hpsc-ids49724.2020.00008.

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Reports on the topic "HPSC"

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Dongarra, Jack. High Performance Computing (HPC) Challenge (HPCC) Benchmark Suite Development. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada436281.

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Annunziato, Dom. High-Performance Liquid Chromatography Analysis of Psilocybin-Containing Mushrooms: Key Considerations and Insights. GenTech Scientific LLC, 2023. http://dx.doi.org/10.61073/gentech.hplc.top.5.

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HPLC analysis of psilocybin-containing mushrooms is a complex process that requires careful attention to detail. In this scientific summary, Doma Nunzio1, MagicMyco C.S.O., offers insight and new answers to some old questions about these magic fungi. Based on his dedicated research and progress in the field, here are his top five things to keep in mind when conducting HPLC-UV analysis in reverse phase ‘RP Mode’ for psilocybin-containing mushrooms.
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Monroe, Laura Marie. HPC Visualization. Office of Scientific and Technical Information (OSTI), 2015. http://dx.doi.org/10.2172/1179065.

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Manno, Dominic A. HPC Utilities. Office of Scientific and Technical Information (OSTI), 2012. http://dx.doi.org/10.2172/1049322.

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Fultz, Michael W. Acquisition of HPLC-Mass Spectrometer. Defense Technical Information Center, 2015. http://dx.doi.org/10.21236/ad1001112.

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Hazen, Damian, and Jason Hick. GPFS HPSS Integration: Implementation Experience. Office of Scientific and Technical Information (OSTI), 2008. http://dx.doi.org/10.2172/938421.

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Sulfredge, C., and Ronald Lee. HPAC Validation against NRC Documentation. Office of Scientific and Technical Information (OSTI), 2020. http://dx.doi.org/10.2172/1760110.

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Joyce, Christine, and Deidre Mountain. Optimization of Liposomal Encapsulation Efficiency. University of Tennessee Health Science Center, 2021. http://dx.doi.org/10.21007/com.lsp.2018.0002.

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Introduction: My project was a continuation of the Vascular Research Lab’s (VRL) ongoing research at the University of Tennessee Medical Center Knoxville (UTMCK) aimed at optimizing liposomal encapsulation efficiency of small interfering RNA (siRNA) which can be used to silence genes to prevent a variety of disease pathologies. Methods: Assay siRNA loading capacity of liposomes based on lipid concentration Development of a method for liposome purification: HPLC &amp; HiTRAP Column Results &amp; Conclusion: siRNA loading capacity Higher lipid:siRNA resulted in increased encapsulation efficiency
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Dennig, Yasmin. SNL HPC 2018. Office of Scientific and Technical Information (OSTI), 2018. http://dx.doi.org/10.2172/1476162.

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Gaspar, Andrew James. Rust in HPC. Office of Scientific and Technical Information (OSTI), 2018. http://dx.doi.org/10.2172/1485376.

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