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Journal articles on the topic 'HPV infections'

Author: Grafiati

Published: 24 May 2025

Last updated: 31 July 2025

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1

Gudenkauf, Franciska J., and Aaron P. Thrift. "Racial/Ethnic Differences in Cancers Attributable to Preventable Infectious Agents in Texas, 2015." Public Health Reports 135, no. 6 (2020): 805–12. http://dx.doi.org/10.1177/0033354920954497.

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Objective The International Agency for Research on Cancer has classified 13 infectious agents as carcinogenic or probably carcinogenic to humans. We aimed to estimate the percentage (ie, population-attributable fraction) and number of incident cancer cases in Texas in 2015 that were attributable to oncogenic infections, overall and by race/ethnicity. Methods We calculated population-attributable fractions for cancers attributable to human papillomavirus (HPV), Helicobacter pylori, hepatitis C virus (HCV), hepatitis B virus (HBV), and human herpesvirus 8 (HHV-8) infections using prevalence esti

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Bigoni, Jérôme, Rosa Catarino, Caroline Benski, et al. "High Burden of Human Papillomavirus Infection in Madagascar: Comparison With Other Sexually Transmitted Infections." Infectious Diseases: Research and Treatment 11 (January 1, 2018): 117863371775268. http://dx.doi.org/10.1177/1178633717752686.

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Background: In Madagascar, human papillomavirus (HPV), human immunodeficiency virus (HIV), and hepatitis B virus (HBV) infection, as well as syphilis share common risk factors but seem to differ in their prevalence. We measured and compared their prevalence in the country. Methods: The data used in this study came from the Saint Damien Health Centre in Ambanja, Madagascar. The tests used for disease detection were the Alere Determine, Virucheck, rapid plasma reagin, and S-DRY self-HPV samples for HIV infection, HBV infection, syphilis, and HPV infection, respectively. Results: In men and women

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Pavone, Giuliana, Andrea Marino, Viviana Fisicaro, et al. "Entangled Connections: HIV and HPV Interplay in Cervical Cancer—A Comprehensive Review." International Journal of Molecular Sciences 25, no. 19 (2024): 10358. http://dx.doi.org/10.3390/ijms251910358.

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Cervical cancer (CC) remains a prevalent malignancy and a significant global public health concern, primarily driven by persistent human papillomavirus (HPV) infections. The infectious nature of HPV underscores the preventability of CC through vaccination and screening programs. In addition to HPV, factors such as age, parity, smoking, hormonal contraceptives, and HIV co-infection elevate the risk of CC. HIV-associated immunodeficiency exacerbates susceptibility to infections and cancers, making CC a defining condition for acquired immune deficiency syndrome (AIDS) and one of the most commonly

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Pujantell, Maria, Eva Riveira-Muñoz, Edurne García-Vidal, et al. "ADAR1 Function Regulates Innate Immune Activation and Susceptibility to Viral Infections." Proceedings 50, no. 1 (2020): 34. http://dx.doi.org/10.3390/proceedings2020050034.

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Viral infection induces innate intracellular antiviral defenses, aimed at restricting virus replication and spread. Therefore, understanding the role and function of innate immune modulators can help to establish novel strategies for viral control. Here, we explore the role of ADAR1 as a regulator of the HIV, HCV, and HPV infections, both in vitro and in vivo, in a genetic association study. Depletion of ADAR1 induced innate immune activation, observed by a significant increase in IFNB1 mRNA and CXCL10 expression. Further characterization of ADAR1 knockdown also showed upregulation of the RNA

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Viscidi, Raphael P., Brad Snyder, Susan Cu-Uvin, et al. "Human Papillomavirus Capsid Antibody Response to Natural Infection and Risk of Subsequent HPV Infection in HIV-Positive and HIV-Negative Women." Cancer Epidemiology, Biomarkers & Prevention 14, no. 1 (2005): 283–88. http://dx.doi.org/10.1158/1055-9965.283.14.1.

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Abstract The association between seropositivity to virus-like particles (VLP) of human papillomavirus (HPV) types 16, 18, 31, 35, or 45 and subsequent cervical HPV infection was examined in 829 women with HIV and 413 risk-matched HIV-negative women. We found no statistically significant differences between HPV-seropositive and HPV-seronegative women in the risk of a new infection with the homologous HPV type, with the exception of a reduced risk of HPV 45 infections 4.5 years beyond the baseline serology measurement in HIV-positive women [hazard ratio, 0.21; 95% confidence interval (CI), 0.05-

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Odutola, Michael Kolawole, Elima Jedy-Agba, Emmanuel Oga, et al. "Cancers Attributable to Infectious Agents in Nigeria: 2012-2014." Journal of Global Oncology 2, no. 3_suppl (2016): 77s—78s. http://dx.doi.org/10.1200/jgo.2016.004317.

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Abstract 60 Background: Infections by certain viruses, bacteria, and parasites have been identified as risk factors for some cancers. In 2008, there were 12.7 million new cancer cases worldwide. About 2 million of these new cases were attributable to infections, which represent 16.1% of new cancer cases. The majority of these cancers occurred in less-developed regions of the world, where the Population Attributable Fraction (PAF) was estimated to be 23%. We carried out this study to evaluate the numbers of cancers in Nigeria from 2012-2014 that are attributable to infections using data from Po

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Adebamowo, Sally N., Toyosi Olawande, Ayotunde Famooto, et al. "Risk, Persistence and Multiplicity of HPV Infections among HIV Negative and HIV Positive Nigerian Women." Journal of Global Oncology 2, no. 3_suppl (2016): 38s—39s. http://dx.doi.org/10.1200/jgo.2016.003830.

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Abstract 64 Background: The incidence, prevalence, persistence, and multiplicity of high-risk HPV infection is different between HIV positive and HIV negative women. We examined the association between HIV, prevalent HPV, and persistent HPV infections among women in a prospective cohort in Nigeria. Methods: We enrolled women presenting at cervical cancer screening programs in Abuja, Nigeria, between 2012 and 2014 and collected information on their demographic characteristics, risk factors of HPV infection, and cervical exfoliated cells samples at baseline, 6 month and 12 month follow-up visits

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Yao, Pang, Iona Millwood, Christiana Kartsonaki, et al. "Sero-prevalence of 19 infectious pathogens and associated factors among middle-aged and elderly Chinese adults: a cross-sectional study." BMJ Open 12, no. 5 (2022): e058353. http://dx.doi.org/10.1136/bmjopen-2021-058353.

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ObjectivesTo systematically assess the sero-prevalence and associated factors of major infectious pathogens in China, where there are high incidence rates of certain infection-related cancers.DesignCross-sectional study.Setting10 (5 urban, 5 rural) geographically diverse areas in China.ParticipantsA subcohort of 2000 participants from the China Kadoorie Biobank.Primary measuresSero-prevalence of 19 pathogens using a custom-designed multiplex serology panel and associated factors.ResultsOf the 19 pathogens investigated, the mean number of sero-positive pathogens was 9.4 (SD 1.7), with 24.4% of

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Adler, David H., Melissa Wallace, Thola Bennie, et al. "Cervical Dysplasia and High-Risk Human Papillomavirus Infections among HIV-Infected and HIV-Uninfected Adolescent Females in South Africa." Infectious Diseases in Obstetrics and Gynecology 2014 (2014): 1–6. http://dx.doi.org/10.1155/2014/498048.

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Background.HIV-infected adolescents may be at higher risk for high-grade cervical lesions than HIV-uninfected adolescents. The purpose of this study was to compare the prevalence of high-risk HPV (HR-HPV) infections and Pap smear abnormalities between these two groups.Methods.In this cross-sectional study, we compared the HPV DNA and Pap smear results between 35 HIV-infected and 50 HIV-uninfected adolescents in order to determine the prevalence of HR-HPV genotypes and cervical cytological abnormalities. Comparisons were made using Pearsonχ2and independent-samplest-tests analyses, and associati

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Rollo, Francesca, Alessandra Latini, Maria Benevolo, et al. "Concurrent and Concordant Anal and Oral Human PapillomaVirus Infections Are Not Associated with Sexual Behavior in At-Risk Males." Pathogens 10, no. 10 (2021): 1254. http://dx.doi.org/10.3390/pathogens10101254.

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Men who have sex with men (MSM) harbor the highest prevalence of anal and oral Human Papillomavirus (HPV) infection, particularly if HIV-infected. We investigated anal and oral HPV infections in HIV-infected and HIV-uninfected MSM, to assess concurrent (HPV detected at both sites, irrespective of the genotypes), and concordant infections (same genotype[s] detected at both sites). Matched anal and oral samples from 161 MSM (85 HIV-infected, and 76 HIV-uninfected) were tested with the Linear Array. Determinants of concurrent and concordant infections were evaluated using logistic regression. Ana

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Adler, David H., Melissa Wallace, Thola Bennie, et al. "Cumulative Impact of HIV and Multiple Concurrent Human Papillomavirus Infections on the Risk of Cervical Dysplasia." Advances in Virology 2016 (2016): 1–5. http://dx.doi.org/10.1155/2016/7310894.

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Infection with HIV is known to increase the risk of cervical cancer. In addition, evidence suggests that concurrent infection with multiple human papillomavirus (HPV) genotypes increases the risk of cervical dysplasia more than infection with a single HPV genotype. However, the impact of the combination of HIV coinfection and presence of multiple concurrent HPV infections on the risk of cervical dysplasia is uncertain. We compared the results of HPV testing and Pap smears between HIV-infected and HIV-uninfected young women to assess the cumulative impact of these two conditions. We found that

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Adebamowo, Sally N., Ayotunde Famooto, Eileen O. Dareng, et al. "Clearance of Type-Specific, Low-Risk, and High-Risk Cervical Human Papillomavirus Infections in HIV-Negative and HIV-Positive Women." Journal of Global Oncology, no. 4 (December 2018): JGO.17.00129. http://dx.doi.org/10.1200/jgo.17.00129.

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Purpose There is a dearth of data on clearance of cervical human papillomavirus (HPV) infection among women in West Africa. We examined the clearance of low-risk (lr) and high-risk (hr) cervical HPV infections, and the factors associated with these measures in HIV-negative and HIV-positive women. Methods We studied 630 Nigerian women involved in a study of HPV infection using short polymerase chain reaction fragment-10 assay and line probe assay-25. Research nurses used a cervical brush to collect samples of exfoliated cervical cells from all the study participants. Cox proportional hazards mo

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Rodrigues, Luana Lorena Silva, José Henrique Pilotto, Katrini Guidolini Martinelli, et al. "Diversity of Anal HPV and Non-HPV Sexually Transmitted Infections and Concordance with Genital Infections in HIV-Infected and HIV-Uninfected Women in the Tapajós Region, Amazon, Brazil." Viruses 15, no. 6 (2023): 1328. http://dx.doi.org/10.3390/v15061328.

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The aim of this study was to classify the diversity of anal HPV and non-HPV sexually transmitted infections (STIs) and compare the concordance between anal and genital infections in HIV-infected and uninfected women living in the Tapajós region, Amazon, Brazil. A cross-sectional study was performed with 112 HIV-uninfected and 41 HIV-infected nonindigenous women. Anal and cervical scrapings were collected and analyzed for HPV, Chlamydia trachomatis (CT), Neisseria gonorrheae (NG), Trichomonas vaginalis (TV), Mycoplasma genitalium (MG), and Human alphaherpesvirus 2 (HSV-2). The Kappa test evalua

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Fracella, Matteo, Giuseppe Oliveto, Piergiorgio Roberto, et al. "The Epidemiology of Anal Human Papillomavirus (HPV) in HIV-Positive and HIV-Negative Women and Men: A Ten-Year Retrospective Observational Study in Rome (Italy)." Pathogens 13, no. 2 (2024): 163. http://dx.doi.org/10.3390/pathogens13020163.

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Human papillomaviruses (HPVs) commonly infect the anogenital mucosa; most infections are transient, but a fraction of those caused by high-risk (HR) types persist and may lead to anogenital cancer. The epidemiology of HPV genotypes in anal infections in groups at different risk for anal cancer has not been well described in Italy. This retrospective study reports the results of HPV DNA testing and complete genotyping performed on anal swabs from 691 female and male patients attending proctology clinics in Rome during 2012–2021; one-third had repeated testing. Cumulative HPV positivity in 1212

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Okoye, Jude Ogechukwu, Chukwudi Amaechi Ofodile, Oluwaseun Kelechi Adeleke, and Okechi Obioma. "Prevalence of high-risk HPV genotypes in sub-Saharan Africa according to HIV status: a 20-year systematic review." Epidemiology and Health 43 (May 25, 2021): e2021039. http://dx.doi.org/10.4178/epih.e2021039.

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OBJECTIVES: This review assessed the rate of high-risk human papillomavirus (HPV) infection among women living in sub-Saharan Africa. It also determined the prevalence of high-risk HPV (hrHPV) among human immunodeficiency virus (HIV) seropositive (HIV+) and seronegative (HIV-) women in sub-Saharan Africa, pre-2010 and post-2010.METHODS: In this systematic review, Google Scholar, PubMed Central, and Embase were searched to identify cohort and case-control studies that investigated the relationship between HIV and HPV infection. The database searches yielded 17 studies published between 1999 and

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Beliakov, Ilia, Maria Senina, Yuriy Tyulenev, Elena Novoselova, Viktor Surovtsev, and Alexander Guschin. "The Prevalence of High Carcinogenic Risk of HPV Genotypes among HIV-Positive and HIV-Negative MSM from Russia." Canadian Journal of Infectious Diseases and Medical Microbiology 2021 (May 31, 2021): 1–6. http://dx.doi.org/10.1155/2021/6641888.

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Objective. Men who have sex with men (MSM) have a high risk of lifelong anal cancer caused by high-risk human papillomavirus (HR HPV) infections. The aim of this study was to investigate the prevalence of anal canal HR HPV infection among men who have sex with men (MSM) with and without HIV infection in Moscow (Russia). We evaluated associations of some HIV coinfections (HSV and CMV) and HPV distribution among MSM with and without HIV infection. Methods. Two groups of HIV-positive (n = 60) and HIV-negative (n = 60) MSM were evaluated in the study. Fourteen high-risk (HR) HPV types, HSV1/2, and

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Mehdi Poor, Nargis Khatoon Hossein, Laila Mohamed Jasim Ali AlDabal, Safia Bashiri, et al. "Syphilis and Beyond: A Comprehensive Analysis of Associated Infections and Comorbidities in a Five-Year Retrospective Study in the United Arab Emirates (2018-2022)." International Journal of Sexually Transmitted Diseases 1, no. 2 (2024): 19–28. http://dx.doi.org/10.14302/issn.2994-6743.ijstd-24-5006.

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Objectives This study explores the clinical characteristics, associated infections, and management outcomes of syphilis within a specific population over the years 2018 to 2022. With a focus on the frequency, clinical manifestations, and co-infections of syphilis, the research addresses a critical gap in understanding the nuanced dynamics of this sexually transmitted infection and its impact on public health. Methods The study employs a retrospective analysis of data collected from 2018 to 2022, utilizing three key serological tests (Syphilis AB, RPR/VDRL, and TPHA) to characterize syphilis in

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Wang, Qian, Xiaomeng Ma, Xiaosong Zhang, et al. "Human papillomavirus infection and associated factors for cervical intraepithelial neoplasia in women living with HIV in China: a cross-sectional study." Sexually Transmitted Infections 95, no. 2 (2018): 140–44. http://dx.doi.org/10.1136/sextrans-2018-053636.

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ObjectiveWomen living with HIV (WLHIV) face disproportionately higher risks of acquiring human papillomavirus (HPV) compared with HIV negative counterparts. We aimed to investigate the prevalence of HPV in WLHIV in Chinese hospital setting and identify associated factors to the progression of late-stage cervical intraepithelial neoplasia (CIN2+) in this population.MethodThis retrospective study collected data from 183 WLHIV on antiretroviral treatment (ART), based on reproductive health questionnaires. Gynaecological examination results including serum (for HIV viral load, CD4 T-cell count, he

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Cardoso Marques, Marcos Paulo, Amanda Chaves Pinto, Leila Cristina Soares, Jacyara Maria Brito Macedo, Debora Fontenelle dos Santos, and Marco Aurelio Pinho Oliveira. "Differences in HPV infection and HPV-related lesions between the cervix and anus in hiv-positive women." Revista de Ciências Médicas e Biológicas 20, no. 2 (2021): 229–34. http://dx.doi.org/10.9771/cmbio.v20i2.43354.

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Introduction: the prevalence of cervical and anal human papillomavirus (HPV) infection in women infected with human immunodeficiency virus (HIV) is high. However, little is known about the differences in the susceptibility of these infections and related lesions. The aim of this study was to describe the association between the prevalence of cervical and anal HPV infection and HPV-related lesions in HIV-positive women. Methods: this study included 88 HIV-positive women attending an outpatient clinic in a university hospital. Ectocervical, endocervical, and anal samples were collected for colpo

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Sweet, Kristen, Claire Bosire, Busola Sanusi, et al. "Prevalence, incidence, and distribution of human papillomavirus types in female sex workers in Kenya." International Journal of STD & AIDS 31, no. 2 (2020): 109–18. http://dx.doi.org/10.1177/0956462419884454.

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Female sex workers (FSWs) have a notably high risk of acquiring human papillomavirus (HPV) infections. Relatively few studies address the type-specific prevalence and incidence of HPV among FSWs in sub-Saharan Africa. FSWs (n = 348) attending the Korogocho clinic in Nairobi, Kenya participated from August 2009 to March 2011. HPV DNA was detected using the SPF10-LiPA25 PCR assay. Baseline prevalence of HPV infection and cervical dysplasia were calculated, stratified by HIV-serostatus. Incidence rate (IR) of infection was calculated as number of new infections from baseline over person-months am

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Syrjänen, S. "Human Papillomavirus Infection and Its Association with HIV." Advances in Dental Research 23, no. 1 (2011): 84–89. http://dx.doi.org/10.1177/0022034511399914.

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Human papillomavirus (HPV) can infect oral mucosa, causing asymptomatic infection or warty lesions. Several case-control studies have confirmed HPV as an independent risk factor for squamous cell carcinoma. HPV-related cancers seem to have better prognoses and different risk factors than do HPV-negative ones. HIV-infected patients are known to be at increased risk for persistent genital and anal high-risk HPV infections and intraepithelial neoplasm. Since the era of highly active antiretroviral therapy, the prevalence and persistence of warty lesions in oral mucosa have increased. Oral squamou

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Ablanedo-Terrazas, Yuria, Karla Romero-Mora, María Gómez-Palacio, et al. "Prevalence and risk factors for oral human papillomavirus infection in Mexican HIV-infected men." Salud Pública de México 60, no. 6, nov-dic (2018): 653. http://dx.doi.org/10.21149/9834.

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Objective. To determine the prevalence and risk factors for oral high-risk human papillomavirus (HR-HPV) infection in human immunodeficiency virus (HIV)-infected men. Materials and methods. Consecutive male outpatients with HIV-infection were enrolled. Demographic and behavioral risk data were obtained. Anal swabs and oral rinses were tested for HR-HPV DNA. Oral, pharyngeal and video laryngoscopy examinations were performed for detection of lesions. Results. The prevalence of HR-HPV oral infection was 9.3% (subtypes other than HR HPV 16/18 predominated). The prevalence of anal HR-HPV infection

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Feriyawati, Lita, Dwi Rita Anggraini, and Tetty Aman Nasution. "Co-Infection of Human Papillomavirus with Mycoplasma Hominis/Ureaplasma Urealyticum Among Female Sex Workers in Medan, Indonesia." Open Access Macedonian Journal of Medical Sciences 7, no. 20 (2019): 3425–28. http://dx.doi.org/10.3889/oamjms.2019.438.

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Human papillomavirus (HPV) infection is one of the most prevalent sexually transmitted diseases among women aged < 35 years worldwide. Recent studies have suggested that the vaginal microenvironment influenced by bacterial infection poses for high-risk human papillomavirus (hrHPV) infection and cervical carcinogenesis. Female sex workers (FSWs) are a population susceptible to acquire Human Immunodeficiency Virus (HIV) and sexually transmitted infections (STIs), as well as transmitting the virus to others. The aim of this study is to evaluate the relationship between Mycoplasma/Ureaplasma in

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Kustova, M. A. "PAPILLOMAVIRUS AND GENITAL CO-INFECTIONS IN PREGNANT HIV-NEGATIVE AND HIV-POSITIVE WOMEN." Health and Ecology Issues, no. 2 (June 28, 2012): 77–84. http://dx.doi.org/10.51523/2708-6011.2012-9-2-14.

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Objective: to study the features of human papillomavirus (HPV) infection, combined with the co-infections of the urogenital tract in HIV-positive and HIV-negative pregnant women. Material and methods. The object of the study was 144 pregnant women examined for the presence of HPV DNA and herpes viruses in cervical scrapes. The screening for chlamydial infection was conducted by ELISA method, the culture method was used to detect genital ureaplasma infection, the diagnosis of genital candidiasis was carried out by microscopy. Results. The features of HPV infection were studied in the combinatio

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Kim, Jinhee, Moonsik Kim, and Ji Young Park. "Evaluation of the characteristics of multiple human papillomavirus (HPV) infections identified using the BD Onclarity HPV assay and comparison with those of single HPV infection." Journal of Pathology and Translational Medicine 56, no. 5 (2022): 289–93. http://dx.doi.org/10.4132/jptm.2022.08.02.

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Background: Human papillomavirus (HPV) infection is a major cause of cervical cancer and associated precursor lesions. Multiple HPV genotype infections have been reported. However, their clinicopathological characteristics still remain elusive.Methods: For this study, 814 consecutive patients who had undergone colposcopy and HPV genotyping test using BD Onclarity HPV assay were retrospectively selected. Clinicopathological parameters of multiple HPV infections were compared with those of single HPV infection.Results: Multiple HPV infections were found in 110 out of 814 cases (13.5%). Multiple

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Ogliastro, Matilde, Allegra Ferrari, Laura Sticchi, et al. "Effectiveness of a Counseling Intervention to Increase Vaccination Uptake among Men Who Have Sex with Men during the Mpox Outbreak." Vaccines 12, no. 7 (2024): 751. http://dx.doi.org/10.3390/vaccines12070751.

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Men who have sex with men (MSM) are disproportionately impacted by sexually transmitted infections (STIs), including HIV and those preventable through vaccination such as mpox, HPV, HAV, and HBV. A retrospective cohort study was conducted to evaluate the effectiveness of counseling provided during mpox vaccination on the uptake of other recommended vaccines (HPV, HAV, and HBV) and to identify associated factors. Relevant covariates such as nationality, age, HIV status, and use of PrEP were retrieved from electronic medical records. Vaccination status data were retrieved from the regional vacci

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Meireles, Sheila Itamara Ferreira do Couto, Sônia Maria Fonseca de Andrade, Cristiano Luiz Horta de Lima Júnior, and Mario Cezar Pires. "Epidermodysplasia verruciformis in a young man with HIV since birth - case report." Anais Brasileiros de Dermatologia 88, no. 6 suppl 1 (2013): 190–92. http://dx.doi.org/10.1590/abd1806-4841.20132328.

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Epidermodysplasia Verruciformis is a genodermatosis characterized by susceptibility to infection by specific HPV types (HPV 3/10 and beta-HPVs). It is considered to be the first model in human carcinogenesis induced by HPV. In this report we present a rare case of Epidermodysplasia Verruciformis associated with vertical transmission of HIV. Although most patients with HIV present infections by HPV virus, the frequency of Epidermodysplasia Verruciformis is no greater in patients with HIV because in EV there is a deficiency of specific cellular immunity to infection by some types of HPV, called

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Chikandiwa, Admire, Pedro T. Pisa, Matthew F. Chersich, Etienne E. Muller, Philippe Mayaud, and Sinead Delany-Moretlwe. "Oropharyngeal HPV infection: prevalence and sampling methods among HIV-infected men in South Africa." International Journal of STD & AIDS 29, no. 8 (2018): 776–80. http://dx.doi.org/10.1177/0956462418755882.

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Worldwide, 96,000 cases of oropharyngeal cancer (OPC) occurred in 2012. Human papillomavirus (HPV) is a risk factor for OPC. Data on oropharyngeal HPV infection are limited. There is no consensus on the best sampling method for detecting the infection. We describe the prevalence of oropharyngeal HPV infection among HIV-infected men and compare the performance of oral rinses and swabs in detecting oropharyngeal HPV infection. Paired oral rinses and swabs for 181 men were tested for HPV DNA using the Roche Linear Array. Performance was determined by the number of infections detected and the perc

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Shakya, Sunila, Solveig Thingulstad, Unni Syversen, et al. "Prevalence of Sexually Transmitted Infections among Married Women in Rural Nepal." Infectious Diseases in Obstetrics and Gynecology 2018 (August 26, 2018): 1–9. http://dx.doi.org/10.1155/2018/4980396.

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Introduction. We have previously determined the prevalence of human papillomavirus (HPV) infection among women in rural Nepal. In the current study, we also wanted to examine the prevalence of and risk factors for other sexually transmitted infections (STIs) in the same population. Methods. Population-based study of nonpregnant women ≥ 15 years who were married or had a history of marriage in the past, residing in five rural villages in Nepal. Data on sociodemographic characteristics, reproductive history, and genitourinary symptoms were collected, and a gynecological examination was conducted

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Mulherkar, Tania H., Daniel Joseph Gómez, Grace Sandel, and Pooja Jain. "Co-Infection and Cancer: Host–Pathogen Interaction between Dendritic Cells and HIV-1, HTLV-1, and Other Oncogenic Viruses." Viruses 14, no. 9 (2022): 2037. http://dx.doi.org/10.3390/v14092037.

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Dendritic cells (DCs) function as a link between innate and adaptive immune responses. Retroviruses HIV-1 and HTLV-1 modulate DCs to their advantage and utilize them to propagate infection. Coinfection of HTLV-1 and HIV-1 has implications for cancer malignancies. Both viruses initially infect DCs and propagate the infection to CD4+ T cells through cell-to-cell transmission using mechanisms including the formation of virologic synapses, viral biofilms, and conduits. These retroviruses are both neurotrophic with neurovirulence determinants. The neuropathogenesis of HIV-1 and HTLV-1 results in ne

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Yuan, Defu, Shanshan Liu, Yangyang Liu, et al. "HPV Infection Profiles among People Living with HIV and HPV Vaccine Acceptance among Individuals with Different HIV Infection Statuses in China: A Systematic Meta-Analysis." Vaccines 11, no. 10 (2023): 1614. http://dx.doi.org/10.3390/vaccines11101614.

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To understand the HPV infection profiles among Chinese HIV/AIDS patients and the HPV vaccine acceptance among unvaccinated Chinese people with different HIV infection statuses after the HPV vaccine launch in China, this study searched Web of Science, PubMed, Cochrane Library, Embase, Scopus, CNKI, WANFANG, SinoMed, and VIP databases up to 23 June 2023, according to the registered protocol (CRD42023449913). A total of 58 studies were included. The results showed that the HPV infection rate among Chinese HIV/AIDS patients was 52.54% (95% CI: 42.11–62.86%) and higher in males than in females (74.

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Makhorina, T. V., K. E. Boeva, G. V. Malyshkina, and A. V. Semenov. "MECHANISMS OF EVACUATION OF THE HUMAN PAPILLOMA VIRUS FROM THE IMMUNE RESPONSE IN HIV-INFECTED PEOPLE." Laboratornaya i klinicheskaya meditsina. Farmatsiya, no. 8 (2023): 46–59. http://dx.doi.org/10.14489/lcmp.2023.02.pp.046-059.

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Human papillomavirus (HPV) infections and related diseases are a major problem worldwide. The immune response to human papillomavirus infection in patients with human immunodeficiency virus (HIV) deserves special attention. HPV serves as an etiological agent and biological carcinogen for lesions and cancers associated with HPV. Currently, many possible mechanisms of escape of viruses from factors of innate and adaptive immunity are known. Despite the large amount of accumulated knowledge about the course of HIV and papillomavirus infections, early diagnosis and timely treatment of co-infected

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Emmanuel Eilu, Charity Basaza Mulenga, John Charles Okiria, Charles Drago Kato, and Ismail Abiola Adebayo. "Type-specific HPV incidence and clinical spectrum of lesions induced by high-risk oncogenic HPV types among study participants in Eastern Uganda." International Journal of Science and Technology Research Archive 4, no. 1 (2023): 156–65. http://dx.doi.org/10.53771/ijstra.2023.4.1.0025.

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Different studies show that high-risk HPV genotypes are the main etiological agents for cervical cancer development and cancer-related deaths in women worldwide. In Uganda, cervical malignancies due to human papillomavirus (HPV) are predominant among sexually active women. However, data on the incidence and clinical spectrum of lesions associated with high-risk HPV infection is inadequate. The current study was aimed to determine incidence and clinical spectrum of lesions induced by high-risk oncogenic HPV types among study participants in Eastern Uganda. We piloted a prospective follow-up stu

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Karathanasi, Vassiliki, Malamatenia Bourazani, Christina Orfanou, et al. "Common oral viral infections." ACTA MICROBIOLOGICA HELLENICA 59, no. 1 (2014): 29–37. https://doi.org/10.5281/zenodo.10012687.

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Oral cavity as being an "open gate" of the human body comprises an appropriate field for the establishment of varying infections. Oral viral infections can be either primary and localized or secondary to systematic infection. The most common oral viral infections are caused by herpes viruses, enteroviruses and human papilloma viruses. Among herpes viruses, herpes simplex virus 1(HSV-1), vericella-zoster virus (VZV) and Epstein-Barr virus (EBV) affect the oral cavity more frequently. HSV-1 and VZV appear in the form of vesicles that break leaving secondary painful ulcerations. EBV within the de

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Coutlée, François, Alexandra de Pokomandy, and Eduardo L. Franco. "Epidemiology, natural history and risk factors for anal intraepithelial neoplasia." Sexual Health 9, no. 6 (2012): 547. http://dx.doi.org/10.1071/sh11167.

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Studies conducted in HIV-seropositive individuals have enhanced our understanding of the natural history of anal intraepithelial neoplasia (AIN) and of factors predictive of progression to high-grade AIN, the immediate precursor to anal cancer. AIN is frequently detected in HIV-seropositive individuals. Factors that increase the risk for AIN include HIV infection, low current or nadir blood CD4+ cell counts, receptive anal intercourse, oncogenic human papillomavirus (HPV) infection, persistent anal HPV infection, multiple HPV type infections and high anal HPV viral load. This review confirms t

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Jovanovic, Marina, Djordjije Karadaglic, Zoran Golusin, Silvija Brkic, and Mirjana Poljacki. "Experimental vaccines for sexually transmitted infections." Medical review 62, no. 1-2 (2009): 42–48. http://dx.doi.org/10.2298/mpns0902042j.

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Introduction. Sexually transmitted infections (STIs) are major global public health problems. Present strategies for prevention have limitations. Vaccines are an attractive addition to the current prevention armamentarium because they provide durable protection and do not require repetitive adherence to be effective. Challenges for vaccination include induction and long-term maintaince of mucosal immune responses in the female genital tract. Vaccines: a realistic goal?. For the time being, US Centers for Disease Control and Prevention have recommended only hepatitis and HPV immunization to be

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Oyervides-Muñoz, Mariel A., Antonio A. Pérez-Maya, Celia N. Sánchez-Domínguez, et al. "Multiple HPV Infections and Viral Load Association in Persistent Cervical Lesions in Mexican Women." Viruses 12, no. 4 (2020): 380. http://dx.doi.org/10.3390/v12040380.

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Persistent high-risk human papillomavirus (HR-HPV) infections play a major role in the development of invasive cervical cancer (CC), and screening for such infections is in many countries the primary method of detecting and preventing CC. HPV typing can be used for triage and risk stratification of women with atypical squamous cells of undetermined significance (ASC-US)/low-grade cervical lesions (LSIL), though the current clinical practice in Mexico is to diagnose CC or its preceding conditions mainly via histology and HR-HPV detection. Additional information regarding these HPV infections, s

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Sambo, Margherita, Alessandra Bailoni, Federico Mariani, et al. "Prevalence, Incidence and Predictors of Anal HPV Infection and HPV-Related Squamous Intraepithelial Lesions in a Cohort of People Living with HIV." Diagnostics 15, no. 2 (2025): 198. https://doi.org/10.3390/diagnostics15020198.

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Background: Anal HPV infection can cause squamous intraepithelial lesions (SILs), which are precursors of anal squamous cell carcinoma (SCC). The early detection of HPV infections and improvement of effective screening programmes are, therefore, essential to prevent progression from pre-cancerous lesions to SCC, especially in people living with HIV (PLWH), who represent a population at higher risk of HPV infection and associated lesions. Among prevention strategies, HPV vaccination is relevant too, but its efficacy in persons already infected by HPV is still debated. Methods: This is a retrosp

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Singh, Kavita N., Sheetal Achale, and Vineeta Ghanghoriya. "A study on HPV mRNA test and colposcopy in HIV positive women for early detection of cervical intraepithelial lesions." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 6, no. 6 (2017): 2522. http://dx.doi.org/10.18203/2320-1770.ijrcog20172344.

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Background: Sexually transmitted infections (STIs) have a profound impact on sexual and reproductive health worldwide. At any point of time, globally more than 290 million women suffer from HPV infection, one of the most common STIs. There are only few studies from India reported regarding the prevalence of HPV and cervical abnormalities among HIV-positive women. This study was carried out to estimate the prevalence of HPV and other genital tract infection in HIV positive women and correlate HPV mRNA test and colposcopic findings with cyto-histopathology in HIV positive women who are not on an

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Salazar, Katrina L., Haijun Steve Zhou, Jiaqiong Xu, et al. "Multiple Human Papilloma Virus Infections and Their Impact on the Development of High-Risk Cervical Lesions." Acta Cytologica 59, no. 5 (2015): 391–98. http://dx.doi.org/10.1159/000442512.

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Objective: Individuals are often infected with multiple genotypes of human papillomavirus (HPV) simultaneously, but the role these infections play in the development of cervical disease is not well established. This study aimed to determine the association of multiple HPV infections with high-risk cervical lesions (hrCLs). Study Design: HPV genotyping was performed on 798 SurePath specimens collected between December 1, 2009, and April 30, 2011. The cases were classified as hrCL (n = 90) or non-hrCL (n = 708) based on cytology diagnoses. The association between hrCL and HPV infection patterns

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Pauciullo, Silvia, Daniele Colombo, Verdiana Zulian, et al. "Association of Methylated DNA Markers with High-Risk HPV Infections in Oral Site and Precancer Anal Lesions in HIV-Positive MSM." Biomedicines 12, no. 8 (2024): 1838. http://dx.doi.org/10.3390/biomedicines12081838.

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Background: Human papillomavirus (HPV) infection is linked to several cancers, including anal and oral cancers. The incidence of anal cancer is particularly high among HIV-positive men who have sex with men (MSM). DNA methylation markers have shown promise as biomarkers for identifying precancerous lesions and cancer in HPV-infected individuals. The aim of this study was to investigate the correlation of DNA methylation with HPV infection in oral samples and the correlation of DNA methylation with lesion degree in the anal samples of HIV-positive MSM. Methods: This study investigated DNA methy

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MARTINELLI, M., F. MAZZA, E. R. FRATI, et al. "HPV genotypes detected in the oropharyngeal mucosa of HIV-infected men who have sex with men in Northern Italy." Epidemiology and Infection 144, no. 12 (2016): 2641–47. http://dx.doi.org/10.1017/s0950268816001163.

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SUMMARYThe aim of this study was to investigate the epidemiological profile of HPV oropharyngeal infections in HIV-infected men who have sex with men. A total of 135 subjects were enrolled at the L. Sacco University Hospital (Milan, Italy) to evaluate their HPV oropharyngeal infection status at baseline and at a follow-up visit at least 12 months later. HPV DNA was detected from oropharyngeal swabs using an in-house nested PCR that amplifies a segment of the L1 gene. The PCR products were then sequenced and genotyped. A greater percentage of high-risk genotypes was identified compared to low-r

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Maueia, Cremildo, Alltalents Murahwa, Alice Manjate, et al. "Identification of the Human Papillomavirus Genotypes, According to the Human Immunodeficiency Virus Status in a Cohort of Women from Maputo, Mozambique." Viruses 14, no. 1 (2021): 24. http://dx.doi.org/10.3390/v14010024.

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Background: Human papillomavirus (HPV) infection is now a well-established cause of cervical cancer and other anogenital cancers. An association between human immunodeficiency virus (HIV) infection and higher HPV incidence and prevalence are commonly reported. This study was conducted to demonstrate HPV prevalence, genotypes and its characteristics, according to the HIV status in women from Maputo in Mozambique. Methods: A total of 233 participants with ages ranging from fourteen to forty-five were included. Cervical samples were collected, DNA extracted, and HPV genotyping was performed using

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P, Das. "Semen Infection Associated Male Infertility and Role of Assisted Reproductive Techniques: A Review." Virology & Immunology Journal 6, no. 3 (2022): 1–9. http://dx.doi.org/10.23880/vij-16000297.

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Recent research has revealed that pathogens in the semen and in the genital tract play a significant role in male infertility. The infection of viruses like Human Immunodeficiency Virus (HIV), Hepatitis B virus (HBV), Hepatitis C virus (HCV), Human Papilloma Virus (HPV), Herpes-Simplex Virus (HSV), and Human Cytomegalovirus (HCMV) may have a significant impact on male infertility. These infections may lead to temporary or permanent infertility, hormonal impairment, testicular malfunction, or abnormal spermatogenesis. This review is looking into the mechanism of viral infections and their effec

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Tounkara, Fatoumata Korika, Ibrahima Téguété, Fernand A. Guédou, et al. "Human papillomavirus genotype distribution and factors associated among female sex workers in West Africa." PLOS ONE 15, no. 11 (2020): e0242711. http://dx.doi.org/10.1371/journal.pone.0242711.

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Objectives This study aimed to: (1) Estimate HPV prevalence and genotype distribution among female sex workers (FSWs) in Mali and Benin as well as the prevalence of multiple HPV type infections in this group, and (2) Identify potential risk factors associated with high-risk (HR) HPV infections. Methods We analyzed baseline data of 665 FSWs aged ≥ 18 years recruited during a prospective cohort of cervical cancer screening in Cotonou (Benin) and Bamako (Mali) from 2017 to 2018. The Linear Array HPV genotyping test was used to identify HPV genotypes. Descriptive statistics and multivariate log-bi

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Alam, Samina, Sreejata Chatterjee, Sa Do Kang, et al. "Anti-Retroviral Protease Inhibitors Regulate Human Papillomavirus 16 Infection of Primary Oral and Cervical Epithelium." Cancers 12, no. 9 (2020): 2664. http://dx.doi.org/10.3390/cancers12092664.

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Epidemiology studies suggest that Human Immunodeficiency Virus (HIV)-infected patients on highly active anti-retroviral therapy (HAART) may be at increased risk of acquiring opportunistic Human Papillomavirus (HPV) infections and developing oral and cervical cancers. Effective HAART usage has improved survival but increased the risk for HPV-associated cancers. In this manuscript, we report that Protease Inhibitors (PI) treatment of three-dimensional tissues derived from primary human gingiva and cervical epithelial cells compromised cell-cell junctions within stratified epithelium and enhanced

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Adebamowo, Sally Nneoma, Michael Kolawole Odutola, Ayo Famooto, et al. "Incidence, persistence and determinants of human papillomavirus: A prospective cohort study of 10,000 HIV-negative Nigerian women." Journal of Clinical Oncology 35, no. 15_suppl (2017): 1510. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.1510.

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1510 Background: Cervical cancer is the second commonest cancer in Africa. Persistent High-risk HPV (HRHPV) infection is a necessary cause but little is known about the persistence and associated risk factors of HRHPV infection in African women. The aim of this study was to determine risk factors and incidence of HPV infection in Nigerian women. Methods: ACCME is a multicenter prospective cohort study of host germline, cervical somatic and HRHPV genomics, epigenomics, and vaginal microenvironment; and their association with HPV. From February/2014 to January/2016, 10,000 HIV-negative women wer

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Olafimihan, Ayobami Gbenga, Vaishali Deenadayalan, Praise Fawehinmi, and Shweta Gupta. "Impact of HIV-HPV co-infection on inpatient penile cancer outcomes." Journal of Clinical Oncology 42, no. 4_suppl (2024): 6. http://dx.doi.org/10.1200/jco.2024.42.4_suppl.6.

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6 Background: HPV (human papillomavirus) and HIV (Human Immunodeﬁciency Virus) are risk factors for Penile cancer (PC); HIV-HPV co-infection heightens the risk of anogenital dysplasia (PMID: 19706632, 19082746, 35630489). However, there is paucity of data on the impact of HIV-HPV co-infections on PC outcomes. We evaluated the characteristics, outcomes, and healthcare utilization of patients with PC with and without HIV-HPV co-infection (HHC) from a national sample. Methods: Healthcare Cost and Utilization Project-Nationwide Inpatient Sample database was queried to identify all PC patients with

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Muwonga Tukisadila, Jonathan, Ralph-Sydney Mboumba Bouassa, Serge Tonen-Wolyec, Hugues Loemba, Jeremie Muwonga, and Laurent Belec. "Syndemic Synergy of HPV, HIV, and HSV-2 for Oncogenic HPV Replication in Female Sex Workers." Tropical Medicine and Infectious Disease 10, no. 6 (2025): 157. https://doi.org/10.3390/tropicalmed10060157.

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Background: Female sex workers (FSWs) in sub-Saharan Africa bear a disproportionate burden of sexually transmitted infections, including HIV, high-risk HPV (HR-HPV), and herpes simplex virus type 2 (HSV-2). This study evaluated possible association between HR-HPV, HIV, and HSV-2 among FSWs in the Democratic Republic of the Congo. Methods: A cross-sectional study was conducted among 432 FSWs (mean age, 28.1 years) recruited via respondent-driven sampling. Genital self-sampling using the V-Veil UP2™ device was performed, followed by HPV genotyping and quantification by multiplex PCR, and HSV-2 D

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Kosz, f. Katarzyna, Martyna Zielińska, Natalia Zarankiewicz, Aleksandra Kuchnicka, and Bogumiła Ciseł. "Relationship between HPV and HIV. Prevalence, molecular mechanisms and screening of HPV among HIV infected women." Journal of Education, Health and Sport 10, no. 7 (2020): 127–37. https://doi.org/10.12775/JEHS.2020.10.07.013.

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<strong>Kosz Katarzyna, </strong><strong>Zielińska Martyna, Zarankiewicz Natalia, Kuchnicka Aleksandra, Ciseł Bogumiła</strong><strong>. </strong><strong>Relationship between HPV and HIV. Prevalence, molecular mechanisms and screening of HPV among HIV infected women</strong><strong>. Journal of Education, Health and Sport. 2020;10(7):127-137. eISSN 2391-8306. DOI </strong><strong>http://dx.doi.org/10.12775/JEHS.2020.10.07.013</strong> <strong>https://apcz.umk.pl/czasopisma/index.php/JEHS/article/view/JEHS.2020.10.07.013</strong> <strong>https://zenodo.org/record/3951124</strong>    

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