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1

Ogliastro, Matilde, Allegra Ferrari, Laura Sticchi, et al. "Effectiveness of a Counseling Intervention to Increase Vaccination Uptake among Men Who Have Sex with Men during the Mpox Outbreak." Vaccines 12, no. 7 (2024): 751. http://dx.doi.org/10.3390/vaccines12070751.

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Men who have sex with men (MSM) are disproportionately impacted by sexually transmitted infections (STIs), including HIV and those preventable through vaccination such as mpox, HPV, HAV, and HBV. A retrospective cohort study was conducted to evaluate the effectiveness of counseling provided during mpox vaccination on the uptake of other recommended vaccines (HPV, HAV, and HBV) and to identify associated factors. Relevant covariates such as nationality, age, HIV status, and use of PrEP were retrieved from electronic medical records. Vaccination status data were retrieved from the regional vacci
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Francies, Flavia Zita, and Zodwa Dlamini. "Aberrant Splicing Events and Epigenetics in Viral Oncogenomics: Current Therapeutic Strategies." Cells 10, no. 2 (2021): 239. http://dx.doi.org/10.3390/cells10020239.

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Global cancer incidence and mortality are on the rise. Although cancer is fundamentally a non-communicable disease, a large number of cancers are known to have a viral aetiology. A high burden of infectious agents (Human immunodeficiency virus (HIV), human papillomavirus (HPV), hepatitis B virus (HBV)) in certain Sub-Saharan African countries drives the rates of certain cancers. About one-third of all cancers in Africa are attributed to infection. Seven viruses have been identified with carcinogenic characteristics, namely the HPV, HBV, Hepatitis C virus (HCV), Epstein–Barr virus (EBV), Human
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Bigoni, Jérôme, Rosa Catarino, Caroline Benski, et al. "High Burden of Human Papillomavirus Infection in Madagascar: Comparison With Other Sexually Transmitted Infections." Infectious Diseases: Research and Treatment 11 (January 1, 2018): 117863371775268. http://dx.doi.org/10.1177/1178633717752686.

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Background: In Madagascar, human papillomavirus (HPV), human immunodeficiency virus (HIV), and hepatitis B virus (HBV) infection, as well as syphilis share common risk factors but seem to differ in their prevalence. We measured and compared their prevalence in the country. Methods: The data used in this study came from the Saint Damien Health Centre in Ambanja, Madagascar. The tests used for disease detection were the Alere Determine, Virucheck, rapid plasma reagin, and S-DRY self-HPV samples for HIV infection, HBV infection, syphilis, and HPV infection, respectively. Results: In men and women
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Gudenkauf, Franciska J., and Aaron P. Thrift. "Racial/Ethnic Differences in Cancers Attributable to Preventable Infectious Agents in Texas, 2015." Public Health Reports 135, no. 6 (2020): 805–12. http://dx.doi.org/10.1177/0033354920954497.

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Objective The International Agency for Research on Cancer has classified 13 infectious agents as carcinogenic or probably carcinogenic to humans. We aimed to estimate the percentage (ie, population-attributable fraction) and number of incident cancer cases in Texas in 2015 that were attributable to oncogenic infections, overall and by race/ethnicity. Methods We calculated population-attributable fractions for cancers attributable to human papillomavirus (HPV), Helicobacter pylori, hepatitis C virus (HCV), hepatitis B virus (HBV), and human herpesvirus 8 (HHV-8) infections using prevalence esti
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Rojas, Livisu Pajares, and Claudia Machicado Rivero. "Abstract 883: Glutaminases expression and viral infection as potential prognostic factors in cervical, head and neck and liver cancers." Cancer Research 83, no. 7_Supplement (2023): 883. http://dx.doi.org/10.1158/1538-7445.am2023-883.

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Abstract Human Papilloma virus (HPV)-associated Cervical squamous cell carcinoma (CESC-HPV(+)), HPV-associated Head and Neck squamous cell carcinoma (HNSCC-HPV(+)), and Hepatitis Virus B/C (HBV/HCV)-associated Liver hepatocellular carcinoma (LIHC-HBV(+)/LIHC-HCV(+)) present metabolic changes during viral transformation to adjust energy demands of transformed cells. Glutamine is used as an important energy and carbon source by cancer cells through its degradation (glutaminolysis). This latter is regulated by Glutaminases 1 and 2 (GLS1/GLS2) that convert glutamine in glutamate. GLS1/2 expression
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Yao, Pang, Iona Millwood, Christiana Kartsonaki, et al. "Sero-prevalence of 19 infectious pathogens and associated factors among middle-aged and elderly Chinese adults: a cross-sectional study." BMJ Open 12, no. 5 (2022): e058353. http://dx.doi.org/10.1136/bmjopen-2021-058353.

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ObjectivesTo systematically assess the sero-prevalence and associated factors of major infectious pathogens in China, where there are high incidence rates of certain infection-related cancers.DesignCross-sectional study.Setting10 (5 urban, 5 rural) geographically diverse areas in China.ParticipantsA subcohort of 2000 participants from the China Kadoorie Biobank.Primary measuresSero-prevalence of 19 pathogens using a custom-designed multiplex serology panel and associated factors.ResultsOf the 19 pathogens investigated, the mean number of sero-positive pathogens was 9.4 (SD 1.7), with 24.4% of
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Pujantell, Maria, Eva Riveira-Muñoz, Edurne García-Vidal, et al. "ADAR1 Function Regulates Innate Immune Activation and Susceptibility to Viral Infections." Proceedings 50, no. 1 (2020): 34. http://dx.doi.org/10.3390/proceedings2020050034.

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Viral infection induces innate intracellular antiviral defenses, aimed at restricting virus replication and spread. Therefore, understanding the role and function of innate immune modulators can help to establish novel strategies for viral control. Here, we explore the role of ADAR1 as a regulator of the HIV, HCV, and HPV infections, both in vitro and in vivo, in a genetic association study. Depletion of ADAR1 induced innate immune activation, observed by a significant increase in IFNB1 mRNA and CXCL10 expression. Further characterization of ADAR1 knockdown also showed upregulation of the RNA
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Qədir qızı Əbilova, Rübayə, Gülnarə Alışa qızı Cəfərova, and Hafiz Maarif oğlu Osmanov. "The role of viruses and bacteria in the development of cancer." NATURE AND SCIENCE 11, no. 06 (2021): 5–10. http://dx.doi.org/10.36719/2707-1146/11/5-10.

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Recently, there have been some scientific studies proving the role of viruses and bacteria in the development of cancer. Among them are eighteen types of pathogens (Helicobacter pylori, hepatitis B virus (HBV), hepatitis C virus (HCV), Opisthorchis viverrini, Clonorchis sinensis, Schistosoma haematobium, human papillomavirus (HPV), Barr (EBV) virus, Ephthia virus-human cell 1 (HTLV-1), human herpes virus type 8 (HHV-8) and human immunodeficiency virus type 1 (HIV-1), belong to group 1 carcinogens. Further study of the role of viruses and bacteria in the development of cancer is of great import
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9

Osagie, Esosa, Paul Akhigbe, Nosakhare Idemudia, et al. "Human Papillomavirus, Human Immunodeficiency Virus, and Oral Microbiota Interplay in Nigerian Youth (HOMINY): A Prospective Cohort Study Protocol." BMJ Open 15, no. 2 (2025): e091017. https://doi.org/10.1136/bmjopen-2024-091017.

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IntroductionPersistent oral infections with high-risk human papillomavirus (HR-HPV) are a potential cause of most oropharyngeal cancers (OPCs). Oral HR-HPV infection and persistence are significantly higher in people living with HIV (PLWH). Most data on oral HR-HPV in PLWH come from developed countries or adult cohorts. This study aims to investigate oral HR-HPV susceptibility and persistence among children and adolescents living with HIV (CALHIV) and to understand the roles of perinatal HIV exposure, infection, antiretroviral treatment, and the oral microbiome.Methods and analysisThis prospec
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10

King, Christy M., James S. Johnston, Kene Ofili, et al. "Human Papillomavirus Types 2, 27, and 57 Identified in Plantar Verrucae from HIV-Positive and HIV-Negative Individuals." Journal of the American Podiatric Medical Association 104, no. 2 (2014): 141–46. http://dx.doi.org/10.7547/0003-0538-104.2.141.

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Background Although an increased prevalence of plantar verrucae has been associated with human immunodeficiency virus (HIV) infection, human papillomavirus (HPV) typing studies have not been published about this patient population. We sought to determine the prevalence of HPV types in plantar verrucae of HIV-positive (HIV+) and HIV-negative (HIV–) individuals. Methods Thirty-nine plantar verruca lesions in 17 individuals were examined. Nine participants were HIV+ and eight were HIV–. Detection of HPV was performed by polymerase chain reaction using two sets of primers: MY09/MY11. The type of H
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Okoye, Jude Ogechukwu, Chukwudi Amaechi Ofodile, Oluwaseun Kelechi Adeleke, and Okechi Obioma. "Prevalence of high-risk HPV genotypes in sub-Saharan Africa according to HIV status: a 20-year systematic review." Epidemiology and Health 43 (May 25, 2021): e2021039. http://dx.doi.org/10.4178/epih.e2021039.

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OBJECTIVES: This review assessed the rate of high-risk human papillomavirus (HPV) infection among women living in sub-Saharan Africa. It also determined the prevalence of high-risk HPV (hrHPV) among human immunodeficiency virus (HIV) seropositive (HIV+) and seronegative (HIV-) women in sub-Saharan Africa, pre-2010 and post-2010.METHODS: In this systematic review, Google Scholar, PubMed Central, and Embase were searched to identify cohort and case-control studies that investigated the relationship between HIV and HPV infection. The database searches yielded 17 studies published between 1999 and
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Toft, Lars, Martin Tolstrup, Merete Storgaard, Lars Østergaard, and Ole S. Søgaard. "Vaccination against oncogenic human papillomavirus infection in HIV-infected populations: review of current status and future perspectives." Sexual Health 11, no. 6 (2014): 511. http://dx.doi.org/10.1071/sh14015.

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Background Men and women with HIV infection are at increased risk of developing cancers associated with human papillomavirus (HPV). The two licensed prophylactic HPV vaccines protect against de novo infection with HPV-16 and HPV-18, which cause the majority of HPV-associated cancers. Currently, no vaccine efficacy data are available for persons with HIV infection. Nevertheless, some countries have implemented specific HPV vaccination recommendations for HIV-positive populations. To specifically recommend prophylactic HPV vaccination in people with HIV, the vaccines must be safe and immunogenic
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13

Teslova, O. A. "CO-INFECTION WITH HUMAN PAPILLOMA VIRUS OF HIV-POSITIVE WOMEN (literature review)." Health and Ecology Issues, no. 3 (September 28, 2012): 44–49. http://dx.doi.org/10.51523/2708-6011.2012-9-3-9.

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Aim. To study the prevalence of genital HPV infection in HIV-positive women and their mutual influence, their manifestations and outcomes in co-infected HPV- and HIV-positive patients, including the period during their pregnancy and after the childbirth according to scientific publications. Material and methods. Present-day national and international research works on female HPV and HIV co-infection were reviewed. Results. The article presents the data on genital HPV-infection prevalence and characterization of HPV types in HIV-positive patients, the relation of HPV-infection with immune disor
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Naucler, Pontus, Flora Mabota da Costa, Joao Leopoldo da Costa, Otto Ljungberg, Antonio Bugalho, and Joakim Dillner. "Human papillomavirus type-specific risk of cervical cancer in a population with high human immunodeficiency virus prevalence: case–control study." Journal of General Virology 92, no. 12 (2011): 2784–91. http://dx.doi.org/10.1099/vir.0.034298-0.

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There are limited data on human papillomavirus (HPV) type-specific cervical cancer risk among human immunodeficiency virus (HIV)-positive women. Previous studies have suggested that HPV 16 would be relatively less important as a causative agent among HIV-positive compared with HIV-negative women. This study investigates HPV type-specific cervical cancer risk in a population in which HIV is endemic. At the Central Hospital, Maputo, Mozambique, 221 cervical cancer cases and 203 hospital-based controls were consecutively enrolled. HPV typing from cervical samples, HIV testing and recording of soc
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15

Viscidi, Raphael P., Brad Snyder, Susan Cu-Uvin, et al. "Human Papillomavirus Capsid Antibody Response to Natural Infection and Risk of Subsequent HPV Infection in HIV-Positive and HIV-Negative Women." Cancer Epidemiology, Biomarkers & Prevention 14, no. 1 (2005): 283–88. http://dx.doi.org/10.1158/1055-9965.283.14.1.

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Abstract The association between seropositivity to virus-like particles (VLP) of human papillomavirus (HPV) types 16, 18, 31, 35, or 45 and subsequent cervical HPV infection was examined in 829 women with HIV and 413 risk-matched HIV-negative women. We found no statistically significant differences between HPV-seropositive and HPV-seronegative women in the risk of a new infection with the homologous HPV type, with the exception of a reduced risk of HPV 45 infections 4.5 years beyond the baseline serology measurement in HIV-positive women [hazard ratio, 0.21; 95% confidence interval (CI), 0.05-
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16

Maueia, Cremildo, Alltalents Murahwa, Alice Manjate, et al. "Identification of the Human Papillomavirus Genotypes, According to the Human Immunodeficiency Virus Status in a Cohort of Women from Maputo, Mozambique." Viruses 14, no. 1 (2021): 24. http://dx.doi.org/10.3390/v14010024.

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Background: Human papillomavirus (HPV) infection is now a well-established cause of cervical cancer and other anogenital cancers. An association between human immunodeficiency virus (HIV) infection and higher HPV incidence and prevalence are commonly reported. This study was conducted to demonstrate HPV prevalence, genotypes and its characteristics, according to the HIV status in women from Maputo in Mozambique. Methods: A total of 233 participants with ages ranging from fourteen to forty-five were included. Cervical samples were collected, DNA extracted, and HPV genotyping was performed using
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Pérez-González, Alexandre, Edward Cachay, Antonio Ocampo, and Eva Poveda. "Update on the Epidemiological Features and Clinical Implications of Human Papillomavirus Infection (HPV) and Human Immunodeficiency Virus (HIV) Coinfection." Microorganisms 10, no. 5 (2022): 1047. http://dx.doi.org/10.3390/microorganisms10051047.

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Human papillomavirus (HPV) infection is the most common sexually transmitted infection (STI) worldwide. Although most HPV infections will spontaneously resolve, a considerable proportion of them will persist, increasing the risk of anogenital dysplasia, especially within certain populations, such as patients infected with human immunodeficiency virus (HIV). Furthermore, high-risk oncogenic HPV types (HR-HPV) are the main cause of cervix and other anogenital cancers, such as cancer of the vagina, vulva, penis, or anus. HIV and HPV coinfection is common among people living with HIV (PLWH) but di
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Olafimihan, Ayobami Gbenga, Vaishali Deenadayalan, Praise Fawehinmi, and Shweta Gupta. "Impact of HIV-HPV co-infection on inpatient penile cancer outcomes." Journal of Clinical Oncology 42, no. 4_suppl (2024): 6. http://dx.doi.org/10.1200/jco.2024.42.4_suppl.6.

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6 Background: HPV (human papillomavirus) and HIV (Human Immunodeficiency Virus) are risk factors for Penile cancer (PC); HIV-HPV co-infection heightens the risk of anogenital dysplasia (PMID: 19706632, 19082746, 35630489). However, there is paucity of data on the impact of HIV-HPV co-infections on PC outcomes. We evaluated the characteristics, outcomes, and healthcare utilization of patients with PC with and without HIV-HPV co-infection (HHC) from a national sample. Methods: Healthcare Cost and Utilization Project-Nationwide Inpatient Sample database was queried to identify all PC patients with
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Amirian, E. Susan, Elizabeth Y. Chiao, Kirk T. Hill, Deborah Marquez-Do та Michael E. Scheurer. "2. Preliminary findings from a pilot study on the effects of interferon-α treatment on human papillomavirus infection in HIV and hepatitis C virus co-infected men". Sexual Health 10, № 6 (2013): 570. http://dx.doi.org/10.1071/shv10n6ab2.

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Background Human papillomavirus (HPV) has been aetiologically linked with several different cancers. A'few older studies have evaluated the effects of interferon-α (IFN-α) treatment on HPV infection and HPV-related dysplasia. However, findings from these studies may not be generalisable to the more recent formulations of IFN-α used to treat hepatitis C virus (HCV) infection. Methods: The purpose of this small pilot study was to assess whether treatment for HCV, by pegylated rather than standard IFN-α, was associated with presence or distribution of the types of HPV found in the oral, penile, a
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Mulherkar, Tania H., Daniel Joseph Gómez, Grace Sandel, and Pooja Jain. "Co-Infection and Cancer: Host–Pathogen Interaction between Dendritic Cells and HIV-1, HTLV-1, and Other Oncogenic Viruses." Viruses 14, no. 9 (2022): 2037. http://dx.doi.org/10.3390/v14092037.

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Dendritic cells (DCs) function as a link between innate and adaptive immune responses. Retroviruses HIV-1 and HTLV-1 modulate DCs to their advantage and utilize them to propagate infection. Coinfection of HTLV-1 and HIV-1 has implications for cancer malignancies. Both viruses initially infect DCs and propagate the infection to CD4+ T cells through cell-to-cell transmission using mechanisms including the formation of virologic synapses, viral biofilms, and conduits. These retroviruses are both neurotrophic with neurovirulence determinants. The neuropathogenesis of HIV-1 and HTLV-1 results in ne
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Omenge, Elkanah, Yan Tong, Philip Tonui, et al. "Comparison of HPV detection in HIV-infected and HIV-uninfected Kenyan women with or without cervical dysplasia." Journal of Clinical Oncology 37, no. 15_suppl (2019): e17015-e17015. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e17015.

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e17015 Background: Cervical cancer, a malignancy caused by human papillomavirus (HPV) infection, is the most common malignancy in women living in sub-Saharan African countries including Kenya. HIV co-infection accelerates the natural course of cervical cancer. To determine the specific HPV type distribution in HIV-infected women compared to HIV-uninfected women, with and without evidence of cervical dysplasia. Methods: Demographic information, behavioral data, and a cervical swab were collected from women 18 and 45 years of age, HIV-infected or HIV-uninfected, who presented for cervical cancer
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Sweet, Kristen, Claire Bosire, Busola Sanusi, et al. "Prevalence, incidence, and distribution of human papillomavirus types in female sex workers in Kenya." International Journal of STD & AIDS 31, no. 2 (2020): 109–18. http://dx.doi.org/10.1177/0956462419884454.

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Female sex workers (FSWs) have a notably high risk of acquiring human papillomavirus (HPV) infections. Relatively few studies address the type-specific prevalence and incidence of HPV among FSWs in sub-Saharan Africa. FSWs (n = 348) attending the Korogocho clinic in Nairobi, Kenya participated from August 2009 to March 2011. HPV DNA was detected using the SPF10-LiPA25 PCR assay. Baseline prevalence of HPV infection and cervical dysplasia were calculated, stratified by HIV-serostatus. Incidence rate (IR) of infection was calculated as number of new infections from baseline over person-months am
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Zinzendorf, Nanga Yessé, Cablan Mian Asher, Zaba Flore Sandrine, et al. "Prevalence and Human Papillomavirus Genotypes Distribution among HIV-Positive and -Negative Young Women Aged 20 to 37-Years-Old with Cervical Cancer in Abidjan, Côte d'Ivoire." International Journal of Virology and AIDS 9, no. 1 (2022): 1–7. https://doi.org/10.23937/2469-567x/1510080.

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Introduction Human papilloma virus (HPV) infection is the major etiologic agent of cervical cancer. Both human papillomavirus (HPV) and human immunodeficiency virus (HIV) are classified as carcinogens. We describe the prevalence and distribution of HPV genotypes among HIV-positive and -negative women aged 20-37 years-old in Côte d'Ivoire. Material and methods Women were recruited among those who come to the gynecology department of the Military Hospital, Abidjan with a positive acetic acid test. HIV testing was performed on the basic of the Retrovirus Côte d'Ivoire testing algorithm. HPV DNA w
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Jalil, Emilia Moreira, Geraldo Duarte, Patrícia El Beitune, Renata Toscano Simões, Patrícia Pereira dos Santos Melli, and Silvana Maria Quintana. "High Prevalence of Human Papillomavirus Infection among Brazilian Pregnant Women with and without Human Immunodeficiency Virus Type 1." Obstetrics and Gynecology International 2009 (2009): 1–4. http://dx.doi.org/10.1155/2009/485423.

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Objective. To estimate HPV prevalence among pregnant women from Ribeirão Preto, Brazil, and the possible influence of HIV-1 infection on this prevalence.Methods. A cross-sectional study with 44 HIV-positive and 53 HIV-negative pregnant women was conducted. Cervicovaginal specimens were obtained from all women during gynecologic exam. HPV DNA, low and high risk HPV types, was detected using conventional PCR. Statistical analysis used Student'st-test, Mann-Whitney test, Fischer's Exact test, and prevalence ratios with 95% confidence interval.Results. HIV-positive pregnant women had higher propor
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Chuang, Eleanore, Melissa Agsalda, Xuemei Zhu, Brenda Hernandez, Cris Milne, and Bruce Shiramizu. "5. Detection of HIV DNA and HPV genotypes in the CD14+ fraction of anal cytology samples from HIV-positive human subjects." Sexual Health 10, no. 6 (2013): 572. http://dx.doi.org/10.1071/shv10n6ab5.

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Background HIV-seropositive patients have a higher prevalence of other viral infections, including HPV, even while on anti-retroviral therapy. Anal infection with high-risk HPV genotypes can lead to anal dysplasia, which can progress to anal cancer. HIV and HPV can be contracted via sexual transmission; however, the interaction between these two pathogens and effect on the immune system are poorly understood. Since CD14 cells have been implicated in disease progression in other HIV-associated diseases, the objective of this study was to characterise CD14 cells from anal cytology specimens. Met
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Mizushima, Daisuke, Misao Takano, Naokatsu Ando, et al. "Efficacy of Lactococcus lactis strain Plasma on clearance of anal HPV infection in men who have sex with men: A single-center, double-blinded, randomized placebo-controlled trial (CLEAR HPV study)." Medicine: Case Reports and Study Protocols 4, no. 10 (2023): e00300. http://dx.doi.org/10.1097/md9.0000000000000300.

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Background: Anal cancer is a human papillomavirus-related cancer; specifically, it is preceded by high-grade squamous intraepithelial lesions, which are less likely to regress spontaneously than low-grade intraepithelial lesions. Although most human papillomavirus (HPV) infections are thought to clear spontaneously, anal HPV infection persists, especially in people living with HIV. Preliminary results from a recent small randomized placebo-controlled trial of oral bacteriotherapy using a high dose of probiotics demonstrated clearance of anal high-risk HPV (hr-HPV) infection and lower onset of
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Gouton, Clémence D., Ifeoluwa O. Bejide, Oludayo O. Ope-ewe, et al. "HIV–HPV Co-Infection and Identification of Novel High-Risk HPV Among Women at Two Hospital Centers in Cotonou, Republic of Benin." Viruses 17, no. 5 (2025): 714. https://doi.org/10.3390/v17050714.

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Persistent high-risk human papillomaviruses (HR-HPVs) infection is the leading cause of cervical cancer. With over 200 circulating genotypes, HPV detection, management, and prevention remain challenging. In Benin, HPV prevalence and genotype distribution are largely unknown, and no national HPV vaccination program exists. This study investigates the prevalence, genotypic diversity, and risk factors of HIV–HPV co-infection among women in Cotonou, Benin. Cervical swabs were collected from 100 women living with HIV (WLWHIV) and 51 women without HIV (WWHIV) at two hospitals. DNA extraction and nes
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Cambrea, Simona Claudia, Mariana Aschie, Ghiulendan Resul, et al. "HPV and HIV Coinfection in Women from a Southeast Region of Romania—PICOPIV Study." Medicina 58, no. 6 (2022): 760. http://dx.doi.org/10.3390/medicina58060760.

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Background and Objectives: Romania faces one of the highest cervical cancer burdens in Europe though it is a preventable cancer through population screening by cytology and human papillomavirus (HPV) detection. Also, it has one of the highest incidences of human immunodeficiency virus (HIV) infection. HPV and HIV coinfection are frequently encountered. The aim of study was to establish the prevalence of HPV infection among HIV-positive women in Southeast Region of Romania, to genotype high risk HPV types -and to correlate the results with clinical data and cytological cervical lesions. Materia
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Omire, Agnes, Nancy L. M. Budambula, Leah Kirumbi, et al. "Cervical Dysplasia, Infection, and Phylogeny of Human Papillomavirus in HIV-Infected and HIV-Uninfected Women at a Reproductive Health Clinic in Nairobi, Kenya." BioMed Research International 2020 (June 17, 2020): 1–10. http://dx.doi.org/10.1155/2020/4945608.

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High risk human Papillomavirus (HPV) infections ultimately cause cervical cancer. Human Immunodeficiency Virus (HIV) infected women often present with multiple high-risk HPV infections and are thus at a higher risk of developing cervical cancer. However, information on the circulating high-risk HPV genotypes in Kenya in both HIV-infected and HIV-uninfected women is still scanty. This study is aimed at determining the phylogeny and the HPV genotypes in women with respect to their HIV status and at correlating this with cytology results. This study was carried out among women attending the Repro
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Guthrie, Brandon L., Anne F. Rositch, Joy Alison Cooper, et al. "Human papillomavirus and abnormal cervical lesions among HIV-infected women in HIV-discordant couples from Kenya." Sexually Transmitted Infections 96, no. 6 (2020): 457–63. http://dx.doi.org/10.1136/sextrans-2019-054052.

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ObjectiveHIV infection increases the risk of high-grade cervical neoplasia and invasive cervical carcinoma. The study addresses the limited data describing human papillomavirus (HPV) infection and cervical neoplasia among HIV-infected women in HIV-discordant relationships in sub-Saharan Africa, which is needed to inform screening strategies.MethodsA cross-sectional study of HIV-infected women with HIV-uninfected partners was conducted to determine the distribution of type-specific HPV infection and cervical cytology. This study was nested in a prospective cohort recruited between September 200
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Giffin, Leahanne, Yuwei Zhu, Manideepthi Pemmaraju, et al. "826. HIV Infection and HPV Genotype Patterns among Young Women with Advanced Cervical Neoplasia in Davidson County, Tennessee." Open Forum Infectious Diseases 8, Supplement_1 (2021): S505—S506. http://dx.doi.org/10.1093/ofid/ofab466.1022.

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Abstract Background Women living with HIV (WLWH) experience high rates of human papillomavirus (HPV) infection and increased risk of cervical cancer. High-risk HPV (HR-HPV) types 16/18 cause most cervical precancers and cancers in women with and without HIV. However, contributions of other HR-HPV types to cervical disease among WLWH are not fully understood. We compared CIN2+ cases (cervical intraepithelial neoplasia grade 2 or higher or adenocarcinoma in situ) and the association between non-16/18 HPV types among women with and without HIV. Methods Davidson County, Tennessee, women aged 18-39
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Ablanedo-Terrazas, Yuria, Karla Romero-Mora, María Gómez-Palacio, et al. "Prevalence and risk factors for oral human papillomavirus infection in Mexican HIV-infected men." Salud Pública de México 60, no. 6, nov-dic (2018): 653. http://dx.doi.org/10.21149/9834.

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Objective. To determine the prevalence and risk factors for oral high-risk human papillomavirus (HR-HPV) infection in human immunodeficiency virus (HIV)-infected men. Materials and methods. Consecutive male outpatients with HIV-infection were enrolled. Demographic and behavioral risk data were obtained. Anal swabs and oral rinses were tested for HR-HPV DNA. Oral, pharyngeal and video laryngoscopy examinations were performed for detection of lesions. Results. The prevalence of HR-HPV oral infection was 9.3% (subtypes other than HR HPV 16/18 predominated). The prevalence of anal HR-HPV infection
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Adebamowo, Sally N., Toyosi Olawande, Ayotunde Famooto, et al. "Risk, Persistence and Multiplicity of HPV Infections among HIV Negative and HIV Positive Nigerian Women." Journal of Global Oncology 2, no. 3_suppl (2016): 38s—39s. http://dx.doi.org/10.1200/jgo.2016.003830.

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Abstract 64 Background: The incidence, prevalence, persistence, and multiplicity of high-risk HPV infection is different between HIV positive and HIV negative women. We examined the association between HIV, prevalent HPV, and persistent HPV infections among women in a prospective cohort in Nigeria. Methods: We enrolled women presenting at cervical cancer screening programs in Abuja, Nigeria, between 2012 and 2014 and collected information on their demographic characteristics, risk factors of HPV infection, and cervical exfoliated cells samples at baseline, 6 month and 12 month follow-up visits
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Adler, David H., Melissa Wallace, Thola Bennie, et al. "Cervical Dysplasia and High-Risk Human Papillomavirus Infections among HIV-Infected and HIV-Uninfected Adolescent Females in South Africa." Infectious Diseases in Obstetrics and Gynecology 2014 (2014): 1–6. http://dx.doi.org/10.1155/2014/498048.

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Background.HIV-infected adolescents may be at higher risk for high-grade cervical lesions than HIV-uninfected adolescents. The purpose of this study was to compare the prevalence of high-risk HPV (HR-HPV) infections and Pap smear abnormalities between these two groups.Methods.In this cross-sectional study, we compared the HPV DNA and Pap smear results between 35 HIV-infected and 50 HIV-uninfected adolescents in order to determine the prevalence of HR-HPV genotypes and cervical cytological abnormalities. Comparisons were made using Pearsonχ2and independent-samplest-tests analyses, and associati
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Paraná, Victoria C., Davi Souza Santos, Dhara Isabella Barreto de Souza Silva, Gabriela C. Lima, Luana L. Gois, and Luciane Amorim Santos. "Anal and cervical human papillomavirus genotypes in women co-infected with human immunodeficiency virus: A systematic review." International Journal of STD & AIDS 33, no. 6 (2022): 530–43. http://dx.doi.org/10.1177/09564624221076293.

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Human papillomavirus (HPV) and human immunodeficiency virus (HIV) infections are sexually transmitted. There are several HPV genotypes and clinical manifestations. Determining which genotypes circulate worldwide and/or in specific geographic areas can help with prevention programs and vaccine distribution. This systematic review aimed to investigate the most frequent anal and cervical HPV genotypes in women co-infected with HPV/HIV. The PubMed, Scientific Electronic Library Online, and Latin American and Caribbean Literature in Health Sciences databases were used to search for articles publish
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van Schalkwyk, Cari, Jennifer Moodley, Alex Welte, and Leigh Francis Johnson. "Are associations between HIV and human papillomavirus transmission due to behavioural confounding or biological effects?" Sexually Transmitted Infections 95, no. 2 (2018): 122–28. http://dx.doi.org/10.1136/sextrans-2018-053558.

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ObjectivesCohort studies have shown significant increased risk of HIV acquisition following human papillomavirus (HPV) detection and increased risk of new HPV detection in individuals with HIV infection, after adjusting for behavioural risk factors. This study uses an individual-based model to assess whether confounding sexual behaviour factors and network level effects can explain these associations between HIV and HPV infection status, without biological interactions.MethodsThe model simulates infection with 13 oncogenic HPV types and HIV. It allows for different relationship types, with het
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Wang, Qian, Xiaomeng Ma, Xiaosong Zhang, et al. "Human papillomavirus infection and associated factors for cervical intraepithelial neoplasia in women living with HIV in China: a cross-sectional study." Sexually Transmitted Infections 95, no. 2 (2018): 140–44. http://dx.doi.org/10.1136/sextrans-2018-053636.

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ObjectiveWomen living with HIV (WLHIV) face disproportionately higher risks of acquiring human papillomavirus (HPV) compared with HIV negative counterparts. We aimed to investigate the prevalence of HPV in WLHIV in Chinese hospital setting and identify associated factors to the progression of late-stage cervical intraepithelial neoplasia (CIN2+) in this population.MethodThis retrospective study collected data from 183 WLHIV on antiretroviral treatment (ART), based on reproductive health questionnaires. Gynaecological examination results including serum (for HIV viral load, CD4 T-cell count, he
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Syrjänen, S. "Human Papillomavirus Infection and Its Association with HIV." Advances in Dental Research 23, no. 1 (2011): 84–89. http://dx.doi.org/10.1177/0022034511399914.

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Human papillomavirus (HPV) can infect oral mucosa, causing asymptomatic infection or warty lesions. Several case-control studies have confirmed HPV as an independent risk factor for squamous cell carcinoma. HPV-related cancers seem to have better prognoses and different risk factors than do HPV-negative ones. HIV-infected patients are known to be at increased risk for persistent genital and anal high-risk HPV infections and intraepithelial neoplasm. Since the era of highly active antiretroviral therapy, the prevalence and persistence of warty lesions in oral mucosa have increased. Oral squamou
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Rodrigues, Luana Lorena Silva, José Henrique Pilotto, Katrini Guidolini Martinelli, et al. "Diversity of Anal HPV and Non-HPV Sexually Transmitted Infections and Concordance with Genital Infections in HIV-Infected and HIV-Uninfected Women in the Tapajós Region, Amazon, Brazil." Viruses 15, no. 6 (2023): 1328. http://dx.doi.org/10.3390/v15061328.

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The aim of this study was to classify the diversity of anal HPV and non-HPV sexually transmitted infections (STIs) and compare the concordance between anal and genital infections in HIV-infected and uninfected women living in the Tapajós region, Amazon, Brazil. A cross-sectional study was performed with 112 HIV-uninfected and 41 HIV-infected nonindigenous women. Anal and cervical scrapings were collected and analyzed for HPV, Chlamydia trachomatis (CT), Neisseria gonorrheae (NG), Trichomonas vaginalis (TV), Mycoplasma genitalium (MG), and Human alphaherpesvirus 2 (HSV-2). The Kappa test evalua
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Ouladlahsen, Ahd, Naouar Fayssel, Rajaa Bensghir, et al. "The Human papillomavirus among women living with Human Immunodeficiency Virus in Morocco A prospective cross-sectional study." Journal of Infection in Developing Countries 12, no. 06 (2018): 477–84. http://dx.doi.org/10.3855/jidc.9711.

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Introduction: Women infected with human immunodeficiency virus (HIV) have a higher risk of contracting human papillomavirus (HPV) infections and are more prone to develop cervical cancer. The objective of this study was to determine the prevalence of HPV and its association with risk factors among Moroccan women living with HIV/AIDS.
 Methodology: We enrolled 251 HIV-infected non-pregnant women in Morocco from February 2013 to September 2016. Sociodemographic, lifestyles, behavioral and clinical data were collected. Polymerase chain reaction followed by sequencing were performed for molec
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Silverberg, Michael J., Michael F. Schneider, Barbara Silver, et al. "Serological Detection of Human Papillomavirus Type 16 Infection in Human Immunodeficiency Virus (HIV)-Positive and High-Risk HIV-Negative Women." Clinical and Vaccine Immunology 13, no. 4 (2006): 511–19. http://dx.doi.org/10.1128/cvi.13.4.511-519.2006.

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ABSTRACT Serial measurement of antibodies has not been used to provide evidence of active viral replication of human papillomavirus (HPV). Serum specimens from sequential study visits contributed by 642 human immunodeficiency virus (HIV)-positive and 116 HIV-negative participants enrolled in the Women's Interagency HIV Study were used to detect significant rises in HPV type 16 (HPV-16) antibody levels. Factors associated with a significant rise were identified using multivariable logistic regression models with generalized estimating equations. Among HIV-positive women, 8.3% of 1,997 pairs sho
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Malik, Sunita, Supriti Kumari, Harsha S. Gaikwad, Archana Mishra, and Mausumi Bharadwaj. "Prevalence of abnormal cervical cytology and HPV DNA positivity among HIV positive women." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 8, no. 9 (2019): 3649. http://dx.doi.org/10.18203/2320-1770.ijrcog20193791.

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Background: The relationship among HIV, HPV, and development of CIN is complex and incompletely understood. Present study is undertaken to find out the prevalence and relationship of abnormal cervical cytology and HPV infection in HIV positive women.Methods: This was a cross-sectional, case control study conducted on 95 HIV seropositive and 95 seronegative women. Specimen was collected from the cervix for HPV DNA testing, subtyping and cytology.Results: HPV DNA positivity was higher in seropositive group (18.6% vs. 7.4%). Premalignant conditions were found only in seropositive group. At CD4 co
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Muwonga Tukisadila, Jonathan, Ralph-Sydney Mboumba Bouassa, Serge Tonen-Wolyec, Hugues Loemba, Jeremie Muwonga, and Laurent Belec. "Syndemic Synergy of HPV, HIV, and HSV-2 for Oncogenic HPV Replication in Female Sex Workers." Tropical Medicine and Infectious Disease 10, no. 6 (2025): 157. https://doi.org/10.3390/tropicalmed10060157.

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Background: Female sex workers (FSWs) in sub-Saharan Africa bear a disproportionate burden of sexually transmitted infections, including HIV, high-risk HPV (HR-HPV), and herpes simplex virus type 2 (HSV-2). This study evaluated possible association between HR-HPV, HIV, and HSV-2 among FSWs in the Democratic Republic of the Congo. Methods: A cross-sectional study was conducted among 432 FSWs (mean age, 28.1 years) recruited via respondent-driven sampling. Genital self-sampling using the V-Veil UP2™ device was performed, followed by HPV genotyping and quantification by multiplex PCR, and HSV-2 D
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Visalli, Giuseppa, Angela Di Pietro, Monica Currò, et al. "How Much Does HIV Positivity Affect the Presence of Oral HPV? A Molecular Epidemiology Survey." International Journal of Environmental Research and Public Health 18, no. 17 (2021): 8999. http://dx.doi.org/10.3390/ijerph18178999.

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HIV-positive people showed a high oral prevalence of HPV-DNA and have a greater incidence of head and neck carcinomas compared to general population. We performed a molecular survey evaluating the presence of HPV-DNA in saliva of HIV-positive and HIV-negative subjects in order to quantify the risk represented by HIV-positivity. The sample was made up by 102 subjects: 40 HIV-positive, 32 HIV-negative with sexual risk behaviors (SRB) and 30 HIV-negative without risk factors. DNA was extracted from cellular pellets and HPV detection and genotyping were performed by PCR assays. In the HIV-positive
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Ren, Xuqi, Wujian Ke, Heping Zheng, et al. "Human Papillomavirus Positivity in the Anal Canal in HIV-Infected and HIV-Uninfected Men Who Have Anal Sex with Men in Guangzhou, China: Implication for Anal Exams and Early Vaccination." BioMed Research International 2017 (2017): 1–9. http://dx.doi.org/10.1155/2017/2641259.

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Background. The epidemiology of HPV in men who have sex with men (MSM) in Guangzhou, China, had not been reported previously. Methods. HIV-infected and HIV-uninfected MSM were recruited from a Guangzhou-based MSM clinic in 2013. Sociodemographic characteristics and sexual behaviors were collected. An anal cytological sample was taken for HPV testing. Results. We recruited 79 HIV-infected and 85 HIV-uninfected MSM. The median age was 26 years in both groups. The positivities of anal HPV of any type (81.0% versus 48.2%), any high risk type (50.6% versus 27.1%), any low risk type (55.7% versus 31
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Wittawatmongkol, Orasri, Sivaporn Gatechompol, Stephen J. Kerr, et al. "Human papillomavirus infection among male adolescents and young adults with perinatally-acquired HIV and without HIV in Thailand." International Journal of STD & AIDS 30, no. 10 (2019): 960–68. http://dx.doi.org/10.1177/0956462419853384.

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HIV infection may increase the risk of persistent human papillomavirus (HPV) infection and complications. Male adolescents and young adults (AYAs) with perinatally-acquired HIV (PHIV) and without HIV in Thailand were matched by age and lifetime number of sexual partners. HPV infection at oral, anal, penile, and scrotal sites was detected by polymerase chain reaction. A total of 49 PHIV and 47 HIV-uninfected male AYAs (median age 18 [17–20] years) were enrolled (June 2013–September 2014). Overall, 18 were men who have sex with men (MSM) (12% of PHIV, 26% of HIV-uninfected AYAs; P = 0.12). Among
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Kusuma, Fitriyadi, Kemal Akbar Suryoadji, Muhammad Raoul Taufiq Abdullah, et al. "Prevalensi Infeksi Human Papilloma Virus Risiko Tinggi Pada Wanita dengan Positif Human Immunodeficiency Virus di Dunia: Tinjauan Sistematis Berdasarkan Studi Terkini." Jurnal Ilmiah Kesehatan 22, no. 02 (2023): 96–101. http://dx.doi.org/10.33221/jikes.v22i02.2652.

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Tipe Human Papilloma Virus (HPV) risiko tinggi merupakan etiologi dari kanker serviks yang menjadi kanker kedua terbesar pada wanita. Infeksi Human Immunodeficiency Virus (HIV) menjadi salah satu faktor risiko infeksi HPV. Pada pasien dengan HIV terjadi penurunan sistem imun yang dapat menyebabkan peningkatan risiko infeksi terlebih jika kadar CD4+ rendah. Untuk menelusuri seberapa banyak wanita dengan HIV yang terinfeksi virus HPV risiko tinggi pada berbagai penelitian terkini. Penelusuran dilakukan dengan metode systematic review menggunakan database Pubmed, Cochrane, dan ScienceDirect. Digu
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Fang, Qimin. "HPV co-infection in HIV-positive individuals: Epidemiological trends and public health implications." Theoretical and Natural Science 35, no. 1 (2024): 237–40. http://dx.doi.org/10.54254/2753-8818/35/20240807.

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This paper examines the epidemiological trends, influencing factors and potential public health implications of HPV co-infection in HIV-infected people. The incidence of HPV co-infection in HIV-infected people is relatively high, which is influenced by multiple factors such as immunosuppression, sexual risk and treatment history. HPV co-infection clearly increases the risk of related cancers such as cervical cancer, highlighting the importance of timely HPV screening and cervical cancer prevention. The use of HPV vaccines in people with HIV has potential value, but more research is needed to s
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Cardoso Marques, Marcos Paulo, Amanda Chaves Pinto, Leila Cristina Soares, Jacyara Maria Brito Macedo, Debora Fontenelle dos Santos, and Marco Aurelio Pinho Oliveira. "Differences in HPV infection and HPV-related lesions between the cervix and anus in hiv-positive women." Revista de Ciências Médicas e Biológicas 20, no. 2 (2021): 229–34. http://dx.doi.org/10.9771/cmbio.v20i2.43354.

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Introduction: the prevalence of cervical and anal human papillomavirus (HPV) infection in women infected with human immunodeficiency virus (HIV) is high. However, little is known about the differences in the susceptibility of these infections and related lesions. The aim of this study was to describe the association between the prevalence of cervical and anal HPV infection and HPV-related lesions in HIV-positive women. Methods: this study included 88 HIV-positive women attending an outpatient clinic in a university hospital. Ectocervical, endocervical, and anal samples were collected for colpo
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Taku, Ongeziwe, Zizipho Z. A. Mbulawa, Keletso Phohlo, Mirta Garcia-Jardon, Charles B. Businge, and Anna-Lise Williamson. "Distribution of Human Papillomavirus (HPV) Genotypes in HIV-Negative and HIV-Positive Women with Cervical Intraepithelial Lesions in the Eastern Cape Province, South Africa." Viruses 13, no. 2 (2021): 280. http://dx.doi.org/10.3390/v13020280.

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South African women have a high rate of cervical cancer cases, but there are limited data on human papillomavirus (HPV) genotypes in cervical intraepithelial neoplasia (CIN) in the Eastern Cape province, South Africa. A total of 193 cervical specimens with confirmed CIN from women aged 18 years or older, recruited from a referral hospital, were tested for HPV infection. The cervical specimens, smeared onto FTA cards, were screened for 36 HPV types using an HPV direct flow kit. HPV prevalence was 93.5% (43/46) in CIN2 and 96.6% (142/147) in CIN3. HIV-positive women had a significantly higher HP
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