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1

Sestak, Ivana, Roseann Kealy, Robert Edwards, John Forbes, and Jack Cuzick. "Influence of Hormone Replacement Therapy on Tamoxifen-Induced Vasomotor Symptoms." Journal of Clinical Oncology 24, no. 24 (2006): 3991–96. http://dx.doi.org/10.1200/jco.2005.04.3745.

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Purpose Tamoxifen is an effective drug, but its role in prevention is limited by its adverse effect profile. Non–life-threatening adverse effects, such as vasomotor symptoms, have an important influence in its use for prevention. Vasomotor symptoms were evaluated according to follow-up time, severity, and use of hormone replacement therapy (HRT) in a retrospective analysis. Patients and Methods In the International Breast Cancer Intervention Study-I study, 7,154 women at increased risk of breast cancer were randomly assigned to either tamoxifen 20 mg/d or placebo for 5 years. Women gave detail
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2

Zhou, Jue, Fan Qu, Xisheng Sang, Xiaotong Wang, and Rui Nan. "Acupuncture and Auricular Acupressure in Relieving Menopausal Hot Flashes of Bilaterally Ovariectomized Chinese Women: A Randomized Controlled Trial." Evidence-Based Complementary and Alternative Medicine 2011 (2011): 1–8. http://dx.doi.org/10.1093/ecam/nep001.

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The objective of this study is to explore the effects of acupuncture and auricular acupressure in relieving menopausal hot flashes of bilaterally ovariectomized Chinese women. Between May 2006 and March 2008, 46 bilaterally ovariectomized Chinese women were randomized into an acupuncture and auricular acupressure group (n= 21) and a hormone replacement therapy (HRT) group (Tibolone,n= 25). Each patient was given a standard daily log and was required to record the frequency and severity of hot flashes and side effects of the treatment felt daily, from 1 week before the treatment started to the
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3

Taylor, Abi. "Non-hormonal treatments of menopausal symptoms." InnovAiT: Education and inspiration for general practice 12, no. 12 (2019): 703–5. http://dx.doi.org/10.1177/1755738019874829.

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Many women with menopausal symptoms will consult their GP for help and advice. These symptoms can be varied and include vasomotor symptoms (hot flushes and night sweats), urogenital dryness or irritation, muscle aches, poor sleep and low mood. For some women, explanation and reassurance may be all that is required; others may request treatment with hormone-replacement therapy (HRT). However, some women requesting treatment will not be able to take HRT, due to co-existing medical problems such as breast cancer or may wish to avoid hormones for other reasons. This article will describe some of t
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4

Huang, Marilyn, Charlotte C. Sun, Shannon Neville Westin, and Diane C. Bodurka. "Hormone replacement therapy (HRT) prescribing patterns among gynecologic oncologists." Journal of Clinical Oncology 31, no. 15_suppl (2013): e20637-e20637. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e20637.

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e20637 Background: Gynecologic cancer survivors have indicated inadequate treatment of their menopausal symptoms; and while HRT can significantly improve quality of life (QOL) its safety is still debated. Our objective was to evaluate HRT practice patterns and identify potential barriers to prescribing HRT among gynecologic oncologists (GO). Methods: SGO members with active electronic mail (n=823) were queried with single answer and Likert-style questions using an internet-based program. Email reminders were sent at 3, 6, and 9 weeks. Results: Of 207 respondents (25%), 123 (59%) were male and
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Sravanthi, Desaboina, E. Kayalvizhi, Savitha Niren, M. Arun Kumar, and Nasser Habibur Rahman. "Hormonal changes and cancer risk in post-menopausal women: HRT vs. seed supplementation." Romanian Medical Journal 72, no. 2 (2025): 170–76. https://doi.org/10.37897/rmj.2025.2.2.

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Introduction. Menopausal symptoms such as hot flashes, night sweats, and hormonal imbalances are common in postmenopausal women. This study compares the effects of hormone replacement therapy (HRT) and seed supplementation on hormonal levels, cancer risk markers, and menopausal symptoms. Material and methods. A randomized controlled trial was conducted from November 2021 to October 2022 at Mamata Academy of Medical Sciences, Hyderabad. A total of 150 postmenopausal women (aged 40–55 years) were randomized into three groups: Group I (control, n=50), Group II (seed supplementation, 20 g/day for
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Ushiroyama, Takahisa, Atsushi Ikeda, Kou Sakuma, and Minoru Ueki. "Comparing the Effects of Estrogen and an Herbal Medicine on Peripheral Blood Flow in Post-menopausal Women with Hot Flashes: Hormone Replacement Therapy and Gui-Zhi-Fu-Ling-Wan, a Kampo Medicine." American Journal of Chinese Medicine 33, no. 02 (2005): 259–67. http://dx.doi.org/10.1142/s0192415x05002813.

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We investigated the association between blood flow in the extremities and hot flashes, and compared change in blood flow following hormone replacement therapy (HRT) and Gui-zhi-fu-ling-wan (Keishi-bukuryo-gan), a herbal therapy in post-menopausal women with hot flashes. Three hundred and fifty-two post-menopausal women aged 46–58 years (mean: 53.4±3.6 years) with climacteric complaints participated in the study. One hundred and thirty-one patients with hot flashes were treated with HRT (64 cases) or herbal therapy (67 cases). Blood flow was measured with laser doppler fluxmetry under the jaw,
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Nido, Miriam, Lena Schneider, and Benedikt Hell. "Studie «Personalentwicklung im Wandel»: Digitalisierungsschub dank Covid." personalSCHWEIZ, no. 1 (January 1, 2022): 32–34. https://doi.org/10.5281/zenodo.5832984.

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Studie «Personalentwicklung im Wandel» Digitalisierungsschub dank Covid Die Covid-Pandemie stellt die Personalentwicklung von Schweizer Unternehmen vor neue Herausforderungen. Viele traditionelle Formate konnten im vergangenen Jahr nicht fortgeführt werden. Ob die Pandemie zu einem Digitalisierungsschub geführt hat und wie die Unternehmen auf die neuen Herausforderungen reagieren, klärt die vorliegende Studie.
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8

Moore, Anne. "After HRT." Nursing 33 (June 2003): 13–15. http://dx.doi.org/10.1097/00152193-200306001-00006.

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Cotard, Sylvain, Audrey Queudet, Jean-Luc Béchennec, Sébastien Faucou, and Yvon Trinquet. "STM-HRT." ACM Transactions on Embedded Computing Systems 14, no. 4 (2015): 1–25. http://dx.doi.org/10.1145/2786979.

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10

Aschenbrenner, Diane S. "HRT Reconsidered." AJN, American Journal of Nursing 104, no. 6 (2004): 51–53. http://dx.doi.org/10.1097/00000446-200406000-00031.

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11

Mugada, Vinodkumar, Raj Kiran Kolakota, Sujana Bhargavi Jadda, Urmila Kotapadu, and Mounika Veesam. "Does hormone replacement therapy benefit post-menopausal women? – a scoping review." Medical Science Pulse 13, no. 2 (2019): 52–57. http://dx.doi.org/10.5604/01.3001.0013.1367.

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Post-menopausal women experience symptoms such as irregular periods, lower fertility, vaginal dryness, hot flashes and night sweats. Hormone replacement therapy (HRT) relieves menopausal symptoms. The aim of this review was to assess the benefits and risks of HRT in post-menopausal women. A scoping review was conducted for original peer-reviewed English language papers using the electronic databases of PUBMED, JAMA, BMC and TRIP. The papers were subjected to a three-stage screening process. The type of study, year of study, age, participants, type of therapy and the aim of the study defined th
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12

Eman, Elmahjoubi, Rghebi Nabila, Benamer Wadiaa, and Yamane Mufida. "Are there Opportunities for a Specialist Menopause Pharmacist in Libya?" AlQalam Journal of Medical and Applied Sciences 4, no. 1 (2021): 107–15. https://doi.org/10.5281/zenodo.4514686.

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Background and objectives: Menopause is the permanent cessation of menses following the loss of ovarian follicular activity. It occurs usually in women in the age range of 45-58 years. The focus of this study was to evaluate the knowledge of Libyan pharmacists about menopause, and its management. The other aim is to determine the attitude towards menopause and Hormone Replacement Therapy (HRT) among Libyan women. Materials and Methods: A prospective, structured face-to-face interview was conducted between November 2017 and February 2018. Two different questionnaires were designed; the first on
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13

Hamzik, Mary P., Andrea L. Gropman, Michaela R. Brooks, Sherida Powell, Teresa Sadeghin, and Carole A. Samango-Sprouse. "The Effect of Hormonal Therapy on the Behavioral Outcomes in 47,XXY (Klinefelter Syndrome) between 7 and 12 Years of Age." Genes 14, no. 7 (2023): 1402. http://dx.doi.org/10.3390/genes14071402.

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47,XXY, also known as Klinefelter syndrome, is the most commonly occurring sex chromosomal aneuploidy (SCA). Hormonal replacement therapy (HRT) has been associated with improved neurodevelopmental capabilities in boys with 47,XXY, although studies investigating HRT’s possible positive effect on behavioral outcomes are scarce. This study explores the association between behavioral outcomes and HRT in boys ages 7–12. Patients were divided into 4 groups based on HRT status: untreated, early hormonal treatment (EHT), hormonal booster therapy (HBT), and both EHT and HBT. Analysis of Variance (ANOVA
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Comparetto, Ciro, and Franco Borruto. "Treatments and Management of Menopausal Symptoms: Current Status and Future Challenges." OBM Geriatrics 07, no. 03 (2023): 1–47. http://dx.doi.org/10.21926/obm.geriatr.2303248.

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In the United States (US), menopause occurs at an average age of 52. Menopausal symptoms tend to be maximal during the few years before and the year after menopause (during perimenopause), except for symptomatic vulvovaginal atrophy, which may worsen over time. Up to 20% of bone density loss occurs during the first 5 years after menopause, followed by an age-related bone loss rate similar to that in men. Menopause should be considered confirmed if an age-appropriate woman who is not pregnant has not had a menstrual period for 12 months. Regarding treatment, for vaginal dryness or dyspareunia d
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15

H�ring, R., H. Hamelmann, C. M�ller, F. Harder, R. Pichlmayr, and J. R. Siewert. "Der problematische Bauchdeckenverschlu� ?? was hat sich bew�hrt?" Langenbecks Archiv f�r Chirurgie 365, no. 1 (1985): 69–74. http://dx.doi.org/10.1007/bf01261214.

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16

Fowble, Barbara, Alexandra Hanlon, Gary Freedman, et al. "Postmenopausal Hormone Replacement Therapy: Effect on Diagnosis and Outcome in Early-Stage Invasive Breast Cancer Treated With Conservative Surgery and Radiation." Journal of Clinical Oncology 17, no. 6 (1999): 1680. http://dx.doi.org/10.1200/jco.1999.17.6.1680.

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PURPOSE: To compare the pretreatment characteristics and outcome of postmenopausal women with stage I-II breast cancer treated with conservative surgery and radiation who had a history of hormone replacement therapy (HRT) with those who had never received HRT. MATERIALS AND METHODS: From 1979 to 1993, 485 postmenopausal women underwent excisional biopsy, axillary dissection, and radiation for stage I-II breast cancer. The median follow-up was 5.9 years. One hundred forty-one patients reported a history of HRT. The median length of use was 5 years. Three hundred forty-four patients reported no
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17

Balasubramanian, Madhusudhanan, Christopher Bowd, Robert N. Weinreb, and Linda M. Zangwill. "Agreement between the Heidelberg Retina Tomograph (HRT) Stereometric Parameters Estimated Using HRT-I and HRT-II." Optometry and Vision Science 88, no. 1 (2011): 140–49. http://dx.doi.org/10.1097/opx.0b013e3181fc3467.

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18

Putri, Biomechy Oktomalio, and Noverial Noverial. "Efek Pemakaian Hormone Replacement Therapy (HRT): Systematic Review." Jurnal Kesehatan Andalas 12, no. 1 (2023): 39. http://dx.doi.org/10.25077/jka.v12i1.2131.

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Menopausal women have a risk of suffering from several diseases due to decreased levels of the hormone estrogen in the body. One effort to reduce this risk is to use Hormone Replacement Therapy (HRT). Objective: To analyzed the effect of HRT use on postmenopausal women.Methods: This research was a systematic review by searching articles in the PubMed electronic journal with keywords used [“Premenopausal women” OR “Postmenopausal women”, OR “Menopause”] AND [“Hormone Replacement Therapy” OR “Menopausal Hormone Therapy”] AND [“Increased risk disease” OR “Decreased risk disease”]. Results: There
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19

Ji, Eunjeong, Kidong Kim, Banghyun Lee, et al. "Postoperative Hormone Replacement Therapy and Survival in Women with Ovarian Cancer." Cancers 14, no. 13 (2022): 3090. http://dx.doi.org/10.3390/cancers14133090.

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The effect of postoperative hormone replacement therapy (HRT) on survival in women with ovarian cancer remains unclear. This study aimed to investigate the impact of postoperative HRT on survival in women with ovarian cancer using the nationwide cohort study. Women aged ≤60 and diagnosed with ovarian cancer that received primary surgery were followed-up for 5.6 ± 2.9 years. Mean ages of women administered HRT (the HRT group; n = 263) or not administered HRT (the control group; n = 1521) were 41.5 ± 8.5 and 41.0 ± 11.4 years, respectively. After adjustment for covariables, OS was significantly
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20

Moreau, Kerrie L., Anthony J. Donato, Douglas R. Seals, et al. "Arterial intima-media thickness: site-specific associations with HRT and habitual exercise." American Journal of Physiology-Heart and Circulatory Physiology 283, no. 4 (2002): H1409—H1417. http://dx.doi.org/10.1152/ajpheart.00035.2002.

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We determined the site-specific relations of hormone replacement therapy (HRT) and habitual exercise status with intima-media thickness (IMT) in both elastic (carotid) and muscular (femoral) arteries in 77 healthy postmenopausal women: 43 women were sedentary (20 no-HRT and 23 HRT users) and 34 women were endurance trained (14 no-HRT and 20 HRT users). Femoral IMT was not different among the sedentary HRT and endurance-trained no-HRT and HRT groups, but was lower ( P < 0.005) in these three groups than in the sedentary no-HRT women. There were no significant group differences in carotid IMT
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21

Meyer, Casey J., J. Craig Garrison, and John E. Conway. "Baseball Players With an Ulnar Collateral Ligament Tear Display Increased Nondominant Arm Humeral Torsion Compared With Healthy Baseball Players." American Journal of Sports Medicine 45, no. 1 (2016): 144–49. http://dx.doi.org/10.1177/0363546516664718.

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Background: Previous work has suggested that an increase in the amount of developmentally acquired, dominant arm humeral retrotorsion (D HRT) in the thrower’s shoulder may be a potentially protective mechanism. Although the relationship between HRT and shoulder injuries has been reported, the relationship between HRT and ulnar collateral ligament (UCL) tears in baseball players is not known. Purpose: To determine whether D HRT and nondominant arm HRT (ND HRT) measurements in baseball players with a UCL tear differ statistically from a matched healthy cohort. Study Design: Case-control study; L
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22

Kohrt, Wendy M., Ali A. Ehsani, and Stanley J. Birge. "HRT preserves increases in bone mineral density and reductions in body fat after a supervised exercise program." Journal of Applied Physiology 84, no. 5 (1998): 1506–12. http://dx.doi.org/10.1152/jappl.1998.84.5.1506.

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The aims of this study were to confirm our previous finding that hormone-replacement therapy (HRT) augments exercise-induced increases in bone mineral density (BMD) in older women and to determine whether HRT preserves the adaptations when exercise is reduced or discontinued. The study included an 11-mo treatment phase and a 6-mo follow-up phase. Participants, aged 66 ± 3 yr, were assigned to control (Con; n = 10), exercise (Ex; n = 18), HRT ( n = 10), and Ex+HRT ( n = 16) groups. HRT was continued during the follow-up. After the treatment phase, changes in total body BMD were −0.5 ± 1.7, 1.5
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Anderson, Pippa, Caroline O’Leary, Margaret Moffat, and Xuemei Luo. "Hormone replacement therapy use in UK general practice: Duration, discontinuation and women’s experience." Post Reproductive Health 22, no. 4 (2016): 155–64. http://dx.doi.org/10.1177/2053369116675712.

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Objective Investigate characteristics of women treated with combined estrogen and progestogen hormone replacement therapy (study-HRT); HRT patterns; reasons and outcomes associated with HRT discontinuation. Study design Retrospective observational study using The Health Improvement Network database examining women’s characteristics and treatment patterns (Database). Postal questionnaire exploring reasons and outcomes associated with HRT discontinuation (Survey). Main outcome measures Database: Demographic and clinical characteristics. HRT patterns, time from diagnosis to treatment, duration of
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Abdullahi Idle, Salwa, and Haitham Hamoda. "Outcomes of endometrial assessment in women with unscheduled bleeding on hormone replacement therapy." Post Reproductive Health 25, no. 2 (2019): 95–99. http://dx.doi.org/10.1177/2053369119830822.

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Objective This study correlates the transvaginal ultrasound findings with histopathology results in women who present with unscheduled bleeding on hormone replacement therapy. Study design Retrospective analysis of 469 consecutive cases with unscheduled bleeding on hormone replacement therapy (203 patients on sequential hormone replacement therapy (seq-HRT) and 266 patients on continuous combined hormone replacement therapy (con-HRT)). Main outcome measures Outcomes of endometrial assessment in women with unscheduled bleeding on hormone replacement therapy. Results Normal appearance of the end
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Punay, N., and J. W. W. Studd. "HRT and depression." Gynecological Endocrinology 10, sup4 (1996): 24–26. http://dx.doi.org/10.3109/09513599609116169.

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&NA;. "Long-term HRT." Inpharma Weekly &NA;, no. 1129 (1998): 12. http://dx.doi.org/10.2165/00128413-199811290-00026.

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&NA;. "HRT + etidronic acid." Inpharma Weekly &NA;, no. 1137 (1998): 19. http://dx.doi.org/10.2165/00128413-199811370-00034.

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Lynch, Elizabeth. "HRT: the risks." Nursing Standard 17, no. 50 (2003): 12–13. http://dx.doi.org/10.7748/ns.17.50.12.s23.

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&NA;. "Risks of HRT." Inpharma Weekly &NA;, no. 1636 (2008): 19. http://dx.doi.org/10.2165/00128413-200816360-00057.

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&NA;. "Risks of HRT." Reactions Weekly &NA;, no. 1200 (2008): 6. http://dx.doi.org/10.2165/00128415-200812000-00012.

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Shaheen, Shugufta, Anila Mahmood, Farzana Kadri, and Ana Mehreen Rajput. "MENOPAUSE AND HRT." Professional Medical Journal 22, no. 07 (2015): 904–9. http://dx.doi.org/10.29309/tpmj/2015.22.07.1180.

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Objective: To find out awareness about menopause and HRT in thepostmenopausal women. Study Design: Cross sectional and observational study. Setting:Gynaecological Department of Al Tibiri Medical College Isra University, Karachi Campus andLady Dufferin Hospital Karachi. Period: May 2013 to December 2013. Method: Total 150women were selected in the study. All the cases were undergone interviewed after takingconsent form. All the data regarding residential status and awareness about menopause andHRT, along socioeconomic characteristics were entered on Performa. Results: The meanage of respondents
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&NA;. "New HRT formulation." Inpharma Weekly &NA;, no. 889 (1993): 20. http://dx.doi.org/10.2165/00128413-199308890-00049.

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Sturdee, David W. "Newer HRT regimens." BJOG: An International Journal of Obstetrics and Gynaecology 104, no. 10 (1997): 1109–15. http://dx.doi.org/10.1111/j.1471-0528.1997.tb10932.x.

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Peet, Danielle. "Menopause and HRT." InnovAiT: Education and inspiration for general practice 2, no. 1 (2009): 10–16. http://dx.doi.org/10.1093/innovait/inn168.

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Glenville, M. "Alternatives to HRT." Focus on Alternative and Complementary Therapies 3, no. 4 (2010): 185. http://dx.doi.org/10.1111/j.2042-7166.1998.tb00924.x.

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Caswell, Amanda. "Hooked on HRT." Medical Journal of Australia 157, no. 5 (1992): 334. http://dx.doi.org/10.5694/j.1326-5377.1992.tb137193.x.

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Rees, Margaret. "Alternatives to HRT." Medicine 34, no. 1 (2006): 43–44. http://dx.doi.org/10.1383/medc.2006.34.1.43.

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Compston, J. E. "HRT and osteoporosis." British Medical Bulletin 48, no. 2 (1992): 309–44. http://dx.doi.org/10.1093/oxfordjournals.bmb.a072549.

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Leyland, Sarah. "Osteoporosis and HRT." Practice Nursing 11, no. 15 (2000): 19–22. http://dx.doi.org/10.12968/pnur.2000.11.15.4482.

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Cust, M. P. "Menopause and HRT." Current Obstetrics & Gynaecology 7, no. 4 (1997): 246–48. http://dx.doi.org/10.1016/s0957-5847(97)80042-x.

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Simkin, Sandra. "HRT results questioned." Lancet 356, no. 9242 (2000): 1690. http://dx.doi.org/10.1016/s0140-6736(05)70402-5.

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Barlow, David H. "HRT and osteoporosis." Baillière's Clinical Rheumatology 7, no. 3 (1993): 535–48. http://dx.doi.org/10.1016/s0950-3579(05)80077-9.

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Römer, Thomas. "Blutungsstörungen unter HRT." Journal für Gynäkologische Endokrinologie/Schweiz 23, no. 2 (2020): 44–50. http://dx.doi.org/10.1007/s41975-020-00140-5.

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Mueck, Alfred O. "Hypertension and HRT." International Congress Series 1229 (February 2002): 115–22. http://dx.doi.org/10.1016/s0531-5131(01)00460-5.

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Chakrabortti, D. K. "HRT following hysterectomy." International Journal of Gynecology & Obstetrics 70 (2000): C31. http://dx.doi.org/10.1016/s0020-7292(00)81510-6.

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Wolfman, W. L. "HRT and antidepressants." Canadian Medical Association Journal 173, no. 3 (2005): 237. http://dx.doi.org/10.1503/cmaj.1050022.

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Symon, K. "HRT and antidepressants." Canadian Medical Association Journal 173, no. 3 (2005): 237–38. http://dx.doi.org/10.1503/cmaj.1050024.

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Lee, Deborah J. "Cerazette and HRT." Journal of Family Planning and Reproductive Health Care 33, no. 3 (2007): 222. http://dx.doi.org/10.1783/147118907781004967.

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Mellor, S., A. Stirling, V. Ramsden, G. Thomas, and E. Bennett. "Guidelines for HRT." British Menopause Society Journal 1, no. 1 (1995): 21. http://dx.doi.org/10.1177/136218079500100114.

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Kanis, John. "Bones and HRT." British Menopause Society Journal 1, no. 2 (1995): 28–29. http://dx.doi.org/10.1177/136218079500100213.

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