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Relevant bibliographies by topics / HSP-90 alpha

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Journal articles

Academic literature on the topic 'HSP-90 alpha'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "HSP-90 alpha"

1

Anand, Athira Vimala, and Sukumaran. "ANTINEOPLASTIC EFFICACY OF SMILAX WIGHTII A.DC. (SMILACACEAE) AND ITS STEROIDAL SAPOGENINS: IN VITRO TO IN SILICO APPROACHES." Journal of Applied Biological Sciences 16, no. 1 (2022): 1–12. https://doi.org/10.5281/zenodo.5823038.

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Competency of plant metabolites and derivatives as antineoplastic drugs has been validated by modern medicine and the screening of flora for anticancer agents is crucial in drug discovery. <em>Smilax wightii </em>A.DC. (Smilacaceae) is an ethnomedicinal plant endemic to Western Ghats of India. The methanolic extract of various plant parts were subjected to investigation of antiproliferative potential. Dalton’s lymphoma Ascites (DLA), Ehrlich-Lettre ascites carcinoma (EAC), rat spleen, mouse fibroblast (L929) and human lung cancer (A549) cell lines were employed in the analysis. Stem extr

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2

Piura, Ettie, and Benjamin Piura. "Autoantibodies to Tumor-Associated Antigens in Breast Carcinoma." Journal of Oncology 2010 (2010): 1–14. http://dx.doi.org/10.1155/2010/264926.

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Autoantibodies (AAbs) to tumor-associated antigens (TAAs) have been identified in the circulation of patients with cancer. This paper will focus on recent knowledge related to circulating AAbs to TAAs in breast carcinoma. So far, the following TAAs have been identified to elicit circulating AAbs in breast carcinoma: p53, MUC-1, heat shock proteins (HSP-27, HSP-60, and HSP-90), HER2/neu/c-erb B2, GIPC-1, c-myc, c-myb, cancer-testis antigens (NY-ESO-1), BRCA1, BRCA2, endostatin, lipophilin B, cyclin B1, cyclin D1, fibulin, insulin-like growth factor binding protein 2 (IGFBP-2), topoisomerase II

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3

Anand, Athira Vimala, and Swapna T. Sukumaran. "ANTINEOPLASTIC EFFICACY OF SMILAX WIGHTII A.DC. (SMILACACEAE) AND ITS STEROIDAL SAPOGENINS: IN VITRO TO IN SILICO APPROACHES." Journal of Applied Biological Sciences 16, no. 1 (2022): 1–12. https://doi.org/10.71336/jabs.837.

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. Competency of plant metabolites and derivatives as antineoplastic drugs has been validated by modern medicine and the screening of flora for anticancer agents is crucial in drug discovery. Smilax wightii A.DC. (Smilacaceae) is an ethnomedicinal plant endemic to Western Ghats of India. The methanolic extract of various plant parts were subjected to investigation of antiproliferative potential. Dalton’s lymphoma Ascites (DLA), Ehrlich-Lettre ascites carcinoma (EAC), rat spleen, mouse fibroblast (L929) and human lung cancer (A549) cell lines were employed in the analysis. Stem extract exhibited

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4

Schmidt, J. A., and E. Abdulla. "Down-regulation of IL-1 beta biosynthesis by inducers of the heat-shock response." Journal of Immunology 141, no. 6 (1988): 2027–34. http://dx.doi.org/10.4049/jimmunol.141.6.2027.

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Abstract The effect of heat on IL-1 beta biosynthesis was investigated in both THP-1 cells, a myelomonocytic cell line which can be induced to make IL-1 alpha and beta, and human peripheral blood adherent monocytes (PBMC). Induction of THP-1 cells with LPS at 39 to 41 degrees C for 2 to 4 h resulted in the expected increased synthesis of the heat-shock proteins hsp 70 and hsp 90 but decreased synthesis of the IL-1 beta precursor protein, p35 (and its mRNA), compared with control cells at 37 degrees C. This appeared to be a direct effect on p35 synthesis rather than a block in LPS induction bec

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5

Eschricht, S., K. U. Jarr, C. Kuhn, H. Katus, N. Frey, and E. Chorianopoulos. "Calcineurin A stabilizes hypoxia-inducible factor-1 alpha via a heat shock protein (HSP) 90 dependent mechanism in myocardial hypertrophy." European Heart Journal 34, suppl 1 (2013): 37. http://dx.doi.org/10.1093/eurheartj/eht307.37.

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6

WU, W. "Differential effects of labor on heat shock protein (Hsp) 90 $alpha; and $beta; mRNA expression in the pregnant sheep uterus." Journal of the Society for Gynecologic Investigation 3, no. 2 (1996): 101A. http://dx.doi.org/10.1016/1071-5576(96)82532-9.

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7

Løken, S. B., I. Skrede, and T. Schumacher. "The Helvella corium species aggregate in Nordic countries – phylogeny and species delimitation." Fungal Systematics and Evolution 5, no. 1 (2020): 169–86. http://dx.doi.org/10.3114/fuse.2020.05.11.

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Mycologists have always been curious about the elaborate morphotypes and shapes of species of the genus Helvella. The small, black, cupulate Helvella specimens have mostly been assigned to Helvella corium, a broadly defined morpho-species. Recent phylogenetic analyses, however, have revealed an aggregate of species hidden under this name. We performed a multispecies coalescent analysis to re-assess species limits and evolutionary relationships of the Helvella corium species aggregate in the Nordic countries. To achieve this, we used morphology and phylogenetic evidence from five loci – heat sh

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8

Wang, Wenxiang, Ce Yang, Jing Xia, Ning Li, and Wei Xiong. "Luteolin is a potential inhibitor of COVID-19: An in silico analysis." Medicine 102, no. 38 (2023): e35029. http://dx.doi.org/10.1097/md.0000000000035029.

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The severe respiratory syndrome 2019 novel coronavirus disease (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread explosively, raising global health concerns. Luteolin shows antiviral properties, but its effect on SARS-CoV-2 and the associated mechanisms are not elucidated. We used network pharmacology, molecular docking and molecular dynamics to provide potential molecular support of luteolin (3,4,5,7-tetrahydroxyflavone) (LUT) against COVID-19. We employed network pharmacology, molecular docking, and molecular dynamics techniques to investigate h

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9

Suzuki, Mizuho, Kyosuke Takeshita, Yuki Kitamura, et al. "In Vitro Exposure to Glucose Alters the Expression of Phosphorylated Proteins in Platelets." Biomedicines 11, no. 2 (2023): 543. http://dx.doi.org/10.3390/biomedicines11020543.

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Diabetes mellitus (DM) is a pro-thrombotic state that can potentially cause serious cardiovascular complications. Platelet hyperactivation plays an important role in these pathological processes, however there is little or no information on the effect of hyperglycemia on platelet proteins. The aim of this study was to identify the molecular targets associated with platelet reactivity under hyperglycemia. Towards this goal, we examined the effects of the exposure of platelets to 1 and 2 h glucose (300 mg/dL) and control (vehicle and osmolality control using mannitol) on platelet proteins (n = 4

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10

Tissing, Wim, Jules P. P. Meijerink, Monique L. den Boer, Bas Brinkhof, and Rob Pieters. "RNA Expression Levels of (Co)Chaperone Molecules of the Glucocorticoid Receptor Are Not Related to In Vitro Prednisolone Resistance in Childhood ALL." Blood 104, no. 11 (2004): 4485. http://dx.doi.org/10.1182/blood.v104.11.4485.4485.

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Abstract In vitro resistance to Glucocorticoids (GC) is an important adverse risk factor in the treatment of ALL. To induce apoptosis in ALL cells, GC have to bind to the GC receptor (hGR), which is tightly regulated by various (co)chaperone molecules. HSP70, ST13 and HSP40 facilitate hGR binding to HSP90 and HOP in an energy dependent fashion. This complex is stabilised by immunophillins FKBP 51, FKBP59, CYP40 and P23 and is necessary for the hGR to be able to bind GC. The ATPase BAG1 can function as negative regulator of HSP70, and may downregulate hGR activity. After the GC-hGR complex is f

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