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Dissertations / Theses on the topic 'HSP32'

Author: Grafiati

Published: 4 June 2021

Last updated: 11 February 2022

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1

Almeida, Breno Fernando Martins de. "O papel da heme oxigenase-1 na leishmaniose visceral canina /." Araçatuba, 2016. http://hdl.handle.net/11449/143430.

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Orientador: Valéria Marçal Felix de Lima<br>Coorientador: Paulo César Ciarlini<br>Banca:Luiz Daniel de Barros<br>Banca:Flavia Lombardi Lopes<br>Banca:Suely Regina Mogami Bomfim<br>Banca; Rosimeri de Oliveira Vasconcelos<br>Resumo: A leishmaniose visceral canina (LVC) é uma doença crônica que causa imunossupressão nos animais doentes, principalmente por prejudicar a resposta imunológica celular, diminuindo a proliferação linfocitária e a capacidade fagocítica das células de defesa. Recentemente, a enzima heme oxigenase-1 (HO-1) vem ganhando destaque por estar envolvida na regulação da resposta

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2

Ireland, H. Elyse. "Hsp72 modulation of inflammatory immune responses." Thesis, University of Chester, 2009. http://hdl.handle.net/10034/76354.

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The body initiates an immune response to danger signals. The Danger model of the immune system postulates that danger signals are produced by exogenous molecules from foreign invaders, such as bacteria, and endogenous molecules released from damaged or injured cells. The response involves antigen recognition leading to up-regulation of cytokines and cell surface markers, followed by the recruitment of antigen presenting cells and T-helper cells which determine how the immune system responds. Endogenous danger signals include Hsp72 and HMGB-1. This thesis describes the development of specific a

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3

Williams, Helen. "Interactions between extracellular Hsp72 and blood cells." Thesis, University of Chester, 2010. http://hdl.handle.net/10034/277691.

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In recent years, compelling evidence has accumulated suggesting heat shock proteins (HSPs) which are generally believed to be localised and functioning mainly within eukaryotic cells as cyto-protective molecular chaperones, are also localised in the extracellular milieu. Depending on their localisation, on the cell surface (membrance-bound or embedded), or in the peripheral circulation, extracellular HSPs may induce apoptotic cell death, or in contrast protect cells from cell damage and/or cell death when exposed to cellular stress, or may even elicit a stimulatory effect on the innate immune

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4

Kelly, David A. "Antioxidant depletion limits induction of HSP72 following exercise." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp02/NQ31146.pdf.

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5

Quigley, Paulene. "Structural studies of the chaperone Hsp31 from Escherichia coli /." Thesis, Connect to this title online; UW restricted, 2003. http://hdl.handle.net/1773/8696.

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6

COSTA, A. C. T. "Resposta a Estresses Consecutivos em Saccharomyces Cerevisiae." Universidade Federal do Espírito Santo, 2017. http://repositorio.ufes.br/handle/10/7103.

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Made available in DSpace on 2018-08-01T21:35:00Z (GMT). No. of bitstreams: 1 tese_10830_Dissertação_Ane Catarine Tosi Costa.pdf: 1708151 bytes, checksum: 864bf59fdffed1b6179cb9c87c5f7593 (MD5) Previous issue date: 2017-03-09<br>A levedura Saccharomyces cerevisiae desempenha um papel importante na indústria, devido a sua alta capacidade fermentativa. Durante a fermentação há mudanças constantes nas condições do meio, expondo as leveduras a uma série de estresses simultâneos ou sequenciais e uma adaptação eficiente pode levar a aumento da produtividade e um consequente aperfeiçoamento do seu d

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7

Perreault, Karine. "Effet de l’entraînement en résistance sur un nouveau biomarqueur de sarcopénie : la protéine plasmatique HSP72 (eHSP72)." Mémoire, Université de Sherbrooke, 2014. http://hdl.handle.net/11143/5426.

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La sarcopénie (faible masse musculaire) est associée à l’inflammation silencieuse et à une augmentation du risque d’incapacité physique chez la population vieillissante. Une des interventions non pharmacologiques les mieux appuyées scientifiquement pour ralentir la sarcopénie est l’entraînement en résistance. Pour être en mesure de dépister la sarcopénie et évaluer l’efficacité des interventions qui s’y adressent, nous avons besoin d’outils qui permettent de quantifier la masse musculaire. Bien qu’elles soient issues de technologies avancées, les techniques d’imagerie actuelles quantifi

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8

Mujacic, Mirna. "Characterization of regulation and expression patterns of Escherichia coli Hsp31 protein /." Thesis, Connect to this title online; UW restricted, 2006. http://hdl.handle.net/1773/8119.

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9

Leoni, Francesca. "Hsp72 translocation and secretion in in vivo and in vitro models." Thesis, University of Chester, 2009. http://hdl.handle.net/10034/93835.

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Evidence suggesting that Hsp72 is actively participating in cellular signalling as well interacting with immune system dynamics has been increasing. This is true in healthy, stressed and diseased cells but to different degrees. Modulation of the plasma membrane association and secretion in the extracellular environment by different types of stressors is the key event that leads to different degrees of immune system activation. Hence a better understanding of the mechanisms of Hsp72 secretion and association with plasma membrane is crucial. This thesis investigated the tissue source and mechani

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10

LEONI, Nicole de Melo. "Modulação dietética utilizando lipídios e resveratrol na senescência e formação do pufe Hsp22 em Drosophila melanogaster." Universidade Federal de Pernambuco, 2012. https://repositorio.ufpe.br/handle/123456789/12408.

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Submitted by Luiz Felipe Barbosa (luiz.fbabreu2@ufpe.br) on 2015-03-13T13:11:59Z No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) Dissertação Nicole Leoni numerada.pdf: 2611677 bytes, checksum: e5bacea1c2ee6c31edf71b1c3cf3df25 (MD5)<br>Made available in DSpace on 2015-03-13T13:11:59Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) Dissertação Nicole Leoni numerada.pdf: 2611677 bytes, checksum: e5bacea1c2ee6c31edf71b1c3cf3df25 (MD5) Previous issue date: 2012<br>Os efeitos do resveratrol e

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LEONI, Nicole de Melo. "Modulação dietética utilizando lipídios e resveratrol na senescência e formação do pufe Hsp22em Drosophila melanogaster." Universidade Federal de Pernambuco, 2012. https://repositorio.ufpe.br/handle/123456789/18525.

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Submitted by Caroline Falcao (caroline.rfalcao@ufpe.br) on 2017-04-10T16:45:24Z No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) 2012-Dissertação-NicoleLeoni.pdf: 2611853 bytes, checksum: 64bb3c5f2ca3ff1fd9b70a9e02babd6d (MD5)<br>Made available in DSpace on 2017-04-10T16:45:24Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) 2012-Dissertação-NicoleLeoni.pdf: 2611853 bytes, checksum: 64bb3c5f2ca3ff1fd9b70a9e02babd6d (MD5) Previous issue date: 2012<br>Os efeitos do resveratrol e da utilização de

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12

Lucas, Mark. "Modulation of apoptosis by HSP72 in human myeloid leukaemia and endothelial cells." Thesis, University of Warwick, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.343124.

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13

Simar, David. "Expression de Hsp72 au cours du vieillissement : quel rôle pour l'aptitude physique ?" Montpellier 1, 2004. http://www.theses.fr/2004MON14003.

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Ce travail de these s'est interesse a l'etude de l'expression de hsp72 au cours du vieillissement et aux effets de l'activite physique sur la capacite d'induction de cette proteine chez les personnes agees. Les personnes agees sont caracterisees par une baisse de la capacite de l'organisme a repondre de maniere adaptee a des conditions agressives et ce phenomene pourrait etre lie, au niveau cellulaire, a une alteration de la capacite d'induction de hsp72. Chez les sujets jeunes, il a ete observe qu'une aptitude physique aerobie elevee etait associee a une capacite d'induction de cette proteine

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14

Mukwevho, Emmanuel. "The isolation and characterization of heat shock protein Hsp12 in Lipomyces starkeyi." Master's thesis, University of Cape Town, 2002. http://hdl.handle.net/11427/10953.

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Bibliography: leaves 60-72.<br>The stress response protein Hsp 12 is induced in S. cerevisiae cells upon exposure to salt stress, heat shock, ethanol, and upon entry to stationary phase (Mtwisha et aI., 1998). In this study, the occurrence of proteins related to Hsp12 was investigated in a number of yeasts (namely, Saccharomyces cerevisiae S288C, Schizosaccharomyces pombe, Debaromyces hansenii, Lipomyces starkeyi Y-2024, Saccharomyces cerevisiae IFO 23X7 (Kaokai), Zygosaccharomyces rouxii and Pichia sorbitophila. This was performed by selective protein extraction followed by SDS-P AGE and west

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15

Mills, Ross Jack. "Autoantibodies in ILD : detection and association of anti-Hsp72 IgG complexes in IPF." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/29615.

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Background Idiopathic pulmonary fibrosis (IPF) is one of a number of interstitial lung diseases (ILDs) that result in extensive and chronic pulmonary fibrosis. In IPF pathology, immunological dysfunction has been identified as a contributing factor to the ongoing fibrotic process, implicating cells and mechanisms of both the innate and humoral immune response. Due to the complex and diverse range of cells and mediators involved in IPF, the pathology is still poorly understood. Evidence of complement activation through the classical pathway in IPF lungs implies a role for IgG in the pathology.

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16

Carsillo, Thomas John. "A role for the major inducible 70 KDA heat shock protein (HSP72) in experimental measles encephalitis." Columbus, Ohio : Ohio State University, 2006. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1141316578.

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17

Tsekoa, Tsepo. "Investigating the role of a yeast membrane protein, HSP30 in tolerance to ethanol stress." Master's thesis, University of Cape Town, 2001. http://hdl.handle.net/11427/4342.

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Bibliography: leaves 59-64.<br>One of the contributors of the widespread interest the yeast Saccharomyces cerevisiae has received is its ability to yield and tolerate high levels of ethanol. S. cerevisiae is able to grow and remain viable in growth media containing ethanol concentrations as high as 19.8% (w/v), a level that is toxic to many other microorganisms. Since production of ethanol is a normal event in the growth cycyle of S. cerevisiae, this organisms has evolved a number of mechanisms to cope with deleterious effects of ethanol. These include induction of heat shock proteins (HSPs).

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18

Mulligan, Tuttle Anne. "Characterization of the expression and function of Rana catesbeiana HSP30 and Xenopus laevis HSP27." Thesis, University of Waterloo, 2006. http://hdl.handle.net/10012/1214.

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Exposure of cells to environmental or chemical stressors will initiate the heat shock response, which is mediated by heat shock proteins. Heat shock proteins are molecular chaperones which are classified by size into six main families: HSP100, HSP90, HSP70, HSP60, HSP40 and the small heat shock proteins (sHsps). The sHsp family members bind to denatured proteins and maintain them in a folding competent state such that they may be refolded by other molecular chaperones. <br /><br /> The present study examined the expression and function of two amphibian sHsps, namely, <em>Rana catesbeia

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19

Léger, Antoine. "Production, purification et caractérisation de la protéine Hsp 12 de Saccharomyces cerevisiae, une protéine impliquée dans la sucrosité du vin." Thesis, Bordeaux, 2019. http://www.theses.fr/2019BORD0232/document.

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La protéine Hsp12 est une protéine de choc thermique (12 kDa) exprimée par la levure Saccharomyces cerevisiae et associée à la réponse au stress. En effet, il a été montré que les transcrits du gène HSP12 sont exprimés en réponse à différents stress. De plus, la protéine Hsp12 serait responsable de la sucrosité du vin observée au cours de l’autolyse des levures lors de la vinification. Cependant, le goût sucré pourrait provenir de la protéine Hsp12 entière, ou, d’un ou plusieurs peptides issus de la protéine Hsp12. L’objectif de cette étude était d’obtenir la protéine Hsp12 native pure à parti

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20

Kim, Hyun-Ju. "Transcriptomic and proteomic studies on longevity induced by over-expression of HSP22 in drosophila melanogaster." Doctoral thesis, Québec : Université Laval, 2008. http://www.theses.ulaval.ca/2008/25824/25824.pdf.

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21

Long, Romain. "Implication des fonctions mitochondriales dans l'effet cardioprotecteur induit par la sur-expression de la protéine H11 kinase/Hsp22 chez la souris." Thesis, Paris 11, 2014. http://www.theses.fr/2014PA114809/document.

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La reperméabilisation par thrombolyse, angioplastie ou chirurgie cardiaque des artères coronaires au décours d’un épisode d’ischémie myocardique est à l’origine d’une réduction spectaculaire de la morbi-mortalité de l’insuffisance coronaire aiguë. Elle est cependant la cause de lésions supplémentaires. La recherche de nouvelles approches cardioprotectrices complémentaires des méthodes de reperfusion actuelles est donc indispensable pour réduire les conséquences de l’ischémie myocardique. La découverte de puissants mécanismes cardioprotecteurs endogènes qui consistent en de brefs épisodes d’isc

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22

Neubert, Jonathan Paul. "Characterizing the Role of HspB2 in Cardiac Metabolism and Muscle Structure Using Yeast and Mammalian Systems." BYU ScholarsArchive, 2012. https://scholarsarchive.byu.edu/etd/3748.

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HspB2 is a small heat shock protein encoded on human chromosome 11. Less than 1000 base pairs away from HSPB2 and situated in a head-to-head orientation lies the gene encoding another small heat shock protein, CRYAB. Because they are uncommonly close to one another they share regulatory elements. In addition, they share protein homology as sHSPs, suggesting that they perhaps perform aimilar functions. SHSPs such as HspB2 and CryAB are traditionally thought to provide protective effects to cells in response to a variety of stress inducers. In response to stress they form complexes around misfol

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23

Adaui, Vanessa, Constanze Kröber-Boncardo, Christine Brinker, et al. "Application of crispr/cas9-based reverse genetics in leishmania braziliensis: Conserved roles for hsp100 and hsp23." MDPI AG, 2020. http://hdl.handle.net/10757/655510.

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The protozoan parasite Leishmania (Viannia) braziliensis (L. braziliensis) is the main cause of human tegumentary leishmaniasis in the New World, a disease affecting the skin and/or mucosal tissues. Despite its importance, the study of the unique biology of L. braziliensis through reverse genetics analyses has so far lagged behind in comparison with Old World Leishmania spp. In this study, we successfully applied a cloning-free, PCR-based CRISPR–Cas9 technology in L. braziliensis that was previously developed for Old World Leishmania major and New World L. mexicana species. As proof of princip

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24

Hottinger, Shawna KB. "Mimicking αB crystallin phosphorylation at serine 45 and 59 in vivo". University of Cincinnati / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1242921753.

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25

Zoppi, Claudio Cesar. "Efeitos do treinamento e do overtraining no metabolismo oxidativo, enzimas antioxidantes e HSP72 em diferentes fibras musculares." [s.n.], 2004. http://repositorio.unicamp.br/jspui/handle/REPOSIP/314083.

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Orientador: Denise Vaz de Macedo<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-03T21:16:39Z (GMT). No. of bitstreams: 1 Zoppi_ClaudioCesar_D.pdf: 3992666 bytes, checksum: e8868a527d2a2640dbb8ec1f303e49d4 (MD5) Previous issue date: 2004<br>Resumo: O treinamento físico induz uma série de adaptações no organismo que leva à melhora na performance esportiva. No entanto, os atletas podem ser submetidos a cargas extremamente altas de treinamento e quando a recuperação não é suficiente este atleta pode ser acometido pelo overtra

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26

Kleinsmidt, Leela S. "The effect of osmotic stress and HSP12 on passive and active transport in the Yeast Saceharomyces cervisiae." Master's thesis, University of Cape Town, 2010. http://hdl.handle.net/11427/4281.

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Zhang, Xinsheng. "Structural and functional interactions between measles virus nucleocapsid protein and cellular heat shock protein." Connect to this title online, 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1078417800.

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Thesis (Ph. D.)--Ohio State University, 2004.<br>Title from first page of PDF file. Document formatted into pages; contains xv, 155 p.; also includes graphics (some col.) Includes bibliographical references (p. 147-155). Available online via OhioLINK's ETD Center

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Marshall, Helen C. "Physiological and Hsp72 responses of human males to acute and repeated exposures to exercise in a humid heat." Thesis, University of Strathclyde, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.431806.

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29

Muller, Carlos Henrique de Lemos. "Resposta ao choque térmico e da razão HSPA1A extra/intracelular em leucócitos de indivíduos idosos e de meia idade submetidos a treinamento de força." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2018. http://hdl.handle.net/10183/174954.

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Justificativa: O processo de envelhecimento está associado com o aumento demasiado na produção das espécies reativas de oxigênio (EROS). Dentre as estratégias que as células desenvolveram ao longo da evolução para combater o estresse celular, destacam-se as proteínas de choque térmico (HSP). Em especial, a HSPA1A (HSP72) é importante para recuperação de proteínas danificadas, impedindo a agregação das mesmas no citoplasma. O processo de envelhecimento parece estar associado a um declínio nos níveis das HSPs, resultando na perda do controle da proteostase, atrofia muscular, resistência à insuli

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30

Cremers, Claudia [Verfasser], Johannes [Akademischer Betreuer] Buchner, and Ursula [Akademischer Betreuer] Jakob. "Functional and structural characterization of the redox regulated chaperone Hsp33 / Claudia Cremers. Gutachter: Ursula Jakob ; Johannes Buchner. Betreuer: Johannes Buchner." München : Universitätsbibliothek der TU München, 2012. http://d-nb.info/1038527228/34.

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Welker, Sylvia [Verfasser], Johannes [Akademischer Betreuer] Buchner, and Sevil [Akademischer Betreuer] Weinkauf. "Hsp12: Funktion und Struktur eines nativ ungefalteten Proteins aus S. cerevisiae / Sylvia Welker. Gutachter: Sevil Weinkauf ; Johannes Buchner. Betreuer: Johannes Buchner." München : Universitätsbibliothek der TU München, 2009. http://d-nb.info/1054654387/34.

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Smolka, Marcus Bustamante. "Exercicio fisico e expressão da proteina de estresse HSP72 em musculos de ratos submetidos a diferentes a diferentes tipos de treinamento." [s.n.], 1999. http://repositorio.unicamp.br/jspui/handle/REPOSIP/314374.

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Orientador: Jose Camillo Novello<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-07-24T19:11:57Z (GMT). No. of bitstreams: 1 Smolka_MarcusBustamante_M.pdf: 4832023 bytes, checksum: dfb889ff5d8318e0548d4316a215b124 (MD5) Previous issue date: 1999<br>Resumo: O músculo é um tecido dotado de grande plasticidade, isto é, tem a capacidade de alterar suas características bioquímicas e funcionais para melhor se adaptar frente a variados estímulos. O exercício físico pode promover estímulos que induzem adaptações no sistema de p

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33

Ecochard, Laurent. "Influence des modifications d'activité contractile et des altérations du potentiel de phosphorylation sur l'expression de la protéine de choc thermique Hsp72." Lyon 1, 2000. http://www.theses.fr/2000LYO10207.

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34

Bruel, Nicolas. "Hsp33 controls elongation factor-tu stability and allows escherichia coli growth in the absence of the major dnak and triggerfactor chaperones." Toulouse 3, 2013. http://thesesups.ups-tlse.fr/2098/.

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Le repliement intracellulaire des protéines nouvellement synthétisées est assisté par des réseaux cellulaires de protéines chaperons. Chez Escherichia coli, la coopération entre les protéines chaperons Trigger Factor (TF) et DnaK est prédominante dans ce processus. En accord avec ceci, la délétion simultanée des gènes codants pour ces deux protéines chaperons conduit à une croissance bactérienne très réduite et à l'accumulation d'un grand nombre de protéines cytoplasmiques sous forme d'agrégats. Au cours de cette étude, nous avons utilisé ces phénotypes afin de mettre en évidence des interacti

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35

Regnacq, Matthieu. "Etude d'un nouveau gène heat shock dont l'expression est associée à l'entrée en phase stationnaire chez la levure saccharomyces cerevisiae : le gène HSP30." Bordeaux 2, 1992. http://www.theses.fr/1992BOR28213.

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Rénier, Wendy. "Implication de deux protéines de choc thermique humaines HSP70 et HSP22 dans les voies de la réparation de l'ADN : approche structurale et fonctionnelle." Université Joseph Fourier (Grenoble), 2006. http://www.theses.fr/2006GRE10182.

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HSP22 et HSP70 sont des protéines d'origine humaine appartenant à la famille des Heat Shock Proteins. Cette thèse décrit des travaux visant à déterminer l'implication de ces deux protéines humaines de choc thermique HSP70 et HSP22, dans les voies de réparation de l'ADN après stress. Ces protéinespossèdent, comme leur nom le sous-entend, la capacité d'être surexprimées par la cellule après choc thermique mais aussi après une grande variété d'autres stress et dans de nombreuses maladies (Tavaria M et al, 1996). Pour mieux connaître ces protéines, une étude structurale a été initiée. Les structur

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Levada, Kateryna [Verfasser], Andreas Akademischer Betreuer] Ludwig, Pavel [Akademischer Betreuer] Strnad, and Gabriele [Akademischer Betreuer] [Pradel. "Hsp72 overexpression protects from APAP and MCD induced liver injury via attenuation of JNK signalling / Kateryna Levada ; Andreas Ludwig, Pavel Strnad, Gabriele Pradel." Aachen : Universitätsbibliothek der RWTH Aachen, 2016. http://d-nb.info/1129876152/34.

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Hoopes, Whitney Katherine. "A CryAB Interactome Reveals Clientele Specificity and Dysfunction of Mutants Associated with Human Disease." BYU ScholarsArchive, 2016. https://scholarsarchive.byu.edu/etd/6576.

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Small Heat Shock Proteins (sHSP) are critical molecular chaperones that function to maintain protein homeostasis (proteostasis) and prevent the aggregation of other proteins during cellular stress. Any disruption in the process of proteostasis can lead to prevalent diseases ranging from cancer and cataract to cardiovascular and Alzheimer's disease. CryAB (αB-crystallin, HspB5) is one of ten known human sHSP that is abundant in the lens, skeletal, and cardiac muscle. This protein is required for cardiac function and muscle cell integrity. When the cell experiences physiological stress, includin

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Langston, Kelsey Murphey. "Identification of the Binding Partners for HspB2 and CryAB Reveals Myofibril and Mitochondrial Protein Interactions and Non-Redundant Roles for Small Heat Shock Proteins." BYU ScholarsArchive, 2013. https://scholarsarchive.byu.edu/etd/3822.

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Small Heat Shock Proteins (sHSP) are molecular chaperones that play protective roles in cell survival and have been shown to possess chaperone activity. As such, mutations in this family of proteins result in a wide variety of diseases from cancers to cardiomyopathies. The sHSPs Beta-2 (HspB2) and alpha-beta crystalline (CryAB) are two of the ten human sHSPs and are both expressed in cardiac and skeletal muscle cells. A heart that cannot properly recover or defend against stressors such as extreme heat or cold, oxidative/reductive stress, and heavy metal-induced stress will constantly struggle

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Lakhdari, Nadjem. "Programmation néonatale de l’infertilité mâle : rôle de la dérégulation de l’expression des microARNs dans l’apoptose des cellules germinales." Thesis, Paris 11, 2013. http://www.theses.fr/2013PA11T096/document.

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Un certain nombre d’études épidémiologiques font état d’une augmentation de l’infertilité masculine durant ces cinquante dernières années, en particulier dans les pays industrialisés, mais aussi d’une augmentation des malformations de l’appareil reproducteur masculin telles que la cryptorchidie (absence de migration des testicules dans les bourses) ou l’hypospadias (malformation du pénis), et des cancers testiculaires. Des données expérimentales suggèrent que ces anomalies du tractus génital mâle sont liées. Ces symptômes forment le syndrome de dysgénésie testiculaire. Les causes d’apparition

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41

Buccellato, Matthew Allan. "Host-mediated Alteration of Measles Virus Polymerase Activity: Consequences for the Outcome of Infection." Columbus, Ohio : Ohio State University, 2008. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1210961676.

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Chalmin, Fanny. "Rôles des cellules myéloïdes suppressives et des lymphocytes Th17 dans le cancer." Thesis, Dijon, 2012. http://www.theses.fr/2012DIJOMU01.

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Le système immunitaire joue un double rôle dans le cancer: il peut non seulement supprimer la croissance tumorale en détruisant les cellules cancéreuses, mais aussi promouvoir la progression de la tumeur en sélectionnant les cellules tumorales ou en créant un microenvironnement tumoral immunosuppresseur. Au cours de ma thèse, je me suis intéressée à deux populations du système immunitaire : les MDSC (Myeloïd Derived Suppressor Cells) et les lymphocytes Th17. Dans ce travail, nous avons exploré les mécanismes impliqués dans l’activation et dans les fonctions suppressives de ces deux populations

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43

LUNZ, W. "L-NAME aumenta a expressão de proteínas de estresse (Hsp72) induzida pelo exercício físico e altera a dinâmica de contração-relaxamento de cardiomiócitos isolados do ventrículo esquerdo de ratos." Universidade Federal do Espírito Santo, 2010. http://repositorio.ufes.br/handle/10/8035.

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Made available in DSpace on 2018-08-01T22:59:14Z (GMT). No. of bitstreams: 1 tese_4488_Tese Welinton Lunz - 2010.pdf: 1070969 bytes, checksum: 39fc19505e0fb4aa0c92e005788ed147 (MD5) Previous issue date: 2010-12-16<br>L-NAME Aumenta a Expressão de Proteínas de Estresse (Hsp72) Induzida pelo Exercício Físico e Altera a Dinâmica de Contração-Relaxamento de Cardiomiócitos Isolados do Ventrículo Esquerdo de Ratos. Introdução. O exercício físico aumenta tanto a expressão da chaperona Hsp72 quanto a biodisponibilidade de óxido nítrico (NO) no miocárdio. Estudos sugerem que o NO modula a expres

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44

Zemska, Olga. "Discovery Of Intracellular Growth Requirements of the Fungal Pathogen Histoplasma capsulatum." The Ohio State University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=osu1343803044.

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Servais, Stéphane. "Altérations mitochondriales et stress oxydant pulmonaire en réponse à l'ozone : Effets de l'âge et d'une supplémentation en oméga-3." Phd thesis, Université Claude Bernard - Lyon I, 2004. http://tel.archives-ouvertes.fr/tel-00012031.

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L'ozone (O3) est l'une des espèces moléculaires les plus réactives auxquelles sont exposés les êtres vivants. L'O3 agit essentiellement au niveau du système pulmonaire par l'intermédiaire d'un stress oxydatif. Parce que la susceptibilité au stress oxydant varie avec l'âge, nous avons étudié les altérations de l'équilibre pulmonaire entre production des dérivés réactifs de l'O2 (ROS) et leur élimination, chez des rats immatures (21 jours), adultes (6 mois) et âgés (20 mois) lors d'une exposition à l'O3 (0,5 ppm, 12 heures/jour pendant 7 jours). Pour cela nous nous sommes particulièrement intére

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46

Braga, Ana Claudia Silva [UNESP]. "Regulação da expressão de proteínas de choque térmico pelo vírus da hepatite C." Universidade Estadual Paulista (UNESP), 2017. http://hdl.handle.net/11449/151515.

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Submitted by ANA CLAUDIA SILVA BRAGA null (anabragga@gmail.com) on 2017-08-31T16:15:53Z No. of bitstreams: 1 Tese Doutorado Ana Claudia Silva Braga.pdf: 4552779 bytes, checksum: 456de4a6fbfd60347292d8755d6c8c47 (MD5)<br>Approved for entry into archive by Luiz Galeffi (luizgaleffi@gmail.com) on 2017-09-01T14:16:37Z (GMT) No. of bitstreams: 1 braga_acs_dr_sjrp.pdf: 4552779 bytes, checksum: 456de4a6fbfd60347292d8755d6c8c47 (MD5)<br>Made available in DSpace on 2017-09-01T14:16:37Z (GMT). No. of bitstreams: 1 braga_acs_dr_sjrp.pdf: 4552779 bytes, checksum: 456de4a6fbfd60347292d8755d6c8c47 (MD5)

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Lakhdari, Nadjem. "Programmation néonatale de l'infertilité mâle : rôle de la dérégulation de l'expression des microARNs dans l'apoptose des cellules germinales." Phd thesis, Université Paris Sud - Paris XI, 2013. http://tel.archives-ouvertes.fr/tel-01061771.

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Un certain nombre d'études épidémiologiques font état d'une augmentation de l'infertilité masculine durant ces cinquante dernières années, en particulier dans les pays industrialisés, mais aussi d'une augmentation des malformations de l'appareil reproducteur masculin telles que la cryptorchidie (absence de migration des testicules dans les bourses) ou l'hypospadias (malformation du pénis), et des cancers testiculaires. Des données expérimentales suggèrent que ces anomalies du tractus génital mâle sont liées. Ces symptômes forment le syndrome de dysgénésie testiculaire. Les causes d'apparition

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Smith, Simone Marsha-Lee. "The proteoglycan perlecan regulates long bone growth through interactions with developmental proteins in the growth plate." [Tampa, Fla.] : University of South Florida, 2007. http://purl.fcla.edu/usf/dc/et/SFE0002155.

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Degenhardt, Ulrike [Verfasser]. "Immunhistochemische Charakterisierung nicht-melanozytärer Hauttumore anhand mono- und polyklonaler Antikörper der Hitze-Schock-Proteine HSP27, HSP32, HSP70, HSP72, HSP73 und Metallothionein / vorgelegt von Ulrike Degenhardt." 2003. http://d-nb.info/971601615/34.

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Cheng, Ya-Fang, and 鄭雅方. "Modulatory Effects of Multimodality Stimulation at Neiguan (PC 6) on Myocardial Hsp32 Expression in Rats." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/5w75r2.

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碩士<br>國立陽明大學<br>傳統醫藥學研究所<br>97<br>Hsp32 is a stress-inducible protein with prominent cardio-protective functions. The aim of this study was to investigate the effect of multimodality stimulations at acupoint PC 6 on myocardial Hsp32 expression in rats. Male Sprague-Dawley rat, weighing 260~320g, were divided into six groups, namely, lectroacupuncture group (EA), laser acupuncture group (LA), hydroacupuncture group (HA), local somatothermal stimulation group (LSTS), sham group (for EA, LA, LSTS) and normal group (for HA), under adequate anesthesia, multimodalities, such as EA, LA, HA and LSTS w

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