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Dissertations / Theses on the topic 'HSVC'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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1

Jayavaradhan, Rajeswari. "Optimization of Gene Editing Approaches for Human Hematopoietic Stem Cells." University of Cincinnati / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1543919940219677.

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David, Dylan Naitraj. "Inflammation-Induced HSPC Dysfunction: Towards a Better Understanding of the Role of MAVS, ASC, and Caspase-1 in HSPC Dysfunction and Bone Marrow Failure." University of Cincinnati / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1626356668978688.

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3

Pongsacharoennont, Oneta. "Today's Intelligence Banking : (Case study HSBC Thailand)." Thesis, Mälardalen University, School of Sustainable Development of Society and Technology, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-871.

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4

Šperlich, Marek. "Analýza efektivity tréninkového programu v bance HSBC." Master's thesis, Vysoká škola ekonomická v Praze, 2008. http://www.nusl.cz/ntk/nusl-9350.

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The thesis theme is research and analysis of training program in HSBC Bank which took place during September 2007. The thesis is divided in to five chapters. The first chapter is devoted to theory of andragogics, corporate training and efficiency analysis. The second chapter is devoted to empirical research also problem and its solution is introduced there. The third chapter introduces HSBC Bank and HSBC Bank training program. This training program was created for newly hired employees. The fourth chapter consist of three surveys of participators of this training. The first -questionary- is fo

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Öman, Tommy. "Multivariate Analysis of 2D-NMR Spectroscopy : Applications in wood science and metabolomics." Doctoral thesis, Umeå universitet, Kemiska institutionen, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-80201.

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Wood is our most important renewable resource. We need better quality and quantity both according to the wood itself and the processes that are using wood as a raw material. Hence, the understanding of the chemical composition of the wood is of high importance. Improved and new methods for analyzing wood are important to achieve better knowledge about both refining processes and raw material. The combination of NMR and multivariate analyses (MVA) is a powerful method for these analyses but so far it has been limited mainly to 1D NMR. In this project, we have developed methods for combining 2D

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6

Caligiuri, Kyle. "Investigation of the deregulated miRNome identified during acute viral infections in a murine model of HSV-1 encephalitis." Springer Science+Business Media, LLC, 2013. http://hdl.handle.net/1993/23926.

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Herpes simplex virus type 1 (HSV-1) is a double stranded DNA virus that causes epithelial skin infections and persists through the life of the host by infecting neurons, where it can switch to a latent state to evade an immune response. In rare cases during primary infection or after reactivation, instead of undergoing lytic infection at the epithelial surface, it instead travels to the brain and causes herpes simplex virus encephalitis (HSVE) which can have a ≥70% mortality rate if untreated. As the virus takes over its host cell, it gains control of the host cell machinery and manipulates

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7

Reeder, John. "Hilbert Space Filling Curve (HSFC) Nearest Neighbor Classifier." Honors in the Major Thesis, University of Central Florida, 2005. http://digital.library.ucf.edu/cdm/ref/collection/ETH/id/794.

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This item is only available in print in the UCF Libraries. If this is your Honors Thesis, you can help us make it available online for use by researchers around the world by following the instructions on the distribution consent form at http://library.ucf<br>Bachelors<br>Engineering and Computer Science<br>Computer Engineering

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8

Poccardi, Nolwenn. "Etude du contrôle de l’etablissement de l’infection latente de HSV1 et de sa capacité de réactivation." Thesis, Université Paris-Saclay (ComUE), 2017. http://www.theses.fr/2017SACLS148.

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Le virus Herpes Simplex de type 1 (HSV1) est responsable chez l’homme, son seul hôte naturel, d’infections oculaires cornéennes (kératites) récurrentes, typiquement unilatérales, pouvant induire une perte majeure de la vision. Pendant toute la vie, le virus reste à l’état quiescent (latence) dans le système nerveux, en particulier dans les deux ganglions trigéminés (TG) qui sont responsables de l’innervation sensitive de la cornée. La réactivation du virus à partir de ces TG entraine la kératite. Jusqu’à présent, les seuls traitements disponibles contre HSV1 ne sont que curatifs, c’est à dire

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Rousseau, Antoine. "Cinétique des effecteurs immunologiques impliqués dans la protection contre le virus Herpès simplex type 1 (HSV1) après primo-infection par une autre souche non neurovirulente : vers un modèle vaccinal." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLS339.

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Chez l’homme, la primo-infection par le vírus Herpès simplex de type 1 (HSV-1) a lieu au niveau de la muqueuse oro-pharyngée. Après une phase de réplication, les virions pénètrent les terminaisons axonales et migrent vers le ganglion trijumeau ipsilatéral (TG), puis vers le TG controlatéral. Le virus entre alors dans un état de latence dans les 2 TG. Les réactivations d’HSV-1 dans ces neurones sont responsables des kératites herpétiques (KH), unilatérales et survenant toujours du même côté chez un patient donné.En utilisant un modèle murin oro-oculaire, qui reproduit les aspects essentiels de

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10

Stein, Sebastian [Verfasser]. "HSC-Kantenbearbeitung von Blech / Sebastian Stein." Aachen : Shaker, 2010. http://d-nb.info/1081884592/34.

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11

Dyer, Angela Patricia. "Characterization of HSV glycoprotein-glycosaminoglycan interactions." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0026/NQ50304.pdf.

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12

QUARANTA, PAMELA. "Unveiling the biological role of human circulating Hematopoietic Stem and Progenitor cells." Doctoral thesis, Università Vita-Salute San Raffaele, 2022. http://hdl.handle.net/20.500.11768/128257.

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Although mostly resident in the bone marrow (BM), few circulating HSPC (cHSPC) regularly traffic in the peripheral blood (PB) of un-mobilized subjects. Mainly descriptive studies have been published so far about this rare population in humans, and a complete evaluation of their composition, functional features and hierarchical relationship with respect to BM HSPC is still missing. In the present study, we phenotypically characterized cHSPC composition during aging, by applying multi-parametric flow cytometry on 114 PB and, as control, 48 BM samples of healthy donors (HD) of diverse age. These

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Hutchinson, Lloyd M. "Glycoprotein K of herpes simplex virus (HSV), role in viral egress and HSV-induced cell-cell fusion." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0016/NQ30094.pdf.

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14

Kinney, Emma. "Decoupling of HSV1 Vhs protein mRNA decay and translation stimulation." Thesis, University of Missouri - Kansas City, 2013. http://pqdtopen.proquest.com/#viewpdf?dispub=1543940.

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<p> Herpes Simplex Virus Type 1 is a member of the <i>alphaherpesvirinae </i> subfamily within the family <i>Herpesviridae</i>. This virus has both a lytic and latent cycle. Primary infection occurs when the virus enters epithelial cells around the mucosal lining of the nose and mouth. Within the epithelial cells, the virus undergoes an active lytic infection, causing an ulcerated blister, more famously known as a 'cold sore' or 'fever blister'. Once HSV enters the nearby sensory neurons the genome is transported to the neuronal cell body where its latency associated transcripts are activated

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Alanazi, Yousef Nifaj. "HSV-1 Replication in different RAW 264.7 and J774.1 macrophage Phenotypes and Macrophage viability following HSV-1 infection." Wright State University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=wright1525211483024617.

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Mulaudzi, Takalani. "An investigation of the zinc binding characteristics of the RING finger domain from the human RBBP6 protein using heteronuclear NMR spectroscopy." Thesis, University of the Western Cape, 2007. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_9063_1260173635.

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<p> <p>&nbsp<br></p> </p> <p align="left">Retinoblastoma binding protein 6 (RBBP6) is a 250 kDa human splicing-associated protein that is also known to interact with tumour suppressor proteins p53 and pRb and to mediate ubiquitination of p53 via its interaction with Hdm2. RBBP6 is highly up regulated in oesophageal cancer, and has been shown to be a promising target for immunotherapy against the disease. RBBP6 is also known to play a role in mRNA splicing, cell cycle control and apoptosis.</p>

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SCARFÒ, REBECCA. "Precise characterization of hemogenic endothelial cells during human hematopoietic development." Doctoral thesis, Università Vita-Salute San Raffaele, 2022. http://hdl.handle.net/20.500.11768/128259.

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During embryonic development, blood cells emerge from a subset of specialized endothelial cells, named hemogenic endothelium (HE), via a process known as endothelial-to-hematopoietic transition (EHT). HE represents a heterogeneous population found in various anatomical sites, including the yolk sac (YS) and the aorta-gonad-mesonephros (AGM). It comprises cells that differ in developmental potential, thus defining distinct hematopoietic programs. Despite the endothelial descendancy of blood cells is well established, the identity of HE is still debated. A more thorough characterization of HE is

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18

Krishna, Sudhir. "T cell recognition of HSV-1 glycoproteins." Thesis, University of Cambridge, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.317944.

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Yirrell, D. L. "Double infections with HSV in the mouse." Thesis, University of Bristol, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.234887.

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Al-Sulaiman, Abdulrahman. "Serological array for the diagnosis of viral infection of the central nervous system." Thesis, University of Manchester, 2010. https://www.research.manchester.ac.uk/portal/en/theses/serological-array-for-the-diagnosis-of-viral-infection-of-the-central-nervous-system(5c23bcf7-0679-437a-9617-342fc53e96d7).html.

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Encephalitis caused by the alphaherpes viruses HSV 1, HSV 2 and VZV can be devastating and rapid, accurate diagnosis is required. Whilst existing molecular techniques are invaluable in diagnosing acute disease, detection of antibody is needed to confirm infection and to make a diagnosis after the acute stage or during post-infectious encephalitis. Current immunoassays are limited by the volume of sample required. The aim of this project was to develop a rapid, accurate, low sample volume assay to improve diagnosis using Luminex technology.The immunodominant proteins of HSV and VZV, glycoprotei

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21

Brum, Patricia Leal de. "Da tv aberta à tv corporativa: o caso do banco HSBC." Universidade Tuiuti do Parana, 2012. http://tede.utp.br:8080/jspui/handle/tede/1495.

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Submitted by Divanete Paiva (divanete.paiva@utp.br) on 2018-08-01T13:05:08Z No. of bitstreams: 1 DA TV ABERTA.pdf: 121936601 bytes, checksum: 690afb7f076c8e54b3afeda326663afa (MD5)<br>Made available in DSpace on 2018-08-01T13:05:08Z (GMT). No. of bitstreams: 1 DA TV ABERTA.pdf: 121936601 bytes, checksum: 690afb7f076c8e54b3afeda326663afa (MD5) Previous issue date: 2012-08-31<br>This research aims to present the general theoretical and practical information to understand how is the dialogue between 'television commercial open' and 'corporate television', their adaptations and transpositions

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de, Fátima Pereira Lemos Verônica. "Glocal, global e local na publicidade o exemplo do caso HSBC." Universidade Federal de Pernambuco, 2009. https://repositorio.ufpe.br/handle/123456789/3170.

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Made available in DSpace on 2014-06-12T16:28:26Z (GMT). No. of bitstreams: 2 arquivo1921_1.pdf: 2103739 bytes, checksum: 2ad7ae88de5ff3bf650832ca85b9901f (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2009<br>Esta pesquisa é uma contribuição teórica às Ciências das Comunicações por meio de análise da produção publicitária contemporânea. Buscamos meios para elucidar um problema de pesquisa que se baseia na utilização de referências culturais locais de uma sociedade para transmitir ao público idéias de um mundo globalizado. Focando os me

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Singh, Rekha. "Cellular immune responses in HSV and CMV infections." Thesis, University of Ottawa (Canada), 2003. http://hdl.handle.net/10393/29036.

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The herpes simplex virus (HSV) and cytomegalovirus (CMV) are the prominent members of the Herpesviridae family collectively responsible for the majority of herpes-related morbidity and mortality in humans. These viruses are therefore the subjects of this study that was undertaken to improve our understanding of the nature of immune response and the mechanism of viral modulation leading to suppression of viral replication or evasion of the host immune response in vivo. The present study has examined the T helper responses to HSV-2 and murine CMV (MCMV) and provides new insights into the nature

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Klucken-Swyen, Heidi. "HSV/AAV-Hybridamplikonvektoren zur stabilen Transduktion humaner Zellen." Giessen : VVB Laufersweiler, 2007. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=016308696&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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Stylianou, Julianna. "Protein-protein interaction of HSV-1 tegument proteins." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/24663.

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Herpes simplex virus type 1 virions contain a proteinaceous layer between the nucleocapsid and the virus envelope termed the tegument. The mechanism underlying tegumentation remains largely undefined for all herpesviruses, as does the role of many tegument proteins in virus replication. The networks of protein interactions involved in virus assembly have been largely explored and although large-scale studies have been carried out using yeast two hybrid analyses of herpesvirus protein interactions, few of the identified networks have been validated in infected cells. Here, the molecular interac

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Meiklejohn, Stuart J. "The role of BMP signalling in HSC ontogeny." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:305597a8-b8cb-42ff-88fd-34b3dd5bf39b.

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The haematopoietic stem cell (HSC) is found in the adult human bone marrow, where it gives rise to all the circulating blood cells throughout adulthood. Understanding the signalling events that programme these cells during development will improve HSC in vitro culture, their generation from embryonic stem cells or induced pluripotent stem cells, and their potential therapeutic application. HSCs bud from the floor of the dorsal aorta and seed the bone marrow via circulation. The precursors to the dorsal aorta and HSCs are called haemangioblasts, which are found in the dorsal lateral plate mesod

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SIGHINOLFI, SILVIA. "INTRACELLULAR IRON OVERLOAD AFFECTS HSC METABOLISM BY IMPAIRING MITOCHONDRIAL FITNESS IN β-THALASSEMIA". Doctoral thesis, Università Vita-Salute San Raffaele, 2023. https://hdl.handle.net/20.500.11768/137019.

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Mitochondrial activity and metabolism significantly control hematopoietic stem cell (HSC) function and fate. HSCs change the metabolic state in response to stress signals, such as reactive oxygen species (ROS), which drive HSC entry into cell cycle accompanied by increased mitochondrial oxidative phosphorylation (OXPHOS) and glycolysis. However, excessive accumulation of ROS results in oxidative damage of cellular organelles, including mitochondria. Iron is one of the sources of ROS and HSCs can uptake iron but little is known about the effects of iron on HSC metabolism. Recently, we demonstr

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Ceschin, Michelle Beatriz Godoy Santos [UNESP]. "As estratégias discursivas da comunicação dirigida em pontos de venda do HSBC." Universidade Estadual Paulista (UNESP), 2006. http://hdl.handle.net/11449/89441.

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Made available in DSpace on 2014-06-11T19:24:03Z (GMT). No. of bitstreams: 0 Previous issue date: 2006-12-12Bitstream added on 2014-06-13T18:51:30Z : No. of bitstreams: 1 ceschin_mbgs_me_bauru.pdf: 1105426 bytes, checksum: 29d0a915a0a1860603ca4793a679ffc8 (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>O presente estudo tem como objeto a comunicação dirigida e investiga as estratégias discursivas da campanha “Triângulos” do HSBC no Brasil. São analisados os procedimentos enunciativos que regem a organização textual das peças publicitárias veiculada em folders

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Ceschin, Michelle Beatriz Godoy Santos. "As estratégias discursivas da comunicação dirigida em pontos de venda do HSBC /." Bauru : [s.n.], 2007. http://hdl.handle.net/11449/89441.

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Orientador: Ana SílviaLopes Davi Médola<br>Banca: Luciano Guimarães<br>Banca: Terezinha Fortes Mestrinelli<br>Resumo: O presente estudo tem como objeto a comunicação dirigida e investiga as estratégias discursivas da campanha "Triângulos" do HSBC no Brasil. São analisados os procedimentos enunciativos que regem a organização textual das peças publicitárias veiculada em folders disponibilizados nos pontos de venda das agências bancárias do HSBC, no final de 2004. O instrumental teórico-metodológico que baliza as reflexões aqui apresentadas é decorrente da semiótica discursiva de linha francesa,

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Colgrove, Julia S. "Polymorphic membrane protein expression in Chlamydia/HSV co-infected cells." Digital Commons @ East Tennessee State University, 2014. https://dc.etsu.edu/honors/241.

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The Chlamydiaceae are a bacterial family that contains a single genus: Chlamydia. The genus Chlamydia consists of 9 species that are obligate, intracellular pathogens. Untreated C. trachomatis infections can lead to serious health ramifications, such as ectopic pregnancy, tubal factor infertility, pelvic inflammatory disease, and long-term pelvic pain. In this study, it was found that a primary antibody dilution of 1:400 using methanol fixed HeLA cells, as derived from Carrasco, et al. protocol, was only optimal for PMP-C staining. Pmp-A, Pmp-B, and Pmp-F were found to stain brighter with form

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31

Himmelein, Susanne. "Aufrechterhaltung der HSV-spezifischen CD8+ T-Zellantwort im Trigeminusganglion." Diss., lmu, 2010. http://nbn-resolving.de/urn:nbn:de:bvb:19-114857.

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Thakur, Roopa. "Induction of CYR61 by oncolytic HSV infection of glioma." Connect to resource, 2007. http://hdl.handle.net/1811/25252.

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Thesis (Honors)--Ohio State University, 2007.<br>Title from first page of PDF file. Document formatted into pages: contains 57 p.; also includes graphics. Includes bibliographical references (p. 54-57). Available online via Ohio State University's Knowledge Bank.

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Sahm, Alexander [Verfasser]. "Prognose der Schnittkräfte bei der HSC-Bearbeitung / Alexander Sahm." Aachen : Shaker, 2003. http://d-nb.info/1174513950/34.

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Holman, Holly A. "Investigation of ICP34.5 and its role in HSV pathogenicity." Thesis, University of Glasgow, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321914.

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Thurlow, Johanna Katharine. "Characterisation of the HSV-1 DNA packaging protein UL17." Thesis, University of Glasgow, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.404282.

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Bonkhofer, Florian. "Identification of novel Runx1 targets involved in HSC development." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:4badf9f4-f796-4063-8176-dd57644fd811.

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Haematopoietic stem and progenitor cells (HSPCs) are de novo generated within in the ventral aspects of the embryonic dorsal aorta (DA). Cells of this haemogenic endothelium (HE) will eventually undergo an endothelial to haematopoietic transition (EHT) that involves cell budding out of the aortic wall. Despite the detailed description of the cellular events, the exact haemogenic lineage path and the underlying molecular mechanism that establish full haematopoietic competence are still not entirely understood. The transcription factor Runx1 is critical for the emergence of HSPCs and shows expre

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Pollara, Gabriele. "Functional consequences of HSV-1 infection of dendritic cells." Thesis, University College London (University of London), 2005. http://discovery.ucl.ac.uk/1446256/.

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Herpes simplex virus-1 (HSV-1) infects a significant proportion of the population, causing widespread morbidity and occasional mortality. An understanding of the interaction of this virus with the immune system will aid in the development of vaccines to reduce the prevalence of this infection, and in evaluating its potential role as a vector in immunotherapy. Dendritic cells (DC) are the critical initiators of adaptive immune responses to HSV-1 and are likely to encounter the virus early after infection of the skin or mucosa. This thesis aims to describe the functional consequences of the inte

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Ishino, Ryo. "Oncolytic virus therapy with HSV-1 for hematologic malignancies." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/263570.

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Hotakainen, L. (Lari). "HSC-3 -solujen eksosomit ja CAV-1 -proteiinin ilmeneminen." University of Oulu, 2017. http://urn.fi/URN:NBN:fi:oulu-201705312281.

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Kielisyövän tuumorimikroympäristö ja sen eri komponentit ovat olleet viime aikoina kiivaan tutkimuksen kohteena. Näillä tekijöillä näyttäisi olevan merkitystä syövän kasvussa, invaasiossa ja leviämisessä. Mikroympäristön ominaisuuksiin vaikuttaa todennäköisesti syöpäsolujen ja tuumorin mikroympäristön molekyylivälitteinen keskustelu, ja tämän vuoropuhelun viestinvälittäjiä ovat esimerkiksi eksosomit. Eksosomit ovat kehon normaalien solujen ja syöpäsolujen erittämiä lipidikaksoiskalvollisia mikrovesikkeleitä, jotka voivat spesifisesti sitoutua kohdesoluunsa, ja muokata sen toimintaa esimerkiksi

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Alamri, Badrieah Mohammad. "Effects of Myrrh on HSV-1 Using Plaque Assay." Wright State University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=wright1481628828816542.

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Thornton, Keith Edward. "Characterization of the HSV-1 polymerase accessory factor UL42 /." The Ohio State University, 1998. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487949508370729.

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Enk, Dirk. "Untersuchungen zum dynamischen Stabilitätsverhalten von Fräswerkzeugen zur HSC-Bearbeitung." Essen Vulkan-Verl, 2009. http://d-nb.info/995794677/04.

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Bertram, Kirstie Melissa. "Presentation of HSV antigens and lipopeptides to T cells." Thesis, The University of Sydney, 2014. http://hdl.handle.net/2123/14090.

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Currently there is no effective vaccine for genital and neonatal herpes. The most efficacious vaccine candidates in clinical trials to date failed to induce protective CD8+ T cell immunity and yet CD4+ and CD8+ T cells play a major role in controlling HSV mucocutaneous infection in humans. This thesis aimed at defining immunodominant CD8+ T cell epitopes from Herpes simplex virus type 2 (HSV2) and to combine these with T helper cell epitopes and the TLR2 agonist, Pam2Cys, as self-adjuvanted lipopeptides for use as possible HSV vaccine candidates. An ICP8 peptide ‘9’ was identified by predicti

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Sakamaki, Taro. "Hoxb5 defines the heterogeneity of self-renewal capacity in the hematopoietic stem cell compartment." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/263564.

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CINTRA, Diogo Tenório. "Metodologia de paralelização híbrida do DEM com controle de balanço de carga baseado em curva de Hilbert." Universidade Federal de Pernambuco, 2016. https://repositorio.ufpe.br/handle/123456789/17554.

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Submitted by Fabio Sobreira Campos da Costa (fabio.sobreira@ufpe.br) on 2016-07-28T12:46:53Z No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) tese_diogotc_final.pdf: 7303783 bytes, checksum: f9959e8bb63b91d247de9903c2484d35 (MD5)<br>Made available in DSpace on 2016-07-28T12:46:53Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) tese_diogotc_final.pdf: 7303783 bytes, checksum: f9959e8bb63b91d247de9903c2484d35 (MD5) Previous issue date: 2016-01-29<br>Esta tese apresenta uma metodologia de parale

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Huot, Nicolas. "Relation entre l’expression des LAT et du gène RL2 pendant la latence du virus HSV-1." Thesis, Paris 11, 2012. http://www.theses.fr/2012PA114860/document.

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Le virus de l’herpès simplex de type 1 (HSV1) établit une infection latente dans le système nerveux de l'homme, au cours de laquelle un type de transcrits, appelés LATs (pour latency associated transcripts), s'accumule dans les neurones infectés. Le rôle clef des LATs dans le contrôle de la latence virale est reconnu. Cependant, depuis leur découverte dans les années 80, leur mécanisme d'action reste non élucidé.Le gène des LATs est transcrit en un LAT primaire de 8,3kb, qui est épissé, conduisant à la formation de deux LATs stables : le LAT2kb et le LAT1.5kb. De façon remarquable, le LAT2kb e

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Ghiaur, Gabriel. "The role of Rho GTPases in hematopoietic stem cell biology RhoA GTPase regulates adult HSC engraftment and Rac1 GTPases is important for embryonic HSC /." Cincinnati, Ohio : University of Cincinnati, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1204374567.

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Rozenberg, Flore. "Analyse de determinants de virulence du virus herpes simplex (hsv) dans l'encephalite herpetique humaine ; contribution a l'etude du pouvoir neuropathogene de hsv chez l'homme." Paris 11, 1997. http://www.theses.fr/1997PA114857.

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Russell, Luke Russell. "Oncolytic Virus Expression of PTENα Directs Antitumor Immune Response". The Ohio State University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=osu1511979972361293.

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Zayas, Jennifer. "Regulation of HSC Self-Renewal and Differentiation by Pumilio Proteins." Scholarly Repository, 2008. http://scholarlyrepository.miami.edu/oa_dissertations/300.

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Evolutionarily conserved Pumilio (Pum) RNA-binding proteins act as translational repressors during embryo development and cell fate specification. Previous work in the lab has shown that over-expression of Pum2 (Pum2-EML) supports maintenance and suppresses mutilineage differentiation of murine multipotent HSC/MPP-like cell line EML. The subsequent analysis of HSC markers and functional analysis has revealed that wt EML cells share the LKS CD34 positive phenotype, whereas the majority Pum2-EML cells are similar to LKS CD34 negative. The CD34 positive wt EML cells can be divided into CD34low, C

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