Academic literature on the topic 'HT 5055'

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Journal articles on the topic "HT 5055"

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Littlejohn, G., T. Smith, K. Tymms, et al. "THU0209 UPTAKE OF JANUS KINASE INHIBITORS FOR MANAGEMENT OF RHEUMATOID ARTHRITIS IN AUSTRALIA." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 329.2–329. http://dx.doi.org/10.1136/annrheumdis-2020-eular.5055.

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Background:JAK inhibitors (JAKi) are oral tsDMARDs with a different mode of action (MOA) to both oral cs- and parenteral bDMARDs. In Australia the cost of b/tsDMARDs for treatment of RA is subsidized if the patient has documented high levels of clinical/laboratory disease activity and has not responded to a pre-specified combination of csDMARDs, including MTX. Once eligible for subsidy the clinician can prescribe the b/tsDMARD deemed most clinically appropriate.Objectives:To determine the patterns of use and reasons for initiation and discontinuation of JAKi in real-world rheumatology practice
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Chen, P. R., E. C. Leffeler, L. D. Spate, and R. S. Prather. "71 Removal of hypotaurine from porcine embryo culture medium decreases message for pro-apoptotic genes but does not affect development at low oxygen tension." Reproduction, Fertility and Development 31, no. 1 (2019): 161. http://dx.doi.org/10.1071/rdv31n1ab71.

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Hypotaurine (HT) is a routine additive to embryo culture medium, acting primarily as an oxygen radical scavenger. However, the practice of culturing embryos at ~5% O2 has been widely adopted because this is more physiologically relevant to the oxygen tensions detected in the oviduct and uterus. Thus, the utility of HT may be diminished as fewer oxygen radicals are produced during culture at 5% O2. The objective here was to determine the effects of removing HT from our porcine embryo culture medium (MU2) on the development of embryos incubated at a lower oxygen tension (5% O2) compared with atm
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Lee, Hae-Young, Ju-Yeon Lee, Ho-Gyun Shin, et al. "The Korean Hypertension Cohort study: design and baseline characteristics." Korean Journal of Internal Medicine 36, no. 5 (2021): 1115–25. http://dx.doi.org/10.3904/kjim.2020.551.

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Background/Aims: Hypertension (HT) has a significant impact on public health and medical expenses. However, HT is a chronic disease that requires the long-term follow-up of a large number of patients.Methods: The Korean Hypertension Cohort (KHC) study aimed to develop a model for calculating cardiovascular risk in HT patients by linking and utilizing the detailed clinical and longitudinal data from hospitals and the national health insurance claim database, respectively. This cohort had a planned sample size of over 11,000 HT patients and 100,000 non-HT controls. Eligible patients were hyperte
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Ruggeri, E. M., E. Bria, P. Carlini, et al. "Does progression-free-survival (PFS) correlate with overall- and cancer-specific survival (OS/CSS) in randomized clinical trials (RCTs) exploring the addition of hormonal therapy (HT) to radiotherapy (RT) for early prostate cancer (EPC)? Analysis of six RCTs." Journal of Clinical Oncology 25, no. 18_suppl (2007): 5056. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.5056.

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5056 Background: Although PFS is considered the standard primary end-point in EPC, the correlation with OS has never been explored in RCTs randomizing patients (pts) to HT plus radiotherapy (RT) versus RT. Given the relatively long prognosis in this disease setting, the correlation between PFS and CSS should be investigated as well. Methods: All phase III trials reporting all outcome’ data were considered eligible. The correlation has been explored according to a linear regression model considering both each single outcome pair (PFS, OS and CSS rates) for all arms, and each reported Hazard Rat
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Ozdemir, Yurday, Ibrahim Acibuci, Ugur Selek, and Erkan Topkan. "Preliminary Simulation Study of Carotid Artery and Pharyngeal Constrictor Muscle Sparing-Radiotherapy in Glottic Carcinoma." Technology in Cancer Research & Treatment 19 (January 1, 2020): 153303382095698. http://dx.doi.org/10.1177/1533033820956989.

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Background: This preliminary simulation study aimed to compare the dosimetric outcomes of carotid arteries (CAs) and pharyngeal constrictor muscle (PCM) in patients with T1N0M0 glottic carcinoma undergoing helical tomotherapy-intensity modulated radiotherapy (HT-IMRT) and 3-dimensional conformal radiotherapy (3D-CRT) plans. Methods: In addition to the clinical target volume (CTV) which was defined as the entire larynx, the CAs and PCM of 11 glottic carcinoma patients were delineated. The CTV was uniformly expanded 5 mm to create a planning target volume (PTV) relative to the PCM and at a dista
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Potts, Jeffrey T., Kelly P. McKeown, and Artin A. Shoukas. "Reduction in arterial compliance alters carotid baroreflex control of cardiac output in a model of hypertension." American Journal of Physiology-Heart and Circulatory Physiology 274, no. 4 (1998): H1121—H1131. http://dx.doi.org/10.1152/ajpheart.1998.274.4.h1121.

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Baroreflex regulation of cardiac output is determined by the performance of the heart as well as the available blood flow returning to the heart (i.e., venous return). We hypothesized that a decrease in arterial compliance (Ca) would affect carotid baroreflex control of cardiac output by altering the slope of the venous return curve (VR curve). Baroreflex control of systemic arterial pressure (Pa), central venous pressure (Pv), heart rate, cardiac output (CO), and peripheral vascular resistance ( R) were determined during bilateral carotid occlusion (BCO) in spontaneously hypertensive (hyperte
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Woźniak, Andrzej, and Dorota Gawęda. "TILLAGE MANAGEMENT EFFECTS ON PEA YIELD AND CHEMICAL COMPOSITION OF PEA SEEDS." Acta Scientiarum Polonorum Hortorum Cultus 18, no. 1 (2019): 151–60. http://dx.doi.org/10.24326/asphc.2019.1.15.

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Productivity of plants is determined by multiple factors that directly affect one another, therefore yield variability may be high and difficult to predict. Most often, however, a lower crop yield is achieved in the notillage system than in the ploughing system. An exact field experiment was undertaken to determine the yield and chemical composition of pea seeds sown under conditions of: 1) conventional tillage – CT (shallow ploughing and harrowing after the harvest of previous crop, pre-winter ploughing in winter); 2) reduced tillage – RT (stubble cultivator after the harvest of previous crop
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Stosor, V., M. Angarone, K. Scarsi, et al. "505: CMV Infection after Heart Transplantation (HT) Occurs in the Setting of Prolonged Valganciclovir (VGC) Prophylaxis (Proph)." Journal of Heart and Lung Transplantation 28, no. 2 (2009): S241. http://dx.doi.org/10.1016/j.healun.2008.11.512.

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Siker, M. L., X. S. Qi, B. Hu, S. J. Wong, X. A. Li, and B. Erickson. "Helical tomotherapy for anal cancer: Initial clinical outcomes and organ motion." Journal of Clinical Oncology 29, no. 4_suppl (2011): 530. http://dx.doi.org/10.1200/jco.2011.29.4_suppl.530.

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530 Background: Helical tomotherapy (HT) delivers rotational IMRT with megavoltage CT (MVCT) guidance for patient positioning, offering improved dose conformality and accuracy. We report preliminary clinical outcomes using HT in patients with anal cancer with estimated organ motion and delivered doses. Methods: From 9/2005-8/2009, 15 patients with anal cancer were treated with HT and concurrent chemotherapy (MMC 10 mg/m2 IV bolus d1 and 29; 5FU 1,000 mg/m2/day CI d1-4 and 29-32). Median doses for primary tumor, involved lymph nodes and uninvolved lymph nodes were 50.5, 50.4 and 45 Gy. Dose spe
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Aizer, Ayal A., John Phillips, Ming-Hui Chen, Danjie Zhang, Marian Loffredo, and Anthony Victor D'Amico. "Detecting lower in addition to the highest Gleason score prostate cancer on core biopsy and the risk of prostate cancer-specific mortality." Journal of Clinical Oncology 31, no. 15_suppl (2013): 5051. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.5051.

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5051 Background: We evaluated the risk of prostate cancer-specific mortality (PCSM) following definitive treatment in men with at least one prostate biopsy core with a Gleason score (GS) lower than the highest GS identified. This pattern termed “ComboGS” in a concurrent submission was shown to be associated with a significant reduction in the odds of upgrading at radical prostatectomy (RP). Methods: In this validation cohort 666 men with localized or locally advanced prostate cancer, men were diagnosed via a transrectal, ultrasound-guided needle prostate biopsy (median 6, IQR 5-6 cores) and tr
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Dissertations / Theses on the topic "HT 5055"

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Boss, Aleksandra. "Of Opaque Bodies and Transparent Eyeballs." Doctoral thesis, Humboldt-Universität zu Berlin, 2018. http://dx.doi.org/10.18452/19153.

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Die vorliegende Dissertation stellt eine Interpretation von Thomas Paines THE AGE OF REASON (1794) und Ralph Waldo Emersons NATURE (1836) als politiktheoretische Traktate vor, die normative Demokratiekonstrukte entwickeln. Diese Demokratiekonstrukte werden anhand ihrer Parameter vergleichend und historisierend gelesen. Die Annahme ist hierbei, dass sich die normativen Demokratieentwürfe beider Autoren mithilfe der Denkfigur des rhizomatischen Panoptizismus explizieren lassen. Die Dissertation leitet diese Denkfigur anhand von Texten des französischen Poststrukturalismus und auf Grundlage des s
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Seibel, Jan. "Einflüsse von 17β-Östradiol, ER-subtypspezifischen Agonisten und Phytoöstrogenen auf inflammatorische Prozesse im Kolon". Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2007. http://nbn-resolving.de/urn:nbn:de:swb:14-1188153275702-60805.

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Die niedrige Inzidenz chronisch-entzündlicher Darmerkrankungen (CED) in ostasiatischen Ländern im Vergleich zu Westeuropa und den USA könnte auf unterschiedliche Lebensstile und Ernährungsgewohnheiten zurückzuführen sein. Asiaten nehmen mit der Nahrung viel höhere Mengen an Isoflavonen zu sich als Europäer und US-Amerikaner. Diese sind in der Lage, wie natürliche Östrogene an Östrogenrezeptoren (ER) zu binden. Für das Östrogen 17β-Östradiol (E2) sowie selektive Liganden des ERβ sind antiinflammatorische Wirkungen im Darm bereits nachgewiesen worden. Diese Arbeit untersuchte in Modellsystemen f
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