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Journal articles on the topic 'Hu 4796'

Author: Grafiati

Published: 27 July 2024

Last updated: 31 July 2025

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1

Yang, Lian-Fang, Ben-Jin Hu, and John C. Morse. "Interesting new Chinese species of Leptoceridae and Odontoceridae (Insecta Trichoptera) from several recent collecting efforts." Zootaxa 4766, no. 4 (2020): 593. https://doi.org/10.11646/zootaxa.4766.4.6.

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Yang, Lian-Fang, Hu, Ben-Jin, Morse, John C. (2020): Interesting new Chinese species of Leptoceridae and Odontoceridae (Insecta Trichoptera) from several recent collecting efforts. Zootaxa 4766 (4): 593-593, DOI: 10.11646/zootaxa.4766.4.6

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2

Alshoabi, Sultan Abdulwadoud, Reyan Mohammed Alharbi, Rufaydah Bader Algohani, et al. "Grading of Fatty Liver Based on Computed Tomography Hounsfield Unit Values versus Ultrasonography Grading." Gastroenterology Insights 15, no. 3 (2024): 588–98. http://dx.doi.org/10.3390/gastroent15030043.

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Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) ranges from hepatic steatosis to nonalcoholic steatohepatitis and may lead to liver cirrhosis. This study aimed to assess the feasibility of numerical grading MASLD using noncontrast computed tomography (NCCT). Methods: In a retrospective study of 166 patients diagnosed with MASLD between June 2020 and January 2024, MASLD was graded by ultrasonography, and liver density was measured on NCCT. The MASLD grades and NCCT densities were compared. Results: The MASLD grades were distributed as follows: grade 0 (n = 79, 47.6%

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Hamouda, Abdelrahman M., Zach Pennington, Rahul Kumar, et al. "Impact of Frailty and Other Factors as Estimated by HU to Predict Response to Anabolic Bone Medications." Journal of Clinical Medicine 14, no. 9 (2025): 3247. https://doi.org/10.3390/jcm14093247.

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Introduction: Bone health optimization is a key component of the preoperative management of spine surgery patients, as poor bone quality increases the odds of mechanical complications. The present study aimed to achieve the following: (1) compare the relative efficacy of current osteoporosis medications in improving bone quality; (2) identify factors influencing treatment response in preoperative spine surgery patients. Methods: Patients treated at a single, multisite institution who received osteoporosis treatment were identified. Data were gathered on pre- and post-treatment lumbar spine Hou

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Linh, Đỗ Đức, Đoàn Thị Giang, Đinh Trung Thành та Phạm Hồng Đức. "Đánh giá mối tương quan giữa lắng đọng mỡ tuyến tụy trên cắt lớp vi tính với chỉ số khối cơ thể và đái tháo đường tuýp 2". Tạp chí Nghiên cứu Y học 180, № 7 (2024): 213–22. http://dx.doi.org/10.52852/tcncyh.v180i7.2553.

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Nghiên cứu nhằm mục đích xác định các mức độ lắng đọng mỡ trong tụy (IPFD) trên cắt lớp vi tính ở người bình thường và đánh giá mối tương quan với các chỉ số khối cơ thể (BMI) và đái tháo đường tuýp 2. Các chỉ số này nhằm xác định IPFD qua quan sát (chia làm 4 độ 0, 1, 2, 3) và đo tỷ trọng xác định trên cắt lớp vi tính. Tổng có 208 người độ tuổi 47,6 ± 14,8 được chụp cắt lớp vi tính ổ bụng và xác định là không có bệnh lý viêm hoặc u tụy. Kết quả cho thấy: độ 0, 1, 2 chiếm tỷ lệ ở vùng đầu tụy và đuôi tụy lần lượt là: 86,5%, 12% và 1,4%; và 86,1%, 13%, và 1,0%, không có trường hợp nào lắng đọng

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5

Alvarez, Ofelia A., Sandra Echenique, Hector Rodriguez-Cortes, et al. "Patient Perception on Health Care Delivery for Sickle Cell Disease and Opportunities for Quality Improvement." Blood 134, Supplement_1 (2019): 5862. http://dx.doi.org/10.1182/blood-2019-123215.

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The Health Resources and Services (HRSA)-sponsored Sickle Cell Disease (SCD)Treatment Demonstration Regional Collaborative Program, EMBRACE SCD Florida has three aims: 1. To educate providers about SCD, 2. To assess patients' perception on health care and barriers encountered, and 3. To increase hydroxyurea (HU) treatment as disease-modifying therapy. We report the patients' perception on health care delivery as assessed by surveys of 65 patients at two SCD centers in South Florida. All participants signed the IRB-approved informed consent/assent and completed a 46-question survey. Surveys add

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Ballout, Farah, Heng Lu, Zheng Chen, et al. "Abstract 4776: NRF2 is overexpressed in esophageal adenocarcinoma and its targeting sensitizes tumor cells to cisplatin through induction of ferroptosis and apoptosis." Cancer Research 83, no. 7_Supplement (2023): 4776. http://dx.doi.org/10.1158/1538-7445.am2023-4776.

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Abstract Background: Esophageal adenocarcinoma (EAC) is the predominant type of esophageal cancer in the United States, with the 5-year survival rate is below 20%. EAC develops through Barrett’s esophagus (BE)-dysplasia-carcinoma cascade. Gastroesophageal reflux disease (GERD), where acidic bile salts refluxate into the esophagus, is the main risk factor for the development of BE and its progression to EAC. The NFE2-related factor 2 (NRF2) is the master cellular antioxidant regulator, involving in many cancer hallmarks. Methods and Results: Using western blotting and immunohistochemistry techn

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Zhu, Kuichun, Elvira Gerbino, Darrin M. Beaupre, et al. "Farnesyltransferase inhibitor R115777 (Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhibit tumor growth of multiple myeloma cells." Blood 105, no. 12 (2005): 4759–66. http://dx.doi.org/10.1182/blood-2004-11-4307.

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Abstract Despite major advances, multiple myeloma (MM) remains an incurable malignancy. Recently we have found that disease stabilization was achieved in 64% of patients with advanced MM treated with the farnesyltransferase inhibitor R115777 (Zarnestra) in a phase 2 clinical trial. In order to enhance R115777 antitumor activity in MM, we examined the combination of this novel agent with other anticancer drugs in MM cell lines. In this study, R115777 was found to synergize with paclitaxel and docetaxel, but not with other chemotherapy agents, including doxorubicin, 5-fluorouracil, cisplastin, m

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Alhejazi, Ayman, Mahmoud Aljurf, Entezam Sahovic, et al. "Leukemia during Pregnancy: 32 Cases from a Single Institution." Blood 104, no. 11 (2004): 3153. http://dx.doi.org/10.1182/blood.v104.11.3153.3153.

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Abstract In an attempt to evaluate the outcome of leukemia during pregnancy we performed a study of all such cases identified in our institution leukemia database. Thirty two cases were identified as cases of leukemia during pregnancy among the cohort of patients treated between January 1991 and July 2003. The cases were AML (15), ALL (6) and CML (11). At diagnosis the median age was 24.5 years and the median gestational age was 16 weeks. Twenty patients were treated for their leukemia during pregnancy at a median gestational age of 20 weeks (4 in the first trimester, 8 in the second trimester

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Fauny, M., M. Halin, E. Allado, et al. "AB1334 SCANOGRAPHIC EVALUATION OF BONE FRAGILITY 2 YEARS AFTER BARIATRIC SURGERY IN OBESE PATIENTS: AN OBSERVATIONAL STUDY." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1773.2–1773. http://dx.doi.org/10.1136/annrheumdis-2022-eular.871.

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BackgroundOsteoporosis is a common disease whose prognosis can be seriously impacted by the development of fractures that lead to functional limitations and may even have life-threatening sequelae (1). CT is useful for diagnosing vertebral fracture (VF) and measuring the scanographic bone attenuation coefficient of the first lumbar vertebra (SBAC- L1). Obesity might be a protective factor against bone loss and osteoporosis (2). Nonetheless, epidemiological studies have reported an association between obesity and an increased risk of fragility fractures (3) and suggested that obesity may be a r

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Jain, Akshat, Lisa Roberts, and Safiye Sahin. "Global Sickle Cell Quality of Life: Oral Pain Medication Frequency, Health Outcomes, and Emotional Well-Being." Blood 144, Supplement 1 (2024): 5060. https://doi.org/10.1182/blood-2024-206337.

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Background: Sickle cell disease (SCD) profoundly affects physical health, emotional well-being, and overall quality of life(QOL). Oral pain medication (OPM) use is essential to manage vaso occlusion in SCD and is a key utilization metric for disease severity and management effectiveness. Understanding how this frequency relates with health status, treatment practices, and psychosocial factors may explain unmet needs in these regions and help direct public policy. We investigated the relationships between frequency of OPM usage and key physical, psychosocial health metrics, and satisfaction wit

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Chen, Chen, Charles Huang, Min Xu, et al. "Abstract 476: ABM-1310 has significant improved BBB-penetration and intracranial tumor growth inhibition compared to FDA approved BRAF inhibitors." Cancer Research 83, no. 7_Supplement (2023): 476. http://dx.doi.org/10.1158/1538-7445.am2023-476.

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Abstract ABM-1310 is a novel small-molecule BRAF inhibitor designed to treat primary CNS tumors or advanced cancer patients with BRAFv600 mutation, with or without brain metastasis. Currently, a Phase I clinical trial of ABM-1310 is actively recruiting patients at multiple clinical centers in US.BRAF mutation takes place in about 8% of all tumors, among which around 90% is V600E amino acid mutation. BRAFv600 mutation causes BRAF’s continuous activation, and results in cancerous cells eventually. Melanoma is the most common cancer type with BRAFv600 mutation, and ~50% of melanoma will develop b

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12

Chandran M, Obhuli, Saikiran Pendem, Priya P S, Cijo Chacko, Priyanka ,, and Rajagopal Kadavigere. "Comparison of image quality between Deep learning image reconstruction and Iterative reconstruction technique for CT Brain- a pilot study." F1000Research 13 (June 26, 2024): 691. http://dx.doi.org/10.12688/f1000research.150773.1.

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Background Non-contrast Computed Tomography (NCCT) plays a pivotal role in assessing central nervous system disorders and is a crucial diagnostic method. Iterative reconstruction (IR) methods have enhanced image quality (IQ) but may result in a blotchy appearance and decreased resolution for subtle contrasts. The deep-learning image reconstruction (DLIR) algorithm, which integrates a convolutional neural network (CNN) into the reconstruction process, generates high-quality images with minimal noise. Hence, the objective of this study was to assess the IQ of the Precise Image (DLIR) and the IR

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Hu, Yongxian, Yanjun Gu, Lixia Sheng та ін. "Decitabine Facilitates the Generation of Functional Regulatory γδT Cells Via Foxp3 Gene Demethylation and NF-κB up-Regulation". Blood 120, № 21 (2012): 3281. http://dx.doi.org/10.1182/blood.v120.21.3281.3281.

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Abstract Abstract 3281 Regulatory γδT cells (γδTregs) are capable of suppressing T-cell activation and proliferation (Rita et al Journal of immunology 2009). Our previous studies demonstrated the immunosuppressive features of γδTregs and further supported the use of γδTregs as a promising therapeutic strategy for the adoptive immunotherapy of allograft rejection, post-transplantation graft-versus-host disease (GVHD) and autoimmune diseases (Hu et al ASH abstract 2011). To this end, large-scale, efficient expansion of γδTregs represents a fundamentally important prerequisite for their clinical

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Maia, Andreia, Mubin Tarannum, Sara Piccinelli та ін. "Abstract 870: Engineering of a novel Buddy-CAR system: CAR-NK cells expressing IL7/IL7Rα exhibit superior proliferation and anti-tumor responses while promoting trans-activation of the bystander T cells". Cancer Research 85, № 8_Supplement_1 (2025): 870. https://doi.org/10.1158/1538-7445.am2025-870.

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Abstract Natural killer (NK) and chimeric antigen receptor (CAR) NK cells offer a promising platform for cellular immunotherapy. However, the immunosuppressive tumor microenvironment (TME), particularly in pancreatic cancer, negatively affects the efficacy of cell therapies. IL7 is an attractive cytokine to module TME as it promotes CD4+ and CD8+ T cell proliferation while maintaining them in a less differentiated state, improving metabolic profile, and preventing exhaustion. Mature NK cells are minimally responsive to IL7 as they lack the expression of IL7Rα. To overcome this, we engineered t

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15

Xu, Rui-Hua, Dan-Yun Ruan, Rong-Bo Lin, et al. "Abstract CT010: Phase I dose-escalation and expansion study of JS107, a claudin 18.2 (CLDN18.2)-targeting antibody-drug conjugate (ADC), as monotherapy or in combination for patients (pts) with advanced solid tumors." Cancer Research 85, no. 8_Supplement_2 (2025): CT010. https://doi.org/10.1158/1538-7445.am2025-ct010.

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Abstract Background: JS107 is a monomethyl auristatin E conjugated, CLDN18.2 specific ADC. JS107 exhibited potent anti-tumor activities in preclinical studies with a tolerable safety profile. Here we report the safety and efficacy results of JS107 monotherapy or in combination for pts with advanced solid tumors from the first-in-human phase 1 trial (NCT05502393). Methods: In Part A of the study, pts with advanced solid tumors refractory to standard therapies were treated with JS107 at 0.15-3.5 mg/kg Q3W during dose escalation and CLDN18.2+ pts were treated with JS107 at 2.0 and 3.0 mg/kg Q3W d

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16

Xu, Binghe, Fei Ma, Min Yan, et al. "Abstract GS1-03: Pyrotinib or placebo in combination with trastuzumab and docetaxel for untreated HER2-positive metastatic breast cancer (mBC): prespecified final analysis of progression-free survival (PFS) of the phase 3 PHILA trial." Clinical Cancer Research 31, no. 12_Supplement (2025): GS1–03—GS1–03. https://doi.org/10.1158/1557-3265.sabcs24-gs1-03.

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Abstract Background: The interim analysis of the PHILA trial (NCT03863223) revealed that pyrotinib (an irreversible tyrosine kinase inhibitor targeting EGFR, HER2, and HER4) in combination with trastuzumab and docetaxel (PyroHT) significantly improved PFS compared to placebo in combination with trastuzumab and docetaxel (HT) in untreated HER2-positive mBC patients (Ma et al., BMJ, 2023). However, the overall survival (OS) data was immature at that time. Here, we present the prespecified final analysis of PFS, as well as long-term efficacy and safety outcomes from the PHILA trial following an a

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17

Ricigliano, Vito, and Barbara Fossati. "Paraneoplastic Parkinsonism-Dysautonomia Due To Anti-Hu Antibodies (4794)." Neurology 94, no. 15_supplement (2020). http://dx.doi.org/10.1212/wnl.94.15_supplement.4794.

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18

"RETRACTION: PAK5 Facilitates the Proliferation, Invasion and Migration in Colorectal Cancer Cells." Cancer Medicine 13, no. 24 (2024). https://doi.org/10.1002/cam4.70520.

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ABSTRACTRETRACTION: S. Huang, Y. Zhu, C. Wang, X. Li, X. Cui, S. Tu, Lijuan You, J. Fu, Z. Chen, W. Hu and W. Gong, “PAK5 Facilitates the Proliferation, Invasion and Migration in Colorectal Cancer Cells,” Cancer Medicine 9, no. 13 (2020): 4777–4790, https://doi.org/10.1002/cam4.3084.The above article, published online on 08 May 2020 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the authors; the journal Editor‐in‐Chief, Stephen Tait; and John Wiley & Sons Ltd. The retraction has been agreed due to an overlap between the Flag‐wtPAK5 and Flag‐wtPAK5

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19

Kim, Keong-Hwan, Jun Hee Lee, and Eic Ju Lim. "Weak psoas and spine extensors potentially predispose to hip fracture." HIP International, January 30, 2020, 112070002090433. http://dx.doi.org/10.1177/1120700020904337.

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Introduction: We performed a computed tomography analysis of muscle composition characteristics in hip fracture patients and non-hip fracture controls. Methods: In total, 43 patients (9 men, 34 women) were included in the hip fracture group, matched 1 to 1 with non-hip fracture controls. Muscle cross-sectional areas were measured in axial CT scan at the body level of the 4th lumbar vertebra (L4), intervertebral disc level between the 5th lumbar vertebra and the 1st sacral vertebra (L5-S1) and just below level of the lesser trochanter (LT). Attenuation was also evaluated through the mean Hounsf

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Khorasanizadeh, MirHojjat, Yu-Ming Chang, Alejandro Enriquez-Marulanda, et al. "Morphological changes in chronic subdural hematomas following upfront middle meningeal artery embolization: sequence, timing, and association with outcomes." Journal of Neurosurgery, November 2021, 1–14. http://dx.doi.org/10.3171/2021.8.jns211691.

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OBJECTIVE Middle meningeal artery embolization (MMAE) is an increasingly utilized approach for the treatment of chronic subdural hematomas (CSDHs). The course of morphological progression of CSDHs following MMAE is poorly understood. Herein, the authors aimed to describe these morphological changes and assess their prognostic significance for the outcomes on follow-up. METHODS A single-institution retrospective cohort study of CSDH cases treated by upfront MMAE, without prior or adjunctive surgical evacuation, was performed. Clinical outcomes, complications, and the need for rescue surgery on

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sprotocols. "Non-invasive measurement of real-time oxygen flux in plant systems with a self-referencing optrode." January 20, 2015. https://doi.org/10.5281/zenodo.14081.

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Authors: Yinglang Wan, Eric McLamore, Lusheng Fan, Huaiqing Hao, D. Marshall Porterfield, Zengkai Zhang, Wenjun Wang, Yue (Jeff) Xu & Jinxing Lin ### Abstract This protocol describes an integration of the Non-invasive Micro-test Technique and Oxygen Optrode (NMT-OO) to quantify rhizosphere oxygen fluxes in Arabidopsis. The optrode has high sensitivity and selectivity in the measurement of oxygen concentrations and fluxes at the cellular level. In particular, application of the NMT-OO using the self-referencing method avoids environmental electromagnetic noise and hysteresis/calibration dri

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Dolomatov, S.I., та W. Zukow. "Эпигенетика почек = Kidneys epigenetics". 7 липня 2019. https://doi.org/10.5281/zenodo.3270754.

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<strong>Dolomatov S.I., Zukow W. </strong><strong>Эпигенетика почек</strong><strong> = Kidney</strong><strong>s</strong><strong> epigenetics</strong><strong>. </strong><strong>RSW. Radom,</strong><strong> 144 </strong><strong>p. ISBN </strong><strong>9780359774524</strong><strong>.</strong><strong> DOI </strong><strong>http://dx.doi.org/10.5281/zenodo.3270699</strong><strong> PBN Poland </strong><strong>https://pbn.nauka.gov.pl/sedno-webapp/works/917606</strong>           <strong>Radomska Szkoła Wyższa w Radomiu, Radom, Poland</strong>         &nbsp

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