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Journal articles on the topic 'HU Jie'

Author: Grafiati

Published: 25 May 2024

Last updated: 31 July 2025

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1

Stover Gingerich, Barbara. "Introducing Special Issue Editor Jie Hu, PhD, RN." Home Health Care Management & Practice 22, no. 7 (2010): 543. http://dx.doi.org/10.1177/1084822310375498.

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2

Yang, Guang-Yu, Jia-Meng Dai, Qi-Li Mi, et al. "Cyclopiazonic acid type indole alkaloids from Nicotiana tabacum-derived fungus Aspergillus versicolor and their anti-tobacco mosaic virus activities." Phytochemistry 198 (June 30, 2022): 1–7. https://doi.org/10.1016/j.phytochem.2022.113137.

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Yang, Guang-Yu, Dai, Jia-Meng, Mi, Qi-Li, Li, Zhen-Jie, Li, Xue-Mei, Zhang, Jian-Duo, Wang, Jin, Li, Yin-Ke, Wang, Wei-Guang, Zhou, Min, Hu, Qiu-Fen (2022): Cyclopiazonic acid type indole alkaloids from Nicotiana tabacum-derived fungus Aspergillus versicolor and their anti-tobacco mosaic virus activities. Phytochemistry (113137) 198: 1-7, DOI: 10.1016/j.phytochem.2022.113137, URL: http://dx.doi.org/10.1016/j.phytochem.2022.113137

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3

Chen, Zhi-Qiang, Hua-Li Hu, Jun-Jie Zhong, Hai-Ping Shangguan, and Guo-Hua Ding. "Advertisement calls of the lesser spiny frog Quasipaa exilispinosa (Liu and Hu 1975) (Anura: Dicroglossidae)." Zootaxa 4926, no. 3 (2021): 446–50. https://doi.org/10.11646/zootaxa.4926.3.9.

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Chen, Zhi-Qiang, Hu, Hua-Li, Zhong, Jun-Jie, Shangguan, Hai-Ping, Ding, Guo-Hua (2021): Advertisement calls of the lesser spiny frog Quasipaa exilispinosa (Liu and Hu 1975) (Anura: Dicroglossidae). Zootaxa 4926 (3): 446-450, DOI: 10.11646/zootaxa.4926.3.9

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4

Dai, Jia-Meng, Qi-Li Mi, Xue-Mei Li, et al. "The anti-TMV potency of the tobacco-derived fungus Aspergillus versicolor and its active alkaloids, as anti-TMV activity inhibitors." Phytochemistry 205 (January 31, 2023): 1–9. https://doi.org/10.1016/j.phytochem.2022.113485.

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Dai, Jia-Meng, Mi, Qi-Li, Li, Xue-Mei, Gang, Du, Yang, Guang-Yu, Zhang, Jian-Duo, Wang, Jin, Li, Yin-Ke, Yang, Hai-Ying, Miao, Dong, Li, Zhen-Jie, Hu, Qiu-Fen (2023): The anti-TMV potency of the tobacco-derived fungus Aspergillus versicolor and its active alkaloids, as anti-TMV activity inhibitors. Phytochemistry (113485) 205: 1-9, DOI: 10.1016/j.phytochem.2022.113485, URL: http://dx.doi.org/10.1016/j.phytochem.2022.113485

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5

Xia, Yulu, Jing-hao Huang, Fan Jiang, et al. "The effectiveness of fruit bagging and culling for risk mitigation of fruit flies affecting citrus in China: a preliminary report." Florida Entomologist 102, no. 1 (2019): 79–84. https://doi.org/10.1653/024.102.0112.

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Xia, Yulu, Huang, Jing-hao, Jiang, Fan, He, Jia-yao, Pan, Xu-bin, Lin, Xiong-jie, Hu, Han-qing, Fan, Guo-cheng, Zhu, Shui-fang, Hou, Bo-hua, Ouyang, Ge-cheng (2019): The effectiveness of fruit bagging and culling for risk mitigation of fruit flies affecting citrus in China: a preliminary report. Florida Entomologist 102 (1): 79-84, DOI: 10.1653/024.102.0112, URL: https://www.mendeley.com/catalogue/3e17ecfa-3d90-3685-b8e0-df0d494bb9bf/

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6

Hu, Jie, Tian Zhao, Wei Geng, et al. "Correction: Synthesis of hydrophobic and hydrophilic TiO2 nanofluids for transformable surface wettability and photoactive coating." Chemical Communications 55, no. 77 (2019): 11642. http://dx.doi.org/10.1039/c9cc90390a.

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Correction for ‘Synthesis of hydrophobic and hydrophilic TiO<sub>2</sub> nanofluids for transformable surface wettability and photoactive coating’ by Jie Hu et al., Chem. Commun., 2019, 55, 9275–9278.

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7

Hu, Jie, Tao Chen, Moye Wang, Hue Sun Chan, and Zhuqing Zhang. "Correction: A critical comparison of coarse-grained structure-based approaches and atomic models of protein folding." Physical Chemistry Chemical Physics 19, no. 27 (2017): 18102. http://dx.doi.org/10.1039/c7cp90146a.

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8

Hu, Changhao, and Jie Liu. "A new troglobitic genus of the family Theridiidae Sundevall, 1833 (Araneae: Theridiidae) from China." Zootaxa 5627, no. 2 (2025): 387–400. https://doi.org/10.11646/zootaxa.5627.2.9.

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Hu, Changhao, Liu, Jie (2025): A new troglobitic genus of the family Theridiidae Sundevall, 1833 (Araneae: Theridiidae) from China. Zootaxa 5627 (2): 387-400, DOI: 10.11646/zootaxa.5627.2.9, URL: https://doi.org/10.11646/zootaxa.5627.2.9

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9

Jin, Shui-Hu, Yi-Fei Lu, Wei-Jie Chen, and Xiao-Feng Jin. "Notes on Carex (Cyperaceae) from China (VII): new synonyms and imperfectly known species." Phytotaxa 531, no. 1 (2022): 54–62. https://doi.org/10.11646/phytotaxa.531.1.4.

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Jin, Shui-Hu, Lu, Yi-Fei, Chen, Wei-Jie, Jin, Xiao-Feng (2022): Notes on Carex (Cyperaceae) from China (VII): new synonyms and imperfectly known species. Phytotaxa 531 (1): 54-62, DOI: 10.11646/phytotaxa.531.1.4

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10

Hu, Guo-Xiong, En-De Liu, Ting Zhang, Jie Cai, and Chun-Lei Xiang. "Salvia luteistriata (Lamiaceae), a new species from northeastern Sichuan, China." Phytotaxa 314, no. 1 (2017): 123–28. https://doi.org/10.11646/phytotaxa.314.1.12.

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Hu, Guo-Xiong, Liu, En-De, Zhang, Ting, Cai, Jie, Xiang, Chun-Lei (2017): Salvia luteistriata (Lamiaceae), a new species from northeastern Sichuan, China. Phytotaxa 314 (1): 123-128, DOI: 10.11646/phytotaxa.314.1.12, URL: http://dx.doi.org/10.11646/phytotaxa.314.1.12

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11

Tian, Jing, Yan Wang, Jing Ren, et al. "Rediscovery and supplemental description of Begonia hymenophylloides (Begoniaceae) as new record in China." Phytotaxa 528, no. 2 (2021): 139–43. https://doi.org/10.11646/phytotaxa.528.2.7.

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Tian, Jing, Wang, Yan, Ren, Jing, Peng, Shuai, Wang, Jun-Jie, Zhang, Cai-Fei, Hu, Guang-Wan (2021): Rediscovery and supplemental description of Begonia hymenophylloides (Begoniaceae) as new record in China. Phytotaxa 528 (2): 139-143, DOI: 10.11646/phytotaxa.528.2.7

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12

Hu, Ya-Jie, Qian Lan, Bao-Jun Su, Zhen-Feng Chen, and Dong Liang. "Structurally diverse abietane-type Diterpenoids from the aerial parts of Gaultheria leucocarpa var. yunnanensis." Phytochemistry 201 (September 30, 2022): 1–8. https://doi.org/10.1016/j.phytochem.2022.113255.

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Hu, Ya-Jie, Lan, Qian, Su, Bao-Jun, Chen, Zhen-Feng, Liang, Dong (2022): Structurally diverse abietane-type Diterpenoids from the aerial parts of Gaultheria leucocarpa var. yunnanensis. Phytochemistry (113255) 201: 1-8, DOI: 10.1016/j.phytochem.2022.113255, URL: http://dx.doi.org/10.1016/j.phytochem.2022.113255

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13

Zhong, Lin-Hong, Xiao-Zhou Hu, Yi-Tao Lin, et al. "A new species and new record of Polycystididae (Rhabdocoela: Kalyptorhynchia) from China." Zootaxa 4446, no. 1 (2018): 39–50. https://doi.org/10.11646/zootaxa.4446.1.3.

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Zhong, Lin-Hong, Hu, Xiao-Zhou, Lin, Yi-Tao, Feng, Wei-Tao, Zhuang, Jie-Yi, Zhang, Yu, Wang, An-Tai (2018): A new species and new record of Polycystididae (Rhabdocoela: Kalyptorhynchia) from China. Zootaxa 4446 (1): 39-50, DOI: 10.11646/zootaxa.4446.1.3

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14

Xiao, Qun-Ying, Hao-Yu Hu, Fen Tong, Min-Jie Li, and Xing-Jin He. "Semenovia torilifolia is conspecific with S. malcolmii (Apiaceae) based on morphology and molecular data." Phytotaxa 321, no. 3 (2017): 225–37. https://doi.org/10.11646/phytotaxa.321.3.1.

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Xiao, Qun-Ying, Hu, Hao-Yu, Tong, Fen, Li, Min-Jie, He, Xing-Jin (2017): Semenovia torilifolia is conspecific with S. malcolmii (Apiaceae) based on morphology and molecular data. Phytotaxa 321 (3): 225-237, DOI: 10.11646/phytotaxa.321.3.1, URL: http://dx.doi.org/10.11646/phytotaxa.321.3.1

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15

Nie, Lanlan, Rui Li, Jie Huang, et al. "Abietane diterpenoids from Dracocephalum moldavica L. and their anti-inflammatory activities in vitro." Phytochemistry 184 (April 30, 2021): 1–8. https://doi.org/10.1016/j.phytochem.2021.112680.

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Nie, Lanlan, Li, Rui, Huang, Jie, Wang, Lingling, Ma, Mengjie, Huang, Chunyue, Wu, Tong, Yan, Renjie, Hu, Xiao (2021): Abietane diterpenoids from Dracocephalum moldavica L. and their anti-inflammatory activities in vitro. Phytochemistry (112680) 184: 1-8, DOI: 10.1016/j.phytochem.2021.112680, URL: http://dx.doi.org/10.1016/j.phytochem.2021.112680

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Mo, Shuyuan, Jie Yin, Zi Ye, et al. "Asperanstinoids A-E: Undescribed 3,5-dimethylorsellinic acid-based meroterpenoids from Aspergillus calidoustus." Phytochemistry 190 (October 31, 2021): 1–9. https://doi.org/10.1016/j.phytochem.2021.112892.

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Mo, Shuyuan, Yin, Jie, Ye, Zi, Li, Fengli, Lin, Shuang, Zhang, Sitian, Yang, Beiye, Yao, Jun, Wang, Jianping, Hu, Zhengxi, Zhang, Yonghui (2021): Asperanstinoids A-E: Undescribed 3,5-dimethylorsellinic acid-based meroterpenoids from Aspergillus calidoustus. Phytochemistry (112892) 190: 1-9, DOI: 10.1016/j.phytochem.2021.112892, URL: http://dx.doi.org/10.1016/j.phytochem.2021.112892

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17

Li, Zhen, Baishu Li, Zhenjie Hu, et al. "The ectoparasitoid Scleroderma guani (Hymenoptera: Bethylidae) uses innate and learned chemical cues to locate its host, larvae of the pine sawyer Monochamus alternatus (Coleoptera: Cerambycidae)." Florida Entomologist 98, no. 4 (2015): 1182. https://doi.org/10.1653/024.098.0425.

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Li, Zhen, Li, Baishu, Hu, Zhenjie, Michaud, J. P., Dong, Jie, Zhang, Qingwen, Liu, Xiaoxia (2015): The ectoparasitoid Scleroderma guani (Hymenoptera: Bethylidae) uses innate and learned chemical cues to locate its host, larvae of the pine sawyer Monochamus alternatus (Coleoptera: Cerambycidae). Florida Entomologist 98 (4): 1182, DOI: 10.1653/024.098.0425, URL: http://www.bioone.org/doi/10.1653/024.098.0425

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18

Wang, Zhan, Jin Xu, Ge Song, et al. "Nutritional status and screening tools to detect nutritional risk in hospitalized patients with hepatic echinococcosis." Parasite 27, no. 74 (2020): 1–9. https://doi.org/10.1051/parasite/2020071.

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Wang, Zhan, Xu, Jin, Song, Ge, Pang, MingQuan, Guo, Bin, Xu, XiaoLei, Wang, HaiJiu, Zhou, Ying, Ren, Li, Zhou, Hu, Ma, Jie, Fan, HaiNing (2020): Nutritional status and screening tools to detect nutritional risk in hospitalized patients with hepatic echinococcosis. Parasite (Paris, France) 27 (74): 1-9, DOI: 10.1051/parasite/2020071, URL: http://dx.doi.org/10.1051/parasite/2020071

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19

Ya, Ji-Dong, Gui-Liang Zhang, Yun-Hong Tan, et al. "Two New Species of Christisonia (Orobanchaceae) from Southeastern Yunnan, China." Systematic Botany 49, no. 1 (2024): 68–76. https://doi.org/10.1600/036364424X17110456120695.

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Ya, Ji-Dong, Zhang, Gui-Liang, Tan, Yun-Hong, Zhang, Gui-Sheng, Zhang, Kun, Ping, Shan-Hu, Wang, Dong, Zhang, Wei, Cai, Jie, Randle, Christopher P., Yu, Wen-Bin (2024): Two New Species of Christisonia (Orobanchaceae) from Southeastern Yunnan, China. Systematic Botany (Basel, Switzerland) 49 (1): 68-76, DOI: 10.1600/036364424X17110456120695, URL: https://doi.org/10.1600/036364424x17110456120695

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20

Lee, Chia-Lin, Chien-Ming Wang, Hao-Chun Hu, et al. "Indole alkaloids indigodoles A-C from aerial parts of Strobilanthes cusia in the traditional Chinese medicine Qing Dai have anti-IL-17 properties." Phytochemistry 162 (March 7, 2019): 39–46. https://doi.org/10.1016/j.phytochem.2019.02.016.

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Lee, Chia-Lin, Wang, Chien-Ming, Hu, Hao-Chun, Yen, Hung-Rong, Song, Ying-Chyi, Yu, Sheng-Jie, Chen, Chao-Jung, Li, Wei-Chu, Wu, Yang-Chang (2019): Indole alkaloids indigodoles A-C from aerial parts of Strobilanthes cusia in the traditional Chinese medicine Qing Dai have anti-IL-17 properties. Phytochemistry 162: 39-46, DOI: 10.1016/j.phytochem.2019.02.016, URL: http://dx.doi.org/10.1016/j.phytochem.2019.02.016

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21

Hu, Ben, Lei-Ping Zeng, Xing-Lou Yang, et al. "Discovery of a rich gene pool of bat SARSrelated coronaviruses provides new insights into the origin of SARS coronavirus." PLoS Pathogens 13, no. 11 (2017): 1–27. https://doi.org/10.1371/ journal.ppat.1006698.

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Hu, Ben, Zeng, Lei-Ping, Yang, Xing-Lou, Ge, Xing-Yi, Zhang, Wei, Li, Bei, Shen, Xu-Rui, Zhang, Yun-Zhi, Wang, Ning, Luo, Dong-Sheng, Zheng, Xiao- Shuang, Wang, Mei-Niang, Daszak, Peter, Wang, Lin-Fa, Cui, Jie, Shi, Zheng- Li (2017): Discovery of a rich gene pool of bat SARSrelated coronaviruses provides new insights into the origin of SARS coronavirus. PLoS Pathogens 13 (11), No. 1006698: 1-27, DOI: 10.1371/journal.ppat.1006698

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22

Kerlan, Anne. "Le cinéma documentaire de Hu Jie : pour une contre-histoire de la Chine maoïste." La Revue Documentaires N° 26-27, no. 1 (2016): 87–97. http://dx.doi.org/10.3917/docu.026.0087.

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23

Green, Itzhak. "Discussion on: Jia Ma, Menghao Bai, Jie Wang, Shuai Dong, Hao Jie, Bo Hu, Lairong Yin, “A novel variable restitution coefficient model for sphere–substrate elastoplastic contact/impact process,” Mechanism and Machine Theory 202 (2024)." Mechanism and Machine Theory 205 (March 2025): 105868. https://doi.org/10.1016/j.mechmachtheory.2024.105868.

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CIM, Editor. "Letter of Retraction." Clinical & Investigative Medicine 38, no. 3 (2015): 142. http://dx.doi.org/10.25011/cim.v38i3.22708.

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It has come to our attention that the a manuscript published in CIM: JianXin J, Cha Y, ZhiPeng L, Jie X, Hao Z, Meiyuan C, ChengYi S “GOLP3 is a predictor of survival in patients with hepatocellular carcinoma” Clin Invest Med. 2014 Aug 1;37(4):E233-42 contains text identical to a manuscript published in Tumour Biology: Hu GS, Li YQ, Yang YM, Shi W, Liao AJ, Yao YH, Zeng B, Yuan J “High expression of Golgi phosphoprotein-3 is associated with poor survival in patients with hepatocellular carcinoma” Tumour Biol. 2014 Sep;35(9):8625-32. doi: 10.1007/s13277-014-2105-8. Epub 2014 May 28. For this re

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Editorial, E. "Retraction: Li Y, Li D, Ren B, Hu J, Li B, Krzton A, Li M. Determinants of differences in the activity budgets of Rhinopithecus bieti by age/sex class at Xiangguqing in the Baimaxueshan nature reserve, China. Arch Biol Sci. 2015;67(2):675-83. DOI: 10.2298/ABS140917033L." Archives of Biological Sciences 68, no. 1 (2016): 237. http://dx.doi.org/10.2298/abs160112009e.

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This is a notice of retraction of the article: Determinants of differences in the activity budgets of Rhinopithecus bieti by age/sex class at Xiangguqing in the Baimaxueshan nature reserve, China by Li Yanhong, Li Dayong, Ren Baoping, Hu Jie, Li Baoguo, Krzton Ali, Li Ming, published in the Archives of Biological Sciences Vol. 67, Issue 2, 2015. Due to inadequate exchange of information between the previous and new Editor-in-Chief of the Archives of Biological Sciences, the new Editor-in-Chief was not informed of the authors? request for withdrawal of the article. After obtaining the written r

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Shi, Jie, Rui Zhou, Shuo Wang, et al. "Abstract 1564: NEU4-mediated desialylation ignites the oncogenic receptors for the dissemination of ovarian carcinoma." Cancer Research 84, no. 6_Supplement (2024): 1564. http://dx.doi.org/10.1158/1538-7445.am2024-1564.

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Abstract Background: Glycosylation profoundly influences the interactions between cancer cells and microenvironmental stromal cells during the peritoneal disseminated metastasis of ovarian carcinoma (OC), which is the major cause of cancer-related death. Although the characteristic cancer glycoconjugates are widely used as biomarkers for cancer diagnosis, our knowledge about cancer glycome remains quite fragmented due to the technique limitations in analyzing glycan chains with tremendous structural and functional heterogeneity. Method: Given the dysregulated cancer glycome is defined by the a

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Miao, Kun, Wei Kuang, and Lifeng Wu. "Discussion of “Maximum Gradient Decision-Making for Railways Based on Convolutional Neural Network” by Hao Pu, Hong Zhang, Paul Schonfeld, Wei Li, Jie Wang, Xianbao Peng, and Jianping Hu." Journal of Transportation Engineering, Part A: Systems 147, no. 4 (2021): 07021001. http://dx.doi.org/10.1061/jtepbs.0000507.

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Liu, Zhijun, Yucun Zhou, Weilin Zhang, Jie Hou, Xueyu Hu, and Meilin Liu. "Sulfur- and Coking-Tolerant Anodes for Solid Oxide Fuel Cells." ECS Meeting Abstracts MA2022-02, no. 47 (2022): 1761. http://dx.doi.org/10.1149/ma2022-02471761mtgabs.

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Sulfur- and Coking-tolerant Anodes for Solid Oxide Fuel Cells Zhijun Liu,1 Yucun Zhou,1 Weilin Zhang,1 Jie Hou,1 Xueyu Hu,1 Meilin Liu1, * 1 School of Materials Science and Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332-0245, United States Abstract Solid oxide fuel cells (SOFCs) have potential to be one of the most efficient systems for direct conversion of a wide variety of chemical fuels into electricity. 1-3 However, the lack of sulfur- and coking-tolerant anodes still hinders the development of direct hydrocarbon-fueled SOFCs for efficient and cost-effective operation

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29

Lu, Lina, Jennifer Rui Wang, Ying C. Henderson, et al. "Abstract 3131: Anaplastic transformation model in thyroid cancer revealed by single cell lineage and fate analysis." Cancer Research 83, no. 7_Supplement (2023): 3131. http://dx.doi.org/10.1158/1538-7445.am2023-3131.

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Abstract The deadliest anaplastic thyroid cancer (ATC) often transforms from indolent differentiated thyroid cancer (DTC), however the complex intra-tumor transformation process is poorly understood. We investigated an anaplastic transformation model by dissecting both cell lineage and cell fate transitions using single cell transcriptomes and genetic alterations data of patients with different subtypes of thyroid cancer. The resulting model started from stress-responsive DTC cells to inflammatory ATC cells, to mitotic defective ATC cells and extended all the way to mesenchymal ATC cells. In p

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Khatri, Ujjwol, Neetu Dayal, Tao Shen, Xueqing Hu, Herman Sintim, and Jie Wu. "Abstract 4660: Characterization of a nicotinamide-based kinase inhibitor HSN748 for inhibition of RET-driven tumors." Cancer Research 84, no. 6_Supplement (2024): 4660. http://dx.doi.org/10.1158/1538-7445.am2024-4660.

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Abstract Rearranged during transfection (RET) is a protein tyrosine kinase that is aberrantly activated by gene fusions or mutations in many types of human cancer including thyroid cancer and non-small cell lung cancer (NSCLC). Selpercatinib (LOXO-292) and pralsetinib (BLU-667) are FDA approved RET-selective tyrosine kinase inhibitors (TKIs) being used to treat RET-altered cancer. However, these tumors develop selpercatinib/pralsetinib-resistance via acquisition of RET(G810C/R/S) mutations located at the solvent front of the ATP binding pocket. The overall goal of our research is to discover n

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Wang, Kaile, Zhenna Xiao, Yiyun Lin, et al. "Abstract 76: Reprogramming of the preinvasive breast microenvironment identified by spatial nucleus barcoding." Cancer Research 83, no. 7_Supplement (2023): 76. http://dx.doi.org/10.1158/1538-7445.am2023-76.

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Abstract Ductal-carcinoma-in-situ (DCIS) is the most common early-stage breast cancer and a non-obligate precursor to invasive breast cancer. However our understanding of the spatial microenvironment and the reprogramming of cell types in DCIS remains limited. To address this question, we developed a Spatial Nucleus Barcoding (SNuBar) method that utilizes a single oligonucleotide adaptor to preserve spatial information followed by performing single nucleus RNA sequencing. We validated the accuracy and scalability of SNuBar in cell lines and applied this method to investigate the spatial microe

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Wang, Kaile, Zhenna Xiao, Yiyun Lin, et al. "Abstract 5483: Macrospatial ecotype heterogeneity in early-stage breast cancer identified by spatial nucleus barcoding." Cancer Research 84, no. 6_Supplement (2024): 5483. http://dx.doi.org/10.1158/1538-7445.am2024-5483.

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Abstract Ductal carcinoma in situ (DCIS), the predominant form of early-stage breast cancer and a precursor to invasive breast cancer, remains inadequately understood in terms of spatial microenvironment reprogramming. In this study, we developed a Spatial Nucleus Barcoding (SNuBar) approach for single-nucleus RNA sequencing (SNuBar-RNA) that utilizes a single oligonucleotide adaptor to preserve spatial information. The accuracy and scalability of SNuBar was validated using cell line mixture experiments. We then applied SNuBar-RNA to investigate the macrospatial ecotype heterogeneity in early-

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Lu, Shun, Jie Hu, Jianhua Chen, et al. "Abstract CT053: Aumolertinib with or without chemotherapy as first line treatment in locally advanced or metastatic NSCLC with sensitizing EGFR mutations (AENEAS2)." Cancer Research 85, no. 8_Supplement_2 (2025): CT053. https://doi.org/10.1158/1538-7445.am2025-ct053.

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Abstract Introduction: Aumolertinib, a third generation selective EGFR-TKI, is standard of care for the first-line treatment in advanced or metastatic NSCLC with sensitizing EGFR mutations in China. Evidence has shown that combining EGFR-TKIs with chemotherapy can improve outcomes compared to EGFR-TKIs monotherapy. AENEAS2 (NCT04923906) is a randomized, open-label, multicenter, phase 3 study assessing the efficacy and safety of aumolertinib plus chemotherapy versus aumolertinib alone as first-line treatment in locally advanced or metastatic NSCLC with sensitizing EGFR mutations. Methods: Patie

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Wang, Kaile, Tapsi Kumar, Junke wang, et al. "Abstract 125: Archival single cell sequencing reveals persistent subclones over years to decades of DCIS progression." Cancer Research 83, no. 7_Supplement (2023): 125. http://dx.doi.org/10.1158/1538-7445.am2023-125.

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Abstract Ductal carcinoma in situ (DCIS) is a common precursor of invasive breast cancer (IBC), yet the genomic progression to recurrent disease remains poorly understood. A main contributor to this gap in knowledge arises from technical challenges with genomic profiling of formalin-fixed paraffin-embedded (FFPE) materials. To address this challenge, we developed Arc-well, the first high-throughput method that can perform single cell DNA sequencing of thousands of cells from FFPE materials and frozen tissues. Using Arc-well, we profiled genomic copy number in 27,851 single cells from 26 archiv

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Khatri, Ujjwol, Neetu Dayal, Xueqing Hu, et al. "Abstract 3851: Targeting RET solvent-front mutants with an alkynyl nicotinamide-based inhibitor." Cancer Research 83, no. 7_Supplement (2023): 3851. http://dx.doi.org/10.1158/1538-7445.am2023-3851.

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Abstract Selpercatinib (LOXO-292, LY3527723) and pralsetinib (BLU-667) are first-in-class RET-targeted cancer therapy drugs. However, secondary RET mutations that confer selpercatinib/pralsetinib resistance have been identified, necessitating development of next-generation RET Tyrosine kinase inhibitors (TKIs). While the G810C/R/S/V mutations located at the RET kinase solvent-front site were detected in selpercatinib-treated patients, it was unclear whether all of these and other potential G810 mutants are resistant to selpercatinib and pralsetinib. We profiled selpercatinib and pralsetinib on

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Pandey, Shriya, Yafeng Wang, Xueqing Hu, et al. "Abstract 7211: Proteolysis targeting chimeras (PROTACs) of oncogenic RET protein." Cancer Research 85, no. 8_Supplement_1 (2025): 7211. https://doi.org/10.1158/1538-7445.am2025-7211.

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Abstract The REarranged during Transfection (RET) kinase is an oncoprotein and a therapeutic target for RET alteration-positive cancer. Two RET-selective protein tyrosine kinase inhibitors, selpercatinib (LOXO-292) and pralsetinib (BLU-667), have been approved for treating RET-alteration-positive cancer. However, achieving a complete response with a RET kinase inhibitor remains a challenge in most patients. In cell cultures, these inhibitors increase the expression of CCDC6-RET fusion protein, which may affect their effectiveness at low concentrations. To tackle this problem, we synthesized an

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Whittingham, Stan, BEN PEI, Isik Buyuker, Krystal Lee, Fengxia Xin, and Hui Zhou. "(Invited, Digital Presentation) Pushing the Limits of High Nickel NMC Cathodes." ECS Meeting Abstracts MA2022-01, no. 2 (2022): 334. http://dx.doi.org/10.1149/ma2022-012334mtgabs.

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Lithium-ion batteries now dominate electrochemical energy storage for vehicle propulsion and grid storage in addition to portable electronics. In 2022, they celebrate their 50th anniversary, and yet still achieve only 25% of their theoretical energy density. The dominant anode and cathode today are graphitic carbon and the layered NMC oxides, LI[NiMnCoAl]O2. Both need improving. Most of the carbon in the anode must go, and the NMCs need pushing to their limit and at the same time eliminating cobalt. I will today discuss the challenges faced as we push the limits of the NMCs to their limits, &g

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Jia, Guochong, Jie Ping, Ran Tao, et al. "Abstract 2286: Integrating multi-ancestry genomic and proteomic data to identify blood risk biomarkers and target proteins for breast cancer genetic risk loci." Cancer Research 85, no. 8_Supplement_1 (2025): 2286. https://doi.org/10.1158/1538-7445.am2025-2286.

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Abstract Genome-wide association studies (GWAS) have identified more than 200 risk loci for breast cancer. However, target genes and their encoded proteins in these loci remain largely unknown. In this study, we utilized genetic prediction models for 1, 350 circulating proteins derived from individuals of African (n= 1, 871) and European (n= 7, 213) ancestry to investigate genetically predicted protein levels in association with breast cancer risk among females of African (n=40, 138), Asian (n= 137, 677), and European (n=247, 173) ancestry. We identified 70 blood protein biomarkers associated

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Zhang, Li, Heng Wu, Karyssa Palopo, et al. "Abstract 1147: A novel anti-Galectin-3 antibody therapeutic for the treatment of triple negative breast cancer." Cancer Research 82, no. 12_Supplement (2022): 1147. http://dx.doi.org/10.1158/1538-7445.am2022-1147.

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Abstract About 43,600 women in the U.S. are expected to die in 2021 from breast cancer. Triple negative breast cancer (TNBC), which accounts for approximately 15% of all breast cancers, is diagnosed by exclusion of expression and/or amplification of three biomarkers (estrogen receptor [ER], progesterone receptor [PR], and human epidermal growth factor receptor 2 [HER2]).Characterized by a high risk of relapse (one half of patients with early stages experience recurrence), short overall survival and progression-free survival (life expectancy of few months after failure of first-line chemotherap

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Fu, Michael C. "Simulation-Based Algorithms for Markov Decision Processes: Monte Carlo Tree Search from AlphaGo to AlphaZero." Asia-Pacific Journal of Operational Research 36, no. 06 (2019): 1940009. http://dx.doi.org/10.1142/s0217595919400098.

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AlphaGo and its successors AlphaGo Zero and AlphaZero made international headlines with their incredible successes in game playing, which have been touted as further evidence of the immense potential of artificial intelligence, and in particular, machine learning. AlphaGo defeated the reigning human world champion Go player Lee Sedol 4 games to 1, in March 2016 in Seoul, Korea, an achievement that surpassed previous computer game-playing program milestones by IBM’s Deep Blue in chess and by IBM’s Watson in the U.S. TV game show Jeopardy. AlphaGo then followed this up by defeating the world’s n

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Huang, Huaizhi (Gilbert), Chunling Hu, Jie Na, et al. "Abstract PR09: Functional and clinical characterization of hypomorphic missense variants in the BRCA2 cancer predisposition gene." Cancer Research 84, no. 3_Supplement_1 (2024): PR09. http://dx.doi.org/10.1158/1538-7445.advbc23-pr09.

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Abstract Many germline BRCA2 missense variants of uncertain significance (VUS) remain to be clinically classified as pathogenic or benign. Here we identify 70 missense VUS in the DNA binding domain (DBD) of BRCA2 that partially reduced homologous recombination DNA repair activity of the protein in a homology directed DNA repair cell-based assay. CRISPR/cas9-based knockin of these variants reduced cell survival of haploid cells and conferred increased sensitivity to the PARP inhibitor Olaparib. Sequence alignment analysis found that the variants were highly conserved across species from pufferf

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He, Daochuan, Yiren Xiao, Zhuo Li, et al. "Abstract 5461: BG-C477, a novel topoisomerase 1 inhibitor-based ADC, exhibits antitumor activity in carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5)-expressing preclinical models." Cancer Research 85, no. 8_Supplement_1 (2025): 5461. https://doi.org/10.1158/1538-7445.am2025-5461.

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Abstract CEACAM5 (CEA) is a cell surface glycoprotein highly expressed in many cancers, including colorectal cancer (CRC), gastric cancer (GC), lung and pancreatic cancers. BG-C477 is a novel ADC that is composed of a CEACAM5-specific antibody conjugated to Top1i payloads (drug-to-antibody ratio = 8) via a cleavable linker. It remains stable in human plasma and mice blood circulation. BG-C477 showed specific binding to CEA-expressing MKN45 cells and stronger internalization activity compared to anti-CEA DM4 ADC. BG-C477 exhibited robust and CEA-dependent cytotoxicity in cell lines with differe

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Wang, Jian, Ning Zhang, Yun Liang, et al. "Abstract CT084: Prediction of surufatinib treatment outcome in advanced grade 3 neuroendocrine tumors (NET G3) patients." Cancer Research 85, no. 8_Supplement_2 (2025): CT084. https://doi.org/10.1158/1538-7445.am2025-ct084.

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Abstract Background: Prognosis of NET G3 patients is usually poor and there is currently no standard treatment. Preliminary studies have suggested antiangiogenic TKIs could improve PFS for these patients. This study aims to evaluate the efficacy of surufatinib in advanced NET G3 via Cox regression analysis and identify predictive factors. Methods: A national multi-center study was carried in advanced NET G3 patients who were treated with surufatinib. PFS was the primary endpoint. Logistic regression and Cox proportional-hazards models were used to assess the predictive factors of PFS. The foll

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NURALIEV, MAXIM S., ANDREY N. KUZNETSOV, SVETLANA P. KUZNETSOVA, and CHI-MING HU. "Ardisia patentiradiosa (Primulaceae), a new species from southern Vietnam." Phytotaxa 522, no. 1 (2021): 63–67. http://dx.doi.org/10.11646/phytotaxa.522.1.7.

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Ardisia patentiradiosa C.M. Hu & Nuraliev (Primulaceae) collected from montane forest of Gia Lai Province, Vietnam, is described and illustrated. Its distinguishing characters from its closest relatives, Ardisia gracilenta C.M. Hu & J.E. Vidal and A. pitardii C.M. Hu & J.E. Vidal, are discussed.

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Hu, Jie, Haoran Tang, Feng Xie, Yue Zhang, Shidong Jia, and Jian Zhou. "Abstract 1020: Tissue-informed ctDNA MRD assay detects post-surgery minimal residual disease in HCC patients." Cancer Research 83, no. 7_Supplement (2023): 1020. http://dx.doi.org/10.1158/1538-7445.am2023-1020.

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Abstract Introduction: Residual disease detection is a significant clinical need in post-surgery treatment of resectable hepatocellular carcinoma (HCC) patients. Previous NGS-based studies targeting fixed genomic regions had reported that circulating tumor DNA (ctDNA) could provide evidence for prognosis prediction during HCC treatment. However, the sensitivity of methods was limited and could not reach the threshold of minimal residual disease (MRD) test. Here we reported a baseline tissue -informed ctDNA NGS assay, detecting MRD in HCC patients who received hepatectomy and predicted prognosi

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Yang, Cuiqing, Xiaohui Shao, Feng Zhou, et al. "Abstract 6343: A multispecific T cell engager binding to both membrane proximal and membrane distal epitopes of MSLN with low affinity CD3 for the treatment of AML and solid tumors." Cancer Research 82, no. 12_Supplement (2022): 6343. http://dx.doi.org/10.1158/1538-7445.am2022-6343.

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Abstract Purpose: The effective treatment of AML and solid tumors remains an unmet medical need. Mesothelin (MSLN) is a glycophosphatidylinositol-linked tumor antigen overexpressed in a variety of malignancies, including AML and solid tumors, such as mesothelioma, cholangiocarcinoma, ovarian, pancreatic, lung, esophageal, gastric, colorectal, endometrial and triple-negative breast cancer. Early signs of clinical efficacy with MSLN-targeting agents have validated MSLN as a promising target for therapeutic intervention, but therapies with improved efficacy are still needed. CD3-based T cell enga

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Cheng, Ka Ming, Gui yun Wu, Kowk Kuen Cheung, Xiao-Ling Shen, Ying-Jie Hu та Ki Lui. "Abstract 4676: 11α-O-2-methylbutanoyl-12β-O-tigloyl-tenacigenin B (MT2) is a novel paclitaxel chemosensitizer to inhibit growth in Taxol non-resistant and Taxol resistant cancers". Cancer Research 84, № 6_Supplement (2024): 4676. http://dx.doi.org/10.1158/1538-7445.am2024-4676.

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Abstract 11α-O-2-methylbutanoyl-12β-O-tigloyl-tenacigenin B (MT2) is a single molecule isolated from a traditional Chinese Medicinal herb Marsdenia tenacissima (MT). Recently, our group has isolated a few single molecules from the MT herb, they have shown significant anti-tumor activity in vitro and MT2 has the highest potential among all. We have performed MTT viability assay and clonogenic assay to demonstrate that MT2-alone is non-cytotoxic, but the cytotoxicity of the paclitaxel+MT2 combination treatment was more significant than that of paclitaxel, a microtubule stabilizing chemotherapeut

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Li, Jiaxin. "Research on the Origin and Evolution of Hu Jia." Lecture Notes in Education Psychology and Public Media 39, no. 1 (2024): 82–87. http://dx.doi.org/10.54254/2753-7048/39/20240677.

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The Silk Road originated from the Western Han Dynasty. The word Silk indicates that it was originally a trade route, which eventually developed into a bridge for economic, cultural, and artistic exchanges between the East and the West. It connected Central Asia, West Asia, and countries around the Mediterranean, allowing different countries and different styles of music and dance to collide, promoting music exchanges and development in the surrounding countries along the Silk Road. As for the introduction of musical instruments and music into the Central Plains, the Silk Road has undoubtedly h

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Ouyang, Jie, Yifen Wu, Pengfei Qian, et al. "Abstract P2-12-22: A multicenter, single-arm, phase II clinical trial of oral CDK4/6 inhibitor darciclib in combination with endocrine therapy in adjuvant treatment for hormone receptor-positive, HER2-negative female breast cancer." Clinical Cancer Research 31, no. 12_Supplement (2025): P2–12–22—P2–12–22. https://doi.org/10.1158/1557-3265.sabcs24-p2-12-22.

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Abstract Background: Although the role of endocrine therapy in the adjuvant treatment of HR+/HER2- breast cancer has been established, Early HR positive and HER2 negative breast cancer show a long-term risk of recurrence. Studies have shown that about 20% of patients experience recurrence and metastasis after receiving adjuvant endocrine therapy for 5 years. CDK4/6 inhibitor combined with endocrine therapy for HR+/HER2- breast cancer has been proven to have synergistic effects. Previous studies have shown that Abemaciclib and ribociclib can reduce the risk of recurrence and increase iDFS in ea

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Hu, Weilei, Yifei Bian, Zihan Zhao, Shian Ouyang, Jie P. Li, and Hongbin Ji. "Abstract B005: Identification of tumor-reactive TILs from lung cancer organoids co-culture through ruthenium-based proximity labeling." Cancer Immunology Research 13, no. 2_Supplement (2025): B005. https://doi.org/10.1158/2326-6074.io2025-b005.

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Abstract Tumor-reactive T cells are crucial for the success of tumor-infiltrating lymphocyte (TIL) therapies. Currently, identifying tumor-reactive T cells and their corresponding TCRs typically relies on pre-characterized tumor antigens. Many solid tumors, including lung cancer, exhibit considerable heterogeneity and consequently possess diverse tumor antigenic profiles. Markers such as PD-1 and CD39 are commonly used to identify tumor-reactive TILs, yet these empirically derived markers can produce false positives or fail to capture rare tumor-reactive populations. We here used an unbiased r

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