Log in

Relevant bibliographies by topics / HU Protein / Dissertations / Theses

To see the other types of publications on this topic, follow the link: HU Protein.

Dissertations / Theses on the topic 'HU Protein'

Author: Grafiati

Published: 4 June 2021

Last updated: 6 September 2023

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 34 dissertations / theses for your research on the topic 'HU Protein.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Hu, Hong-gang [Verfasser]. "Das Protein DEK im Chromatin menschlicher Zellen / Hong-gang Hu." Aachen : Shaker, 2008. http://d-nb.info/1162791322/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Nguyen, Chi Mai. "Post-transcriptional regulation during spermatogenesis : Role of the RNA-binding protein hu." Toulouse 3, 2008. http://thesesups.ups-tlse.fr/365/.

Full text

Abstract:

La spermatogenèse est un processus élaboré permettant d'une part le maintien de cellules souches par divisions mitotiques et d'autre part la production de spermatozoïdes par différenciation. Au cours des dernières étapes de la différenciation, la chromatine se compacte, ne laissant plus à la cellule la possibilité de transcrire ses gènes. Du fait de l'arrêt brutal de la transcription, bien avant la fin du processus de différenciation, la cellule germinale utilise le stock d'ARN messagers (ARNm) préexistants pour finaliser sa différenciation. Ce phénomène repose sur la régulation fine du stocka

APA, Harvard, Vancouver, ISO, and other styles

3

Kokorelis, Steve H. "Biochemical Analysis of Putative Single-Stranded Nucleic Acid Binding Proteins in Porphyromonas gingivalis." VCU Scholars Compass, 2017. http://scholarscompass.vcu.edu/etd/4833.

Full text

Abstract:

Proteins that bind to both DNA and RNA embody the ability to perform multiple functions by a single gene product. These nucleic acid binding proteins in prokaryotes can play a vital role in many cellular processes, including replication, transcription, gene expression, recombination, and repair, to name a few. Nucleic acid binding proteins have unique functional characteristics that stem from their structural attributes that have evolved in a widely-conserved manner. In Escherichia coli (E. coli), the highly-conserved histone-like protein, HU, which predominates as a heterodimer of HUα and HU

APA, Harvard, Vancouver, ISO, and other styles

4

Berger, Michael [Verfasser]. "The role of the chromatin protein HU in organization of transcription foci and coordination of genomic transcription in Escherichia coli / Michael Berger." Bremen : IRC-Library, Information Resource Center der Jacobs University Bremen, 2008. http://d-nb.info/1034966677/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Furrer, Marie-Pierre. "Fonction des gènes de la famille elav/Hu dans la différenciation du système nerveux chez Xenopus laevis et Drosophila melanogaster." Paris 11, 2000. http://www.theses.fr/2000PA112370.

Full text

Abstract:

Le but de cette thèse était de comprendre le rôle des protéines de la famille ELAV/Hu dans le développement, le maintien et la fonction des neurones par l’analyse phénotypique de mutants de dérégulation d'elav/Hu sur deux organismes modèles. Chez le xénope, nous avons montré que 3 homologues de la famille elav/Hu (elrB, elrC et elrD) sont exprimés de façon différentielle au cours du développement du système nerveux, suggérant un rôle dans différentes phases de la maturation des neurones et la définition de différents sous-domaines neuraux. La dérégulation de l’expression d'elrB dans les embryo

APA, Harvard, Vancouver, ISO, and other styles

6

Le, Meur Rémy. "Etude structurale du mécanisme d'échange de chaînes des dimères de la protéine HU d'E. coli." Thesis, Orléans, 2015. http://www.theses.fr/2015ORLE2004/document.

Full text

Abstract:

HU est une protéine bactérienne de type histone impliquée dans de nombreuses fonctions biologiques telles que la compaction, la transcription, la réplication et la réparation de l'ADN. Chez E. coli, il existe trois espèces dimériques de HU (HUα2, HUβ2 et HUαβ) ayant des rôles biologiques distincts. La formation de l'hétérodimère repose sur un échange de chaines peptidiques entre les homodimères. Un mécanisme modèle a été proposé par Ramstein et collaborateurs (J.M.B. 331, 101-121 2003) et a servi de point de départ a ce travail. Dans ce modèle, les homodimères transitent d'une conformation nat

APA, Harvard, Vancouver, ISO, and other styles

7

Buell, Alexander Kai. "On the kinetics of protein misfolding and aggregation." Thesis, University of Cambridge, 2011. https://www.repository.cam.ac.uk/handle/1810/270324.

Full text

Abstract:

Protein (mis)folding into highly ordered, fibrillar structures, amyloid fibrils, is a hallmark of several, mainly neurodegenerative, disorders. The mechanism of this supra-molecular self-assembly reaction, as well as its relationship to protein folding are not well understood. In particular, the molecular origin of the metastability of the soluble state of proteins with respect to the aggregated states has not been clearly established. In this dissertation, it is demonstrated, that highly accurate kinetic experiments, using a novel biosensing method, can yield fundamental insight into the dyna

APA, Harvard, Vancouver, ISO, and other styles

8

Zhang, Chengsheng. "Functional studies of HIV-1 Vpr protein and development of hu-PBL-SCID/beige mouse model for the studies of HIV-1 infection in vivo." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape17/PQDD_0001/NQ29133.pdf.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Zhu, Hui. "Hu Proteins, A Novel Family of Neuron-Specific Regulators for Post-Transcriptional RNA Processing." Case Western Reserve University School of Graduate Studies / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=case1175209225.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

BOUBRIK, FATIMA. "Role pleiotropique de la proteine hu chez escherichia coli." Paris 11, 1995. http://www.theses.fr/1995PA112233.

Full text

Abstract:

Hu est parmi les proteines affines a l'adn la plus abondante d'e. Coli. C'est un dimere constitue de deux sous-unites, qui existe sous trois formes: alpha beta, alpha 2 et beta 2. Hu ne reconnait pas de sequence particuliere. Il a ete montre recemment qu'hu reconnait des structures cruciformes de l'adn. Par ailleurs, l'effet d'hu sur la conformation de l'adn a ete bien etabli. Nous avons etudie le role d'hu dans trois mecanismes: la replication, la recombinaison et la reparation ; ainsi que la compensation d'hu par ihf. Nos resultats ont montre qu'ihf ne compense pas l'absence d'hu dans la cel

APA, Harvard, Vancouver, ISO, and other styles

11

Sun, Xia. "Transcriptomic and functional analysis of genes encoding pan-neuronal RNA binding proteins in Drosophila." Thesis, Paris 11, 2014. http://www.theses.fr/2014PA11T036.

Full text

Abstract:

La régulation post-transcriptionnelle joue un rôle essentiel dans le système nerveux, de l’assemblage à la fonction. Chez les métazoaires, la famille multigénique ELAV / Hu code pour des protéines de liaison à l'ARN produites dans les neurones et impliqués dans cette régulation. Le gène elav (embryonic lethal abnormal visual system) code pour une protéine essentielle produite dans tous les neurones et est présent seulement chez les diptères. L’élucidation des fonctions des plus anciens paralogues de drosophile, fne (found in neurons) et rbp9 (RNA binding protein 9), a fait l'objet de ce travai

APA, Harvard, Vancouver, ISO, and other styles

12

BENSAID, ABDERAZZAK. "Relations entre les topoisomerases et la proteine hu chez escherichia coli." Paris 11, 1995. http://www.theses.fr/1995PA112415.

Full text

Abstract:

Si hu contribue a la formation des structures de type nucleosomique dans la bacterie, son absence devrait modifier l'equilibre des topoisomerases responsable du maintien de la superhelicite non contrainte. Les differents resultats obtenus montrent effectivement une augmentation de l'activite relaxante de la topoisomerase i inversement proportionnelle a la quantite d'hu presente dans la cellule bacterienne. Nous avons egalement observe une diminution de la synthese de la sous-unite gyra dans les doubles mutants d'hu. Ces variations constatees contribuent a eliminer l'exces de la superhelicite n

APA, Harvard, Vancouver, ISO, and other styles

13

PINSON, KERAMBRUN VALERIE. "Differents modes de fixation de la proteine hu d'escherichia coli a l'adn." Paris 11, 2001. http://www.theses.fr/2001PA112078.

Full text

Abstract:

Hu est la proteine affine a l'adn la plus abondante chez e. Coli qui reconnait une structure particuliere de l'adn. En se liant a l'adn elle modifie la conformation de l'adn, ce faisant elle intervient dans de nombreux mecanismes moleculaires essentiels pour la survie de la bacterie. Hu est tres conservee et existe sous trois formes dimeriques (, 2 et 2) associees a une phase de croissance bien precise. Nous avons developpe un systeme pour optimiser la surproduction et la purification des dimeres sous leur forme native depourvue de contamination nucleasique. Nous avons determine les caracteris

APA, Harvard, Vancouver, ISO, and other styles

14

Claret, Laurent. "Regulation de la synthese de la proteine de type-histone hu chez escherichia coli." Paris 6, 1997. http://www.theses.fr/1997PA066276.

Full text

Abstract:

La proteine hu d'escherichia coli appartient a un groupe de proteines abondantes et affines a l'adn que l'on qualifie de type-histone, en raison des proprietes qu'elle partage avec les histones des eucaryotes. Cette proteine hu participe au maintien du niveau de superhelicite du chromosome bacterien au sein du nucleoide. D'autre part hu intervient dans la replication, la transcription, la transposition, la recombinaison et la reparation de l'adn. Ses roles dans la bacterie sont donc consideres comme relativement divers. L'etude de la regulation de la synthese d'hu nous a amene a aborder la reg

APA, Harvard, Vancouver, ISO, and other styles

15

PAINBENI, ERIC. "Implication de la proteine de type-histone hu d'escherichia coli dans les modifications liees a la membrane bacterienne." Paris 6, 1996. http://www.theses.fr/1996PA066655.

Full text

Abstract:

La proteine hu d'escherichia coli est le prototype d'une nouvelle classe de proteines bacterienne de faible poids moleculaire, affines a l'adn comprenant hu mais aussi ihf, fis et h-ns. La proteine hu joue un role pleiotropique dans la cellule puisqu'elle intervient au niveau de la replication, de la transposition, de l'inversion genique ou encore de la reparation. Nous avons mis en evidence deux mecanismes reliant hu, proteine de type histone, a des modifications de la membrane bacterienne. Dans un premier temps, la deregulation de la synthese d'hu par transformation d'une souche sauvage par

APA, Harvard, Vancouver, ISO, and other styles

16

Hinman, Melissa N. "The Function and Regulation of Neurofibromatosis Type 1 Exon 23a Alternative Splicing." Case Western Reserve University School of Graduate Studies / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=case1390500738.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

LORIGA, ROBERTA. "Effetti dell'agonista cannabinoide HU-210 e dell'antagonista SR141716A nel forced swimming test: studio biochimico e comportamentale." Doctoral thesis, Università degli Studi di Cagliari, 2011. http://hdl.handle.net/11584/266264.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Coste, Franck. "Etude cristallographique d'adduits du platine dans l'adn et contribution a l'etude de la reconnaissance entre un adn platine a un site d(gpg) et la proteine hu d'escherichia coli." Orléans, 1999. http://www.theses.fr/1999ORLE2030.

Full text

Abstract:

L'adn est une molecule polymorphe dont les differentes conformations sont liees a des fonctions cellulaires precises. Elle est sensible a certains agents physiques et chimiques. Cette propriete est exploitee dans le cas de la chimiotherapie ou un agent chimique comme le cis-dichlorodiamminoplatine (ii) (cis-ddp) modifie, en se fixant a l'adn, la conformation de la double helice ce qui le rend particulierement toxique pour les cellules en division rapide. Etant donne que la cytotoxicite du cis-ddp n'a pas encore pu etre correlee au type d'adduit forme sur l'adn, il est important d'avoir un aper

APA, Harvard, Vancouver, ISO, and other styles

19

Tavares, Lucas Alves. "O envolvimento da proteína adaptadora 1 (AP-1) no mecanismo de regulação negativa do receptor CD4 por Nef de HIV-1." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/17/17136/tde-06012017-113215/.

Full text

Abstract:

O Vírus da Imunodeficiência Humana (HIV) é o agente etiológico da Síndrome da Imunodeficiência Adquirida (AIDS). A AIDS é uma doença de distribuição mundial, e estima-se que existam atualmente pelo menos 36,9 milhões de pessoas infectadas com o vírus. Durante o seu ciclo replicativo, o HIV promove diversas alterações na fisiologia da célula hospedeira a fim de promover sua sobrevivência e potencializar a replicação. A rápida progressão da infecção pelo HIV-1 em humanos e em modelos animais está intimamente ligada à função da proteína acessória Nef. Dentre as diversas ações de Nef está a regula

APA, Harvard, Vancouver, ISO, and other styles

20

Hu, Hong-gang [Verfasser]. "Das Protein DEK im Chromatin menschlicher Zellen / vorgelegt von Hong-gang Hu." 2005. http://d-nb.info/974330825/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Hsu, Chiau Wei, and 許喬威. "Study of the interaction of Lon protease with HU protein via optical tweezers." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/87669355585382655945.

Full text

Abstract:

碩士<br>國立陽明大學<br>生醫光電工程研究所<br>95<br>We setup an optical manipulation system to trap a polystyrene particle via optical tweezers and measured the transverse optical spring constant by analyzing the Brownian motion of the trapped particle driven by thermal fluctuation. In our experiments, the transverse optical spring constant was measured to be approximately 115±1pN/mm when a polystyrene particle (diameter =2.88μm) was trapped with a 19mW IR laser beam (wavelength = 1064nm) focused by an oil-immersion objective lens with a numerical aperture (NA) of 1.24. In biological application, we focused on

APA, Harvard, Vancouver, ISO, and other styles

22

McCarthy, Peter James. "Investigation into the molecular function of the neuronal Hu RNA binding protein, HuCsv1." Thesis, 2011. http://hdl.handle.net/2440/70239.

Full text

Abstract:

Of the four Hu genes found in most vertebrates (HuA, HuB, HuC and HuD), all except HuA exhibit mRNA and protein expression that is essentially restricted to post-mitotic neurons of the developing and adult nervous systems. Spatial and temporal examination of individual “neuronal Hu” (nHu = HuB, HuC and HuD) proteins in brain tissue suggests nHu proteins may play a functional role during neuronal differentiation; as RNA-binding proteins, the nHu proteins may participate in gene regulatory events that are essential for acquisition of the neuronal phenotype. We have identified a number of candid

APA, Harvard, Vancouver, ISO, and other styles

23

Hu, Yuhui [Verfasser]. "Cell array based functional analysis of human chromosome 21 proteins : Protein localization & programmed cell death (apoptosis) / vorgelegt von Yuhui Hu." 2006. http://d-nb.info/983475563/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Chen, Tse-An. "ATP-dependent degradation in Vitro of histone-like HU protein from Bacillus subtilis by Lon protease." 2004. http://www.cetd.com.tw/ec/thesisdetail.aspx?etdun=U0001-1607200409081200.

Full text

APA, Harvard, Vancouver, ISO, and other styles

25

Chen, Tse-An, and 陳則安. "ATP-dependent degradation in Vitro of histone-like HU protein from Bacillus subtilis by Lon protease." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/64195906917643898547.

Full text

Abstract:

碩士<br>國立臺灣大學<br>生化科學研究所<br>92<br>HU, a prokaryotic histone-like protein, associates with bacterial nucleoids and plays architectural roles in replication initiation, transcription regulation and site-specific recombination. To gain an insight into the role of Lon protease in regulation of HU, the purified Bt-Lon was incubated with HU of Bacillus subtilis (Bs-HU). Lon selectively degraded Bs-HU in an ATP-dependent manner, thus confirming the ability of Lon to directly recognize and degrade specific substrates. Cleavage occurred at Leu44-Ile45 and Ala57-Arg58 peptide bonds in the early period of

APA, Harvard, Vancouver, ISO, and other styles

26

Ghosh, Soumitra. "Nucleoid-associated Proteins of Mycobacterium tuberculosis : Insights into their Functions." Thesis, 2014. https://etd.iisc.ac.in/handle/2005/4561.

Full text

Abstract:

Bacteria face the challenging task of compacting their chromosomes to accommodate them in a small cytoplasmic volume and at the same time maintaining the nucleoids in a highly organized and dynamic state for transcription, DNA replication, and chromosome partitioning to take place with accuracy and speed. DNA also has to be protected from damage to preserve the genetic information. The structure and organization of the bacterial chromatin is shaped by compacting forces, such as DNA supercoiling, macromolecular crowding, and by nucleoid-associated proteins (NAPs). The NAPs are often referred to

APA, Harvard, Vancouver, ISO, and other styles

27

Berger, Michael. "The role of the chromatin protein HU in organization of transcription foci and coordination of genomic transcription in Escherichia coli /." 2007. http://www.jacobs-university.de/phd/files/1193312748.pdf.

Full text

Abstract:

Thesis (Ph.D.)--Jacobs University Bremen, 2007.<br>School of Engineering and Science. "Doctor of Philosophy in Biochemistry." Includes bibliographical references (leaves 100-105). Also available online.

APA, Harvard, Vancouver, ISO, and other styles

28

Hu, Bin [Verfasser]. "Identification of the paralemmin protein family and initial characterization of palmdelphin, a member of the family / vorgelegt von Bin Hu." 2001. http://d-nb.info/964992736/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Bhowmick, Tuhin. "Crystal Structure Of Mycobacterium Tuberculosis Histone Like Protein HU And Structure Based Design Of Molecules To Inhibit MtbHU-DNA Interaction : Leads For A New Target. Structure Aided Computational Analysis Of Metal Coordinated Complexes Containing Amino Acids And Organic Moieties Designed For Photo Induced DNA Cleavage." Thesis, 2012. https://etd.iisc.ac.in/handle/2005/2469.

Full text

Abstract:

In bacteria, nucleoid associated proteins (NAPs) represent a prominent group of global regulators that perform the tasks of genome compaction, establishing chromosomal architecture and regulation of various DNA transactions like replication, transcription, recombination and repair. HU, a basic histone like protein, is one of the most important NAPs in Eubacteria. Mycobacterium tuberculosis produces a homodimeric HU (MtbHU), which interacts with DNA non-specifically through minor groove binding. Exploration for essential genes in Mtb (H37Rv) through transposon insertion has identified HU coding

APA, Harvard, Vancouver, ISO, and other styles

30

Bhowmick, Tuhin. "Crystal Structure Of Mycobacterium Tuberculosis Histone Like Protein HU And Structure Based Design Of Molecules To Inhibit MtbHU-DNA Interaction : Leads For A New Target. Structure Aided Computational Analysis Of Metal Coordinated Complexes Containing Amino Acids And Organic Moieties Designed For Photo Induced DNA Cleavage." Thesis, 2012. http://hdl.handle.net/2005/2469.

Full text

Abstract:

In bacteria, nucleoid associated proteins (NAPs) represent a prominent group of global regulators that perform the tasks of genome compaction, establishing chromosomal architecture and regulation of various DNA transactions like replication, transcription, recombination and repair. HU, a basic histone like protein, is one of the most important NAPs in Eubacteria. Mycobacterium tuberculosis produces a homodimeric HU (MtbHU), which interacts with DNA non-specifically through minor groove binding. Exploration for essential genes in Mtb (H37Rv) through transposon insertion has identified HU coding

APA, Harvard, Vancouver, ISO, and other styles

31

Dey, Debayan. "Crystal Structures of Native and AdoMet Bound rRNA Methyltransferase from Sinorhizobium meliloti : Structural Insights into rRNA Recognition. Evolutionary, Structural and Functional Studies on Nucleoid-Associated Proteins HU and IHF." Thesis, 2016. http://etd.iisc.ac.in/handle/2005/4062.

Full text

Abstract:

DNA- and RNA-binding proteins play a central role in gene regulation, which includes transcriptional control, alternative splicing, post-translational and transcriptional modifications like methylation and acetylation among other roles. In this way, they control most of the working machinery of the cell in direct or indirect manner. Although more than 60 years ago the structure of DNA was proposed by Watson and Crick, our understanding of how RNA- and DNA-binding proteins interact with the genome and transcriptome remains scarce. One of the most important questions in biology is how a large nu

APA, Harvard, Vancouver, ISO, and other styles

32

Hövel, Thorsten. "Charakterisierung der Funktion des Tight Junction Proteins hu-CLDN1 und seine Bedeutung bei der Tumorgenese." Doctoral thesis, 2001. https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-1409.

Full text

Abstract:

Vor 2 Jahren wurden erstmals die wahrscheinlich wichtigsten Tight Junction Proteine, Claudin-1 und -2 in der Maus beschrieben. An Hand von Sequenzhomologien konnten bis heute dieser 4 Transmembrandomänen Proteinfamilie 18 Mitglieder mit unterschiedlichen Gewebeverteilungen zugeordnet werden. Parallel zum murinen Claudin-1 wurde von (Swisshelm et al. 1999) das humane Claudin-1 mit einer 91 prozentigen Sequenzhomologie zum murinen Protein isoliert und molekulargenetisch beschrieben. In der überwiegenden Mehrzahl von Brusttumorzellinien ist die Expression von hu-CLDN1 verloren gegangen. In der vo

APA, Harvard, Vancouver, ISO, and other styles

33

Hövel, Thorsten [Verfasser]. "Charakterisierung der Funktion des Tight-junction-Proteins hu-CLDN1 und seine Bedeutung bei der Tumorgenese / vorgelegt von Thorsten Hövel." 2002. http://d-nb.info/96600020X/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

34

Bartels, Frank [Verfasser]. "Isolierung und funktionelle Charakterisierung Histon-ähnlicher Proteine aus Pseudomonas putida : In-vitro-Untersuchungen zur Rolle von HU und IHF bei der Aktivierung σ54-abhängiger Promotoren des TOL-Plasmids / von Frank Bartels". 2001. http://d-nb.info/962722677/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!