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N., W. H., Chou Hsun-ch'u (Zhou Xun chu), Yen Chieh (Yan Jie), Wu Hsiu-ch'eng (Wu Xiu cheng), and Yao Sung (Yao Song). "T'ang-jen i-shih hui-pien (Tang ren yi shi hui bian)." Chinese Literature: Essays, Articles, Reviews (CLEAR) 18 (December 1996): 234. http://dx.doi.org/10.2307/495649.
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WU, Peichen. "Traveling Japan, Writing Japan：The Translation and Publishing of the Travelogue Wareteki Nihon." Border Crossings: The Journal of Japanese-Language Literature Studies 13, no. 1 (December 30, 2021): 53–60. http://dx.doi.org/10.22628/bcjjl.2021.13.1.53.
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The travelogue Wareteki Nihon was published in December 2018 by Hakushui Sha, and included the work of eighteen Taiwanese writers from various generations. All their works in the text relate to their travels in Japan. These Taiwanese writers are Kan Yao-Ming, Ko Yu-fen, Huang Li-Chun, Wang Sheng-Hong, Jiang E, Chen Bo-Chin, Hu Mu-Ching, Sheng Hao-We, Chu He-Chih, Wu Ming-Yi, Lu Hui-Hsin, Yi Ge-Yan, Yen Shu-Hsia, and Liu Shu-Hui, whose works in this anthology depict Japanese scenery, culture and literature, and so on. This paper will focus on how this publishing project started, the process of producing this travelogue, and the evaluations and responses of Japan’s literary circle and the mass media to it after its publication in Japan.
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HONG, XIAO-YUE, ZHI-QIANG ZHANG, and GUO-QING LI. "Tetranychidae of China: a review of progress, with a checklist." Zoosymposia 4, no. 1 (June 30, 2010): 133–50. http://dx.doi.org/10.11646/zoosymposia.4.1.9.
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This paper reviews the research on the family Tetranychidae in China, with an updated checklist of 212 species belonging to 28 genera. Major contributions to the Chinese fauna of the Tetranychidae were made by Wang Hui-Fu and her colleagues who discovered and described about 40 species, Ma En-Pei and Yuan Yi-Lan who discovered over 30 species, and Tseng Yi-Hsiung and his co-authors who added over 20 new species. There have been a lot of studies on the biology and control of the spider mites in China and recent studies are briefly reviewed.
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Xiaowei, Yang, and Wang Yanfeng. "Study on seismic and shock absorption performance of Yi Ci Hui stone pillar." IOP Conference Series: Earth and Environmental Science 676, no. 1 (February 1, 2021): 012033. http://dx.doi.org/10.1088/1755-1315/676/1/012033.
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장수연 and kwandong MIN. "A study of manuscript ≪HUI-JIN-YAN-YI≫ at the National Assembly Library." Journal of Chinese Language and Literature ll, no. 61 (December 2012): 267–91. http://dx.doi.org/10.15792/clsyn..61.201212.267.
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Kobzev, Artem I. "The First Interpretations of the Yi-jing in the West and in Russia." Voprosy Filosofii, no. 5 (2021): 182–98. http://dx.doi.org/10.21146/0042-8744-2021-5-182-198.
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The Yi-jing易經(Canon of Changes), or Zhou yi周易(All-Encompassing Cyclical Changes of the Zhou [era]), is “the book of books” of Chinese culture, which is also claimed to be the primary source of binary numeration, first described in the West by Leibniz. He was always interested in China, familiar with the binary code of tri and hexagrams (gua) of the Yi-jing and acknowledged its mythical creator, the ancestor emperor Fuxi, as the discoverer of binary arithmetic, and himself – as the one who found it again after four thousand years. At present, historical data do not allow us making an accurate conclusion about the dependence or independence of this outstanding discovery in Europe from the Chinese prototype. The time of the penetration of the initial information about the Yi-jing into Europe is still hidden by a veil of secrecy. The lack of a message about it in the book of Marco Polo is one of its mysteries. At the same time in the Mediterranean area traces of acquaintance with the Yi-jing studies are visible in such cultural phenomena as astrology and alchemy, Kabbalah and the teachings of Ramon Llull, sextine and hexachord. The beginning of the European study of the Yi-jing was laid by Jesuit missionaries who arrived in China at theend of the 16th century. Among them, by the end of the 17 th century, a whole trend of “Yi-jingists” or “figuralists” was formed. They saw Yi-jing as the Chinese Bible, embodying the original Divine Revelation in the form of the kabbalistic “figures” of the gua and being an expression of the common, sacred and antediluvian “hieroglyphic science” of the ancient world, that is, “Metaphysics of numbers, or general scientific method”, “containing all other knowledge”. Apparentlythe first information in Russia about the Yi-jing was published by the first Russiansinologist, German historian and philologist-polyglot G. (Th.) S. Bayer in the two-volume Museum Sinicum (Petersburg, 1730) in Latin. In Russian the primary in -formation about Yi-jing became available to the reader half a century later owing to the coryphaeus of Russian sinology of the 18th century Aleksei L. Leontiev. In 1782 he published an illustrated and commented translation of a fragment from Yi-jing (named Convenient Base) as an appendix to his translation of the Manchu text of the Statutes of the Great Qing (大清會典Dai-Qing hui-dian). Leontiev mentioned the French abbot who visited St. Petersburg in 1769 as the initiator of his appeal to the Yi-jing, but did not indicate his name. Petr E. Skachkov (1892–1964) agreed with Vsevolod S. Kolokolov (1896–1979) that this abbot was the famous French Jesuit missionary and versatile scientist Antoine Gaubil (1689–1759). However, he died ten years earlier. Most likely the interlocutor of Leontiev was a well-known theologian and economist-physiocrat, French abbot Nicolas Baudeau (1730–1792), who held confidential negotiations with Catherine IIin 1769 in St. Petersburg in connection with the situation in Poland. The secrecy of this mission on the eve of the first partition of Poland fully explains the concealment of his name in 1782 when he was still alive and preparing the second partition of Poland. Apparently, a look at the Yi-jing of the French enlighteners184 and physiocrats, expressed by F. Quesnay (1694–1774) and reported by Baudeauto Leontiev prompted him to link the ancient canon with Statutes of the Great Qing. Vasilii P. Vasiliev (1818–1900) expressed a number of original thoughts about the Yi-jing, which may have influenced the creation of his graphic system of Chinese characters and Mendeleev periodic table. Yulian K. Shchutsky (1897–1938), the first Russian researcher who specially studied the Yi-jing and wrote an extensive monograph about it, strangely ignored the statements of his domestic predecessors, but his innovative approach anticipated the neo-mystic Jungian tendency in Western interpretations of the Canon in the 20 th century. Due to the psychologization and aestheticization of the Yi-jing sanctified by world authorities in this field, after the Second World War this neo-mysticism penetrated the mass Western culture which repeated the initial success prepared by figuralists three centuries earlier on a new level and larger scale.
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김일수. "The Lifetime and National Independence Movement of Geo Yi Gyeong - hui (Jun 11, 1880 ~ Dec 4, 1949)." 한국학논집 ll, no. 63 (June 2016): 277–309. http://dx.doi.org/10.18399/actako.2016..63.009.
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Kim Dug Sam. "Modality and Iimplication of Chinese Minority Group's Cultural Change: Focused on Hui-zu's Culture and Yi-zu's Culture." Cross-Cultural Studies 29, no. ll (December 2012): 153–76. http://dx.doi.org/10.21049/ccs.2012.29..153.
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Cho, Sung-San. "Yi Hui-gyeong and Bak Je-ga’s Discourse on the Northern Learning and Ancient Learning in the Late Eighteenth Century." Korean History Education Review 130 (June 30, 2014): 83. http://dx.doi.org/10.18622/kher.2014.06.130.83.
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Furmanik-Kowalska, Magdalena. "Which tradition is mine? Chinese women artists and cultural identity." Journal of Contemporary Chinese Art 6, no. 2 (September 1, 2019): 305–19. http://dx.doi.org/10.1386/jcca_00009_1.
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Abstract References to native culture are frequently in the foreground of works by Chinese women artists. When they make contact with different cultures, although not necessarily connected with leaving their place of birth thanks to the transfer of information and cultural heritage that has developed extremely efficiently in the era of globalization (Gordon Mathews), they see their own entanglement in the cultural tradition. In the process of constructing their identity they try to find answers to the following question: which part of the cultural tradition is mine? Which one do I identify with? In the case of Chinese women artists, is it the legacy of literati? Classic ink painting and calligraphy? Or perhaps women's crafts that bear no name? Or perhaps a mixture of inspirations? Such questions about material heritage might also be augmented by others that consider aspects of the immaterial heritage of China. This article explores how Chinese women artists such as Chen Qingqing, Qin Yufen, Shi Hui, Wang Xiaohui, Cheng Caroline, Lin Tianmiao, Zhang Yanzi, Man Fung-yi, Liu Liyun, Peng Wei, Chen Lingyang, Chen Qiulin, Zhang Ou and Liu Ren refer to their cultural tradition.
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Lukš, Antonı́n, and Vlasta Peřinová. "Comment on “Equivalence between SWH phase operator and Ban's phase operator revealed by virtue of the |η〉 representation” by Hong-yi Fan and Hui Zou." Physics Letters A 265, no. 1-2 (January 2000): 156–58. http://dx.doi.org/10.1016/s0375-9601(99)00870-1.
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Naceur, Selmi, and Bel Hadj Salah Hedi. "Finite Element and Experimental Investigation of the Multipoint Flexible Hydroforming." Key Engineering Materials 554-557 (June 2013): 1290–97. http://dx.doi.org/10.4028/www.scientific.net/kem.554-557.1290.
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FINITE ELEMENT AND EXPERIMENTAL INVESTIGATIONS OF THE MULTI-POINT FLEXIBLE HYDOFORMING. N. Selmi*, H. BelHadjSalah* *Mechanical Engineering Laboratory (LGM), National Engineering School of Monastir (ENIM), University of Monastir, Avenue Ibn El Jazzar 5019, Monastir, Tunisia. naselmi2002@yahoo.fr, hedi.belhadjsalah@enim.rnu.tn. ABSTRACT Multi-point flexible forming (MPF) process is relatively recent flexible techniques [1], instead of the conventional fixed shape die sets, the basic idea in this process, consist to form the sheet metal between a pair of opposed matrices of punch elements, by adjusting the height of the punch elements [2]. Production of many parts with different geometry will be possible, just by using one same device and the need to design and manufacturing of various dies will be avoided that lead to great saving in time and manufacturing cost specially in the field of small batch or single production. The hydroforming process is attractive compared with conventional solid die forming processes, the basic idea consist to suppress one tool of two forming tools (punch or die), which is replaced by hydraulic pressure, only one tool is necessary to define the final shape of formed sheet. The multipoint flexible hydroforming, proposed in this paper, is an original process which combines the hydroforming and the multipoint flexible forming [3], to obtain a synergy of the advantages of both processes. The new process, subject of this work, is a combination of the last described processes that keep the whole flexibility of the basic multipoint flexible forming (with two dies), by using, only at one side, a single multipoint die to perform completely the final part shape, the fluid pressure is applied on the other side of the sheet metal part and substitutes advantageously the second die. Firstly, investigations were carried out by numerical simulation, to quantify, the effect of the most influent parameters on the process performances, and to highlight the ability of this new process, in the production of complex forms, as well as its contribution in quality, placed with regards existing flexible processes. Secondly, to prove the feasibility and to carry out a valuable experimental investigation of the multipoint flexible hydroforming, an experimental prototype was designed and realized, and successful doubly curved shell shape parts were obtained by the new process testing set up. The part profiles and the thickness distribution were in agreement with those obtained by numerical investigation furthermore, numerical investigation for efficient methods to suppress the dimpling phenomenon and edge buckling were confirmed by experimental investigation. From investigations it appears that the parameters attached to the discreet character of the multipoint tool, have an important effect on the quality of the final metal sheet product, such as, the punch elements density, the punch elements extremity curvature radius, the blank and the elastomeric interpolator thicknesses. From simulation results, it emerges essentially, that an adequate setting of parameters can upgrade the thickness distribution, reduce the residual stress and attenuate the dimples. References: [1] Zhong-Yi Cai, Shao-Hui Wanga, Ming-Zhe Li, (2008), Numerical investigation of multi-point forming process for sheet metal: wrinkling, dimpling and spring back, Int J Adv Manuf Technol (2008) 37:927–936. [2] Zhong-Yi Cai, Shao-Hui Wang, Xu-Dong Xu, Ming-Zhe Li (2009), Numerical simulation for the multi-point stretch forming process of sheet metal, journal of materials processing technology 209 (2009) 396–407. [3] N. Selmi, H. Bel hadj salah, Simulation numérique de l’hydroformage à matrice flexible, 7éme journées scientifiques en mécanique et matériaux JSTMM2010, Hammamet 26-27 novembre2010.
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Guo, Bing, Fei Yang, Junfu Fan, and Yuefeng Lu. "The Changes of Spatiotemporal Pattern of Rocky Desertification and Its Dominant Driving Factors in Typical Karst Mountainous Areas under the Background of Global Change." Remote Sensing 14, no. 10 (May 12, 2022): 2351. http://dx.doi.org/10.3390/rs14102351.
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There are significant differences in the dominant driving factors of rocky desertification evolution in different historical periods in southwest karst mountainous areas. However, previous studies were mostly conducted in specific periods. In this study, taking Bijie City as an example, the spatial and temporal evolution pattern of rocky desertification in Bijie City in the recent 35 years was analyzed by introducing the feature space model and the gravity center model, and then the dominant driving factors of rocky desertification in the study area in different historical periods were clarified based on GeoDetector. The results were as follows: (1) The point-to-point B (bare land index)-DI (dryness index) feature space model has high applicability for rocky desertification monitoring, and its inversion accuracy was 91.3%. (2) During the past 35 years, the rocky desertification in Bijie belonged to the moderate rocky desertification on the whole, and zones of intensive and severe rocky desertification were mainly distributed in the Weining Yi, Hui, and Miao Autonomous Region. (3) During 1985–2020, the rocky desertification in Bijie City showed an overall weakening trend (‘weakening–aggravating–weakening’). (4) From 1985 to 2020, the gravity center of rocky desertification in Bijie City moved westward, indicating that the aggravating degree of rocky desertification in the western region of the study area was higher than that in the eastern region. (5) The dominant factors affecting the evolution of rocky desertification in the past 35 years shifted from natural factor (vegetation coverage) to human activity factor (population density). The research results could provide decision supports for the prevention and control of rocky desertification in Bijie City and even the southwest karst mountainous area.
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Goldstein, Andrew, Lena Sophia Goldstein, Roberta Lipson, Sarah Bedell, Jue Wang, Sarah A. Stamper, Gal Brenner, et al. "Assessing the feasibility of a rapid, high-volume cervical cancer screening programme using HPV self-sampling and digital colposcopy in rural regions of Yunnan, China." BMJ Open 10, no. 3 (March 2020): e035153. http://dx.doi.org/10.1136/bmjopen-2019-035153.
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ObjectiveImplementation of a novel, rapid, high-volume, see-and-treat cervical cancer screening programme using self-swab human papillomavirus (HPV) testing and digital colposcopy in underserved regions of Yunnan China.Design480–980 women per day self-swabbed for high-risk HPV (hrHPV+). Four careHPV machines (Qiagen) were run simultaneously to test the specimens. All hrHPV+ patients were contacted the same day and digital colposcopy was performed with the enhanced visual assessment system (MobileODT). Digital images were obtained, and all suspected lesions were biopsied and then treated.SettingRural and underserved areas of the Yunnan province, Kunming municipality.Participants3600 women, mean age 50.2 years, who had never been screened for cervical cancer. The women were of the Yi, Hui, Dai and Han ethnicities.InterventionsCryotherapy was performed on all lesions suspicious for cervical intraepithelial neoplasia (CIN) 1 and loop electrosurgical excision procedure was performed on all lesions suspicious for ≥CIN2. Endocervical curettage was performed if the transformation zone was not fully visualised.Results216 women (6%) were hrHPV+. 168 underwent same-day colposcopy (23 CIN1, 17≥CIN2). Digital colposcopy was able to identify 15 of 16 (93.8%)≥CIN2 lesions.ConclusionsThis study illustrates a high-volume, rapid and practical strategy that can be used to screen and treat an ethnically diverse group of Chinese women. First, HPV self-sampling allows large numbers of women to be screened rapidly and relatively inexpensively. Only hrHPV+ women will then require further evaluation. Digital colposcopy is then performed on hrHPV+ women with a portable digital colposcope. The high-resolution images obtained can facilitate appropriate same-day treatment as they are able to accurately distinguish between CIN1 and ≥CIN2 lesions.
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BAOZHANG, T., Z. KAINING, K. JINXING, X. RUCHANG, L. MING, Z. CAIXIA, and T. LI. "Infection with human immunodeficiency virus and hepatitis viruses in Chinese drug addicts." Epidemiology and Infection 119, no. 3 (December 1997): 343–47. http://dx.doi.org/10.1017/s0950268897007784.
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The prevalence of antibody against hepatitis C virus (anti-HCV) and five hepatitis B virus markers (HBVM) was measured in 176 Chinese drug addicts, of whom 23 were AIDS patients. Of 176 drug addicts, 147 were members of ethnic minorities while 29 were Han, the majority ethnic group. The total prevalence rates of anti-HCV and HBVM were 35·8% and 50·6% respectively, significantly different (P<0·01). Anti-HCV and HBVM were together found in 22·7%. Similar prevalence rates were found among the different ethnic groups. Among the ethnic minorities, there was a significantly higher prevalence rate of anti-HCV in intravenous drug addicts (IVDA, 51·1%) than in oral drug addicts (20·3%). Furthermore, the prevalence of anti-HCV was significantly higher in needle-sharing abusers (60·4%) than in non-needle sharing ones (37·1%, P<0·05). The prevalence of HBVM was also significantly higher in needle-sharing abusers (69·8%) than in non-needle sharing ones (34·3%). Prevalence of HBsAg was significantly higher in drug abusers with AIDS (47·8%) than in IVDA only (16·1%). The anti-HCV positive rates among ethnic minority people were: for the Yi people 69·2%, the Hui 55·6%, the Bai 53·9%, the Dai 26·8% and the Wa 23·1%. No obvious difference was identified for HBVM. The prevalence rates of HCV, HBV and HCV+HBV in IVDA showed no significant difference (P>0·05) between the two regions. HIV, HCV and HBV infections may promote each other and be related to needle-sharing behaviour in drug abuse and to different subcultures and living habits.
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Chen, Qiu-Hong, Ri-Li Ge, Xiao-Zhen Wang, Hui-Xin Chen, Tian-Yi Wu, Toshio Kobayashi, and Kazuhiko Yoshimura. "Exercise performance of Tibetan and Han adolescents at altitudes of 3,417 and 4,300 m." Journal of Applied Physiology 83, no. 2 (August 1, 1997): 661–67. http://dx.doi.org/10.1152/jappl.1997.83.2.661.
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Chen, Qiu-Hong, Ri-Li Ge, Xiao-Zhen Wang, Hui-Xin Chen, Tian-Yi Wu, Toshio Kobayashi, and Kazuhiko Yoshimura. Exercise performance of Tibetan and Han adolescents at altitudes of 3,417 and 4,300 m. J. Appl. Physiol. 83(2): 661–667, 1997.—The difference was studied between O2 transport in lifelong Tibetan adolescents and in newcomer Han adolescents acclimatized to high altitude. We measured minute ventilation, maximal O2 uptake, maximal cardiac output, and arterial O2 saturation during maximal exercise, using the incremental exercise technique, at altitudes of 3,417 and 4,300 m. The groups were well matched for age, height, and nutritional status. The Tibetans had been living at the altitudes for a longer period than the Hans (14.5 ± 0.2 vs. 7.8 ± 0.8 yr at 3,417 m, P < 0.01; and 14.7 ± 0.3 vs. 5.3 ± 0.7 yr at 4,300 m, P < 0.01, respectively). At rest, Tibetans had significantly greater vital capacity and maximal voluntary ventilation than the Hans at both altitudes. At maximal exercise, Tibetans compared with Hans had higher maximal O2 uptake (42.2 ± 1.7 vs. 36.7 ± 1.2 ml ⋅ min−1 ⋅ kg−1at 3,417 m, P < 0.01; and 36.8 ± 1.9 vs. 30.0 ± 1.4 ml ⋅ min−1 ⋅ kg−1at 4,300 m, P < 0.01, respectively) and greater maximal cardiac output (12.8 ± 0.3 vs. 11.4 ± 0.2 l/min at 3,417 m, P < 0.01; 11.5 ± 0.5 vs. 10.0 ± 0.5 l/min at 4,300 m, P < 0.05, respectively). Although the differences in arterial O2saturation between Tibetans and Hans were not significant at rest and during mild exercise, the differences became greater with increases in exercise workload at both altitudes. We concluded that exposure to high altitude from birth to adolescence resulted in an efficient O2 transport and a greater aerobic exercise performance that may reflect a successful adaptation to life at high altitude.
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Koo, Hui Min, Xiang-Ling Hou, Yu-Lin Li, Yi-Wen Lu, Viriya Adhiguna Winarso, Yu-Cheng Weng, and Wei-Ting Chao. "Abstract 1001: Investigates the role of vesicle trafficking in E-cadherin dynamics in collective migrated colon cancer cells." Cancer Research 82, no. 12_Supplement (June 15, 2022): 1001. http://dx.doi.org/10.1158/1538-7445.am2022-1001.
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Abstract Cell adherens junction plays an important role in cell communication and regulation. E-cadherin is an important protein as adherens junctions. Loss of E-cadherin leads to epithelial cells transit to mesenchymal cells. Studies has demonstrated that E-cadherin dominates cell contact inhibition, which plays an important role in cell growth, however, recent studies demonstrated collective cell migration required E-cadherin expression escaping cell growth inhibition is important in metastasis. E-cadherin dynamics has been shown to be regulated by vesicle trafficking, however, the detail mechanism of vesicle trafficking in collective cell migration is not clear. This study is investigating the relationship between the endocytosis mechanism of E-cadherin and its dynamic expression resulting in collective cell migration. The expression of E-cadherin was controlled by regulating the concentration of calcium and EDTA to observe its effect on cell-cell contact. Through Transmission electron microscope, immunofluorescence staining and western blotting to observe the relationship between vesicle trafficking and E-cadherin. Collective cell migration is analyzed by transwell assay. When calcium concentration was increased, the E-cadherin in cell-cell contacts became stronger. Conversely, when EDTA concentration was increased, the E-cadherin in the cell-cell contacts became weaker. Meanwhile, we found colocalization occurs in Rab5 and Rab11 with E-cadherin. Besides, intracellular E-cadherin transported to the lysosome for degradation was also observed. We identified the role of E-cadherin is regulated in endocytosis mechanism and at cell-cell contacts through different regulatory, which provides a basis for the future use of drugs to affect E-cadherin expression to inhibit collective cell migration. Citation Format: Hui Min Koo, Xiang-Ling Hou, Yu-Lin Li, Yi-Wen Lu, Viriya Adhiguna Winarso, Yu-Cheng Weng, Wei-Ting Chao. Investigates the role of vesicle trafficking in E-cadherin dynamics in collective migrated colon cancer cells [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 1001.
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Demiańczuk, Andrzej. "Ruch Nowego Życia w Chinach, 1934–1948." Studia nad Autorytaryzmem i Totalitaryzmem 43, no. 3 (December 20, 2021): 515–25. http://dx.doi.org/10.19195/2300-7249.43.3.32.
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In recent decades, there was a notable surge of interest in the history of the Republic of China (1912–1949). New Life Movement (Xin shenghuo yundong) was one of the most important en-deavours undertaken during the so-called Nanjing Decade (1927–1937) — a period of authoritarian rule of Guomindang (National Party), after the triumph of the Northern Expedition and before the outbreak of the Second Sino-Japanese War. Inaugurated in 1934, this movement sought to revive Confucian virtues and create better society through the promotion of proper behaviour (especially etiquette and hygiene). Virtues, whose realisation in daily life was stated as the goal of the Move-ment, were li — propriety, yi — right action, lian — integrity, and chi — a sense of shame. Later, these goals were expanded to include promotion of militarisation (junshihua), aesthetic uplifting (yishuhua), and improving the production (shengchanhua) in peopleʼs lifestyles. Although the New Life Movement was initiated by Chiang Kai-shek on 19 February 1934 in Nanchang, in many respects it was a continuation of previous policies. To realise the New Life Movement, the Society for the Promotion of the New Life Movement (Xin shenghuo yundong cujin hui) was founded in 1934. Members of different factions in Guomindang participated in its activities. After the first two years, the New Life Movement disappeared from the spotlight, but remained active at least until 1948. During the war, the main task of the movement was participation in war efforts and, after the conflict ended, in post-war recovery. In the end, the New Life Movement failed in realisation of its stated goals. Nevertheless, it seems that its activities were still beneficial for Guomindang’s government. This article presents an outline of history and origins of the New Life Movement, as well as describe its goals and methods. In the end, there will be an evaluation of this important and controversial movement and its place in the history of Guomindang and China.
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Shao, Zhi-Ming, Zhong-Hua Wang, Yi-Zhou Jiang, Yin Liu, Xiu-Zhi Zhu, Yi Xiao, Song-Yang Wu, et al. "Abstract OT3-27-01: Subtyping-based platform guides precision medicine for heavily pretreated metastatic triple-negative breast cancer: a multicenter, phase 2, umbrella, FUTURE trial." Cancer Research 83, no. 5_Supplement (March 1, 2023): OT3–27–01—OT3–27–01. http://dx.doi.org/10.1158/1538-7445.sabcs22-ot3-27-01.
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Abstract Background: Triple-negative breast cancer (TNBC) is a heterogeneous disease and lacks effective treatment. Our previous study classified TNBCs into four subtypes (luminal androgen receptor [LAR], immunomodulatory [IM], basal-like immune-suppressed [BLIS], mesenchymal-like [MES]) with distinct molecular features. We aimed to assess the efficacy and safety of molecular subtype-derived precision treatment in patients with heavily pretreated metastatic TNBC. Methods: This open-label, phase 2, umbrella trial included patients from four centers in China. Participants were women (aged ≥18 years) with histologically confirmed metastatic TNBC with disease progression after multiple lines of standard chemotherapy. Patients were enrolled into seven parallel arms according to their molecular subtypes: LAR with or without ERBB2 somatic mutation/amplification assigned to arm A (pyrotinib with capecitabine) and arm B (androgen inhibitor included therapy); IM assigned to arm C (anti-PD-1 antibody with nab-paclitaxel); BLIS with or without BRCA1/2 germline mutation assigned to arms D (PARP inhibitor included therapy) and E (anti-VEGFR included therapy); MES without or with PI3K-AKT mutation assigned to arms F (anti-VEGFR included therapy) and G (everolimus with nab-paclitaxel). Bayesian predictive probability was adopted to monitor each arm, which can be terminated independently according to a prespecified futility or efficacy boundary. This trial is registered with ClinicalTrials.gov, NCT03805399. Findings: Between October 18, 2018, and February 11, 2022, we enrolled 141 patients. All patients were heavily pretreated and resistant to six categories of the most common chemotherapeutic agents used in breast cancer treatment, with a median of 3 previous lines of therapies in the metastatic setting (Table 1 and 2). The median follow-up was 18.3 months (IQR 11.7-27.7). A confirmed objective response was achieved in 42 (29.8%, 95% CI 22.4-38.1) of the 141 patients. The median PFS was 3.4 months (95% CI 2.7-4.2), and the median OS was 10.7 months (95% CI 9.0-12.3) (Table 3). Arms A, C, E and G achieved efficacy boundaries, with 3 (75.0%) out of 4 patients in arm A, 20 (43.5%) out of 46 patients in arm C, 13 (28.3%) out of 46 patients in arm E, and 3 (33.3%) out of 9 patients in arm G achieving objective responses. Potential predictive biomarkers of efficacy in each arm were explored. Safety data were consistent with the known safety profiles of relevant drugs. Interpretation: We demonstrate the feasibility and clinical utility of a subtyping-based, genomic sequencing-guided strategy which allows the majority of heavily pretreated metastatic TNBCs to benefit from precision treatment. Most arms exhibit promising efficacy and manageable toxicities, providing subtyping schema to optimize personalized treatment. Table 1. The FUTURE trial schema. Patients are stratified into seven arms using the FUSCC 484-gene NGS panel testing and IHC subtyping. Abbreviations: mTNBC, metastatic triple-negative breast cancer; NGS, next-generation sequencing; IHC, immunohistochemistry; FUSCC, Fudan University Shanghai Cancer Center; LAR, luminal androgen receptor; IM, immunomodulatory; BLIS, basal-like immune-suppressed; MES, mesenchymal-like; n, number; AR, androgen receptor; PD-1, programmed cell death-1; PARPi, poly ADP-ribose polymerase inhibitor; VEGF, vascular endothelial growth factor; mTORi, mammalian target of rapamycin inhibitors. Table 2. Patient characteristics in the FUTURE trial. Table 3. Summary of treatment efficacy of TNBC in the FUTURE trial Citation Format: Zhi-Ming Shao, Zhong-Hua Wang, Yi-Zhou Jiang, Yin Liu, Xiu-Zhi Zhu, Yi Xiao, Song-Yang Wu, Wen-Jia Zuo, Qiang Yu, A-Yong Cao, Jun-Jie Li, Ke-Da Yu, Guang-Yu Liu, Jiong Wu, Tao Sun, Jiuwei Cui, Zheng Lv, Hui-Ping Li, Xiao-Yu Zhu. Subtyping-based platform guides precision medicine for heavily pretreated metastatic triple-negative breast cancer: a multicenter, phase 2, umbrella, FUTURE trial [abstract]. In: Proceedings of the 2022 San Antonio Breast Cancer Symposium; 2022 Dec 6-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2023;83(5 Suppl):Abstract nr OT3-27-01.
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Winarso, Viriya Adhiguna, Yi-Wen Lu, Yu-Cheng Weng, Xiang-Ling Hou, Hui Min Koo, Yu-n. Li, and Wei-Ting Chao. "Abstract 1578: Interaction of E-cadherin and EGFR in the collective cell migration of colon cancer cells." Cancer Research 82, no. 12_Supplement (June 15, 2022): 1578. http://dx.doi.org/10.1158/1538-7445.am2022-1578.
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Abstract Collective cell migration is one of the most important cellular events where a cluster of cells moves together in a coordinated way. Many studies have found this phenomenon as the hallmark of cancer progression and metastasis. In epithelial single cell migration, downregulation of adherens junction (AJ) molecule E-cadherin occurs at the initial step known as the Epithelial to Mesenchymal Transition (EMT). However, in collective cell migration, E-cadherin junction is maintained to provide adhesion between cells. Moreover, it also mediates the cell-cell intercommunication that is critical, for instance, to alter the group polarization through actin cytoskeleton remodeling. Interestingly, Epidermal Growth Factor Receptor (EGFR) was found to colocalize with E-cadherin in the cell-cell contact region, implicating that E-cadherin and EGFR might interact in the cell junction of collective cell migration. To address this, a human colorectal cancer cell line exhibiting epithelial phenotype HT-29 was used. The cell density and calcium presence were modified to infer the effect of differential expression and stability of E-cadherin on the cellular signaling of proliferation and migration. The results showed that stable and enhanced expression of E-cadherin downregulates EGFR expression and reduces its activity. Moreover, the Src phosphorylation increased when the cell-cell contact was strengthened via calcium addition and decreased when the cell-cell contact was diminished via calcium chelation. Overall, this indicates that E-cadherin expression at the cell-cell junction and contact stability determine the EGFR expression, activity, and Src phosphorylation. With the goal of deciphering the relationship of E-cadherin and EGFR in cell contact, proliferation, and migration, we intend to finally implement the knowledge as a strategy or approach in promoting alternative methods to inhibit metastasis. Citation Format: Viriya Adhiguna Winarso, Yi-Wen Lu, Yu-Cheng Weng, Xiang-Ling Hou, Hui Min Koo, Yu-n Li, Wei-Ting Chao. Interaction of E-cadherin and EGFR in the collective cell migration of colon cancer cells [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 1578.
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Li, Yu-Lin, Yu-Cheng Weng, Viriya Adhiguna Winarso, Yi-Wen Lu, Hui Min Koo, Xiang-Ling Hou, Kai-Yu Tseng, and Wei-Ting Chao. "Abstract 2263: The role of E-Cadherin mediated cell division in promoting collective colon cancer cell migration." Cancer Research 82, no. 12_Supplement (June 15, 2022): 2263. http://dx.doi.org/10.1158/1538-7445.am2022-2263.
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Abstract Collective cell migration is the cell cohort migrates toward the direction. Other than single cell migration, collective cell migration requires cell-cell connection with E-cadherin, however, E-cadherin is the epithelial marker in epithelial mesenchymal transition and acts as tumor suppressor function. Therefore, the role of E-cadherin in collective cell migration is still under investigated. In the collected cells, cell migration and cell division are coordinated for the cohort motility, the mechanism is still not clear. This study is to investigate the role of E-cadherin orientation in cell division dependent collective cell migration. Colorectal cancer cell line HT29 with epithelial morphology were used and treated with Cetuximab and Dasatinib to inhibit EGFR and Src activity. Cells were also incubated on fibronectin to monitor the matrix dependent environment. The polarity of E-cadherin distribution and cell contact inhibition were defined and detected by Immunofluorescence. The molecular expression of p-FAK, CDK4, and cell proliferation marker, Ki67 were revealed by Immunofluorescence confocal microscopy and Western blot. The collective cell migration is analyzed and compared by wound healing and transwell assay. In the results, the polarized distribution of E-cadherin in leading cells which revealed pFAK expression on the cell membrane was associated with Ki67 and CDK4 positive proliferated cells. When cells were grown on fibronectin, the proliferated cells in the leading were decreased. When cells were treated with cetuximab, the E-cadherin distribution were not changed and had fewer effect on cell migration. However, dasatinib treatment can modulate E-cadherin orientation and suppress cell proliferation and cell migration. These results suggested modulate E-cadherin orientation such as Src inhibition can be the potential treatment strategy in colon cancer Citation Format: Yu-Lin Li, Yu-Cheng Weng, Viriya Adhiguna Winarso, Yi-Wen Lu, Hui Min Koo, Xiang-Ling Hou, Kai-Yu Tseng, Wei-Ting Chao. The role of E-Cadherin mediated cell division in promoting collective colon cancer cell migration [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 2263.
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Hou, Xiang-Ling, Hui Min Koo, Yu-Cheng Weng, Yi-Wen Lu, Viriya Adhiguna Winarso, Yu-Lin Li, and Wei-Ting Chao. "Abstract 1582: Chloroquine inhibites Rab11 mediated E-cadherin transport in collective colon cancer cell migration." Cancer Research 82, no. 12_Supplement (June 15, 2022): 1582. http://dx.doi.org/10.1158/1538-7445.am2022-1582.
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Abstract Cell migration is regulated by multiple molecular pathways to change the morphology from epithelial to mesenchymal type and is important in cancer metastasis. In has been demonstrated epithelial mesenchymal transition (EMT) is related to E-cadherin expression level. The loss of E-cadherin expression results in tumor proliferation and metastasis. Recently, studies have been demonstrated the collective cancer cell migration which expresses high E-cadherin is a powerful mechanism of metastasis. Therefore, the role of E-cadherin in cancer metastasis is still not clear. Clathrin-mediated endocytosis (CME) was shown to regulate E-cadherin turnover on the membrane and the function of lysosome is also associated with cell vesicle trafficking, however, the role of lysosome in collective cell migration is not known. This study is investigating the role of lysosome in regulating E-cadherin dynamics through vesicle trafficking in collective colon cell migration. In the experiment, we used colon cancer cells with epithelial morphology and observed the relation of E-cadherin with endocytic protein clathrin, Rab5 and the recycling protein Rab11 in collective migrated cells. In the result, inhibition of lysosome activity by chloroquine treatment has great suppression effect on anchorage independent cell growth and inhibited collective cell migration. We observed that nocodazole treatment inhibited clathrin-mediated endocytosis, which caused E-cadherin to accumulate on the cell membrane. Western blot and confocal microscopy demonstrated chloroquine treatment induced Rab11 expression and accumulated in the cytosol which affected E-cadherin turnover. Our results demonstrated inhibits lysosome activity can suppress colon cancer cell growth and collective migration through lysosome mediated E-cadherin translocation. Chloroquine may be the potential treatment for colon cancer therapy. keywords: colon cancer, collective cell migration, E-cadherin, vesicle trafficking, lysosome Citation Format: Xiang-Ling Hou, Hui Min Koo, Yu-Cheng Weng, Yi-Wen Lu, Viriya Adhiguna Winarso, Yu-Lin Li, Wei-Ting Chao. Chloroquine inhibites Rab11 mediated E-cadherin transport in collective colon cancer cell migration [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 1582.
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Leng, Shao-Chuan. "Gu Weijuin Hui Yi Lu (Memoirs of V. K. Wellington Koo), Vol. I. Translated by the Institute of Modern History, Chinese Academy of Social Sciences, People's Republic of China, from the original English Oral History microfilm text. [Beijing: Zhung Hua Shu Ju, 1983. 442 pp. Renminbi 2.45.]." China Quarterly 105 (March 1986): 147–49. http://dx.doi.org/10.1017/s0305741000036845.
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Yijiang, Zhou, Yin Ruixing, Li Yiyang, Deng Yaju, Pan Shangling, Lin Weixiong, and Yang Dezhai. "Association of TaqIB Polymorphism in the Cholesteryl Ester Transfer Protein Gene With Serum Lipid Levels in the Guangxi Hei Yi Zhuang and Han Populations." Journal of Investigative Medicine 56, no. 6 (August 1, 2008): 847–57. http://dx.doi.org/10.2310/jim.0b013e3181820832.
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BackgroundCholesteryl ester transfer protein (CETP) plays an important role in lipoprotein metabolism. The present study was undertaken to compare the difference in the CETP TaqIB gene polymorphism and its association with serum lipid levels between the Guangxi Hei Yi Zhuang and Han populations.MethodsA total of 758 subjects of Hei Yi Zhuang and 778 participants of Han Chinese were surveyed. Genotyping of the CETP TaqIB was performed using polymerase chain reaction and restriction fragment length polymorphism and then confirmed using direct sequencing.ResultsThe genotypic and allelic frequencies were significant differences between smokers and nonsmokers, or between hypertensives and normotensives in Hei Yi Zhuang, and between drinkers and nondrinkers in Han. The levels of high-density lipoprotein cholesterol (HDL-C) and apolipoprotein AI in Hei Yi Zhuang but not in Han were higher in B2B2 genotype than in B1B1 genotype (P < 0.01 for each). Higher HDL-C levels in Hei Yi Zhuang were found only in females, nondrinkers, nonsmokers, subjects with a body mass index of 24 kg/m2 or lesser, or normotensives in B2B2 genotype. Higher HDL-C levels in Han were found only in females in B2B2 genotype and in subjects with a body mass index of 24 kg/m2 or lesser or normotensives in B1B2 genotype. The levels of HDL-C in B1B1 and B1B2 individuals in both ethnic groups were higher in drinkers than in nondrinkers.ConclusionsThere were significant differences in the interactions between the CETP TaqIB genotypes and several environmental factors in the Hei Yi Zhuang and Han populations. The polymorphism predicted differences in HDL-C and ApoAI in the Hei Yi Zhuang but not in the Han Chinese, even after adjustment for confounding variables. This means that the gene may not be truly involved in regulation of high-density lipoprotein metabolism or that there is an ethnic-specific effect.
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Weng, Yu-Cheng, Yu-Lin Li, Xiang-Ling Hou, Hui Min Koo, Yi-Wen Lu, Viriya Adhiguna Winarso, Chia-Wen Lin, and Wei-Ting Chao. "Abstract 1626: The orthotopic mouse study of cetuximab and dasatinib treatment on BRAF mutated colon cancer cells." Cancer Research 82, no. 12_Supplement (June 15, 2022): 1626. http://dx.doi.org/10.1158/1538-7445.am2022-1626.
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Abstract Colorectal cancer is one of the most common cancer in the world. The mortality rate is the third among the top ten cancers. Among colorectal cancer patients, about 65-75% of patients have overexpression of epithelial growth factor receptors (EGFR). The antibody drug cetuximab that inhibits EGFR has also been developed. Moreover, overexpression of src protein is found in about 80% of patients with colorectal cancer. Higher levels of Src expression is related to the metastasis of colon cancer. Dasatinib is an oral taken tyrosine kinase inhibitor to inhibit the src phosphorylation. Therefore, in this study, the mechanism of cetuximab and dasatinib combined treatment in the orthotopic mouse model is investigated. The in vivo mechanism of EGFR and E-cadherin crosstalk in the mouse model is discussed. In this study, HT-29 colon cancer cells with BRAF V600E mutation were orthotopically injected into the cecum wall of BALB/c nude male mice. Two weeks later, cetuximab, dasatinib, and combined treatment of cetuximab and dasatinib were applied for three weeks. The tumor sizes were then recorded after sacrificed. Tumor Tissue were processed for tissue section with H&E staining. Immunohistochemistry (IHC) was applied to detect EGFR, p-Src, E-cadherin with specific antibodies. The protein expression levels were achieved by Western blot. In the results, the tumor size was smaller in cetuximab and dasatinib combined treated group. In IHC staining, the E-cadherin expression were not apparent in primary tumor site, however, were abundant in migrated cells. P-src expression was reduced in the dasatinib treated group and combined treatment group. In western blot result, the E-cadherin was increased after the treatment of dasatinib, and the p-src expression was inhibited after dasatinib treatment and combined treatment. Our results demonstrated cetuximab combined with dasatinib has the better result of suppression of BRAF mutated colon cancer cell growth and metastasis in the orthotopic mouse model. Citation Format: Yu-Cheng Weng, Yu-Lin Li, Xiang-Ling Hou, Hui Min Koo, Yi-Wen Lu, Viriya Adhiguna Winarso, Chia-Wen Lin, Wei-Ting Chao. The orthotopic mouse study of cetuximab and dasatinib treatment on BRAF mutated colon cancer cells [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 1626.
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Han (韓東育), Dongyu. "The Rise and Fall of the Hua-Yi System in East Asia." Journal of Chinese Humanities 5, no. 2 (July 6, 2020): 200–214. http://dx.doi.org/10.1163/23521341-12340080.
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Abstract The Hua-Yi 華夷 system that spread in East Asia in the form of tribute relationships during the Ming dynasty [1368-1644] began as a system based on China’s perceived cultural superiority, but slowly evolved into a system centered on nationalism. Accordingly, the kinship networks embedded in the Hua-Yi system were also continually evolving, breaking down, and reforming in a cycle that repeated itself multiple times. Amid this process, ethnocentrism [zi minzu zhongxin zhuyi 自民族中心主義] and “interest centralism” [liyi zhongxin zhuyi 利益中心主義] played key roles in the formation and eventual dissolution of the Hua-Yi system.
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Lin, Hui-Yi, L. Joseph Su, Lora J. Rogers, Gail A. Runnells, Ping-Ching Hsu, Shelbie D. Stahr, and Tung-Chin Chiang. "Abstract 1450: Interactions of DNMTs genetic variants associated with breast cancer risk." Cancer Research 82, no. 12_Supplement (June 15, 2022): 1450. http://dx.doi.org/10.1158/1538-7445.am2022-1450.
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Abstract Background: DNA methyltransferases (DNMTs) control DNA methylation and impact gene expression. Many studies have demonstrated that genetic variants in DNMT genes play a role in cancer development, including breast cancer. However, the impact of SNP-SNP interactions for DNMTs associated with breast cancer risk is unclear. The objective is to evaluate SNP-SNP interactions associated with breast cancer risk. Methods: We selected 14 SNPs in 3 DNMT genes (DNMT1, DNMT3A, and DNMT3B) for the 4,195 women (1:2 match for breast cancer cases and controls), including 1,085 African Americans (AAs) and 3,110 European Americans (EAs) in the Arkansas Rural Community Health (ARCH) cohort. We included different inheritance models (dominant, recessive, and additive) for individual SNP effects, using logistic regressions with breast cancer status (yes/no) as the outcome. Two-way SNP-SNP interactions associated with breast cancer risk were analyzed using the SNP Interaction Pattern Identifier (SIPI) approach developed by our research team. Results: Out of the 14 DNMTs SNPs, we found two SNPs (rs7605753 and rs10196635 in DNMT3A) were individually associated with breast cancer risk (p<0.05) in EAs, however, none was statistically significant in AAs. Interestingly, we applied the SIPI approach, targeting SNP-SNP interactions,19 SNP-SNP interaction pairs for EAs, and 6 pairs for AAs associated with breast cancer risk. These promising SNP interaction pairs had an interaction p-value less than 0.05, far less than the p-values of the 2 constituent SNPs. Also, these promising SNP-SNP interaction pairs are different between races. For example, the EA women with the CC + AT/TT genotype in rs12991495 + rs10196635 (both in DNMT3A) had a higher risk of breast cancer risk than other genotype combinations (Odds ratio [OR]=2.2, p=0.011). On the other hand, the AA women with the TT+AA genotype in the SNP pair of rs2304429 (DNMT3A) + rs2290684 (DNMT1) tend to have a higher breast cancer risk than other genotype combinations in the same pair (OR=4.3, p=0.034). Notably, the individual effects of the two constituent SNPs are not significant (p=0.537 and 0.547). Conclusion: Our findings support that the SNPs in DNMT genes play an essential role in breast cancer risk. SIPI is an excellent tool to evaluate SNP-SNP interactions, which can better predict breast cancer risk. Citation Format: Hui-Yi Lin, L. Joseph Su, Lora J. Rogers, Gail A. Runnells, Ping-Ching Hsu, Shelbie D. Stahr, Tung-Chin Chiang. Interactions of DNMTs genetic variants associated with breast cancer risk [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 1450.
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Lassak, Adam J., Monika Rak, Melody C. Baddoo, Hui-Yi Lin, and Krzysztof Reiss. "Abstract 3170: Human retroviral sequences transcription in glioma/glioblastoma sample." Cancer Research 82, no. 12_Supplement (June 15, 2022): 3170. http://dx.doi.org/10.1158/1538-7445.am2022-3170.
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Abstract In glioblastoma patients, expansion of glioma initiating cells (GICs), a discrete population of cells demonstrating stem-like phenotype, is often associated with drug resistance development and ultimately cancer recurrence. Therefore a better understanding of the molecular and cellular mechanisms underlying the origin of GICs is critical to develop new therapies better targeting glioblastoma. Human endogenous retroviral sequences (HERVs), present in approximately 500,000 copies and comprising nearly 8% of the human genome, may serve as an abundant genetic material equipping GIC with phenotypic plasticity needed to develop stem-like phenotype. Recent epigenomic and transcriptomic data show HERV activation during early human development. Moreover, increased HERV transcription is observed in OCT4/SOX2/KLF4/c-MYC induced pluripotent cells. Finally, activation of HERV loci transcription is also commonly observed in different tumor types. Using publicly available The Cancer Genome Atlas Glioblastoma Multiforme (TCGA-GBM) RNA-seq data collection, we have quantified transcripts for all 13,208 HERV loci annotated in the RepBase database. To improve the accuracy of quantifying the HERV transcriptomic landscape, we reassigned already mapped fragments to the most probable transcript using the Telescope software. Our comprehensive approach allowed us to identify the set of HERV loci uniquely dysregulated in the glioblastoma compared to normal brain tissue. In addition, we compared 540 low-grade glial tumors from TCGA-LGG project (classified as grade II and III gliomas) with 165 glioblastoma samples from TCGA-GBM (classified as grade IV gliomas) using the same bioinformatics pipeline. Comprehensive analysis of transcript levels allowed us to identify HERV assemblage differentially expressed between these two patient cohorts. The correlation between HERV and ORF transcript levels show strong coregulation of HERVs expression with genes involved in establishing/maintaining embryonic/neural/glial stem cells phenotype. To confirm our observations we have up- or downregulated HERV loci combining guide RNA array targeting robustly approximately 90% of HERV LTR5Hs elements with a vector expressing CRISPR-based transcriptional activator or repressor. Downregulation of HERV transcription with this system was associated with the inhibition of clonogenic growth in cell culture. In summary, this study sets the stage for identifying HERV loci that could serve as potential GIC biomarkers, as well as the molecular targets for GIC elimination. Citation Format: Adam J. Lassak, Monika Rak, Melody C. Baddoo, Hui-Yi Lin, Krzysztof Reiss. Human retroviral sequences transcription in glioma/glioblastoma sample [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 3170.
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Lin, Jiun-Nong, Chung-Hsu Lai, Chih-Hui Yang, and Yi-Han Huang. "Correction: Jiun-Nong Lin; Chung-Hsu Lai; Chih-Hui Yang and Yi-Han Huang. Comparison of Clinical Manifestations, Antimicrobial Susceptibility Patterns, and Mutations of Fluoroquinolone Target Genes between Elizabethkingia meningoseptica and Elizabethkingia anophelis Isolated in Taiwan. Journal of Clinical Medicine 2018, 7, 538." Journal of Clinical Medicine 8, no. 4 (April 22, 2019): 546. http://dx.doi.org/10.3390/jcm8040546.
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Fan, Liang-Shih. "In honor of Professor Yi Hua Ma." Journal of the Taiwan Institute of Chemical Engineers 40, no. 3 (May 2009): 237. http://dx.doi.org/10.1016/j.jtice.2009.01.005.
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Kim cheol-woon. "Chunqiu period’s ‘Zun-wang-yang-yi-lun’ and ‘Hua Yi Fen Bie Lun’." Journal of East Aisan Cultures ll, no. 62 (August 2015): 253–78. http://dx.doi.org/10.16959/jeachy..62.201508.253.
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Xie, Hui, Wei Li, Yufeng Yao, Sujie Ni, Tongbo Yi, Jinling Cheng, Qi Fang, et al. "Abstract P2-13-41: First-line pyrotinib plus trastuzumab and nab-paclitaxel for patients with HER2-positive advanced breast cancer." Cancer Research 82, no. 4_Supplement (February 15, 2022): P2–13–41—P2–13–41. http://dx.doi.org/10.1158/1538-7445.sabcs21-p2-13-41.
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Abstract Background: Overexpression of human epidermal factor receptor 2 (HER2) is seen in 15-20% of breast cancer and results in more aggressive clinical behavior and poor prognosis. This study (ChiCTR2000030618) analyzed the efficacy and safety of pyrotinib plus trastuzumab and nab-paclitaxel in patients with previously untreated HER2-positive locally recurrent or metastatic breast cancer.Methods: Patients with previously untreated HER2-positive locally recurrent or metastatic breast cancer received pyrotinib (400 mg, qd), trastuzumab (H, 8 mg/kg loading dose, followed by 6 mg/kg every 3 weeks) and nab-paclitaxel (260 mg/m² every 3 weeks) until disease progression or an unacceptable adverse event (AE). The primary endpoint was progression-free survival (PFS). Secondary endpoints included objective response rate (ORR), disease control rate (DCR), overall survival (OS), and AEs.Results: A total of 28 patients (median age: 55.5 years [28-78]) were enrolled from April 2020 to June 2021. All 28 patients (100%) had Eastern Cooperative Oncology Group performance status of 1. The metastatic sites were in brain (14.29%), liver (25.00%), bone (28.57%) and lung (53.57%). HR+ and HR- for primary tumor accounted for 57.14% and 42.86%, respectively. Trastuzumab was previously administered in the (neo)adjuvant setting to 17(60.71%) patients. Eight patients with measurable lesions were evaluable for response. 5 (62.50%) patients had partial response (PR) and 3 (37.50%) patients achieved stable disease (SD), resulting in an ORR of 62.50% and DCR of 100.00%. Median PFS has not yet been reached. Twenty-one patients were included in the safety assessments. The most common AE was diarrhea (85.71%), but only 3 (14.29%) patients reported Grade ≥ 3 diarrhea which could be well controlled. The median onset of diarrhea was 1.5 days after start of treatment and the median duration was 9 days. Most diarrhea events were reported during the first cycle of treatment and the frequency persistently declined in the following cycles. Moreover, the AEs of all grades that were documented in ≥20% of patients included leukopenia (28.57%), anemia (23.81%), thrombocytopenia (19.05%), γ-glutamyltransferase increased (19.05%), vomiting (19.05%), rash (19.05%) and alanine aminotransferase increased (19.05%). No treatment-related deaths were reported.Conclusion: Pyrotinib plus trastuzumab and nab-paclitaxel showed promising efficacy in first-line HER2-positive breast cancer and were well tolerated. More data would be analyzed and reported in the future. Citation Format: Hui Xie, Wei Li, Yufeng Yao, Sujie Ni, Tongbo Yi, Jinling Cheng, Qi Fang, Lei Zhang, Jun Zhou, Xiaohong Wu, Chunbin Wang, Yanan Zhang, Jianwei Qin, Qing Shao, Tao Zhao, Xiaohong Huang, Lingyun Xu. First-line pyrotinib plus trastuzumab and nab-paclitaxel for patients with HER2-positive advanced breast cancer [abstract]. In: Proceedings of the 2021 San Antonio Breast Cancer Symposium; 2021 Dec 7-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2022;82(4 Suppl):Abstract nr P2-13-41.
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Nataliia, Sun. "The genesis of Taiwanese piano art: historical and cultural context." Problems of Interaction Between Arts, Pedagogy and the Theory and Practice of Education 63, no. 63 (January 23, 2023): 52–74. http://dx.doi.org/10.34064/khnum1-63.03.
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Introduction. The article examines the origins of Taiwanese piano art, its evolution, the influence of national and numerous non-national musical traditions. Until today, no special study devoted to the general panorama of these important processes has been created. The general picture of the formation and development of Taiwanese musical culture in the context of the political, economic and social situation is considered. The purpose of the article is to highlight the origins of Taiwanese piano art, which influenced its evolution, the process of introducing national and numerous non-national elements at the main stages of its formation and development. With the help of analytical, historical, comparative, interdisciplinary methods of research, a number of tasks are solved: the role of Western Christian missionaries in the development of musical education and piano art on the island is determined, the reasons why the Western classical music was accepted by the local society, the questions about the founders of the system of Western of classical music education, the programs and forms of learning in the first music schools in Taiwan, the names of the first Taiwanese composers-pianists are clarified; а periodization of the development of piano art in Taiwan is proposed. Results. The most important historical stages of the formation and development of Taiwanese piano art can be considered: – the period of its creation from the end of the 16th century to 1894; – the period of Japanese colonial rule from 1895 to 1945; – the period of development of national self-awareness, 1946–1986; – the period of reunification with mainland China from 1987. The proposed periodization makes it possible to reveal the entire historical and cultural context of the existence of piano art in Taiwan, to project its genetic settings for further stages of its development. Its basis was national folklore, but since the middle of the 16th century, the island was visited by Spanish, Portuguese, Dutch and Canadian colonists, and the first contacts of Western music with the indigenous population of Taiwan were made thanks to the activities of Western missionaries and were subordinated mainly to religious purposes. The stage of Japanese colonial rule was important for the development of piano art on the island. Due to the influence of Japan, Taiwanese musicians had further opportunities to join the system of Western classical music education, as the Japanese government was helping Taiwanese youth to obtain it. After 1920, Western classical music becomes popular in Taiwan; the formation of composer creativity in the field of piano music also takes place – the activities of such Taiwanese composers and pianists as Chiang Wen-Yeh, Chen Sizhi, Kuo Chih-Yuan, Kao Tzu-Mei and others. In the years 1946–1986, we observe the further development of performing and teaching activities at the island, a bright burst of creativity by such composers as Chang-Hui Hsu, Hsiao Tyzen, Shui-Long Ma and others. After 1987, active musical contacts between China and Taiwan contribute to the further progress of the island’s piano art. The piano works of Taiwanese composers Shih-Hui Chen, Fan-Ling Su, Chien-Yu Huang and others are widely popularized. In recent decades, the performing activities of Taiwanese pianists, represented in the international space by the names of Chien-Yu Huang, Yi Chih Lu, Chiu Tze Lin and many others, have become very active. Today, the piano art of Taiwan is the most important part of not only Chinese, but also world music culture. Conclusions. The study of the origins of the piano art of Taiwan, the periods of its development, ways of refracting different musical traditions will help to understand both the historical-theoretical and aesthetic-pedagogical and artistic significance of this phenomenon in musical art. The most important events in the social and cultural life of Taiwan, since the end of the 16th century, indirectly affected the development of national piano art, which underwent qualitative changes connected with the emergence of new musical forms and means of expression, the methods of using the national and Western compositional techniques. The prospect of further study of the topic consists in a more detailed study of the modern stage of developing piano art in Taiwan and clarifying the influence of its extensive genetic roots on the compositional and performing creativity of representatives of Taiwanese musical culture.
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Han, Jae-Young, and Tuyen Nguyen. "AN OVERVIEW ON THE SOPHISTICATION OF THE MING DYNASTY’S PEOPLE THROUGH “HUA-YI-YI-YU”." Journal of General Education 3 (June 30, 2016): 177. http://dx.doi.org/10.24173/jge.2016.06.3.177.
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Han, Younggyu. "Yi Ok’s Literary Inclinations and Distance from Yu Deuk-gong." Journal of Humanities 77 (May 30, 2020): 5–40. http://dx.doi.org/10.31310/hum.077.01.
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Peralta, Eigen, Dan Lu, Mark Landon, Hui-Yi Chu, Amit Mehta, Philip Chu, Alec Witty, Tom Lee, and Bahram Valamehr. "Abstract 5513: Chimeric CD3 fusion receptors expressed on iPSC-derived universal TCR-less CAR-T and -NK cells synergize with bispecific engagers to enhance antitumor activity and limit antigen escape." Cancer Research 82, no. 12_Supplement (June 15, 2022): 5513. http://dx.doi.org/10.1158/1538-7445.am2022-5513.
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Abstract Despite success in hematologic malignancies, chimeric antigen receptor (CAR) T cells have been less effective in solid tumors, in part because of the heterogeneous expression of the CAR-specific target antigen (1° Ag) found within the tumor mass. In combination with a CAR, bispecific T cell engagers (BiTEs) can target additional tumor antigens (2° Ag) while engaging CD3 signaling molecules on T cells, providing a unique way to address tumor heterogeneity, mitigate antigen escape and further potentiate durable effector function. However, in generating off-the-shelf universal CAR-T and NK cells, a combination strategy is not feasible as neither modified cell product is compatible to specifically engage with a BiTE. In developing allogeneic CAR-T cells, the T cell receptor (TCR) surface expression must be eliminated to prevent graft versus host disease, but the absence of surface TCR expression leads to loss of surface CD3 expression and BiTE compatibility. Similarly, NK cells naturally lack TCR expression and have no surface CD3 molecules for BiTE engagement. Here we discuss the development of a novel chimeric CD3ε fusion receptor (CD3-CFR) with a modified transmembrane and endodomain enabling surface expression in TCR-less T or NK cells, allowing for a novel combinatorial solution between universal CAR-T or NK cells with BiTEs in an allogeneic setting. CD3-CFR signal transduction was initially investigated in TRAC knockout NFAT reporter (T-KO) Jurkat cells engineered with CD3-CFR and co-cultured with EpCAM+ target cells. When soluble EpCAM-BiTE was added to the co-culture, the observed 6.9-fold increase in NFAT activity indicated successful engagement associated with the interaction of CD3-CFR, target cells and the BiTE. CD3-CFR T-KO Jurkat cells were further modified to secrete the EpCAM-BiTE and showed increased NFAT activity, demonstrating the feasibility of self-secreting BiTE-mediated targeting through CD3-CFR signaling. We next engineered CD3-CFR expressing iPSC-derived CAR-T (iT) cells to show preserved T cell differentiation kinetics and maintained CAR activity against 1° Ag positive targets (>90% cytolysis). Importantly, while CAR-iT cells showed only background lysis of 1° Ag negative tumor cells, CD3-CFR+ CAR-iT cells were able to lyse ~99% of 1° Ag negative tumor cells with the addition of soluble EpCAM-BiTE targeting the 2° Ag. When CD3-CFR+ CAR-iT cells were further engineered to secrete the EpCAM-BiTE, CD3-CFR+ BiTE+ CAR-iT cells demonstrated superior killing of heterogenous tumors compared to CD3-CFR+ BiTE- CAR-iT cells (70% vs. 5% cytolysis). Taken together these data demonstrate for the first time that CD3 expression and BiTE engagement can be combined in a universal iPSC-derived CAR-iT cell product to overcome antigen heterogeneity and enhance efficacy in solid tumor settings. Citation Format: Eigen Peralta, Dan Lu, Mark Landon, Hui-Yi Chu, Amit Mehta, Philip Chu, Alec Witty, Tom Lee, Bahram Valamehr. Chimeric CD3 fusion receptors expressed on iPSC-derived universal TCR-less CAR-T and -NK cells synergize with bispecific engagers to enhance antitumor activity and limit antigen escape [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 5513.
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Hu, Suhua. "The split word orders APV and PAV of Nuosu Yi." Asian Languages and Linguistics 2, no. 1 (July 30, 2021): 36–79. http://dx.doi.org/10.1075/alal.20011.hu.
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Abstract Nuosu Yi is a Tibeto-Burman (henceforth TB) language lacking sufficient core case markers. Depending on the telicity and aspectuality of the predicates, its basic word order splits into APV and rigid PAV. To be specific, the atelic and/or imperfective predicates are APV, while the telic predicates indicated by the resultativity or perfect aspect are PAV. This paper describes the semantics and syntax of the syntactic PAV and APV of Nuosu Yi thoroughly; and compares them to other TB languages in terms of role marking strategies. I propose that the conditions of split word order in Nuosu Yi are on a par with those of the split ergativity encoded by the morphological marking in Tibetan and some other TB languages; namely, the rigid PAV corresponds to the ergative alignment, and the rigid APV corresponds to the accusative alignment. The study will deepen Nuosu Yi’s morpho-syntax study and show the word order diversity to the studies of linguistic typology. Additionally, the study sheds light on the possibility of extending the definition of ergativity and its potential counterpart.
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Song, Yuntao, Anrong Li, Hui Li, Xianfeng Li, Zeao Huang, Junbao Yang, Yi Ding, and Grace Szu. "Abstract 2094: Conjugates of TLR9 and STING agonists achieved profound synergistic effects in vitro and in vivo." Cancer Research 82, no. 12_Supplement (June 15, 2022): 2094. http://dx.doi.org/10.1158/1538-7445.am2022-2094.
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Abstract Introduction: Both Toll-like receptor 9 (TLR9) and STING pathways are two important pathways involved in immune activation. We reasoned that concurrent activation of TLR9 and STING pathways could activate immunity with an efficacy and safety profile that could not be achieved by activating either pathway alone, and we designed a series of conjugates where TLR9 and STING agonists were linked together by a releasable or stable linker. The conjugates have been evaluated in in vitro assays and in vivo mouse models in comparison with TLR9 agonist or STING agonist alone and combination of the two agonists. Methods: Cellular potency was assessed using THP-1 monocyte cells and human PBMC. In vivo efficacy was evaluated in mouse tumor models, where tumor cells were inoculated into either the right flank or both flanks of C57BL/6 or BALB/c mice, test compounds were injected intratumorally into the right flank three times at every three days when tumors reached a volume of 90-100 mm3, muDX400 was dosed via IP injection six times at every four days. In MC38 murine model, compounds-treated mice free from tumor for 30 days were re-challenged with MC38 tumor cells. Results: Conjugates CS-2554, 2571 and 2600 showed five to ten folds improvement in potency over the corresponding STING agonist alone or a mixture of the corresponding STING and TLR9 agonists (1/1molar ratio) in THP1 assay, a similar fold of increase in EC50 was observed in human PBMC assay, where induction of IFNα, IFNβ, TNFα and IL6 were measured. In MC38 murine model, CS-2554 at the dose of 9 ug/injection resulted in CR in all treated mice; whereas no CR was obtained when a mixture of an equivalent amount of the corresponding STING agonist and TLR9 agonist was used. The tumor-free mice remained tumor-free after re-challenge study. In MC38 dual tumor model, when combined with aPD-1, a mixture of 50 ug of TLR9 agonist and 5 ug of STING agonist resulted in CR in 38% treated mice, whereas the same level was achieved with only 4 ug of the corresponding conjugate CS-2571. Comparisons of a conjugate and either the corresponding agonist alone or the two in combination were also carried out in CT26 dual tumor model. On day 13, for the injected tumor, the tumor growth inhibition rate (TGI) of an equivalent amount of a TLR9 agonist, a STING agonist, a mixture of the two, and the corresponding conjugate CS-2600 was 29.65%, 31.3%, 61.00%, and 91.93%, respectively. For the distal tumor, only the conjugate CS-2600 showed significant inhibition of tumor growth with 57% TGI, whereas no tumor growth inhibition was observed with a TLR9 agonist, a STING agonist, or a mixture of the two. Conclusions: The conjugates harnessed significant synergy between TLR9 and STING pathways in vitro and in vivo and resulted in over ten times enhancement of potency in certain assays over either agent alone or a combination of the two. The preclinical studies of the conjugates support clinical evaluation of this class of novel compounds. Citation Format: Yuntao Song, Anrong Li, Hui Li, Xianfeng Li, Zeao Huang, Junbao Yang, Yi Ding, Grace Szu. Conjugates of TLR9 and STING agonists achieved profound synergistic effects in vitro and in vivo [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 2094.
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Yin, Zhou-An, Ya-Nan Mao, Yuan-Yuan He, Ling Long, Cheng-Yu Luo, Yue-Xi Wen, Jian-Jun Ouyang, and Zhen-Yi Yuan. "An Experimental Study on the Mechanisms of Ge Hua Jie Cheng Decoction for Rats with Alcoholic Liver Injuries." Journal of Acupuncture and Herbs 3, no. 1 (November 1, 2015): 60–64. http://dx.doi.org/10.1515/tcm-2015-0008.
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Abstract Objective: To explore the effects and underlying mechanisms of Ge Hua Jie Cheng Decoction on rats with alcoholic liver injuries. Methods: 60 Wistar rats were randomly assigned to six groups: normal group, model group, Yi Gan Ling group, and Ge Hua Jie Cheng Decoction groups in low, middle and high concentrations, 10 rats in each group. Except for the normal group, rats in other groups were administered white wine for eight weeks to establish the liver injury model. During the modeling, the Yi Gan Ling/Ge Hua Jie Cheng Decoction were administered intragastrically to the rats. So the histopathological changes were observed after eight weeks, meanwhile the serum γ- glutamyl endopeptidase (GGT), Glutathione (GSH) and aspartate aminotransferase mitochondrial isoenzyme (m-AST) were assayed by automatic biochemical analyzer. Results: under the light microscope, the groups of high and middle dosages of Ge Hua Jie Cheng Decoction , especially the high one, had apparent improvement of inflammatory infiltration in liver tissues. Compared with the normal group, the serum GGT and m-AST levels had elevated (P＜0.01), whereas the serum GSH level decreased (P＜0.01); compared with model group, the high and middle dosages of Ge Hua Jie Cheng Decoction groups had decreased serum GGT and m-AST (P＜0.01 or P＜0.05), as well as increased serum GSH level (P＜0.01). Conclusion: Ge Hua Jie Cheng Decoction has a protective effect for liver injuries induced by alcohol, and this effect is dose-dependent. The high dosage showed stronger protection effect, which might be related to the increased serum GSH and decreased serum GGT and m-AST.
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Seo, Geun-Sik. "The Study on Danchijeom(｢斷時占｣) and “Hado”(｢河圖｣)･“Naksu”(｢洛書｣) of Yi Joo-Cheon(李柱天)." Institute of Korean Cultural Studies Yeungnam University 81 (August 31, 2022): 365–90. http://dx.doi.org/10.15186/ikc.2022.08.31.11.
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In this thesis, Yi Ju-Cheon(李柱天)’s Dansijeom(「斷時占」) was examined.
Dansijeom(「斷時占」) can be said to be one of Saju(四柱)･Myeongrihak(命 理學). Yet, it doesn’t harmonize with his being a Confucian intellectual.
Accordingly, Yi Ju-Cheon(李柱天) thoroughly investigated Dansijeom(「斷 時占」) because he thought that one could reach the highest stage of I-ching(「周易」) and Shujing(「書經」) “Hongfan”(｢洪範｣)｣ of after going through the lowest stage of Dansijeom(「斷時占」) and then “Hado”(｢河圖｣) and “Naksu”(｢洛書｣).
Regarding “Hado”(｢河圖｣) and “Naksu”(｢洛書｣), Yi Ju-Cheon(李柱天) usually mentioned imperfect “Naksu”(｢洛書｣). He was interested in “Naksu”(｢洛書｣) in this way because Dansijeom(「斷時占」) was raunch and incomplete. The number nine in “Naksu”(｢洛書｣) is connected to Gusung(九星) and Gugung(九宮), etc. And Gusung(九星) and Gugung(九宮) are also linked imperfectly to Bagua(八卦), Wuxing(五行), Fangwei(方位), Tianggan(天干), and Dizhi(地支). Through this, we can imagine what Yi Ju-Cheon(李柱天) was like who intended to pursue all the things in the world.
Yi Ju-Cheon(李柱天) created “Dansijeom fortune-telling method”(｢斷時 占 占法｣) and put it at the end, which made it possible for people to practice divination. It counterpoints the fact that Chu Hsi(朱熹) placed “Shiyi”(｢筮儀｣) at the beginning of Zhouyibenyi(「周易本義」).
In “15 Goe Cheongan Ohaeng Gilhyung”(｢十五卦天干五行吉凶｣), Ipgil (立吉), Iphyung(立凶), Wagil(臥吉), and Wahyung(臥凶) were considered to be similar to Gil(吉)･Hyung(凶)･Hoe(悔)･Ryn(吝) in I-ching(「周易」). It shows that what Yi Ju-Cheon(李柱天) sought was not only in Dansijeom (「斷時占」) but also in I-ching(「周易」).
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Zhi, Chen. "From Exclusive Xia to Inclusive Zhu-Xia: The Conceptualisation of Chinese Identity in Early China." Journal of the Royal Asiatic Society 14, no. 3 (November 2004): 185–205. http://dx.doi.org/10.1017/s135618630400389x.
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This paper involves an syncretic study of the structural characteristics, semantic stratification, graphical evolution and contextual analysis on a chronological base of the perplexing graphs and words which designate the Chinese, such as xia, hua and zhongguo, non-Chinese, such as yi, di, rong, and man, in early palaeographic and documentary sources. It shows how these terms evolved to distinguish between the two distinct ethnographical concepts in the early mind.The study shows that the conception of Hua-Xia and Zhongguo carried different connotations in the Western Zhou period from that defined in Spring and Autumn philological sources. The relocation of the Zhou capital to the east during the transition from Western to Eastern Zhou had generically diffused the concept of Xia and the elegant Ya culture. The conception of Xia and Yi, which had formerly distinguished between the Zhou elites and the non-Zhou people, came to distinguish between the central states and peripheral groups in the geographical sense, as well as between the Zhou subjects and the non-Zhou subjects in the political sense. Thus the conceptualisation of the so-called “Chinese-ness” postdates the actual formation of the ethnographical bulk of the Chinese people.
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Lin, Xueyang. "On Wang Yi Sun Ci's inheritance and new Change of "Flower paradigm"." BCP Education & Psychology 6 (August 25, 2022): 51–57. http://dx.doi.org/10.54691/bcpep.v6i.1685.
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"Flower paradigm" has a great influence on the development of ci. Wang Yisun, a poetist in the late Song Dynasty, intended to break through the paradigm, but his standard "outside of flowers" was not free from the influence of "between flowers". Compared with Hua Jian, "Hua Wai" is a unique style inherited and newly changed in the relationship between lyric mode and ci meaning. The inheritance and innovation of Bishan ci are embodied in lyrical Angle, emotion, image structure and contrast between ci and meaning. To explore the relationship between Wang Yisun's ci poems and "flower-to-flower paradigm", we can get a glimpse of the origin of the formation of "flower-to-flower paradigm", and also provide a new perspective for us to review "flower-to-flower".
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Sungsan Cho. "Governing Thought of Yi Gang-hoi: An aspect of inheriting Dasan Study." DAEDONG MUNHWA YEON'GU 1, no. 57 (March 2007): 139–69. http://dx.doi.org/10.18219/ddmh.1.57.200703.139.
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Ji, Chang-gyu. "A Theory of Observation of Mind in the Fa-hua-xuan-yi." Journal of Buddhist Thought and Culture 2 (December 2010): 115–52. http://dx.doi.org/10.33521/jbs.2010.2.0.115.
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왕, 더웨이, and Woon-sun Koh. "Constant Change of Hua and Yi: A New Vision on Sinophone Studies." Journal of Modern Chinese Literature 95 (October 31, 2020): 387–441. http://dx.doi.org/10.46487/jmcl.2020.10.95.387.
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Ni, Yong, Yong Ni Shao, and Yong He. "Fast Nondestructive Measurement and Discrimination of Tablet Based on Vis/NIR Spectroscopy and Chemometrics." Applied Mechanics and Materials 48-49 (February 2011): 506–10. http://dx.doi.org/10.4028/www.scientific.net/amm.48-49.506.
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This paper presents methods based on chemometrics analysis to select the optimal model for variety discrimination of ginkgo (Ginkgo biloba L.) tablets by using a visible/short-wave near-infrared spectroscopy (Vis/NIRS) system. The tablet varieties used in the research include Da na kang, Xin bang, Tian bao ning, Yi kang, Hua na xing, Dou le, Lv yuan, Hai wang, and Ji yao. All samples (n=270) were scanned in the Vis/NIR region between 325-1075nm using a spectrograph. Principal component artificial neural network (PC-ANN) was used to identify the tablet varieties. In PC-ANN models, the scores of the principal components were chosen as the input nodes for the input layer of ANN. Independent component analysis (ICA) was executed to select several optimal wavelengths based on loading weights. The absorbance values log (1/R), corresponding to the wavelengths of 481nm, 1000nm, 460nm, 572nm, 658nm, 401nm, 998nm, 996nm, 468nm and 661nm were then chosen as the input data of artificial neural network (IC-ANN), and the discrimination rate was reached at 95.6%, which was better than PC-ANN. The results indicated that ginkgo tablets discrimination was good based on the both methods.
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Lee, Kyungku, and Yeaann Lee. "Two Ways of Dissolving the Hua-Yi Distinction : Hong Daeyong and Sugita Genpaku." Korean Silhak Review 33 (June 30, 2017): 229–61. http://dx.doi.org/10.23945/kss.33.229.261.
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Choi, Byoung Goo. "A Study of Cyborg on the Border: Female, Elderly and Homosexual - Focusing on Yoon Yi-Hyung’s Novels -." Journal of Humanities 83 (November 30, 2021): 79–108. http://dx.doi.org/10.31310/hum.083.03.
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Sato, M. "Bei Yi-hui de Ge-ming Qing-jie--Zai Zhong-ri Liang-guo Cong-shi Ge-ming de Li-cheng (Kita Ikki's Radical Complex: The Course of His Involvement in Chinese and Japanese Revolutions), by Huang Tzu-chin. Taipei: Academia Sinica, 2001, 350 pp., NT$350 (hardcover ISBN 957-671-755-8), 341 pp., NT$300 (paperback ISBN 957-671-756-6)." Social Science Japan Journal 8, no. 1 (September 3, 2004): 131–33. http://dx.doi.org/10.1093/ssjj/jyh046.
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Han, Cong, Zhen Shen, Tao Cui, Shan-shan Ai, Ran-ran Gao, Yao Liu, Gui-yuan Sui, Hong-zhen Hu, and Wei Li. "Yi-Shen-Hua-Shi granule ameliorates diabetic kidney disease by the “gut-kidney axis”." Journal of Ethnopharmacology 307 (May 2023): 116257. http://dx.doi.org/10.1016/j.jep.2023.116257.
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