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Relevant bibliographies by topics / Human abdominal sepsis][Sepsis

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Academic literature on the topic 'Human abdominal sepsis][Sepsis'

Author: Grafiati

Published: 4 June 2021

Last updated: 15 February 2022

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Journal articles on the topic "Human abdominal sepsis][Sepsis"

1

Carlson, G. L., M. Saeed, R. A. Little, and M. H. Irving. "Serum leptin concentrations and their relation to metabolic abnormalities in human sepsis." American Journal of Physiology-Endocrinology and Metabolism 276, no. 4 (1999): E658—E662. http://dx.doi.org/10.1152/ajpendo.1999.276.4.e658.

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Circulating leptin concentrations are raised in animal models of inflammation and sepsis. The purpose of this study was to determine the effect of sepsis on serum leptin concentration in humans and to examine the relationship between leptin and the metabolic consequences of sepsis. Resting energy expenditure, insulin sensitivity, and fasting serum leptin, plasma insulin, and cortisol concentrations were measured in 20 subjects with intra-abdominal sepsis and 20 healthy control subjects, before and during a 2-h period of euglycemic hyperinsulinemia. Fasting serum leptin concentrations were simi

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Pieracci, F. M., and P. S. Barie. "Management of Severe Sepsis of Abdominal Origin." Scandinavian Journal of Surgery 96, no. 3 (2007): 184–96. http://dx.doi.org/10.1177/145749690709600302.

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Severe sepsis is a life-threatening condition that may occur as a sequela of intra-abdominal infections (IAIs) of all types. Diagnosis of IAIs is predicated upon the combination of physical examination and imaging techniques. Diffuse peritonitis usually requires urgent surgical intervention. In the absence of diffuse peritonitis, abdominal computed tomography remains the most useful test for the diagnosis of IAIs, and is essential to both guide therapeutic interventions and evaluate suspected treatment failure in the critically ill patient. Parameters most consistently associated with poor out

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Siegler, Benedikt Hermann, Marc Altvater, Jan Niklas Thon, et al. "Postoperative abdominal sepsis induces selective and persistent changes in CTCF binding within the MHC-II region of human monocytes." PLOS ONE 16, no. 5 (2021): e0250818. http://dx.doi.org/10.1371/journal.pone.0250818.

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Background Postoperative abdominal infections belong to the most common triggers of sepsis and septic shock in intensive care units worldwide. While monocytes play a central role in mediating the initial host response to infections, sepsis-induced immune dysregulation is characterized by a defective antigen presentation to T-cells via loss of Major Histocompatibility Complex Class II DR (HLA-DR) surface expression. Here, we hypothesized a sepsis-induced differential occupancy of the CCCTC-Binding Factor (CTCF), an architectural protein and superordinate regulator of transcription, inside the M

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Koca, Uğur, Çimen Gülben Olguner, Bekir Uğur Ergür, et al. "The Effects of Dexmedetomidine on Secondary Acute Lung and Kidney Injuries in the Rat Model of Intra-Abdominal Sepsis." Scientific World Journal 2013 (2013): 1–11. http://dx.doi.org/10.1155/2013/292687.

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In the present study, the effects of dexmedetomidine on secondary lung and kidney injuries were studied in the rat model of intra-abdominal sepsis by immunohistological and biochemical examinations. We measured serum creatinine, kidney tissue malondialdehide and plasma neutrophil gelatinase-associated lipocalin levels. In order to evaluate tissue injury we determined kidney tissue mononuclear cell infiltration score, alveolar macrophage count, histological kidney and lung injury scores and kidney and lung tissue immunoreactivity scores. We demonstrated that dexmedetomidine attenuates sepsis-in

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Luo, Lingtao, Su Zhang, Yongzhi Wang, et al. "Proinflammatory role of neutrophil extracellular traps in abdominal sepsis." American Journal of Physiology-Lung Cellular and Molecular Physiology 307, no. 7 (2014): L586—L596. http://dx.doi.org/10.1152/ajplung.00365.2013.

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Excessive neutrophil activation is a major component in septic lung injury. Neutrophil-derived DNA may form extracellular traps in response to bacterial invasions. The aim of the present study was to investigate the potential role of neutrophil extracellular traps (NETs) in septic lung injury. Male C57BL/6 mice were treated with recombinant human (rh)DNAse (5 mg/kg) after cecal ligation and puncture (CLP). Extracellular DNA was stained by Sytox green, and NET formation was quantified by confocal microscopy and cell-free DNA in plasma, peritoneal cavity, and lung. Blood, peritoneal fluid, and l

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Zantl, Niko, Annette Uebe, Brigitte Neumann, et al. "Essential Role of Gamma Interferon in Survival of Colon Ascendens Stent Peritonitis, a Novel Murine Model of Abdominal Sepsis." Infection and Immunity 66, no. 5 (1998): 2300–2309. http://dx.doi.org/10.1128/iai.66.5.2300-2309.1998.

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ABSTRACT Despite considerable progress, peritonitis and sepsis remain life-threatening conditions. To improve the understanding of the pathophysiology encountered in sepsis, a new standardized and highly reproducible murine model of abdominal sepsis termed colon ascendens stent peritonitis (CASP) was developed. In CASP, a stent is inserted into the ascending colon, which generates a septic focus. CASP employing a stent of 14-gauge diameter (14G stent) results in a mortality of 100% within 18 to 48 h after surgery. By inserting stents of small diameters, mortality can be exactly controlled. Thu

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Leinhardt, D. J., J. Arnold, K. A. Shipley, M. M. Mughal, R. A. Little, and M. H. Irving. "Plasma NE concentrations do not accurately reflect sympathetic nervous system activity in human sepsis." American Journal of Physiology-Endocrinology and Metabolism 265, no. 2 (1993): E284—E288. http://dx.doi.org/10.1152/ajpendo.1993.265.2.e284.

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Plasma norepinephrine concentrations ([NE]) when raised in patients with sepsis are thought to indicate increased activity of the sympathetic nervous system (SNS). However, increased SNS activity may occur without a concomitant rise in plasma [NE]. Measurement of NE kinetics (clearance and spillover) is a more accurate and direct assessment of SNS activity. In the present study plasma [NE] and NE kinetics were measured in six patients with intra-abdominal sepsis (septic) using tritiated NE infused to achieve a plateau plasma concentration. The measurements were repeated in the same patients af

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Worth, P. J., S. F. Monaghan, R. K. Thakkar, et al. "Compartmentalized Lymphocyte Response To Abdominal Versus Non-abdominal Sources Of Sepsis In Humans." Journal of Surgical Research 165, no. 2 (2011): 238. http://dx.doi.org/10.1016/j.jss.2010.11.505.

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Lehmann, Christian, Maral Aali, Juan Zhou, and Bruce Holbein. "Comparison of Treatment Effects of Different Iron Chelators in Experimental Models of Sepsis." Life 11, no. 1 (2021): 57. http://dx.doi.org/10.3390/life11010057.

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Growing evidence indicates that dysregulated iron metabolism with altered and excess iron availability in some body compartments plays a significant role in the course of infection and sepsis in humans. Given that all bacterial pathogens require iron for growth, that iron withdrawal is a normal component of innate host defenses and that bacterial pathogens have acquired increasing levels of antibiotic resistance, targeting infection and sepsis through use of appropriate iron chelators has potential to provide new therapeutics. We have directly compared the effects of three Food and Drug Admini

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O'Connell, Rachel L., Glenn K. Wakam, Ali Siddiqui, et al. "Development of a large animal model of lethal polytrauma and intra-abdominal sepsis with bacteremia." Trauma Surgery & Acute Care Open 6, no. 1 (2021): e000636. http://dx.doi.org/10.1136/tsaco-2020-000636.

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BackgroundTrauma and sepsis are individually two of the leading causes of death worldwide. When combined, the mortality is greater than 50%. Thus, it is imperative to have a reproducible and reliable animal model to study the effects of polytrauma and sepsis and test novel treatment options. Porcine models are more translatable to humans than rodent models due to the similarities in anatomy and physiological response. We embarked on a study to develop a reproducible model of lethal polytrauma and intra-abdominal sepsis, which was lethal, though potentially salvageable with treatment.MethodsOur

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Dissertations / Theses on the topic "Human abdominal sepsis][Sepsis"

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Vasconcelos, P. R. L. de. "Hepatic metabolism during sepsis." Thesis, University of Oxford, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.233530.

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Lattuada, Marco. "Effect of Ventilatory Support on Abdominal Fluid Balance in a Sepsis Model." Doctoral thesis, Uppsala universitet, Klinisk fysiologi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-207218.

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In patients affected by acute respiratory failure or acute respiratory distress syndrome (ARDS) the leading cause of death is failure of different vital organs other than the lungs, so called multiple organ dysfunction syndrome (MODS). The abdominal organs have a crucial role in the pathogenesis of this syndrome. There is a lack of knowledge regarding the mechanisms by which mechanical ventilation can affect the abdominal compartment. One hypothesis is that mechanical ventilation can interfere with abdominal fluid balance causing edema and inflammation. We addressed the question whether differ

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Bleszynski, Michael Sean. "Impact of open abdomen and Vacuum Assisted Closure Device in surgical abdominal sepsis." Thesis, University of British Columbia, 2017. http://hdl.handle.net/2429/61001.

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Introduction: Surgical abdominal sepsis has traditionally been managed with by a single staged procedure, otherwise known as primary abdominal closure (PAC). An on demand laparotomy may be performed for post-operative clinical deterioration. Open abdomen and a planned re-laparotomy with vacuum assisted closure (VAC) is an alternate method to single staged procedure. Inflammatory cytokines can potentially help stratify severity of sepsis and guide surgical management. The objective of the study was to identify if inflammatory cytokines could differentiate between PAC and VAC. Secondary objectiv

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Perry, Sara Elizabeth. "The phenotypic characterization of the monocyte in human sepsis." Thesis, University of Liverpool, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.268902.

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Sartelli, M., F. M. Abu-Zidan, L. Ansaloni, et al. "The role of the open abdomen procedure in managing severe abdominal sepsis: WSES position paper." BioMed Central, 2015. http://hdl.handle.net/10150/610338.

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The open abdomen (OA) procedure is a significant surgical advance, as part of damage control techniques in severe abdominal trauma. Its application can be adapted to the advantage of patients with severe abdominal sepsis, however its precise role in these patients is still not clear. In severe abdominal sepsis the OA may allow early identification and draining of any residual infection, control any persistent source of infection, and remove more effectively infected or cytokine-loaded peritoneal fluid, preventing abdominal compartment syndrome and deferring definitive intervention and anastomo

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Januszkiewicz, Anna. "In vivo protein synthesis determinations in human immune cells /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-219-5/.

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Cajander, Sara. "Dynamics of Human Leukocyte Antigen-D Related expression in bacteremic sepsis." Doctoral thesis, Örebro universitet, Institutionen för medicinska vetenskaper, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-56125.

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Monocytic human leukocyte antigen-D related (mHLA-DR) expression determined by flow cytometry has been suggested as a biomarker of sepsisinduced immunosuppression. In order to facilitate use of HLA-DR in clinical practice, a quantitative real-time PCR technique measuring HLA-DR at the transcription level was developed and evalutated. Levels of HLA-DR mRNA correlated to mHLADR expression and were robustly measured, with high reproducibility, during the course of infection. Dynamics of mHLA-DR expression was studied during the first weeks of bloodstream infection (BSI) and was found to be depend

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González, Lisorge Ada. "Estudio sobre la sepsis grave de origen abdominal. Utilidad de la procalcitonina y otros marcadores pronósiticos." Doctoral thesis, Universidad de Murcia, 2013. http://hdl.handle.net/10803/128673.

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INTRODUCCIÓN: La sepsis es una de las principales causas de morbimortalidad en las unidades de cuidados intensivos (UCIs). La sepsis grave de origen abdominal es uno de los cuadros más frecuentes en las UCIs Posquirúrgicas. Su mortalidad es elevada y oscila entre 40% y el 70% según las series. Sin embargo, es un cuadro que suele tener poco protagonismo en la literatura científica. Los biomarcadores son elementos fundamentales para el diagnóstico, seguimiento y pronóstico de la sepsis. Uno de los biomarcadores más estudiados en las últimas décadas ha sido la procalcitonina. Muchos autores consi

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Smith, Laura Ann. "Effects of Bacterial Products on Human Blood Leukocytes." University of Toledo Health Science Campus / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=mco1164046331.

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Lima, Erica Silva. "Efeito da suplementação dietética com L-glutamina na sepse abdominal induzida em rato." Universidade do Estado do Rio de Janeiro, 2012. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=5869.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico<br>Após o estímulo deflagrador de um trauma ou infecção, a liberação de citocinas na circulação sanguínea desempenha um importante papel efetor e também modulador da resposta imune sistêmica. Essas citocinas podem ser pró-inflamatórias, que estimulam a liberação de diversos tipos celulares e de outras citocinas, como fator de necrose tumoral-alfa (TNF-α), interleucina 1 (IL-1), IL-2, IL-6, IL-8, IL-12 e interferon-gama (INF-); ou citocinas com efeitos antiinflamatórios, que inibem o processo inflamatório, em parte pela

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Books on the topic "Human abdominal sepsis][Sepsis"

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Sartelli, Massimo, Matteo Bassetti, and Ignacio Martin-Loeches, eds. Abdominal Sepsis. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-59704-1.

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Sartelli, Massimo, Matteo Bassetti, and Ignacio Martin-Loeches. Abdominal Sepsis: A Multidisciplinary Approach. Springer, 2018.

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Sartelli, Massimo, Matteo Bassetti, and Ignacio Martin-Loeches. Abdominal Sepsis: A Multidisciplinary Approach. Springer, 2019.

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Evans, Charlotte, Anne Creaton, Marcus Kennedy, and Terry Martin, eds. Sepsis. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198722168.003.0011.

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Sepsis is common and has been the focus of recent large-scale, multi-centre trials internationally. Mortality rates have improved, largely due to a focus on early identification, key interventions, and close monitoring. Setting goals and resuscitation targets coupled with frequent reassessment is the essence of modern sepsis care. Retrieval services bring the intensive care unit to the patient. Specific conditions such as infective endocarditis, central nervous system infections, respiratory, gastrointestinal, abdominal, obstetric, and necrotizing soft tissue sepsis require special considerati

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Doyle, Jeffrey D., and John C. Marshall. Intra-abdominal sepsis in the critically ill. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0187.

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Intra-abdominal infection encompasses a broad group of infections arising both within the peritoneal cavity and the retroperitoneum. The probable bacteriology reflects patterns of normal and pathological colonization of the gastrointestinal tract. Anaerobic bacteria are found in the distal small bowel and colon. The abdomen is the second most common site of infection leading to sepsis in critically-ill patients. Intra-abdominal infections can be complex to manage and require excellent collaboration between intensivists, diagnostic and interventional radiologists, surgeons, and sometimes gastro

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Thomson, D., and M. W. Wuechler. Abdominal Sepsis (Digestive Surgery, Vol. 13, No.4-5, 1996). S Karger Pub, 1996.

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Waldmann, Carl, Neil Soni, and Andrew Rhodes. Gastrointestinal disorders. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199229581.003.0020.

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Vomiting and gastric stasis/gastroparesis 318Gastric erosions 320Diarrhoea 322Upper gastrointestinal haemorrhage (non-variceal) 324Bleeding varices 326Intestinal perforation 328Intestinal obstruction 330Lower gastrointestinal bleeding 332Colitis 334Intra-abdominal sepsis 336Pancreatitis 338Acute acalculous cholecystitis 340Splanchnic ischaemia 342Abdominal hypertension (IAH) and abdominal compartment syndrome ...

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Moshe, Schein, and Wise Leslie, eds. Cytokines and the abdominal surgeon. R.G. Landes, 1998.

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Gardiner, Matthew D., and Neil R. Borley. Emergency surgery. Oxford University Press, 2012. http://dx.doi.org/10.1093/med/9780199204755.003.0008.

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This chapter begins by discussing the basic principles of Advanced Trauma Life Support, care of the critically ill surgical patient, shock, SIRS and sepsis, and blood products and transfusion, before focusing on the key areas of knowledge, namely traumatic head injury, spine and spinal cord trauma, maxillofacial trauma, cardiothoracic trauma, abdominal trauma, urological trauma, vascular trauma, assessment of the acute abdomen, acute appendicitis, acute upper gastrointestinal haemorrhage, lower gastrointestinal haemorrhage, gastrointestinal obstruction, gastrointestinal perforation, acute panc

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Johnson, Steven B. Pathophysiology and management of abdominal injury. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0334.

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Abdominal injuries are common following blunt and penetrating trauma. They can result in a spectrum of severity from benign to potentially life-threatening conditions. Soon after injury, haemorrhage is the predominant concern, and leading cause of morbidity and mortality. Active haemorrhage resulting in shock requires emergent operative intervention and aggressive haemostatic resuscitation. However haemodynamically-stable patients benefit from non-operative management of solid organ injuries with or without angiographic embolization. Sepsis usually occurs as a result of intra-abdominal infecti

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Book chapters on the topic "Human abdominal sepsis][Sepsis"

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Champion, Howard R., Nova L. Panebianco, Jan J. De Waele, et al. "Abdominal Sepsis." In Encyclopedia of Intensive Care Medicine. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-00418-6_1024.

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Shin, Reuben D., and Peter W. Marcello. "Intra-abdominal Sepsis." In Surgical Intensive Care Medicine. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-19668-8_31.

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Metze, Dieter, Tam Nguyen, Birgit Haack, et al. "Diffuse Abdominal Sepsis." In Encyclopedia of Molecular Mechanisms of Disease. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_6560.

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Brozovich, Marc E., and Peter W. Marcello. "Intra-abdominal Sepsis." In Surgical Intensive Care Medicine. Springer US, 2010. http://dx.doi.org/10.1007/978-0-387-77893-8_30.

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Clarke, D. P., and J. R. Buscombe. "Imaging Abdominal Sepsis." In The Imaging of Infection and Inflammation. Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-011-4990-7_9.

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Marcello, Peter W. "Intra-Abdominal Sepsis." In Surgical Intensive Care Medicine. Springer US, 2001. http://dx.doi.org/10.1007/978-1-4757-6645-5_28.

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De Waele, Jan J., and Inneke De laet. "Intra-Abdominal Hypertension and MODS." In Sepsis Management. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-03519-7_6.

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Preiser, Jean-Charles, and Jean-Louis Vincent. "Sepsis." In Metabolism of Human Diseases. Springer Vienna, 2014. http://dx.doi.org/10.1007/978-3-7091-0715-7_46.

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May, Addison K. "Treatment of Abdominal Sepsis." In Intensivist Should Know. CRC Press, 2021. http://dx.doi.org/10.1201/9781003042136-30.

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Ryan, Thomas, and John D. Coakley. "Adjunctive Therapies in Abdominal Sepsis." In Hot Topics in Acute Care Surgery and Trauma. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-59704-1_23.

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Conference papers on the topic "Human abdominal sepsis][Sepsis"

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Hedenstierna, G., M. Lattuada, and E. Maripuu. "Mechanical Ventilation Worsens Abdominal Edema in Experimental Sepsis." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a4665.

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Gutsche, Markus, Vikram Sahni, Daya Upadhyay, Frank T. Kagawa, and Sharmila Pramanik. "Eosinopenia With Abdominal Pain And Sepsis In HIV." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a6181.

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Fuss, Yu O., A. O. Voloboyeva, and V. P. Polovyj. "Signs of abdominal sepsis in patients with generalized peritonitis." In SCIENTIFIC PROGRESS OF MEDICINE AND PHARMACY OF THE EU COUNTRIES. Baltija Publishing, 2021. http://dx.doi.org/10.30525/978-9934-26-075-9-27.

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Bustamante, A. C., K. Opron, T. J. Standiford, and B. Singer. "Transcriptomic Profiles of Sepsis in the Human Brain." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2387.

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Li, Yumei, Wenli Zhou, Jiantao Zhang, and Chaoying Yan. "Clinical analyses of neonatal sepsis caused by Listeria monocytogene." In 2011 International Conference on Human Health and Biomedical Engineering (HHBE). IEEE, 2011. http://dx.doi.org/10.1109/hhbe.2011.6027980.

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Doerschug, K., A. Delsing, G. Schmidt, and A. Ashare. "Renin-Angiotensin System Activation Correlates with Microvascular Dysfunction in Human Sepsis." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a1139.

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Xu, Jianqiao, and Lixin Xie. "Dynamic changes of monocyte human leukocyte antigen-DR and T cell subsets in sepsis." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.oa2926.

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Urooj, F., P. Flinders, J. Paul, and B. Padmakumar. "G167(P) A case series of human parechovirus associated sepsis and meningitis in young children." In Royal College of Paediatrics and Child Health, Abstracts of the RCPCH Conference and exhibition, 13–15 May 2019, ICC, Birmingham, Paediatrics: pathways to a brighter future. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2019. http://dx.doi.org/10.1136/archdischild-2019-rcpch.162.

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Fang, Yen-Ling, Wen-Bin Lee, Chih-Hung Wang, et al. "An Integrated Microfluidic System for Fast Isolation of Bacteria in Human Whole Blood for Diagnosis of Sepsis." In 2020 IEEE 33rd International Conference on Micro Electro Mechanical Systems (MEMS). IEEE, 2020. http://dx.doi.org/10.1109/mems46641.2020.9056344.

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Parekh, Dhruv, Jaimin Patel, Sian Lax, et al. "LSC Abstract – Vitamin D deficiency is associated with and influences the severity of human and murine sepsis." In ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.pp240.

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