Academic literature on the topic 'Human abnormal growth'

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Journal articles on the topic "Human abnormal growth"

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Velegrakis, Alexandros, Maria Sfakiotaki, and Stavros Sifakis. "Human placental growth hormone in normal and abnormal fetal growth." Biomedical Reports 7, no. 2 (2017): 115–22. http://dx.doi.org/10.3892/br.2017.930.

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Khong, TY, and IH Sawyer. "The human placental bed in health and disease." Reproduction, Fertility and Development 3, no. 4 (1991): 373. http://dx.doi.org/10.1071/rd9910373.

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The morphology of the human placental bed is reviewed. The pathological features seen in spontaneous abortion, pregnancy-induced hypertension, intrauterine growth retardation, placenta accreta and postpartum haemorrhage suggest that abnormal placentation may be a common feature. A defect in the normal materno-trophoblastic interaction is implicated in the pathogenesis of abnormal placentation.
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Kim, Soung Min, Young Joon Lee, Sang Shin Lee, et al. "Abnormal Maxillary Trapezoid Pattern in Human Fetal Cleft Lip and Palate." Cleft Palate-Craniofacial Journal 45, no. 2 (2008): 131–40. http://dx.doi.org/10.1597/06-077.1.

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Objective: To elucidate abnormal growth patterns of human fetal maxillae with cleft lip and palate (CLP). Subject: A total of 71 fetal maxillae with CLP were obtained from aborted human fetuses. Method: Dimensions of the maxillary trapezoid (MT), formed by the maxillary primary growth centers (MxPGC), were taken from radiographic images. The CLP dimensions were compared with maxillary trapezoid dimensions of normal fetuses from a previous study (Lee et al., 1992). Main Outcome Measures: Cleft lip subjects without a cleft palate, unilateral cleft lip-alveolar cleft or cleft palate (UCL+A/UCLP),
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Schulman, S., E. F. Roth, B. Cheng, et al. "Growth of Plasmodium falciparum in human erythrocytes containing abnormal membrane proteins." Proceedings of the National Academy of Sciences 87, no. 18 (1990): 7339–43. http://dx.doi.org/10.1073/pnas.87.18.7339.

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Bonkhoff, H., and Klaus Remberger. "Morphogenetic concepts of normal and abnormal growth in the human prostate." Virchows Archiv 433, no. 3 (1998): 195–202. http://dx.doi.org/10.1007/s004280050236.

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Lewis, Aaron M., Melissa Yu, Stephen J. DeArmond, William P. Dillon, Bruce L. Miller, and Michael D. Geschwind. "Human Growth Hormone–Related Iatrogenic Creutzfeldt-Jakob Disease With Abnormal Imaging." Archives of Neurology 63, no. 2 (2006): 288. http://dx.doi.org/10.1001/archneur.63.2.288.

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Murthi, Padma, Gayathri Rajaraman, Shaun Patrick Brennecke, and Bill Kalionis. "The Role of Placental Homeobox Genes in Human Fetal Growth Restriction." Journal of Pregnancy 2011 (2011): 1–11. http://dx.doi.org/10.1155/2011/548171.

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Fetal growth restriction (FGR) is an adverse pregnancy outcome associated with significant perinatal and paediatric morbidity and mortality, and an increased risk of chronic disease later in adult life. One of the key causes of adverse pregnancy outcome is fetal growth restriction (FGR). While a number of maternal, fetal, and environmental factors are known causes of FGR, the majority of FGR cases remain idiopathic. These idiopathic FGR pregnancies are frequently associated with placental insufficiency, possibly as a result of placental maldevelopment. Understanding the molecular mechanisms of
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Tsitsiloni, O. E., J. Stiakakis, A. Koutselinis, et al. "Expression of alpha-thymosins in human tissues in normal and abnormal growth." Proceedings of the National Academy of Sciences 90, no. 20 (1993): 9504–7. http://dx.doi.org/10.1073/pnas.90.20.9504.

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Einstein, Francine, Reid F. Thompson, Hye Heo, et al. "600: Abnormal intrauterine growth induces global epigenetic changes in human stem cells." American Journal of Obstetrics and Gynecology 199, no. 6 (2008): S173. http://dx.doi.org/10.1016/j.ajog.2008.09.630.

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Vijayakumar, Soundarapandian, Suparna Dang, M. Peter Marinkovich, et al. "Aberrant expression of laminin-332 promotes cell proliferation and cyst growth in ARPKD." American Journal of Physiology-Renal Physiology 306, no. 6 (2014): F640—F654. http://dx.doi.org/10.1152/ajprenal.00104.2013.

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Basement membrane abnormalities have often been observed in kidney cysts of polycystic kidney disease (PKD) patients and animal models. There is an abnormal deposition of extracellular matrix molecules, including laminin-α3,β3,γ2 (laminin-332), in human autosomal dominant PKD (ADPKD). Knockdown of PKD1 paralogs in zebrafish leads to dysregulated synthesis of the extracellular matrix, suggesting that altered basement membrane assembly may be a primary defect in ADPKD. In this study, we demonstrate that laminin-332 is aberrantly expressed in cysts and precystic tubules of human autosomal recessi
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Dissertations / Theses on the topic "Human abnormal growth"

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Cherukupalli, Kamala. "Studies on the normal and abnormal lung growth in the human and in the rat with emphasis on the connective tissue fibers of the lung." Thesis, University of British Columbia, 1989. http://hdl.handle.net/2429/30607.

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Infants with bronchopulmonary dysplasia (BPD), showed impaired body growth when compared to control infants. In terms of changes in the biochemical composition of the lung, BPD infants had higher DNA, soluble protein, collagen and desmosine contents as well as increased concentrations of DNA, collagen and desmosine in their lungs when compared to the growth patterns obtained for the lungs of control infants. Pathologically BPD was classified into 4 grades. Grade I BPD, was a phase of acute lung injury, grades II and III were proliferative phases. In grade IV BPD, lung structure returned toward
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"Abnormal skeletal growth and bone remodeling in adolescent idiopathic scoliosis: a morphological and genetic study." Thesis, 2006. http://library.cuhk.edu.hk/record=b6074117.

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Adolescent idiopathic scoliosis (AIS) is a complex three-dimensional structural spine deformity with lateral curve and vertebral rotation occurring predominantly in adolescent girls during the peri-pubertal period. The prevalence of AIS is nearly 4% in Hong Kong and 2-3% worldwide. AIS without treatment or with improper treatment may deteriorate progressively and lead to significant cosmetic problems and functional disabilities. In severe cases, increased mortality rate can result from the associated early onset of cardiopulmonary failure. Up to now, the treatment of the AIS is basically passi
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"Abnormal bone mineralization in adolescent idiopathic scoliosis and its relation with plasma and tissue expression of osteopontin." 2012. http://library.cuhk.edu.hk/record=b5549402.

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青少年特發性脊柱側凸(Adolescent idiopathic scoliosis , AIS)是一種複雜的脊柱三維畸形,常見於10-16 歲處於生長發育高峰期的青少年女性。儘管AIS 發生率較高並且臨床影響較大,但是到目前為止其病因未明。在眾多關於AIS 病因學的假設和理論研究中,普遍認為低骨密度是AIS 的一個重要影響因素。然而近年來對於AIS 患者低骨密度研究不足,其潛在的機制尚不明確。我們之前初步的組織學研究發現,AIS 患者的松質骨中成骨細胞功能下降,此研究為AIS中存在骨礦化異常提供了初步依據。<br>骨橋蛋白是骨組織中一種重要的非膠原細胞外基質蛋白,其在骨礦化過程中起著重要作用。近期的研究報導AIS 患者血漿中骨橋蛋白水準高於年齡匹配的正常對照。因此本研究假設AIS 患者血漿及骨組織中骨橋蛋白高於正常對照,并可能影響了骨基質的礦化,從而導致低骨密度。<br>本系列研究的第一部分旨在通過外周定量電腦斷層掃描(pQCT)明確AIS患者中皮質骨密度及松質骨密度是否均低於正常對照。pQCT 可以準確地三維評估皮質骨密度,松質骨密度及其他骨品質的相關參數。採用雙能X 線骨密度儀(DXA)測量受試者的非優勢側近端股骨面積骨密度(包括股骨頸,Ward’s 三角及大轉子)。而採用pQCT 測量受試者非優勢側橈骨遠端容積骨密度,包括皮質骨密度及松質骨密度。結果顯示AIS 患者面積骨密
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Book chapters on the topic "Human abnormal growth"

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Yoshida, Kazuhiro, Wataru Yasui, Yoshihiro Kagawa, and Eiichi Tahara. "Multiple Genetic Alterations and Abnormal Growth Factor Network in Human Esophageal Carcinomas." In Molecular Pathology of Gastroenterological Cancer. Springer Japan, 1997. http://dx.doi.org/10.1007/978-4-431-65915-0_4.

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Sommerfelt, Maja A., and Robin A. Weiss. "Retroviral Receptors and Interference on Human Cells." In Vectors as Tools for the Study of Normal and Abnormal Growth and Differentiation. Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74197-5_13.

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Dick, John E. "Genetic Manipulation of Human Hematopoietic Stem Cells." In Vectors as Tools for the Study of Normal and Abnormal Growth and Differentiation. Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74197-5_20.

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Reisman, David, and Varda Rotter. "Analysis of Transcriptional Regulatory Regions of The Human p53 Gene in Human Cells Using An EBV-Derived Shuttle Vector." In Vectors as Tools for the Study of Normal and Abnormal Growth and Differentiation. Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74197-5_37.

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Dzierzak, Elaine A., and Richard C. Mulligan. "Human β-Globin Expression in Murine Bone Marrow Transplant Recipients Reconstituted with Retrovirally Transduced Stem Cells." In Vectors as Tools for the Study of Normal and Abnormal Growth and Differentiation. Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74197-5_19.

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Anwar, Suzan, Arthur Rahming, Mikea Fernander, Otito Udedibor, and Shereen Ali. "Breast Cancer Diagnosing System: Using a Rough Set-Ensemble Classifier Approach." In Lecture Notes in Computer Science. Springer Nature Switzerland, 2025. https://doi.org/10.1007/978-3-031-88220-3_2.

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Abstract Breast cancer occurs when normal breast cells turn cancerous, grow abnormally and form tumors. The most common cancer impacting women worldwide is breast cancer. Diagnosing breast cancer early and accurately is crucial for giving the correct treatment and ensuring patients receive the best care possible. Due to human error, misdiagnosis is a possibility in the medical field. Over-diagnosis can cause patients to go through unnecessary treatments. Under-diagnosis can allow malignant tumors to become more aggressive and life-threatening. The aim of our research is to create a dependable
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Tahara, E., W. Yasui, and H. Yokozaki. "Abnormal growth factor networks in neoplasia." In Cell Proliferation in Cancer. Oxford University PressOxford, 1995. http://dx.doi.org/10.1093/oso/9780198547914.003.0006.

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Abstract Human tumours often exhibit aberrant expression or genetic alterations of growth factors and their receptors (Table 6.1), that may confer growth autonomy or interfere with programmed cell death by autocrine, paracrine, and juxtacrine mechanisms. A number of growth factors, receptors, and protein kinases involved in growth factor-induced signalling are encoded by proto-oncogenes (1, 2). Tumour progression and invasion are thought to require the accumulation of multiple growth factor anomalies (3).
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Sun Guang-Quan, Wang William Wei-jun, Yeung Benson Hiu-yan, et al. "Modulation Role of Melatonin in Human Endochondral Ossification." In Studies in Health Technology and Informatics. IOS Press, 2010. https://doi.org/10.3233/978-1-60750-573-0-251.

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Introduction: Melatonin deficiency and abnormal growth have been suggested to be involved in the development of adolescent idiopathic scoliosis (AIS). Multiple functions of melatonin have been described in skeleton system. It was hypothesized that melatonin might modulate endochondral ossification and regulate systemic skeletal growth.
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Sharma, Shubham, Nikhil Kumar Gupta, Ekta Chaudhary, Mr Komal, and Sofi Breezy Minz. "PROSPECTIVE METHOD FOR PRECISE AND AUTOMATED IDENTIFICATION OF BRAIN TUMORS." In Futuristic Trends in Artificial Intelligence Volume 3 Book 8. Iterative International Publisher, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bgai8p2ch8.

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Cancer is one of the most severe disease and it arises because of abnormal growth of cells. Since whole body is consist of cells and because of which there is possibility that there may be abnormal growth of cell in any part of body therefore there are different kind of cancer but in this paper, we are only dealing with brain cancer which is popularly known as brain tumor. Human brain has the capability of decision making and it play a very vital role in our survival. Since human brain is surrounded by hard skull and due to abnormal growth of cell in human brain pressure increase in human skul
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Butler, Gary. "Child and adolescent growth." In Oxford Textbook of Endocrinology and Diabetes. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199235292.003.7005.

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The growth of a human being from a single cell to a fully mature individual is a remarkable process and something that is subject to a large number of influences across the whole growth period. Growth before birth is actually the most rapid and probably the least understood phase, but a detailed description of antenatal events is beyond this chapter. Size at birth, however, is dependent on a number of factors, primarily maternal, in particular the wellbeing of the fetoplacental unit and its level of functioning. This unit is markedly affected in maternal undernutrition, which translates into s
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Conference papers on the topic "Human abnormal growth"

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Kanthou, C., C. Parker, D. E. Huber, et al. "PLATELET-DERIVED GROWTH FACTORA-CHAIN GENE ACTIVATION AND GROWTH FACTOR PRODUCTION BY HUMAN AORTIC SMOOTH MUSCLE CELLS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643751.

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The many contributory factors leading to the development of cardiovascular disease are currently thought to induce a common pathological change involving smooth muscle cells, which migrate from the vessel wall, proliferate,accumulate at the sites of endothelial cell damage, and then secrete connective tissue proteins and lipids which contribute to the plaque which results in the occlusion of the vessel. According to the recently modified hypothesis of Ross (1), a key event in the development of atheroma may be the abnormal release of a number of growth modulatory polypeptides,including platele
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G, Kavitha, Deepa M, Mishal A, Shahira S, and Sharmila Devi S. "Human Pharyngeal Neoplasm Detection using Artificial Intelligence." In International Conference on Modern Trends in Engineering and Management (ICMTEM-24). International Journal of Advanced Trends in Engineering and Management, 2024. http://dx.doi.org/10.59544/bveq1259/icmtem24p6.

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The pharynx plays a most significant role in serving both the body’s air food passageway systems. Pharyngeal neoplasm happens when tissues in the throat grow and spread abnormally, destroying healthy cells. So, pharyngeal neoplasm detection plays a vital role in timely and accurate diagnostic methods for improved patient result outcomes. In this project, we propose a machine learning based classification system for the automated detection of pharyngeal neoplasm using medical imaging data. A convolution neural network (CNN) architecture was designed and trained on the labelled dataset for class
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Kroon, Martin, and Gerhard Holzapfel. "A Theoretical Model for Saccular Cerebral Aneurysm Growth: Deformation and Stress Analysis." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176857.

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Aneurysms are abnormal dilatations of arteries, and these lesions are found almost exclusively in humans. Saccular cerebral aneurysms occur most frequently in the Circle of Willis, which is a circuit of arteries supplying the brain with blood. Aneurysms of this kind appear in a few percent of the human population in the Western world. Only a few percent of these lesions do actually rupture, but once rupture occurs the consequences are severe, often with death as outcome. Once a cerebral aneurysm is detected, clinicians need to decide whether operation is required or not. These decisions are ma
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Bryckaert, M. C., A. Wasteson, M. Lindroth, and G. C. Tobelem. "PLATELET DERIVED GROWTH FACTOR (PDGF) BINDS TO HUMAN BONE MARROW FIBROBLASTS AND STIMULATES THEIR PROLIFERATION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643494.

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A role for the Platelet Derived Growth Factor (PDGF) has been suggested in the abnormal proliferation of bone marrow fibroblasts occuring during myelofibrosis. To investigate this hypothesis, human bone marrow fibroblasts were isolated, and the cultures were characterized by immunofluorescent staining and electron microscopy. Electron microscopy eliminated the presence of endothelial cells by the absence of Weibel-Palade-Bodies. A positive intra and extra cellular antifibro-nectin staining was observed by immunofluorescent staining. The cultured cells didn’t show any labeling with specific ant
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Yalcin, Huseyin C., Huseyin E. Salman, and Reema Y. Kamal. "Assessment of Human Fetal Left Heart Hemodynamics during Prenatal Development." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2021. http://dx.doi.org/10.29117/quarfe.2021.0086.

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The hemodynamic forces and wall shear stresses (WSS) play an important role during the fetal heart development. Abnormal levels of flow-driven shear stress can deteriorate the proper functioning of the cells responsible for the growth and remodeling of the heart and lead to congenital heart defects (CHDs). Hypoplastic left heart syndrome (HLHS) is a critical CHD with severely underdeveloped left ventricle and responsible for 25-40% of all neonatal cardiac deaths. To characterize the main differences between the healthy and HLHS fetal hearts in terms of morphology, flow behavior, and WSS levels
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Mazurkiewicz, Paul. "Accelerated Corrosion of Printed Circuit Boards Due to High Levels of Reduced Sulfur Gasses in Industrial Environments." In ISTFA 2006. ASM International, 2006. http://dx.doi.org/10.31399/asm.cp.istfa2006p0469.

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Abstract Accelerated corrosion leading to system failure has been observed on printed circuit boards present in industrial environments that contain abnormal levels of reduced sulfur gasses, such as hydrogen sulfide (H2S) and elemental sulfur. The problem is compounded by the fact that elemental sulfur is regulated by OSHA as a nuisance dust, and is allowed in a human working environment at the parts per thousand levels. Anecdotal data shows clearly that elemental sulfur gas present at the parts per million level can cause computer systems to fail within 2 months of use. Newer technologies suc
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Rattu, Mohammad A., and Wayne Tamaska. "A Case of HHV-6 Viral Meningitis." In 28th Annual Rowan-Virtua Research Day. Rowan University Libraries, 2024. http://dx.doi.org/10.31986/issn.2689-0690_rdw.stratford_research_day.87.

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Meningitis is the inflammation of the meninges and associated with abnormal cell count in the cerebrospinal fluid (CSF). The lack of bacterial growth in cultures, most commonly referred to as aseptic meningitis, is frequently caused by viruses [2]. Viruses have become more common as the prevalence of bacterial meningitis has decreased secondary to vaccination use, with viral meningitis being the most common form among countries. Viral meningitis will present with fever, headache, photophobia, neck stiffness and nausea and vomiting. Younger children however may not show any signs of meningeal i
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Ochie, Samuel, and Karen Ochie. "Design and Construction of an Air Quality Monitoring System to Mitigate Virus Spread." In SPE Nigeria Annual International Conference and Exhibition. SPE, 2021. http://dx.doi.org/10.2118/208263-ms.

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Abstract Air pollution is one of the most dangerous problems we face in the world today. It causes many illnesses and diseases that affect the immune system of humans and non-human animals and is also a means of propagating the novel COVID-19 or corona virus. Temperature, humidity, and the level of carbon dioxide characterize the air quality in an environment. In addition to abnormal temperatures and humidity causing direct problems to humans like headaches, heatstroke, hypothermia and hyperthermia, death and so on, it could also cause complicated problems like the acceleration of the growth a
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Sharma, Puja, Kevin Sheets, and Amrinder S. Nain. "The Influence of Polymeric Fiber Stiffness and Alignment on Cytoplasmic Bleb Dynamics and Migration of Glioblastoma Multiforme Cells." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80923.

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Cell migration is a tightly regulated phenomenon necessary for regular physiologic processes such as wound healing, immune response, embryonic development, growth, and regeneration [1–3]. Consequences of abnormal migratory behaviors include autoimmune diseases and metastasis during cancer progression [4, 5]. Described as one of the hallmarks of cancer, metastasis is a complex multistep process, and is responsible for 90% of cancer deaths in humans. A better understanding of the process of metastasis is of paramount importance in developing efficient cancer treatment therapies and drugs [6].
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Cavalcante, Francisco Pimentel, Felipe Zerwes, Alessandra Borba, Eduardo Millen, and Antonio Frasson. "The use of blue dye alone for sentinel lymph node biopsy after neoadjuvant chemotherapy in patients with initially node-positive breast cancer." In XXVI Brazilian Mastology Congress. Mastology, 2024. https://doi.org/10.29289/259453942024v34s2016.

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Introduction: Sentinel lymph node biopsy (SLNB) is the gold standard for the evaluation of the axilla in upfront surgery for non-metastatic breast cancer, with a similar recurrence rate and lower morbidity compared to axillary dissection, despite a false-negative rate of around 10%. In patients who underwent neoadjuvant chemotherapy (NACT) and who had initially negative axilla (cN0), the false-negative rate is similar to that found with upfront surgery. Conversely, in patients with non-metastatic breast cancer and initially positive axilla at first presentation (cN1/2) and who achieved complet
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Reports on the topic "Human abnormal growth"

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Splitter, Gary A., Menachem Banai, and Jerome S. Harms. Brucella second messenger coordinates stages of infection. United States Department of Agriculture, 2011. http://dx.doi.org/10.32747/2011.7699864.bard.

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Aim 1: To determine levels of this second messenger in: a) B. melitensiscyclic-dimericguanosinemonophosphate-regulating mutants (BMEI1448, BMEI1453, and BMEI1520), and b) B. melitensis16M (wild type) and mutant infections of macrophages and immune competent mice. (US lab primary) Aim 2: To determine proteomic differences between Brucelladeletion mutants BMEI1453 (high cyclic-dimericguanosinemonophosphate, chronic persistent state) and BMEI1520 (low cyclicdimericguanosinemonophosphate, acute virulent state) compared to wild type B. melitensisto identify the role of this second messenger in esta
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Jalkanen, Jukka-Pekka, Erik Fridell, Jaakko Kukkonen, et al. Environmental impacts of exhaust gas cleaning systems in the Baltic Sea, North Sea, and the Mediterranean Sea area. Finnish Meteorological Institute, 2024. http://dx.doi.org/10.35614/isbn.9789523361898.

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Description: Shipping is responsible for a range of different pressures affecting air quality, climate, and the marine environment. Most social and economic analyses of shipping have focused on air pollution assessment and how shipping may impact climate change and human health. This risks that policies may be biased towards air pollution and climate change, whilst impacts on the marine environment are not as well known. One example is the sulfur regulation introduced in January 2020, which requires shipowners to use a compliant fuel with a sulfur content of 0.5% (0.1% in SECA regions) or use
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