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Dissertations / Theses on the topic 'Human adipose tissue derived adult stem cells'

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1

Ziane, Sophia. "Développement et caractérisation d'un hydrogel thérapeutique pour la régénération du tissu osseux." Thesis, Bordeaux 2, 2012. http://www.theses.fr/2012BOR21930/document.

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Le tissu osseux est caractérisé par sa matrice minéralisée qui est soumise à des activités de formation et de résorption assurant son renouvellement et son remaniement tout au long de la vie. En cas de lésions, l’os est capable de se réparer naturellement de façon à rétablir son intégrité et ses propriétés physiques. Cependant, certaines pathologies ou interventions chirurgicales peuvent aboutir à des pertes massives de substance osseuse et le processus naturel d’autoréparation est alors insuffisant. En première intention, la greffe osseuse est envisagée (autogreffe et allogreffe), néanmoins,
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2

Tsuji, Wakako. "Adipogenesis induced by human adipose tissue-derived stem cells." Kyoto University, 2009. http://hdl.handle.net/2433/126447.

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3

Ferng, Alice S., Katherine M. Marsh, Jamie M. Fleming, et al. "Adipose-derived human stem/stromal cells: comparative organ specific mitochondrial bioenergy profiles." SPRINGER INTERNATIONAL PUBLISHING AG, 2016. http://hdl.handle.net/10150/622736.

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Background: Adipose-derived stem/stromal cells (ASCs) isolated from the stromal vascular fraction are a source of mesenchymal stem cells that have been shown to be beneficial in many regenerative medicine applications. ASCs are an attractive source of stem cells in particular, due to their lack of immunogenicity. This study examines differences between mitochondrial bioenergetic profiles of ASCs isolated from adipose tissue of five peri-organ regions: pericardial, thymic, knee, shoulder, and abdomen. Results: Flow cytometry showed that the majority of each ASC population isolated from the adip
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4

Ito, Ran. "Adipogenesis using human adipose tissue-derived stem cells sustaining release of basic fibroblast growth factor." Kyoto University, 2014. http://hdl.handle.net/2433/188645.

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5

Timper, Katharina. "Human bone marrow- and adipose tissue-derived mesenchymal stem cells differentiate into insulin, somatostatin, and glucagon expressing cells." [S.l. : s.n.], 2007. http://nbn-resolving.de/urn:nbn:de:bsz:25-opus-50498.

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6

Vijayasekaran, Aparna. "Human Adipose Derived Stem Cells (hASC's) and Soft Tissue Reconstruction: Evaluation of Methods for Increasing the Vascularity of Tissue Engineered Soft Tissue Construct." Thesis, The University of Arizona, 2012. http://hdl.handle.net/10150/265352.

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Generation of large volumes to cover an existing soft tissue defect is often complicated by the lack of available tissue. The current options for soft tissue reconstruction include local and free flaps, collagen fillers, traditional fat grafting and other synthetic soft tissue fillers. But they all have limitations. Recently, a lot of interest has been generated regarding the use of human adipose derived stem cells for engineering a biocompatible soft tissue construct. Give their ready availability, viability and plasticity they appear to be the ideal building blocks for a cell based soft tiss
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7

Semon, Julie, Catherine Maness, Xiujuan Zhang, et al. "Comparison of human adult stem cells from adipose tissue and bone marrow in the treatment of experimental autoimmune encephalomyelitis." BioMed Central, 2014. http://hdl.handle.net/10150/610253.

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INTRODUCTION:While administration of ex vivo culture-expanded stem cells has been used to study immunosuppressive mechanisms in multiple models of autoimmune diseases, less is known about the uncultured, nonexpanded stromal vascular fraction (SVF)-based therapy. The SVF is composed of a heterogeneous population of cells and has been used clinically to treat acute and chronic diseases, alleviating symptoms in a range of tissues and organs.METHODS:In this study, the ability of human SVF cells was compared with culture-expanded adipose stem cells (ASCs) and bone-derived marrow stromal cells (BMSC
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8

Volz, Ann-Cathrin Verfasser], and Petra Juliane [Akademischer Betreuer] [Kluger. "Establishment of defined culture conditions for the differentiation, long-term maintenance and co-culture of adipose-derived stem cells for the setup of human vascularized adipose tissue / Ann-Cathrin Volz ; Betreuer: Petra Juliane Kluger." Hohenheim : Kommunikations-, Informations- und Medienzentrum der Universität Hohenheim, 2019. http://d-nb.info/1176020617/34.

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9

Volz, Ann-Cathrin [Verfasser], and Petra Juliane [Akademischer Betreuer] Kluger. "Establishment of defined culture conditions for the differentiation, long-term maintenance and co-culture of adipose-derived stem cells for the setup of human vascularized adipose tissue / Ann-Cathrin Volz ; Betreuer: Petra Juliane Kluger." Hohenheim : Kommunikations-, Informations- und Medienzentrum der Universität Hohenheim, 2019. http://d-nb.info/1176020617/34.

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10

Lalande, Charlotte. "Développement d'un nouveau produit d'ingenierie tissulaire osseuse à base de polymères et de cellules souche du tissu adipeux." Thesis, Bordeaux 2, 2011. http://www.theses.fr/2011BOR21853/document.

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L’ingénierie du tissu osseux vise à concevoir un substitut tissulaire associant des cellules ostéoprogénitrices à une matrice tridimensionnelle capable de promouvoir la reconstruction osseuse, ouvrant la voie au développement de thérapeutiques substitutives à la pratique de la greffe dont les limitations sont bien connues.Le but de ce travail a été de développer un nouveau produit d’ingénierie tissulaire (PIT) destiné à la régénération osseuse constitué i) d’une matrice tridimensionnelle poreuse constituée de polysaccharides naturels biodégradables, ii) de cellules souches adultes issues du ti
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11

Chen, Yentsun, and 陳彥村. "Characterization of Adipose-derived Stem Cells from Adult Human Eyelid Adipose Tissue." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/33502225994937458365.

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碩士<br>國防醫學院<br>生物及解剖學研究所<br>98<br>Stem cells are characterized for the ability to undergo self-renewal and differentiation into multilineage cell type. Owing to easy to harvest with low risk and highly abundant in the human body, adipose-derived stem cells (ASCs) are an attractive source of the adult stem cells. ASCs are then isolated using enzymatic digestion and centrifugation. The pellet is considered containing the stem cells. It can be used directly as a source of stem cells and expanded in culture through many passages. We directed our attention to periocular adipose tissue as a potentia
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12

"Molecular characterization of human adipose tissue-derived stem cells." 2007. http://library.cuhk.edu.hk/record=b5893416.

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Ng, Wing Chi Linda.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2007.<br>Includes bibliographical references (leaves 120-142).<br>Abstracts in English and Chinese.<br>Abstract --- p.i<br>Acknowledgement --- p.iv<br>Publications --- p.v<br>Abbreviations --- p.vi<br>Table of Contents --- p.viii<br>List of Tables --- p.xiii<br>List of Figures --- p.xiv<br>Chapter CHAPTER 1 --- INTRODUCTION --- p.1<br>Chapter 1.1 --- Stem Cells --- p.1<br>Chapter 1.1.1 --- Definition of Stem Cells --- p.1<br>Chapter 1.1.2 --- Different Origins of Stem Cells --- p.2<br>Chapter 1.1.3 --- Challen
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13

Lu, Po-Nien, and 陸柏年. "Adult Adipose Tissue-Derived Stromal Stem Cells Differentiate into Neural-like Cells in Vitro." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/33083157677461307996.

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碩士<br>國立陽明大學<br>口腔生物研究所<br>91<br>暫缺The term “stem cell” means a class of cells, which can self-renew and differentiate into different kinds of cells. The techniques of inducing stem cells to differentiate into all kinds of cells can be applied to repair damaged tissues. Adipose tissue derived stromal stem cell shares the same origin with bone marrow stromal cell, and also has the multi-potential of differentiation like bone marrow stromal cell. However, to acquire adipose tissue derived stromal stem cell is much easier, which makes it become a great replacement of bone stromal stem cell in the
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14

Lin, Tsai-Ming, and 林才民. "Isolation and Characterization of Human Adipose and Lipoma Tissue-derived Mesenchymal Stem Cells." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/42749466720066708619.

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博士<br>高雄醫學大學<br>醫學研究所博士班<br>95<br>Human mesencyhmal stem cells have been isolated from bone marrow and other adult tissues and are potentially useful for tissue engineering. Adipose tissue has several clear advantages as a starting material for harvesting stem cells, as it is abundant and relatively easy to procure, less restriction in law, and molarity or ethic concerns. However, existing methods to expand adipose-derived mesenchymal stem cells are less than optimal. Here we describe a new cell-culture method that accelerates greatly the growth rate and prolongs the lifespan of adipose mesenc
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15

Kan, Li-Ting, and 甘麗婷. "Application of Bio-composite Scaffold in Tissue Engineered Cartilage by Inducing Human Adipose Tissue-derived Stem Cells." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/05599418548338304768.

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碩士<br>國立臺灣科技大學<br>醫學工程研究所<br>98<br>This study investigated the induction of human adipose tissue-derived stem cells (hASCs) into chondrocytes, which made a possible source for cartilage tissue engineering in clinical therapy. The hASCs were cultured on three different biocompatible biomaterial groups including gelatin/collagen I: PCL (GCI), gelatin/collagen II:PCL (GCII) and gelatin:PCL (GP). Considering the high degradability of natural biomaterials, the addition of PCL for formulation of scaffolds is necessary to resist absorption in vitro. In addition, we characterized the attachment, growt
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16

Hanson, Ariel Dawn. "Adhesion and mechanobiology methods to proliferate and osteogenically differentiate human adipose-derived adult stem cells." 2007. http://www.lib.ncsu.edu/theses/available/etd-11082007-213047/unrestricted/etd.pdf.

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17

Mvula, Bernard Dandenault. "Effect of low level laser irradiation on human adult adipose derived stem cells: an in vitro study." Thesis, 2010. http://hdl.handle.net/10210/3085.

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M. Tech.<br>Stem cells are defined as undifferentiated cells that can proliferate indefinitely and have the capacity of both self-renewal and differentiation to one or more types of specialised cells. Traumatic tissue injury and age-related degenerative diseases are a major problem in South Africa and worldwide. Stem cells could be used for tissue engineering and reconstructive surgery. In treating these conditions, the main principle of stem cell therapy is the replacement of damaged and dead cells in injured tissues and organs with new healthy ones expanded in vitro from stem cells (Orlic et
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18

CHEN, HSUAN-YU, and 陳宣妤. "The role of acid extruders and lactate on brown adipogenesis in human adipose tissue-derived stem cells." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/8k86er.

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碩士<br>國防醫學院<br>藥理學研究所<br>107<br>Abstract Backgrounds Obesity is an important global issue, and the top ten causes of death in Taiwan are directly or indirectly related to obesity. The thermogenic capacity of brown or beige adipocyte makes it an attractive therapeutic target for inducing weight loss through energy expenditure. Nowadays, mesenchymal stem cells (MSCs) have gained interests on cell-based therapy by forming brown or beige adipocytes for transplantation to against obesity. Studies showed that keeping higher intracellular pH is important for MSCs to keep the stemness and proliferatio
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19

Correia, Cristina. "Engineering osteochondral tissues with human adipose tissue derived stem cells under precise biomechanical and biochemical in vitro environments." Doctoral thesis, 2012. http://hdl.handle.net/1822/19756.

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Tese de doutoramento em Engenharia Biomédica<br>With the continuous increase in life expectancy, health problems tend to arise, whereas joint ailments are among the most prevalent. The knee joint, in particular, is subjected to serious illnesses that range from articular cartilage injuries, osteochondral lesions and osteoarthritis. Joint pathologies globally affect population of all ages and gender, resulting in reduced quality of life due to limited activity and increased expenditures, either directly (treatment, private expenditure), or indirectly (lost productivity, lost earnings). In
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20

Chen, Yi-Hsuan, and 陳怡璇. "The Influence of Adult Human Adipose-Derived Stem Cells Grafting on Cardiovascular Response under Heatstroke Stimulation in Spinalized Rats." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/87177964358021894059.

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碩士<br>國防醫學院<br>生物及解剖學研究所<br>98<br>Spinal cord injury (SCI) typically results from sustained trauma to the spinal cord, and is often accompanied by irreversible tissue damage, limited endogenous repair as well as permanent loss of motor, sensory and autonomic function. In recent decades, several adult stem cell approaches to spinal cord repair on motor dysfunction have been successfully established in animal models. Using human adipose tissue as a source to isolate stem cells gains advantages for clinical application, like highly abundance within human body and relatively easier harvest with lo
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21

Timper, Katharina [Verfasser]. "Human bone marrow- and adipose tissue-derived mesenchymal stem cells differentiate into insulin, somatostatin, and glucagon expressing cells / vorgelegt von Katharina Timper." 2008. http://d-nb.info/989041972/34.

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22

Mathope, Tebogo Esther. "Effect of low level laser irradiation on human adult adipose derived stem cells and their differentiation into smooth muscle cells – an in vitro study." Thesis, 2011. http://hdl.handle.net/10210/3774.

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M.Tech.<br>Stem cells possess self-renewal capacity, long-term viability, and multilineage potential. Stem cells play important roles in normal physiological and disease processes, they also have great therapeutic potential. However, there have been controversies surrounding stem cells in political, religious and ethical arenas. Although the use of certain stem cells (i.e. embryonic stem cells) and the means by which they are obtained contravene certain basic ethical laws, researchers have developed methods with which to ethically obtain and create stem cell lines. Stem cells can be classified
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23

Lin, Hsiu-Fen, and 林秀芬. "Effect of Transplantation with Cultured Human Adipose Tissue Derived Stem Cells on Rabbits Cornea RepairAfter Alkaline Chemical Burn ---- An Animal Study." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/16432366598597946283.

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碩士<br>高雄醫學大學<br>職業安全衛生研究所<br>97<br>Chemical burn is the absolute ocular emergency. It is the most severe injuries to the organ of vision with a very high percentage of unfavorable outcomes. It often causes extensive damage and results in permanent visual impairment. Recurrent epithelial erosions, symblepharon, corneal scar, corneal ulceration, severe stromal inflammation, and corneal neovascularization are common clinical complications of alkali burn .We studied the effect of cultured human adipose tissue-derived stem cells on regeneration of rabbit cornea after alkaline chemical burn. Human
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