To see the other types of publications on this topic, follow the link: Human biological specimens.

Journal articles on the topic 'Human biological specimens'

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Human biological specimens.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Dutkiewicz, Ewelina P., and Pawel L. Urban. "Quantitative mass spectrometry of unconventional human biological matrices." Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 374, no. 2079 (2016): 20150380. http://dx.doi.org/10.1098/rsta.2015.0380.

Full text
Abstract:
The development of sensitive and versatile mass spectrometric methodology has fuelled interest in the analysis of metabolites and drugs in unconventional biological specimens. Here, we discuss the analysis of eight human matrices—hair, nail, breath, saliva, tears, meibum, nasal mucus and skin excretions (including sweat)—by mass spectrometry (MS). The use of such specimens brings a number of advantages, the most important being non-invasive sampling, the limited risk of adulteration and the ability to obtain information that complements blood and urine tests. The most often studied matrices ar
APA, Harvard, Vancouver, ISO, and other styles
2

Stenhouse, Alan, Nicole Fisher, Brendan Lepschi, et al. "Improving Biological Collections Data through Human-AI Collaboration." Biodiversity Information Science and Standards 7 (September 11, 2023): e112488. https://doi.org/10.3897/biss.7.112488.

Full text
Abstract:
Biological collections play a crucial role in our understanding of biodiversity and inform research in areas such as biosecurity, conservation, human health and climate change. In recent years, the digitisation of biological specimen collections has emerged as a vital mechanism for preserving and facilitating access to these invaluable scientific datasets. However, the growing volume of specimens and associated data presents significant challenges for curation and data management. By leveraging human-Artificial Intelligence (AI) collaborations, we aim to transform the way biological collection
APA, Harvard, Vancouver, ISO, and other styles
3

Metz, C. N., L. Hallihan, R. Wittenstein, and P. K. Gregersen. "COLLECTION OF DE-IDENTIFIED HUMAN BIOLOGICAL SPECIMENS FOR RESEARCH." Journal of Investigative Medicine 52 (March 2004): S381. http://dx.doi.org/10.1097/00042871-200403002-00102.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Metz, C. N., L. Hallihan, R. Wittenstein, and P. K. Gregersen. "Collection of De-Identified Human Biological Specimens for Research." Journal of Investigative Medicine 52, no. 2_suppl_part_2 (2004): 381. http://dx.doi.org/10.1177/108155890405202s102.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Lewis, Michelle Huckaby. "Laboratory Specimens and Genetic Privacy: Evolution of Legal Theory." Journal of Law, Medicine & Ethics 41, S1 (2013): 65–68. http://dx.doi.org/10.1111/jlme.12042.

Full text
Abstract:
Human biological tissue samples are an invaluable resource for biomedical research designed to find causes of diseases and their treatments. Controversy has arisen, however, when research has been conducted with laboratory specimens either without the consent of the source of the specimen or when the research conducted with the specimen has expanded beyond the scope of the original consent agreement. Moreover, disputes have arisen regarding which party, the researcher or the source of the specimen, has control over who may use the specimens and for what purposes. The purposes of this article a
APA, Harvard, Vancouver, ISO, and other styles
6

Jani, Musfiroh Binti, and Shafiqah Shahirah Mohammad Zakaria. "Determination of Formaldehyde from Disposal of Formaldehyde Fixed Biological Specimen Buried in Soil." Sains Malaysiana 50, no. 8 (2021): 2241–49. http://dx.doi.org/10.17576/jsm-2021-5008-09.

Full text
Abstract:
Biomedical waste specifically anatomical specimens and body parts will be incinerated by a local incineration facility. However, the incineration of formaldehyde fixed specimen from hospitals poses hazardous effect to human and environment due to an exposure of highly toxic gases such as dioxins and furans. In addition, this practise is considered as non-shariah compliance by Muslim community. Thus, a safer and shariah-compliance option to dispose anatomical specimens through deep burial has been introduced. The concern has been raised on the side effect of the formaldehyde treated specimen to
APA, Harvard, Vancouver, ISO, and other styles
7

Margalho, Cláudia, Francisco Corte-Real, Manuel López-Rivadulla, and Eugenia Gallardo. "Salvia divinorum: toxicological aspects and analysis in human biological specimens." Bioanalysis 8, no. 13 (2016): 1415–25. http://dx.doi.org/10.4155/bio-2016-0067.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Metz, C. N., L. Hallihan, R. Wittenstein, and P. K. Gregersen. "28 COLLECTION OF DE-IDENTIFIED HUMAN BIOLOGICAL SPECIMENS FOR RESEARCH." Journal of Investigative Medicine 52, Suppl 2 (2004): S381.5—S381. http://dx.doi.org/10.1136/jim-52-suppl2-102.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Lipka, J. J., J. F. Hainfeld, and J. S. Wall. "Heavy Atom Cluster Labeling of Biological Specimens." Proceedings, annual meeting, Electron Microscopy Society of America 43 (August 1985): 718–19. http://dx.doi.org/10.1017/s042482010012028x.

Full text
Abstract:
The Brookhaven STEM is capable of resolving single heavy atoms deposited on thin carbon films with a beam dose > 103 el Å-2 Single heavy atoms, therefore, are unsuitable as fiducial markers on unordered biological specimens because of the high beam dose required for direct visualization. Heavy metal-clusters or heavy metal-containing complexes have been resolved at much lower beam doses, as low as 30 el Å-2, and therefore may be useful as directly visible labels.The polyamine undecagold (11-Au) cluster ion, [(p-H2NCH2C6H4)3P]7 Au113+, has been used to covalently label the carbohydrate sites
APA, Harvard, Vancouver, ISO, and other styles
10

Antunes, Mónica, Mário Barroso, and Eugenia Gallardo. "Analysis of Cannabinoids in Biological Specimens: An Update." International Journal of Environmental Research and Public Health 20, no. 3 (2023): 2312. http://dx.doi.org/10.3390/ijerph20032312.

Full text
Abstract:
Cannabinoids are still the most consumed drugs of abuse worldwide. Despite being considered less harmful to human health, particularly if compared with opiates or cocaine, cannabis consumption has important medico-legal and public health consequences. For this reason, the development and optimization of sensitive analytical methods that allow the determination of these compounds in different biological specimens is important, involving relevant efforts from laboratories. This paper will discuss cannabis consumption; toxicokinetics, the most detected compounds in biological samples; and charact
APA, Harvard, Vancouver, ISO, and other styles
11

Trang, Nguyen Thi Thu, Jungshan Chang, Wei-An Chen, et al. "A Novel Microchip Technique for Quickly Identifying Nanogranules in an Aqueous Solution by Transmission Electron Microscopy: Imaging of Platelet Granules." Applied Sciences 10, no. 14 (2020): 4946. http://dx.doi.org/10.3390/app10144946.

Full text
Abstract:
Ultrastructural observation of biological specimens or nanogranules usually requires the use of electron microscopy. Electron microscopy takes a lot of time, requires many steps, and uses many chemicals, which may affect the native state of biological specimens. A novel microchip (K-kit) was used as a specimen kit for in situ imaging of human platelet granules in an aqueous solution using a transmission electron microscope. This microchip enabled us to observe the native human platelet granules very quickly and easily. The protocols included blood collection, platelet purification, platelet gr
APA, Harvard, Vancouver, ISO, and other styles
12

Elliott, Marina, and Mark Collard. "F ordisc and the determination of ancestry from cranial measurements." Biology Letters 5, no. 6 (2009): 849–52. http://dx.doi.org/10.1098/rsbl.2009.0462.

Full text
Abstract:
Determining the ancestry of unidentified human remains is a major task for bioarchaeologists and forensic anthropologists. Here, we report an assessment of the computer program that has become the main tool for accomplishing this task. Called F ordisc , the program determines ancestry through discriminant function analysis of cranial measurements. We evaluated the utility of F ordisc with 200 specimens of known ancestry. We ran the analyses with and without the test specimen's source population included in the program's reference sample, and with and without specifying the sex of the test spec
APA, Harvard, Vancouver, ISO, and other styles
13

Kurz, Sascha, Marc Gebhardt, Fanny Grundmann, Christoph-Eckhard Heyde, and Hanno Steinke. "Approach to standardized material characterization of the human lumbopelvic system—Specification, preparation and storage." PLOS ONE 18, no. 8 (2023): e0289482. http://dx.doi.org/10.1371/journal.pone.0289482.

Full text
Abstract:
The complexity of the osseo-ligamentous lumbopelvic system has made it difficult to perform both, the overall preparation as well as specimen harvesting and material testing with a reasonable amount of time and personnel. The logistics of such studies present a hurdle for reproducibility. A structured procedure was developed and proved, which allows all necessary steps to be carried out reproducibly and in a reasonable time. This enables the extraction of 26 soft tissue, 33 trabecular and 32 cortical bone specimens from this anatomical region per cadaver. The integrity of the specimens remains
APA, Harvard, Vancouver, ISO, and other styles
14

Hortolà, Policarp. "Human Bloodstains on Biological Materials: High-Vacuum Scanning Electron Microscope Examination Using Specimens without Previous Preparation." Microscopy and Microanalysis 19, no. 2 (2013): 415–19. http://dx.doi.org/10.1017/s1431927612014183.

Full text
Abstract:
AbstractStudies of human bloodstains on nonbiological materials have been previously carried out using a high-vacuum scanning electron microscope (HV-SEM) in secondary-electron mode without any sample treatment. To assess whether biological substrates can affect the morphology of human erythrocytes in bloodstains, three fragments of different biological material (bone, shell, and wood) were smeared with peripheral human blood. Afterward, the bloodstains were directly examined in secondary-electron mode by an HV-SEM following a procedure initially standardized to be used in uncoated human blood
APA, Harvard, Vancouver, ISO, and other styles
15

Heffernan, Amy L., Lesa L. Aylward, Leisa-Maree L. Toms, Peter D. Sly, Matthew Macleod, and Jochen F. Mueller. "Pooled biological specimens for human biomonitoring of environmental chemicals: Opportunities and limitations." Journal of Exposure Science & Environmental Epidemiology 24, no. 3 (2013): 225–32. http://dx.doi.org/10.1038/jes.2013.76.

Full text
APA, Harvard, Vancouver, ISO, and other styles
16

Crowther, R. A. "The Leeuwenhoek lecture 2006. Microscopy goes cold: frozen viruses reveal their structural secrets." Philosophical Transactions of the Royal Society B: Biological Sciences 363, no. 1502 (2007): 2441–51. http://dx.doi.org/10.1098/rstb.2007.2150.

Full text
Abstract:
The electron microscope provides a powerful tool for investigating the structure of biological complexes such as viruses. A modern instrument is fully capable of atomic resolution on suitable non-biological specimens, but biological materials are difficult to preserve, owing to their fragility, and to image, owing to their radiation, sensitivity. The act of imaging the specimen severely damages it. Originally, samples were prepared by staining with a heavy metal salt, which provides a stable specimen but limits the amount of details that can be retrieved. Now particulate specimens, such as vir
APA, Harvard, Vancouver, ISO, and other styles
17

Paul, Subhra Kumar. "Head Space-GC Analysis of N, N-Diethyl-M-Toluamide (DEET) in Human Postmortem Specimens: A Forensic Case Report." International Journal of Forensic Sciences 8, no. 3 (2023): 1–4. http://dx.doi.org/10.23880/ijfsc-16000325.

Full text
Abstract:
In India, self-poisoning through pesticides is an increasingly common form of suicide. Although deleterious insect repellents (sub-classification of pesticides) are regulated or interdicted, but significant data related to misuse can be procured. Meanwhile, the emergence of novel commercially manufactured products containing insect repellant as a prime ingredient without public and scientific apprehension regarding detrimental impacts has exacerbated the circumstances. Forensic examination of the viscera of the deceased discerned that the death was attributable to Diethyltoulamide intoxication
APA, Harvard, Vancouver, ISO, and other styles
18

Rominiyi, Ola, Katie Myers, Aurelie Vanderlinden, et al. "TMOD-39. EX-VIVO 3-DIMENSIONAL MODELS OF POST-SURGICAL RESIDUAL DISEASE IN HUMAN GLIOBLASTOMA." Neuro-Oncology 21, Supplement_6 (2019): vi271. http://dx.doi.org/10.1093/neuonc/noz175.1138.

Full text
Abstract:
Abstract Translation of novel therapies for glioblastoma from laboratory to clinical trials has relied heavily on cells derived from within patient tumours. However, it is clear from over 40 years of limited improvement in survival rates, that the traditional paradigm of 2-dimensional in-vitro studies using these cells followed by implantation into mouse models poorly predicts the treatment response of glioblastoma cells left behind after surgery in patients. Additionally, recent increases in the number of new therapies requiring pre-clinical evaluation emphasise a need to apply disease models
APA, Harvard, Vancouver, ISO, and other styles
19

Rui, Zhang, Chen Wei Ling, Huang Xing Yun, et al. "New methods of mold control in animal specimens." SDRP Journal of Earth Sciences & Environmental Studies 5, no. 1 (2020): 35–43. http://dx.doi.org/10.25177/jeses.5.1.ra.10629.

Full text
Abstract:
Mold spores and hyphae infection is a serious problem and can lead to damage or loss of natural history specimens. Animal specimens play an important role in cultural exchange, science popularization, scientific research and economic window, but the preparation and preservation technology system of biological specimens is relatively unsafe and inefficient. Infection by Mold spores and hyphae is not only an acute problem that may cause damage or loss of specimens,but alsois very harmful to human beings health and polluted to environment, It is one of the principal element that restricts the dev
APA, Harvard, Vancouver, ISO, and other styles
20

Granados Mendoza, Carolina, Miguel Murguía-Romero, and Gerardo A. Salazar. "It’s time to celebrate! Linking genetic resources to the Mexican National Biological Collections custodied by the Institute of Biology of the National Autonomous University of Mexico." Revista Mexicana de Biodiversidad 95 (October 9, 2024): e955509. http://dx.doi.org/10.22201/ib.20078706e.2024.95.5509.

Full text
Abstract:
The Instituto de Biología of the Universidad Nacional Autónoma de México (IBUNAM) celebrates 95 years as a leading institution on biodiversity research. Besides developing frontier research, training of human resources, and public science communication, IBUNAM houses 10 National Zoological Collections and the National Herbarium of Mexico (MEXU). The specimens deposited in these collections are the foundation of numerous biological studies, from which ample genetic resources have been generated. Here we present an initial effort to link the specimens deposited at the National Biological Collect
APA, Harvard, Vancouver, ISO, and other styles
21

Sotgia, Salvatore, Arduino Mangoni, Mauro Forteschi, et al. "Identification of the Main Intermediate Precursor of l-Ergothioneine Biosynthesis in Human Biological Specimens." Molecules 21, no. 10 (2016): 1298. http://dx.doi.org/10.3390/molecules21101298.

Full text
APA, Harvard, Vancouver, ISO, and other styles
22

Elmgren, Lindsay D., Susan A. Nadin-Davis, Frances T. Muldoon, and Alexander I. Wandeler. "Diagnosis and Analysis of a Recent Case of Human Rabies in Canada." Canadian Journal of Infectious Diseases 13, no. 2 (2002): 129–33. http://dx.doi.org/10.1155/2002/235073.

Full text
Abstract:
BACKGROUND: On September 30, 2000, staff at the Canadian Food Inspection Agency's Centre of Expertise for Rabies, located at the Animal Diseases Research Institute in Ottawa, Ontario, diagnosed rabies in a child from Quebec. This was the first case of rabies in a human in Canada in 15 years and in 36 years in the province of Quebec. After spending a week in intensive care in a Montreal hospital, the nine-year-old boy succumbed to this nearly always fatal disease. The boy had been exposed to a bat in late August 2000, while vacationing with his family in the Quebec countryside.METHODS: Antemort
APA, Harvard, Vancouver, ISO, and other styles
23

Mitchell, Kaitlin F., Carey-Ann D. Burnham, and Ann M. Gronowski. "Urinary Tract Infection With Gram-Positive Bacteria Does Not Cause False-Positive Results with the Urine-Based Human Chorionic Gonadotropic Point-of-Care Assay." Journal of Applied Laboratory Medicine 5, no. 5 (2020): 987–92. http://dx.doi.org/10.1093/jalm/jfaa056.

Full text
Abstract:
Abstract Background False-positive results for human chorionic gonadotropic (hCG) on point-of-care (POC) devices can occur for a variety of technical and biological reasons. It has been postulated that urinary tract infection can result in false-positive POC hCG assays, but the cause of this phenomenon remains elusive. Gram-positive bacteria have previously been reported to express an hCG-like molecule. We investigated whether urinary tract infection with Gram-positive bacteria can result in false-positive POC hCG. Methods We utilized remnant clinical urine specimens that had been submitted fo
APA, Harvard, Vancouver, ISO, and other styles
24

Tangerman, Albert. "Highly sensitive gas chromatographic analysis of ethanol in whole blood, serum, urine, and fecal supernatants by the direct injection method." Clinical Chemistry 43, no. 6 (1997): 1003–9. http://dx.doi.org/10.1093/clinchem/43.6.1003.

Full text
Abstract:
Abstract A highly sensitive, reproducible, and rapid gas chromatographic method for ethanol determination in various biological specimens (human whole blood, serum, urine, and fecal supernatants) was developed. The method involves direct injection of the biological specimen into the gas chromatograph, without any pretreatment. Contamination of the gas chromatographic column with nonvolatile material was prevented by the use of a glass liner in the injector. This liner, which acted as a precolumn, was partly filled with small glass beads. Injection was performed in between the glass beads. More
APA, Harvard, Vancouver, ISO, and other styles
25

Taneda, S., and V. M. Monnier. "ELISA of pentosidine, an advanced glycation end product, in biological specimens." Clinical Chemistry 40, no. 9 (1994): 1766–73. http://dx.doi.org/10.1093/clinchem/40.9.1766.

Full text
Abstract:
Abstract Pentosidine is a fluorescent protein cross-link and glycoxidation marker for the advanced glycation reaction in diabetes, aging, and uremia. We raised polyclonal antibodies in New Zealand White rabbits against this hapten coupled to keyhole limpet hemocyanin. The antibodies detected by ELISA reacted strongly with free pentosidine but not with pentosidine-like compounds. The working range of the competitive ELISA for standard pentosidine was 0.1-100 pmol. Pentosidine was detectable in bovine serum albumin incubated with ribose as a function of incubation time. Immunoblotting studies sh
APA, Harvard, Vancouver, ISO, and other styles
26

Zahira, Farah, Kusuma Scorpia Lestari, and Ahmad Zaharin Aris. "Determinants of Persistent Organic Pollutants (POPs) Levels in Human Specimens: A Review." JURNAL KESEHATAN LINGKUNGAN 13, no. 4 (2021): 227. http://dx.doi.org/10.20473/jkl.v13i4.2021.227-240.

Full text
Abstract:
Introduction: Numerous studies have been conducted regarding persistent organic pollutants (POPs) concentrations in human biological matrices such as blood, breast milk, urine, and hair that cause adverse health effects such as breast cancer, cardiovascular diseases, and type 2 diabetes. This study aimed to determine the POPs presence in human specimens in household settings. Discussion: A total of 28 articles were included in this study with the criteria published in 2016- 2021, original research articles, free full text available, and studied at least one of the confounding variables of POPs
APA, Harvard, Vancouver, ISO, and other styles
27

Krotulski, Alex J., Donna M. Papsun, Bruno S. De Martinis, Amanda L. A. Mohr, and Barry K. Logan. "N-Ethyl Pentylone (Ephylone) Intoxications: Quantitative Confirmation and Metabolite Identification in Authentic Human Biological Specimens." Journal of Analytical Toxicology 42, no. 7 (2018): 467–75. http://dx.doi.org/10.1093/jat/bky025.

Full text
APA, Harvard, Vancouver, ISO, and other styles
28

Kontonasaki, Eleana, A. Sivropoulou, Lambrini Papadopoulou, P. Garefis, Konstantinos M. Paraskevopoulos, and Petros Koidis. "Attachment and Proliferation of Human Periodontal Ligament Fibroblasts on Fibronectin-Coated Bioactive Glass Modified Ceramics." Key Engineering Materials 309-311 (May 2006): 727–30. http://dx.doi.org/10.4028/www.scientific.net/kem.309-311.727.

Full text
Abstract:
The effect of fibronectin (FN) on human periodontal ligament fibroblasts (PDLF) attachment and proliferation on Bioglass® (PerioGlas® Synthetic Bone Graft Particulate, US Biomaterials) modified dental ceramics, was investigated in vitro. FN introduced limited alterations in cell attachment on Bioglass®-modified dental ceramics in comparison with the corresponding non-FN-coated specimens but had a profound positive effect on Bioglass®-coated specimens that weakly supported both cell attachment and proliferation. The amount of protein adsorbed on the specimens was not proportional to its biologi
APA, Harvard, Vancouver, ISO, and other styles
29

SANO, Toshikazu, Gen HIRASAWA, Junji TAKEYAMA та ін. "17β-Hydroxysteroid dehydrogenase type 2 expression and enzyme activity in the human gastrointestinal tract". Clinical Science 101, № 5 (2001): 485–91. http://dx.doi.org/10.1042/cs1010485.

Full text
Abstract:
The 17β-hydroxysteroid dehydrogenases (17βHSDs) play an important role in the regulation of intracellular levels of biologically active sex steroid hormones in various human tissues. To date, eight distinctive 17βHSD enzymes have been cloned and characterized in humans. Among these isoenzymes, 17βHSD type 2 (17βHSD2) catalyses the conversion of testosterone into androstenedione and/or oestradiol into oestrone in various tissues, and it has thus been suggested to be involved in the biological inactivation of these sex steroids. The human gastrointestinal tract and liver are considered as the pr
APA, Harvard, Vancouver, ISO, and other styles
30

Fujita, Hideaki, and Tomonobu M. Watanabe. "Use of optical techniques to evaluate the ionizing radiation effects on biological specimens." Journal of Radiation Research 65, Supplement_1 (2024): i117—i125. https://doi.org/10.1093/jrr/rrae016.

Full text
Abstract:
Abstract Radiation induces various changes in biological specimens; however, the evaluation of these changes is usually complicated and can be achieved only through investment in time and labor. Optical methods reduce the cost of such evaluations as they require less pretreatment of the sample, are adaptable to high-throughput screening and are easy to automate. Optical methods are also advantageous, owing to their real-time and onsite evaluation capabilities. Here, we discuss three optical technologies to evaluate the effects of radiation on biological samples: single-molecule tracking micros
APA, Harvard, Vancouver, ISO, and other styles
31

Sass, Jan-Oliver, Marie-Luise Sellin, Elisa Kauertz, et al. "Advanced Ti–Nb–Ta Alloys for Bone Implants with Improved Functionality." Journal of Functional Biomaterials 15, no. 2 (2024): 46. http://dx.doi.org/10.3390/jfb15020046.

Full text
Abstract:
The additive manufacturing of titanium–niobium–tantalum alloys with nominal chemical compositions Ti–xNb–6Ta (x = 20, 27, 35) by means of laser beam powder bed fusion is reported, and their potential as implant materials is elaborated by mechanical and biological characterization. The properties of dense specimens manufactured in different build orientations and of open porous Ti–20Nb–6Ta specimens are evaluated. Compression tests indicate that strength and elasticity are influenced by the chemical composition and build orientation. The minimum elasticity is always observed in the 90° orientat
APA, Harvard, Vancouver, ISO, and other styles
32

Wang, Zhi-wen, Li-jun Zhang, Yu Zhuang, Zhi-fen Lv, and Zhi-ming Tan. "CKS2 and S100A12: Two Novel Diagnostic Biomarkers for Rheumatoid Arthritis." Disease Markers 2022 (June 25, 2022): 1–9. http://dx.doi.org/10.1155/2022/2431976.

Full text
Abstract:
Rheumatoid arthritis (RA) is a chronic systematicness autoimmunity disease with joint inflammation. RA etiology is still unknown. Early and exact diagnosing is still hard to reach. In the paper, we purposed to discover novel diagnosis biological marker for RA. Two open, usable gene expression profiles of human RA as well as controlled specimens (dataset GSE17755 as well as GSE93272) were downloaded from the GEO database. Differentially expressed genes (DEGs) were screened between 331 RA and 88 control samples. Functional enrichment analysis was applied to explore the possible function of DEGs.
APA, Harvard, Vancouver, ISO, and other styles
33

Jung, Yoonsun, Ji-Young Yoon, Kapil Dev Patel, et al. "Biological Effects of Tricalcium Silicate Nanoparticle-Containing Cement on Stem Cells from Human Exfoliated Deciduous Teeth." Nanomaterials 10, no. 7 (2020): 1373. http://dx.doi.org/10.3390/nano10071373.

Full text
Abstract:
Nanomaterials can enhance interactions with stem cells for tissue regeneration. This study aimed to investigate the biological effects of tricalcium silicate nanoparticle-containing cement (Biodentine™) during or after setting on stem cells from human exfoliated deciduous teeth (SHED) to mimic clinically relevant situations in which materials are adapted. Specimens were divided into four groups depending on the start of extraction time (during (3, 6 and 12 min) or after setting (24 h)) and extracted in culture medium for 24 h for further physicochemical and biological analysis. After cell viab
APA, Harvard, Vancouver, ISO, and other styles
34

Kwon, Soonwook, Se-Bum Choi, Min Gyu Park, Hyunung Yu, Seung-Woo Suh, and Im Joo Rhyu. "Extraction of Three-Dimensional Information of Biological Membranous Tissue with Scanning Confocal Infrared Laser Microscope Tomography." Microscopy and Microanalysis 19, S5 (2013): 194–97. http://dx.doi.org/10.1017/s1431927613012646.

Full text
Abstract:
AbstractThe “LEXT” confocal laser scanning microscope has been used for the three-dimensional (3D) imaging of the surface of specimens, especially in materials science fields, by the penetration of near-infrared (NIR) light without mechanical cutting, deposition, or other specimen pretreatment. Noninvasive investigation of various biological tissues such as human spinal dura mater, rat aorta, and cornea without the dehydration process was successfully carried out with the “LEXT,” in order to access both surface and internal topographic images of the biological structures at a good status of th
APA, Harvard, Vancouver, ISO, and other styles
35

Muhayudin, N. A., K. S. Basaruddin, H. Yazid, and A. F. Salleh. "Development of Synthetic Spine for Biomechanical Research: An Overview." Journal of Physics: Conference Series 2051, no. 1 (2021): 012072. http://dx.doi.org/10.1088/1742-6596/2051/1/012072.

Full text
Abstract:
Abstract Human and animal cadaveric spines are the most common specimens used in biomechanical investigations. However, biological cadaveric spines come with a lot of disadvantages, which resulted in questionable reliability of the data obtained. This motivated the authors to look at the development of a working synthetic spine in motion segments because synthetic materials have been used widely to replace the cadaveric specimens especially for bone testing. The objective of this paper is to provide an overview of the current development of a working synthetic spine and why it is crucial to co
APA, Harvard, Vancouver, ISO, and other styles
36

Winfield, S. A., N. D. Boyd, M. J. Vimy, and F. L. Lorscheider. "Measurement of total mercury in biological specimens by cold vapor atomic fluorescence spectrometry." Clinical Chemistry 40, no. 2 (1994): 206–10. http://dx.doi.org/10.1093/clinchem/40.2.206.

Full text
Abstract:
Abstract An ultrasensitive method for determining total mercury concentrations in biological specimens is a prerequisite for monitoring exposure to chronic low-dose levels of Hg vapor such as those from dental silver amalgam fillings. The clinical consequences of such doses are currently in question. We describe an adaptation of a two-stage gold amalgamation preconcentration step combined with cold vapor atomic fluorescence spectrometric detection for Hg. At Hg concentrations of 40 and 350 nmol/L, the within-day assay CVs were 5% and 3%, respectively; between-day assay CVs were 8% and 5%, resp
APA, Harvard, Vancouver, ISO, and other styles
37

Kirchman, Jeremy J., Christopher C. Witt, Jimmy A. McGuire, and Gary R. Graves. "DNA from a 100-year-old holotype confirms the validity of a potentially extinct hummingbird species." Biology Letters 6, no. 1 (2009): 112–15. http://dx.doi.org/10.1098/rsbl.2009.0545.

Full text
Abstract:
We used mtDNA sequence data to confirm that the controversial 100-year-old holotype of the Bogotá sunangel ( Heliangelus zusii ) represents a valid species. We demonstrate that H. zusii is genetically well differentiated from taxa previously hypothesized to have given rise to the specimen via hybridization. Phylogenetic analyses place H. zusii as sister to a clade of mid- to high-elevation Andean species currently placed in the genera Taphrolesbia and Aglaiocercus. Heliangelus zusii , presumed extinct, has never been observed in nature by biologists. We infer that the species occupied a restri
APA, Harvard, Vancouver, ISO, and other styles
38

Hofstetter, Jessica N., Fernanda S. Nascimento, Subin Park, et al. "Evaluation of Multilocus Sequence Typing of Cyclospora cayetanensis based on microsatellite markers." Parasite 26 (2019): 3. http://dx.doi.org/10.1051/parasite/2019004.

Full text
Abstract:
Cyclospora cayetanensis is a human parasite transmitted via ingestion of contaminated food or water. Cases of C. cayetanensis infection acquired in the United States often go unexplained, partly because of the difficulties associated with epidemiologic investigations of such cases and the lack of genotyping methods. A Multilocus Sequence Typing (MLST) method for C. cayetanensis based on five microsatellite loci amplified by nested PCR was described in 2016. The MLST loci had high variability, but many specimens could not be assigned a type because of poor DNA sequencing quality at one or more
APA, Harvard, Vancouver, ISO, and other styles
39

Laitinen, Liisa, Harri Juusela, and Ismo Virtanen. "Binding of the blood group-reactive lectins to human adult kidney specimens." Anatomical Record 226, no. 1 (1990): 10–17. http://dx.doi.org/10.1002/ar.1092260103.

Full text
APA, Harvard, Vancouver, ISO, and other styles
40

Kusano, Maiko, Eladio Mendez, and Kenneth G. Furton. "Development of headspace SPME method for analysis of volatile organic compounds present in human biological specimens." Analytical and Bioanalytical Chemistry 400, no. 7 (2011): 1817–26. http://dx.doi.org/10.1007/s00216-011-4950-2.

Full text
APA, Harvard, Vancouver, ISO, and other styles
41

Little, M., A. Tripathi, and F. Barchi. "Collection and use of human biological specimens in research: Is there adequate ethics governance in Africa?" Annals of Global Health 81, no. 1 (2015): 68. http://dx.doi.org/10.1016/j.aogh.2015.02.662.

Full text
APA, Harvard, Vancouver, ISO, and other styles
42

González-Alonso, Mónica, Jaime Ulayar-Arroyo, and Arturo H. Ariño. "When Specimens Become Environmental Traits: Automating data extraction in aerobiology." Biodiversity Information Science and Standards 6 (September 15, 2022): e94914. https://doi.org/10.3897/biss.6.94914.

Full text
Abstract:
The identity of a biological specimen can be considered the most basic type of trait: the species (or higher taxon) the specimen belongs to, one of the three most fundamental data elements (along with location and time) that configure the primary biodiversity data record whose quantification may underpin biological monitoring programs. A general image containing specimens (for example, a photo from a surveillance camera), where individual organisms are to be identified, is akin to an image of a single organism where traits are to be recognized: the individual, often distinct organisms in the i
APA, Harvard, Vancouver, ISO, and other styles
43

He, Yichen, Christopher R. Cooney, Steve Maddock, and Gavin H. Thomas. "Using pose estimation to identify regions and points on natural history specimens." PLOS Computational Biology 19, no. 2 (2023): e1010933. http://dx.doi.org/10.1371/journal.pcbi.1010933.

Full text
Abstract:
A key challenge in mobilising growing numbers of digitised biological specimens for scientific research is finding high-throughput methods to extract phenotypic measurements on these datasets. In this paper, we test a pose estimation approach based on Deep Learning capable of accurately placing point labels to identify key locations on specimen images. We then apply the approach to two distinct challenges that each requires identification of key features in a 2D image: (i) identifying body region-specific plumage colouration on avian specimens and (ii) measuring morphometric shape variation in
APA, Harvard, Vancouver, ISO, and other styles
44

Helft, Paul R., Victoria L. Champion, Rachael Eckles, Cynthia S. Johnson, and Eric M. Meslin. "Cancer Patients' Attitudes toward Future Research Uses of Stored Human Biological Materials." Journal of Empirical Research on Human Research Ethics 2, no. 3 (2007): 15–22. http://dx.doi.org/10.1525/jer.2007.2.3.15.

Full text
Abstract:
The policy debate concerning informed consent for future, unspecified research of stored human biological materials (HBM) would benefit from an understanding of the attitudes of individuals who contribute tissue specimens to HBM repositories. Cancer patients who contributed leftover tissue to the Indiana University Cancer Center Tissue Bank under such conditions were recruited for a mail survey study of their attitudes. Our findings suggest that a clear majority of subjects would permit unlimited future research on stored HBMs without re-contact and re-consent, and a significant minority appea
APA, Harvard, Vancouver, ISO, and other styles
45

Mesiwala, Ali H., Louis D. Scampavia, Peter S. Rabinovitch, Jaromir Ruzicka, and Robert C. Rostomily. "On-line Flow Cytometry for Real-time Surgical Guidance." Neurosurgery 55, no. 3 (2004): 551–61. http://dx.doi.org/10.1227/01.neu.0000134470.13971.0c.

Full text
Abstract:
Abstract OBJECTIVE: This study tests the feasibility of using on-line analysis of tissue during surgical resection of brain tumors to provide biologically relevant information in a clinically relevant time frame to augment surgical decision making. For the purposes of establishing feasibility, we used measurement of deoxyribonucleic acid (DNA) content as the end point for analysis. METHODS: We investigated the feasibility of interfacing an ultrasonic aspiration (USA) system with a flow cytometer (FC) capable of analyzing DNA content (DNA-FC). The sampling system design, tissue preparation requ
APA, Harvard, Vancouver, ISO, and other styles
46

Oliveira, Ana Elisa F., Arnaldo César Pereira, Mayra A. C. Resende, and Lucas Franco Ferreira. "Disposable Voltammetric Immunosensor for Determination and Quantification of Biomarker CA 15-3 in Biological Specimens." Analytica 5, no. 1 (2024): 74–89. http://dx.doi.org/10.3390/analytica5010005.

Full text
Abstract:
A disposable voltammetric immunosensor was developed to measure breast cancer biomarker 15-3 (CA 15-3) in human saliva and serum samples. Screen-printed paper-based electrodes (f-SPE) previously fabricated by our research group using homemade conductive inks were used as transducers, which were later modified only with gold nanoparticles to immobilize anti-CA 15-3 antibodies. The sensor was operated using antigen–antibody interactions in conjunction with a redox species (ferrocyanide potassium) for the indirect determination of the CA 15-3 antigen. The device characterization involved atomic f
APA, Harvard, Vancouver, ISO, and other styles
47

Muccioli, G., C. Ghè, G. Faccani, M. Lanotte, M. Forni, and E. Ciccarelli. "Prolactin receptors in human meningiomas: characterization and biological role." Journal of Endocrinology 153, no. 3 (1997): 365–71. http://dx.doi.org/10.1677/joe.0.1530365.

Full text
Abstract:
Abstract Sixty cerebral meningioma specimens obtained at surgery from 34 female and 26 male patients were examined for the presence of prolactin (PRL) receptors. These were compared with normal arachnoid tissue from which these tumours arise. PRL receptors were detected in 61·7% of meningiomas whereas no PRL binding was found in samples of normal arachnoid tissue. No relationship was found when sex or histological findings were compared with the presence of PRL receptors. Receptor-positive tumours had saturable and high-affinity (Kd, 4·8 ± 0·5 ng/ml) receptors with hormonal specificity for hum
APA, Harvard, Vancouver, ISO, and other styles
48

Kinloch, Natalie N., Gordon Ritchie, Chanson J. Brumme, et al. "Suboptimal Biological Sampling as a Probable Cause of False-Negative COVID-19 Diagnostic Test Results." Journal of Infectious Diseases 222, no. 6 (2020): 899–902. http://dx.doi.org/10.1093/infdis/jiaa370.

Full text
Abstract:
Abstract False-negative severe acute respiratory syndrome coronavirus 2 test results can negatively impact the clinical and public health response to coronavirus disease 2019 (COVID-19). We used droplet digital polymerase chain reaction (ddPCR) to demonstrate that human DNA levels, a stable molecular marker of sampling quality, were significantly lower in samples from 40 confirmed or suspected COVID-19 cases that yielded negative diagnostic test results (ie, suspected false-negative test results) compared with a representative pool of 87 specimens submitted for COVID-19 testing. Our results su
APA, Harvard, Vancouver, ISO, and other styles
49

Chen, Libo, Ruizhi Wang, Ligui Gao, and Wei Shi. "Opa-Interacting Protein 5 Expression in Human Glioma Tissues Is Essential to the Biological Function of U251 Human Malignant Glioma Cells." Cancer Control 27, no. 1 (2020): 107327482096891. http://dx.doi.org/10.1177/1073274820968914.

Full text
Abstract:
Opa-interacting protein 5 (OIP5) is a member of the cancer-testis antigen (CTA) family that elicits a spontaneous antitumor immune response. The failure of current immunotherapies for glioma has prompted the search for novel biomarkers that may be utilized as therapeutic targets. This study aimed to investigate whether OIP5 serves as a target for malignant glioma immunotherapy. Glioma specimens from 53 adult patients were evaluated for OIP5 expression by immunohistochemical (IHC) staining, and the correlation of OIP5 expression with World Health Organization (WHO) tumor grade was analyzed. End
APA, Harvard, Vancouver, ISO, and other styles
50

Li, Qiling, Ting Kang, Xiaohua Tian, et al. "Multimeric Stability of Human C-reactive Protein in Archived Specimens." PLoS ONE 8, no. 3 (2013): e58094. http://dx.doi.org/10.1371/journal.pone.0058094.

Full text
APA, Harvard, Vancouver, ISO, and other styles
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!