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Dissertations / Theses on the topic 'Human genetics – Research – Australia'

Author: Grafiati

Published: 10 December 2022

Last updated: 19 July 2025

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1

Hallam, Adrienne Louise. "Globalisation, Human Genomic Research and the Shaping of Health: An Australian Perspective." Thesis, Griffith University, 2003. http://hdl.handle.net/10072/367541.

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This thesis examines one of the premier "big science" projects of the contemporary era - the globalised genetic mapping and sequencing initiative known as the Human Genome Project (HGP), and how Australia has responded to it. The study focuses on the relationship between the HGP, the biomedical model of health, and globalisation. It seeks to examine the ways in which the HGP shapes ways of thinking about health; the influence globalisation has on this process; and the implications of this for smaller nations such as Australia. Adopting a critical perspective grounded in political economy, t

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2

Hawkins, Naomi. "Human gene patents and translational research in genetics." Thesis, University of Oxford, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.527328.

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3

Webb, Sim F. "Cell culture of human lens epithelia in cataract research." Thesis, University of East Anglia, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.320778.

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4

Figueira, Edwin C. Medical Sciences Faculty of Medicine UNSW. "???Stem Cell Pathway??? gene expression in human foetal limbus and cadaveric human limbal epithelium." Awarded by:University of New South Wales. School of Medical Sciences, 2006. http://handle.unsw.edu.au/1959.4/27455.

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Stem cells play a vital role in the turn over of permanently self-renewing tissues (e.g. corneal epithelium, epidermis, bone marrow). Stratified cornea epithelia serve, as ideal tissue models for studying ???stemness???, as the site of cells in the different stages of differentiation are anatomically easily identifiable. Studies targeting limbal stem cell maintenance, in-vitro gene expression during storage and differentiation will benefit future therapeutic applications (e.g. corneal transplantation). Knowledge of stem cell behaviour will help explain the pathophysiology of corneal related oc

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5

Goike, Helena M. "Genetic analysis of human astrocytic gliomas : xenografts as a research tool /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3805-9/.

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6

Bergström, Anders. "Genomic insights into the human population history of Australia and New Guinea." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/273775.

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The ancient continent of Sahul, encompassing Australia, New Guinea and Tasmania, contains some of the earliest archaeological evidence for humans outside of Africa, dating back to at least 50 thousand years ago (kya). New Guinea was also one of the sites were humans developed agriculture in the last 10 thousand years. Despite the importance of this part of the world to the history of humanity outside Africa, little is known about the population history of the people living here. In this thesis I present population-genetic studies using whole-genome sequencing and genotype array datasets from m

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7

Macgill, Jennifer. "Conducting suicide research in Australia in relation to the operation of Human Research Ethics Committees." Thesis, University of Ballarat, 2008. http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/39930.

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This thesis began with a research project on suicide that was abandoned after many hurdles were encountered in terms of reaching participants and after various applications to ethics committees. The ultimate research question was then recast as ‘Do Human Research Ethics Committees influence the conduct of suicide research in Australia?’ The conceptual framework for setting up the research was derived from literature on Critical Theory, Feminism and Weberian concepts of power and rationality. Subsidiary questions were then derived from this literature and the starting exemplar case of my own re

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8

Balmer, Brian L. "Mutations in the research system? The Human Genome Mapping Project as science policy." Thesis, University of Sussex, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.358200.

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The way in which scientific research is conceived, organized and practiced in the context of shifting policies and institutional structures is the main focus of this thesis. The empirical component examines the development of the UK Human Genome Mapping Project (HGMP), the British contribution to the international plan to locate all of the genes in the human species. A comparative case-study examines the unsuccessful attem pts by Australian scientists to establish a national genome mapping initiative. Two main sets of research questions are posed. Why was the HGMP set up in the UK at the end o

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9

Bell, Jordana Tzenova. "Epistasis in complex human traits." Thesis, University of Oxford, 2006. http://ora.ox.ac.uk/objects/uuid:547db446-c84c-4a6c-8b5c-ce960f7765c5.

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10

Ward, Stephen James Safety Science Faculty of Science UNSW. "Designers and users: a survey of user research methods employed by Australian industrial designers." Awarded by:University of New South Wales. School of Safety Science, 2006. http://handle.unsw.edu.au/1959.4/26206.

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Designers of mass produced products require knowledge about anticipated users of their designs in order to make reasonable predictions about how users will interact with a product and how that product will satisfy users??? needs. However, there is little reported study of how industrial designers get the information they need about users, or to what extent they adapt and use information available from fields of study such as ergonomics or market research. Study in this area is important, in order to have a knowledge base that will support development of methods and data sources that may help

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11

Bangham, Jenny. "Blood groups and the rise of human genetics in mid-twentieth century Britain." Thesis, University of Cambridge, 2014. https://www.repository.cam.ac.uk/handle/1810/265573.

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This dissertation reconstructs how blood groups were made into pre-eminent objects of human genetic research and powerful markers for producing human biological difference. By tracing the ways in which three British laboratories became international centres for blood-group genetic research, it also offers an expanded history of postwar human genetics. In early 1930s Britain a community of geneticists, including R.A. Fisher and B.S. Haldane, promoted blood groups as having the potential to give the study of human heredity 'a solidly objective foundation, under strict statistical control'. Fishe

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12

Clark, S. A. (Stephanie Ann), University of Western Sydney, of Science Technology and Environment College, and of Science Food and Horticulture School. "Systematics, spatial analysis and conservation genetics of Meridolum corneovirens (Pfeiffer, 1851) and related forms (Gastropoda: Camaenidae) from the Sydney region of Australia." THESIS_CSTE_SFH_Clark_S.xml, 2005. http://handle.uws.edu.au:8081/1959.7/640.

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The purpose of the present study is to examine the genetic and morphological variation found in narrow-range endemic terrestrial invertebrate species at different geographic scales, and the ramifications of this for their systematics, management and conservation. The listed endangered land snail Meridolum corneovirens and several related forms are restricted to the Sydney region, and were used to address the above issues. Morphological, anatomical, allozyme and DNA data were obtained for a total of 77 populations from across the known range of Meridolum. A particular emphasis was placed on the

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13

Liu, Yang. "Data mining methods for single nucleotide polymorphisms analysis in computational biology." HKBU Institutional Repository, 2011. http://repository.hkbu.edu.hk/etd_ra/1287.

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14

Nibbe, Rod K. "Systems Biology of Human Colorectal Cancer." Case Western Reserve University School of Graduate Studies / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=case1264179836.

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15

Piñero, González Janet 1977. "Computational approaches and resources to support translational research in human diseases." Doctoral thesis, Universitat Pompeu Fabra, 2015. http://hdl.handle.net/10803/328417.

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In the last two decades, the volume and variety of biomedical data has dramatically increased. The data is heterogeneous and scattered across many resources. This produces bottlenecks in the analysis and extraction of knowledge from this sea of information. To overcome this hurdle, better catalogs that integrate different data types, offer easy access to users, and support automatic workflows, are needed. With this in mind, we have developed DisGeNET, a discovery platform that contains information on more than 17,000 genes related to over 14,000 diseases. We have used DisGeNET to study the pro

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16

Hallam, Adrienne Louise, and n/a. "Globalisation, Human Genomic Research and the Shaping of Health: An Australian Perspective." Griffith University. School of Science, 2003. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20040812.114745.

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This thesis examines one of the premier "big science" projects of the contemporary era - the globalised genetic mapping and sequencing initiative known as the Human Genome Project (HGP), and how Australia has responded to it. The study focuses on the relationship between the HGP, the biomedical model of health, and globalisation. It seeks to examine the ways in which the HGP shapes ways of thinking about health; the influence globalisation has on this process; and the implications of this for smaller nations such as Australia. Adopting a critical perspective grounded in political economy, t

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17

Kim, Leo Dhohoon. "Visualizing discourses and governance of human embryonic stem cell research in South Korea (in comparison to the UK)." Thesis, University of Sussex, 2016. http://sro.sussex.ac.uk/id/eprint/65434/.

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This thesis investigates how the discourses and governance of human embryonic stem cell (hESC) research operated in South Korea. Comparing South Korea to the UK in three fields (government, newspapers, and public responses) and reflecting scientific misconduct in the South Korean scientists' community, the study tries to identify hidden variables that influenced the national trajectory. To capture dynamic yet underrepresented national and cultural characteristics, the author has analysed microscopic interactions including actors' utterances, media framing, human relations and strategies. By us

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18

Perla, Sravan K. "Epigenetic Regulation of the Human Angiotensinogen by Single Nucleotide Polymorphisms." University of Toledo Health Science Campus / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=mco1544800350207546.

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19

Clark, Stephanie A. "Systematics, spatial analysis and conservation genetics of Meridolum corneovirens (Pfeiffer, 1851) and related forms (Gastropoda: Camaenidae) from the Sydney region of Australia." Thesis, View thesis, 2005. http://handle.uws.edu.au:8081/1959.7/640.

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The purpose of the present study is to examine the genetic and morphological variation found in narrow-range endemic terrestrial invertebrate species at different geographic scales, and the ramifications of this for their systematics, management and conservation. The listed endangered land snail Meridolum corneovirens and several related forms are restricted to the Sydney region, and were used to address the above issues. Morphological, anatomical, allozyme and DNA data were obtained for a total of 77 populations from across the known range of Meridolum. A particular emphasis was placed on the

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20

Windsor, Carol A. "Industry policy, finance and the AIDC : Australia from the 1950s to the 1970s." Thesis, University of Queensland, 2009. http://espace.library.uq.edu.au/view/UQ:189307.

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This thesis, conceived within a Marxist framework, addresses key conceptual issues in the writing and theorising on industry policy in post second world- war Australia. Broadly, the thesis challenges the way that industry policy on the left of politics (reflected in the social democratic and Keynesian positions) has been constructed as a practical, progressive policy agenda. Specifically, the thesis poses a direct challenge to the primacy of the ‘national’ in interpreting the history of industry policy. The challenge is to the proposition that conflicts between national industry and internatio

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21

Chakrabortty, Sharmistha. "SNPs and Indels Analysis in Human Genome using Computer Simulation and Sequencing Data." University of Toledo Health Science Campus / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=mco1501726874739045.

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22

Poon, Martha A. "Of molecules & networks : tracing the connection between the distribution of samples, the production of genetic maps and the valuation of DNA in human genetics research." Thesis, McGill University, 2001. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=29404.

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This thesis takes the DNA molecule and its circulation between scientific researchers as an object of analysis. The study's objective was to investigate the techno-social mechanisms through which certain individual's genetic materials are imputed with research value. Two cases, representing two contrasting kinds of circulation practices, are presented. In the first, DNA samples from families diagnosed with hereditary disorders, which allow researchers a shot at the all-or-nothing game of finding genes, are a protected resource. In the second, the DNA reference panel of the CEPH (Centre d'Etude

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23

Sharafizad, Fleur Yardena. "The careers of female academics in Australia: Inhibitors, bottlenecks, drivers and family outcomes." Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 2020. https://ro.ecu.edu.au/theses/2358.

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The continuing under-representation of female academics in senior classifications at Australian universities is widely acknowledged and documented. It has been proposed that universities fail to take advantage of the leadership skills of female academics, thereby inhibiting their organisation’s competitiveness (Airini et al., 2011). Statistics from the Australian Department of Education and Training (2018) indicate over half of full-time and fractional full-time academics are women, yet female academics constitute only a third of positions above that of Senior Lecturer across Australian univer

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24

Donnelly, Andrew James. "The characterisation of human X-linked polymorphic markers and their use in disease gene localisation and identification /." Title page, table of contents and summary only, 1997. http://web4.library.adelaide.edu.au/theses/09PH/09phd6848.pdf.

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25

Kenyon, Jonathan Dallas. "Loss of Mismatch Repair in the Aging Human Hematopoietic Stem Cell." Case Western Reserve University School of Graduate Studies / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=case1354917428.

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26

Truscott, Keith. "Research problem: What are the differences between Wadjela and Nyungar criteria when assessing organisational effectiveness of non-government human service organisations?" Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 2000. https://ro.ecu.edu.au/theses/1368.

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Wadjela and Nyungar experts (of managerial, administrative, service staff), from the same South-West city location in Western Australia were randomly chosen from the non-government human service field for separate workshops and asked the question “what makes a non-government human service organisation effective?" The purpose was to compare the group consensus answer between the two separate workshop groups. The Nyungars are the Indigenous people in the South-West of Western Australia and the Wadjelas are the Non-Indigenous people living in the same area. The results listed five criteria, in or

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27

Nardone, Beatrice. ""Histopathologic and Immunohistochemical Characterization of Rash to Human Epidermal Growth Factor Receptor 1 (HER1) and HER1/2 Inhibitors in Cancer Patients." Thesis, Universita' degli Studi di Catania, 2011. http://hdl.handle.net/10761/311.

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Introduction: Human epidermal receptor (HER) 1 inhibitors and HER 1/2 inhibitors have shown benefit against a wide range of solid tumors. However, their use is associated with rash in 40-90% of patients, which impacts quality of life and interrupts antineoplastic therapy. The pathologic characteristics of affected skin remain unclear, precluding development of rational therapies. The aim of this study is to evaluate differences in histologic and immunohistochemical (IHC) alterations in rash caused by lapatinib, a dual HER1/2 inhibitor (HER1/2i), and the single HER1 inhibitors (HER1i) cetuximab

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28

Scaife, Wendy A. "Transforming human energy to power for change : development principles for charitable health organisations seeking to optimise community and other support of Australian medical science." Thesis, Queensland University of Technology, 2002. https://eprints.qut.edu.au/36364/1/36364_Digitised%20Thesis.pdf.

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29

Van, der Spuy Gian Dreyer. "Analysis and application of evolutionary markers in the epidemiology of Mycobacterium tuberculosis." Thesis, Stellenbosch : Stellenbosch University, 2008. http://hdl.handle.net/10019.1/1457.

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Thesis (PhD (Biomedical Sciences. Molecular Biology and Human Genetics))--Stellenbosch University, 2008.<br>This series of studies includes both methodological analyses, aimed at furthering our understanding of, and improving the tools used in molecular epidemiology, and investigative projects which have used these tools to add to our knowledge of the M. tuberculosis epidemic. Using serial isolates from tuberculosis patients, we have investigated the evolutionary rate of the IS6110 RFLP pattern. In accordance with other studies, we determined a ½-life for this epidemiological marker of 10.6

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30

Barrie, Elizabeth Stofko. "Genetic Factors Regulating Expression of Dopaminergic Genes." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1406388433.

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31

Bekele, Adane Mihret. "Gene expression and cytokine pattern of pulmonary tuberculosis patients and their contacts in Ethiopia." Thesis, Stellenbosch : Stellenbosch University, 2012. http://hdl.handle.net/10019.1/71942.

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Thesis (PhD)--Stellenbosch University, 2013.<br>ENGLISH ABSTRACT: The immune response against M. tuberculosis is multifactorial, involving a network of innate and adaptive immune responses. Characterization of the immune response, a clear understanding of the dynamics and interplay of different arms of the immune response and the identification of infection-stage specific biomarkers are critical to allow the development of better tools for combating tuberculosis. In an attempt to identify such biomarkers, we studied pulmonary tuberculosis patients and their contacts in Addis Ababa, Ethio

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32

Akinyi, Linnet. "Initial characterization and determination of the molecular mechanism(s) that control transcription of the human PKC epsilon gene in lung cancer cells." [Gainesville, Fla.] : University of Florida, 2004. http://purl.fcla.edu/fcla/etd/UFE0007620.

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Thesis (M.S.)--University of Florida, 2004.<br>Typescript. Title from title page of source document. Document formatted into pages; contains 52 pages. Includes Vita. Includes bibliographical references.

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33

Nelson, David. "Ergonomics interventions as investments in occupational health and safety : A selected series of case studies within the Australian postal corporation." Thesis, University of Ballarat, 2006. http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/33522.

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This thesis examines and reports upon the application of ergonomics interventions to OHS-based industrial problems. The study focuses on the values of these interventions as investment opportunieties for management. A wide review of the scientific and commercial literature, personal information, observation techniques, and a selected series of seven case studies and eleven separate data-sets within the Australian Postal Corporation have been undertaken.<br>Doctor of Philosophy

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34

Loff, Beatrice. "Health and human rights : case studies in the potential contribution of a human rights framework to the analysis of health questions." Monash University, Dept. of Epidemiology and Preventive Medicine, 2004. http://arrow.monash.edu.au/hdl/1959.1/5291.

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35

Stanfield, Zachary. "Comprehensive Characterization of the Transcriptional Signaling of Human Parturition through Integrative Analysis of Myometrial Tissues and Cell Lines." Case Western Reserve University School of Graduate Studies / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=case1562863761406809.

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36

Bilginer, Onur. "Control And Manipulation Of Life: A Critical Assessment Of Genetics Through The Perspectives Of Hans Jonas, Martin Heidegger And Michel Foucault." Master's thesis, METU, 2006. http://etd.lib.metu.edu.tr/upload/12607453/index.pdf.

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This study is on the political and ethical aspects of recent advances in genetics. Its aim is to explicate the scientific and technological premises of genetics along historical, philosophical and political axes by employing the critical perspectives of Jonas, Heidegger and Foucault. Starting the discussion from a brief account of scientific and technological revolutions initiated in the 16th and 17th centuries, I defend the thesis that the idea of control and manipulation of life is not a novelty introduced by genetics, but a historical orientation underlying modern man&rsquo<br>s metaphysica

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37

Ferreira, Mariana Toledo. "A institucionalização da pesquisa em genética no Brasil e seus pesquisadores: um estudo de caso do Centro de Estudos do Genoma Humano da USP." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/8/8132/tde-27012014-110441/.

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Partindo da concepção de que a ciência é, por definição, uma atividade coletiva, organizada localmente e através de instituições, esta dissertação realiza um estudo empírico do Centro de Estudos do Genoma Humano (CEGH), situado na Universidade de São Paulo. A pergunta mais geral do trabalho diz respeito à maneira pela qual se dá a organização social da produção de conhecimento e da produção de produtores de conhecimento em uma área específica de pesquisa a genética em um país periférico. Para isso, parte-se do processo de institucionalização da pesquisa em genética no Brasil, enfatizando os

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38

Bryson, Benjamin Levi. "The Paradoxical Roles of Oncostatin M in Mammary Epithelial Cell Senescence and Transformation." Case Western Reserve University School of Graduate Studies / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=case1510584483133814.

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39

Tabuchi, Tomoko M. "Chromosome-Biased Binding and Function of C. elegans DRM Complex, and Its Role in Germline Sex-Silencing: A Dissertation." eScholarship@UMMS, 2011. https://escholarship.umassmed.edu/gsbs_diss/538.

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DRM is a conserved transcription factor complex that includes E2F/DP and pRB family proteins and plays important roles in the cell cycle and cancer. Recent work has unveiled a new aspect of DRM function in regulating genes involved in development and differentiation. These studies, however, were performed with cultured cells and a genome-wide study involving intact organisms undergoing active proliferation and differentiation was lacking. Our goal was to extend the knowledge of the role of DRM in gene regulation through development and in multiple tissues. To accomplish this, we employed genom

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40

Cortobius, Fredriksson Moa. "ProBenefit : Implementing the Convention on Biological Diversity in the Ecuadorian Amazon." Thesis, Södertörn University College, School of Life Sciences, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:sh:diva-2771.

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<p>Legislation on benefit sharing dates back to 1992 and the commandment of the UNConvention on Biological Diversity, hence implementation still has few cases to fall back on(CBD, 1992). The case study of the project ProBenefit presented by the thesis highlights howlack of deliberation can undermine a democratic process. The objective of the thesis is thatProBenefit’s attempt to implement the standards of the CBD on access and benefit sharingwill highlight not only problems met by this specific project, but difficulties that generallymeet democratic processes in contexts of high inequality. To

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Fok, Ezio Tony. "Modification of the human KRAS gene using CRISPR/Cas9 system." Thesis, 2015. http://hdl.handle.net/10539/17425.

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A dissertation Submitted in fulfilment of the requirements for the degree of Master of Science to the Faculty of Health Sciences at the University of the Witwatersrand, Johannesburg, South Africa. November 2014<br>The genome is comprised of a simple quaternary code that serves as the “software” which governs all the complex processes of life. The successful manipulation of this code holds enormous potential for applications involving genome engineering. However, the tools needed to navigate the complex landscape of the genome and efficiently and precisely introduce engineered modificati

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42

Donaghey, Bronwyn. "Regulating the biological family : policy, genetics, discourse, and diminishing ’other’ bodies." Thesis, 2006. http://hdl.handle.net/2440/57101.

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This thesis identifies and elaborates on the way in which notions of genetic inheritance connect with notions of ’proper’ families and hence shape policies concerning reproduction and family formation. Assumptions about the structure and shape of the ’proper’ or ’traditional’ family - as a heterosexual two-parent unit with biological children - and its claim to naturalness, are embedded in policies related to reproductive technologies and family formation. The thesis explores the discourses surrounding the following specific policies - surrogacy, IVF, adoption, abortion, child support and post

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Donaghey, Bronwyn. "Regulating the biological family : policy, genetics, discourse, and diminishing ’other’ bodies." 2006. http://hdl.handle.net/2440/57101.

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Title page, contents and abstract only. The complete thesis in print form is available from the University of Adelaide Library.<br>This thesis identifies and elaborates on the way in which notions of genetic inheritance connect with notions of ’proper’ families and hence shape policies concerning reproduction and family formation. Assumptions about the structure and shape of the ’proper’ or ’traditional’ family - as a heterosexual two-parent unit with biological children - and its claim to naturalness, are embedded in policies related to reproductive technologies and family formation. The thes

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44

Hogbin, Patricia May. "Conservation outcomes arising from research into the population genetics, taxonomy and reproductive ecology of the endangered plant Zieria prostrata." Phd thesis, 2001. http://hdl.handle.net/1885/146021.

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Allan, Sonia Marie. "The regulation of research involving human embryos and cloning in the United Kingdom and Australia." 2009. http://repository.unimelb.edu.au/10187/5753.

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This thesis analyses the nature, rationale, and implementation of United Kingdom and Australian regulation of research involving human embryos and cloning using legal materials, other documents and qualitative interviews with researchers, practitioners and regulators. It considers how law-makers have decided upon what to regulate and where to draw the line between permissible and prohibited activities, and the type of regulatory design strategies and enforcement approaches adopted in each jurisdiction (the ‘how to regulate’ question). It is argued that both jurisdictions have effectively dec

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46

McAra, Sally 1967. "A "stupendous attraction" : materialising a Tibetan Buddhist contact zone in rural Australia." 2009. http://hdl.handle.net/2292/5234.

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When people, ideas or things migrate across cultural milieux, many opportunities for cultural transformation arise. The focal point of this thesis is a large stupa/temple (Great Stupa) being built at Atisha Centre, a Buddhist retreat near Bendigo in Australia, by members of an international organisation called the Foundation for the Preservation of the Mahayana Tradition (FPMT). I approach the planning, promotion and construction of the stupa as an instance of the transplantation of religious material culture, arguing that Atisha Centre and particularly the stupa play a constitutive role by ac

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47

Foong, CK. "A comparative analysis of the medico-legal and ethical issues associated with embryonic stem cell research in Australia and Malaysia." Thesis, 2012. https://eprints.utas.edu.au/14752/1/front-foong-thesis.pdf.

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This thesis critically evaluates the regulatory framework governing the contentious area of human embryonic stem cell (HESC) research in Australia which has a long record of regulating in vitro fertilisation (IVF) and embryo research.It proposes an effective model, based on regulatory theories and is similar to the Australian regulatory framework, for the Malaysian government to adopt to regulate the research.

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48

Hill, Jane Adair. "Phenotypic and genetic parameters for the S.A. Strongwool merino strain with an emphasis on skin characters as early indicators of wool productivity." 2001. http://web4.library.adelaide.edu.au/theses/09PH/09phh6463.pdf.

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Bibliography: leaves 325-341. Skin and fleece measurements were recorded at different ages for both male and female sheep from the Turretfield Merino Resource Flock and used to estimate the heritability of each trait and the phenotypic and genetic correlations among and between the skin and fleece traits. Generally, the heritability of each trait was high, which indicates that both the fleece and skin traits should respond well to selection.

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Whitau, Rose Hannah. "Late Quaternary human-environment interaction in Bunuba and Gooniyandi country, Western Australia." Phd thesis, 2018. http://hdl.handle.net/1885/147693.

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In north Western Australia, records of palaeoenvironmental change are scarce or under explored, particularly terrestrial archives that allow for comparison with the archaeological record and examination of human-environment interaction in the past. The extent to which these records reflect localised vegetation responses to climate fluctuations, and the manner in which people adapted to these changes in climate and vegetation, has yet to be investigated within the context of stratified archaeological inquiry. Analysis of archaeobotanical proxies excavated in association with other cultur

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Chen, Bo-Juen. "Personalized Medicine: Studies of Pharmacogenomics in Yeast and Cancer." Thesis, 2013. https://doi.org/10.7916/D8J109C0.

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Advances in microarray and sequencing technology enable the era of personalized medicine. With increasing availability of genomic assays, clinicians have started to utilize genetics and gene expression of patients to guide clinical care. Signatures of gene expression and genetic variation in genes have been associated with disease risks and response to clinical treatment. It is therefore not difficult to envision a future where each patient will have clinical care that is optimized based on his or her genetic background and genomic profiles. However, many challenges exist towards the full real

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