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Dissertations / Theses on the topic 'Human papillomavirus'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Kan, Chin-Yi. "Human Papillomavirus in human breast cancer and cellular immortalisation." Sydney : University of New South Wales. Biotechnology and Biomolecular Sciences, 2007. http://www.library.unsw.edu.au/~thesis/adt-NUN/public/adt-NUN20071004.080541/.

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2

Brestovac, Brian. "Human papillomavirus and cervical cancer in Western Australia." University of Western Australia. School of Biomedical and Chemical Sciences, 2005. http://theses.library.uwa.edu.au/adt-WU2006.0037.

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3

Aaltonen, Leena-Maija. "Laryngeal human Papillomavirus infection." Helsinki : University of Helsinki, 1999. http://ethesis.helsinki.fi/julkaisut/laa/haart/vk/aaltonen/.

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4

Dareng, Eileen Onyeche. "Human papillomavirus infections and human papillomavirus associated diseases in Nigeria : distribution, determinants and control." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/284551.

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Background: Persistent infection with high risk HPV is a necessary but insufficient cause of cervical cancer. Behavioural, viral and host factors modulate the risk of HPV persistence. In this thesis, I explore the role of the vaginal microbiota, a host factor and the presence of multiple HPV infections, a viral factor in HPV persistence. Considering the limited data on the epidemiology of HPV related diseases in low and middle-countries (LMIC), and the limited success of cervical cancer screening strategies in many LMIC, I provide data on the distribution of HPV related diseases in Nigeria and

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5

Mellin, Hanna. "Human papillomavirus in tonsillar cancer /." Stockholm : Karolinska Univ. Press, 2002. http://diss.kib.ki.se/2002/91-7349-366-X/.

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6

Cooper, Kumarasen. "Human papillomavirus and cervical carcinogenesis." Thesis, University of Oxford, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.306091.

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7

Dowen, Sally Elizabeth. "Human papillomavirus / host genetic interactions." Thesis, University of Cambridge, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.620590.

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8

Dao, Luan D. "Human papillomavirus segregation and replication /." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2008. https://www.mhsl.uab.edu/dt/2008p/dao.pdf.

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9

Cubie, Heather A. "Human papillomavirus : pathogenesis and immunity." Thesis, University of Edinburgh, 1989. http://hdl.handle.net/1842/27846.

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The involvement of human papilloma virus (HPV) in the aetiology and progression of cervical intraepithelial neoplasia (CIN) is still unresolved. This study was designed to assess the immunological responses to HPV types in patients presenting with varying degrees of CIN and in control groups, using in vitro measures of cellular and humoral responses. Lymphocyte proliferation assays (LPA) were performed using peripheral blood mononuclear cells (PBM) and various papillomavirus (PV) antigens. Twenty -five per cent (23/92) of patients with CIN responded to antigens derived from purified BPV, HPV -

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10

Raleigh, Sarah Elizabeth. "Hispanic Parents' Knowledge, Attitudes and Beliefs Toward Human Papillomavirus and Human Papillomavirus Vaccination in Arizona." Diss., The University of Arizona, 2016. http://hdl.handle.net/10150/612848.

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Human papillomavirus (HPV) is a sexually transmitted infection that represents a serious health issue that can lead to significant morbidity and mortality. Although FDA-approved vaccines for the prevention against the majority of strains responsible for cervical cancer and genital warts have been available for many years, immunization rates remain low. This study will consider cervical cancer as the main consequence of HPV and thus will investigate parents of daughters. This is of particular relevance to Arizona, given the large Hispanic population and the racial and ethnic disparities that

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11

Moberg, Martin. "Human Papillomavirus Load and Cervical Carcinoma." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4256.

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12

Geijersstam, Veronika af. "Dynamics of oncogenic human papillomavirus infection /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4459-8/.

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13

Browne, Helena Margaret. "Studies on human papillomavirus type 16." Thesis, University of Cambridge, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.238642.

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14

Varsani, Arvind. "Development of candidate Human papillomavirus vaccines." Doctoral thesis, University of Cape Town, 2003. http://hdl.handle.net/11427/5970.

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Bibliography: leaves 180-218.<br>The objective of this thesis was to investigate novel and plant-based vaccines against the Human papillomavirus type 16 (HPV-16), which is primarily responsible for cervical cancer. As a first study, the L1 gene of a South Africna variant of HPV-16 (L1 504) and a mutant (504[ΔA266T]), where the alanine at 266 was mutated to a threonine, were expressed in insect cells by recombinant baculovirus, and the resulting virus-like particles (VLPs) were tested with a panel of well-characterised monoclonal antibodies (Mabs).

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15

Nielson, Carrie. "Human Papillomavirus Prevalence in Asymptomatic Men." Diss., The University of Arizona, 2006. http://hdl.handle.net/10150/194193.

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Introduction: Human papillomavirus (HPV) is the sexually transmitted etiologic agent of cervical cancer. While HPV infects both men and women, little is known about HPV infection in men. Specifically, knowledge of the prevalence of type-specific HPV infection and the distribution of these infections by anogenital anatomic site in men is incomplete. Evaluation of factors associated with HPV infection based on complete anogenital sampling and with HPV-16 antibody detection may lead to a better understanding of HPV transmission and prevention.Methods: A total of 493 asymptomatic men ages 18 to 40

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16

Cranston, Ross Douglas. "Clinical and molecular aspects of anal human papillomavirus, human papillomavirus associated anal squamous intraepithelial lesions, and anal cancer." Thesis, University of Edinburgh, 2008. http://hdl.handle.net/1842/29078.

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In a population of men who have sex with men (MSM), anal HPV is common with 61% of HIV-negative and 93% of HIV-positive men testing positive for the virus using the polymerase chain reaction (PCR) technique. MSM also have high rates of anal dysplasia, the putative precursor of anal cancer. The goal of this thesis is to describe clinical and molecular aspects of anal human papillomavirus, and its associated anal lesions, and has four main aims. Identification of risk factors for the development of anal cancer: high-grade anal dysplasia may be a risk factor or marker for the subsequent developme

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17

Richardson, Lyndsay. "Human Papillomavirus DNA testing with cytology triage in cervical screening: Influence of revealed versus concealed Human Papillomavirus Status." Thesis, McGill University, 2011. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=104865.

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Introduction: The causal association between Human Papillomavirus (HPV) and cervical cancer has enabled developments in modern cervical screening technologies. In place of traditional Papanicolaou (Pap) testing as the sole screening modality, support is mounting for primary screening via tests for HPV DNA detection, reserving Pap cytology for triage of HPV-positive women. Since interpretation of Pap smears is a subjective procedure, revealing HPV-positivity may influence cytotechnician assessments of cellular abnormalities. Objectives: We simulated the HPV/Pap triage algorithm within three dif

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18

Weyn, Christine. "Human papillomavirus prevalence and expression in trophoblastic and cervical cells." Doctoral thesis, Universite Libre de Bruxelles, 2010. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210012.

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Human papillomavirus (HPV) is a double-stranded DNA virus, typically infecting mucosal or cutaneous epithelial keratinocytes. Today, more than 118 different HPV types have been formally described. Sexual transmission of mucosal HPVs is very common and generally asymptomatic, but HPV infection can be associated with benign lesions such as condylomata acuminata or, in rare cases, with malignant lesions such as cervical cancer. Two prophylactic vaccines are currently available in Europe, protecting against HPV-16 and HPV-18 (Cervarix&63720;) or against HPV-6, HPV-11, HPV-16 and HPV-18 (Gardasil&6

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19

Higgins, Geoffrey David. "Human papillomavirus RNA transcripts in anogenital neoplasia /." Title page, contents and outline only, 1991. http://web4.library.adelaide.edu.au/theses/09PH/09phh6358.pdf.

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20

Hirsch, Brooke Bishop. "Structural studies of human papillomavirus capsid proteins /." Connect to full text via ProQuest. Limited to UCD Anschutz Medical Campus, 2007.

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Thesis (Ph.D. in Molecular Biology) -- University of Colorado Denver, 2007.<br>Typescript. Includes bibliographical references (leaves 96-117). Free to UCD affiliates. Online version available via ProQuest Digital Dissertations;

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21

Jarrell, Jennifer C. "Human Papillomavirus Vaccine Policy in the U.S." Digital Archive @ GSU, 2007. http://digitalarchive.gsu.edu/iph_theses/30.

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HPV vaccine school entry mandates and vaccine funding by state was examined using the Diffusion of Innovations (DOI) theory. The DOI was applied to HPV immunization policy to evaluate the rate of vaccine adoption and to determine whether associations existed between an empirical need for vaccine adoption and action by the states. State-level data on political characteristics, health and policy were collected from several secondary sources. Data analyses were performed utilizing SPSS logistic regression models. Odds rations were used to evaluate the associations between the independent and dep

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22

Woodrow, Sarah Louise. "Mechanisms of human papillomavirus-induced benign proliferation." Thesis, University of London, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.405572.

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23

Marongiu, L. "Human papillomavirus genome status in cervical samples." Thesis, University College London (University of London), 2014. http://discovery.ucl.ac.uk/1427690/.

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Infection with oncogenic Papillomavirus genotypes is considered a major risk factor for the development of cervical cancer; nonetheless only a small proportion of the infected patients actually develop malignancies. The specific identification of high grade lesions is pivotal to increase the effectiveness of the cervical cancer screening. In the present study promising candidate molecular biomarkers based on the Human Papillomavirus (HPV) genomes were assessed in a cross-sectional cohort formed by samples singly infected with the most prevalent oncogenic genotypes 16, 18, 31 and 45. The candid

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24

Hillman, R. J. "Aspects of the epidemiology of human papillomavirus." Thesis, University of Edinburgh, 1994. http://hdl.handle.net/1842/21303.

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The objective of this thesis was to investigate various aspects of the epidemiology of human papillomavirus (HPV). Prospective studies were performed on a total of 334 patients attending to genitourinary medicine departments in London. The patients had either clinical indications for genital biopsy, urethral gonorrhoea, anogenital warts or a current partner with anogenital warts. Biopsy, scrape, swab and blood samples were taken. In addition, a new method, the "Superglue (SG) technique" was devised. HPV types 6, 11, 16, 18, 31 and 33 were identified in the specimens by DNA extraction followed

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25

Nash, Ashley. "Predictors of Human Papillomavirus Vaccination in Georgia." ScholarWorks, 2017. https://scholarworks.waldenu.edu/dissertations/4084.

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Although the human papillomavirus (HPV) vaccine has been approved by the Federal Drug Administration (FDA) and is available for males and females, completion of the 3-shot series in Georgia remains relatively low. The purpose of this study was to examine the predictors of HPV vaccination initiation and completion for male and female adolescents, ages 13 to 17 years old, in Georgia between 2013 and 2015. The theoretical foundation of the study was the structural model of health behavior which is an ecological model. Logistic regression was performed to determine if there was any relationship be

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26

Gaspar, Joice. "Perfil sociodemográfico e clínico de mulheres com infecção genital pelo Papilomavirus humano atendidas em um hospital de referência do interior paulista." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/22/22132/tde-26092013-151558/.

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Introdução: A infecção pelo Papilomavirus humano (HPV) enquadra-se como um problema de saúde pública, sendo considerada a infecção sexualmente transmissível (IST) mais comum. Estima-se, mundialmente, que aproximadamente 600 milhões de pessoas possuam o vírus do HPV e que em torno de 75 a 80% das pessoas adquiram- no em algum momento da vida. Objetivo: Analisar os aspectos sociodemográficos e clínicos em mulheres com infecção genital pelo HPV associando-os com o tipo de lesão genital e a sorologia reagente ou não reagente para o HIV e avaliar o seguimento clínico de mulheres com lesão int

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27

Cheung, Ying Kit. "Study of the immunity of a human papillomavirus vaccine candidate /." View Abstract or Full-Text, 2003. http://library.ust.hk/cgi/db/thesis.pl?BIOL%202003%20CHEUNG.

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Thesis (M. Phil.)--Hong Kong University of Science and Technology, 2003.<br>Includes bibliographical references (leaves 112-129). Also available in electronic version. Access restricted to campus users.

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28

Bryan, Donna Sarah. "Regulation of interleukin-6 activity in human keratinocytes by human papillomavirus." Thesis, Queen Mary, University of London, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286270.

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29

Seagar, Amie-Louise. "The role of human papillomavirus in cervical disease." Thesis, University of Edinburgh, 2002. http://hdl.handle.net/1842/25171.

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The work presented in this thesis was performed to investigate the role of human papillomavirus (HPV) testing for improved detection of cervical neoplasia in the Scottish Screening Programme (CSP). A longitudinal study of 975 archived cervical smears from women who had histologically-confirmed cervical intraepithelial neoplasia (CIN) showed that HPV positivity using Hybrid Capture Assay II (HCAII) was found to increase with increased cytological abnormality and 18% overall contained high-risk HPV (HR-HPV) DNA. Retrospective analysis of cytology data showed that the positive predictive value (P

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30

Healey, Sylvia M. "Human papillomavirus infection and cervical dysplasia in Nunavut." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0011/MQ52906.pdf.

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31

Mistry, Nitesh. "Human papillomavirus tropism : determinants of viral tissue specificity." Doctoral thesis, Umeå : Univ, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1149.

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32

Siliņš, Ilvars. "Molecular epidemiology of human papillomavirus and cervical cancer /." Stockholm : [Karolinska institutets bibl.], 2001. http://diss.kib.ki.se/2001/91-7349-091-1/.

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33

Jarrell, Jennifer C. "Human papillomavirus vaccine policy in the United States." unrestricted, 2007. http://etd.gsu.edu/theses/available/etd-12052007-202826/.

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Thesis (M.P.H.)--Georgia State University, 2007.<br>Title from file title page. Russ Toal, committee chair; Michael Eriksen, Cristen J. Suhr, committee members. Electronic text (76 p. : ill., col. map) : digital, PDF file. Description based on contents viewed Feb. 25, 2008. Includes bibliographical references (p. 66-72).

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34

Šepetienė, Agnė. "Cervical intraepithelial lesions and integration of human papillomavirus." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2011. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2011~D_20110307_144558-96943.

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This dissertation observes the association between human papillomavirus (HPV) integration into the host cell genome and cervical intraepithelial lesions. The aim of this study is to determine how the grade of HPV16 DNA integration into the host cell genome (HPV E2 gene deletion) is related to cervical intraepithelial lesions. 253 women were screened for HPV infection and the majority was diagnosed with HPV type 16. The most frequently determined was HPV grade II integration. No statistically significant difference was defined while analyzing the relations between the status of HPV E2 gene inte

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35

Massimi, Paola. "Functional studies of the human papillomavirus E7 protein." Thesis, Open University, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300324.

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36

Carlotti, Franco Paul. "The E7 protein of Human Papillomavirus Type 16." Thesis, University of Cambridge, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.308419.

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37

Yeudall, W. Andrew. "Human papillomavirus types in oral squamous cell carcinogenesis." Thesis, University of Glasgow, 1991. http://theses.gla.ac.uk/40921/.

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The DNAs of human papillomavirus (HPV) types 4, 16 and 18 have been detected in biopsies of normal and malignant human oral mucosa by Southern blot hybridisation and polymerase chain reaction (PCR). By the former technique HPV-4, HPV-16 and HPV-18 DNAs were detected in three separate carcinomas, but only found in adjacent dysplastic and normal tissue by PCR. The PCR technique also allowed detection of HPV-16 and HPV-18 DNA in additional carcinomas and normal samples. The oral HPV-4 DNA has been molecularly cloned and extensive restriction analysis and nucleotide sequencing showed identity with

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38

Altaparmakova, Mary Collette. "Human papillomavirus early proteins and cellular DNA replication." Thesis, University of Cambridge, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.615159.

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39

Forster, A. S. "The human papillomavirus immunisation programme and sexual behaviour." Thesis, University College London (University of London), 2011. http://discovery.ucl.ac.uk/1301995/.

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The introduction of human papillomavirus (HPV) vaccination has caused some parents to report concern that their daughters may change their sexual behaviour following vaccination. This concern consistently relates to vaccination acceptance, but had not been investigated in detail. Accordingly, five studies addressed the thesis objective: to explore parents’ concern about adolescent sexual behaviour following HPV vaccination in the context of the UK immunisation programme and to examine whether such concerns were justifiable. The first study examined discussions of risky sexual behaviour and HPV

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40

Wall, Sion Richard. "Host-virus interactions in human papillomavirus mediated disease." Thesis, Cardiff University, 2004. http://orca.cf.ac.uk/55555/.

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Human Papillomavirus (HPV) is the cause of a wide spectrum of disease ranging from benign cutaneous warts to malignant anogenital tumours. Two notable features of HPV diseases are that the viruses are highly tissue specific of individual HPV types and the fact that while HPV infections are common only a minority of infected individuals manifest clinical disease, indicating the importance of host virus interactions. In this thesis two HPV mediated diseases have been examined in detail, cervical cancer and Recurrent Respiratory Papillomatosis. Cervical cancer is a major cause of mortality in wom

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41

Flynn, Áine Sinéad. "Nucleoside analogue drugs and human papillomavirus associated neoplasia." Thesis, Cardiff University, 2013. http://orca.cf.ac.uk/58775/.

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The anti-viral acyclic nucleoside monophosphate compound Cidofovir has shown efficacy in treatment of Human Papillomavirus (HPV) associated genital intraepithelial neoplasia; however, the mechanism of action of Cidofovir in this setting has not been determined. This investigation focused on modifying nucleoside analogue compounds to increase their efficacy in HPV positive cell models of disease, in addition to determining the molecular mechanism of action of Cidofovir in premalignant HPV associated intraepithelial neoplasia. ProTide modification increases the efficacy of nucleoside analogue co

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42

Subramaniam, Natasha Marie. "Addressing Human Papillomavirus Vaccination in Primary Care Pediatrics." ScholarWorks, 2019. https://scholarworks.waldenu.edu/dissertations/7434.

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Human papillomavirus (HPV) is the most common sexually transmitted disease in the United States. Despite most common transmission, HPV immunization in adolescents remains below target rates of 80% as outlined by Healthy People 2020 Objectives. Nearly all individuals will contract HPV during their lifetime. The purpose of this project was to educate providers on successfully promoting HPV immunization in adolescents utilizing evidence-based methods. The health belief model (HBM) was the theoretical underpinning utilized to teach providers on discussions about 9vHPV immunization with parents of

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43

Drobni, Peter. "Papillomavirus binding and entry : The heparan sulfate receptor and inhibition by lactoferrin." Doctoral thesis, Umeå : Department of Clinical Microbiology, Virology, Umeå universitet, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-550.

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44

Zheng, Biying. "Improved human papillomavirus DNA typing methods and biology of cervical cancer /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-795-2/.

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45

Andersson, Sonia. "The role of human papillomavirus in adenocarcinoma of the uterine cervix /." Stockholm, 2002. http://diss.kib.ki.se/2002/91-7349-209-4.

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46

Öberg, Daniel. "The role of polyadenylation in human papillomavirus type 16 late gene expression /." Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl.[distributör], 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4774.

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47

Meys, Rhonda. "Aspects of human papillomavirus (HPV) disease in human immunodeficiency virus (HIV) infection." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/10730.

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Cutaneous and genital human papillomavirus (HPV) infection in HIV patients, on suppressive anti-retroviral therapy (ART), poses under-investigated clinical challenges. HPV in HIV may represent a form of immune reconstitution associated disease (IRAD). HPV disease and IRADs have been separately correlated with human leucocyte antigen (HLA) genotype. HLA might also influence HPV in HIV. Comprehensive HPV typing of persistent warts obtained from HIV infected and healthy subjects was performed. Cutaneous HPV types were detected using nested PCR/sequencing and newly developed (Luminex based) HSLPCR

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48

Gu, Zhengming. "Studies on molecular mechanisms of transformation by human papillomavirus : the role of E6 and E5 oncogenes." Thesis, McGill University, 1996. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=40133.

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The ability of the HPV-18 E6 gene to impair p53-mediated transcriptional activity induced by DNA damaging agents was investigated. It is demonstrated that E6 can abolish DNA damage induced p53-mediated transcription and that a region from amino acid residue 113 to 117 of HPV-18 E6 protein was necessary for E6 to direct the degradation of p53. The biological importance of the E6/p53 interaction was then directly examined in HPV-16 containing cervical carcinoma derived cells by introducing the monomeric p53 mutant which is resistant to E6 mediated degradation. The two major observations made fro

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49

Zhao, Xiaomin. "Regulation of Human Papillomavirus Type 16 mRNA Splicing and Polyadenylation." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5919.

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50

Holguin, Ashlee Cooper. "Determining the Knowledge & Attitudes of 18-to 26- Year Old Women Regarding Cervical Cancer, Human Papillomavirus, and The Human Papillomavirus Vaccine." DigitalCommons@USU, 2009. https://digitalcommons.usu.edu/etd/464.

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This study applied the constructs of the health belief model (HBM) to assess women's knowledge and attitudes (i.e., perceived susceptibility, perceived severity, perceived benefits and perceived barriers) regarding cervical cancer, HPV, and the HPV vaccine and determine whether they predict women's intentions to receive the HPV vaccine. Women aged 18 to 26 years were surveyed from a convenience sample, and were primarily well-educated White women. Using Polytomous Universal Model (PLUM) ordinal regression, it was determined that the constructs of this model could not predict women's intentions

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