Relevant bibliographies by topics / Human Umbilical Cord Matrix-Derived Mesenchymal Cells

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Human Umbilical Cord Matrix-Derived Mesenchymal Cells'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Human Umbilical Cord Matrix-Derived Mesenchymal Cells"

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Dhitiseith, D., and S. Honsawek. "Differential Expression of Osteogenic Differentiation in Human Umbilical Cord Wharton’s Jelly-Derived Mesenchymal Stem Cells Treated with Demineralized Bone." Advanced Materials Research 55-57 (August 2008): 697–700. http://dx.doi.org/10.4028/www.scientific.net/amr.55-57.697.

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Mesenchymal stem cells are multipotential cells capable of differentiating into osteoblasts, chondrocytes, adipocytes, tenocytes, and myoblasts. Wharton’s jelly consists of stem cells that are a rich source of primitive multipotent mesenchymal cells. Demineralized bone matrix (DBM) has been widely utilized as a biomaterial to promote new bone formation. We isolate and characterize umbilical cord Wharton’s Jelly-derived mesenchymal stem (UCMS) cells derived from Wharton’s jelly and examine the biological activity of DBM in this cell line. Osteoblast differentiation of the UCMS cells was determi
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Kacham, Santhosh, Tejal Sunil Bhure, Sindhuja D. Eswaramoorthy, et al. "Human Umbilical Cord-Derived Mesenchymal Stem Cells Promote Corneal Epithelial Repair In Vitro." Cells 10, no. 5 (2021): 1254. http://dx.doi.org/10.3390/cells10051254.

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Corneal injuries are among the leading causes of blindness and vision impairment. Trauma, infectious keratitis, thermal and chemical (acids and alkali burn) injuries may lead to irreversible corneal scarring, neovascularization, conjunctivalization, and limbal stem cell deficiency. Bilateral blindness constitutes 12% of total global blindness and corneal transplantation remains a stand-alone treatment modality for the majority of end-stage corneal diseases. However, global shortage of donor corneas, the potential risk of graft rejection, and severe side effects arising from long-term use of im
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Lv, Hong Wei, Yin Zhang, Mei Yu Sun, et al. "Matrix Elasticity Affects Integrin Expression in Human Umbilical Cord-Derived Mesenchymal Stem Cells." Materials Science Forum 815 (March 2015): 412–23. http://dx.doi.org/10.4028/www.scientific.net/msf.815.412.

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Mesenchymal stem cells (MSCs) are a powerful cellular alternative for regenerative medicine and tissue engineering applications due to their multipotency. It is becoming increasingly clear that elasticity of extracellular matrix (ECM) has a profound effect on cell phenotype including adhesion, proliferation and differentiation. Integrins are considered to be important mechanoreceptors in mechanotransduction. While numerous studies have focused on α2, β1 and β3 integrin involvement in substrate stiffness-driven commitment of bone marrow MSCs, comparatively little is known about the change of α5
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Lombardo, Marta Tiffany, Martina Gabrielli, Florence Julien-Marsollier, et al. "Human Umbilical Cord-Mesenchymal Stem Cells Promote Extracellular Matrix Remodeling in Microglia." Cells 13, no. 19 (2024): 1665. http://dx.doi.org/10.3390/cells13191665.

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Human mesenchymal stem cells modulate the immune response and are good candidates for cell therapy in neuroinflammatory brain disorders affecting both adult and premature infants. Recent evidence indicates that through their secretome, mesenchymal stem cells direct microglia, brain-resident immune cells, toward pro-regenerative functions, but the mechanisms underlying microglial phenotypic transition are still under investigation. Using an in vitro coculture approach combined with transcriptomic analysis, we identified the extracellular matrix as the most relevant pathway altered by the human
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Harahap, Dianita Halimah, and Gampo Alam Irdam. "Human umbilical cords mesenchymal stem cells for kidney diseases." Bali Medical Journal 11, no. 1 (2022): 155–59. http://dx.doi.org/10.15562/bmj.v11i1.3085.

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Stem cell therapy is an emerging therapy in the medical field. Recent studies show that stem cell therapy gives promising results. One of the stem cell sources is the human umbilical cord that has many potential, not only for therapy alone but also for banking. Human umbilical cord mesenchymal stem cells (HUCMSCs) have greater advantages than bone marrow and adipose tissue-derived stem cells in isolating the cells and the shortest culture period. Studies on animal models showed improvement of kidney disease in the various mechanism. Human studies regarding human umbilical cord mesenchymal stem
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Pham, Liem Hieu, Ngoc Bich Vu, and Phuc Van Pham. "The subpopulation of CD105 negative mesenchymal stem cells show strong immunomodulation capacity compared to CD105 positive mesenchymal stem cells." Biomedical Research and Therapy 6, no. 4 (2019): 3131–40. http://dx.doi.org/10.15419/bmrat.v6i4.538.

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Introduction: Human mesenchymal stem cells (MSCs) are the most popular stem cells applied in disease treatment. MSCs can be isolated and in vitro expanded from various sources such as bone marrow, peripheral blood, umbilical cord blood, umbilical cord tissue, and adipose tissue. According to Dominici et al. (2006), MSCs should express CD105, an essential marker used to confirm MSCs. However, some recent studies have show that MSCs contained a subpopulation that is negative for CD105. This study aimed to compare the immune modulation capacity of 2 populations of CD105 positive (CD105+) and nega
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Varkouhi, Amir K., Mirjana Jerkic, Lindsay Ormesher та ін. "Extracellular Vesicles from Interferon-γ–primed Human Umbilical Cord Mesenchymal Stromal Cells Reduce Escherichia coli–induced Acute Lung Injury in Rats". Anesthesiology 130, № 5 (2019): 778–90. http://dx.doi.org/10.1097/aln.0000000000002655.

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Abstract Editor’s Perspective What We Already Know about This Topic What This Article Tells Us That Is New Background Human umbilical cord mesenchymal stromal cells possess considerable therapeutic promise for acute respiratory distress syndrome. Umbilical cord mesenchymal stromal cells may exert therapeutic effects via extracellular vesicles, while priming umbilical cord mesenchymal stromal cells may further enhance their effect. The authors investigated whether interferon-γ–primed umbilical cord mesenchymal stromal cells would generate mesenchymal stromal cell–derived extracellular vesicles
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Salehinejad, Parvin, Noorjahan Banu Alitheen, Abdul Manaf Ali, et al. "Neural differentiation of human umbilical cord matrix-derived mesenchymal cells under special culture conditions." Cytotechnology 67, no. 3 (2014): 449–60. http://dx.doi.org/10.1007/s10616-014-9703-6.

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Latifpour, Mostafa, Seyed Noureddin Nematollahi-Mahani, Massoud Deilamy, et al. "Improvement in Cardiac Function following Transplantation of Human Umbilical Cord Matrix-Derived Mesenchymal Cells." Cardiology 120, no. 1 (2011): 9–18. http://dx.doi.org/10.1159/000332581.

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Arutyunyan, Irina, Andrey Elchaninov, Andrey Makarov, and Timur Fatkhudinov. "Umbilical Cord as Prospective Source for Mesenchymal Stem Cell-Based Therapy." Stem Cells International 2016 (2016): 1–17. http://dx.doi.org/10.1155/2016/6901286.

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The paper presents current evidence on the properties of human umbilical cord-derived mesenchymal stem cells, including origin, proliferative potential, plasticity, stability of karyotype and phenotype, transcriptome, secretome, and immunomodulatory activity. A review of preclinical studies and clinical trials using this cell type is performed. Prospects for the use of mesenchymal stem cells, derived from the umbilical cord, in cell transplantation are associated with the need for specialized biobanking and transplant standardization criteria.
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Dissertations / Theses on the topic "Human Umbilical Cord Matrix-Derived Mesenchymal Cells"

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Ohta, Naomi. "Human umbilical cord matrix mesenchymal stem cells suppress the growth of breast cancer by expression of tumor suppressor genes." Thesis, Kansas State University, 2013. http://hdl.handle.net/2097/16730.

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Master of Science<br>Department of Anatomy and Physiology<br>Masaaki Tamura<br>Previous studies have shown that both human and rat umbilical cord matrix mesenchymal stem cells (UCMSC) possess the ability to control the growth of breast carcinoma cells. Comparative analysis of two types of UCMSC suggest that rat UCMSC-dependent growth regulation is significantly stronger than that of human UCMSC. Accordingly, the present study was designed to clarify their different tumoricidal abilities by analyzing gene expression profiles in two types of UCMSC. Gene expression profiles were studied by microa
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Gu, Wenduo. "Smooth muscle differentiation from human umbilical cord derived mesenchymal stem cells : miRNA-involved mechanism and potential application for vascular tissue engineering." Thesis, King's College London (University of London), 2017. https://kclpure.kcl.ac.uk/portal/en/theses/smooth-muscle-differentiation-from-human-umbilical-cord-derived-mesenchymal-stem-cells(a4f2009e-1f83-484b-b1d9-18a2babf71af).html.

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Tissue engineered vascular grafts with long term patency are in great need in the clinics. An accessible source of human smooth muscle cell (SMC) is important for constructing functional vascular grafts. Human mesenchymal stem cells from the umbilical cord (UCMSCs) exhibit multi-lineage differentiation abilities, including the potential to differentiate towards vascular lineages such as SMCs. MicroRNAs (miRNAs) are short non-coding regulatory RNAs. They widely participate in regulation of stem cell differentiation and may play an important role in SMC differentiation. Understanding how to gene
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Seshareddy, Kiran Babu. "Human Wharton’s jelly cells-isolation and characterization in different growth conditions." Thesis, Kansas State University, 2008. http://hdl.handle.net/2097/1054.

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Master of Science<br>Department of Anatomy and Physiology<br>Mark L. Weiss<br>Wharton's jelly is a non-controversial source of mesenchymal stromal cells. Isolation of the cells is non-invasive and painless. The cells have been shown to have a wide array of therapeutic applications. They have improved symptoms when transplanted in a variety of animal disease models, can be used in tissue engineering applications to grow living tissue ex vivo for transplantation, and can be used as drug delivery vehicles in cancer therapy. The cells have also been shown to be non-immunogenic and immune supp
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Selich, Anton [Verfasser], Axel [Akademischer Betreuer] Schambach, and Andrea [Akademischer Betreuer] Hoffmann. "Lentiviral genetic barcoding for functional characterization of human umbilical cord derived mesenchymal stromal cells / Anton Selich ; Akademische Betreuer: Axel Schambach, Andrea Hoffmann ; Institut Experimentelle Hämatologie." Hannover : Bibliothek der Medizinischen Hochschule Hannover, 2020. http://d-nb.info/1212864921/34.

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Helwig, Bryan Glen. "Neuronal differentiation of stem cells derived from human umbilical cord matrix /." Search for this dissertation online, 2003. http://wwwlib.umi.com/cr/ksu/main.

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Lovati, A. B. "COMPARISON OF EQUINE BONE MARROW-, UMBILICAL CORD MATRIX-, AMNIOTIC FLUID- AND TENDON-DERIVED PROGENITOR CELLS." Doctoral thesis, Università degli Studi di Milano, 2010. http://hdl.handle.net/2434/150197.

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Mesenchymal stem cells have been recently investigated for their potential use in regenerative medicine. It has been suggested that there may be a stem cell population within both umbilical cord matrix and amniotic fluid. However, little knowledge exists about the characteristics of these progenitor cells within these sources in the equine species. This study wanted to investigate an alternative and non-invasive stem cell source for the equine tissue engineering and to learn more about the properties of these cells for future cell banking. Moreover, population of adult stem cells were recently
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滝川, 幸子, and Sachiko Takikawa. "Human umbilical cord-derived mesenchymal stromal cells promote sensory recovery in a spinal cord injury rat model." Thesis, 2013. http://hdl.handle.net/2237/18963.

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TIEN, CHIA-YI, and 田家怡. "Investigating therapeutic effect of sequential transplantation of human umbilical cord derived mesenchymal stem cells after experimental spinal cord injury." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/19371095013351133102.

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碩士<br>南臺科技大學<br>生物科技系<br>104<br>Spinal cord injury (SCI) is spinal cord and nerves damage by trauma, resulting in motor, sensory and excretory dysfunctions. There are more than 65,000 patients with spinal cord injury in Taiwan nowadays. SCI not only seriously affect victims' personal and family lives, but also cost a lot of resources from community. Current treatments for SCI include medications, medical procedures, functional rehabilitation, gene therapy and other modalities. Unfortunately, those treatments have their limits and there is no real functional recovery experience. Therefore, to f
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Pereira, Plácido Júnio da Paixão. "Characterization of human umbilical cord matrix mesenchymal stem cells isolated and cultured on tunable hydrogel-based platforms." Master's thesis, 2013. http://hdl.handle.net/10316/24709.

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Dissertação de mestrado Biologia Celular e Molecular, apresentada ao Departamento de Ciências da Vida da Faculdade de Ciências e Tecnologia da Universidade de Coimbra.<br>Está descrito que as células mesenquimais estaminais (MSCs) são extremamente reactivas à modulação por mecanotransdução (Chen, 2008; Eyckmans et al., 2011; Moore et al., 2010), nomeadamente através da expressão tipica de genes especificos da linhagem de certos tecidos quando cultivados in vitro em substratos com propriedades mecanicas similares ás dos mesmos. Nomeadamente, as MScs quando cultivadas em substratos com rigí
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Chang, Yu-Jen, and 張育甄. "Characterization of Multipotent Mesenchymal Stem Cells Derived from Human Bone Marrow, Umbilical Cord Blood, Amniotic Fluid and Amniotic Membrane." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/84214814075223769489.

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博士<br>國立交通大學<br>生物科技系所<br>94<br>Abstract During human entire lifespan, from fetus to adult, mesenchymal stem cells (MSCs) proliferate and differentiate into mesenchyme-lineage tissues. Bone marrow and umbilical cord blood are reported to be the main sources of MSCs and have been proposed for possible clinical applications. This study evaluates the tendency in bone marrow-derived MSCs (bmMSCs) and cord blood-derived MSCs (cbMSCs) by in vitro induction and quantification of their characteristics. Results indicated that cbMSCs had a significantly stronger osteogenic potential but less capacity i
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Book chapters on the topic "Human Umbilical Cord Matrix-Derived Mesenchymal Cells"

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Bieback, Karen, and Philipp Netsch. "Isolation, Culture, and Characterization of Human Umbilical Cord Blood-Derived Mesenchymal Stromal Cells." In Mesenchymal Stem Cells. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-3584-0_14.

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Can, Alp, and Deniz Balci. "Isolation, Culture, and Characterization of Human Umbilical Cord Stroma-derived Mesenchymal Stem Cells." In Mesenchymal Stem Cell Assays and Applications. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-60761-999-4_5.

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Kadam, Sachin, Vijayendran Govindasamy, and Ramesh Bhonde. "Generation of Functional Islets from Human Umbilical Cord and Placenta Derived Mesenchymal Stem Cells." In Somatic Stem Cells. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-815-3_17.

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Kress, Sonja, Anne Neumann, Tim Hatlapatka, Antonina Lavrentieva, and Cornelia Kasper. "Expansion of Mesenchymal Stem Cells Derived from Umbilical Cord in Media Containing Human Serum (Method)." In Stem Cells and Cancer Stem Cells, Volume 9. Springer Netherlands, 2012. http://dx.doi.org/10.1007/978-94-007-5645-8_2.

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Ridzuan, Noridzzaida, Darius Widera, and Badrul Hisham Yahaya. "Isolation and Characterization of Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells." In Methods in Molecular Biology. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-1979-7_18.

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Moretti, Pierre, Tim Hatlapatka, Dana Marten, et al. "Mesenchymal Stromal Cells Derived from Human Umbilical Cord Tissues: Primitive Cells with Potential for Clinical and Tissue Engineering Applications." In Bioreactor Systems for Tissue Engineering II. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/10_2009_15.

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Dao, Thuy Thi-Thanh, Chau Thi-Hong Nguyen, Ngoc Bich Vu, Ha Thi-Ngan Le, Phuc Dang-Ngoc Nguyen, and Phuc Van Pham. "Evaluation of Proliferation and Osteogenic Differentiation of Human Umbilical Cord-Derived Mesenchymal Stem Cells in Porous Scaffolds." In Advances in Experimental Medicine and Biology. Springer International Publishing, 2019. http://dx.doi.org/10.1007/5584_2019_343.

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Van Pham, Phuc, and Ngoc Kim Phan. "Production of Good Manufacturing Practice-Grade Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells for Therapeutic Use." In Methods in Molecular Biology. Springer New York, 2014. http://dx.doi.org/10.1007/7651_2014_125.

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Oktaviono, Yudi Her, Ferry Sandra, Suryo Ardi Hutomo, et al. "The Effect of Human Umbilical Cord Blood- Mesenchymal Stem Cells-Derived Secretome on the Proliferation and Migration of Endothelial Progenitor Cells." In 8th European Medical and Biological Engineering Conference. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-64610-3_70.

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Li, Guo, Xiao-Ai Zhang, Hua Wang, et al. "Comparative Proteomic Analysis of Mesenchymal Stem Cells Derived from Human Bone Marrow, Umbilical Cord and Placenta: Implication in the Migration." In Advances in Experimental Medicine and Biology. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4614-0254-1_5.

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Conference papers on the topic "Human Umbilical Cord Matrix-Derived Mesenchymal Cells"

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Singh, Anula Divyash, Sreekanth Patnam, Aravind Kumar Rengan, and Sasidhar Venkata Manda. "Immunomodulatory Roles of Extracellular Vesicles Secreted from Human Umbilical Cord-Derived Mesenchymal Stem Cells." In 2022 E-Health and Bioengineering Conference (EHB). IEEE, 2022. http://dx.doi.org/10.1109/ehb55594.2022.9991734.

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Her Oktaviono, Yudi, Ilma Alfia Isaridha, Ferry Sandra, Achmad Lefi, and Agus Subagjo. "Ramiprilat Effects on Endothelial Progenitor Cells Migration is Increased by Human Umbilical Cord Blood-Mesenchymal Stem Cells derived Secretome." In ICBBE '20: 2020 7th International Conference on Biomedical and Bioinformatics Engineering. ACM, 2020. http://dx.doi.org/10.1145/3444884.3444914.

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Ma, Dan, Ke Xu, Gailian Zhang, et al. "AB0133 HUMAN UMBILICAL CORD-DERIVED MESENCHYMAL STEM CELLS AMELIORATE COLLAGEN-INDUCED ARTHRITIS VIA IMMUNOMODULATORY EFFECT ON T LYMPHOCYTES." In Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019. BMJ Publishing Group Ltd and European League Against Rheumatism, 2019. http://dx.doi.org/10.1136/annrheumdis-2019-eular.5651.

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He, Ping. "AB0291E THE EFFECT OF HUMAN UMBILICAL CORD MESENCHYMAL STEM CELLS-DERIVED EXOSOMES ON CHEMOKINES IN COLLAGEN-INDUCED ARTHRITIS RATS." In Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019. BMJ Publishing Group Ltd and European League Against Rheumatism, 2019. http://dx.doi.org/10.1136/annrheumdis-2019-eular.7165.

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Liu, Hua, Zhiping Qu, Shanhui Sun, et al. "Intravenous injection of human umbilical cord-derived mesenchymal stem cells for the treatment of sudden sensorineural hearing loss: a case report." In International Conference on Medical Engineering and Bioinformatics. WIT Press, 2014. http://dx.doi.org/10.2495/meb140611.

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Gao, Jinfang, Ke Xu, Gailian Zhang, Jian Han, Yang Liu, and Liyun Zhang. "FRI0510 THE EFFECT AND MECHANISM OF HUMAN UMBILICAL CORD MESENCHYMAL STEM CELLS-DERIVED EXOSOMES ON BONE DESTRUCTION OF COLLAGEN INDUCED ARTHRITIS RATS." In Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019. BMJ Publishing Group Ltd and European League Against Rheumatism, 2019. http://dx.doi.org/10.1136/annrheumdis-2019-eular.7325.

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Hu, X., L. Liu, Y. Wang, Y. Yu, Y. Liu, and J. Chai. "TSG-6 Secreted from Human Umbilical Cord-Derived Mesenchymal Stem Cells Attenuate Severe Burn-Induced Acute Lung Injury Via Inhibiting Inflammatory Reactions." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7242.

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Alaaeddoine, N., N. saliba, M. moussa, G. hilal, C. khalil, and G. haykal. "AB0101 Mesenchymal stem cells derived from bone marrow, umbilical cord and adipose tissue do not have the same effect on human osteoarthritic cartilage." In Annual European Congress of Rheumatology, EULAR 2018, Amsterdam, 13–16 June 2018. BMJ Publishing Group Ltd and European League Against Rheumatism, 2018. http://dx.doi.org/10.1136/annrheumdis-2018-eular.1747.

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Ohta, Naomi, Susumu Ishiguro, Atsushi Kawabata, et al. "Abstract 220: Human umbilical cord matrix-derived stem cells control tumor growth by tumor suppressor gene expression." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-220.

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Hansmann, G., E. Rog-Zielinska, M. Giera, et al. "Successful Human Umbilical Cord Mesenchymal Stem Cell-Derived Treatment of Severe Pulmonary Arterial Hypertension: In Vivo Effects and First-In-Human Application." In 55th Annual Meeting of the German Society for Pediatric Cardiology (DGPK). Georg Thieme Verlag KG, 2023. http://dx.doi.org/10.1055/s-0043-1761849.

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