Academic literature on the topic 'Humoral immune responses'

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Journal articles on the topic "Humoral immune responses"

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Stegall, Mark D., Natalie Moore, Timucin Taner, Han Li, and Patrick G. Dean. "Down-Regulating Humoral Immune Responses." Transplantation Journal 97, no. 3 (2014): 247–57. http://dx.doi.org/10.1097/tp.0b013e3182a72115.

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Jyonouchi, Harumi. "Nucleotide Actions on Humoral Immune Responses." Journal of Nutrition 124, suppl_1 (1994): 138S—143S. http://dx.doi.org/10.1093/jn/124.suppl_1.138s.

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YANG, HYUN MO. "A MATHEMATICAL MODEL TO ASSESS THE IMMUNE RESPONSE AGAINSTTRYPANOSOMA CRUZIINFECTION." Journal of Biological Systems 23, no. 01 (2015): 131–63. http://dx.doi.org/10.1142/s0218339015500084.

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A mathematical model is developed to assess humoral and cellular immune responses against Trypanosoma cruzi infection. Analysis of the model shows a unique non-trivial equilibrium, which is locally asymptotically stable, except in the case of a strong cellular response. When the proliferation of the activated CD8 T cells is increased, this equilibrium becomes unstable and a limit cycle appears. However, this behavior can be avoided by increasing the action of the humoral response. Therefore, unbalanced humoral and cellular responses can be responsible for long asymptomatic period, and the cont
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Ebersole, Jeffrey L. "Systemic Humoral Immune Responses in Periodontal Disease." Critical Reviews in Oral Biology & Medicine 1, no. 4 (1990): 283–331. http://dx.doi.org/10.1177/10454411900010040601.

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Alcántara, Patricia, and Dolores Correa. "Human humoral immune responses against Trichinella spiralis." International Journal for Parasitology 23, no. 5 (1993): 657–60. http://dx.doi.org/10.1016/0020-7519(93)90173-v.

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Vyas, Ashish Kumar, Mojahidul lslam, Garima Garg, Anirudh K. Singh, and Nirupma Trehanpati. "Humoral Immune Responses and Hepatitis B Infection." Digestive Diseases 39, no. 5 (2021): 516–25. http://dx.doi.org/10.1159/000514274.

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<b><i>Background:</i></b> Chronicity or seroclearance of hepatitis B virus (HBV) antigens is determined by the host immune responses. Current approaches to treat HBV patients are based on inhibition of replication using different antivirals (nucleoside or nucleotide analogs) as monotherapy, or along with immune modulators as combination therapy is being used worldwide for reducing the viral load. Understanding the role of immune cellular therapies with currently available treatments for persistent viral-mediated responses in HBV patients is unexplored. However, the gene
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Alam, KH Md Faisal, Mohd Harun Or Rashid, Md Azizul Haque, et al. "Humoral Immune Responses to Amebic Liver Abscess." TAJ: Journal of Teachers Association 34, no. 1 (2021): 5–8. http://dx.doi.org/10.3329/taj.v34i1.54899.

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Background: Amebic liver abscess (ALA) is an ancient parasitic disease caused by E. histolytica described first by Hippocrates. It is endemic worldwide, mainly in tropic and subtropics countries. About 50 million true E. histolytica infections and approximately 100,000 deaths occur each year globally. In Bangladesh, exact incidences of amebic liver abscess cases are not estimated, but hospital reports indicate that it is endemic. Immunity and immune responses in acute and post infections of ALA are not well understood to date. However, the understanding of immunology is essential to know disea
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Renshaw, B. R., W. C. Fanslow, R. J. Armitage, et al. "Humoral immune responses in CD40 ligand-deficient mice." Journal of Experimental Medicine 180, no. 5 (1994): 1889–900. http://dx.doi.org/10.1084/jem.180.5.1889.

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Individuals with X-linked hyper-IgM syndrome fail to express functional CD40 ligand (CD40L) and, as a consequence, are incapable of mounting protective antibody responses to opportunistic bacterial infections. To address the role of CD40L in humoral immunity, we created, through homologous recombination, mice deficient in CD40L expression. These mice exhibited no gross developmental deficiencies or health abnormalities and contained normal percentages of B and T cell subpopulations. CD40L-deficient mice did display selective deficiencies in humoral immunity; basal serum isotype levels were sig
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Zhang, Jingyao, Wenjuan Gao, Qirui Guo, et al. "Helminth Protein Vaccine Induced Follicular T Helper Cell for Enhancement of Humoral Immunity againstSchistosoma japonicum." BioMed Research International 2013 (2013): 1–10. http://dx.doi.org/10.1155/2013/798164.

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Protein vaccines combined with adjuvants have been widely used to induce immune responses, especially the humoral immune response, against molecular targets including parasites. Follicular T helper (Tfh) cells are the specialized providers of B-cell help, however, the induction of Tfh cells in protein vaccination has been rarely studied. Here, we report that theSchistosoma japonicumrecombinant protein (SjGST-32) combined with tacrolimus (FK506) augmented the induction of Tfh cells, which expressed the canonical markers CXCR5, BCL6, and IL-21, and enhanced the humoral immune responses in BALB/c
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Pollard, Andrew J., Rachel Galassini, Eileene M. Rouppe van der Voort, et al. "Humoral Immune Responses to Neisseria meningitidis in Children." Infection and Immunity 67, no. 5 (1999): 2441–51. http://dx.doi.org/10.1128/iai.67.5.2441-2451.1999.

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ABSTRACT An understanding of the nature of immunity to serogroup B meningococci in childhood is necessary in order to establish the reasons for poor responses to candidate vaccines in infancy. We sought to examine the nature of humoral immune responses following infection in relation to age. Serum bactericidal activity was poor in children under 12 months of age despite recent infection with Neisseria meningitidis. The highest levels of bactericidal activity were seen in children over 10 years of age. However, infants produced levels of total immunoglobulin G (IgG) and IgG subclass antibodies
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Dissertations / Theses on the topic "Humoral immune responses"

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Kachani, Malika. "Humoral immune responses in Theileria annulata infection." Thesis, Brunel University, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.279811.

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Stanford, Elaine Yvonne. "Humoral immune responses to pneumococcal disease and vaccination." Thesis, Manchester Metropolitan University, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.582746.

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Background: Streptococcus pneumoniae causes infections in children, older adults and the immunocompromised. This thesis investigates humoral immune responses to pneumococcal vaccination in asplenic adults, and responses to infection and vaccination in children with invasive pneumococcal disease (IPD). Methods: Pneumococal serotype-specific antibody was measured using IgG enzyme-linked immunosorbent assay (asplenic adults), multiplexed bead assays (lgG and IgA) and opsonophagocytic assay (children with IPD), and total IgG was measured using nephelometry. Results: Seven-valent pneumococcal conju
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Hughes, Susan Elizabeth. "Protective humoral immune responses against ovine abortifacient Chlamydia psittaci." Thesis, University of Edinburgh, 1998. http://hdl.handle.net/1842/29811.

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Breakdown of a native chlamydial vaccine against ovine enzootic abortion (OEA), coupled with the identification of the protective capacity of the major outer membrane protein (MOMP) of <I>C. psittaci, </I>has encouraged research into the use of recombinant forms of MOMP in a third generation OEA vaccine. The prospect of testing all recombinant forms of MOMP in pregnant sheep trials is a daunting one, both in terms of time and money. To circumvent these problems, it was decided that a model system would be required to assess the efficacies of recombinant MOMP constructs. The initial model devel
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Littler, Rebecca Mary. "Humoral gut mucosal immune responses in the German shepherd dog." Thesis, Royal Veterinary College (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269983.

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Bourboulia, Dimitra. "Humoral and cellular immune responses against Kaposi's sarcoma-associated herpesvirus (KSHV)." Thesis, University College London (University of London), 2004. http://discovery.ucl.ac.uk/1446705/.

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Kaposi's sarcoma-associated herpesvirus (KSHV) is the 8th human herpesvirus discovered in 1994. After primary infection, KSHV establishes latency and, in the context of immunosuppression, has been associated with specific malignancies: Kaposi's sarcoma (KS), primary effusion lymphoma (PEL) and multicentric Castleman's disease (MCD). Seroepidemiological surveys suggest that KSHV is not a ubiquitous virus and several transmission routes and risk factors must exist to explain its global distribution. The increased risk of KSHV-associated cancers in human immunodeficiency virus (HIV)-infected indi
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Dam, Noémie Thi Nhu Quynh. "Allogeneic cardiac stem/progenitor cells and innate immune and humoral responses." Thesis, Sorbonne Paris Cité, 2018. http://www.theses.fr/2018USPCC251.

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Dans une société vieillissante, les maladies cardiovasculaires comme l’infarctus du myocarde représentent un challenge pour le système de santé. Les cellules souches, qui ont le potentiel de régénérer/réparer les organes tout au long de notre vie, constituent un traitement thérapeutique prometteur. Les stratégies qui ont utilisé des cellules autologues se sont heurtées à des limites que n’ont pas les cellules allogéniques mais leur immunogénicité peut constituer un obstacle à leur utilisation. Notre objectif a été d’étudier l’interaction des cellules souches/progéniteurs cardiaques humaines (h
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Angwin, Catherine-Jane. "ANALYSIS OF HUMORAL IMMUNE RESPONSES IN HORSES WITH EQUINE PROTOZOAL MYELOENCEPHALITIS." UKnowledge, 2017. http://uknowledge.uky.edu/gluck_etds/30.

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Equine protozoal myeloencephalitis (EPM), caused by the protozoan parasite Sarcocystis neurona, is one of the most important neurological diseases of horses in the Americas. While seroprevalence of S. neurona in horses is high, clinical manifestation of EPM occurs in less than 1% of infected horses. Factors governing the occurrence and severity of EPM are largely unknown, although horse immunity might play an important role in clinical outcome. We hypothesize that EPM occurs due to an aberrant immune response, which will be discernable in the equine IgG subisotypes a, b, and (T) that recognize
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Karagiannis, Panagiotis. "Dissecting humoral immune responses in melanoma and the design of antibody immunotherapy." Thesis, King's College London (University of London), 2014. https://kclpure.kcl.ac.uk/portal/en/theses/dissecting-humoral-immune-responses-in-melanoma-and-the-design-of-antibody-immunotherapy(1b263e41-dedd-4d98-a045-97bfd6fa6f0b).html.

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Antibodies against melanoma antigens have been detected in patients but, despite known regulatory and activatory functions attributed to humoral immunity, the roles of B cells in solid tumours such as melanoma are inadequately understood. Insights into humoral responses and mechanisms of tumour-induced immune escape may in-form the design of more effective antibodies. The aims of this thesis are three-fold: a) to gain insights into regulatory mechanisms in tumour microenvironments that influence antibody expression; b) to examine whether humoral immune responses are associated with clinical ou
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Provine, Nicholas Mcdermott. "CD4 T Cells Regulate Adenovirus Vector-Elicited Cellular and Humoral Immune Responses." Thesis, Harvard University, 2016. http://nrs.harvard.edu/urn-3:HUL.InstRepos:26718733.

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The processes that regulate viral vector vaccine-elicited cellular and humoral immune responses remain poorly defined. Thus, in this thesis, the role of CD4+ T cells – master regulators of adaptive immunity – in modulating adenovirus (Ad) vector-elicited cytotoxic CD8+ T cell responses and transgene-specific antibody responses was investigated. CD4+ T cell help is critical for the induction of CD8+ T cell and antibody responses, but the mechanisms and timing of help to each of these two arms of the immune system are distinct. CD4+ T cell help is required immediately and continuously for one we
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Meshi, Abdullah Ahmed. "Characterisation of humoral immune responses to Rhd blood group antigen-derived synthetic peptides." Thesis, University of Aberdeen, 2012. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=186873.

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The aim of this project was to characterise the humoral immune responses to RhD-derived synthetic peptides as a first step towards developing alternative peptide immunogens to replace RBC in immunising donors for anti-D IgG antibody production for clinical use. In the first part, 4 peptides (Dp6, Dp13, Dp17, and Dp28) containing Th-cell epitopes on the RhD protein were used to stimulate PBMC from 2 D-alloimmunised donors in vitro. A mixture of the four peptides was also utilised to boost HLA-DR15 transgenic mice previously immunised with purified RhD protein. The ability of the four peptides t
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Books on the topic "Humoral immune responses"

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Kachani, Malika. Humoral immune responses in theileria annulata infection. Brunel University, 1990.

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Manser, Tim, ed. Specialization and Complementation of Humoral Immune Responses to Infection. Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-73900-5.

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Allen, Stephen John. An epidemiological study of humoral and cell-mediated immune responses to defined plasmodium falciparum vaccine candidate antigens and their role in protection against infection in a rural area of The Gambia. University of Birmingham, 1991.

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Hassan, Jubril Olugbenga. Some aspects of humoral and cellular immune response to 'Salmonella typhimurium' in chickens. University of Birmingham, 1989.

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Manser, Tim. Specialization and Complementation of Humoral Immune Responses to Infection. Springer, 2008.

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Various and Tim Manser. Specialization and Complementation of Humoral Immune Responses to Infection. Springer, 2010.

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Tim, Manser, ed. Specialization and complementation of humoral immune responses to infection. Springer, 2007.

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Devlin, Hugh, and Rebecca Craven. Immune system. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198759782.003.0011.

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The immune system in relation to dentistry is the topic of this chapter. Non-specific body defences are explored. Then follows specific body defences, humoral and cell mediated responses; antibody types and their mechanisms of action and the clinical application in immunization. Inflammation, both acute and chronic, is explored in relation to infections of dental origin and their complications. Problems with the immune system and hypersensitivity follow. Normal oral flora and dental plaque and the body’s response in periodontal inflammation are explored. The final section deals with the implic
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Bhole, Malini. Hypersensitivity diseases. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0300.

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Hypersensitivity reactions are aberrant immune responses that are provoked by innocuous extrinsic or self-antigens, are mediated by B-cells or T-cells, and may result in tissue or organ damage. Coombs and Gell classified hypersensitivity reactions into four types, based on the different immune responses: type I, or immediate hypersensitivity; type II, or antibody-mediated (humoral) cytotoxicity; type III, or immune-complex disease; and type IV, or delayed hypersensitivity. This chapter reviews the clinical features, diagnosis, and management of hypersensitivity reactions.
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Roxburgh, Campbell S. D., and Donald C. McMillan. Cancer, immunity, and inflammation. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199656103.003.0012_update_001.

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The chapter focuses on the role of immunity and inflammation in established cancer. From the evidence reviewed it is clear that immune and inflammatory responses, innate, humoral and adaptive, local and systemic, are intimately linked to the tumour and themselves and impact on cancer survival. It is also possible to identify key mediators that may be targeted in the cancer patient. However, further work is required to elucidate the mechanisms by which these immune and inflammatory responses are activated, maintained, and interact. Therapeutic intervention using non-selective anti-inflammatory
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Book chapters on the topic "Humoral immune responses"

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Land, Walter Gottlieb. "Humoral Innate Immune Effector Responses." In Damage-Associated Molecular Patterns in Human Diseases. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-78655-1_23.

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Mensdorff-Pouilly, Silvia, Claus Vennegoor, and Joseph Hilgers. "Detection of Humoral Immune Responses to Mucins." In Glycoprotein Methods and Protocols. Humana Press, 2000. http://dx.doi.org/10.1385/1-59259-048-9:495.

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Karp, R. D. "Inducible Humoral Immune Defense Responses in Insects." In Invertebrate Immunology. Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-642-79735-4_4.

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Anderson, D. J., and J. A. Madrigal. "Variability in antisperm and antiembryonic humoral immune responses." In Future Aspects in Contraception. Springer Netherlands, 1985. http://dx.doi.org/10.1007/978-94-009-4916-4_26.

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Somasundaram, Rajasekharan, Tianqian Zhang, and Dorothee Herlyn. "Analysis of Humoral Immune Responses in Vaccine Trials." In Handbook of Cancer Vaccines. Humana Press, 2004. http://dx.doi.org/10.1007/978-1-59259-680-5_36.

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Montero-Calle, Ana, Pablo San Segundo-Acosta, María Garranzo-Asensio, Guillermo Solís-Fernández, Maricruz Sanchez-Martinez, and Rodrigo Barderas. "Phage Microarrays for Screening of Humoral Immune Responses." In Methods in Molecular Biology. Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1562-1_3.

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Ertürk-Hasdemir, Deniz, Nicholas Paquette, Kamna Aggarwal, and Neal Silverman. "Bug Versus Bug: Humoral Immune Responses in Drosophila melanogaster." In Nucleic Acids and Molecular Biology. Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-73930-2_3.

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Shroff, Khushroo E., and John J. Cebra. "Development of Mucosal Humoral Immune Responses in Germ-Free (GF) Mice." In Advances in Experimental Medicine and Biology. Springer US, 1995. http://dx.doi.org/10.1007/978-1-4615-1941-6_92.

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Middeldorp, Jaap M. "Epstein-Barr Virus-Specific Humoral Immune Responses in Health and Disease." In Epstein Barr Virus Volume 2. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-22834-1_10.

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Ishihara, K., and T. Hirano. "BST-1/CD157 Regulates the Humoral Immune Responses in vivo." In Human CD38 and Related Molecules. KARGER, 2000. http://dx.doi.org/10.1159/000058772.

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Conference papers on the topic "Humoral immune responses"

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Pandey, Sumali, Scott Hoselton, and Jane Schuh. "Cellular And Humoral Immune Responses Differ With Inhalation Of Viable And Non-Viable Aspergillus Fumigatus Spores." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a4307.

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Sheikh, Nadeem A., Corazon P. dela Rosa, Ling-Yu Kuan, et al. "Abstract 2932: Sipuleucel-T generates robust and persistent cellular and humoral immune responses - Results from the IMPACT trial." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-2932.

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Lu, Lin, Huimin Tao, Yang Xia, et al. "Abstract 4796: Cancer stem cell vaccine inhibits metastases of primary tumors and induces humoral immune responses against cancer stem cells." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-4796.

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Zhou, Pingyu. "LB1.70 Aberrant humoral immune responses in neurosyphilis: cxcl13/cxcr5 play a pivotal role for b cell recruitment to the csf." In STI and HIV World Congress Abstracts, July 9–12 2017, Rio de Janeiro, Brazil. BMJ Publishing Group Ltd, 2017. http://dx.doi.org/10.1136/sextrans-2017-053264.175.

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Karanam, Balasubramanyam, Richard Roden, Ratish Gambhira, and Subhashini Jagu. "Abstract A138: Vaccination with HPV 16 L2E6E7 with GPI-0100 adjuvant elicits protective humoral as well as cell-mediated immune responses." In Abstracts: Frontiers in Cancer Prevention Research 2008. American Association for Cancer Research, 2008. http://dx.doi.org/10.1158/1940-6207.prev-08-a138.

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Gnjatic, Sacha, Sarah Nataraj, Naoko Imai, et al. "Abstract LB-116: Strong MAGE-A3-specific humoral and cellular immune responses in multiple myeloma patients receiving MAGE-A3 protein immunotherapy and peripheral blood lymphocyte reconstitution." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-lb-116.

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KIM, SUNGBAE, KyungHae Jung, JinHee Ahn, and Jeongeun Kim. "Abstract CT414: Efficient induction of cellular and humoral immune responses by heterologous prime-boost therapeutic vaccination, involving plasmid DNA and adenoviral vector, in subjects with HER2-expressing breast cancer: Results from a phase Ib study." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-ct414.

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SHAHAF, GITIT, MICHAL BARAK, NETA ZUCKERMAN, and RAMIT MEHR. "THE HUMORAL IMMUNE RESPONSE: COMPLEXITY AND THEORETICAL CHALLENGES." In BIOMAT 2010 - International Symposium on Mathematical and Computational Biology. WORLD SCIENTIFIC, 2011. http://dx.doi.org/10.1142/9789814343435_0018.

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van Parys, Alexander, Filip Boyen, E. Verbrugghe, Bregje Leyman, Freddy Haesebrouck, and F. Pasmans. "Salmonella Typhimurium interference with the humoral immune response of pigs." In Fifth International Symposium on the Epidemiology and Control of Foodborn Pathogens in Pork. Iowa State University, Digital Press, 2011. http://dx.doi.org/10.31274/safepork-180809-576.

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Al-Khalaifah, Hanan. "HUMORAL IMMUNE RESPONSE OF HAEMOCYTES, RESPRESENTED BY NITRIC OXIDE AND PHENOL OXIDASE PRODUCTION." In 18th International Multidisciplinary Scientific GeoConference SGEM2018. Stef92 Technology, 2018. http://dx.doi.org/10.5593/sgem2018/6.2/s25.030.

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