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Relevant bibliographies by topics / Humoral immune responses / Dissertations / Theses

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Dissertations / Theses on the topic 'Humoral immune responses'

Author: Grafiati

Published: 4 June 2021

Last updated: 19 February 2022

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1

Kachani, Malika. "Humoral immune responses in Theileria annulata infection." Thesis, Brunel University, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.279811.

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2

Stanford, Elaine Yvonne. "Humoral immune responses to pneumococcal disease and vaccination." Thesis, Manchester Metropolitan University, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.582746.

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Background: Streptococcus pneumoniae causes infections in children, older adults and the immunocompromised. This thesis investigates humoral immune responses to pneumococcal vaccination in asplenic adults, and responses to infection and vaccination in children with invasive pneumococcal disease (IPD). Methods: Pneumococal serotype-specific antibody was measured using IgG enzyme-linked immunosorbent assay (asplenic adults), multiplexed bead assays (lgG and IgA) and opsonophagocytic assay (children with IPD), and total IgG was measured using nephelometry. Results: Seven-valent pneumococcal conju

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3

Hughes, Susan Elizabeth. "Protective humoral immune responses against ovine abortifacient Chlamydia psittaci." Thesis, University of Edinburgh, 1998. http://hdl.handle.net/1842/29811.

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Breakdown of a native chlamydial vaccine against ovine enzootic abortion (OEA), coupled with the identification of the protective capacity of the major outer membrane protein (MOMP) of <I>C. psittaci, </I>has encouraged research into the use of recombinant forms of MOMP in a third generation OEA vaccine. The prospect of testing all recombinant forms of MOMP in pregnant sheep trials is a daunting one, both in terms of time and money. To circumvent these problems, it was decided that a model system would be required to assess the efficacies of recombinant MOMP constructs. The initial model devel

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4

Littler, Rebecca Mary. "Humoral gut mucosal immune responses in the German shepherd dog." Thesis, Royal Veterinary College (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269983.

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5

Bourboulia, Dimitra. "Humoral and cellular immune responses against Kaposi's sarcoma-associated herpesvirus (KSHV)." Thesis, University College London (University of London), 2004. http://discovery.ucl.ac.uk/1446705/.

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Kaposi's sarcoma-associated herpesvirus (KSHV) is the 8th human herpesvirus discovered in 1994. After primary infection, KSHV establishes latency and, in the context of immunosuppression, has been associated with specific malignancies: Kaposi's sarcoma (KS), primary effusion lymphoma (PEL) and multicentric Castleman's disease (MCD). Seroepidemiological surveys suggest that KSHV is not a ubiquitous virus and several transmission routes and risk factors must exist to explain its global distribution. The increased risk of KSHV-associated cancers in human immunodeficiency virus (HIV)-infected indi

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6

Dam, Noémie Thi Nhu Quynh. "Allogeneic cardiac stem/progenitor cells and innate immune and humoral responses." Thesis, Sorbonne Paris Cité, 2018. http://www.theses.fr/2018USPCC251.

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Dans une société vieillissante, les maladies cardiovasculaires comme l’infarctus du myocarde représentent un challenge pour le système de santé. Les cellules souches, qui ont le potentiel de régénérer/réparer les organes tout au long de notre vie, constituent un traitement thérapeutique prometteur. Les stratégies qui ont utilisé des cellules autologues se sont heurtées à des limites que n’ont pas les cellules allogéniques mais leur immunogénicité peut constituer un obstacle à leur utilisation. Notre objectif a été d’étudier l’interaction des cellules souches/progéniteurs cardiaques humaines (h

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7

Angwin, Catherine-Jane. "ANALYSIS OF HUMORAL IMMUNE RESPONSES IN HORSES WITH EQUINE PROTOZOAL MYELOENCEPHALITIS." UKnowledge, 2017. http://uknowledge.uky.edu/gluck_etds/30.

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Equine protozoal myeloencephalitis (EPM), caused by the protozoan parasite Sarcocystis neurona, is one of the most important neurological diseases of horses in the Americas. While seroprevalence of S. neurona in horses is high, clinical manifestation of EPM occurs in less than 1% of infected horses. Factors governing the occurrence and severity of EPM are largely unknown, although horse immunity might play an important role in clinical outcome. We hypothesize that EPM occurs due to an aberrant immune response, which will be discernable in the equine IgG subisotypes a, b, and (T) that recognize

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8

Karagiannis, Panagiotis. "Dissecting humoral immune responses in melanoma and the design of antibody immunotherapy." Thesis, King's College London (University of London), 2014. https://kclpure.kcl.ac.uk/portal/en/theses/dissecting-humoral-immune-responses-in-melanoma-and-the-design-of-antibody-immunotherapy(1b263e41-dedd-4d98-a045-97bfd6fa6f0b).html.

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Antibodies against melanoma antigens have been detected in patients but, despite known regulatory and activatory functions attributed to humoral immunity, the roles of B cells in solid tumours such as melanoma are inadequately understood. Insights into humoral responses and mechanisms of tumour-induced immune escape may in-form the design of more effective antibodies. The aims of this thesis are three-fold: a) to gain insights into regulatory mechanisms in tumour microenvironments that influence antibody expression; b) to examine whether humoral immune responses are associated with clinical ou

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9

Provine, Nicholas Mcdermott. "CD4 T Cells Regulate Adenovirus Vector-Elicited Cellular and Humoral Immune Responses." Thesis, Harvard University, 2016. http://nrs.harvard.edu/urn-3:HUL.InstRepos:26718733.

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The processes that regulate viral vector vaccine-elicited cellular and humoral immune responses remain poorly defined. Thus, in this thesis, the role of CD4+ T cells – master regulators of adaptive immunity – in modulating adenovirus (Ad) vector-elicited cytotoxic CD8+ T cell responses and transgene-specific antibody responses was investigated. CD4+ T cell help is critical for the induction of CD8+ T cell and antibody responses, but the mechanisms and timing of help to each of these two arms of the immune system are distinct. CD4+ T cell help is required immediately and continuously for one we

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10

Meshi, Abdullah Ahmed. "Characterisation of humoral immune responses to Rhd blood group antigen-derived synthetic peptides." Thesis, University of Aberdeen, 2012. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=186873.

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The aim of this project was to characterise the humoral immune responses to RhD-derived synthetic peptides as a first step towards developing alternative peptide immunogens to replace RBC in immunising donors for anti-D IgG antibody production for clinical use. In the first part, 4 peptides (Dp6, Dp13, Dp17, and Dp28) containing Th-cell epitopes on the RhD protein were used to stimulate PBMC from 2 D-alloimmunised donors in vitro. A mixture of the four peptides was also utilised to boost HLA-DR15 transgenic mice previously immunised with purified RhD protein. The ability of the four peptides t

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11

Walsh, Elizabeth A. "Humoral immune responses to the human hookworm Necator americanus in an endemic population." Thesis, University of Nottingham, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.294619.

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12

Bandawe, Gama Petulo. "Understanding the interplay between HIV-1 diversity, humoral immune responses and viral fitness." Doctoral thesis, University of Cape Town, 2014. http://hdl.handle.net/11427/8689.

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Includes bibliographical references.<br>HIV-1 antibody dependent cell cytotoxicity (ADCC) and neutralizing antibody (nAb) responses are both thought to be important responses to elicit through vaccination. This thesis characterises neutralizing response in two cohorts in Africa, and in a detailed study of one individual, elucidates the interplay between ADCC and nAb responses in early infection, and the impact of humoral escape on viral fitness. It remains an open question whether different geographically distinct population groups vary in their neutralization responses to HIV-1. We compared n

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Akca, Atila. "Cytokine, cellular and humoral immune responses in calves experimentally-infected with Fasciola hepatica." Thesis, University of Liverpool, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366435.

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14

Nilsson, Charlotta. "HIV-2 and SIV vaccine studies in macaques : with emphasis on humoral immune responses /." Stockholm, 2001. http://diss.kib.ki.se/2001/91-628-4771-6/.

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15

Novak, Susan Marie. "Gastrointestinal cellular and humoral immune responses in BALB/c mice infected with Cryptosporidium parvum." Diss., The University of Arizona, 1991. http://hdl.handle.net/10150/185563.

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Immunohistochemical analysis of intestinal tissue from infected and uninfected neonatal mice was performed to determine immune responsiveness to Cryptosporidium parvum at the gut level. Infected mice showed a significant increase in T cell (T helper/T cytotoxic/suppressor) populations (p < 0.001), macrophages (p < 0.001), IL-2R positive cells (p < 0.001 at 16 days PI), and IgA positive cells (p < 0.001 at 16 days PI) compared to control (uninfected) animals. No differences between the two groups of animals existed for B cell populations of the IgG (p = 0.264) and IgM (p = 0.646) isotype. Cellu

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Bautista-López, Norma Leticia. "A comparison between humoral and cellular immune responses following measles vaccination in two different settings." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0029/NQ64510.pdf.

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17

Lindroth, Karin. "Maturation of humoral immune responses : Studies on the effects of antigen type, apoptosis and age." Doctoral thesis, Stockholm : Wenner-Grens institut, Univ, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-85.

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18

Pheiffer, Carmen. "Investigation of Mycobacterium tuberculosis protein expression and analysis of humoral immune responses of TB patients." Thesis, Stellenbosch : Stellenbosch University, 2004. http://hdl.handle.net/10019.1/49999.

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Thesis (PhD)--Stellenbosch University, 2004.<br>ENGLISH ABSTRACT: New agents for the diagnosis, prevention and treatment of tuberculosis are urgently required. Yet, despite extensive tuberculosis research over recent years, no new drugs, vaccines or diagnostics have been identified to date. It is widely speculated that the major obstacle to the identification of new therapies is the lack of understanding of the hostpathogen interaction. This study has investigated whether patterns of antigen expression correlate with molecular epidemiological data and strain virulence through the analys

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19

Shahin, Abeer. "Investigation of the humoral and cellular immune responses of chickens to Salmonella typhimurium live vaccine." Diss., lmu, 2005. http://nbn-resolving.de/urn:nbn:de:bvb:19-31626.

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Abdukalykova, Saule. "Cellular and humoral immune responses in birds fed different levels of Arginine and vitamin E." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=100753.

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The effects of vitamin E (VE) and Arginine (ARG) on humoral and cellular immunity in chickens were investigated in two experiments. The humoral immunity was measured by antibody responses to sheep red blood cells (SRBC) and maternal antibody titers to the infectious bursal disease virus (IBDV), while the cellular immunity was studied using the cutaneous basophil hypersensitivity test to phytogemagglutinin (PHA) and by counting subpopulations of T-lymphocytes. We used two levels of ARG: normal (NARG, 1.2% in feed) and high ARG (HARG, additional 0.3% in drinking water or 1% in feed in experiment

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21

Mineo, Tiago Wilson Patriarca. "Estudo da resposta imune celular e humoral de cães frente à infecção oral por Neospora caninum /." Jaboticabal : [s.n.], 2007. http://hdl.handle.net/11449/104639.

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Orientador: Rosangela Zacarias Machado<br>Banca: Solange Maria Gennari<br>Banca: Aramis Augusto Pinto<br>Banca: Deise Aparecida de Oliveira Silva<br>Banca: Ana Patricia Yatsuda Natsui<br>Resumo: Neospora caninum é um protozoário do Filo Apicomplexa, que foi primeiramente descrito como causa de encefalomielite em filhotes caninos sorologicamente negativos para Toxoplasma gondii. Estudos anteriores neste importante hospedeiro da cadeia epidemiológica de N. caninum demonstram que as respostas de anticorpos IgG são tardiamente detectadas e que a infecção clínica é de difícil indução. Desta forma,

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22

Stein, Melissa Marie. "Humoral and T cell immune responses to model antigen delivered with biomaterials used in tissue engineering." Thesis, Georgia Institute of Technology, 2002. http://hdl.handle.net/1853/20175.

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23

Fulton, Jonathan Reid. "Intestinal and systemic cytotoxic T lymphocyte and humoral immune responses to oral and parenteral reovirus infection." Morgantown, W. Va. : [West Virginia University Libraries], 2006. https://eidr.wvu.edu/etd/documentdata.eTD?documentid=4474.

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Thesis (Ph. D.)--West Virginia University, 2006.<br>Title from document title page. Document formatted into pages; contains xi, 288 p. : ill. Vita. Includes abstract. Includes bibliographical references.

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Mukherjee, Paramita. "Tumor necrosis factor receptor gene therapy influences humoral and cellular immune responses in collagen induced arthritis." Connect to online resource - WSU on-site and authorized users, 2003.

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25

Beebe, Melanie Jo. "Peptide vaccine development for the human T-Lymphotropic virus type 1 : elicitation of humoral immune responses /." The Ohio State University, 2000. http://rave.ohiolink.edu/etdc/view?acc_num=osu1488203158827912.

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Mineo, Tiago Wilson Patriarca [UNESP]. "Estudo da resposta imune celular e humoral de cães frente à infecção oral por Neospora caninum." Universidade Estadual Paulista (UNESP), 2007. http://hdl.handle.net/11449/104639.

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Made available in DSpace on 2014-06-11T19:33:26Z (GMT). No. of bitstreams: 0 Previous issue date: 2007-03-15Bitstream added on 2014-06-13T19:23:20Z : No. of bitstreams: 1 mineo_twp_dr_jabo.pdf: 3433348 bytes, checksum: fac62f81f1b33434ac64c0e811ae8d5a (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>Neospora caninum é um protozoário do Filo Apicomplexa, que foi primeiramente descrito como causa de encefalomielite em filhotes caninos sorologicamente negativos para Toxoplasma gondii. Estudos anterio

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27

Tsang, Jovian. "The Biology and Interplay of Immunotherapy by Leukemia-Oncolytic Virus (iLOV) Immune Responses." Thesis, Université d'Ottawa / University of Ottawa, 2014. http://hdl.handle.net/10393/31873.

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Oncolytic viruses (OVs) are novel biological agents that selectively infect and kill malignant cells. OVs can also generate anti-cancer immunity. Our lab exploited this phenomenon and developed an in vitro vaccine with infected leukemia cells with oncolytic virus vaccine – and named immunotherapy by leukemia-oncolytic virus (iLOV) – that provided in vivo protection in a murine model for acute lymphoblastic leukemia. This work further characterizes iLOV biology and the interaction of its immune responses. An in vitro immune response assay was optimized to detect and quantify the in vivo anti-le

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Tran, Mai Hue. "Investigations of humoral and cellular immune responses directed against MUCI epithelial mucin in ovarian and breast carcinoma /." St. Lucia, Qld, 2002. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe17997.pdf.

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29

Zacharias, Zeb Ralph. "Induction and maintenance of diverse humoral and cellular immune responses following influenza A virus infection and vaccination." Diss., University of Iowa, 2018. https://ir.uiowa.edu/etd/6669.

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Influenza A virus (IAV) is a major cause of serious respiratory illness worldwide, leading to approximately 5 million severe cases and 500,000 deaths per year. Given the disease severity, associated economic costs, and recent appearance of novel IAV strains, there is a renewed interest in developing novel and efficacious “universal” IAV vaccination strategies as well as therapeutic remedies. Previous studies from our laboratory have concentrated on IAV-specific CD8 T cell-mediated protection against IAV infection as IAV-specific CD8 T cells are needed for efficient clearance of virus. Recent s

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BARRETO, Andreia Cunha. "Evaluation of humoral and cellular immune responses to P.berghei-based whole-sporozoite malaria vaccination in rhesus macaques." Master's thesis, Instituto de Higiene e Medicina Tropical, 2019. http://hdl.handle.net/10362/97490.

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A malária é uma doença infecciosa transmitida por mosquitos que continua a ser uma das doenças infecciosas mais impactantes do mundo, matando milhares de pessoas todos os anos. Apesar de todos os esforços para controlar esta doença, como quimioprofilaxia e medidas de controlo de vetores, a falta de conhecimento sobre as respostas imunes desencadeadas pelo parasita Plasmodium dificulta o desenvolvimento de uma vacina eficaz contra a malária, que é necessária com urgência. A natureza assintomática e altamente imunogénica do estadio hepático da infecção por Plasmodium torna-o num alvo ideal para

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31

Ajua, Anthony Verfasser], and Peter [Akademischer Betreuer] [Kremsner. "Characterization of Humoral Immune Responses to Two Subunit Malaria Vaccine Candidates in Humans / Anthony Ajua ; Betreuer: Peter Kremsner." Tübingen : Universitätsbibliothek Tübingen, 2015. http://d-nb.info/1163396966/34.

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32

Vu, Chi Hai [Verfasser]. "Human humoral and cellular immune responses to Staphylococcus aureus lipoproteins and Panton-Valentine Leukocidin (PVL) / Chi Hai Vu." Greifswald : Universitätsbibliothek Greifswald, 2016. http://d-nb.info/1103474162/34.

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Ajua, Anthony [Verfasser], and Peter [Akademischer Betreuer] Kremsner. "Characterization of Humoral Immune Responses to Two Subunit Malaria Vaccine Candidates in Humans / Anthony Ajua ; Betreuer: Peter Kremsner." Tübingen : Universitätsbibliothek Tübingen, 2015. http://d-nb.info/1163396966/34.

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34

Pearce, Emma St Clair. "Development of antibodies and characterisation of the humoral immune responses in a surrogate animal model for hepatitis C virus (HCV)." Thesis, Queen Mary, University of London, 2017. http://qmro.qmul.ac.uk/xmlui/handle/123456789/25978.

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Hepatitis C virus (HCV) infection has become a global public health concern with over 130 million people chronically infected and over 350,000 deaths every year from HCV-related liver diseases. GB virus-B (GBV-B) infection in tamarins is a surrogate model for acute HCV infection. Whilst HCV infection commonly leads to chronicity, GBV-B is naturally cleared. To better understand this natural clearance, this project aimed to study the associated humoral immune response to GBV-B. Additionally, GBV-B-specific antibodies were produced with the aim of characterising the pathology of the virus. Previ

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Rahman, Bhuiyan Taufiqur. "Humoral and cellular immune responses to Helicobacter pylori in Bangladeshi children and adults that may be related to protection /." Götborg : Department of Microbiology and Immunology, Institute of Biomedicine at Sahlgrenska Academy, University of Gotheburg, 2010. http://hdl.handle.net/2077/21536.

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Mutungi, Evans Mulandi. "Humoral immune responses against novel recombinant replication-competent poxvirus candidate vaccines expressing full length and chimeric lyssavirus glycoprotein genes." Diss., University of Pretoria, 2011. http://hdl.handle.net/2263/31290.

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Rabies is a neurological disease caused by viruses of the genus Lyssavirus belonging to the family Rhabdoviridae and order Mononegavirales. The Lyssavirus genus consists of eleven species namely rabies virus; Lagos bat virus; Mokola virus , Duvenhage virus; European bat lyssavirus virus type 1; European bat lyssavirus type 2; Australian bat lyssavirus; Aravan; Khujand; Irkut; West Caucasian bat viruses and recently isolated Shimoni bat virus. The prototype virus of the Lyssavirus genus is represented by rabies virus. The remaining lyssaviruses are collectively denoted as rabies-related viruses

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Stevens, Laura Joy. "THE UPTAKE OF PARTICULATE ANTIGEN BY SPECIALIZED EPITHELIUM IN THE BURSA OF FABRICIUS AND THE GENERATION OF HUMORAL IMMUNE RESPONSES." OpenSIUC, 2017. https://opensiuc.lib.siu.edu/theses/2151.

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The bursa of Fabricius is a central lymphoid organ essential for B cell development and generation of humoral immune responses in birds. The bursa is connected dorsally to the cloaca and continually “samples” the intestinal fluid phase for the presence of antigen. It is comprised of folds or plicae, which are seeded with individual follicles, where antigen processing and presentation occurs for B cell development as well as generation of antibody responses. The plicae are separated from the bursal lumen by interfollicular epithelium (IFE) and specific regions of follicle-associated epithelium

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Hennerici, Tina [Verfasser], and Rüdiger [Akademischer Betreuer] Eming. "Characterization of cellular and humoral immune responses in pemphigus patients and an HLA-transgenic mouse model / Tina Hennerici ; Betreuer: Rüdiger Eming." Marburg : Philipps-Universität Marburg, 2017. http://d-nb.info/1129358232/34.

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Nieto, Blanco David. "Torque teno sus viruses: pathogenesis in co-infection with Porcine circovirus type 2 and humoral immune responses during natural infection of pigs." Doctoral thesis, Universitat Autònoma de Barcelona, 2015. http://hdl.handle.net/10803/327879.

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Los Torque teno sus viruses pertenecen a la familia Anelloviridae, e infectan tanto a cerdos como a jabalíes. En la actualidad, los TTSuVs se dividen en dos géneros, Iotatorquevirus para los TTSuV1, que incluye las especies: TTSuV1a y TTSuV1b; y Kappatorquevirus para los TTSuV2, que incluye las especies: TTSuVk2a y TTSuVk2b. Ambos géneros se caracterizan por tener una organización similar del genoma y por una gran variabilidad genética. Las consecuencias de la infección de los TTSuVs sobre su hospedador no son del todo claras. Ambos géneros se detectan con una prevalencia muy alta, tanto en p

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Azizi, Ali. "Humoral and cellular immune responses in RNA viral infections: Immunogenicity of HIV-1, HCV and SARS-CoV candidate vaccines in animal models." Thesis, University of Ottawa (Canada), 2006. http://hdl.handle.net/10393/29278.

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It is difficult to induce protective immunity against most RNA viruses. However, there is strong evidence that humoral and especially cellular immune responses play crucial roles in the control of established RNA viral infections. Thus, an ideal vaccine should be able to induce strong specific antibody titer as well as a robust T-helper and T-cell cytotoxic response. Here, correlates of protective immunity against HIV-1, HCV and SARS-CoV were assessed. Monocistronic and polycistronic DNA constructs containing structural HIV-l, and SARS genes were designed. The structural proteins (HIV- gpl20,

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Sirskyj, Danylo. "The Requirement of Toll-like Receptor Signaling in the Induction of Humoral and Cell-mediated Immune Responses to the Orally Administered Dukoral® Vaccine." Thèse, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/23630.

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Only a limited number of orally-administered vaccines have been licensed, such as the Dukoral vaccine, comprised of killed whole-cell Vibrio cholerae and cholera toxin B subunit (CTB). Thus far, mechanistic details underlying the resulting protective immune generated by this vaccine, including the requirement of Toll-like receptor (TLR) signaling, remain largely unknown. Herein, I investigated the involvement of TLR signaling in the induction of humoral immune responses following oral and intramuscular immunization with Dukoral or its components by using TLR-2-, TLR-4-, MyD88- and Trif-deficie

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Quddos, Fatima. "The Effect Of Slow Release Cortisol Implant On Humoral Immune Responses And Infection Prevalence Following Experimental Challenge With Flavobacterium Psycrophilum In Rainbow Trout (Oncorhynchus Mykiss)." W&M ScholarWorks, 2020. https://scholarworks.wm.edu/etd/1616444450.

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Pacific salmon migrate long distances to spawn as part of their life cycle. During this journey from sea to their natal stream, they undergo major endocrine, physiological and immune changes. Cortisol, the primary stress hormone, gradually increases during the journey. Persistent high cortisol levels have deleterious health effects, including suppression of the antibody response. However, pathogens encountered during their journey may stimulate antibody responses to overcome the infection. My main research question focuses on how salmonids balance the immunosuppressive effects of high cortisol

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El, Sayed Rania. "ROLE OF FDCs AND FDC ACTIVATION IN PROMOTING HUMORAL IMMUNITY INCLUDING RESPONSES TO T-DEPENDENT ANTIGENS IN THE ABSENCE OF T CELLS." VCU Scholars Compass, 2009. http://scholarscompass.vcu.edu/etd/1927.

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Follicular dendritic cells (FDCs) reside in primary B-cell follicles and in the light zones of germinal centers (GCs) in secondary follicles, where their dendrites interdigitate forming extensive networks intimately interacting with B-cells. In GCs, FDCs can be found at the edges attached to the supporting reticular fibers. They trap and arrange immune complexes (ICs) in vivo and in vitro in a periodic manner with 200–500Å spacing and provide both antigen-specific and non-specific accessory signals to B-cells. FDCs exist in resting and activated states, with two characteristically different ph

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Nissinen, A. (Antti). "Humoral immune response to phosphatidylethanol." Doctoral thesis, Oulun yliopisto, 2011. http://urn.fi/urn:isbn:9789514295232.

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Abstract Heavy alcohol consumption places a substantial burden on health all over the world. Metabolites of alcohol evoke alterations that lead to tissue damage in many organs. Phosphatidylethanol (PEth) is a unique phospholipid formed in the cellular membranes during the metabolism of ethanol after alcohol consumption. PEth has attracted special attention as it is postulated to be a reliable marker of long term heavy alcohol consumption. The aims of present study were to investigate the immunogenicity of phosphatidylethanol in mice and to analyze the plasma antibodies binding to phosphatidyle

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Hamsten, Carl. "Protein based approaches to understand and prevent contagious bovine pleuropneumonia." Doctoral thesis, KTH, Proteomik, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-11108.

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Contagious bovine pleuropneumonia (CBPP) is a severe infectious disease caused by Mycoplasma mycoides subsp. mycoides small colony type (M. mycoides SC) and is a vast problem in Africa. Current CBPP prevention is based on attenuated live strain vaccines, but these are limited by factors such as short-term immunity, cold-chain dependence and retained virulence. CBPP can be diagnosed using post-mortem examination, identification of the agent using culture and PCR based methods as well as serological diagnostic methods, but the latter are generally not sensitive enough and there is also demand fo

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Barclay, W. S. "The humoral immune response to rhinovirus infection." Thesis, University of Reading, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.383380.

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Ali, Munaf. "The humoral immune response to SIV recombinant antigens." Thesis, Imperial College London, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243412.

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Kummu, O. (Outi). "Humoral immune response to carbamyl-epitopes in atherosclerosis." Doctoral thesis, Oulun yliopisto, 2014. http://urn.fi/urn:isbn:9789526205670.

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Abstract Carbamylation of proteins in vivo occurs by cyanate, non-enzymatically when urea is dissociated, and by myeloperoxidase-catalyzed oxidation from thiocyanate. Carbamylation of low-density lipoprotein is suggested to enhance atherogenesis in patients with with chronic kidney disease and uremia. This thesis study assessed the questions of whether healthy humans or uremic patients under enhanced carbamylation have antibodies recognizing carbamyl-epitopes in plasma, and what is their role in vivo. Also, humoral immune response to carbamyl-LDL immunization and its impact on atherogenesis in

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Joller, Nicole Christine. "Humoral immune response to the intracellular pathogen Legionella pneumophila /." Zürich : ETH, 2008. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=17950.

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Douthett, Rebecca L. "Enhancement of the humoral immune response to Pseudomonas aeruginosa." The Ohio State University, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=osu1126903068.

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