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Journal articles on the topic "Hybrid associate"

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Kakoulidou, Ioanna, Robert S. Piecyk, Rhonda C. Meyer, et al. "Mapping parental DMRs predictive of local and distal methylome remodeling in epigenetic F1 hybrids." Life Science Alliance 7, no. 4 (2024): e202402599. http://dx.doi.org/10.26508/lsa.202402599.

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F1 hybrids derived from a cross between two inbred parental lines often display widespread changes in DNA methylation and gene expression patterns relative to their parents. An emerging challenge is to understand how parental epigenomic differences contribute to these events. Here, we generated a large mapping panel of F1 epigenetic hybrids, whose parents are isogenic but variable in their DNA methylation patterns. Using a combination of multi-omic profiling and epigenetic mapping strategies we show that differentially methylated regions in parental pericentromeres act as major reorganizers of hybrid methylomes and transcriptomes, even in the absence of genetic variation. These parental differentially methylated regions are associated with hybrid methylation remodeling events at thousands of target regions throughout the genome, both locally (in cis) and distally (in trans). Many of these distally-induced methylation changes lead to nonadditive expression of nearby genes and associate with phenotypic heterosis. Our study highlights the pleiotropic potential of parental pericentromeres in the functional remodeling of hybrid genomes and phenotypes.
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Rey, María-Dolores, Carmen Ramírez, and Azahara C. Martín. "Wheat, Rye, and Barley Genomes Can Associate during Meiosis in Newly Synthesized Trigeneric Hybrids." Plants 10, no. 1 (2021): 113. http://dx.doi.org/10.3390/plants10010113.

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Polyploidization, or whole genome duplication (WGD), has an important role in evolution and speciation. One of the biggest challenges faced by a new polyploid is meiosis, in particular, discriminating between multiple related chromosomes so that only homologs recombine to ensure regular chromosome segregation and fertility. Here, we report the production of two new hybrids formed by the genomes of species from three different genera: a hybrid between Aegilops tauschii (DD), Hordeum chilense (HchHch), and Secale cereale (RR) with the haploid genomic constitution HchDR (n = 7× = 21); and a hybrid between Triticum turgidum spp. durum (AABB), H. chilense, and S. cereale with the constitution ABHchR (n = 7× = 28). We used genomic in situ hybridization and immunolocalization of key meiotic proteins to establish the chromosome composition of the new hybrids and to study their meiotic behavior. Interestingly, there were multiple chromosome associations at metaphase I in both hybrids. A high level of crossover (CO) formation was observed in HchDR, which shows the possibility of meiotic recombination between the different genomes. We succeeded in the duplication of the ABHchR genome, and several amphiploids, AABBHchHchRR, were obtained and characterized. These results indicate that recombination between the genera of three economically important crops is possible.
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Rey, María-Dolores, Carmen Ramírez, and Azahara C. Martín. "Wheat, Rye, and Barley Genomes Can Associate during Meiosis in Newly Synthesized Trigeneric Hybrids." Plants 10, no. 1 (2021): 113. http://dx.doi.org/10.3390/plants10010113.

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Polyploidization, or whole genome duplication (WGD), has an important role in evolution and speciation. One of the biggest challenges faced by a new polyploid is meiosis, in particular, discriminating between multiple related chromosomes so that only homologs recombine to ensure regular chromosome segregation and fertility. Here, we report the production of two new hybrids formed by the genomes of species from three different genera: a hybrid between Aegilops tauschii (DD), Hordeum chilense (HchHch), and Secale cereale (RR) with the haploid genomic constitution HchDR (n = 7× = 21); and a hybrid between Triticum turgidum spp. durum (AABB), H. chilense, and S. cereale with the constitution ABHchR (n = 7× = 28). We used genomic in situ hybridization and immunolocalization of key meiotic proteins to establish the chromosome composition of the new hybrids and to study their meiotic behavior. Interestingly, there were multiple chromosome associations at metaphase I in both hybrids. A high level of crossover (CO) formation was observed in HchDR, which shows the possibility of meiotic recombination between the different genomes. We succeeded in the duplication of the ABHchR genome, and several amphiploids, AABBHchHchRR, were obtained and characterized. These results indicate that recombination between the genera of three economically important crops is possible.
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Catling, P. M. "Carex oligospermia × Carex rostrata, a new natural hybrid in section Vesicariae from northern Ontario." Canadian Journal of Botany 74, no. 1 (1996): 91–97. http://dx.doi.org/10.1139/b96-013.

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A high level of achene sterility, nonexserted anthers, and aborted pollen support the hybrid rank of a plant of unusual morphology from the Timiskaming district in northern Ontario. While the centrally involute leaves associate the plant unquestionably with Carex oligosperma, the waxy and papillate leaf surface associate it unquestionably with Carex rostrata, and various intermediate characteristics and circumstantial evidence provide further support for this parentage and a new natural hybrid. This new taxon has pistillate scales 1.7–2.4 mm wide, intermediate in width between the lanceolate scales of C. rostrata, which are 1.3–1.6 mm wide, and the broadly triangular scales of C. oligosperma, which are 3–4 mm wide. The perigynia correspond most closely with those of C. oligosperma, but the pistillate spikes with 8–41 flowers resemble more closely those of the C. rostrata parent. Carex oligosperma × C. rostrata resembles C. vesicaria but differs in its long creeping rhizomes, narrower involute leaves, and shorter ligules. A key to Carex section Vesicariae in northern Ontario is included, as well as a description of the new hybrid. The hybrids occupied an inundated zone between a higher solid sphagnum carpet dominated by C. oligosperma and a quaking mat occupied by C. rostrata. Keywords: Carex, hybridization, systematics, morphology, Ontario, Canada.
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Yordanov, Georgi. "Popping corn, hybrid Kneja pop 1 - a new Bulgarian selection of corn for food purposes. First message." Bulgarian Journal of Crop Science 62, no. 2 (2025): 44–52. https://doi.org/10.61308/pekc5791.

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The article presents original data on the newest, high-quality, Bulgarian pop corn hybrid Kneja pop 1. The hybrid was selected at the Maize Research Institute in the city of Knezha, Bulgaria. It was created by Associate Professor Dr. Georgi Yordanov, as a result of a long-term selection and genetic program for the creation of corn hybrids for special purposes of use. In 2021. it was submitted for official state testing and recognition in the IASAS system. Hybrid popping corn Kneja pop 1 has a patent Certificate for a new plant variety, Registration No. 11298 P2 and is entered in the Official Variety List of the Republic of Bulgaria. It is characterized by very good agrobiological and economic qualities of the crop, tall, productive and vibrant plants, resistant to diseases and enemies. The popcorn obtained from the grain of the Kneja pop 1 hybrid, after heat treatment, is distinguished by a very good commercial appearance and excellent tasting qualities. The cracking coefficient, Kpop1, reaches 40 (cm3/g).
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Bossard, Cédric, Henri Granel, Yohann Wittrant, et al. "Polycaprolactone / bioactive glass hybrid scaffolds for bone regeneration." Biomedical Glasses 4, no. 1 (2018): 108–22. http://dx.doi.org/10.1515/bglass-2018-0010.

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Abstract Bioactive glasses (BG) bond to bone and stimulate bone regeneration, but they are brittle. Inorganicorganic hybrids appear as promising bone substitutes since they associate the bone mineral forming ability of BG with the toughness of polymers. Hybrids comprised of polycaprolactone (PCL) and SiO2-CaO BG were produced by sol-gel chemistry and processed into porous scaffolds with controlled pore and interconnection sizes. The obtained scaffolds are highly flexible, meaning that PCL effectively introduces toughness. Apatite formation is observed within 24 hours of immersion in simulated body fluid (SBF) and is not limited to the surface as the entire hybrid progressively changes into bone-like minerals. The degradation rate is suitable for bone regeneration with a 13.2% weight loss after 8 weeks of immersion. Primary osteoblasts cultured in scaffolds demonstrate that the samples are not cytotoxic and provide good cell adhesion. The in vivo study confirms the bioactivity, biocompatibility and suitable degradation rate of the hybrid. A physiological bone made of trabeculae and bone marrow regenerates. The structure and kinetic of bone regeneration was similar to the implanted commercial standard based on bovine bone, demonstrating that this new synthetic PCL-BG hybrid could perform as well as animal-derived bone substitutes.
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Larasati, Bethari, and Eliza Fatima. "Evaluation of the Impact of Hybrid Working on Auditors' Self-Efficacy." East Asian Journal of Multidisciplinary Research 2, no. 12 (2024): 5253–78. http://dx.doi.org/10.55927/eajmr.v2i12.7692.

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This study aims to evaluate the concept of hybrid working in Public Accounting Firms (KAP) and its impact on self-efficacy after the COVID-19 pandemic who previously worked remotely. This research was conducted using a qualitative research method. The data source of this research was carried out by distributing questionnaires with 53 respondents from associate to manager level who work at Public Accounting Firm and interviews with 5 resource persons from senior associate to manager level from Big Four and Non-Big Four Firms. The results showed that in implementing the hybrid concept, Firms has disseminated the Firms' policy, provided support, provided facilities for collaboration and focus, as well as provided flexibility in determining work schedules. Self-efficacy arising from hybrid working shows experience, expertise, confidence, motivation, and auditor performance help auditors adapt to hybrid work. For this reason, this study recommends that the hybrid working model can be continued as a new working trend of auditors in KAP. This research is still limited to auditors below manager level and does not represent all KAP in Indonesia. This research provides an understanding of the concept of hybrid working which is a new work style choice in the auditor environment by looking at the auditor's personal self-efficacy.
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Michalak, Pawel, and Daina Ma. "The acylphosphatase (Acyp) alleles associate with male hybrid sterility in Drosophila." Gene 416, no. 1-2 (2008): 61–65. http://dx.doi.org/10.1016/j.gene.2008.03.006.

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Zeng, L. W., and R. S. Singh. "A combined classical genetic and high resolution two-dimensional electrophoretic approach to the assessment of the number of genes affecting hybrid male sterility in Drosophila simulans and Drosophila sechellia." Genetics 135, no. 1 (1993): 135–47. http://dx.doi.org/10.1093/genetics/135.1.135.

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Abstract We have attempted to estimate the number of genes involved in postzygotic reproductive isolation between two closely related species, Drosophila simulans and Drosophila sechellia, by a novel approach that involves the use of high resolution two-dimensional gel electrophoresis (2DE) to examine testis proteins in parents, hybrids and fertile and sterile backcross progenies. The important results that have emerged from this study are as follows: (1) about 8% of about 1000 proteins examined showed divergence (presence/absence) between the two species; (2) by tracing individual proteins in parental, hybrid and backcross males, we were able to associate the divergent proteins with different chromosomes and found that most divergent proteins are associated with autosomes and very few with X chromosome, Y chromosome and cytoplasm; (3) when proteins showing both quantitative and qualitative differences between the two species were examined in F1 hybrid males, most (97.4%) proteins were expressed at levels between the two parents and no sign of large scale changes in spot density was observed. All the proteins observed in the two parental species were present in F1 hybrid males except two species-specific proteins that may be encoded (or regulated) by sex chromosomes; (4) when different fertile and sterile backcross male testes were compared, a few D. sechellia-specific proteins were identified to be consistently associated with male sterility. These results along with the observation that a large proportion (23.6%) of first generation backcross males were fertile show that hybrid male sterility between D. simulans and D. sechellia involves a relatively small number of genes. Role of large scale genetic changes due to general genome incompatibility is not supported. The results also suggest that the large effect of X chromosome on hybrid male sterility is not due to higher divergence of X chromosome than autosomes.
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Prazeres, Camila Segalla, and Cileide Maria Medeiros Coelho. "Osmolyte accumulation and antioxidant metabolism during germination of vigorous maize seeds subjected to water deficit." Acta Scientiarum. Agronomy 42 (April 3, 2020): e42476. http://dx.doi.org/10.4025/actasciagron.v42i1.42476.

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The objective of this work was to evaluate the alterations of antioxidant enzyme reserves and antioxidant enzymes during germination under water deficit in maize hybrids and to associate with seed vigor, determining the mechanisms related to tolerance for this stress. Two three-way maize hybrids were characterized by their vigor at different levels of water deficit induced by polyethylene glycol 6000. Next, the seeds were hydrated at different osmotic potentials (0.0, -0.3, and -0.9 MPa) and removed at different times to assess the levels of the total soluble protein, total soluble sugars, proline, starch, and antioxidant enzymes, such as superoxide dismutase, catalase and ascorbate peroxidase. The analysis of variance, Tukey test at 5% and principal component analysis (PCA) were used. The vigorous hybrid (HT1) was more efficient than the low vigor hybrid seeds (HT2) in mobilizing the total soluble protein during the initial stages of germination and the total soluble sugars before and after root protrusion under water deficit in addition to increasing the catalase activity at the different osmotic potentials that were assessed.
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Dissertations / Theses on the topic "Hybrid associate"

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Ovchinnikov, O. V., M. S. Smirnov, A. O. Dedikova, B. I. Shapiro, T. S. Shatskikh, and A. N. Latyshev. "Spectral Manifestation of Hybrid Association of Zn0.7Sd0.3S Colloidal Quantum Dots with J-Aggregates of Thiacarbocyanine Dye." Thesis, Sumy State University, 2013. http://essuir.sumdu.edu.ua/handle/123456789/35329.

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Spectral properties of mixtures of Zn0.7Sd0.3S colloidal quantum dots with mean diameter value of 3.5 nm with the molecules of 3,3'-di(γ-sulfopropil)-9-ethyl-4,5,4',5'-dibenzo-thiacarbocyanine betaine pyridine salt (DEC), prepared in gelatin were investigated. The obtained data indicated that the formation of well-luminescent trans-J-aggregates and spectral tuning in the position of the absorption band of DEC and the luminescence band of quantum dots, providing requirements for resonant energy transfer in the hybrid associate are the determinant factors in the increase of the luminescent emission of DEC molecules, interacting with Zn0.7Cd0.3S colloidal quantum dots. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/35329
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Rose, Connie. "Comparing critical thinking skills of associate degree nursing students enrolled in a hybrid design versus traditional lecture." Thesis, Northern Kentucky University, 2014. http://pqdtopen.proquest.com/#viewpdf?dispub=3622608.

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<p> <b>Background:</b> Approximately 25% of newly hired nurses are deficient in critical thinking skills. <b>Purpose:</b> The purpose of the study was to determine if the hybrid design course assisted nursing students to improve critical thinking skills as compared to the traditional face-to-face lecture. <b>Methods:</b> This quasi-experimental study utilized pre- and post-test Assessment Technologies Institute, LLC (ATI) score analyses, course grades, and a demographic survey for students in the hybrid design course and students in the traditional course. The sample size consisted of 26 students in the hybrid design course and 25 students in the traditional lecture course. <b>Results:</b> No statistically significant differences were found between the critical thinking skills of students in the hybrid design section versus the traditional lecture section of the medical-surgical course. Course grades were statistically higher in the hybrid design course when compared to the traditional lecture section of the course.</p>
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Lee, Jeong Eun. "Bayesian hybrid algorithms and models : implementation and associated issues." Thesis, Queensland University of Technology, 2010. https://eprints.qut.edu.au/33151/1/Jeong_Lee_Thesis.pdf.

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This thesis addresses computational challenges arising from Bayesian analysis of complex real-world problems. Many of the models and algorithms designed for such analysis are ‘hybrid’ in nature, in that they are a composition of components for which their individual properties may be easily described but the performance of the model or algorithm as a whole is less well understood. The aim of this research project is to after a better understanding of the performance of hybrid models and algorithms. The goal of this thesis is to analyse the computational aspects of hybrid models and hybrid algorithms in the Bayesian context. The first objective of the research focuses on computational aspects of hybrid models, notably a continuous finite mixture of t-distributions. In the mixture model, an inference of interest is the number of components, as this may relate to both the quality of model fit to data and the computational workload. The analysis of t-mixtures using Markov chain Monte Carlo (MCMC) is described and the model is compared to the Normal case based on the goodness of fit. Through simulation studies, it is demonstrated that the t-mixture model can be more flexible and more parsimonious in terms of number of components, particularly for skewed and heavytailed data. The study also reveals important computational issues associated with the use of t-mixtures, which have not been adequately considered in the literature. The second objective of the research focuses on computational aspects of hybrid algorithms for Bayesian analysis. Two approaches will be considered: a formal comparison of the performance of a range of hybrid algorithms and a theoretical investigation of the performance of one of these algorithms in high dimensions. For the first approach, the delayed rejection algorithm, the pinball sampler, the Metropolis adjusted Langevin algorithm, and the hybrid version of the population Monte Carlo (PMC) algorithm are selected as a set of examples of hybrid algorithms. Statistical literature shows how statistical efficiency is often the only criteria for an efficient algorithm. In this thesis the algorithms are also considered and compared from a more practical perspective. This extends to the study of how individual algorithms contribute to the overall efficiency of hybrid algorithms, and highlights weaknesses that may be introduced by the combination process of these components in a single algorithm. The second approach to considering computational aspects of hybrid algorithms involves an investigation of the performance of the PMC in high dimensions. It is well known that as a model becomes more complex, computation may become increasingly difficult in real time. In particular the importance sampling based algorithms, including the PMC, are known to be unstable in high dimensions. This thesis examines the PMC algorithm in a simplified setting, a single step of the general sampling, and explores a fundamental problem that occurs in applying importance sampling to a high-dimensional problem. The precision of the computed estimate from the simplified setting is measured by the asymptotic variance of the estimate under conditions on the importance function. Additionally, the exponential growth of the asymptotic variance with the dimension is demonstrated and we illustrates that the optimal covariance matrix for the importance function can be estimated in a special case.
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Tran, Kelly. "Hybride associant polymère biosourcé et un système renforçant les propriétés de tenues au feu : analyse de la morphologie des mélanges et de leur structure pour l'optimisation des propriétés fonctionnelles." Electronic Thesis or Diss., Lyon, 2021. http://www.theses.fr/2021LYSES017.

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L’objectif de ces travaux de recherche est de développer un matériau hybride biopolymère/géopolymère ayant des bonnes propriétés de résistance et de réaction au feu, mis en œuvre par un procédé continu d’extrusion. Pour cela, il a été nécessaire de mener une étude rhéocinétique afin de mieux comprendre la réaction de géopolymérisation et ainsi d’éviter les risques de réticulation dans la machine. Le principe de superposition temps de réaction – température a été introduit afin de prédire à la fois le temps de gel chimique ainsi que les modules de la pâte de géopolymère au cours de la réaction. Le modèle en série parallèle de Takayanagi a également été utilisé afin de décrire l’évolution de la structure du réseau au cours de la formation du géopolymère. L’étude de différents moyens de mise en œuvre ont été abordés et a permis de mettre en évidence un procédé permettant de combiner à la fois la fabrication du matériau hybride thermoplastique à base d’amidon thermoplastique (TPS) et la génération in situ de géopolymère dans une extrudeuse bivis. Cette thèse a abouti au développement d’un nouveau matériau hybride présentant des propriétés de résistance au feu améliorées que ce soit au niveau du flux de chaleur dégagée ou du retardement de l’ignition du matériau. La présence de géopolymère au sein de la matrice de TPS permet l’obtention d’un résidu de calcination ayant une structure alvéolaire, expansée et cohésive pouvant jouer le rôle de barrière physique à la diffusion de la chaleur<br>The objective of this research is to develop a biopolymer / geopolymer hybrid material with good fire resistance and reaction properties, obtained by a continuous extrusion process. For, it was necessary to carry out a rheokinetic study in order to better understand the geopolymerization reaction and thus to avoid the risks of crosslinking in the twin screw extruder. The principle of reaction time - temperature superposition was developed in order to predict both the setting time as well as the moduli of the geopolymer paste during the reaction. The Takayanagi parallel series model was also used to describe the evolution of the network structure during geopolymer formation. This study highlights a process allowing to combine both the processing of the thermoplastic hybrid material based on thermoplastic starch (TPS) and the generation of geopolymer in situ of a twin-screw extruder. This thesis led to the development of a new hybrid material exhibiting improved fire resistance properties either in terms of the heat release rate or the retardation of the ignition of the material. The presence of geopolymer within the TPS matrix allows the formation of a calcination residue with an alveolar, expanded and cohesive structure that can act as a physical barrier to the heat diffusion
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Shatskikh, T. S., O. V. Ovchinnikov, M. S. Smirnov, B. I. Shapiro, A. N. Latyshev, and V. Yu Khoklov. "The Photophysical Properties Investigation of Hybrid Associates of Methylene Blue Molecules with Colloidal CdS Quantum Dots and CdS / Cd(OH)2 "Core-Shell" Systems." Thesis, Sumy State University, 2013. http://essuir.sumdu.edu.ua/handle/123456789/35273.

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The spectral properties of associates of methylene blue molecules with colloidal CdS quantum dots and CdS / Cd(OH)2 «core-shell» systems were investigated. It is shown that according to env ironment methylene blue changes its photophysical properties during association. These properties are due to changes of MB structure as a result of oxidation-reduction reactions. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/35273
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Petzold, Herman E. III. "Discovery of New Protein-DNA and Protein-Protein Interactions Associated With Wood Development in Populus trichocarpa." Diss., Virginia Tech, 2017. http://hdl.handle.net/10919/89363.

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The negative effects from rising carbon levels have created the need to find alternative energy sources that are more carbon neutral. One such alternative energy source is to use the biomass derived from forest trees to fulfill the need for a renewable alternative fuel. Through increased understanding and optimization of regulatory mechanisms that control wood development the potential exists to increase biomass yield. Transcription factors (TFs) are DNA-binding regulatory proteins capable of either activation or repression by binding to a specific region of DNA, normally located in the 5-prime upstream promoter region of the gene. In the first section of this work, six DNA promoters from wood formation-related genes were screened by the Yeast One-Hybrid (Y1H) assay in efforts to identify novel interacting TFs involved in wood formation. The promoters tested belong to genes involved in lignin biosynthesis, programmed cell death, and cambial zone associated TFs. The promoters were screened against a mini-library composed of TFs expressed 4-fold or higher in differentiating xylem vs phloem-cambium. The Y1H results identified PtrRAD1 with interactions involving several of the promoters screened. Further testing of PtrRAD1 by Yeast Two-Hybrid (Y2H) assay identified a protein-protein interaction (PPI) with poplar DIVARACATA RADIALIS INTERACTING FACTOR (DRIF1). PtrDRIF1 was then used in the Y2H assay and formed PPIs with MYB/SANT domain proteins, homeodomain family (HD) TFs, and cytoskeletal-related proteins. In the second section of this work, PPIs involving PtrDRIF1s' interaction partners were further characterized. PtrDRIF1 is composed of two separate domains, an N-terminal MYB/SANT domain that interacted with the MYB/SANT domain containing PtrRAD1 and PtrDIVARICATA-like proteins, and a C-terminal region containing a Domain of Unknown Function 3755 (DUF3755). The DUF3755 domain interacted with HD family members belonging to the ancient WOX clade and Class II KNOX domain TFs. In addition, PtrDRIF1 was able to form a complex between PtrRAD1 and PtrWOX13c in a Y2H bridge assay. PtrDRIF1 may function as a regulatory module linking cambial cell proliferation, lignification, and cell expansion during growth. Combined, these findings support a role for PtrDRIF1 in regulating aspects of wood formation that may contribute to altering biomass yield.<br>Ph. D.
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Taylor, Rebecca Charlotte. "Examining the development of the associative-cognitive hybrid model in children." Thesis, University of Cambridge, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.620586.

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Hou, Deyi. "Generalised and hybrid sustainability assessments in contaminated site remediation and associated sustainable behaviour." Thesis, University of Cambridge, 2014. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708371.

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Ellendt, Sunna [Verfasser]. "Environmental and Genetic Determinants of Bacterial Microbiota and Parasites Associated with Cottus Across Natural Hybrid Zones / Sunna Ellendt." Kiel : Universitätsbibliothek Kiel, 2016. http://d-nb.info/1120409691/34.

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Kinninmonth, Malcolm Allan. "Nano-layered inorganic-organic hybrid materials for the controlled delivery of antimicrobials to protect against healthcare associated infections." Thesis, Manchester Metropolitan University, 2012. http://e-space.mmu.ac.uk/313310/.

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Healthcare associated infections (HCAI) are a significant problem facing modern healthcare settings; therefore it is important to develop strategies aimed at reducing the number of patients contracting HCAIs. This study investigates the use of essential oils (EO) as antimicrobial additives for polymer materials, including surface coatings (paints), silicone elastomer and a thermoplastic. Conferring antimicrobial properties to surfaces made from such materials, would help to reduce the number of bacteria, reduce the risk of cross infection and therefore limit the number of HCAIs. The antimicrobial efficacies of five EOs (manuka (MO), oregano (OO), rosewood (RO), lavender (LO) and geranium (GO)) were examined individually against three microorganisms associated with HCAI (MRSA, Acinetobacter baumannii, and Pseudomonas aeruginosa). Oregano oil provided the highest level of antimicrobial activity, inhibiting the growth of all three bacteria at 2.5 % (v/v). In an attempt to reduce the concentration of oil required for inhibition of growth, blends of the EO have been explored. A blend of oregano oil and rosewood oil exhibited the strongest synergistic antimicrobial effect at a ratio of 3:1, and was selected as the antimicrobial to be added to the polymer materials. EOs are volatile, direct addition to polymers may allow the EO to bloom to the surface and rapidly evaporate from the polymer, resulting in loss of antimicrobial activity. Furthermore thermoplastics are processed at high temperatures which can result in degradation of the EO. Encapsulation strategies for the EO were therefore investigated in order to promote both sustained release of the EO and protection against degradation / volatilisation during blending in to thermoplastic materials. Considering the latter in particular, inorganic adsorbents were selected and the adsorption characteristics of the EOs onto a range of natural and synthetic montmorillonite type layered silicates were investigated. Using gas chromatography and flow micro-calorimetry their suitability as controlled release reservoirs was investigated. Rockwood Additives Laponite® RD provided the highest levels of adsorption, achieving approximately 170 mg.g-1 for oregano oil and 140 mg.g-1 for rosewood oil. Organic modification (via cation exchange) of the layered silicates with alkyl ammonium surfactants did not give the anticipated increase in the level of EO adsorption from solution. However the strength of adsorption was in some cases increased. Laponite® RD with 50 % 2HT2M organic modification (modified via cation exchange using dihydrogenated tallow dimethyl ammonium chloride) was selected as the adsorption substrate for the EO based antimicrobial. Samples of linear low density polyethylene (LLDPE), silicone elastomer (SE) and a solvent based paint were formulated containing the oregano oil:rosewood oil blend pre-adsorbed onto Laponite® RD with 50 % 2HT2M organic modification. These materials were tested for antimicrobial efficacy against MRSA and A. baumannii, and the results were compared to control polymers where the EO blend had been added directly. P. aeruginosa was found to be unsuitable as a test organism for the polymer samples. All of the polymer samples containing the EO blend exhibited antimicrobial activity, with SE containing the pre-adsorbed EO blend performing the best achieving a 3 log reduction in MRSA cells. The SE and paint materials containing the preadsorbed EO blend outperformed the directly added EO controls; however the reverse was true for LLDPE. The release rates of the EO molecules from the polymers were investigated using headspace gas chromatography, and it was found that pre-adsorption of the EO onto the organically modified Laponite® RD more than doubled the time the EO molecules were retained in comparison to the directly added controls. It has been shown that EO can be used to obtain antimicrobials with broad spectrum antimicrobial activity, and that said activity can be successfully conferred onto polymer materials. Adsorption of the EO onto layered silicates before addition to polymers improved the retention of the EO molecules, thereby increasing the antimicrobial lifetime. Further work will be undertaken to optimise the EO polymer formulations, to combine the best possible antimicrobial activity with EO molecule retention that will make the materials a viable commercial product. The mechanical properties of the polymers; such as hardness, strength and toughness, will be optimised to ensure commercial viability.
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Books on the topic "Hybrid associate"

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Saul, R. A. Analysis of Hybrid III lower leg instrumentation and an associated injury citerion. National Highway Traffic Safety Administration, 1992.

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S, Yau Timothy, Zaininger H. W, Bernard M. J, et al., eds. Utility emissions associated with electric and hybrid vehicle (EHV) charging: Interim report. U.S. Dept. of Energy, Assistant Secretary for Energy Efficiency and Renewable Energy, Office of Transportation Technologies, Electric and Hybrid Propulsion Division, 1993.

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bonet, lisa. Microsoft Certified : Windows Server Hybrid Administrator Associate Practice Questions: Microsoft AZ-800 Exam. Independently Published, 2022.

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Jacobs, Jane. SAP Certified Application Associate - SAP Hybris Cloud for Service. Createspace Independent Publishing Platform, 2017.

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Fishpool, Megan. Hybrid Prints. Bloomsbury Publishing Plc, 2009. http://dx.doi.org/10.5040/9781789942545.

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This book reveals the secrets of hybrid and combination techniques. Combined techniques are often used by printmakers as tricky ways of achieving particular results, and then not fully acknowledged or detailed in the information that accompanies the print when it is exhibited. Combination printmaking has a long history, but the explosion of media now available to printmakers has opened up many new possibilities. Learning the techniques associated with creating hybrid prints is, at the moment, a case of trial-and-error for most printmakers, unless they are lucky enough to have a tame and generous printmaking friend who will share their secrets; most printmakers closely guard the secrets of how they make their unique prints. This book will explain a lot of these 'secret' methods and techniques.
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Staton, Cecil P. A Sturdy American Hybrid: Associated New American Colleges, Member Profiles and Distinctive Features. Mercer University Press, 2003.

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Peeran, Syed M. Combined Endovascular and Surgical Retrograde Superior Mesenteric Artery Recanalization. Edited by S. Lowell Kahn, Bulent Arslan, and Abdulrahman Masrani. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199986071.003.0027.

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Acute mesenteric ischemia is a life-threatening vascular emergency associated with a very high mortality rate. In the setting of necrotic bowel, the current standard of care requires a laparotomy with bowel resection and surgical or endovascular revascularization of the superior mesenteric artery. Unfortunately, mesenteric bypass confers high perioperative mortality, in some reports up to 45%. A hybrid technique that employs an exploratory laparotomy, catheterization of the distal superior mesenteric artery, and stent deployment across the atherosclerotic lesion was first described in 2004 for the treatment of acute-on-chronic mesenteric ischemia. This chapter describes the appropriate clinical indications, the technical aspects of performing this hybrid procedure, as well as the challenges and common pitfalls encountered.
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Narlikar, A. V., ed. The Oxford Handbook of Small Superconductors. Oxford University Press, 2017. http://dx.doi.org/10.1093/oxfordhb/9780198738169.001.0001.

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This handbook examines cutting-edge developments in research and applications of small or mesoscopic superconductors, offering a glimpse of what might emerge as a giga world of nano superconductors. Contributors, who are eminent frontrunners in the field, share their insights on the current status and great promise of small superconductors in the theoretical, experimental, and technological spheres. They discuss the novel and intriguing features and theoretical underpinnings of the phenomenon of mesoscopic superconductivity, the latest fabrication methods and characterization tools, and the opportunities and challenges associated with technological advances. The book is organized into three parts. Part I deals with developments in basic research of small superconductors, including local-scale spectroscopic studies of vortex organization in such materials, Andreev reflection and related studies in low-dimensional superconducting systems, and research on surface and interface superconductivity. Part II covers the materials aspects of small superconductors, including mesoscopic effects in superconductor–ferromagnet hybrids, micromagnetic measurements on electrochemically grown mesoscopic superconductors, and magnetic flux avalanches in superconducting films with mesoscopic artificial patterns. Part III reviews the current progress in the device technology of small superconductors, focusing on superconducting spintronics and devices, barriers in Josephson junctions, hybrid superconducting devices based on quantum wires, superconducting nanodevices, superconducting quantum bits of information, and the use of nanoSQUIDs in the investigation of small magnetic systems.
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Gheciu, Alexandra. Normative Dilemmas and Challenges of Security Commercialization. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198813064.003.0006.

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Chapter 6 places the analysis developed in this book in a broader normative perspective, focusing on a series of challenges and dilemmas associated with the transformation in the logic of security provision examined in the previous chapters. It pays particular attention to the ways in which the particular dynamics of commercialization of security provision have involved departures from principles of transparency and democratic accountability, and the problems associated with such departures in countries with long histories of anti-democratic governance. Finally, the chapter reflects on the difficulties of promoting liberal-democratic standards of “good governance” in contexts in which (in)security is performed by hybrid networks of security entrepreneurs that blur the boundaries between licit/illicit activities.
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Smith, Holly M. The Problems of Ignorance and Uncertainty. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780199560080.003.0009.

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Chapter 9 turns to further epistemic barriers for decision makers: the problems of (nonmoral) ignorance and (nonmoral) uncertainty. The concepts of “ignorance” and “uncertainty” are elucidated, the problem of uncertainty is defined, and it is argued that the problem of ignorance should be treated as a special case of the problem of uncertainty. The three salient attempts to solve the problem are the Pragmatic, Austere, and Hybrid approaches. Combined solutions to the problem of error and the problem of uncertainty are explored, and it is argued that the only feasible approaches marry the Austere Response to the problem of error with the Hybrid Response to the problem of uncertainty in a two-tier system. The top-tier code provides the correct theoretical account of right and wrong, while the lower-tier rules provide associated decision-guides. Consistency requires that different normative terms be used by the top-tier rules and by the lower-tier rules.
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Book chapters on the topic "Hybrid associate"

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Shakya, Praveen, and Umakanta Meher. "Flutter investigation of MW sized hybrid wind turbine blade." In Aerospace and Associated Technology. Routledge, 2022. http://dx.doi.org/10.1201/9781003324539-79.

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Zhang, Weipan, Weipeng Li, and Bin Ren China. "Modelling and design of hybrid reluctance actuator for fast steering mirror." In Aerospace and Associated Technology. Routledge, 2022. http://dx.doi.org/10.1201/9781003324539-81.

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Talreja, Neetu, Divya Chauhan, and Mohammad Ashfaq. "Carbon-Based Hybrid Materials for Remediation Technology." In Emerging Contaminants and Associated Treatment Technologies. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-22269-6_13.

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Liu, Wei, Haibo Wang, Weizong Wang, et al. "PIC/MCC simulation of axial ring-cusp hybrid discharge in the micro ion thruster ionisation chamber." In Aerospace and Associated Technology. Routledge, 2022. http://dx.doi.org/10.1201/9781003324539-89.

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Lee, Jung-Hun, and Suh-Hyun Cheon. "Associated Word Extraction System for Search Query Expansion Based on HITS." In Convergence and Hybrid Information Technology. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-24106-2_75.

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Slama, Dirk. "Hybrid Models." In The Digital Playbook. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-030-88221-1_10.

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AbstractHybrid models that combine aspects of the Digital OEM and the Digital Equipment Operator are more often the norm than the exception. Nevertheless, differentiating between these two roles can be very helpful for understanding many of the different concepts associated with them. This chapter looks at hybrid models in more detail, following again the why, what, how structure from the Introduction (Fig. 10.1).
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Del Moral-Argumedo, Marco Julio, Alberto Ochoa-Zezzatti, and Alberto Aguilar-Lasserre. "Intelligent Mobile Application to Determine the Existence of Medicines Associated with COVID-19 in a Social Network of Medical Dispensaries in a Smart City." In Hybrid Intelligent Systems. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-73050-5_9.

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Khosla, Rajiv, and Tharam Dillon. "Association Systems — Task Structure Level Associative Hybrid Architecture." In Engineering Intelligent Hybrid Multi-Agent Systems. Springer US, 1997. http://dx.doi.org/10.1007/978-1-4615-6223-8_6.

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Bucholtz, Ianis, and Laura Sūna. "‘I Am One of Them’: Exploring the Communication of Identity of Latvian Migrants on Social Networking Sites." In IMISCOE Research Series. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-12092-4_11.

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Abstract This chapter analyses how ethnic transnational identities are manifested and negotiated on the social networking sites used by Latvian migrants. Although migrants as well as other people use various personal media, including Skype, chat apps such as WhatsApp and telephones, social networking sites stand out with the diversity of functions in migrant communication. This includes one-to-one exchanges, group communication and the ability to locate and connect with users who may or may not be familiar offline. We argue that social networking sites and particularly thematic groups on these sites that migrants create and join serve as forums or bulletin boards where they exchange practical information and are able to communicate with other Latvians who live nearby – and that these uses have implications for the communication of identity. The empirical data in the chapter comes from 20 semi-structured interviews with Latvian migrants who live in a variety of countries and were recruited for the study on social networking sites, as well as survey data, all of which were collected within the research project The Emigrant Communities of Latvia: National Identity, Transnational Relations and Diaspora Politics. The results demonstrate that migrant interactions on social networking sites do not necessarily lead to the homogenisation of migrants’ conception of what ‘being a Latvian’ means. The increased ability to maintain associations with diverse online and offline social circles provides a migrant with a variety of identity elements to associate with. As a result, hybrid identities may emerge. A migrant can identify with the host society yet still reject some of its characteristics – and choose Latvian alternatives instead.
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Bruns, R., and C. J. Peterson. "Yield and stability factors associated with hybrid wheat." In Developments in Plant Breeding. Springer Netherlands, 1997. http://dx.doi.org/10.1007/978-94-011-4896-2_4.

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Conference papers on the topic "Hybrid associate"

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Zhao, Dong, and Deyi Xue. "A Hybrid Relationship Modeling Scheme for Parametric Design Considering Uncertainties." In ASME 2008 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2008. http://dx.doi.org/10.1115/detc2008-49702.

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This research introduces a new scheme to model different types of relationships in parametric design considering uncertainties. First a hybrid parameter relationship network is developed to associate the parameters through their relationships. In this hybrid parameter relationship network, in addition to the deterministic parameters and relationships, non-deterministic parameters (e.g., random parameters and fuzzy parameters) and non-deterministic relationships (e.g., neural network relationships and fuzzy relationships) can also be modeled. Propagation of parameter values and their uncertainties through this hybrid parameter relationship network is then investigated. Two optimization mechanisms, probability based design optimization and possibility based design optimization, are employed to identify the optimal design considering objective random uncertainties and subjective fuzzy uncertainties. A computer tool has been implemented and used for the optimal design of a solid oxide fuel cell (SOFC) system.
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Hendry, Morgan L., and Nicholas Bellamy. "Hidden Advantages and Strategic Leaps for CODAG, CODELAG, CODELOG and Hybrid Propulsion Systems." In ASME Turbo Expo 2020: Turbomachinery Technical Conference and Exposition. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/gt2020-15543.

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Abstract Navies worldwide are increasingly considering and adopting propulsion plants with electric propulsion for cruise and ship silent operation, and gas turbines for boost propulsion for high speed. These propulsion plants, often referred to as hybrid propulsion, utilize water jets, controllable pitch propellers, or fixed pitch propellers, and have design and overall configuration to fit into naval ships with various size hulls such as would be the case with corvettes, frigates, destroyers, cruisers, etc. Therefore, size, weight, and space of the propulsion plant is important, but equally important is limiting associated machinery which must be used with a particular hybrid propulsion plant design selected. In addition, propulsion design engineers, in conjunction with naval architects, shipyards and navies, must consider fuel efficiencies, machinery efficiencies, weight of all the associated machinery, placement in the hull, first time cost, and life cycle maintenance with associated cost when selecting the configuration of the propulsion system’s associated machinery. Manning levels are dictated by these parameters and in the end, it must be realized that the purpose of the ship mission can be compromised if reliability is not high and premature failures occur. This paper is a more in depth analysis of hybrid propulsion systems for naval ships of various sizes, and analysis of the associate machinery emphasizing ship weight and space savings, fuel savings, cost savings, mean time between failures and mean time to repair which results in lower manning requirements and increased mission readiness. By the time this paper is published, more than 250 SSS Clutches will be installed in US Navy Arleigh Burke Destroyers, 32 are operating in low speed propeller shafts of British Navy Type 23 ships, 2 in the Japanese Navy’s Asuka Class and 16 in low speed propeller shafts of Royal Korean Navy FFX Batch II frigates. At the time of abstract submission, all three programs referenced above have cumulatively had zero defects attributable to SSS Clutch material, function, design, or quality. While the US Navy are given occasional reminders of why alternative clutch designs remain ineffective, unreliable and remarkedly inefficient, other nations’ vertically tiered supply chains and inexperienced engineers are shielded from similar issues.
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S. Pires, Fabiano, Cícero A. L Pahins, and Paulo Fonseca. "Improving Workload Estimation in Inexperienced Teams with Hybrid Agile Approach." In 9th International Conference on Natural Language Processing (NLP 2020). AIRCC Publishing Corporation, 2020. http://dx.doi.org/10.5121/csit.2020.101426.

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SCRUM framework is an agile technique that is widely used by development teams in order deliver incremental value to customers and dynamically react to project needs. SCRUM framework might be adapted to conform the development team specificities. In the context of an industry project, we have found that an inexperienced development team frequently faced difficulties with estimating the time needed to complete tasks, which led to missed deadlines in most of the projects. Such problem hampers the risk management and degrades the relationship with the customer. Upon closer analysis, it was identified that the main reason to this issue was the team's inability to breaking down a larger task into smaller sub-tasks and associate a realistic workload to each part. Then, based on traditional techniques, a structured approach to workload estimation was introduced in the SCRUM planning meeting to leverage the team's estimation skill. This approach was implemented in two development projects and increased the accuracy in the estimate defined by the team, yielding realistic schedules and increasing technical visibility.
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To, C. W. S. "Large Nonlinear Random Responses of Spatially Non-Homogeneous Stochastic Shell Structures." In ASME 2006 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2006. http://dx.doi.org/10.1115/detc2006-99261.

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This paper is concerned with large nonlinear random response analysis of spatially non-homogeneous stochastic shell structures under transient excitations. The latter are treated as nonstationary random excitation processes. The emphases are on (i) spatially non-homogeneous and homogeneous stochastic shell structures with large spatial variations, (ii) large nonlinear responses with finite strains and finite rotations, and (iii) intensive nonstationary random disturbances. The shell structures are approximated by the lower order mixed or hybrid strain based triangular shell finite elements developed earlier by the author and his associate. The nonstationary random nonlinear responses are evaluated by a procedure that consists of the stochastic central difference method, time co-ordinate transformation, and modified adaptive time scheme. Computationally, the procedure is very efficient compared with those entirely and partially based on Monte Carlo simulation, and is free from the limitations associated with those employing perturbation approximation techniques, such as the so-called stochastic finite element or probabilistic finite element method.
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van den Heuvel, Robert. "COMMANDS trial: A paradigm shift in LR-MDS-associated anaemia." In EHA2023 Hybrid Congress, edited by Gert Ossenkoppele. Medicom Medical Publishers, 2023. http://dx.doi.org/10.55788/24d4d50c.

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Pratt, S. D., M. Sivakumar, and S. Manoochehri. "A Knowledge-Based Engineering System for the Design of Injection Molded Plastic Parts." In ASME 1993 Design Technical Conferences. American Society of Mechanical Engineers, 1993. http://dx.doi.org/10.1115/detc1993-0316.

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Abstract This study presents a knowledge-based engineering system for the design of injection molded plastic parts which is built around a commercial object-oriented design language. Knowledge-based engineering is an implementation paradigm in which the knowledge about the part is stored along with its geometry and the knowledge is used to verify the manufacturability and processability of the part. This system enables the designer to represent the plastic part in terms of hybrid features which associate product and process knowledge with part geometry. Engineering rules about part moldability and strength, process and material considerations, and mold design are captured in the system. To illustrate the capability and application of the system to real-world problems, the design of an enclosure for a portable data entry device is pursued. This exercise demonstrates the effectiveness and robustness of the system which applied appropriate rules at different stages of design to make the part inherently moldable.
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Kim, Eun-Soo, Sang-Yi Yi, and Sang-Ro Yoon. "Multi-target tracking system based on a joint transform correlator and a neural network algorithm." In OSA Annual Meeting. Optica Publishing Group, 1992. http://dx.doi.org/10.1364/oam.1992.thaa6.

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Multi-target tracking systems have been under intensive study and in use for many years for a number of applications. More recently, emphasis has been placed on the application of real-time multi-target tracking procedures to situations involving large number of targets. In this paper, we describe a hybrid optoneural system to tackle real-time multi-target tracking. In our system, an optical joint transform correlator is used for real-time adaptive target tracking. But, because of many correlation signals in multi-target tracking problem, a data association algorithm can be used to associate each of the peak's correlation signals to the correct trajectories of the target's motion. Since the computational load on the conventional tracking algorithms increases rapidly with the number of targets tracked, in this paper, a new simple Hebbian learning algorithm is introduced to obtain the respective moving probabilities of the multi-target in real-time, and the data association is achieved in Hopfield optimization neural networks.
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Robinson, M. G., K. M. Johnson, D. Jared, D. Doroski, S. Wichart, and G. Moddel. "Custom designed electro-optic components for optically implemented, multi-layer neural networks." In Optical Computing. Optica Publishing Group, 1991. http://dx.doi.org/10.1364/optcomp.1991.me7.

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Optical implementations of one-layer, perceptron-like neural networks have been shown to be very successful at associating pattern/target sets despite large system errors [1,2]. It has also been shown that large systems can be realized with such architectures (≥4 x 104 interconnections [2,3]), and appreciable processing speeds have been demonstrated (&gt;108 interconnections/sec [4]). However, single layer networks are limited due to their inability to associate patterns that are not linearly separable. A more general network is the two layer network, which is able to model arbitrary functions, and create any decision boundary within the input vector pattern space [5]. In order to implement such a network, it is necessary to perform a nonlinearity at the hidden layer before performing a subsequent matrix multiplication. In general, optical materials performing fast nonlinear processing require high optical powers. Hybrid opto-electronic devices can perform nonlinear operations at moderate speeds and low optical powers [6].
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García-Duarte, H. A., M. C. Ruiz-Cañas, and R. A. Perez-Romero. "Combining Nanocatalyts with Solvent as a Strategy to Improve Steam-Based Hybrid Technology: Phase Behaviour Modelling and Thermal Simulation Approach." In SPE Improved Oil Recovery Conference. SPE, 2024. http://dx.doi.org/10.2118/218136-ms.

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Abstract As a strategy to optimize the recovery and energy efficiency in cyclic steam stimulation (CSS) processes, the alternative of combining steam - nanosolvents has been under study in Colombian heavy oil reservoirs. The use of oil-based nanocatalysts (nanosolvents) in combination with steam allows extending the effectiveness of the catalyst, transporting it better within the reservoir due to the solubility of naphtha in the crude oil. The interaction phenomena associate with this hybrid technology must be evaluated under a robust phase behavior study which represent oil - solvent interaction analysis and, the effect on the oil density and oil viscosity at different temperatures. This work shows a methodology to incorporate solvent/oil mixtures phase behavior into the field numerical model. Based on experimental PVT tests (such as compositional analysis and fluids characterization) a fluid model was developed. Using Peng Robinson Modified Equation experimental data were adjusted such as GOR and density. Additionally, the mixture viscosity were fitted with the modified Pedersen equation. Incorporate the effect of nanocatalysts in the numerical modeling required the grouping by pseudo-components of live oil according to the proposed kinetic model, obtaining a good adjustment and a better representation of the live oil. This allowed the inclusion of the component's properties such as asphaltenes and upgrading oil used in the kinetic model of the CSS + solvent enhanced with nanoparticles technology. The experimental results indicate the high solubility of the solvent in crude oil, due that a linear mixture rules for naphtha - oil was developed. Additionally, a representative fluid model is mandatory to represent aquathermolysis catalytic reaction in the CSS. The modelling results show that the highest incremental recovery of the nanofluid was achieved in early stages of CSS with an increase of 23% concerning the baseline. Likewise, a sensitivity analysis was developed based on a fixed cumulative oil production in the presence of nanofluids, obtaining a 61% reduction in the steam injection rate, indicating that the hybrid technology not only generates positive impacts on recovery but also positively impacts on improving energy efficiency and reducing the carbon footprint. A novel methodology to represent the fluid interaction in presence of nanocatalysts in the numerical modeling was developed as a strategy to incorporate oil compositional changes in thermal hybrid process.
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Gizatullina, Gulgina Alimzhanovna, Elmira Kuandykova, Dinara Omirzakova, and Gulvira Imanbayeva. "LESSONS FROM THE PANDEMIC: THE EXPERIENCE OF THE REPUBLIC OF KAZAKHSTAN." In Themed collection of papers from Foreign International Scientific Conference «Trends in the development of science and Global challenges». Crossref, 2022. http://dx.doi.org/10.37539/man4.2022.86.53.006.

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The article by Associate Professor Gizatullina G.A. analyzes the events occurring in the Republic of Kazakhstan during the pandemic. The author identifies four lessons that humanity must learn from the current reality. The first lesson is that the role of the state in the modern world must increase. The second lesson is the need for re-industrialization, in any case, Kazakhstan needs industrial development. The third lesson - it is necessary to restore medicine, especially such specialties as pulmonologists, virologists, microbiologists. As President Tokayev wrote about it correctly: “In the era of hybrid wars we need a developed medicine. The fourth lesson is that the effectiveness of a state is determined not by the number of officials, but by their quality. The pandemic has shown that the developed bureaucratic system is very burdensome, in connection with which Tokayev suggested reducing the bureaucratic apparatus and introducing young personnel there. The author offers not just an analysis of the events that took place, but also constructs a prospect of social development based on a knowledge-based economy.
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Reports on the topic "Hybrid associate"

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Westwood, James H., Yaakov Tadmor, and Hanan Eizenberg. Identifying the genes involved in host root perception by root parasitic weeds: Genetic and transcriptomic analysis of Orobanche hybrids differing in signal response specificity. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7598145.bard.

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Seeds of the root parasitic plants of the genus Orobanchegerminate specifically in response to host-derived germination signals, which enables parasites to detect and attack preferred hosts. The best characterized class of germination stimulants is the strigolactones (SL), although some species respond to sesquiterpene lactones such as dehydrocostuslactone (DCL). Despite great progress in characterizing the SL signaling system in plants, the mechanism(s) by which parasite species detect specific compounds remains poorly understood. The goal of our project was to identify and characterize the genes responsible for stimulant specificity in O. cernuaand O. cumana. These two species are closely related, but differ in host range, with O. cernuaparasitizingSolanaceous crops such as tomato (and responding to SLs), and O. cumanaspecifically parasitizing sunflower (and responding to DCL). We used a genetic approach based on O. cernuax O. cumanahybrids to associate germination response with genes. We found that these parasite species each have multiple copies of KAI2d genes, which function in SL perception. In O. cernua, the OrceKAI2d2 responds to SL stimulants and is most consistently associated with hybrid lines that respond to SLs. For O. cumana, an apparently linked block of KAI2d genes was associated with response to DCL in hybrid lines, but we found no strong evidence that any of the OrcuKAI2d genes specifically recognize the DCL stimulant. Remarkably, one O. cumanagene, OrcuKAI2d5, responds to certain SLs in a genetic complementation assay, even though hybrid lines containing this gene show fidelity to DCL. In summary, we have identified the SL receptor in O. cernua, but the DCL receptor in O. cumanaremains unknown. Our data point to involvement of additional genes and yet greater levels of complexity regulating germination specificity in Orobanche. BARD Report - Project 4616 Page 2 of 8
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Avni, Adi, and Gitta L. Coaker. Proteomic investigation of a tomato receptor like protein recognizing fungal pathogens. United States Department of Agriculture, 2015. http://dx.doi.org/10.32747/2015.7600030.bard.

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Maximizing food production with minimal negative effects on the environment remains a long-term challenge for sustainable food production. Microbial pathogens cause devastating diseases, minimizing crop losses by controlling plant diseases can contribute significantly to this goal. All plants possess an innate immune system that is activated after recognition of microbial-derived molecules. The fungal protein Eix induces defense responses in tomato and tobacco. Plants recognize Eix through a leucine-rich-repeat receptor- like-protein (LRR-RLP) termed LeEix. Despite the knowledge obtained from studies on tomato, relatively little is known about signaling initiated by RLP-type immune receptors. The focus of this grant proposal is to generate a foundational understanding of how the tomato xylanase receptor LeEix2 signals to confer defense responses. LeEix2 recognition results in pattern triggered immunity (PTI). The grant has two main aims: (1) Isolate the LeEix2 protein complex in an active and resting state; (2) Examine the biological function of the identified proteins in relation to LeEix2 signaling upon perception of the xylanase elicitor Eix. We used two separate approaches to isolate receptor interacting proteins. Transgenic tomato plants expressing LeEix2 fused to the GFP tag were used to identify complex components at a resting and activated state. LeEix2 complexes were purified by mass spectrometry and associated proteins identified by mass spectrometry. We identified novel proteins that interact with LeEix receptor by proteomics analysis. We identified two dynamin related proteins (DRPs), a coiled coil – nucleotide binding site leucine rich repeat (SlNRC4a) protein. In the second approach we used the split ubiquitin yeast two hybrid (Y2H) screen system to identified receptor-like protein kinase At5g24010-like (SlRLK-like) (Solyc01g094920.2.1) as an interactor of LeEIX2. We examined the role of SlNRC4a in plant immunity. Co-immunoprecipitation demonstrates that SlNRC4a is able to associate with different PRRs. Physiological assays with specific elicitors revealed that SlNRC4a generally alters PRR-mediated responses. SlNRC4a overexpression enhances defense responses while silencing SlNRC4 reduces plant immunity. We propose that SlNRC4a acts as a non-canonical positive regulator of immunity mediated by diverse PRRs. Thus, SlNRC4a could link both intracellular and extracellular immune perception. SlDRP2A localizes at the plasma membrane. Overexpression of SlDRP2A increases the sub-population of LeEIX2 inVHAa1 endosomes, and enhances LeEIX2- and FLS2-mediated defense. The effect of SlDRP2A on induction of plant immunity highlights the importance of endomembrane components and endocytosis in signal propagation during plant immune . The interaction of LeEIX2 with SlRLK-like was verified using co- immunoprecipitation and a bimolecular fluorescence complementation assay. The defence responses induced by EIX were markedly reduced when SlRLK-like was over-expressed, and mutation of slrlk-likeusing CRISPR/Cas9 increased EIX- induced ethylene production and SlACSgene expression in tomato. Co-expression of SlRLK-like with different RLPs and RLKs led to their degradation, apparently through an endoplasmic reticulum-associated degradation process. We provided new knowledge and expertise relevant to expression of specific be exploited to enhance immunity in crops enabling the development of novel environmentally friendly disease control strategies.
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Goel, Dr Divanshu, and Dr Manjeet Singh. HYBRID EXTERNAL FIXATION FOR PROXIMAL TIBIAL FRACTURES. World Wide Journals, 2023. http://dx.doi.org/10.36106/ijar/1505336.

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Introduction: Intraarticular fractures of the tibial plateau and periarticular fractures of the proximal tibia, caused by high energy trauma pose a therapeutic dilemma. Such fractures are associated with extensive soft tissue damage with or without compound injury. The management of such high velocity injuries become a challenge to the trauma surgeons. The goals of these periarticular fractures management are 1. Restoration of joint congruity by anatomic reduction 2. Stable xation of fractures thus allowing early movements 3. Proper care of injured soft tissues. In earlier days uniplanar external xation were used with various complications like pin track infections and decreased stability. In this study we present the use of hybrid external xation system which includes Ilizarov ring xator and AO rod external xator connected with indigenously manufactured connecting clamps and short shafts augmented with or without minimal internal xation. The purpose of this study is to assess the utility of this hybrid external xation system and to analyse the functional outcome, soft tissue healing and fracture union. To assess the performance of the Hybrid External Fixator Aim and Objective: in the treatment of different types of proximal tibial fractures, to evaluate the functional outcome, soft tissue healing and fracture union and radiological outcome, to evaluate the biomechanical and biological advantage of hybrid external xator, to assess the utility of the indigenously made connecting clamps. Material and Method: The study included 21 cases of periarticular fractures of the proximal tibia which were treated by use of 5/8th Ilizarov ring, AO tubular external xator and with indigenously manufactured connecting clamps &amp; short shaft in a hybrid mode. All cases were prospectively followed up and studied. Almost all the cases (99%) had sustained Road trafc Accidents (high velocity injuries) except one case which had sustained injury by fall of cement wall over her leg. Minimum follow up – 1.5 months, maximum follow up – 12 months, mean follow up – 6.42 months. All fractures were followed according to a protocol. All fractures were treated with either CLOSED REDUCTION AND HYBRID EXTERNAL FIXATION OR WITH MINIMAL OPEN REDUCTION AND A HYBRID SYSTEM. The study group was consisted of 16 males (76%) and 5 females (24%) with an average age for males of 43.06 years (range 25 to 65) and for females of 53.4 years (range 41 to 59). All the patients were in the age group of 26 to 65 years, mean age is 43.09. In the present s Result: tudy of 21 cases, the use of Hybrid external xation, as a denite treatment, for high – energy proximal tibia bicondylar fractures proved to be benecial.
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Parks, K., P. Denholm, and T. Markel. Costs and Emissions Associated with Plug-In Hybrid Electric Vehicle Charging in the Xcel Energy Colorado Service Territory. Office of Scientific and Technical Information (OSTI), 2007. http://dx.doi.org/10.2172/903293.

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5

Blum, Abraham, Henry T. Nguyen, and N. Y. Klueva. The Genetics of Heat Shock Proteins in Wheat in Relation to Heat Tolerance and Yield. United States Department of Agriculture, 1993. http://dx.doi.org/10.32747/1993.7568105.bard.

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Fifty six diverse spring wheat cultivars were evaluated for genetic variation and heritability for thermotolerance in terms of cell-membrane stability (CMS) and triphenyl tetrazolium chloride (TTC) reduction. The most divergent cultivars for thermotolerance (Danbata-tolerant and Nacozari-susceptible) were crossed to develop an F8 random onbred line (RIL) population. This population was evaluated for co-segragation in CMS, yield under heat stress and HSP accumulation. Further studies of thermotolerance in relations to HSP and the expression of heterosis for growth under heat stress were performed with F1 hybrids of wheat and their parental cultivars. CMS in 95 RILs ranged from 76.5% to 22.4% with 71.5% and 31.3% in Danbata and Nacozari, respectively. The population segregated with a normal distribution across the full range of the parental values. Yield and biomass under non-stress conditions during the normal winter season at Bet Dagan dit not differ between the two parental cultivar, but the range of segregation for these traits in 138 RILs was very high and distinctly transgressive with a CV of 35.3% and 42.4% among lines for biomass and yield, respectively. Mean biomass and yield of the population was reduced about twofold when grown under the hot summer conditions (irrigated) at Bet Dagan. Segregation for biomass and yield was decreased relative to the normal winter conditions with CV of 20.2% and 23.3% among lines for biomass and yield, respectively. However, contrary to non-stress conditions, the parental cultivars differed about twofold in biomass and yield under heat stress and the population segregated with normal distribution across the full range of this difference. CMS was highly and positively correlated across 79 RILs with biomass (r=0.62**) and yield (r=0.58**) under heat stress. No such correlation was obtained under the normal winter conditions. All RILs expressed a set of HSPs under heat shock (37oC for 2 h). No variation was detected among RILs in high molecular weight HSP isoforms and they were similar to the patterns of the parental cultivars. There was a surprisingly low variability in low molecular weight HSP isoforms. Only one low molecular weight and Nacozari-specific HSP isoform (belonging to HSP 16.9 family) appeared to segregate among all RILs, but it was not quantitatively correlated with any parameter of plant production under heat stress or with CMS in this population. It is concluded that this Danbata/Nacozari F8 RIL population co-segregated well for thermotolerance and yield under heat stress and that CMS could predict the relative productivity of lines under chronic heat stress. Regretfully this population did not express meaningful variability for HSP accumulation under heat shock and therefore no role could be seen for HSP in the heat tolerance of this population. In the study of seven F1 hybrids and their parent cultivars it was found that heterosis (superiority of the F1 over the best parent) for CMs was generally lower than that for growth under heat stress. Hybrids varied in the rate of heterosis for growth at normal (15o/25o) and at high (25o/35o) temperatures. In certain hybrids heterosis for growth significantly increased at high temperature as compared with normal temperature, suggesting temperature-dependent heterosis. Generally, under normal temperature, only limited qualitative variation was detected in the patterns of protein synthesis in four wheat hybrids and their parents. However, a singular protein (C47/5.88) was specifically expressed only in the most heterotic hybrid at normal temperature but not in its parent cultivars. Parental cultivars were significantly different in the sets of synthesized HSP at 37o. No qualitative changes in the patterns of protein expression under heat stress were correlated with heterosis. However, a quantitative increase in certain low molecular weight HSP (mainly H14/5.5 and H14.5.6, belonging to the HSP16.9 family) was positively associated with greater heterosis for growth at high temperature. None of these proteins were correlated with CMS across hybrids. These results support the concept of temperature-dependent heterosis for growth and a possible role for HSP 16.9 family in this respect. Finally, when all experiments are viewed together, it is encouraging to find that genetic variation in wheat yield under chronic heat stress is associated with and well predicted by CMS as an assay of thermotolerance. On the other hand the results for HSP are elusive. While very low genetic variation was expressed for HSP in the RIL population, a unique low molecular weight HSP (of the HSP 16.9 family) could be associated with temperature dependant heterosis for growth.
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Fast, L. D., C. R. Valeri, and J. P. Crowley. Immune Responses to MHC Homozygous Lymphoid Cells in Murine F1 Hybrid Recipients: Implications for Transfusion Associated Graft-Versus Host Disease. Defense Technical Information Center, 1994. http://dx.doi.org/10.21236/ada360361.

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Roy, Dibyendu, C. J. Bolech, and Nayana Shah. Nature of the zero-bias conductance peak associated with Majorana bound states in topological phases of semiconductor-superconductor hybrid structures. Office of Scientific and Technical Information (OSTI), 2013. http://dx.doi.org/10.2172/1073055.

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8

Pasupuleti, Murali Krishna. Quantum Semiconductors for Scalable and Fault-Tolerant Computing. National Education Services, 2025. https://doi.org/10.62311/nesx/rr825.

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Abstract: Quantum semiconductors are revolutionizing computing by enabling scalable, fault-tolerant quantum processors that overcome the limitations of classical computing. As quantum technologies advance, superconducting qubits, silicon spin qubits, topological qubits, and hybrid quantum-classical architectures are emerging as key solutions for achieving high-fidelity quantum operations and long-term coherence. This research explores the materials, device engineering, and fabrication challenges associated with quantum semiconductors, focusing on quantum error correction, cryogenic control systems, and scalable quantum interconnects. The study also examines the economic feasibility, industry adoption trends, and policy implications of quantum semiconductors, assessing their potential impact on AI acceleration, quantum cryptography, and large-scale simulations. Through a comprehensive analysis of quantum computing frameworks, market trends, and emerging applications, this report provides a roadmap for integrating quantum semiconductors into next-generation high-performance computing infrastructures. Keywords: Quantum semiconductors, scalable quantum computing, fault-tolerant quantum processors, superconducting qubits, silicon spin qubits, topological qubits, hybrid quantum-classical computing, quantum error correction, quantum coherence, cryogenic quantum systems, quantum interconnects, quantum cryptography, AI acceleration, quantum neural networks, post-quantum security, quantum-enabled simulations, quantum market trends, quantum computing policy, quantum fabrication techniques.
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Juvik, John A., Avri Bar Zur, and Torbert R. Rocheford. Breeding for Quality in Vegetable Maize Using Linked Molecular Markers. United States Department of Agriculture, 1993. http://dx.doi.org/10.32747/1993.7568764.bard.

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Recently, the vegetable corn industry has shifted from the use of traditional cultivars with the sugary1 (su1) endosperm mutation to newer hybrids homozygous for the shrunken2 (sh2) or sugary enhancer1 (se1) genes. With greater kernel sucrose content, these hybrids are preferred by consumers and retain sugar for longer post harvest periods, providing the industry with more time to marker products with superior quality. Commercialization has been hindered, however, by reduced field emergence, and the establishment of stands with heterogeneous uniformity and maturities. This investigation was conducted to identify key biochemical and physiological characteristics in sh2 and se1 maize kernels associated with improved emergence, and stand establishment; and in immature ears at fresh harvest maturity, properties associated with eating quality. The location of genes or QTL controlling these kernel characteristics and other traits were then mapped to specific chromosomal regions by their linkage to molecular markers using two segregating F2:3 populations. This database was used to compare the efficiency of marker-assisted selection of key alleles with phenotypic selection for trait improvement. A model designed to uncover and quantify digenic interaction was applied to the datasets to evaluate the role of epistasis in the inheritance of quantitative traits.
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Veilleux, Richard E., Jossi Hillel, A. Raymond Miller, and David Levy. Molecular Analysis by SSR of Genes Associated with Alkaloid Synthesis in a Segregating Monoploid Potato Family. United States Department of Agriculture, 1994. http://dx.doi.org/10.32747/1994.7570550.bard.

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More than 15,000 anthers of an interspecific hybrid (CP2) between two diploid (2n=2x=24) potato species, Solanum chacoense (weedy) and S. phureja (cultivated), were cultured to generate a family of monoploid (haploid, 2n-1x=12) plants. Of 260 regenerated plants, 34 were monoploid, 210 diploid and 16 tetraploid. SSR analysis revealed that six monoploids were genetically identical and 14 diploids were homozygous, thus limiting the population to 42 (28 monoploids and 14 homozygous diploids). New microsatellite loci were developed for potato from database sequences (15), a conventional genomic library (6), an enriched library (18) and tomato (11). Of these, 13 were polymorphic in the CP2 family and 11 were used to study genetic segregatin. Four of 11 exhibited skewed segregation in the monoploid family. Seven of 18 microsatellite markers were polymorphic and informative on a set of 12 tetraploid potato cultivars. Acetylleptinidine (ALD) is the aglycone of leptines, a natural defense against insects, especially the highly destructuve Colorado potato beetle. ALD is absend in S. phureja but highly expressed in the S. chacoense parent of CP2. A backcross population between CP2 and tis S. phureja parent was used to examine segregation for ALD. Bulks of 10 backcross individuals that expressed ALD and 10 that did not were used to identify putative RAPD markers associatd with the trait. Of 80 primers tested, one putative marker amplified by OPQ02 was present in eight of ten individuals comprising the high bulk and absent in all 10 individuals comprising the low bulk. This is a putative marker for ALD expression in potato.
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