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Relevant bibliographies by topics / Hydantoin Analogues

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Academic literature on the topic 'Hydantoin Analogues'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "Hydantoin Analogues"

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Stanić, Petar, Marija Živković, and Biljana Šmit. "Synthesis and Characterization of Various Amino Acid Derived Thiohydantoins." Proceedings 9, no. 1 (2018): 37. http://dx.doi.org/10.3390/ecsoc-22-05690.

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Hydantoins and their sulfur containing analogues, thiohydantoins, are cyclic ureides that have attracted huge attention ever since their discovery. Most of them are biologically active compounds and several points of structural diversity have made them very synthetically attractive. Although substituents can be introduced to the hydantoin nucleus, most substituted hydantoins are synthesized from substrates already containing these groups, while forming the hydantoin nucleus. This is a common route to the synthesis of hydantoins and one of them is employed in this study. A series of 3-allyl-2-t

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EL-BARBARY, A. A., A. I. KHODAIR, and E. B. PEDERSEN. "ChemInform Abstract: Hydantoin Analogues of Thymidine." ChemInform 25, no. 11 (2010): no. http://dx.doi.org/10.1002/chin.199411269.

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Tian, XiaoXue, XingRong Peng, MuYuan Yu, et al. "Hydantoin and thioamide analogues from Lepidium meyenii." Phytochemistry Letters 25 (June 2018): 70–73. http://dx.doi.org/10.1016/j.phytol.2018.03.011.

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4

Allan, RD, C. Apostopoulos, and TW Hambley. "The Synthesis and Structure of a Cyclobutane Analog of Glutamic Acid With an Acetic Acid Side Chain." Australian Journal of Chemistry 48, no. 5 (1995): 919. http://dx.doi.org/10.1071/ch9950919.

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A synthetic route involving a hydantoin derivative of bicyclo [3.2.0]hept-2-ene has been investigated for the preparation of neurotransmitter analogues containing an additional acetic acid substituent on the cyclobutane ring of the potent NMDA receptor agonist trans-1-aminocyclobutane-1,3-dicarboxylic acid. X-Ray analysis showed that the major cyclobutane amino acid produced had the 2-acetic acid and 3-carboxylic acid substituents in the trans orientation as a result of epimerization during hydantoin hydrolysis.

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Todorov, Petar, Petia Peneva, Stela Georgieva, Jana Tchekalarova, Miroslav Rangelov, and Nadezhda Todorova. "Synthesis and characterization of new 5,5′-dimethyl- and 5,5′-diphenylhydantoin-conjugated hemorphin derivatives designed as potential anticonvulsant agents." New Journal of Chemistry 46, no. 5 (2022): 2198–217. http://dx.doi.org/10.1039/d1nj05235g.

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Herein, the synthesis and characterization of some novel N-modified hybrid analogues of hemorphins containing a C-5 substituted hydantoin residue as potential anticonvulsants and for the blockade of sodium channels are presented.

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Abadi, Ashraf H., Jochen Lehmann, Gary A. Piazza, Mohammad Abdel-Halim та Mohamed S. M. Ali. "Synthesis, Molecular Modeling, and Biological Evaluation of Novel Tetrahydro-β-Carboline Hydantoin and Tetrahydro-β-Carboline Thiohydantoin Derivatives as Phosphodiesterase 5 Inhibitors". International Journal of Medicinal Chemistry 2011 (23 лютого 2011): 1–9. http://dx.doi.org/10.1155/2011/562421.

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Two series of fused tetrahydro-β-carboline hydantoin and tetrahydro-β-carboline thiohydantoin derivatives with a pendant 2,4-dimethoxyphenyl at position 5 were synthesized, and chiral carbons at positions 5 and 11a swing from R,R to R,S, S,R, and S,S. The prepared analogues were evaluated for their capacity to inhibit phosphodiesterase 5 (PDE5) isozyme. The R absolute configuration of C-5 in the β-carboline hydantoin derivatives was found to be essential for the PDE5 inhibition. Chiral carbon derived from amino acid even if of the S configuration (L-tryptophan) may lead to equiactive or more a

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Marinov, Marin. "SYNTHESIS OF AMINO DERIVATIVES OF MONOTHIO- AND DITHIO- ANALOGUES OF CYCLOHEXANESPIRO-5-HYDANTOIN." Journal scientific and applied research 2, no. 1 (2012): 66–73. http://dx.doi.org/10.46687/jsar.v2i1.45.

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This article presents methods for synthesis of 3-amino derivatives of cyclohexanespiro-5-(2-thiohydantoin) and cyclohexanespiro-5-(2,4-dithiohydantoin). It was found out that the treatment of cyclohexanespiro-5-(2-thiohydantoin) with hydrazine hydrate under different reaction conditions led to obtaining of 3-amino derivative and 2-hydrazone of the initial compound. As a result of thionation of 3-aminocyclohexanespiro-5-hydantoin with P4S10 or Lawesson’s reagent, the corresponding dithio-analogue was synthesized. The structures of the products obtained were verified by IR, 1H NMR, 13C NMR and m

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El-Barbary, Ahmed A., Ahmed I. Khodair, and Erik B. Pedersen. "Synthesis and Antiviral Evaluation of Hydantoin Analogues of AZT." Archiv der Pharmazie 327, no. 10 (1994): 653–55. http://dx.doi.org/10.1002/ardp.19943271010.

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9

Georgieva, Stela, Petar Todorov, Jana Tchekalarova, et al. "Chemical Behavior and Bioactive Properties of Spinorphin Conjugated to 5,5′-Dimethyl- and 5,5′-Diphenylhydantoin Analogs." Pharmaceuticals 17, no. 6 (2024): 770. http://dx.doi.org/10.3390/ph17060770.

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The discovery of new peptides and their derivatives is an outcome of ongoing efforts to identify a peptide with significant biological activity for effective usage as a possible therapeutic agent. Spinorphin peptides have been documented to exhibit numerous applications and features. In this study, biologically active peptide derivatives based on novel peptide analogues of spinorphin conjugated with 5,5′-dimethyl (Dm) and 5,5′-diphenyl (Ph) hydantoin derivatives have been successfully synthesized and characterized. Scanning electron microscopy (SEM) and spectral methods such as UV-Vis, FT-IR (

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10

Kochetkov, Konstantin A., Olga N. Gorunova, and Natalia A. Bystrova. "Biologically Oriented Hybrids of Indole and Hydantoin Derivatives." Molecules 28, no. 2 (2023): 602. http://dx.doi.org/10.3390/molecules28020602.

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Indoles and hydantoins are important heterocycles scaffolds which present in numerous bioactive compounds which possess various biological activities. Moreover, they are essential building blocks in organic synthesis, particularly for the preparation of important hybrid molecules. The series of hybrid compounds containing indoles and imidazolidin-2-one moiety with direct C–C bond were synthesized using an amidoalkylation one-pot reaction. All compounds were investigated as a growth regulator for germination, growth and development of wheat seeds (Triticum aestivum L). Their effect on drought r

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Dissertations / Theses on the topic "Hydantoin Analogues"

1

Davis, Gary Cornelius. "Investigation of the local anesthetic binding site in voltage-gated sodium channels using cholic acid-,[a]-hydroxyamide-, and hydantoin-based analogs /." 2008. http://wwwlib.umi.com/dissertations/fullcit/3312129.

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Conference papers on the topic "Hydantoin Analogues"

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Kuran, Juan A. Caturelli, and Albertina G. Moglioni. "REACTIVITY STUDY OF METHYLCYCLOBUTYLKETONES AND CYCLOBUTANONES IN THE OBTENTION OF ANALOGS OF HYDANTOINIC NUCLEOSIDES." In 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_201391092028.

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