Log in

Relevant bibliographies by topics / Hydrazidy / Journal articles

To see the other types of publications on this topic, follow the link: Hydrazidy.

Journal articles on the topic 'Hydrazidy'

Author: Grafiati

Published: 4 June 2021

Last updated: 14 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Hydrazidy.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Ibrahim, Hassan K., Sayed H. El-Tamany, Reda F. El-Shaarawy, and Ibrahim M. El-Deen. "Synthesis and investigation of mass spectra of some novel benzimidazole derivatives." Macedonian Journal of Chemistry and Chemical Engineering 27, no. 1 (2008): 65. http://dx.doi.org/10.20450/mjcce.2008.248.

Full text

Abstract:

2-Substituted benzimidazoles (3) and (4a-c) were prepared via condensation of ethyl 2-thionyl-pyruvate (1) and hydrazidoyl derivatives (2a-c) with o-phenylene diamine in acetic acid. Acetylation of compound (4a) with acetic anhydride yielded the corresponding N-acetyl derivative (5). Treatment of compound 4b with hydrazine hydrate gave the corresponding hydrazino derivative (6). Reaction of 2-[(2-thionyl)acetyl)] benzimidazole (3) with hydrazine hydrate gave the pyrazolyl derivative (7) and hydrazino derivative (8). Alkylation of compound 3 with alkyl halide gave the corresponding 2,3-disubsti

APA, Harvard, Vancouver, ISO, and other styles

2

Elshaarawy, Reda F. M., and Christoph Janiak. "2-Thiophenecarbohydrazides: A Novel Efficient Method for the Synthesis of 2-Thiophenecarbohydrazide." Zeitschrift für Naturforschung B 66, no. 12 (2011): 1202–8. http://dx.doi.org/10.1515/znb-2011-1202.

Full text

Abstract:

Hydrazinolysis of carboxylic acid esters in alcoholic solutions is the standard method for preparing carbohydrazides (carboxylic hydrazides). Here we report an efficient process, involving the reaction of activated esters or amides with hydrazine, for the preparation of thiophenecarbohydrazides in yields larger than 90% and high purity. With this new method, a series of heteroaryl-, aryl-, or aralkyl- substituted carbohydrazides were synthesized and characterized. The X-ray crystal structure of 2-thiophenecarbohydrazide (thiophene-2-carboxylic hydrazide, 2-thenoyl-hydrazine) has revealed that

APA, Harvard, Vancouver, ISO, and other styles

3

Ananthi, Vadamalai, Kaliyaraj Rajalakshmi, Inbasekaran Muthuvel, and Ganesamoorthy Thirunarayanan. "Solid acidic FeCl3/Bentonite catalyzed solvent-free condensation: Synthesis, spectral studies and antimicrobial activities of some aryl hydrazine Schiff’s bases." Annales Universitatis Mariae Curie-Sklodowska, sectio AA – Chemia 71, no. 2 (2017): 127. http://dx.doi.org/10.17951/aa.2016.71.2.127.

Full text

Abstract:

<p>Some aryl hydrazide derivatives have been synthesized including 1-(3-chloro-4-nitrophenyl)-2-(3-substituted benzylidene) hydrazines by FeCl<sub>3</sub>/Bentonite catalyzed solvent-free condensation of substituted phenyl hydrazine and aldehydes under microwave irradiation. The yields of the hydrazides are more than 70%. The synthesized hydrazides are characterized by the physical constants, micro analysis and spectroscopic data. Effect of catalyst, solvent effect substituent effect and optimization of the catalyst was studied by the percentage of isolated yields. From the c

APA, Harvard, Vancouver, ISO, and other styles

4

Peng, Seng, Xiao Bin Tang, Hao Wang, Yan Wei, and Gang Chen. "Preparation of Poly-Hydrazide and Use as Pour Point Depressor for Heavy Oil." Materials Science Forum 943 (January 2019): 135–40. http://dx.doi.org/10.4028/www.scientific.net/msf.943.135.

Full text

Abstract:

To develop new pour point depressor, in this work, a poly-hydrazide is designed and prepared from vegetable oil, hydrazine hydrate and epichlorohydrin. The effectiveness of the poly-hydrazides on four crude oils was tested as pour point depressants as well as paraffin inhibiters. The results showed that the highest pour point reduction depression was achieved as 9.8°C with 2000ppm PH3O-3 in 2# crude oil. Below the pour point of the crude and processed oils, paraffin crystals will deposit and tend to plug flow lines and filters. The saturated hydrocarbons were separated, and the paraffin crysta

APA, Harvard, Vancouver, ISO, and other styles

5

Abidov, Musa T. "Pharmacological aspects of hydrazides and hydrazide derivatives." Health Promotion & Physical Activity 2, no. 3 (2017): 9–21. http://dx.doi.org/10.5604/01.3001.0010.7718.

Full text

Abstract:

Intense search for new antimicrobials, including anti-tuberculosis drugs, is dictated by the phenomenon of bacterial multidrug resistance. Hydrazides are considered the key intermediate and valuable starting material for some novel biologically active compounds. Over 70% of recently reported synthetic hydrazide derivatives are evaluated for antimicrobial and/or antifungal activity. The most frequently applied hydrazide is an anti- tuberculosis drug isoniazid/isonicotinic acid hydrazide (NIH). Hydrazide chemicals are sharing a common functional group characterized by a nitrogen- to-nitrogen cov

APA, Harvard, Vancouver, ISO, and other styles

6

Kantlehner, Willi, Jochen Mezger, Rüdiger Stieglitz, et al. "Orthoamide, LXV [1]. Kondensationsreaktionen von Amidinen, Guanidinen, Hydrazin und Hydrazin-Derivaten mit Orthoamiden von Alkincarbonsäuren / Orthoamides,LXV [1]. Condensation Reactions of Amidines, Guanidines, Hydrazine and Hydrazine Derivatives with Orthoamides of Alkyne Carboxylic Acids." Zeitschrift für Naturforschung B 62, no. 8 (2007): 1015–29. http://dx.doi.org/10.1515/znb-2007-0804.

Full text

Abstract:

The orthoamide derivatives 4 react with amidines 10 and guanidines 11 to give 4-dimethylaminopyrimidines 12. The 3-dimethylamino-pyrazoles 13a - c can be prepared from orthoamides 4 and hydrazine. The hydrazine derivative 14, whose constitution was established by crystal structure analysis, is obtained in low yield when hydrazine is added dropwise to a boiling solution of 4d in THF.Methyl- and phenylhydrazine, undergo reaction with the orthoamides 4a, c yielding mixtures of the isomeric pyrazoles 19 and 20. The reaction of 4c with acylhydrazines 21a - e affords the pyrazole 13b. The pyrazole 2

APA, Harvard, Vancouver, ISO, and other styles

7

Afsah, Elsayed M., Saad S. Elmorsy, Soha M. Abdelmageed, and Zaki E. Zaki. "Synthesis of some new hydrazide-hydrazones related to isatin and its Mannich and Schiff bases." Zeitschrift für Naturforschung B 71, no. 11 (2016): 1147–57. http://dx.doi.org/10.1515/znb-2016-0130.

Full text

Abstract:

AbstractThe hydrazide-hydrazones 6a–d and 7a, b were obtained by treating isatin (1) or its Mannich base 2 with hydrazides incorporating piperidine, morpholine, and piperazine units. The reaction of 1 and 2 with hydrazides related to triazenes having piperidine, morpholine, and 1,2,3,4-tetrahydroisoquinoline moieties gave 12a–c and 13a–c. Treatment of 1 and 2 with iminodiacetohydrazide (14) and ethylenediamine tetraacetohydrazide (18) afforded 15–17 and 19a, b, respectively. The Mannich reaction of the Schiff base 20 with formaldehyde and the appropriate hydrazide or bis(hydrazide) gave 21a, b

APA, Harvard, Vancouver, ISO, and other styles

8

Cai, Yan-Hua, and Shun-Jiang Li. "Synthesis and Performance ofN-(Benzoyl) Stearic Acid Hydrazide." E-Journal of Chemistry 9, no. 2 (2012): 545–52. http://dx.doi.org/10.1155/2012/514386.

Full text

Abstract:

N-(benzoyl) stearic acid hydrazide was synthesized from benzoyl hydrazine and stearyl chloride which was deprived from stearic acid via acylation. The structure of the compound had been characterized by FT-IR,1H NMR, at the same time, the structure of N-(benzoyl) stearic acid hydrazide was optimized by the semiempirical method PM3. The influence of the reaction ratio, reaction time and reaction temperature to the yield ofN-(benzoyl) stearic acid hydrazide was investigated by orthogonal experiment, and the optimized reaction condition was molar ratio of benzoyl hydrazine: stearyl chloride 1:1,

APA, Harvard, Vancouver, ISO, and other styles

9

Oinuma, Ken-Ichi, Atsushi Takuwa, Kosuke Taniyama, Yuki Doi, and Naoki Takaya. "Hydrazidase, a Novel Amidase Signature Enzyme That Hydrolyzes Acylhydrazides." Journal of Bacteriology 197, no. 6 (2015): 1115–24. http://dx.doi.org/10.1128/jb.02443-14.

Full text

Abstract:

The degradation mechanisms of natural and artificial hydrazides have been elucidated. Here we screened and isolated bacteria that utilize the acylhydrazide 4-hydroxybenzoic acid 1-phenylethylidene hydrazide (HBPH) from soils. Physiological and phylogenetic studies identified one bacterium asMicrobacteriumsp. strain HM58-2, from which we purified intracellular hydrazidase, cloned its gene, and prepared recombinant hydrazidase using anEscherichia coliexpression system. TheMicrobacteriumsp. HM58-2 hydrazidase is a 631-amino-acid monomer that was 31% identical to indoleacetamide hydrolase isolated

APA, Harvard, Vancouver, ISO, and other styles

10

Dzhumadullaeva, S. A., A. B. Bayeshov, and A. V. Kolesnikov. "STUDY OF THE CATALYTIC HYDRAZINOLYSIS OF HIGHER FATTY ACIDS." SERIES CHEMISTRY AND TECHNOLOGY 2, no. 440 (2020): 56–61. http://dx.doi.org/10.32014/2020.2518-1491.23.

Full text

Abstract:

In this work, the reaction of hydrazinolysis of higher fatty acid in the presence of an ionite catalyst is considered for the first time. Synthetic commodity anion exchange resin AB-17-8 was used as a catalyst. Before use, the anionite was converted to OH-form and its exchange capacity was determined. The experiments were made in the static conditions in a glass reactor with mixing of the reaction mixture.The reaction of palmitic acid with hydrazine yielded the corresponding hydrazide. The influence of various factors (quantity of hydrazine hydrate, catalyst, butyl alcohol, temperature, reacti

APA, Harvard, Vancouver, ISO, and other styles

11

Huang, Yi-Chao, Ge-Min Fang, and Lei Liu. "Chemical synthesis of proteins using hydrazide intermediates." National Science Review 3, no. 1 (2015): 107–16. http://dx.doi.org/10.1093/nsr/nwv072.

Full text

Abstract:

Abstract Protein chemical synthesis offers useful and otherwise-difficulty-to-obtain biomacromolecules for biological and pharmaceutical studies. Recently, the hydrazide chemistry has drawn attentions in this field as peptide or protein hydrazides can be used as key intermediates for different synthesis and modification purposes. Besides being a traditional bioorthogonal chemical handle, a hydrazide group can serve as a readily accessible precursor of a thioester. This strategy significantly improves the efficiency and scope of native chemical ligation for protein chemical synthesis. Here we r

APA, Harvard, Vancouver, ISO, and other styles

12

Varynskyi, B. О. "Optimization of detection range of hydrazides of carboxylic acids and 2-acylhydrazinсarbothioamids by HPLC-ECI-MC". Farmatsevtychnyi zhurnal, № 4 (4 вересня 2018): 59–64. http://dx.doi.org/10.32352/0367-3057.4.15.02.

Full text

Abstract:

Elaboration of control steps of hydrazids and сarbothioamids, raw materials in the synthesis of 1,2,4-triazol-3-yl-thioacetate acids, potential drug substances on research and production stage is an important task. The study of adsorption, distribution, metabolism and excretion of these substances has great importance. The HPLC-MS is the most universal and selective method used in these cases. The aim of our study was to determine the optimal conditions for mass spectrometric detection of ionization in electrospray in HPLC-MS іzonіcotinohydrazide, furan-2-carbohydrazide, 2-morpholinoacet

APA, Harvard, Vancouver, ISO, and other styles

13

Zhang, Xiaolai. "Oxidations of Benzhydrazide and Phenylacetic Hydrazide by Hexachloroiridate(IV): Reaction Mechanism and Structure–Reactivity Relationship." Molecules 25, no. 2 (2020): 308. http://dx.doi.org/10.3390/molecules25020308.

Full text

Abstract:

Benz(o)hydrazide (BH) is the basic aryl hydrazide; aryl hydrazides have been pursued in the course of drug discovery. Oxidations of BH and phenylacetic hydrazide (PAH) by hexachloroiridate(IV) ([IrCl6]2−) were investigated by use of stopped-flow spectral, rapid spectral scan, RP-HPLC and NMR spectroscopic techniques. The oxidation reactions followed well-defined second-order kinetics and the observed second-order rate constant k′ versus pH profiles were established over a wide pH range. Product analysis revealed that BH and PAH were cleanly oxidized to benzoic acid and phenylacetic acid, respe

APA, Harvard, Vancouver, ISO, and other styles

14

Johnson, Andrew L., Nathan Hollingsworth, Andrew Kingsley, Gabriele Kociok-Köhn, and Kieran C. Molloy. "Organocadmium Hydrazide and Hydrazine Complexes." Organometallics 28, no. 8 (2009): 2650–53. http://dx.doi.org/10.1021/om900121z.

Full text

APA, Harvard, Vancouver, ISO, and other styles

15

Yehye, Wageeh, and Amit Nath. "Acid Hydrazide: A Potential Reagent for the Synthesis of Semicarbazones." Synthesis 50, no. 21 (2018): 4301–12. http://dx.doi.org/10.1055/s-0037-1609557.

Full text

Abstract:

Complex semicarbazone derivatives were successfully synthesized from substituted semicarbazides in acidic ethanol upon heating in the presence of aldehyde. The reaction is functional group tolerant and chemoselective because no terminal hydrazine moiety is present in the substituted semicarbazides. Thus, functional groups such as esters and acetyls, which are prone to reaction with hydrazine, can also be used in this reaction because the terminal hydrazine moiety of the acid hydrazide was protected by aryl isocyanates in order to prepare substituted semicarbazides. In addition, neither of the

APA, Harvard, Vancouver, ISO, and other styles

16

Lupea, Xenia, Iuliana Popescu, Corneliu Tarabasanu, Ioana Ienascu, and Valentin Badea. "The synthesis and characterization of some ortho-substituted phenoxyalkanoic acids and their derivatives." Journal of the Serbian Chemical Society 71, no. 12 (2006): 1247–61. http://dx.doi.org/10.2298/jsc0612247l.

Full text

Abstract:

The synthesis of 2-phenoxyalkanoic acids (ethanoic, propanoic, butanoic) was realized by the reaction of ortho-hydroxybenzamide respectively N-phenyl-o-hydroxybenzamide with ?-halogenated acids in aqueous sodium hydroxide solution. 2-[o-(carbamoyl)phenoxy]-2-methyl- and 2-[o-(phenylcarbamoyl)phenoxy]-2-methyl- propanoic acids were obtained by reaction of the appropriate amide with acetone, chloroform and sodium hydroxide. Ethyl esters of 2-phenoxyalkanoic acids were obtained by the reaction of the amide with ethyl esters of ?-halogenated acids in different reaction media. Starting from the eth

APA, Harvard, Vancouver, ISO, and other styles

17

Androš Dubraja, Lidija, Ivanka Jerić, Andreas Puškarić, Josip Bronić, and Eufemio Moreno-Pineda. "Coordination ability of amino acid hydrazide ligands and their influence on magnetic properties in copper(ii) coordination polymers." CrystEngComm 20, no. 17 (2018): 2396–403. http://dx.doi.org/10.1039/c8ce00210j.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Khalifa, Nagy M., Ahmed M. Naglah, Mohamed A. Al-Omara, and Abd El-Galil E. Amr. "Synthesis and Reactions of New Chiral Linear Dipeptide Candidates Using Nalidixic Acid as Starting Material." Zeitschrift für Naturforschung B 69, no. 6 (2014): 728–36. http://dx.doi.org/10.5560/znb.2014-4031.

Full text

Abstract:

A series of dipeptide heterocyclic derivatives 4-15 were synthesized using methyl 2-{[(1-ethyl- 7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridin-3-yl)carbonyl]amino}-3-ethylbutanoate (3) as starting material. Treatment of 3 with L-phenylalanine methyl ester hydrochloride afforded the corresponding dipeptide methyl ester derivative 4, which was treated with hydrazine hydrate to afford the dipeptide acid hydrazide 5. Compound 5 was coupled with aldehyde and acetophenone derivatives to afford the corresponding Schiff bases 6a-f. The hydrazide derivative 5 was reacted with ethyl acetoacetate or acetone

APA, Harvard, Vancouver, ISO, and other styles

19

Chauhan, Pradeep S., Skye Brettell, Mulamreddy Ramakotaiah, et al. "Hydrazine derivative synthesis by trifluoroacetyl hydrazide alkylation." Canadian Journal of Chemistry 98, no. 9 (2020): 485–94. http://dx.doi.org/10.1139/cjc-2020-0052.

Full text

Abstract:

N′-Alkyl hydrazides were effectively synthesized by routes featuring installation, alkylation, and removal of a trifluoroacetyl group. A set of amino acid derived hydrazides were acylated using trifluoroacetic anhydride, and the resulting trifluoroacetyl hydrazides were alkylated with alcohols in Mitsunobu reactions and with alkyl halides under alkaline conditions. Removal of the trifluoroacetyl group was affected under reductive and hydrolytic conditions to provide the respective N′-alkyl hydrazides. This three-step process may be performed without isolation of intermediates to yield N′-alkyl

APA, Harvard, Vancouver, ISO, and other styles

20

Love, Dillon, Kangmin Kim, Dylan W. Domaille та ін. "Catalyst-free, aza-Michael polymerization of hydrazides: polymerizability, kinetics, and mechanistic origin of an α-effect". Polymer Chemistry 10, № 42 (2019): 5790–804. http://dx.doi.org/10.1039/c9py01199d.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Uhl, Werner, Jens Molter, and Rainer Koch. "Aluminium Hydrazides: Reactions oftert-Butylaluminium Chlorides with Dilithium Bis(trimethylsilyl)hydrazide – Formation of Iminoalanes and their Hydrazido Adducts." European Journal of Inorganic Chemistry 1999, no. 11 (1999): 2021–27. http://dx.doi.org/10.1002/(sici)1099-0682(199911)1999:11<2021::aid-ejic2021>3.0.co;2-u.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Wu, Shouting, Xi Liang, Fang Luo, et al. "Synthesis, Crystal Structure and Bioactivity of Phenazine-1-carboxylic Acylhydrazone Derivatives." Molecules 26, no. 17 (2021): 5320. http://dx.doi.org/10.3390/molecules26175320.

Full text

Abstract:

A phenazine-1-carboxylic acid intermediate was synthesized from the reaction of aniline and 2-bromo-3-nitro-benzoic acid. It was then esterified and reacted with hydrazine hydrate to afford phenazine-1-carboxylic hydrazine. Finally, 10 new hydrazone compounds 3a–3j were obtained by the condensation reaction of phenazine-1-carboxylic acid hydrazide and the respective aldehyde-containing compound. The structures were characterized by 1H and 13C NMR spectroscopy, MS and single crystal X-ray diffraction. The antitumor activity of the target compounds in vitro (HeLa and A549) was determined by thia

APA, Harvard, Vancouver, ISO, and other styles

23

Dzhumadullaeva, S. A., A. B. Bayeshov, and A. V. Kolesnikov. "THE KINETICS OF SELECTIVE HYDRAZINOLYSIS OF MALEIC ACID ON THE ACID CATALYST." SERIES CHEMISTRY AND TECHNOLOGY 2, no. 446 (2021): 53–57. http://dx.doi.org/10.32014/2021.2518-1491.26.

Full text

Abstract:

For the first time, kinetics and the mechanism of the reaction of hydrazinolysis of maleic acid in the presence of cation exchanger resin KU-2-8 in H-form have been studied. The experiments were carried out in a static system in a thermostat glass reactor. It was found that cation exchanger shows high catalytic activity in the studied process - maleic acid conversion was 93%, and maleic hydrazide yield was 90%. The conversion selectivity of maleic acid to maleic hydrazide was 97,8%. The reaction rate was determined from the accumulation of maleic hydrazide. The apparent reaction rate constant

APA, Harvard, Vancouver, ISO, and other styles

24

Sarma, K. Narasimha, M. C. S. Subha, and K. Chowdoji Rao. "A Facial Synthesis and Antimicrobial Activity of Some Pyrazole Derivatives Carrying Indole." E-Journal of Chemistry 7, no. 3 (2010): 745–50. http://dx.doi.org/10.1155/2010/979401.

Full text

Abstract:

The title compounds (7a-h) were prepared by esterification of indole-5-carboxylic acid (1) and subsequent treatment with hydrazine hydrate in methanolviathe hydrazide (3). Finally hydrazide (3) condensed with different substituted aldol (6) in acetic acid / PTSA catalytic media produced (3,5-subsituted-4,5-dihydropyrazol-1-yl)(1H-indol-5-yl)methanone (7a-h) in good yields. All the newly synthesized compounds are by elemental analysis and spectral studies and evaluated for antimicrobial activities.

APA, Harvard, Vancouver, ISO, and other styles

25

Jana, Surajit, Roland Fröhlich, and Norbert W. Mitzel. "Zinc Hydrazides and Hydrazide-Alkoxides with Cyclic and Acyclic Hydrazide Substituents." Zeitschrift für anorganische und allgemeine Chemie 634, no. 9 (2008): 1477–84. http://dx.doi.org/10.1002/zaac.200800144.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

Słomiak, Krzysztof, Andrzej Łazarenkow, Lilianna Chęcińska, Joachim Kusz, Justyn Ochocki, and Jolanta Nawrot-Modranka. "Synthesis, Spectroscopic Analysis and Assessment of the Biological Activity of New Hydrazine and Hydrazide Derivatives of 3-Formylchromone." Molecules 23, no. 8 (2018): 2067. http://dx.doi.org/10.3390/molecules23082067.

Full text

Abstract:

The hydrazine and hydrazide derivatives of benzo-γ-pyrones with fluorine substituents remain an unexplored group of chemical compounds. This preliminary study reports the synthesis, structural assessment, initial microbiological screening and biological testing of the synthesized compounds on cell lines using the XTT-assay. A series of 10 novel hydrazine and hydrazide derivatives of 3-formylchromone were synthesized and their structures determined. Structural assessment consisted of elemental analysis, IR, 1H-NMR, 13C-NMR, MS and crystallographic studies. Antimicrobial activity was tested on s

APA, Harvard, Vancouver, ISO, and other styles

27

Wei, Tai-Bao, Hong Liu, Man-Lin Li, and You-Ming Zhang. "A Rapid and High-yield Synthesis of Aryloxyacetyl Hydrazides under Microwave Irradiation and with Phase Transfer Catalysis." Journal of Chemical Research 2005, no. 7 (2005): 432–33. http://dx.doi.org/10.3184/030823405774309177.

Full text

Abstract:

A series of aryloxyacetyl hydrazides 4a–l were synthesised under microwave irradiation and phase transfer catalysis conditions. By the optimisation of the reaction conditions, a rapid, high-yield and efficient method for the preparation of aryloxyacetyl hydrazide was given.

APA, Harvard, Vancouver, ISO, and other styles

28

Josephrajan, T., and V. T. Ramakrishnan. "Thermal and microwave assisted synthesis of N-aroylamino acridinediones." Canadian Journal of Chemistry 85, no. 9 (2007): 572–75. http://dx.doi.org/10.1139/v07-075.

Full text

Abstract:

A series of N-aroylamino acridinediones (3a–3d and6a–6e) have been synthesized from tetraketones (1 and 4) and benzoic hydrazides (2a–2d and 5a–5e) under thermal and microwave irradiation conditions with solid supports.Key words: acridine, hydrazide, microwave irradiation.

APA, Harvard, Vancouver, ISO, and other styles

29

Johnson, Andrew L., Nathan Hollingsworth, Andrew Kingsley, Gabriele Kociok-Köhn, and Kieran C. Molloy. "New Organocadmium Hydrazine Adducts and Hydrazide Complexes." European Journal of Inorganic Chemistry 2012, no. 2 (2011): 246–50. http://dx.doi.org/10.1002/ejic.201100885.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Suzuki, Ichiro, Ai Hirata та Kei Takeda. "Development of Cyclic Hydrazine and Hydrazide Type Organocatalyst ⎯ Mechanistic Aspects of Cyclic Hydrazine/Hydrazide-Catalyzed Diels-Αlder Reactions". HETEROCYCLES 79, № 1 (2009): 851. http://dx.doi.org/10.3987/com-08-s(d)54.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Drev, Miha, Uroš Grošelj та Jurij Svete. "Transformations of β-aryl-N-Cbz-α,β-didehydro-α-amino esters with hydrazine hydrate". Zeitschrift für Naturforschung B 71, № 6 (2016): 623–31. http://dx.doi.org/10.1515/znb-2015-0221.

Full text

Abstract:

AbstractCyclizations of Cbz-protected α,β-didehydro-β-arylalanine esters 1 with excess hydrazine hydrate afforded mixtures of the expected 3-pyrazolidinones 2 and the unexpected 1-amino-5-benzylidenehydantoins 6 and N-Cbz-β-arylalanine hydrazides 7. Presumably, the pyrazolidinones 2 and hydantoins 6 are formed as primary products via competitive 1,2- and 1,4-addition of hydrazine hydrate followed by cyclization, whereas β-arylalanine hydrazides 7 are formed as secondary products via reductive cleavage of the C(5)–N(1) bond in pyrazolidinones 2. The overall selectivity depends on the reaction t

APA, Harvard, Vancouver, ISO, and other styles

32

Ienascu, Ioana M. c., Alfa X. Lupea, Iuliana M. Popescu, Stefan Th Tomas, and Alina D. Zamfir. "Synthesis and Characterization of Some New 2-Hydroxy-N-(3-Trifluoromethyl-Phenyl)-Benzamide Derivatives." Revista de Chimie 59, no. 1 (2008): 56–60. http://dx.doi.org/10.37358/rc.08.1.1707.

Full text

Abstract:

In the reaction between 2-hydroxy-N-(3-trifluoromethyl-phenyl)-benzamide and chloro-acetic acid ethyl ester, [2-(3-trifluoromethyl-phenylcarbamoyl)-phenoxy]-acetic acid ethyl ester was obtained. The ethyl ester was condensed with hydrazine giving 2-hydrazinocarbonylmethoxy-N-(3-trifluoromethyl-phenyl)-benzamide. This hydrazide is considered the key intermediate for the synthesis of new compounds. So, in the reaction between hydrazide and chloro-substituted benzaldehydes hydrazones were obtained. In order to establish their structures, all new synthesized compounds were analyzed by modern physi

APA, Harvard, Vancouver, ISO, and other styles

33

Aouad, Mohamed Reda, Mouslim Messali, Nadjet Rezki, Adeeb Al-Sheikh Ali, and Alain Lesimple. "Synthesis and characterization of some novel 1,2,4-triazoles, 1,3,4-thiadiazoles and Schiff bases incorporating imidazole moiety as potential antimicrobial agents." Acta Pharmaceutica 65, no. 2 (2015): 117–32. http://dx.doi.org/10.1515/acph-2015-0011.

Full text

Abstract:

Abstract (1,4,5-Triphenylimidazol-2-yl-thio)butyric acid hydrazide (3) was obtained via alkylation of 1,4,5-triphenylimidazol-2- thiol (1) with ethylbromobutyrate, followed by addition of hydrazine hydrate. Treatment of acid hydrazide 3 with carbon disulfide in an ethanolic potassium hydroxide solution gave the intermediate potassium dithiocarbazinate salt, which was cyclized to 4-amino-5-[(1,4,5-triphenylimidazol- -2-yl)thiopropyl]-2H-1,2,4-triazole-3-thione (4) in the presence of hydrazine hydrate. Condensation of compound 3 with alkyl/arylisothiocyanate afforded the corresponding 1-[4-(1,4,

APA, Harvard, Vancouver, ISO, and other styles

34

Panea, I., Lucia Bodochi, Teodora Panea, Daniela Zinveliu, and Violeta Pascalau. "BIOLOGICAL ACTIVE ACYLHYDRAZIDE I. THE O-ACYL-DERIVATIVES NATURE OF MONOACYLATION PRODUCTS OF CYCLIC MALEIC- AND PHTHALIC-HYDRAZIDE." SOUTHERN BRAZILIAN JOURNAL OF CHEMISTRY 7, no. 8 (1999): 25–40. http://dx.doi.org/10.48141/sbjchem.v7.n8.1999.27_1999.pdf.

Full text

Abstract:

We confirmed, on the basis of chemical and physicochemical (melting points, IR- and 1H-NMR-spectra) data, that the products isolated by monoacylation of cyclic maleic- and phthalic-hydrazides have only the O-acyl derivatives nature although owing to tautomerism. These hydrazides may give rise to N- or/and O-acyl derivatives in such reactions. Simultaneously, we showed that the claims for the obtainment of N-acyl derivatives of cyclic maleic- and phthalic-hydrazides were not valid. Also by reacting the cyclic maleic-, respectively phthalic-hydrazide, with 4-chlorobenzoylchloride two new O-monoa

APA, Harvard, Vancouver, ISO, and other styles

35

Madkour, H., M. R. Mahmoud Mahmoud, A. Sakr, and M. Habashy. "SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF NEW 4H-PYRANO [3,2-h]QUINOLINES AND FUSED DERIVATIVES." Scientia Pharmaceutica 69, no. 1 (2001): 33–52. http://dx.doi.org/10.3797/scipharm.aut-01-05.

Full text

Abstract:

The starting materials, 2-amino-3-cyano-4-(3,4,5-trimethoxyphenyl)-4H-pyran0[3,2-hlquinoline 1 and ethyl-2-amino-4-(3,4,5-trimethoxyphenyl)-4H-pyrano [3,2-hlquinolin-3-carboxylate 2 were synthesised from 8-hydroxyquinoline and a-cyano-3,4,5-trimethoxycinnamonitrileand/or ethyl-a-cyano-3,4,5-trimethoxy-cinnamatre respectively. In order to construct a third heterocyclic ring 1 and 2were condensed with ethyl bromoacetate, formarnide, carbon disulfide to afford pyrrolo-, pyrimido- and thiazinopyranoquinolines 3-6respectively. The S-alkylated products 7 and 8 were obtained by the effect of chloroac

APA, Harvard, Vancouver, ISO, and other styles

36

Pagar, Balasaheb P. "Synthesis and Antimicrobial Activity of Novel Oxothiazolidine Derivatives." Asian Journal of Organic & Medicinal Chemistry 5, no. 2 (2020): 91–96. http://dx.doi.org/10.14233/ajomc.2020.ajomc-p248.

Full text

Abstract:

In this article, acid hydrazide 2, a functional group, was synthesized by the reaction of (4-chloro-12- methyl-16,17-dihydro-15-thia-6,11-diaza-cyclopenta[a]phenanthren-7-ylsulfanyl)acetic acid ethyl ester (1) with hydrazine yield (4-chloro-12-methyl-16,17-dihydro-15-thia-6,11-diazacyclopenta[a]- phenanthren-7-ylsulfanyl)acetic acid hydrazide (2) is discussed. The reactive acid hydrazide compound 2 was utilized for the synthesis of amides 3, Schiff’s bases 4 and thiazolidine 5 derivatives. The structures of target compounds were confirmed by elemental analysis and spectral data. The antimicrob

APA, Harvard, Vancouver, ISO, and other styles

37

Salem, Shereen E., Esam A. Gomaa, Mohamed M. El-Defrawy, and Noha M. Ebrahem. "Studies on the Complexation of Succinic Hydrazide with Copper Chloride Salt." European Journal of Advanced Chemistry Research 2, no. 1 (2021): 14–20. http://dx.doi.org/10.24018/ejchem.2021.2.1.40.

Full text

Abstract:

The electrochemical behavior of the complexation between copper chloride salt and succinic hydrazide can be explained using cyclic voltammetric measurements. The complex is formed through the interaction with nitrogen and hydroxyl group or carbonyl group of succinic hydrazides. This interaction can be observed by decreasing in the height peak of current and measuring the (anodic/cathodic) shift of the potentials. All the solvation and thermodynamic parameters for the interaction of copper ions with succinic hydrazide as stability constant, Gibbs free energies, enthalpies and entropies of inter

APA, Harvard, Vancouver, ISO, and other styles

38

Darwish, Elham S., Mahmoud A. Abdelrahman, and Abdellatif M. Salaheldin. "Enamines in Heterocyclic Synthesis: A Novel Simple and Efficient Route to Condensed Pyridazines." Zeitschrift für Naturforschung B 66, no. 6 (2011): 597–602. http://dx.doi.org/10.1515/znb-2011-0607.

Full text

Abstract:

An efficient and easy preparation of enamine derivatives, via active methyl and methylene compounds by in situ-generated 1-(diethoxymethyl)piperidine, produced from the mixture of triethyl orthoformate/piperidine/DMF, are described. Some new pyridazinone derivatives have been synthesized from the reaction of enamines with hydrazine hydrate and cyanoacid hydrazide.

APA, Harvard, Vancouver, ISO, and other styles

39

Riggs, Anthony S., David M. Borth, David G. Tutty, et al. "Determination of Hydrazine in Maleic Hydrazide Technical and Pesticide Formulations by Gas Chromatography: Collaborative Study." Journal of AOAC INTERNATIONAL 91, no. 1 (2008): 5–12. http://dx.doi.org/10.1093/jaoac/91.1.5.

Full text

Abstract:

Abstract Twelve collaborating laboratories assayed hydrazine in technical maleic hydrazide (MH), 6-hydroxy-2H-pyridazin-3-one, and 2 formulated products, a liquid concentrate and a soluble granule, using gas chromatography (GC) with electron capture detection. The hydrazine content in the samples ranged from 0.03 ppm, in the liquid concentrate, to 0.26 ppm, in MH technical. Hydrazine and MH are dissolved in an aqueous solution. The MH is then precipitated out of solution by acidification. The solution containing hydrazine is treated with excess pentafluorobenzaldehyde (PFB) to form pentafluoro

APA, Harvard, Vancouver, ISO, and other styles

40

Timperio, Anna Maria, Sara Rinalducci, and Lello Zolla. "Hydrazide derivatives produce active oxygen species as hydrazine." Bioorganic Chemistry 33, no. 6 (2005): 459–69. http://dx.doi.org/10.1016/j.bioorg.2005.09.001.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Tokumaru, Kazuyuki, Kalisankar Bera, and Jeffrey Johnston. "1,3,4-Oxadiazole and Heteroaromatic-Fused 1,2,4-Triazole Synthesis Using Diverted Umpolung Amide Synthesis." Synthesis 49, no. 20 (2017): 4670–75. http://dx.doi.org/10.1055/s-0036-1590802.

Full text

Abstract:

Umpolung Amide Synthesis (UmAS) has emerged as a superior alternative to conventional amide synthesis methods based on carbonyl electrophiles in a range of situations, particularly when epimerization-prone couplings are prescribed. In an unanticipated development during our most recent studies, we discovered that diacyl hydrazide products from UmAS were not formed as intermediates when using an acyl hydrazide as the amine acceptor. This resulted in a new preparation of 1,3,4-oxadiazoles from α-bromonitroalkane donors. We hypothesized that a key tetrahedral intermediate in UmAS was diverted tow

APA, Harvard, Vancouver, ISO, and other styles

42

Bhat, M., S. L. Belagali, N. K. H. Kumar, and S. Jagannath. "Anti-mitotic Activity of the Benzothiazole-pyrazole Hybrid Derivatives." Anti-Infective Agents 17, no. 1 (2018): 66–73. http://dx.doi.org/10.2174/2211352516666180914101758.

Full text

Abstract:

Background: Nitrogen-containing heterocyclics are abundant in natural products and also in synthetic drug molecules because of a variety of applications and superior pharmacological profile action. Pyrazoles are the integral architects of many of the heterocyclic compounds with superior biological activity. Methods: Two series of the pyrazole conjugated Benzothiazole derivatives were synthesized. The pyrazoles were synthesized by the Vilsmeier-Haack reaction and then conjugated with benzothiazole hydrazine and hydrazide by imine bond formation. The synthesized compounds were screened for anti-

APA, Harvard, Vancouver, ISO, and other styles

43

Journal, Baghdad Science. "Synthesis of New Heterocyclic Derivatives from 4-(3, 5-Dimethyl-1-phenyl-1H-pyrazol-4-ylazo)- benzoic acid." Baghdad Science Journal 7, no. 1 (2010): 727–36. http://dx.doi.org/10.21123/bsj.7.1.727-736.

Full text

Abstract:

In this work pyrazolin derivatives were prepared from the diazonium chloride salt of 4-aminobenzoic acid. Azo compounds were prepared from the reaction of an ethanolic solution of sodium acetate and calculated amount of active methylene compound namely, acetyl acetone to obtain the corresponding hydrazono derivative (1). Cyclocondensation reaction of compounds (1) with hydrazine hydrate and phenyl hydrazine in boiling ethanol affording the corresponding pyrazoline-5-one derivatives of 4-aminobenzoic acid (2,3). Then compound (3) was reacted with thionyl chloride to give the corresponding acid

APA, Harvard, Vancouver, ISO, and other styles

44

Mahmoud, Mahmoud R., Eman A. A. El-Bordany, Naglaa F. Hassan, and Fatma S. M. Abu El-Azm. "New 2,3-Disubstituted Quinazolin-4(3H)-Ones from 2-Undecyl-3,1-Benzoxazin-4-One." Journal of Chemical Research 2007, no. 9 (2007): 541–44. http://dx.doi.org/10.3184/030823407x248315.

Full text

Abstract:

2-undecyl-4H-3,1-benzoxazin-4-one (2) was prepared and reacted with primary and secondary amines affording compounds 3–7, while with hydrazine hydrate it gave the quinazolinone derivative 8. The reaction of 8 with 3,4,5-trimethoxybenzaldehyde followed by thioglycollic acid yielded 9 and 10, respectively. Acylation of 8 using cinnamoyl chloride gave 11. Furthermore, treatment of 2 with hydrazine derivatives provided 12 and 13. Fusion of 2 with ammonium acetate gave the quinazolinone derivative 14 which upon treatment with ethyl chloroacetate yielded the ester 15. The hydrazide 17 was obtained f

APA, Harvard, Vancouver, ISO, and other styles

45

Nayak, Riddhi A., and Anvita D. Mangte. "Synthesis and Antimicrobial Studies of Novel N-Glycosyl Hydrazino Carbothioamide." Asian Journal of Chemistry 33, no. 1 (2020): 127–31. http://dx.doi.org/10.14233/ajchem.2021.22967.

Full text

Abstract:

In view of applications of N-glycosylated compounds in medicinal chemistry and in many other ways, herein the synthesis of novel N-glycosyl hydrazino carbothioamides is reported. New N-glycosyl hydrazino carbothioamides were synthesized by the condensation of per-O-acetyl glycosyl isothiocyanate with different aromatic hydrazides. The newly synthesized compounds were characterized by using the IR, 1H NMR and mass spectral studies. Antimicrobial evaluation of the synthesized N-glycosyl hydrazino carbothioamide was also examined. Antimicrobial activities of the synthesized compound were evaluate

APA, Harvard, Vancouver, ISO, and other styles

46

Lerner, Hans-Wolfram, Nils Wiberg, Michael Bolte, H. Nöth, and J. Knizek. "Supersilyliertes Ammoniak und supersilyliertes Hydrazin: Synthese, Struktur und Eigenschaften / Supersilyl Ammonia and Supersilyl Hydrazine: Synthesis, Structure and Properties." Zeitschrift für Naturforschung B 57, no. 2 (2002): 177–82. http://dx.doi.org/10.1515/znb-2002-0208.

Full text

Abstract:

An excellent supersilylation agent, supersilyl triflate, tBu3SiO3SCF3, is easily obtained from tBu3SiH and CF3SO3H. Supersilyl triflate, tBu3SiO3SCF3, reacts with lithium amide or lithium hydrazide to form the supersilyl amine, tBu3SiNH2, or the supersilyl hydrazines, tBu3SiNHNH2 and tBu3SiNH-HNSitBu3, respectively. The structures of supersilyl triflate, tBu3SiO3SCF3, and bissupersilyl hydrazine, tBu3SiNH-HNSitBu3, have been determined by X-ray structure analysis.

APA, Harvard, Vancouver, ISO, and other styles

47

Salam, Osama I. Abdel, Mohamed A. Al-Omar, Nagy M. Khalifa, Abd El-Galil E. Amr, and Mohamed M. Abdallah. "Analgesic and Anticonvulsant Activities of Some Newly Synthesized Trisubstituted Pyridine Derivatives." Zeitschrift für Naturforschung C 68, no. 7-8 (2013): 264–68. http://dx.doi.org/10.1515/znc-2013-7-802.

Full text

Abstract:

A series of novel pyridine carbohydrazide derivatives were synthesized from the reaction of 2-chloro-6-hydrazino-isonicotinic acid hydrazide with selected active reagents. All prepared compounds were tested as analgesic and anticonvulsant agents. The pharmacological screening showed that many of these compounds have good activities comparable to those of valdecoxib and carbamazepine as reference drugs

APA, Harvard, Vancouver, ISO, and other styles

48

Vo, Thao T., and Jean'ne M. Shreeve. "1,1-Diamino-2,2-dinitroethene (FOX-7) and 1-amino-1-hydrazino-2,2-dinitroethene (HFOX) as amphotères: bases with strong acids." Journal of Materials Chemistry A 3, no. 16 (2015): 8756–63. http://dx.doi.org/10.1039/c4ta07098d.

Full text

Abstract:

The exciting discovery of the first cations based on 1,1-diamino-2,2-dinitroethene (FOX-7) and its hydrazine derivative, 1-amino-1-hydrazino-2,2-dinitroethene (HFOX), along with their syntheses and full characterization is described.

APA, Harvard, Vancouver, ISO, and other styles

49

Gera, Ankur, Chander Mohan, and Sandeep Arora. "Synthesis of Phthaloylglycyl Hydrazide Derivatives: Selective Protection of Phthalimide Group from Hydrazinolysis." Current Organic Synthesis 15, no. 6 (2018): 839–45. http://dx.doi.org/10.2174/1570179415666180601083256.

Full text

Abstract:

Background: N-phthalimide amino acid hydrazide is a class of compounds that have the potential therapeutic use. In general, hydrazinolysis of N-substituted amino acid(s) ester removes the ester group and yields the corresponding hydrazide. However, in case if N-substitution group is phthalimide, phthalimide group is cleaved and not the ester group. The resulted compound, therefore, is amino acid ester rather than Nphthalimide amino acid hydrazide. The above class of compounds, because of susceptibility of phthalimide group to hydrazinolysis, has previously been synthesized by a lengthy three-s

APA, Harvard, Vancouver, ISO, and other styles

50

Journal, Baghdad Science. "The preparation and characterization of some metal complexes with tridentate ONO ligand derived from phenyl hydrazine." Baghdad Science Journal 8, no. 3 (2011): 796–805. http://dx.doi.org/10.21123/bsj.8.3.796-805.

Full text

Abstract:

The phenyl hydrazine was react readily with acetic acid chloride in [1:2] ratio in alkyl of ethanolic solution, and refluxe for five hours to produce a new ligand of (N-Carboxymethyl-N-phenyl-hydrazino)-acetic acid [H2L].

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!