Academic literature on the topic 'Hydrazine carboxylic acid'

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Journal articles on the topic "Hydrazine carboxylic acid"

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Wu, Shouting, Xi Liang, Fang Luo, et al. "Synthesis, Crystal Structure and Bioactivity of Phenazine-1-carboxylic Acylhydrazone Derivatives." Molecules 26, no. 17 (2021): 5320. http://dx.doi.org/10.3390/molecules26175320.

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A phenazine-1-carboxylic acid intermediate was synthesized from the reaction of aniline and 2-bromo-3-nitro-benzoic acid. It was then esterified and reacted with hydrazine hydrate to afford phenazine-1-carboxylic hydrazine. Finally, 10 new hydrazone compounds 3a–3j were obtained by the condensation reaction of phenazine-1-carboxylic acid hydrazide and the respective aldehyde-containing compound. The structures were characterized by 1H and 13C NMR spectroscopy, MS and single crystal X-ray diffraction. The antitumor activity of the target compounds in vitro (HeLa and A549) was determined by thia
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Elshaarawy, Reda F. M., and Christoph Janiak. "2-Thiophenecarbohydrazides: A Novel Efficient Method for the Synthesis of 2-Thiophenecarbohydrazide." Zeitschrift für Naturforschung B 66, no. 12 (2011): 1202–8. http://dx.doi.org/10.1515/znb-2011-1202.

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Hydrazinolysis of carboxylic acid esters in alcoholic solutions is the standard method for preparing carbohydrazides (carboxylic hydrazides). Here we report an efficient process, involving the reaction of activated esters or amides with hydrazine, for the preparation of thiophenecarbohydrazides in yields larger than 90% and high purity. With this new method, a series of heteroaryl-, aryl-, or aralkyl- substituted carbohydrazides were synthesized and characterized. The X-ray crystal structure of 2-thiophenecarbohydrazide (thiophene-2-carboxylic hydrazide, 2-thenoyl-hydrazine) has revealed that
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Hamada, Nagwa M. M., Sohila H. Mancy, and Mohamed A. El Sekily. "A Facile Synthesis, Spectroscopic Identification, and Antimicrobial Activities of Some New Heterocyclic Derivatives from D-erythro-2,3-hexodiuloso-1,4-lactone-2-(o-chlorophenyl hydrazone)-3-oxime." International Journal of Chemistry 16, no. 2 (2024): 62. http://dx.doi.org/10.5539/ijc.v16n2p62.

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A new series of different heterocyclic derivatives was prepared via a facile unimolecular condensation of D-iso ascorbic acid with o-chlorophenyl hydrazine to give D-erythro-2,3-hexodiulosono-1,4-lactone 2-( o-chlorophenyl hydrazine (2). Reactions of (2) with hydroxylamine gave the 2-( o-chlorophenyl hydrazone)-3-oxime (3). On boiling with boiling acetyl chloride, (3) gave 2-o-chlorophenyl-4-(2,3-di-O-acetyl-D-erythro-glyceryl-1-yl)-1,2,3-triazole-5-carboxylic acid-5,1́-lactone (4). In the treatment of (3) with benzoyl chloride in pyridine the same dehydrati
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Hamada, Nagwa M. M., Sohila H. Mancy, and Mohamed A. El Sekily. "A Facile Synthesis, Spectroscopic Identification, and Antimicrobial Activities of Some New Heterocyclic Derivatives from D-erythro-2,3-hexodiuloso-1,4-lactone-2-(o-chlorophenyl hydrazone)-3-oxime." International Journal of Chemistry 17, no. 2 (2025): 50. https://doi.org/10.5539/ijc.v17n2p50.

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A new series of different heterocyclic derivatives was prepared via a facile unimolecular condensation of D-iso ascorbic acid with o-chlorophenyl hydrazine to give D-erythro-2,3-hexodiulosono-1,4-lactone 2-( o-chlorophenyl hydrazine (2). Reactions of (2) with hydroxylamine gave the 2-( o-chlorophenyl hydrazone)-3-oxime (3). On boiling with boiling acetyl chloride, (3) gave 2-o-chlorophenyl-4-(2,3-di-O-acetyl-D-erythro-glyceryl-1-yl)-1,2,3-triazole-5-carboxylic acid-5,1́-lactone (4). In the treatment of (3) with benzoyl chloride in pyridine the same dehydrati
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Gera, Ankur, Chander Mohan, and Sandeep Arora. "Synthesis of Phthaloylglycyl Hydrazide Derivatives: Selective Protection of Phthalimide Group from Hydrazinolysis." Current Organic Synthesis 15, no. 6 (2018): 839–45. http://dx.doi.org/10.2174/1570179415666180601083256.

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Background: N-phthalimide amino acid hydrazide is a class of compounds that have the potential therapeutic use. In general, hydrazinolysis of N-substituted amino acid(s) ester removes the ester group and yields the corresponding hydrazide. However, in case if N-substitution group is phthalimide, phthalimide group is cleaved and not the ester group. The resulted compound, therefore, is amino acid ester rather than Nphthalimide amino acid hydrazide. The above class of compounds, because of susceptibility of phthalimide group to hydrazinolysis, has previously been synthesized by a lengthy three-s
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Rai, K. M. Lokanatha, K. B. Umesha, and M. A. Harish Nayaka. "Antioxidant and Antimicrobial Activity of 5-methyl-2-(5-methyl-1,3-diphenyl-1H-pyrazole-4-carbonyl)-2,4-dihydro-pyrazol-3-one." International Journal of Biomedical Science 5, no. 4 (2009): 359–68. http://dx.doi.org/10.59566/ijbs.2009.5359.

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Cycloaddition of nitrile imines 4 generated in situ by the catalytic dehydrogenation of diphenyl hydrazones 3 using Chloramine-T (CAT) as oxidant in glacial acetic acid with enolic form of ethyl acetoacetate 5 afforded Ethyl 3-aryl-5-methyl-1-phenyl-1H-pyrazol-4-carboxylate 6 in 80% yield. The said pyrazoles 6 refluxed with 80% hydrazine hydrate using absolute alcohol as solvent for about 2-3 hours to produce the respective 5-methyl-1,3-diphenyl-1H-pyrazole-4-carboxylic acid hydrazide 7. The alcoholic solution of pyrazole acid hydrazides on heating with ethyl acetoacetate 5 to give the 5-methy
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Journal, Baghdad Science. "Synthesis of New Heterocyclic Derivatives from 4-(3, 5-Dimethyl-1-phenyl-1H-pyrazol-4-ylazo)- benzoic acid." Baghdad Science Journal 7, no. 1 (2010): 727–36. http://dx.doi.org/10.21123/bsj.7.1.727-736.

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In this work pyrazolin derivatives were prepared from the diazonium chloride salt of 4-aminobenzoic acid. Azo compounds were prepared from the reaction of an ethanolic solution of sodium acetate and calculated amount of active methylene compound namely, acetyl acetone to obtain the corresponding hydrazono derivative (1). Cyclocondensation reaction of compounds (1) with hydrazine hydrate and phenyl hydrazine in boiling ethanol affording the corresponding pyrazoline-5-one derivatives of 4-aminobenzoic acid (2,3). Then compound (3) was reacted with thionyl chloride to give the corresponding acid
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M.A., EI-Sekily, E. Elba M., and S. Fouad F. "Some heterocycles from dehydro-L-ascorbic acid and dehydro-D-isoascorbic acid." Journal of Indian Chemical Society Vol. 77, Mar 2000 (2000): 168–71. https://doi.org/10.5281/zenodo.5867557.

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Department of Chemistry, Faculty of Science, Alexandria, Egypt Department of Physics and Chemistry, Faculty of Education, Damanhour, Alexandria University, Egypt <em>Manuscript received 5 January 1999, revised 7 September 1999, accepted 13 September 1999</em> Reaction of D-<em>erythro</em>-2,3-hexodiulosono-1,4-lactone-2-phenylhydrazone 1 with <em>p</em>-sulfamylphenylhydrazine gives the 3-<em>p</em>&shy;sulfamylphenylhydrazone 2, which upon treatment with hydrazine hydrate or CuCl<sub>2</sub> affords pyrazolinedione 4 or 3,6-anhydro derivative 6, respectively. Condensation of the aldehyde 8 w
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Sarma, K. Narasimha, M. C. S. Subha, and K. Chowdoji Rao. "A Facial Synthesis and Antimicrobial Activity of Some Pyrazole Derivatives Carrying Indole." E-Journal of Chemistry 7, no. 3 (2010): 745–50. http://dx.doi.org/10.1155/2010/979401.

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The title compounds (7a-h) were prepared by esterification of indole-5-carboxylic acid (1) and subsequent treatment with hydrazine hydrate in methanolviathe hydrazide (3). Finally hydrazide (3) condensed with different substituted aldol (6) in acetic acid / PTSA catalytic media produced (3,5-subsituted-4,5-dihydropyrazol-1-yl)(1H-indol-5-yl)methanone (7a-h) in good yields. All the newly synthesized compounds are by elemental analysis and spectral studies and evaluated for antimicrobial activities.
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Martin, Alex. "Synthesis, Characterization and Screening of Anti-tubercular activity of 2, 5-Disubstituted-1, 3, 4-Oxadiazole." Indian Journal of Pharmaceutical and Biological Research 1, no. 03 (2013): 12–19. http://dx.doi.org/10.30750/ijpbr.1.3.3.

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The synthesis of 2-furyl-5-(substituted)-1,3,4-oxadiazoles was carried out by microwave irradiation of 2-furoic acid and ethanol followed by subsequent hydrazinolysis with hydrazine hydrate. Finally furan-2-acid hydrazide was treated with appropriate carboxylic acid in the presence of phosphorous oxychloride to produce title compounds. The structures of the newly synthesized compounds were established on the basis of spectral analysis such as IR, H1NMR and Mass spectral data. The synthesized compounds were screened for their anti-tubercular activity.
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Dissertations / Theses on the topic "Hydrazine carboxylic acid"

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Khan, Azra Nasir. "Novel solid-phase strategies for the synthesis of polyamines and atypical peptides." Thesis, University of Nottingham, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.311758.

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Karimi, Farhad. "[11C]Carbon Monoxide in Palladium- / Selenium-Promoted Carbonylation Reactions : Synthesis of 11C-Imides, Hydrazides, Amides, Carboxylic Acids, Carboxylic Esters, Carbothioates, Ketones and Carbamoyl Compounds." Doctoral thesis, Uppsala universitet, Avdelningen för organisk kemi, 2002. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2931.

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[11C]Carbon monoxide in low concentrations has been used in palladium- or seleniummediated carbonylation reactions such as the synthesis of 11C-imides, hydrazides, amides, carboxylic acids, esters, carbothioates, ketones and carbamoyl compounds. In these reactions aryl iodides have been used in most cases. However, less reactive aryl triflate, chloride and bromides were activated using tetrabutylammonium iodide. The reactivities of nucleophiles may have influence on the radiochemical yield of the 11Clabelled compounds. Carboxyamination of aryl halides using aniline derivatives yielded 10% of t
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Karimi, Farhad. "[11C]Carbon Monoxide in Palladium- / Selenium-Promoted Carbonylation Reactions : Synthesis of 11C-Imides, Hydrazides, Amides, Carboxylic Acids, Carboxylic Esters, Carbothioates, Ketones and Carbamoyl Compounds." Doctoral thesis, Uppsala University, Organic Chemistry, 2002. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2931.

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<p>[<sup>11</sup>C]Carbon monoxide in low concentrations has been used in palladium- or seleniummediated carbonylation reactions such as the synthesis of <sup>11</sup>C-imides, hydrazides, amides, carboxylic acids, esters, carbothioates, ketones and carbamoyl compounds.</p><p>In these reactions aryl iodides have been used in most cases. However, less reactive aryl triflate, chloride and bromides were activated using tetrabutylammonium iodide.</p><p>The reactivities of nucleophiles may have influence on the radiochemical yield of the <sup>11</sup>Clabelled compounds. Carboxyamination of aryl ha
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Chung, Ching-Hui, and 鍾景揮. "(A) Synthesis of Aryl Hydrazide via Sonochemical Barbier-type Reaction and (B) Microwave Assisted Synthesis of Benzothiazole by Reaction of 2-Aminothiophenol with Aldehyde and Carboxylic Acid." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/52799365776440710530.

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碩士<br>淡江大學<br>化學學系碩士班<br>95<br>Aryl hydrazides are important precursors for synthesis of a variety of heterocycles such as indoles, pyrazoles, β-lactams, quinazolines and others, they are well known to be biologically active. In addition, aryl hydrazides can be transformed to aryl hydrazines and aryl amines, which can be further applied to synthesize heterocyclic compounds. Herein, our laboratory wish to report a novel synthetic method for preparation of aryl hydrazide from arylbromide, magnesium powder, 1,2-dibromoethane and diethyl azodicarboxylate via sonochemical Barbier-type reaction. In
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Book chapters on the topic "Hydrazine carboxylic acid"

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Pardasani, R. T., and P. Pardasani. "Molar magnetic moment of iron(III) mixed ligand complex with nicotinic acid [1-(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4yl)-methylidine]hydrazide and 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 2. Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62466-1_81.

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Pardasani, R. T., and P. Pardasani. "Molar magnetic moment of iron(III) mixed ligand complex with nicotinic acid [1-(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4yl)-acylidine]hydrazide and 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 2. Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62466-1_83.

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Pardasani, R. T., and P. Pardasani. "Molar magnetic moment of iron(III) mixed ligand complex with nicotinic acid [1-(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4yl)-butylidine]hydrazide and 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 2. Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62466-1_84.

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Pardasani, R. T., and P. Pardasani. "Molar magnetic moment of iron(III) mixed ligand complex with nicotinic acid [1-(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4yl)-2-phenylethylidine]hydrazide and 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 2. Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62466-1_85.

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Pardasani, R. T., and P. Pardasani. "Molar magnetic moment of iron(III) mixed ligand complex with nicotinic acid [1-(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4yl)-methylidine]hydrazide and 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 2. Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62466-1_82.

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"Carboxylic Acid or Ester and Hydrazide or Hydrazine." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470187302.ch67.

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"Carboxylic Acid or Ester and Hydrazine Ochydroxylamine Derivative." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470187319.ch67.

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Mourad, A. K., and C. Czekelius. "Synthesis from Carboxylic Acid Hydrazides." In Three Carbon-Heteroatom Bonds: Acid Halides; Carboxylic Acids and Acid Salts. Georg Thieme Verlag KG, 2011. http://dx.doi.org/10.1055/sos-sd-120-00059.

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Mourad, A. K., and C. Czekelius. "Hydrolysis of Hydrazides." In Three Carbon-Heteroatom Bonds: Acid Halides; Carboxylic Acids and Acid Salts. Georg Thieme Verlag KG, 2011. http://dx.doi.org/10.1055/sos-sd-120-00039.

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Ostrowska, K., and A. Kolasa. "Synthesis from Carboxylic Acid Hydrazides." In Three Carbon-Heteroatom Bonds: Amides and Derivatives; Peptides; Lactams. Georg Thieme Verlag KG, 2005. http://dx.doi.org/10.1055/sos-sd-022-00616.

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Conference papers on the topic "Hydrazine carboxylic acid"

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Tokareva, M. A., K. L. Obydennov, P. A. Slepukhin, O. A. Vysokova, and T. V. Glukhareva. "Reaction of sodium 4-acetyl-1-phenyl-1H-1,2,3-triazol-5-olate with 1,2,3-thiadiazole-4-carboxylic acid hydrazide." In PROCEEDINGS OF THE 3RD INTERNATIONAL CONFERENCE ON AUTOMOTIVE INNOVATION GREEN ENERGY VEHICLE: AIGEV 2018. Author(s), 2019. http://dx.doi.org/10.1063/1.5087392.

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