Relevant bibliographies by topics / Hydrazone derivatives

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Hydrazone derivatives'

Author: Grafiati
Published: 5 June 2025
Last updated: 15 July 2025

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Journal articles on the topic "Hydrazone derivatives"

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Ekram Abdullah Basheer, Kalid Matny Al-jaanaby, and Feras Shauki Al-joboury. "Synthesis a Number of Heterocyclic Compounds Derived From Levofloxacin." Tikrit Journal of Pure Science 20, no. 5 (2023): 84–95. http://dx.doi.org/10.25130/tjps.v20i5.1244.

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In this paper, the preparation a number of heterocyclic compounds five membered rings like oxadiazole, imidazolidine, thiozolidine, tetrazole, azetidine 2-on. Hydrazide (1) was synthesized from the reaction of levofloxacin with hydrazine hydrate. Hydrazone compounds (2-9) were synthesized from the reaction (1) with a number of aldehydes, and 3-acetyl-1,3,4-oxadiazol (10-17) was prepared from the reaction of hydrazones (2-9) with acetic anhydride, 5-oxo-2-aryl imadazoldine derivative (18-25) were prepared from the reaction of hydrazone derivatives (2-9) with glycine, while the reaction of hydra
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Nora, Amer Hussien, Y. Hussien Hyffaa, and H. Abdulrahman Shaymaa. "Predictive biological activity of newly synthesized hydrazone compounds derived from indomethacin." Journal of Wildlife and Biodiversity 7, Special Issue (2023): 391–402. https://doi.org/10.5281/zenodo.10246323.

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New derivatives of hydrazone have been successfully created, specifically 2-(1-(Aryl)-5-methoxy-2-methyl-1H-indol-3-yl)-N'-(2-chlorobenzylidene) acetohydrazide. The transformation of Indomethacin ester into hydrazide was achieved through a reaction with hydrazine hydrate in absolute ethanol, followed by the reaction of the resulting hydrazide with aromatic aldehydes. The structures of these newly synthesized hydrazones were validated through IR, 1HNMR, and 13CNMR analyses. Each compound's energies were optimized by utilizing density functional theory (DFT) for theoretical calculations. By empl
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Agili, Fatimah. "Novel Hydrazide Hydrazone Derivatives as Antimicrobial Agents: Design, Synthesis, and Molecular Dynamics." Processes 12, no. 6 (2024): 1055. http://dx.doi.org/10.3390/pr12061055.

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Ester 2 was produced by reacting thiourea derivative 1 with ethyl 2-chloro-3-oxobutanoate in MeOH containing piperidine. Hydrazide 3 was produced by reacting the latter ester with hydrazine hydrate in EtOH at reflux. By reacting hydrazide 3 with aromatic/heterocyclic aldehydes, twelve derivatives of hydrazide hydrazone 5a–l were produced. Spectral measurements and elemental analysis verified the molecular structure. Compounds 2, 5a, 5c, 5d, and 5f had strong effects on all the pathogenic bacterial strains according to an evaluation of the antimicrobial qualities of the synthetic compounds. Wit
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Kaur, Aneet Kamal, Renu Bala, Poonam Kumari, Sumit Sood, and Karan Singh. "Microwave Assisted Vilsmeier-Haack Reaction on Substituted Cyclohexanone Hydrazones: Synthesis of Novel 4,5,6,7-Tetrahydroindazole Derivatives." Letters in Organic Chemistry 16, no. 3 (2019): 170–75. http://dx.doi.org/10.2174/1570178615666180917101637.

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Vilsmeier-Haack reaction is one of the most important chemical reactions used for formylation of electron-rich arens. Even though Vilsmeier-Haack reaction was studied on a wide variety of hydrazones of enolizable ketones, literature lacks the examples of the use of 4-substituted cyclohexanones as a substrate. The cyclization potential of hydrazones of cyclic keto compounds is still interested topic of investigation. In the present study, the reaction of various hydrazines with 4-substituted cyclohexanones was proceeded and the resulted hydrazones in crude form were treated with Vilsmeier- Haac
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Al-Shiekh, Mariam A., Hanady Y. Medrassi, Mohamed H. Elnagdi, and Ebtisam A. Hafez. "Substituted Hydrazonals as Building Blocks in Heterocyclic Synthesis: A New Route to Arylhydrazonocinnolines." Journal of Chemical Research 2007, no. 7 (2007): 432–36. http://dx.doi.org/10.3184/030823407x234617.

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2-heteroylhydrazonopropanals 2a–e and 3-oxo-2-arylhydrazonopropanals 2f–k were prepared via coupling of enaminones 1 with aromatic diazonium salts. Compounds 2a–c condensed with hydrazine hydrate to yield the corresponding hydrazones 3a–c which afford on cyclisation the cinnoline derivatives 6a–c, while condensation of 2g, j with hydrazine hydrate directly yielded the pyrazole derivatives 4g–j. Condensation of 2a–c, f, g with phenyl hydrazine gave the corresponding phenyl hydrazone derivatives 7a–c, f, g. Structures of 2a, h and 3a were assessed by single crystal X-ray analyses.
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Hishmat, O. H., S. S. Mabrouk, A. M. M. Nasef, N. M. A. Shayeb, and S. A. Ismail. "Derivatives of Khellinonequinone and their Aflatoxigenic Activity." Zeitschrift für Naturforschung B 43, no. 3 (1988): 343–46. http://dx.doi.org/10.1515/znb-1988-0318.

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Nitration of khellinone leads to the formation of a small amount of 3-nitrokhellinone and 5-acetyl-6-hydroxybenzofuran-4.7-dione (khellinonequinone) as a main product. The latter compound reacts with primary amines to give the corresponding imino compounds. Reaction of khellinone with o-phenylenediamine involves condensation followed by cyclisation. While on the other hand treating with phenyl hydrazines gives the phenyl hydrazone. The pyrazolobenzofuran derivative was obtained by the action of hydrazine hydrate on khellinonequinone. Finally the reaction with malononitrile leads to the formati
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Abdelmohsen, Shawkat A., and Talaat I. El Emary. "SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF NOVEL PYRAZOLO[3,4-b]PYRIDINES AND THEIR SPIRO-HETEROCYCLIC DERIVATIVES." JOURNAL OF ADVANCES IN CHEMISTRY 10, no. 7 (2014): 2901–15. http://dx.doi.org/10.24297/jac.v10i7.6802.

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The present work describes the synthesis of a novel series of heterocyclic moieties derived from 5-acetylpyrazolo[3,4-b]pyridine (1). The formation of chalcones (2a-d) was utilized to synthesize pyrazoline, isoxazoline and pyrimidine derivatives (3-10). Thiosemicarbazone and semicarbazone (11, 17) were utilized to synthesize other new triazolethiones, thiadiazole and selenadiazole derivatives (11-19). Some new spiro derivatives (22-25) were synthesized by the reaction of chalcone (21) of 1 and isatine with hydrazines, hydroxyl amines and thiourea. Also, The reaction of 1 with cyanoacetyl hydra
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Edrees, Mastoura M. "Synthesis of 4-hydrazinopyrazolo[3,4-d]pyrimidines and their Reactions with Carbonyl Compounds." Journal of Chemical Research 37, no. 1 (2013): 6–10. http://dx.doi.org/10.3184/174751912x13543818811749.

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Synthesis of a new 4-hydrazinopyrazolo[3,4- d]pyrimidine was achieved via heating (4,6-dithioxo-1 H-pyrazolo[3,4- d] pyrimidin-3-yl)acetonitrile with hydrazine hydrate. Reactions of the latter product with thiophene-2-carbaldehyde and ethyl hydrazonoacetoacetate analogues afforded the corresponding hydrazone and pyrazole derivatives, respectively. Similarly, condensation of 2-[6-(benzylsulfanyl)-4-hydrazino-1 H-pyrazolo[3,4- d]pyrimidin-3-yl]acetonitrile with thiophene-2-carbaldehyde and ethyl hydrazonoacetoacetate analogues gave the respective hydrazone and pyrazolone derivatives. Alkylation
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Prateeptongkum, Saisuree, Nongnaphat Duangdee, and Wiratchanee Mahavorasirikul. "Evaluation of Cytotoxicity and Apoptosis Induced by Coumarin Hydrazide-Hydrazone Derivatives in Human Hepatocellular Carcinoma Cell Line." Trends in Sciences 21, no. 7 (2024): 7628. http://dx.doi.org/10.48048/tis.2024.7628.

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Coumarin and aryl hydrazide-hydrazone have attracted our attention due to their vast biological properties. Previous studies suggested that coumarin-tethered aryl hydrazide-hydrazone showed potent activities against HepG2. In the present study, we investigated the cytotoxic potency of the coumarin derivatives 1 - 3 to compare with coumarin hydrazine-hydrazone hybrids 4 and 5 against hepatocellular carcinoma HepG2 and LH86 cell lines. Among the tested coumarins, hybrids 4 and 5 showed highly potent activity against HepG2 with IC50 values of 17.82 ± 2.79 and 7.87 ± 0.88 𝜇g/mL, respectively. The
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Sapkota, Kamal Raj, Shilpi Kumari, Zeba Alam, and Md Serajul Haque Faizi. "Synthesis, and Structural Characterization of (E)-1-(4-((2-(2,4-Dinitrophenyl) hydrazono) methyl)phenyl) piperidine: A Combined Spectroscopic and Computational Study." Bhairahawa Campus Journal 7, no. 1 (2024): 41–55. https://doi.org/10.3126/bhairahawacj.v7i1.79948.

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This study Hydrazine-based piperidine derivatives are widely recognized for their significant roles in pharmaceutical development and material science research. In this context, the present study aimed to synthesize a novel hydrazone derivative to explore its structural and electronic features. This study presents the synthesis and structural characterization of (E)-1-(4-((2-(2,4-Dinitrophenyl)hydrazono)methyl)phenyl)piperidine) (DHP). The compound was obtained through a condensation reaction between 4-(piperidin-1-yl) benzaldehyde and (2,4-dinitrophenyl) hydrazine, achieving an 88% yield. Its
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Dissertations / Theses on the topic "Hydrazone derivatives"

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Garland, Keira. "A Practical Approach to Semicarbazone and Hydrazone Derivatives via Imino-isocyanates." Thèse, Université d'Ottawa / University of Ottawa, 2014. http://hdl.handle.net/10393/30725.

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Isocyanates have a broad spectrum of uses and they are used in the production of many products including polyurethane polymers, coatings, adhesives, paints and foams. While isocyanates are widely studied and well represented in the literature, nitrogen substituted isocyanates are quite rare. Amino and imino-isocyanates are examples of nitrogen substituted isocyanates. Previous work within the group studied the reactivity of these intermediates in the alkene aminocarbonylation reaction, and used hydrazones and hydrazides as precursors of nitrogen substituted isocyanates. From there, a secon
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Yazici, Ceyda. "Synthesis Of 4-iodopyrazole Derivatives." Master's thesis, METU, 2008. http://etd.lib.metu.edu.tr/upload/3/12609750/index.pdf.

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Pyrazoles have been studied for over a century as an important class of heterocyclic compounds and continue to attract considerable interest due to the broad range of biological activities they possess. The electrophilic cyclization of the acetylenic hydrazones initiated by molecular iodine could provide new ways of synthesizing biologically active 4-iodopyrazole derivatives, which are important precursors for the synthesis of highly substituted pyrazole derivatives. For this reason, we investigated the synthesis of 4-iodopyrazole derivatives, such as 1-aryl- 5-alkyl/aryl-4-iodopyrazoles, star
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Hauke, Tobias [Verfasser], and Klaus T. [Akademischer Betreuer] Wanner. "Exploring 5-substituted nipecotic acid derivatives in the search for novel GABA uptake inhibitors by means of MS based screening of pseudostatic combinatorial hydrazone libraries / Tobias Hauke ; Betreuer: Klaus T. Wanner." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2018. http://d-nb.info/1178323943/34.

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Clavette, Christian. "Synthesis of Beta-Aminocarbonyl Compounds and Hydrazine Derivatives Using Amino- and Imino-Isocyanates." Thesis, Université d'Ottawa / University of Ottawa, 2015. http://hdl.handle.net/10393/32004.

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Over the past recent years, β-aminocarbonyls have been of great interest to medicinal chemists. As a practical method to obtain these moieties, alkene aminocarbonylation, accounting for the formation of a C-N and a C-C bond, has been the subject of limited research efforts (very specific intramolecular metal-catalyzed variants have been reported). Direct aminocarbonylation of alkenes constitutes a challenging and an important potential innovation in the synthesis of β-aminocarbonyls such as β-amino acids. The research efforts described in the present thesis have been primarily directed towards
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Jia, Shuanglong. "Multicomponent Reactions toward Heterocycles and Tsuji-Trost Reaction of Allylic Nitro Derivatives." Thesis, Université Paris-Saclay (ComUE), 2018. http://www.theses.fr/2018SACLY012/document.

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Les réactions multicomposantes jouent un rôle important en chimie organique. Ce sont des réactions qui mettent en jeu au moins trois réactifs de départ et qui permettent d’obtenir des produits considérés comme des éléments intéressants pour la synthèse de molécules complexes ou de composés bioactifs. Grâce à leur versatilité, ces réactions sont considérées comme des outils précieux pour la préparation de bibliothèques de composés organiques dans le domaine de la recherche pharmaceutique et de la synthèse de produits naturels.La réaction de Passerini, combinée à une addition de Michael et à une
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Mingle, David. "Synthesis, Characterization and Biological Evaluation of Novel (S,E)-11-[2-(Arylmethylene) Hydrazono] Pyrrolo [2,1-c] [1,4] Benzodiazepine Derivatives." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/etd/3596.

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Pyrrolo [2,1-c] [1,4] benzodiazepine (PBD) is a class of natural products obtained from various actinomycetes which have both anti-tumor and antibiotic activities and can bind to specific sequences of DNA. PBD-dilactam was initially produced using isatoic anhydride and (L)-proline which was then converted to the PBD-thiolactam using Lawesson's reagent. Reaction of thiolactam with hydrazine in ethanol afforded PBD-11-hydrazinyl. Condensation of 11-hydrazinyl PBD with aldehydes possessing various substitutions was performed to obtain (S,E)-11-[2-(arylmethylene) hydrazono] pyrrolo [2,1-c] [1,4] b
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Mingle, David, and Abbas G. Dr Shilabin. "Synthesis, Characterization and Biological Evaluation of novel (S, E)-11-[2-(arylmethylene)hydrazono] pyrrolo [2,1-c] [1,4] benzodiazepine derivatives." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/asrf/2019/schedule/212.

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Pyrrolo [2,1-c] [1,4] benzodiazepine (PBD) is a class of natural products obtained from various actinomycetes which have both anti-tumor and antibiotic activities. They can bind to specific sequences of DNA that can trigger a biological response which is of pharmacological interest. PBD can also prevent cell division leading to death of the bacteria. This research focuses on the synthesis of novel 11-hydrazinyl PBD derivatives using a multi-step synthesis. PBD-dilactam was initially produced using isatoic anhydride and (L)-proline which was then converted to the PBD-thiolactam using Lawesson's
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Jia, Shuanglong. "Multicomponent Reactions toward Heterocycles and Tsuji-Trost Reaction of Allylic Nitro Derivatives." Electronic Thesis or Diss., Université Paris-Saclay (ComUE), 2018. http://www.theses.fr/2018SACLY012.

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Les réactions multicomposantes jouent un rôle important en chimie organique. Ce sont des réactions qui mettent en jeu au moins trois réactifs de départ et qui permettent d’obtenir des produits considérés comme des éléments intéressants pour la synthèse de molécules complexes ou de composés bioactifs. Grâce à leur versatilité, ces réactions sont considérées comme des outils précieux pour la préparation de bibliothèques de composés organiques dans le domaine de la recherche pharmaceutique et de la synthèse de produits naturels.La réaction de Passerini, combinée à une addition de Michael et à une
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Gormen, Meral. "Synthesis Of Ferrocenyl Substituted Pyrazoles." Master's thesis, METU, 2005. http://etd.lib.metu.edu.tr/upload/3/12606358/index.pdf.

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Pyrazoles have been studied for over a century as an important class of heterocyclic compounds and continue to attract considerable interest due to the broad range of biological activities they possess. The incorporation of the essential structural features of pyrazoles with a ferrocene moiety could provide new derivatives with unexpected and/or enhanced biological activities since several ferrocene derivatives have already been shown to be active against a number of tumors. For this reason, we investigated the synthesis of ferrocenyl-substituted pyrazoles, such as 1-alkyl/aryl-5-ferrocenylpyr
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Aumand, Livia M. "A Studies towards the formation of asymmetric quaternary centres via radical allylation B Applications of chiral hydrazide organocatalysts to Diels-Alder, hydride reduction, and alpha-chlorination reactions C Studies directed towards the synthesis of potential HIV-1 reverse transcriptase inhibitors: 9-Alkylaryl TIBO derivatives." Thesis, University of Ottawa (Canada), 2005. http://hdl.handle.net/10393/26843.

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In part A, the attempts at synthesizing quaternary centres via radical reactions are described. Using tartrate acetals as chiral auxiliaries, tertiary bromides were submitted to radical allylation conditions in an effort to form 1,3-dicarbonyl compounds 27 possessing an asymmetric quaternary centre at C2.* Part B describes the synthesis of chiral hydrazide 129 and its ability to catalyze the Diels-Alder reaction is examined. The application of chiral hydrazides 131 to the organocatalytic hydride reduction of alpha,beta-unsaturated aldehydes and the alpha-chlorination of aldehydes is also recou
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Books on the topic "Hydrazone derivatives"

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Schmidt, Eckart W. Hydrazine and its derivatives: Preparation, properties, applications. 2nd ed. Wiley-Interscience, 2001.

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Patil, K. C., and Tanu Mimani Rattan, eds. Inorganic Hydrazine Derivatives. John Wiley & Sons, Ltd, 2014. http://dx.doi.org/10.1002/9781118693599.

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United States. National Aeronautics and Space Administration, ed. Catalysts for the decomposition of hydrazine and its derivatives, and a method for its production. National Aeronautics and Space Administration, 1986.

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Patil, K. C., and Tanu Mimani Rattan. Inorganic Hydrazine Derivatives: Synthesis, Properties and Applications. Wiley & Sons, Incorporated, John, 2014.

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Patil, K. C., and Tanu Mimani Rattan. Inorganic Hydrazine Derivatives: Synthesis, Properties and Applications. Wiley & Sons, Incorporated, John, 2014.

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Inorganic Hydrazine Derivatives: Synthesis, Properties and Applications. Wiley, 2014.

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Patil, K. C., and Tanu Mimani Rattan. Inorganic Hydrazine Derivatives: Synthesis, Properties and Applications. Wiley & Sons, Limited, John, 2014.

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Patil, K. C., and Tanu Mimani Rattan. Inorganic Hydrazine Derivatives: Synthesis, Properties and Applications. Wiley & Sons, Incorporated, John, 2014.

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Catalysts for the decomposition of hydrazine, hydrazine derivatives and mixtures of both. National Aeronautics and Space Administration, 1986.

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Nielsen, Robert Peter 1937. Study of the Synthesis of Some Aluminum and Phosphorus Derivatives of Alkyl Hydrazines. Creative Media Partners, LLC, 2021.

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Book chapters on the topic "Hydrazone derivatives"

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Aruna, Singanahally T., and K. C. Patil. "Hydrazine Salts." In Inorganic Hydrazine Derivatives. John Wiley & Sons, Ltd, 2014. http://dx.doi.org/10.1002/9781118693599.ch02.

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Rattan, Tanu Mimani, and K. C. Patil. "Hydrazine and Its Inorganic Derivatives." In Inorganic Hydrazine Derivatives. John Wiley & Sons, Ltd, 2014. http://dx.doi.org/10.1002/9781118693599.ch01.

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Gajapathy, Dasaratharam, and Tanu Mimani Rattan. "Metal Hydrazines." In Inorganic Hydrazine Derivatives. John Wiley & Sons, Ltd, 2014. http://dx.doi.org/10.1002/9781118693599.ch03.

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Patil, K. C., and Tanu Mimani Rattan. "Metal Hydrazine Carboxylates." In Inorganic Hydrazine Derivatives. John Wiley & Sons, Ltd, 2014. http://dx.doi.org/10.1002/9781118693599.ch04.

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Govindrajan, Subbiah, and Singanahally T. Aruna. "Hydrazinium Metal Complexes." In Inorganic Hydrazine Derivatives. John Wiley & Sons, Ltd, 2014. http://dx.doi.org/10.1002/9781118693599.ch05.

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Patil, K. C., and Tanu Mimani Rattan. "Applications of Inorganic Hydrazine Derivatives." In Inorganic Hydrazine Derivatives. John Wiley & Sons, Ltd, 2014. http://dx.doi.org/10.1002/9781118693599.ch06.

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Powis, Garth. "Triazine and Hydrazine Derivatives." In Cancer Management in Man. Springer Netherlands, 1989. http://dx.doi.org/10.1007/978-94-009-1095-9_9.

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Savelyev, Yu. "Polyurethane Thermoplastic Elastomers Comprising Hydrazine Derivatives: Chemical Aspects." In Handbook of Condensation Thermoplastic Elastomers. Wiley-VCH Verlag GmbH & Co. KGaA, 2006. http://dx.doi.org/10.1002/3527606610.ch13.

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Pardasani, R. T., and P. Pardasani. "Molar magnetic moment of oxovanadium(IV) derivative with bis(hydrazone) derived from 1,1′-diacetylferrocene and isonicotinic acid hydrazide." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 1. Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62478-4_41.

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Pardasani, R. T., and P. Pardasani. "Molar magnetic moment of oxovanadium(IV) derivative with bis(hydrazone) derived from 1,1′-diacetylferrocene and benzoic acid hydrazide." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 1. Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62478-4_38.

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Conference papers on the topic "Hydrazone derivatives"

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Milenković, Dejan, Marko Antonijević, Edina Avdović, Dušica Simijonović, and Zoran Marković. "Design, in Silico Evaluation, and Toxicological Assessment of $N$-Protocatechoyl Hydrazone Derivatives as Potential EGFR Kinase Inhibitors." In 2024 IEEE 24th International Conference on Bioinformatics and Bioengineering (BIBE). IEEE, 2024. https://doi.org/10.1109/bibe63649.2024.10820446.

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Quraishi, M. A. "Lauric Hydrazide Derivatives: New Class of Volatile Corrosion Inhibitors." In CORROSION 2002. NACE International, 2002. https://doi.org/10.5006/c2002-02319.

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Abstract The protection of metals against corrosion by means of volatile compounds is the most progressive method of fighting metallic corrosion. These inhibitors are used to protect metallic articles and equipment during storage and transportation. In view of this we have synthesized six organic volatile corrosion inhibitors (VCIs) using Lauric hydrazide with various acids such as cinnamic acid, succinic acid, nitrobenzoic acid, phthalic acid and maleic acid and evaluated their inhibiting action on corrosion of mild steel, copper, brass, zinc and aluminium by weight loss and potentiodynamic p
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Branković, Jovica, Vesna Milovanović, and Vladimir P. Petrović. "CYCLOOXYGENASE-2 AS „IN SILICO“ TARGET OF PHENOLIC HYDRAZONE- TYPE DERIVATIVES." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2021. http://dx.doi.org/10.46793/iccbi21.324b.

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In the present work, a series of phenolic hydrazone analogs were investigated in silico for their potential inhibitory activity toward COX-2. These examinations were based on the capability of hydrazone-based compounds to interact with numerous enzymes, as well as on their versatile biological features and therapeutical applications. COX-2 was selected due to its involvement in the inflammation and carcinogenesis processes. Regarding this, COX-2 represents a valid target for the development of compounds that could block the formation of harmful inflammation mediators.
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Branković, Jovica, Zorica D. Petrović, and Vladimir P. Petrović. "Phenolic N-acyl hydrazone derivatives: In silico assessment of potential antibacterial activity against selected G+ and G- strains." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.491b.

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In this work, a series of phenolic N-acyl hydrazones was investigated in silico against six selected E. coli and S. aureus bacterial proteins. Generally, the obtained molecular docking results revealed significantly higher binding affinities of analogs a–n towards selected enzymes in comparison to standard compounds. In the case of E. coli proteins 1hnj, 1c14, and 6ntw, the lowest binding energies were calculated for derivatives l (-8.5 kcal/mol), d (-9.0 kcal/mol), and k (-8.2 kcal/mol), respectively. On the other hand, the highest binding affinity towards the S. aureus 3u2d, 1mwu, and 1jij e
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Branković, Jovica, Zorica D. Petrović, and Vladimir P. Petrović. "In silico antibiofilm potency of phenolic N-acyl hydrazones against selected bacterial strains." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.495b.

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In the present work, fourteen phenolic hydrazone derivatives were evaluated for their in silico inhibitory activity against selected P. aeruginosa and S. maltophilia proteins involved in drug resistance and biofilm formation. Molecular docking analysis revealed the highest binding affinity of analogs n (-8.4 kcal/mol) and h (-7.3 kcal/mol) towards P. aeruginosa 7m1m and 7m1l proteins, respectively. In the case of S. maltophilia, analog k (-8.4 kcal/mol) expressed the highest binding affinity to 6qw7, whereas for 6uaf, the lowest binding energy was calculated for derivative d (-8.1 kcal/mol). T
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Meier, U., M. S. Wong, F. Pan, C. Bosshard, and P. Gunter. "Five-Mernbered Heteroaromatic Hydrazone Derivatives for Second-Order Nonlinear Optics." In Proceedings of European Meeting on Lasers and Electro-Optics. IEEE, 1996. http://dx.doi.org/10.1109/cleoe.1996.562188.

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Meier, U., M. S. Wong, F. Pan, Ch Bosshard, P. Günter, and V. Gramlich. "Five-membered Heteroaromatic Hydrazone Derivatives for Second-Order Nonlinear Optics." In The European Conference on Lasers and Electro-Optics. Optica Publishing Group, 1996. http://dx.doi.org/10.1364/cleo_europe.1996.ctuk72.

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In the past decades, there have been extensive research efforts in developing new highly efficient organic materials with large second order susceptibilities because of their potential applications in optical signal processing and frequency conversion. Molecules possessing a large firstorder molecular hyperpolarizability ß are an essential prerequisite for achieving large macroscopic susceptibilities χ(2). The molecular nonlinearity of the classical, nonlinear optically active molecule, which usually contains an electron donor and an electron acceptor connected by a π-conjugated core, can be e
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Karimatu, Hamza, Idris Abdullahi Yunusa, Muhammad Aliyu Musa, Hamza Asmau Nasiru, Hamza Sa’adatu Auwal, and Abdullahi Maryam. "Synthesis and In Vitro Antibacterial Studies of Two New Hydrazone Derivatives." In International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2024. https://doi.org/10.3390/ecsoc-28-20138.

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Antonijević, Marko, Žiko Milanović, Dušica Simijonović, Zoran Marković, and Snežana Marković S. Zoran. "ANTIOXIDATIVE POTENCY AND RADICAL SCAVENGING ACTIVITY OF SELECTED COUMARIN-HYBRIDS." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac,, 2021. http://dx.doi.org/10.46793/iccbi21.458a.

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In previous studies, it was found that coumarins with hydrazide moiety show good antioxidative potential, while similar coumarins with hydrazone moiety are good anticancer agents. In this paper, the antioxidative potency and radical scavenging activity of two coumarin hydrazone derivatives were investigated. For this purpose, density functional theory method M062X with 6-311G++(d,p) basis set was implemented. It was found that investigated compounds exhibit good antioxidative potency, with very similar BDE values regardless of the position involved. On the other hand, PA values show that a pre
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Bosshard, Christian, Pan Feng, Man Shing Wong, Martin Bösch, Urs Meier, and Peter Günter. "Thiophene Based Hydrazones: a New Class of Nonlinear Optical Molecular Crystals." In Organic Thin Films for Photonic Applications. Optica Publishing Group, 1997. http://dx.doi.org/10.1364/otfa.1997.thd.2.

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Crystalline solids are often regarded as the best choice of material form for practical use as optical frequency converters because of the excellent long-term orientational stability and extremely high density of active components. Such materials can be combined with inexpensive diode lasers for optic parametric generation of a broad range of optical frequencies [1, 2]. We here report on our on-going efforts in the development of novel and highly efficient second-order nonlinear optical crystalline materials for frequency conversion, based on the hydrazone derivatives 5-(methylthio)-thiophenec
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