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Journal articles on the topic 'Hydroalcoholic product'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Moroșan, Elena, Ana Andreea Secăreanu, Adina Magdalena Musuc, et al. "Advances on the Antioxidant Activity of a Phytocomplex Product Containing Berry Extracts from Romanian Spontaneous Flora." Processes 10, no. 4 (2022): 646. http://dx.doi.org/10.3390/pr10040646.

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The present study aimed to evaluate the antioxidant properties of a phytocomplex product obtained using 10% hydroalcoholic extractive solutions, in equal proportions, from Ribes nigrum, Rubus idaeus, Rubus fruticosus and Fragaria moschata fresh fruits harvested from the spontaneous flora of Romania. These plant products were recognized for their rich antioxidant content. The phytochemical profile was assessed using HPLC chromatography and UV-Vis spectrometry. The obtained results highlighted the presence of complex bioactive compounds with antioxidant actions, namely anthocyanins, proanthocyan

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Moroșan, Elena, Magdalena Mititelu, Doina Drăgănescu, et al. "Investigation into the Antioxidant Activity of Standardized Plant Extracts with Pharmaceutical Potential." Applied Sciences 11, no. 18 (2021): 8685. http://dx.doi.org/10.3390/app11188685.

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Given the important role of antioxidants in the cellular degeneration process, as well as the increased interest in recent years related to the use of natural antioxidants in therapy, the present study aims to investigate the antioxidant activity of a new pharmaceutical product containing natural antioxidants extracted from plant raw materials. In a first step, the product conventionally named “CILTAG”, containing a mixture in equal proportions of 10% hydroalcoholic extractive solutions of dried plant raw materials from Medicaginis herba, Trifolii pratense flores, Ginkgo bilobae folium, Myrtil

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3

Buleandra, Mihaela, Zenovia Moldovan, Irinel Adriana Badea, et al. "Comparative Assessment of the Volatile Profile, Antioxidant Capacity and Cytotoxic Potential of Different Preparation of Millefolli Herba Samples." Revista de Chimie 71, no. 3 (2001): 69–78. http://dx.doi.org/10.37358/rc.20.3.7975.

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Millefolii herba is an available product on the Romanian market as mixture of stems, leaves and flowers of Achillea millefolium L. There were established its volatile compounds profile, total polyphenolic content (TPC), antioxidant capacity and effects on HCT 116 cell viability and programmed cell death. The infusion, hydroalcoholic extract and hydrodistillated essential oil were studied. A comparative analysis using static headspace (HS) and hydro-distillation (HD) GC/MS of the volatile components from Millefolii herba was realized: the essential oil contains chamazulene as the principal comp

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Valdiviezo Rogel, Carlos Jefferson, Glenda Marcela Sarmiento Tomalá, Pilar Asunción Soledispa Cañarte, Zoraida Burbano Gómez, and Francisca Patricia Jimenez Granizo. "Study of the normoglycaemic effect in experimental animals between aqueous extract and ethanolic extract of banana flower stalk (Musa acuminata Colla." Health Leadership and Quality of Life 2 (December 30, 2023): 209. https://doi.org/10.56294/hl2023209.

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The use of fruits and their derivatives in a population represents a daily practice that helps to solve problems not only of a nutritional nature but also of health. The present study has as its application the evaluation of the normoglycemic effect of extracts (aqueous and hydroalcoholic) of Sechium edule (Jacq.) SW. (chayote) in biomodels. ”To obtain the aqueous extracts, the fresh fruits were cleaned, the seeds removed, liquefied and filtered; for the 50:50 hydroalcoholic extract; it was added to the smoothie and macerated for 48 hours. Quality control parameters were determined (ashes, moi

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Quiñónez Mosquera, Susana Viviana, Ingrid Rafaela Rugel Rivera, Zoraida Burbano Gómez, and Glenda Sarmiento Tomala. "Evaluation Of The Normoglycemic Effect Of Extracts (Aqueous And Hydroalcoholic) Of Sechium Edule (Jacq.) Sw. (Chayote) In Biomodels." Health Leadership and Quality of Life 2 (December 31, 2023): 215. https://doi.org/10.56294/hl2023215.

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The use of fruits and their derivatives in a population represents a daily practice that helps to solve problems not only of a nutritional nature but also of health. The present study has as its application the evaluation of the normoglycemic effect of extracts (aqueous and hydroalcoholic) of Sechium edule (Jacq.) SW. (chayote) in biomodels. ”To obtain the aqueous extracts, the fresh fruits were cleaned, the seeds removed, liquefied and filtered; for the 50:50 hydroalcoholic extract; it was added to the smoothie and macerated for 48 hours. Quality control parameters were determined (ashes, moi

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Machado, Adriana Rodrigues, Maria Inês Rodrigues Machado, and Letícia Fleury Viana. "Use of biotechnology to produce alcoholic and acetic fermentation: A review." Research, Society and Development 12, no. 12 (2023): e102121223288. http://dx.doi.org/10.33448/rsd-v12i12.23288.

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Biotechnology enables numerous processes, such as fermentation, which uses desirable microorganisms to add value to commercial importance products. Alcoholic fermentation, a type of chemical reaction carried out by microorganisms (yeasts) in sugars, yields ethanol and carbon dioxide. Fermented acetic acid has been defined as the product obtained from the acetic fermentation of alcoholic liquid from fruit must, cereal, vegetable, honey, mixtures of vegetables, and hydroalcoholic mixtures. This review aimed to introduce alcoholic and acetic fermentation concepts and highlight the importance of s

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Viroli, Sérgio Luis Melo, Sérgio Guimarães Viroli, Nelson Pereira Carvalho, Delma Pereira da Silva Bernardi, and Rachel Gomes Coelho. "Production and characterization of acetic fermentation with different fruit peels." Research, Society and Development 10, no. 14 (2021): e84101421878. http://dx.doi.org/10.33448/rsd-v10i14.21878.

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Acetic fermentation or vinegar is the product obtained from fermented alcoholic wort, cereals or hydroalcoholic mixture with a minimum volatile acidity of 4g/100m.L-1. The present study produced, characterized and correlated the total dry extract with the density of the acetic fermented produced from the pineapple and apple peels. The fermentation process used pineapple and apple peel with culture medium, 10% hydroalcoholic solution, room temperature between 28 ± 2°C and irrigation 4 (four) times a day, without aeration for 12 days. Physico-chemical determinations of volatile acidity, density,

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Oliveira, Rafaela Dias, Carina Araújo, and Cristina Almeida-Aguiar. "In Vitro Antimicrobial Potential of Portuguese Propolis Extracts from Gerês against Pathogenic Microorganisms." Antibiotics 13, no. 7 (2024): 655. http://dx.doi.org/10.3390/antibiotics13070655.

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Antimicrobial resistance (AMR) is one of humanity’s main health problems today. Despite all the breakthroughs and research over the past few years, the number of microbial illnesses that are resistant to the available antibiotics is increasing at an alarming rate. In this article, we estimated the biomedical potential of Portuguese propolis harvested from the Gerês apiary over five years, evaluating the in vitro antimicrobial effect of five hydroalcoholic extracts prepared from five single propolis samples and of a hydroalcoholic extract obtained from the mixture of all samples. The antimicrob

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García-Rodríguez, Paula, Feifei Ma, Carmen del Río, et al. "Diet Supplementation with Polyphenol-Rich Salicornia ramosissima Extracts Protects against Tissue Damage in Experimental Models of Cerebral Ischemia." Nutrients 14, no. 23 (2022): 5077. http://dx.doi.org/10.3390/nu14235077.

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Strokes are the second most common cause of death worldwide and a leading cause of disability. Regular consumption of polyphenols has been shown to reduce the risk of suffering a cardiovascular event. For this reason, we have investigated the protective effect of Salicornia ramosissima, a seasonal halophyte that synthetizes high amounts of bioactive compounds, including polyphenols, in response to environmental stress. Aqueous, hydroalcoholic, and ethanolic extracts were prepared to investigate if dietary supplementation prior to ischemic challenge can prevent subsequent damage using two anima

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10

Polo, Ana, Thaís Uber, Gustavo Henrique Souza, et al. "Inhibitory Effects of Aqueous and Hydroalcoholic Extracts from Jatobá Coat (Hymenaea courbaril L.) on Pancreatic Amylase and Starch Absorption." Plants 14, no. 7 (2025): 1133. https://doi.org/10.3390/plants14071133.

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Jatobá (Hymenaea courbaril) is a native tree abundant in Brazil. The fruit coat is an industrial by-product of jatobá flour processing, typically discarded. Presently, within the circular bioeconomy concept, there are efforts underway that aim at finding economically viable applications for the bio-residues of jatobá. Within this context, the present work attempts to find possible applications for the jatobá coat in glycemic control through inhibition of -amylase activity. Aqueous and hydroethanolic extracts were used. In vitro experiments included detailed kinetic studies with an -amylase cat

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Danert, Fátima C., Catiana Zampini, Roxana Ordoñez, Luis Maldonado, Enrique Bedascarrasbure, and María Inés Isla. "Nutritional and Functional Properties of Aqueous and Hydroalcoholic Extracts from Argentinean Propolis." Natural Product Communications 9, no. 2 (2014): 1934578X1400900. http://dx.doi.org/10.1177/1934578x1400900209.

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Bee propolis is a natural product extensively used as an ingredient in functional foods in amounts that may confer health benefits. The aim of this study was to investigate the nutritional and functional properties (antioxidant activity) of aqueous and ethanolic extracts of propolis samples from Santiago del Estero province, northern Argentina. All propolis extracts contained macronutrients (glucose, fructose, sucrose and proteins), micronutrients (Na, K, Ca, P and Mg) and trace elements (Fe). Spectrophotometric, TLC and HPLC-DAD analyses showed the presence of several phenolic, flavonoid and

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TĂNASĂ ACREȚEI, Maria-Virginia, Ticuța NEGREANU-PÎRJOL, Carmen CHIFIRIUC, Dan Răzvan POPOVICIU, Larisa ANGHEL CIREAȘĂ, and Natalia ROȘOIU. "Preliminary Data Regarding Polyphenols, Carotenoids and Flavonoids Content Correlated with Antioxidant Activity of some Taraxacum Sp. Fluid Extracts." Annals of the Academy of Romanian Scientists Series on Biological Sciences 11, no. 1 (2022): 31–44. http://dx.doi.org/10.56082/annalsarscibio.2022.1.31.

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In the biomedical sciences field of recent years, phytotherapeutic products usage has intensified because they are a safe and sustainable alternative, with less environmentally aggressive molecules that are able to meet therapeutic needs. Mature vegetal product Taraxacum sp., also known as dandelion, has been used for hundreds of years as a traditional remedy for liver, kidney, lung, gastric diseases and even some cancers, due to its anti-inflammatory and antioxidant effects. The aim of this paper was to assess the contents of some bioactive principles and overall antioxidant potential of Tara

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Sultanova, Madina, Askhat Dalabayev, Aigerim Saduakas, Aida Nurysh, Nurtore Akzhanov, and Madina Yakiyayeva. "The potential of non-traditional walnut shells waste for the production of antioxidant reach extracts intended for the food industry." Potravinarstvo Slovak Journal of Food Sciences 17 (May 9, 2023): 391–404. http://dx.doi.org/10.5219/1862.

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Phenolic compounds extracted from walnut shells are potentially good natural sources of antioxidants for the food industry and have numerous health benefits. Walnuts have more antioxidant capacity than any other nut because the shell is primarily composed of lignin, a strong source of phenols. Studies demonstrated that lignin characterizes the shell strength level and is a source of antioxidants due to its chemical composition. In the current study, an extract obtained by extraction with a hydroalcoholic solvent of various concentrations from a walnut shell was investigated. The results of thi

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Upadhyay, Sukriti, and Bhaskar Kumar. "A brief study on standardization and evaluation of ayurvedic preparations of Ushirasava." YMER Digital 21, no. 07 (2022): 1097–103. http://dx.doi.org/10.37896/ymer21.07/90.

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Ushirasava is the polyherbal hydroalcoholic product prepared from about 27 ingredients. It is a liquid preparation popularly used for bleeding disorders, skin diseases, diabetes and many more. Due to the cooling properties of Ushirasava, it is widely used in the diseases where excessive heat occurs in the body. This study aimed to standardize and evaluate some marketed formulations of Ushirasava with special reference to its physicochemical properties. The organoleptic and physicochemical properties of Ushirasava were standardized with reference to the protocol of testing Ayurvedic, Siddha and

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15

Benvenutti, Larissa, Roberta Nunes, Ivonilce Venturi, et al. "Anti-Inflammatory and Healing Activity of the Hydroalcoholic Fruit Extract of Solanum diploconos (Mart.) Bohs." Journal of Immunology Research 2021 (July 19, 2021): 1–13. http://dx.doi.org/10.1155/2021/9957451.

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Background. Solanum diploconos (Mart.) Bohs is a native Brazilian plant belonging to the Solanaceae family, popularly known as “tomatinho do mato” and poorly investigated. Herein, we presented for the first time evidence for the anti-inflammatory and wound healing activities of S. diploconos fruit hydroalcoholic extract. Material and Methods. In vitro fMLP-induced chemotaxis, LPS-induced inflammatory mediator levels (cytokines by ELISA and NO release by Griess reaction), and adhesion molecule expression (CD62L, CD49d, and CD18, by flow-cytometry) were assessed in neutrophils treated with diffe

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16

Spizzirri, Umile Gianfranco, Avazbek Abduvakhidov, Paolino Caputo, et al. "Kefir Enriched with Carob (Ceratonia siliqua L.) Leaves Extract as a New Ingredient during a Gluten-Free Bread-Making Process." Fermentation 8, no. 7 (2022): 305. http://dx.doi.org/10.3390/fermentation8070305.

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This work is focused on the preparation of an innovative gluten-free (GF) bread with remarkable softness and antioxidant features over time. To overcome the technological inconveniences related to the removal of gluten from bread, the kefir beverage fortified with antioxidant vegetable extracts is employed as a functional ingredient in the bread-making process. In this context, carob (Ceratonia siliqua L.) leaves represent an outstanding source of active molecules and are proposed to enrich milk-based beverages. Different extraction strategies were evaluated, and the process was improved to se

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S, Kalaivanan, and Srinivasan R. "Investigation of Phytochemical Composition and In-vitro Antioxidant Activity of Canthium parviflorum Leaf Extract." INTERNATIONAL JOURNAL OF PHARMACEUTICAL QUALITY ASSURANCE 15, no. 02 (2024): 666–70. http://dx.doi.org/10.25258/ijpqa.15.2.18.

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This study provides a thorough investigation of Canthium parviflorum leaves, integrating macroscopical, phytochemical, and in-vitro antioxidant analyses to unveil the plant’s therapeutic potential. The preliminary phytochemical analysis identifies a diverse array of bioactive compounds in C. parviflorum, encompassing alkaloids, terpenoids, phenols, flavonoids, tannins, glycosides, saponins, gum, and mucilage, known for their potential pharmacological activities. Physico-chemical parameters characterize the leaves, with a moisture content of 6.9% w/w indicating water content and ash values prov

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Cannas, Michela, Paola Conte, Antonio Piga, and Alessandra Del Caro. "Artichoke By-Product Extracts as a Viable Alternative for Shelf-Life Extension of Breadsticks." Foods 13, no. 16 (2024): 2639. http://dx.doi.org/10.3390/foods13162639.

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The upcycling of agricultural by-products and the extension of the shelf-life of staple foods represent crucial strategies for mitigating the consequences of food losses and enhancing the competitiveness of the agri-food industry, thus facilitating the attainment of higher financial revenues. This is particularly relevant for global artichoke cultivation, where 60–80% of its biomass is discarded annually. The present study investigated the potential of using non-stabilized polyphenol-rich extracts from the main artichoke by-products (bracts, leaves, and stems) to fortify and extend the shelf-l

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Barrientos, Mariana Alejandra Echalar, Juliana Peralta, Fabrício Luiz Tulini, et al. "Encapsulation of Chasteberry (Vitex agnus castus L.) Extract by Spray-Drying Followed by Spray-Chilling for Its Application in Dark Chocolate." Foods 13, no. 23 (2024): 3742. http://dx.doi.org/10.3390/foods13233742.

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Chasteberry extract offers considerable phytotherapeutic benefits, particularly in alleviating premenstrual syndrome (PMS) symptoms. However, its hydroalcoholic nature leads to a bitter taste and a burning sensation, presenting challenges for direct consumption or incorporation into new food products. This study aimed to address these issues by encapsulating concentrated chasteberry extract using spray-drying with Arabic gum, followed by spray-chilling with vegetable fat as carriers. The encapsulated particles were characterized by their morphology, size, and stability, with a specific focus o

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Maria Rocha e Silva Crespo, Juliana, Pamella Teixeira Lazzari, Rondinelli De Carvalho Ladeira, Marcelo Soares Crespo, and Sthepano Picanço Damian Resende. "PHYTOCHEMICAL STUDY OF BACCHARIS DRACUNCULIFOLIA (ASTERACEAE) WITH ANTIOXIDANT POTENTIAL FOR THE DEVELOPMENT OF PHYTOCOSMETICS FORMULATION." Health and Society 4, no. 01 (2024): 184–99. http://dx.doi.org/10.51249/hs.v4i01.1860.

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This study addressed the development of a phytocosmetic with antioxidant appeal, using the extract of Baccharis dracunculifolia (Asteraceae) with therapeutic potential as the active ingredient. The research involved the phytochemical analysis of the plant, highlighting the presence of compounds such as alkaloids, flavonoids, and tannins, indicative of antioxidant activity. Baccharis dracunculifolia, known as “alecrim do campo,” was collected in the rural area of Muriaé, MG, and subjected to different extraction techniques to obtain hydroalcoholic and glycolic extracts. Phytochemical screening

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Vieira, José Sebastião Cidreira, Neemias da Silva Nascimento, Hugo da Costa Reis, et al. "Handcrafted soaps made from medicinal plants extracts sourced from Zé Doca, Maranhão, Brazil." Caderno Pedagógico 22, no. 6 (2025): e15425. https://doi.org/10.54033/cadpedv22n6-081.

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In the Alto Turi region of Maranhão, the production of natural handcrafted soaps is an economically viable alternative regarding the use of medicinal herbs and plants. Obtaining soaps requires high-quality fatty raw materials and a strong base, as during the saponification reaction, these materials must be completely consumed to generate a suitable final product with excellent quality. According to the Brazilian Health Regulatory Agency (ANVISA), an ideal soap for human consumption should contain free alkalinity (FA) in the range of 0.1-0.5% and a pH close to 10.4-11.5. During the manufacturin

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Roxo, Mariana, Herbenya Peixoto, Pille Wetterauer, Emerson Lima, and Michael Wink. "Piquiá Shells (Caryocar villosum): A Fruit by-Product with Antioxidant and Antiaging Properties in Caenorhabditis elegans." Oxidative Medicine and Cellular Longevity 2020 (August 25, 2020): 1–19. http://dx.doi.org/10.1155/2020/7590707.

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In a context of rising demand for sustainable antiaging interventions, fruit processing by-products are a promising source of bioactive compounds for the production of antiaging dietary supplements. Piquiá (Caryocar villosum) is a native Amazonian fruit consisting of 65% nonedible shells. In the present study, the phytochemical profile of a hydroalcoholic extract of piquiá shells (CV) was characterized by LC-MS/MS analysis. Its antioxidant and antiaging activities were investigated using the nematode Caenorhabditis elegans as an in vivo model. CV is mainly composed by hydrolysable tannins and

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Groşan, Alexandra, Camil-Eugen Vari, Ruxandra Ştefănescu, et al. "Antibacterial and antitumor activity of the species Prunella vulgaris L." Revista Romana de Medicina de Laborator 28, no. 4 (2020): 405–17. http://dx.doi.org/10.2478/rrlm-2020-0031.

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Abstract Background: Prunella vulgaris L., known as self-healing herb, is a widely spread species in the spontaneous flora with beneficial effects on human health, a fact proven in particular by Asian researchers. The aim of this study was to evaluate the antitumor activity and the antibacterial effect on different bacterial strains, including multidrug-resistant ones, depending on the type of solvent used (aqueous, hydroalcoholic), the plant product taken into consideration (spike inflorescence, leaf), its quantity and the concentration of active principles. Material and method: For screening

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Sariñana-Aldaco, Oscar, Adalberto Benavides-Mendoza, Armando Robledo-Olivo, and Susana González-Morales. "The Biostimulant Effect of Hydroalcoholic Extracts of Sargassum spp. in Tomato Seedlings under Salt Stress." Plants 11, no. 22 (2022): 3180. http://dx.doi.org/10.3390/plants11223180.

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Currently, the use of biostimulants in agriculture is a tool for mitigating certain environmental stresses. Brown algae extracts have become one of the most important categories of biostimulants in agriculture, and are derived from the different uses and positive results obtained under optimal and stressful conditions. This study aimed to examine the efficacy of a foliar application of a hydroalcoholic extract of Sargassum spp. and two controls (a commercial product based on Ascophyllum nodosum and distilled water) with regard to growth, the antioxidant system, and the expression of defense ge

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TĂNASĂ ACREȚEI, Maria-Virginia, Ticuța NEGREANU-PÎRJOL, Carmen CHIFIRIUC, et al. ""Carotenoids Content in Plant Organs of Taraxacum Officinale (L.) Species from Two Romanian Regions"." Annals of the Academy of Romanian Scientists Series on Biological Sciences 12, no. 1 (2023): 71–81. http://dx.doi.org/10.56082/annalsarscibio.2023.1.71.

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"Carotenoids are pigments that occur naturally in bacteria, algae, fungi and plants and give them their orange or red colour. The most important carotenoids that have beneficial effects on human health are beta-carotene, lutein, astaxanthin, lycopene and zeaxanthin. The main advantage of carotenoids lies in their antioxidant potential, the role of protecting the body's cells from damage by unstable oxygen molecules. The present paper presents the comparative content of carotenoid-type bioactive compounds present in the hydroalcoholic extracts obtained from different plant organs (roots, leaves

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da Cunha Rodrigues, Larissa, Renata Barbosa Bodini, Fernando de Lima Caneppele, et al. "Pressurized Liquid Extraction (PLE) in an Intermittent Process as an Alternative for Obtaining Passion Fruit (Passiflora edulis) Leaf Hydroalcoholic Extract (Tincture)." Processes 11, no. 8 (2023): 2308. http://dx.doi.org/10.3390/pr11082308.

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Tinctures are medicinal plant extracts obtained by extraction with a hydroalcoholic solution (70%) by percolation (PER). This process takes about 26 h to prepare, in addition to using a large amount of solvent. In our research, passion fruit leaf tinctures were obtained using extract with the same pressurized hydroalcoholic solution as in an intermittent process. The objective was to demonstrate that this emerging technology can be economical and profitable. An optimization using Central Composite Rotatable Design (CCRD) was performed to evaluate the influence of process variables on the yield

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Y. Muttalib, Lana, and Alaadin M. Naqishbandi. "Antibacterial and Phytochemical Study of Iraqi Salvia officinalis Leave Extracts." Iraqi Journal of Pharmaceutical Sciences ( P-ISSN 1683 - 3597 E-ISSN 2521 - 3512) 21, no. 1 (2017): 93–97. http://dx.doi.org/10.31351/vol21iss1pp93-97.

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Sage (Salvia officinalis), belong to Labiatae family is indigenous to Iraq and other Mediterranean areas but now cultivated world- wide, principally for its use as culinary herb. In the present study preliminary screening for the important phytochemical natural product groups indicated the presence of flavonoid, saponin, hyrolysable and condensed tannin groups. The antibacterial activity of two concentrations 10 mg/ml and 100 mg/ml of chloroform and hydroalcoholic extracts from Salvia officinalis leaves was evaluated against four strains of gram negative bacteria (Escherichia coli, Pseudomonas

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Silva, Maria Suênia P., Deysiane O. Brandão, Thiago P. Chaves, et al. "Study Bioprospecting of Medicinal Plant Extracts of the Semiarid Northeast: Contribution to the Control of Oral Microorganisms." Evidence-Based Complementary and Alternative Medicine 2012 (2012): 1–6. http://dx.doi.org/10.1155/2012/681207.

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Dental pathologies can be caused by plaque-forming bacteria and yeast, which reside in the oral cavity. The bacteria growing in dental plaque, a naturally occurring biofilm, display increased resistance to antimicrobial agents. The objective was the evaluation of a preclinical assay of medicinal plants of the semiarid region from the northeast against oral pathogenic microorganism, aiming at bioprospecting a new product. The selection of plant material for this study was based on the ethnobotanical data on the traditional use of plants from the semiarid region. The thirty extracts were subject

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Sousa, Marcus Vinicius Carvalho de, Simone Acrani, and Karina Ferrazzoli Devienne Vicentine. "Antioxidant effect and phytochemical characterization of commercial phytotherapic and extracts obtained from red yeast rice." Concilium 24, no. 4 (2024): 380–93. http://dx.doi.org/10.53660/clm-2967-24d60.

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The red yeast rice has been used in therapy for hypercholesterolemia, however data on the phytochemical constitution and other biological properties of this product are scarce in the scientific literature. This objective work evaluates the antioxidant capacity and phytochemical constitution of a commercial phytotherapic and extracts obtained from red yeast rice. The results demonstrated that both the commercial phytotherapic (EMFC), and aqueous (EA), hydroalcoholic (EHA) and ethanolic (EE) exctract presented antioxidant effects, and showed a direct relationship with the phenolic content. Among

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Vieira, José Sebastião Cidreira, João Darlon Alves do Ano, Agustinho Rodrigues Pereira, et al. "Advanced formulation of intimate lubricating gel for relief of atrophic vaginitis in menopausal women." Caderno Pedagógico 22, no. 6 (2025): e15424. https://doi.org/10.54033/cadpedv22n6-080.

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Climacteric is a period in which several symptoms are triggered in women's health, bringing about profound changes of both positive and negative nature. Among these, the onset of menopause, characterized by the last menstruation, stands out, which results in the reduction of the woman's reproductive capacity. In this sense, intimate lubricating gels were manufactured to combat atrophic vaginitis in climacteric women. This research aimed to prepare and develop intimate lubricating gels based on water and hydroalcoholic extract of medicinal plants (phytoestrogens) aiming at revitalizing the vagi

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D’Eusanio, Veronica, Andrea Marchetti, Mirco Rivi, et al. "Mineral Composition Analysis of Red Horse-Chestnut (Aesculus × Carnea) Seeds and Hydroalcoholic Crude Extract Using ICP OES." Molecules 30, no. 4 (2025): 819. https://doi.org/10.3390/molecules30040819.

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This study presents findings on the metal and metalloid composition of red horse-chestnut (Aesculus × carnea, AXC) seeds, determined by the ICP OES technique. Samples were collected from five AXC plants located in Modena (Italy) over four consecutive years (2016–2019). The seeds underwent proximate analysis, which included measurements of moisture content, proteins, lipids, carbohydrates, ash, and elemental composition. The analysis revealed consistent values for these parameters throughout the study period. The metal content of the AXC seeds can be categorized into two groups: (i) major compo

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Mengoni, Beatrice, Federica Armeli, Emily Schifano, et al. "In Vitro and In Vivo Antioxidant and Immune Stimulation Activity of Wheat Product Extracts." Nutrients 17, no. 2 (2025): 302. https://doi.org/10.3390/nu17020302.

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Background/Objectives: Inflammation and oxidative stress are the main pathogenetic pathways involved in the development of several chronic degenerative diseases. Our study is aimed at assessing the antioxidant and anti-inflammatory activity of hydroalcoholic extracts obtained from wheat and its derivatives. Methods: The content of total phenolic and total flavonoid compounds and antioxidant activity were carried out by ABTS and DPPH assays. The ability of wheat extracts to promote microglia polarization towards an anti-inflammatory phenotype was evaluated analyzing the increased expression of

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Santos, Carolina, Luciano Campestrini, Douglas Vieira, et al. "Chemical Characterization of Opuntia ficus-indica (L.) Mill. Hydroalcoholic Extract and Its Efficiency against Gastrointestinal Nematodes of Sheep." Veterinary Sciences 5, no. 3 (2018): 80. http://dx.doi.org/10.3390/vetsci5030080.

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Opuntia ficus-indica (L.) Mill. is a xerophylous plant that originated in tropical and subtropical America. This plant is popularly known in Brazil as “palma forrageira” (cactus pear) and plays a fundamental role in animal nutrition, mainly in the Northeastern semi-arid region of the country. The plant has several uses since it presents bioactive compounds that confer biological and pharmacological properties. In this context, the cactus pear can also be considered a potential product to combat parasite infections. The objective of this study was to chemically characterize the O. ficus-indica

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Martins, Valter F. R., Tânia B. Ribeiro, Ana I. Lopes, Manuela E. Pintado, Rui M. S. C. Morais, and Alcina M. M. B. Morais. "Comparison among Different Green Extraction Methods of Polyphenolic Compounds from Exhausted Olive Oil Pomace and the Bioactivity of the Extracts." Molecules 29, no. 9 (2024): 1935. http://dx.doi.org/10.3390/molecules29091935.

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The use of by-products as a source of bioactive compounds with economic added value is one of the objectives of a circular economy. The olive oil industry is a source of olive pomace as a by-product. The olive pomace used in the present study was the exhausted olive pomace, which is the by-product generated from the air drying and subsequent hexane extraction of residual oil from the olive pomace. The objective was to extract bioactive compounds remaining in this by-product. Various types of green extraction were used in the present study: solvent extraction (water and hydroalcoholic); ultraso

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Marchetti, Marcello, Alessandro Perini, Michela Zanella, Federico Benetti, and Daniela Donelli. "Study on the Fate of the Carbopol® Polymer in the Use of Hand Sanitizer Gels: An Experimental Model to Monitor Its Physical State from Product Manufacturing up to the Final Hand Rinse." Microplastics 3, no. 3 (2024): 390–404. http://dx.doi.org/10.3390/microplastics3030024.

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Carbopol® is a typical jelly agent belonging to the family of cross-linked polyacrylic acid copolymers. It is largely used in antibacterial gels due to its self-wetting properties. In its pristine physical form, Carbopol® falls under the definition of microplastics, though significant changes could occur once added to hydroalcoholic solvents of the liquid formulations. To date, no life-cycle data regarding the physical state are available for this substance or for other similar polymers of the same chemical class. The aim of the present study was the investigation of the fate of Carbopol®-deri

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Pérez Gutíerrez, Carmen Laura, Alessandro Di Michele, Cinzia Pagano, et al. "Polymeric Patches Based on Chitosan/Green Clay Composites and Hazelnut Shell Extract as Bio-Sustainable Medication for Wounds." Pharmaceutics 15, no. 8 (2023): 2057. http://dx.doi.org/10.3390/pharmaceutics15082057.

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Hazelnut shells, the main waste deriving from hazelnut processing, represent an interesting source of active molecules useful in pharmaceutics, although they have not yet been examined in depth. A hydrosoluble extract (hazelnut shell extract, HSE) was prepared by the maceration method using a hydroalcoholic solution and used as the active ingredient of patches (prepared by casting method) consisting of composites of highly deacetylated chitosan and green clay. In vitro studies showed that the formulation containing HSE is able to stimulate keratinocyte growth, which is useful for healing purpo

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Schiavone, Maria Lucia, Roberta Barletta, Alfonso Trezza, et al. "Green Chemistry Within the Circular Bioeconomy to Harness Chestnut Burr Extract’s Synergistic Antimicrobial Activity Against Helicobacter pylori." Molecules 30, no. 2 (2025): 324. https://doi.org/10.3390/molecules30020324.

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Green chemistry principles are pivotal in driving sustainable and innovative solutions to global health challenges. This study explores a hydroalcoholic extract from Castanea sativa (chestnut) burrs, an underutilized natural resource, as a potent source of antimicrobial compounds against Helicobacter pylori (H. pylori). The extract demonstrated significant bactericidal activity, synergizing effectively with clarithromycin and showing additive effects with metronidazole. Remarkably, combining the extract with clarithromycin and sub-inhibitory concentrations of pantoprazole reduced clarithromyci

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Silva, Thais M., Thays C. A. Bolzan, Marcos S. Zanini, et al. "Development and Evaluation of a Novel Oral Mucoadhesive Ointment Containing Pomegranate Peel Extract as an Adjuvant for Oral Hygiene of Dogs." Journal of Veterinary Dentistry 37, no. 3 (2020): 133–40. http://dx.doi.org/10.1177/0898756420973470.

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Herbal therapies are used worldwide to treat a variety of health conditions, including dental conditions in veterinary medicine. In this context, the use of medicinal plant-based formulations as potential therapeutics and preventatives in veterinary dentistry is worth highlighting. The objective of the present study was to develop a mucoadhesive ointment formulation, named orabase, that contained pomegranate extract for use in the oral cavity of dogs, with the aim of improving their oral hygiene. The hydroalcoholic extracts of pomegranate peels was incorporated into the orabase in 3 different

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Artem, Victoria, Arina Oana Antoce, Elisabeta Irina Geana, et al. "Circular Model for the Valorization of Black Grape Pomace for Producing Pasteurized Red Must Enriched in Health-Promoting Phenolic Compounds." Sustainability 17, no. 14 (2025): 6633. https://doi.org/10.3390/su17146633.

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As compared to red wine technology, where pomace is macerated, the grape juices and musts are obtained by pressing the grapes and removing the pomace, thus removing an important source of antioxidant molecules. The objective of this study was to exploit the bioactive compounds from the black grape pomace and obtain a new food product, namely pasteurized red must with improved health-promoting properties. The study was conducted on four grape varieties for red wines—Fetească Neagră, Cabernet Sauvignon, Blauer Zweigelt, and Arcaș—each coming from a certain recognized Romanian vineyard, as follow

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Matias, Edinardo Fagner Ferreira, Erivânia Ferreira Alves, Beatriz Sousa Santos, et al. "Biological Activities and Chemical Characterization ofCordia verbenaceaDC. as Tool to Validate the Ethnobiological Usage." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–7. http://dx.doi.org/10.1155/2013/164215.

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Knowledge of medicinal plants is often the only therapeutic resource of many communities and ethnic groups. “Erva-baleeira”,Cordia verbenaceaDC., is one of the species of plants currently exploited for the purpose of producing a phytotherapeutic product extracted from its leaves. In Brazil, its major distribution is in the region of the Atlantic Forest and similar vegetation. The crude extract is utilized in popular cultures in the form of hydroalcoholic, decoctions and infusions, mainly as antimicrobial, antiinflammatory and analgesic agents. The aim of the present study was to establish a ch

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Rendueles, Eugenia, Elba Mauriz, Javier Sanz-Gómez, Félix Adanero-Jorge, and María del Camino. "Antimicrobial Activity of Spanish Propolis against Listeria monocytogenes and Other Listeria Strains." Microorganisms 11, no. 6 (2023): 1429. http://dx.doi.org/10.3390/microorganisms11061429.

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The outbreaks of Listeria associated with food consumption are increasing worldwide concurrently with public concern about the need for natural growth inhibitors. In this context, propolis seems to be a promising bioactive product collected by honeybees, due to its antimicrobial activity against different food pathogens. This study aims to evaluate the efficacy of hydroalcoholic propolis extracts for controlling Listeria under several pH conditions. The physicochemical properties (wax, resins, ashes, impurities), the bioactive compounds (phenolic and flavonoid content), and the antimicrobial a

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Crescenzi, Maria Assunta, Antonietta Cerulli, Paola Montoro, and Sonia Piacente. "Metabolite Profiling for Typization of “Rucola Della Piana del Sele” (PGI), Eruca sativa, through UHPLC-Q-Exactive-Orbitrap-MS/MS Analysis." Foods 12, no. 18 (2023): 3384. http://dx.doi.org/10.3390/foods12183384.

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In August 2020, the Eruca sativa cultivar “Rucola della Piana del Sele” obtained from the European Union the prestigious PGI (protected geographical indication) label, which certifies the uniqueness of its characteristics and increases its prestige both nationally and, above all, internationally. This plant is recognized as a product of excellence, with a unique flavor and unmistakable aroma. Therefore, since there are no methods to characterize the PGI product, a metabolomic approach was applied to characterize E. sativa grown in the Piana del Sele and different geographical areas. As E. sati

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Avila-Ortiz, Camila Andrea, Andrés Giraldo-Toro, Valentina Guzmán, and María Soledad Hernández. "Application and sensory evaluation of a hydroalcoholic extract of nasturtium (Tropaeolum majus L.) in a beverage from tropical fruits and vegetables." Agronomía Colombiana 41, no. 1 (2023): e104490. http://dx.doi.org/10.15446/agron.colomb.v41n1.104490.

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The nasturtium is diverse in bioactive compounds such as carotenoids, anthocyanins, and glucosinolates. Due to these attributes, it is important to apply them to novel foods, such as drinks. The objective of this study was to carry out a sensory evaluation for the viability of the addition of nasturtium extract to a beverage. Solvent extraction was performed at a solute-solvent ratio of 1:10 – 1:15 and ethanol purity of 45%, 70%, or 96%; antioxidant capacity was analyzed by the FRAP method and total phenolic compounds content by the Folin-Ciocalteu method. Additionally, three samples of the be

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Spano, Mattia, Alessandro Maccelli, Giacomo Di Matteo, et al. "Metabolomic Profiling of Fresh Goji (Lycium barbarum L.) Berries from Two Cultivars Grown in Central Italy: A Multi-Methodological Approach." Molecules 26, no. 17 (2021): 5412. http://dx.doi.org/10.3390/molecules26175412.

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The metabolite profile of fresh Goji berries from two cultivars, namely Big Lifeberry (BL) and Sweet Lifeberry (SL), grown in the Lazio region (Central Italy) and harvested at two different periods, August and October, corresponding at the beginning and the end of the maturation, was characterized by means of nuclear magnetic resonance (NMR) and electrospray ionization Fourier transform ion cyclotron resonance (ESI FT-ICR MS) methodologies. Several classes of compounds such as sugars, amino acids, organic acids, fatty acids, polyphenols, and terpenes were identified and quantified in hydroalco

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Cruz-Arévalo, Julio, Víctor M. Hernández-Velázquez, Alexandre Toshirrico Cardoso-Taketa, et al. "Hydroalcoholic Extracts from Pleurotus ostreatus Spent Substrate with Nematocidal Activity against Nacobbus aberrans Phytonematode and the Non-Target Species Panagrellus redivivus." Plants 13, no. 13 (2024): 1777. http://dx.doi.org/10.3390/plants13131777.

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Pleurotus ostreatus, an edible mushroom widely consumed worldwide, generates a by-product known as spent mushroom substrate (SMS). This material has demonstrated biological activity against agricultural crop pathogens. In this study, we evaluated the nematocidal effectiveness of hydroalcoholic extracts (T5, T2, AT5, and AT2) derived from SMS of P. ostreatus against (J2) of the phytonematode Nacobbus aberrans and assessed their potential toxicity towards the non-target nematode Panagrellus redivivus. Among these extracts, AT5 exhibited the highest efficacy against N. aberrans and was the least

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Faraoni, Paola, Lorenzo Cecchi, Maria Bellumori, Alessio Gnerucci, Francesco Ranaldi, and Nadia Mulinacci. "Virgin Olive Oil By-Products: Biological Activity of Phenolic Extract of Pâté on AGS Gastric Cells." International Journal of Molecular Sciences 24, no. 9 (2023): 7959. http://dx.doi.org/10.3390/ijms24097959.

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Pâté is a by-product of olive oil production which represents an abundant source of phenolic compounds and can be used for food formulation, reducing its environmental impact and promoting a circular economy. In this context, the effects of a hydroalcoholic extract of pâté were evaluated for the first time in an AGS human cell line commonly used as model of gastric mucosa. Pâté was obtained from Tuscan olives; the total phenolic content was 16.6 mg/g dried extract, with verbascoside and secoiridoid derivatives as the most abundant phenols. The phenolic pâté extract did not alter viability, dis

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Antonacci, Marina, Jacopo Raffaele Dibenedetto, Fatima Maqoud, et al. "Counteractions of a Novel Hydroalcoholic Extract from Lens Culinaria against the Dexamethasone-Induced Osteoblast Loss of Native Murine Cells." Cells 11, no. 19 (2022): 2936. http://dx.doi.org/10.3390/cells11192936.

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The cytoprotective effects of a novel hydroalcoholic extract (0.01–5 mg/mL) from Lens culinaria (Terre di Altamura Srl) were investigated within murine native skeletal muscle fibers, bone marrow cells, and osteoblasts, and in cell lines treated with the apoptotic agent staurosporine (2.14 × 10−6 M), the alkylating drug cisplatin (10−4 M), the topoisomerase I inhibitor irinotecan (10−4 M), the antimitotic pro-oxidant doxorubicin (10−6 M), and the immunosuppressant dexamethasone (2 × 10−6 M). An amount of 10g of plant material was used to obtain a 70% ethanol/water product, following two-step ex

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Bianchi, Simone, Rosaria Acquaviva, Claudia Di Giacomo, et al. "Origanum majorana Extracts: A Preliminary Comparative Study on Phytochemical Profiles and Bioactive Properties of Valuable Fraction and By-Product." Plants 14, no. 15 (2025): 2264. https://doi.org/10.3390/plants14152264.

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Origanum majorana L. (O. majorana) (Lamiaceae) is an aromatic Mediterranean plant widely used in food, cosmetics, and traditional medicine due to its aroma and rich content of bioactive compounds. While its leaves and flowers are commonly utilized, lignified stems are often discarded. This study compared hydroalcoholic extracts from the leaves and flowers (valuable fraction, VF) and stems (by-product, BP). Phytochemical analysis revealed qualitatively similar profiles, identifying 20 phenolic compounds, with Rosmarinic acid and Salvianolic acid B as the most and second most abundant, respectiv

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Ingallina, Cinzia, Anatoly P. Sobolev, Simone Circi, Mattia Spano, Anna Maria Giusti, and Luisa Mannina. "New Hybrid Tomato Cultivars: An NMR-Based Chemical Characterization." Applied Sciences 10, no. 5 (2020): 1887. http://dx.doi.org/10.3390/app10051887.

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Bamano, King Creole, Sugarland, and DulceMiel hybrid tomato cultivars have been recently introduced in the Lazio area (Central Italy) to expand and valorize the regional/national market. Tomatoes from these cultivars, together with tomatoes from the native Fiaschetta cultivar, were sampled at the proper ripening time for the fresh market and characterized to obtain and compare their metabolite profiles. The Bligh–Dyer extraction protocol was carried out, and the resulting organic and hydroalcoholic fractions were analyzed by high-field Nuclear Magnetic Resonance (NMR) spectroscopy. NMR data re

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Ramunno, Anna, Rosa Maria Vitale, Pietro Amodeo, et al. "Bioguided Identification of Polymethoxyflavones as Novel Vascular CaV1.2 Channel Blockers from Citrus Peel." Molecules 29, no. 23 (2024): 5693. https://doi.org/10.3390/molecules29235693.

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The huge amount of citrus peel produced worldwide represents an economic burden for society. However, this agricultural by-product is a rich source of natural molecules, potentially endowed with interesting pharmacological activities. In this regard, we decided to investigate if the polymethoxyflavones contained in citrus peel waste could be exploited as novel vasorelaxant agents. A hydroalcoholic blond orange (Citrus sinensis) peel extract, obtained by ultrasonication, was partitioned in dichloromethane. Column chromatography allowed for the isolation of four polymethoxyflavones, namely, scut

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