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Journal articles on the topic 'Hydrocodone Rescheduling'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Neuman, Mark D., Sean Hennessy, Dylan S. Small, et al. "Drug Enforcement Agency 2014 Hydrocodone Rescheduling Rule and Opioid Dispensing after Surgery." Anesthesiology 132, no. 5 (2020): 1151–64. http://dx.doi.org/10.1097/aln.0000000000003188.

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Abstract Background In 2014, the U.S. Drug Enforcement Agency reclassified hydrocodone from Schedule III to Schedule II of the Controlled Substances Act, resulting in new restrictions on refills. The authors hypothesized that hydrocodone rescheduling led to decreases in total opioid dispensing within 30 days of surgery and reduced new long-term opioid dispensing among surgical patients. Methods The authors studied privately insured, opioid-naïve adults undergoing 10 general or orthopedic surgeries between 2011 and 2015. The authors conducted a differences-in-differences analysis that compared

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2

Fernandez, PharmD, BCPS, CGP, Julianna, James Douglas Thornton, PhD, PharmD, BCPS, Sanika Rege, MS, et al. "Prescribers' perceptions on the impact of hydrocodone rescheduling on geriatric pain management: A qualitative study." Journal of Opioid Management 14, no. 5 (2018): 317–26. http://dx.doi.org/10.5055/jom.2018.0464.

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Objective: To qualitatively assess prescribers’ perceptions regarding the consequences associated with hydrocodone rescheduling among geriatric patients being discharged from inpatient settings.Design: This was a cross-sectional study.Setting: Two focus groups were conducted by a trained facilitator in a metropolitan academic medical center in January 2016.Participants: Prescribers who manage noncancer pain for geriatric patients were recruited. Focus groups were recorded, transcribed, and then analyzed using ATLAS.ti Qualitative Data Analysis software. Codes were derived from six primary rese

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3

Liu, Yingna, Olesya Baker, Jeremiah D. Schuur, and Scott G. Weiner. "Effects of Rescheduling Hydrocodone on Opioid Prescribing in Ohio." Pain Medicine 21, no. 9 (2019): 1863–70. http://dx.doi.org/10.1093/pm/pnz210.

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Abstract Background We quantified opioid prescribing after the 2014 rescheduling of hydrocodone from schedule III to II in the United States using a state-wide prescription database and studied trends three years before and after the policy change, focusing on certain specialties. Methods We used Ohio’s state prescription drug monitoring program database, which includes all filled schedule II and III prescriptions regardless of payer or pharmacy, to conduct an interrupted time series analysis of the nine most prescribed opioids: hydrocodone, oxycodone, tramadol, codeine, and others. We analyze

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4

Lipman, Arthur. "AMA Fact Sheet on Hydrocodone Rescheduling." Journal of Pain & Palliative Care Pharmacotherapy 29, no. 1 (2015): 82–97. http://dx.doi.org/10.3109/15360288.2014.1003684.

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5

Yap, Diana. "FDA advisory committee recommends hydrocodone rescheduling." Pharmacy Today 19, no. 3 (2013): 71. http://dx.doi.org/10.1016/s1042-0991(15)31504-8.

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6

&NA;. "The rescheduling of hydrocodone combination products." Reactions Weekly &NA;, no. 1426 (2012): 5. http://dx.doi.org/10.2165/00128415-201214260-00014.

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7

Traynor, Kate. "FDA advisers support rescheduling of hydrocodone products." American Journal of Health-System Pharmacy 70, no. 5 (2013): 382–84. http://dx.doi.org/10.2146/news130017.

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8

Shumway, MD, John W., Renzhong Ran, MD, Jeff McClusky, BS, Pharm, et al. "Impact of rescheduling hydrocodone-combination products in an urban Texas county healthcare system." Journal of Opioid Management 14, no. 4 (2018): 257–64. http://dx.doi.org/10.5055/jom.2018.0457.

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Objective: The objective of this study was to examine the rescheduling of hydrocodone- combination products (HCPs) and associated changes in prescriber patterns in an urban county healthcare system in Texas.Methods: Pharmacy data were obtained electronically for tramadol, hydrocodone-acetaminophen, and acetaminophen-codeine from 180 days before and after the schedule change on October 6, 2014. χ2 and t tests were used to calculate the significance of changes between the medications over the studied time.Results: Hydrocodone-acetaminophen saw a decline in dispense events and pills dispensed of

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9

Liaw, Victor, Yong-Fang Kuo, Mukaila A. Raji, and Jacques Baillargeon. "Opioid Prescribing Among Adults With Disabilities in the United States After the 2014 Federal Hydrocodone Rescheduling Regulation." Public Health Reports 135, no. 1 (2019): 114–23. http://dx.doi.org/10.1177/0033354919892638.

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Objectives: Deaths from prescription opioid overdoses have reached an epidemic level in the United States, particularly among persons with disabilities. The 2014 federal rescheduling regulation is associated with reduced opioid prescribing in the general US population; however, to date, no data have been published on this regulation’s effect on persons with disabilities. We examined whether the 2014 hydrocodone rescheduling change was associated with reduced opioid prescribing among adult Medicare beneficiaries with disabilities. Methods: We identified 680 876 Medicare beneficiaries with disab

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10

Schultz, PharmD, Steven, Carol Chamberlain, PharmD, Psych MA, Marius Vulcan, MD, Humair Rana, MD, Bhavin Patel, PharmD, MBA, and John C. Alexander, MD. "Analgesic utilization before and after rescheduling of hydrocodone in a large academic level 1 trauma center." Journal of Opioid Management 12, no. 2 (2016): 119. http://dx.doi.org/10.5055/jom.2016.0323.

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Background: Hydrocodone-containing products were recently rescheduled from Drug Enforcement Agency (DEA) schedule III to schedule II due to concerns of abuse and misuse. These changes went into effect on October 6, 2014. Objective: This quality improvement project involved a retrospective analysis to determine the effect of the DEA schedule change on prescribing habits of hydrocodone-containing products as well as the remaining schedule III and IV opioids, codeine (schedule III) and tramadol (schedule IV).Methods: The authors performed a medication use evaluation at our academic level 1 trauma

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11

Collins, Sonya. "Hydrocodone rescheduling leads to drop in dispensed prescriptions, tablets." Pharmacy Today 22, no. 4 (2016): 41. http://dx.doi.org/10.1016/j.ptdy.2016.03.022.

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12

Oehler, Elizabeth C., Rachel L. Day, David B. Robinson, and Lawrence H. Brown. "Has the rescheduling of hydrocodone changed ED prescribing practices?" American Journal of Emergency Medicine 34, no. 12 (2016): 2388–91. http://dx.doi.org/10.1016/j.ajem.2016.09.002.

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13

Shumway, J. W., J. McClusky, W. F. Peacock, A. Cintron, and M. S. Ludwig. "Impact of Rescheduling Hydrocodone Combination Products Among Cancer Patients." International Journal of Radiation Oncology*Biology*Physics 99, no. 2 (2017): E527. http://dx.doi.org/10.1016/j.ijrobp.2017.06.1866.

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14

Bernhardt, M. Brooke, Ruston S. Taylor, Joseph L. Hagan, et al. "Evaluation of opioid prescribing after rescheduling of hydrocodone-containing products." American Journal of Health-System Pharmacy 74, no. 24 (2017): 2046–53. http://dx.doi.org/10.2146/ajhp160548.

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15

Hatfield, M. D., S. S. Sansgiry, M. L. Johnson, E. J. Essien, K. H. Todd, and M. L. Fleming. "RESCHEDULING HYDROCODONE COMBINATION PRODUCTS: ASSESSING THE IMPACT ON OPIOID UTILIZATION." Value in Health 19, no. 3 (2016): A255. http://dx.doi.org/10.1016/j.jval.2016.03.1020.

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16

Fleming, M. L., L. Driver, S. S. Sansgiry, et al. "IMPACT OF HYDROCODONE RESCHEDULING ON TEXAS PHYSICIANS’ FUTURE PAIN MANAGEMENT." Value in Health 19, no. 3 (2016): A258. http://dx.doi.org/10.1016/j.jval.2016.03.1037.

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17

Raji, Mukaila A., Yong-Fang Kuo, Deepak Adhikari, Jacques Baillargeon, and James S. Goodwin. "Decline in opioid prescribing after federal rescheduling of hydrocodone products." Pharmacoepidemiology and Drug Safety 27, no. 5 (2017): 513–19. http://dx.doi.org/10.1002/pds.4376.

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18

Rees, MD, MPH, Chris A., Melanie Brooke Bernhardt, PharmD, Elizabeth A. Camp, PhD, Jessica S. Lin, BA, and Corrie E. Chumpitazi, MD, MS. "Race and ethnicity: Not factors in the prescribing of hydrocodone- and codeine-containing products in two pediatric emergency departments." Journal of Opioid Management 15, no. 3 (2019): 229–33. http://dx.doi.org/10.5055/jom.2019.0506.

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Objective: To describe the prescription of hydrocodone-containing products (HCPs) and codeine-containing products (CCPs) by patient and provider race and ethnicity at two pediatric emergency departments (EDs) before and after the US Drug Enforcement Administration (DEA) rescheduling of HCPs in 2014.Design and setting: The authors performed a secondary analysis of data describing the prescription of HCPs and CCPs for 6 months before and after the DEA rescheduling of HCPs in two academic, urban pediatric EDs.Patients, participants: The authors included all children for whom race and ethnicity da

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19

Mattingly II, T. Joseph. "Rescheduling of Combination Hydrocodone Products: Problems for Long-Term Care Practitioners." Consultant Pharmacist 30, no. 1 (2015): 13–17. http://dx.doi.org/10.4140/tcp.n.2015.13.

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20

Seago, Susan, Adam Hayek, Jessica Pruszynski, and Megan Greene Newman. "Change in Prescription Habits After Federal Rescheduling of Hydrocodone Combination Products." Baylor University Medical Center Proceedings 29, no. 3 (2016): 268–70. http://dx.doi.org/10.1080/08998280.2016.11929431.

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21

Fleming, M. L., L. Driver, S. S. Sansgiry, et al. "PREDICTING TEXAS PHYSICIANS’ INTENTION TO PRESCRIBE HYDROCODONE COMBINATION PRODUCTS AFTER RESCHEDULING." Value in Health 19, no. 3 (2016): A258. http://dx.doi.org/10.1016/j.jval.2016.03.1036.

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22

Oehler, E., R. Day, B. Robinson, and L. Brown. "130 Has the Rescheduling of Hydrocodone Changed Emergency Department Prescribing Practices?" Annals of Emergency Medicine 68, no. 4 (2016): S51. http://dx.doi.org/10.1016/j.annemergmed.2016.08.142.

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23

Golembiewski, Julie. "Rescheduling of Hydrocodone Combination Products: Potential Impact and Alternatives for Postoperative Pain Management." Journal of PeriAnesthesia Nursing 30, no. 3 (2015): 244–48. http://dx.doi.org/10.1016/j.jopan.2015.01.005.

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24

Chumpitazi, Corrie E., Chris A. Rees, Elizabeth A. Camp, and M. Brooke Bernhardt. "Decreased Opioid Prescribing in a Pediatric Emergency Department After the Rescheduling of Hydrocodone." Journal of Emergency Medicine 52, no. 4 (2017): 547–53. http://dx.doi.org/10.1016/j.jemermed.2016.08.026.

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25

Covvey, Jordan, Andrea Pfalzgraf, and Peter Cohron. "U.S. Pharmacist Opinions Regarding the Rescheduling of Hydrocodone Combination Products: A Pilot Study." Pharmacy 3, no. 3 (2015): 129–36. http://dx.doi.org/10.3390/pharmacy3030129.

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26

Kuo, Yong‐Fang, Mukaila A. Raji, Victor Liaw, Jacques Baillargeon, and James S. Goodwin. "Opioid Prescriptions in Older Medicare Beneficiaries After the 2014 Federal Rescheduling of Hydrocodone Products." Journal of the American Geriatrics Society 66, no. 5 (2018): 945–53. http://dx.doi.org/10.1111/jgs.15332.

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27

Chambers, Jan, Rae M. Gleason, Kenneth L. Kirsh, et al. "An Online Survey of Patients’ Experiences Since the Rescheduling of Hydrocodone: The First 100 Days." Pain Medicine 17, no. 9 (2015): 1686–93. http://dx.doi.org/10.1093/pm/pnv064.

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28

Fleming, Marc L., Larry Driver, Sujit S. Sansgiry, et al. "Physicians' intention to prescribe hydrocodone combination products after rescheduling: A theory of reasoned action approach." Research in Social and Administrative Pharmacy 13, no. 3 (2017): 503–12. http://dx.doi.org/10.1016/j.sapharm.2016.07.001.

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29

Bapat, S., J. D. Thornton, and M. L. Fleming. "PMU49 CHANGES IN ANALGESIC PRESCRIBING AMONG TEXAS ADVANCED PRACTICE PROVIDERS AFTER RESCHEDULING OF HYDROCODONE COMBINATION PRODUCTS." Value in Health 22 (May 2019): S257—S258. http://dx.doi.org/10.1016/j.jval.2019.04.1211.

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30

Varisco, Tyler J., Motolani E. Ogunsanya, Jamie C. Barner, and Marc L. Fleming. "Pharmacists’ perceptions regarding the impact of hydrocodone rescheduling on prescription volume, workflow management, and patient outcomes." Journal of the American Pharmacists Association 57, no. 2 (2017): S51—S62. http://dx.doi.org/10.1016/j.japh.2017.01.020.

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31

Jones, Christopher M., Peter G. Lurie, and Douglas C. Throckmorton. "Effect of US Drug Enforcement Administration’s Rescheduling of Hydrocodone Combination Analgesic Products on Opioid Analgesic Prescribing." JAMA Internal Medicine 176, no. 3 (2016): 399. http://dx.doi.org/10.1001/jamainternmed.2015.7799.

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32

Haider, Ali, Joseph Baidoo, Yee Choon Meng, et al. "Changes in opioid type and dose among cancer patients referred to outpatient palliative care." Journal of Clinical Oncology 34, no. 26_suppl (2016): 106. http://dx.doi.org/10.1200/jco.2016.34.26_suppl.106.

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106 Background: Opioid prescriptions are regulated at both federal and state levels. Examples of such regulations include use of risk evaluation and mitigation strategies (REMS), mandatory sharing of prescription data with state prescription drug monitoring programs and the reclassification of hydrocodone as schedule II opioid in October 2014. One possible consequence of such changes would be earlier referral to palliative care (PC) for opioid management. Alternatively, primary oncologist may treat patients with weak opioids or use strong opioids with lower daily dose. We hypothesized that dur

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33

Fleming, Marc L., Larry Driver, Sujit S. Sansgiry, et al. "Drug Enforcement Administration Rescheduling of Hydrocodone Combination Products Is Associated With Changes in Physician Pain Management Prescribing Preferences." Journal of Pain & Palliative Care Pharmacotherapy 33, no. 1-2 (2019): 22–31. http://dx.doi.org/10.1080/15360288.2019.1615027.

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34

Winbigler, Brian L., Michael G. O’Neil, Jeremy Crain, A. Shaun Rowe, and Katherine A. Ryan. "Rescheduling hydrocodone combination products: Impact on patients receiving long-term HCP therapy in a large chain pharmacy—A statewide assessment." Journal of the American Pharmacists Association 60, no. 2 (2020): 374–78. http://dx.doi.org/10.1016/j.japh.2019.10.002.

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35

Mallama, Celeste, Sara Karami, Di Zhang, et al. "The impact of more restrictive hydrocodone rescheduling on unintentional pediatric opioid exposures." Pharmacoepidemiology and Drug Safety 33, no. 6 (2024). http://dx.doi.org/10.1002/pds.5793.

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AbstractPurposeTo evaluate the impact of rescheduling hydrocodone combination products (HCPs) from schedule III of the Controlled Substances Act to the more restrictive schedule II on unintentional pediatric exposures (≤5 years old).MethodsUsing U.S. data on outpatient retail pharmacy dispensing, emergency department (ED) visits, and poison center (PC) exposure cases, we assessed trends in prescriptions dispensed and unintentional pediatric exposure cases involving hydrocodone (rescheduled from III to II) compared to oxycodone (schedule II) and codeine (schedule III for combination products) u

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36

Pergolizzi, JV, F. Breve, R. Taylor, G. Zampogna, and JA LeQuang. "The Aftermath of Hydrocodone Rescheduling: Intentional and Unintended Consequences." January 11, 2017. https://doi.org/10.19070/2332-2780-1600078.

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The U.S. consumes about 99% of the world’s supply of hydrocodone, primarily in hydrocodone combination products (HCPs). The Drug Enforcement Administration’s (DEA) rescheduling of HCPs from Schedule III to the more restrictive Schedule II has changed prescribing patterns. The purpose of our article was to revisit HCP rescheduling to determine the impact this change had and its related consequences. Before 2014, DEA drug classification (scheduling) caused the “Vicodin loophole” which allowed HCP products to be prescribed under less restrictive conditions than single-entity hydrocodone products

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37

Yan, C. H., C. C. Hubbard, T. A. Lee, et al. "Impact of Hydrocodone Rescheduling on Dental Prescribing of Opioids." JDR Clinical & Translational Research, June 16, 2022, 238008442211028. http://dx.doi.org/10.1177/23800844221102830.

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Introduction: In the United States, dentists frequently prescribe hydrocodone. In October 2014, the US Drug Enforcement Administration rescheduled hydrocodone from controlled substance schedule III to II, introducing more restricted prescribing and dispensing regulations, which may have changed dental prescribing of opioids. Objective: The study aim was to evaluate the impact of the hydrocodone rescheduling on dental prescribing of opioids in the United States. Methods: This was a cross-sectional study of opioids prescribed by dentists between October 2012 and October 2016, using the IQVIA Lon

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38

JV, Pergolizzi, Breve F, Taylor R, and LeQuang JA. "The Aftermath of Hydrocodone Rescheduling: Intentional and Unintended Consequences." International Journal of Anesthesiology & Research, January 11, 2017, 377–82. http://dx.doi.org/10.19070/2332-2780-1600078.

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39

Olvera, Johabed G., Felipe Lozano-Rojas, Julio A. Ramos Pastrana, and Sumedha Gupta. "Opioids Prescribing Restrictions and Homelessness: Evidence from Hydrocodone Rescheduling." Journal of Housing Economics, June 2024, 102010. http://dx.doi.org/10.1016/j.jhe.2024.102010.

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40

Olvera, Johabed G., Felipe Lozano-Rojas, Julio Alberto Ramos Pastrana, and Sumedha Gupta. "Opioids Prescribing Restrictions and Homelessness: Evidence from Hydrocodone Rescheduling." SSRN Electronic Journal, 2023. http://dx.doi.org/10.2139/ssrn.4386200.

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41

Lozano‐Rojas, Felipe, and Mikhail Ivonchyk. "Opioid Epidemic and Local Fiscal Choices: Causal Evidence From Hydrocodone Rescheduling." Public Budgeting & Finance, December 11, 2024. https://doi.org/10.1111/pbaf.12385.

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ABSTRACTThe opioid epidemic has garnered attention from scholars across disciplines, yet its effect on local finances remains uncertain. We exploit an exogenous shock in hydrocodone supply, a commonly abused opioid, to estimate the causal effect of opioid exposure on local finances. Our results reveal larger budgets in affected communities, driven primarily by increased healthcare spending, along with higher intergovernmental aid and property taxes, while other revenue sources remain largely unchanged. These findings indicate that the epidemic burdens local budgets and suggest that addressing

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42

Usmani, Silken A., Josef Hollmann, Amie Goodin, et al. "Effects of hydrocodone rescheduling on opioid use outcomes: A systematic review." Journal of the American Pharmacists Association, October 2020. http://dx.doi.org/10.1016/j.japh.2020.09.013.

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43

Karami, Sara, Adebola Ajao, Jennie Wong, et al. "The Impact of Hydrocodone Rescheduling on Utilization, Abuse, Misuse, and Overdose Deaths." Pharmacoepidemiology and Drug Safety, February 13, 2023. http://dx.doi.org/10.1002/pds.5603.

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44

Fischer, Laura J., Stevan G. Severtson, Marie C. Gurrola, Janetta L. Iwanicki, Jody L. Green, and Richard C. Dart. "Changes in Hydrocodone Misuse Exposures Reported to U.S. Poison Centers Following Rescheduling in 2014." Substance Use & Misuse, April 22, 2022, 1–7. http://dx.doi.org/10.1080/10826084.2022.2063898.

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45

Lozano-Rojas, Felipe. "How Do Local Government Finances Respond to the Opioid Epidemics? Evidence From Hydrocodone Rescheduling." SSRN Electronic Journal, 2020. http://dx.doi.org/10.2139/ssrn.3666448.

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46

Lozano-Rojas, Felipe, and Amanda J. Abraham. "A Gateway to Misuse? Synthetic Opioid Mortality and the Rescheduling of Hydrocodone in the United States." SSRN Electronic Journal, 2024. https://doi.org/10.2139/ssrn.5044591.

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47

Wu, Alice, Christine Phan, Kim Chi Nguyen, Melvin Quindoy, Justin Lewis, and Dorie E. Apollonio. "Trends in hydrocodone combination product exposures reported to California Poison Control System (CPCS) following DEA rescheduling." Clinical Toxicology, August 25, 2020, 1–7. http://dx.doi.org/10.1080/15563650.2020.1803350.

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48

Wassef, Christina, Alexander Frangenberg, HaEun Lee, et al. "Postoperative emergency department visits for pain after outpatient orthopaedic surgery: did rescheduling hydrocodone make a difference?" Current Orthopaedic Practice Publish Ahead of Print (March 3, 2023). http://dx.doi.org/10.1097/bco.0000000000001201.

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49

"Fewer hydrocodones prescribed after rescheduling in US." Reactions Weekly 1587, no. 1 (2016): 8. http://dx.doi.org/10.1007/s40278-016-14327-5.

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50

"Fewer hydrocodones prescribed after rescheduling in US." PharmacoEconomics & Outcomes News 746, no. 1 (2016): 21. http://dx.doi.org/10.1007/s40274-016-2799-5.

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