Relevant bibliographies by topics / Hydroethanolic leaves extract

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Academic literature on the topic 'Hydroethanolic leaves extract'

Author: Grafiati
Published: 3 June 2025
Last updated: 22 June 2025

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Journal articles on the topic "Hydroethanolic leaves extract"

1

Shireen Farhana. S, Usharani Boopathy, Shobana Chandrasekar, and Rohini Durairaj. "Qualitative And Quantitative Analysis of Cinnamomum Tamala Leaf Extract." Journal of Advanced Zoology 44, S5 (2023): 3071–81. http://dx.doi.org/10.17762/jaz.v44is5.2390.

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Objective: The purpose of the study is to assess the properties and bioactive components of Cinnamomum tamala leaves. Methods: The leaves of Cinnamomum tamala were extracted. Different experimental methods have been used to study the phytochemicals (qualitative and quantitative). The phytochemical screening was evaluated in different extractions such as aqueous, hexane, ethanol, petroleum ether and hydroethanolic to compare the solubility of various bioactive components. Further, high performance liquid chromatography (HPLC) and gas chromatography mass spectrometry (GC-MS) were also performed to study the presence of flavonoids and secondary metabolites respectively. Results: The Qualitative analysis showed the presence of phytochemical compounds in higher concentration in hydroethanolic extract of the leaves of Cinnamomum tamala. In comparison with other extracts, hydroethanolic extract had larger yields of flavonoids (186.42 ± 13.04 mg/g QE), phenols (226.34 ± 15.84 mg/g GAE), saponins (112.10 ± 7.84 mg/g) and steroids (161.30 ± 11.29 mg/g CL). HPLC analysis revealed the presence of flavonoids in hydroethanolic extracts of the leaves of Cinnamomum tamala. GC-MS analysis proved the presence of various bioactive compounds in the hydroethanolic extract of the leaves of Cinnamomum tamala. Conclusion: The results of this study demonstrated the significance of the leaves of Cinnamomum tamala. We concluded that Cinnamomum tamala leaves have various biological activities which can treat diseases..
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Zouheira, Djamila, Sylvie Lea Wansi Ngnokam, Sylviane Laure Poualeu Kamani, et al. "In Vitro Antilipidic and Antithrombotic Activities of Plectranthus glandulosus (Lamiaceae) Leaves Extracts and Fractions." BioMed Research International 2022 (February 7, 2022): 1–14. http://dx.doi.org/10.1155/2022/4145659.

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Objective. The present study investigated the effect of the leaves extracts and fractions of Plectranthus glandulosus on the inhibition of pancreatic lipase, cholesterol esterase, adipocytes lipid uptake, and antithrombotic activity which may be important in atherosclerosis development. Methods. Aqueous, ethanolic, and hydroethanolic extracts of Plactranthus glandulosus were prepared by maceration. The hydroethanolic extract was fractionated into n-hexane, ethylacetate, and n-butanol fractions and their inhibition of pancreatic lipase, cholesterol esterase, adipocytes lipid uptake, and antithrombotic activities measured. Liquid chromatography-high resolution mass spectrometry (LC-HRMS) analysis was carried out to determine phytochemical constituents present in the extracts. Results. The standard orlistat exhibited a higher inhibitory activity on pancreatic lipase and cholesterol esterase (16.31 μg/mL and 15.75 μg/mL, respectively) compared to ethyl acetate fraction (IC50, 17.70 μg/mL and IC50, 24.8 μg/mL, respectively). Among crude extract, hydroethanolic extract showed a better inhibition against pancreatic lipase (IC50, 21.06 μg/mL) and cholesterol esterase (IC50, 25.14 μg/mL) though not comparable to the effect of orlistat. The best lipid uptake inhibition was observed in the hydroethanolic extract (IC50, 45.42 μg/mL) followed by the ethyl acetate fraction (IC50, 47.77 μg/mL). A better antithrombolytic activity was exhibited by the ethyl acetate fraction at all concentrations (50-800 μ/mL), while hydroethanolic extract exhibited the best activity among crude extract. However, these were not comparable to the standard aspirin. The LC-HRMS analysis revealed the presence of 7-O-methyl luteolin 5-O-β-D-glucopyranoside, chrysoeriol 5-O-β-D-glucopyranoside, 5,7-dihydroxy-3,2 ′ ,4 ′ -trimethoxyflavone, and plectranmicin as major compounds in both hydroethanolic extract and ethyl acetate fraction. Conclusion. Thus, our finding supports the traditional use of this plant, which might provide a potential source for future antiatherosclerotic drug discovery.
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Ouattara, Anzoumana Lassinan, Ouattara Abou, Dominique Konan Tano, and Akissi Jeanne Koffi. "Phenolic Compound Content and Antioxidant Activity of Extracts from the Leaves of Anogeissus leiocarpus (Combretaceae), a Plant Used in the North of Côte d'Ivoire for the Traditional Treatment of Gastrointestinal Disorders in Broiler Chickens." International Journal of Biochemistry Research & Review 33, no. 4 (2024): 52–61. http://dx.doi.org/10.9734/ijbcrr/2024/v33i4869.

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Anogeissus leiocarpus (Combretaceae) (DC.) Guill. & Perr. is a plant found in West Africa, from Senegal to Cameroon and extending to Ethiopia and East Africa. In the north of Côte d’Ivoire, this plant is commonly used by livestock farmers to treat various pathologies, including digestive and gastrointestinal disorders. The aim of this study was to determine the phenolic compound content and antioxidant properties of 70% hydroethanol and aqueous extracts of A. leiocarpus’ leaves. Phenolic compound contents were determined by spectrophotometric methods. Antioxidant activities were assessed using ABTS, DPPH and FRAP tests. The 70% hydroethanolic and aqueous extracts of A. leiocarpus presented roughly equivalent concentrations of total polyphenols (608.41 and 558.25 mg EAG/g respectively). However, the hydroethanolic extract was richer in flavonoids (539.60 mg EQ/g) than the aqueous extract (388.95 mg EQ/g). In addition, the average inhibition rate of the ABTS radical in the presence of the 70% hydroethanol extract was 11.56 µM Trolox equivalent/g, compared with 8.32 µM Trolox equivalent/g with the aqueous extract. The average chelation percentages were 31.93% (70% hydroethanol extract) and 20.92% (aqueous extract). As for the reduction of DPPH radical, the ICs50 for the 70% hydroethanol and aqueous extracts were 4.4 mg/mL and 6.0 mg/mL respectively. This study confirms that Anogeissus leiocarpus is a plant containing phenolic compounds. The presence of these phenolic compounds in this plant, together with its antioxidant activities with low values (IC50), could justify its widespread use by livestock farmers in northern Côte d'Ivoire, particularly those rearing broiler chickens.
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EVENAMEDE, Kodjo Selom, Yaovi Samuel APETI, Mamatchi MELILA, Kafui KPEGBA, Amegnona AGBONON, and Oudjaniyobi SIMALOU. "Phytochemical Study and Evaluation of the Nutritional Potential of Glyphaea brevis Leaves from the Flora of Togo." Chemical Science International Journal 34, no. 3 (2025): 24–37. https://doi.org/10.9734/csji/2025/v34i3965.

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Glyphaea brevis is a food plant used in traditional medicine to treat hypertension and a number of infectious diseases. It has been the subject of very few studies and there is little data on its nutritional value. The aim of the present study is therefore to exploit the leaves of Glyphaea brevis from Togolese flora. Aqueous and hydroethanolic extracts were obtained by maceration of leaf powder. Phytochemical tests and polyphenol and flavonoid assays were carried out using colorimetric methods. Antioxidant activity was assessed in vitro using the DPPH radical scavenging test and the FRAP test. The nutritional value of Glyphaea brevis leaves was assessed using standard AOAC methods, and toxicity was assessed using an acute toxicity test in wistar rats. Phytochemical screening revealed the presence of flavonoids, saponosides, tannins, gallic tannins, terpenoids and mucilages in the aqueous extract. In addition to these compounds, anthocyanins and terpenes were found in the hydroethanol extract. The determination of polyphenols and flavonoids in the considered extracts showed that the hydroethanolic extract of the leaves contained the highest levels of these phenolic compounds: 200.893 ± 4.805 mgEAG/gE for polyphenols and 74.034 ± 2.815 mgEQ/gE for flavonoids respectively. The IC50 for antiradical compounds (DPPH●) were 1271.136 ± 3.204 μg/mL for the hydroethanolic extract and 1535 ± 2.310 μg/mL for the aqueous extract and the antioxidant activity with the FRAP test was 914.333 ± 2.205 μmol/L and 440.966 ± 1.105 μmol/L respectively. The levels of biochemical compounds were 64.99% for digestible carbohydrates, 12.14% for fibre, 19.03% for protein and 3.84% for fats. The energy value was 393.85 Kcal/100g DM. Spectrophotometer assays revealed the presence of minerals such as Na, Ca, Mg, K and Fe at significant levels, with a Na/K ˂ 1 ratio. The acute toxicity test did not reveal any signs of toxicity. All the results obtained in this study therefore justify the therapeutic and dietary use of Glyphaea brevis leaves.
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Rahayu, Ika, Susana Elya Sudrajat, Sancnia Sancnia, Monica Puspasari, and Kris Herawan Timotius. "The Phytochemical constituents and biological activities of sungkai (Peronema canescens Jack) leaves hydroethanolic extracts." JPBIO (Jurnal Pendidikan Biologi) 9, no. 1 (2024): 123–32. http://dx.doi.org/10.31932/jpbio.v9i1.3398.

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Peronema canescens, Jack commonly known as "sungkai," has been traditionally used as a herbal medicine for various health conditions. This study aimed to explore the bioactive compound of the P. canescens leaves hydroethanolic extract, along with assessing its antioxidant and antimutagenic properties. Liquid chromatography-mass spectrometry (LC-MS) was utilized for phytochemical analysis of the hydroethanolic extracts, while antioxidant activity was evaluated through the DPPH radical scavenging method. Quantification of total phenolic and flavonoid content was achieved via colorimetric analysis. Furthermore, the DNA protection activity was assessed using plasmid pBR322 subjected to free radical treatment. The primary bioactive compounds identified in the P. canescens hydroethanolic extracts belonged to the alkaloid and flavonoid groups. The antioxidant activity of P.canescens leaves hydroethanolic extracts showed an IC50 value of 0.02±0.00 µg/mL. Additionally, the total flavonoid and phenolic content were measured at 33,769±3,626 µg QE/mL and 638,924±6,683 µg GAE/mL, respectively. Notably, P.canescens exhibited significant potential in mitigating DNA damage. In conclusion, the P. canescens leaves hydroethanolic extracts demonstrate promising attributes as a herbal medicine, highlighting notable antioxidant and antimutagenic effects.
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Ni Putu Ermi Hikmawanti, Hayati, and Yeni Andriyani. "Total Flavonoid Content in Hydro-ethanolic Extract of Sauropus androgynus (L.) Merr Leaves from Three Regions with Different Altitude." Jurnal Jamu Indonesia 6, no. 2 (2021): 61–67. http://dx.doi.org/10.29244/jji.v6i2.195.

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Sauropus androgynus (L.) Merr (Phyllanthaceae), also known as katuk in Indonesia, is a plant that grows in tropical climates. The study aimed to determine the total flavonoid levels of hydroethanolic extract of katuk leaves from three regions with different altitudes. Dried katuk leaves were macerated using hydroethanolic (the mixture of ethanol:H2O (7:3, v/v)) as solvent extraction at room temperature. Determination of flavonoid levels was carried out by the colorimetry method using AlCl3 reagent. Quercetin was used as a reference. A UV-Visible spectrophotometer measured the absorbance at the maximum wavelength of 434.50 nm. The total flavonoids level of hydroethanolic extract of katuk leaves from a different region with low-altitude (Bogor), medium-altitude (Sleman), and high-altitude (Bandung) are 8.56±0.63 mgQE/g, 4.67±0.30 mgQE/g, and 9.72±0.24 mgQE/g, respectively. Thus, it can be concluded that there are differences in total flavonoid levels of hydroethanolic extract of katuk leaves from three regions with different altitudes.
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Tokoudagba, Kossi Jean Marie D., Alban G. Houngbèmè, Habib Ganfon, et al. "Isolation of Biomolecules from the Leaves of Lecaniodiscus cupanoides (Sapindaceae), a Plant used in Traditional Medicine in Benin." Asian Journal of Applied Chemistry Research 14, no. 3 (2023): 39–47. http://dx.doi.org/10.9734/ajacr/2023/v14i3269.

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The aim of the present study was to identify the structure of the bioactive molecules in the active ethyl acetate fraction of the hydroethanolic extract of Lecaniodiscus cupanoides (Sapindaceae), a Beninese plant used in the treatment of microbial infections. We prepared the hydroethanolic extract from powdered dried leaves. We fractionated the hydroethanol extract using the liquid-liquid extraction method with solvents of increasing polarity. The active ethyl acetate fraction obtained after bioguided fractionation of the hydroethanol extract on bacterial strains was purified by a series of atmospheric pressure column chromatographic methods coupled with thin layer chromatography. At the end of this purification process, three compounds, including a flavonoid and two fatty acids, were isolated and identified by interpretation of 1H NMR, 13C NMR and mass spectrometry spectra. These were: 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-2,3-dihydrochromen-4-one;(E)-3-(3,4-dihydroxyphenyl)-2-(3-(3,4-dihydroxyphenyl) acryloyloxy) propanoic acid and (E)octadec -9- enoic acid (oleic acid).
 The added value of this work lies in the fact that these three molecules have never before been identified in this plant, and therefore represent a potential avenue for the development of a therapeutic arsenal to combat microbial infections.
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Moyo, Batanai, and Stanley Mukanganyama. "The Anticandidal and Toxicity Properties of Lampranthus francisci." Journal of Mycology 2015 (October 15, 2015): 1–15. http://dx.doi.org/10.1155/2015/898202.

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Fungal infections have been rising due to the increasing number of immunocompromised patients and intensive use of some antifungal agents. Lampranthus francisci is an ornamental succulent plant. In Zimbabwe, the fresh sap from the leaves is used to treat fungal scalp infections. The activity of L. francisci fresh and dry acetone, ethanol, hydroethanolic, and aqueous extracts against Candida albicans and Candida krusei was determined. Mouse peritoneal cavity cells and sheep red blood cells were used to investigate L. francisci’s toxicity profile. The hydroethanolic extracts were the most effective extracts against C. albicans. The fresh ethanol extract was the most effective extract against C. krusei. The dry acetone extract, dry ethanol extract, and the fresh and dry aqueous extracts promoted the growth of C. krusei. The hydroethanolic extracts caused haemolysis of sheep cells. The hydroethanolic extracts promoted the growth of the mouse peritoneal cavity red blood cells. Both aqueous extracts increased the density of the mouse cells, but only the fresh extract increased the metabolism of the mouse cells. L. francisci has some fungicidal activity and boosts the growth of immune cells, thus validating its use in ethnomedicine. L. francisci extracts are potential leads for the isolation of immune stimulatory compounds.
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9

O R, Kasthuri, and Ramesh B. "PHYTOCHEMICAL SCREENING AND IN VITRO ANTIOXIDANT ACTIVITIES OF LEAF EXTRACTS OF ALTERNANTHERA BRASILIANA (L). KUNTZE AND ALTERNANTHERA BETTZICKIANA REGEL." Asian Journal of Pharmaceutical and Clinical Research 11, no. 6 (2018): 266. http://dx.doi.org/10.22159/ajpcr.2018.v11i6.25136.

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Objectives: The present study was carried out to determine the phytochemical constituents and in vitro antioxidant activities of leaf extracts of Alternanthera brasiliana (L). Kuntze (A. brasiliana) and Alternanthera bettzickiana regel (A. bettzickiana).Methods: Preliminary phytochemical screening was performed in petroleum ether, chloroform, acetone, ethanol, hydroethanolic and water extracts of leaves of A. brasiliana and A. bettzickiana. The level of alkaloids, flavonoids, total phenolic content, tannins, Vitamin C, Vitamin E, GSH, and total proteins were determined in hydroethanolic, ethanol, and water extracts. Antioxidant activity of the hydroethanolic leaf extracts of A. brasiliana and A. bettzickiana were determined by 2,2-diphenyl-1-picryl-hydrazyl-hydrate free radical scavenging assay, nitric oxide scavenging assay, superoxide anion scavenging assay, ferric reducing antioxidant power assay, total antioxidant capacity, and reducing power assay.Results: The phytochemical screening of six different extracts of A. brasiliana and A. bettzickiana revealed the presence of various phytonutrients. Quantitative analysis of secondary metabolites in ethanol, hydroethanolic and water extracts of leaves of A. brasiliana and A. bettzickiana showed the presence of high amount of secondary metabolites in the hydroethanolic extract. In vitro, antioxidant assay of two plant extracts revealed that A. bettzickiana was more potent than A. brasiliana in scavenging free radicals.Conclusion: The different extracts from A. brasiliana and A. bettzickiana and specifically the hydroethanolic extract of A. bettzickiana revealed several properties such as rich source of phytonutrients, higher free radical scavenging properties, and significant antioxidant capabilities. Therefore, the bioactive compound should be isolated in future studies and could be used as a safe and serve as a potential source of natural antioxidants.
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Antunes, Kátia Avila, Débora da Silva Baldivia, Paola dos Santos da Rocha, et al. "Antiobesity Effects of Hydroethanolic Extract of Jacaranda decurrens Leaves." Evidence-Based Complementary and Alternative Medicine 2016 (2016): 1–8. http://dx.doi.org/10.1155/2016/4353604.

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Obesity is a worldwide epidemic that reduces life expectancy; therefore, the search for new alternative and effective treatments is ongoing. The aim of the present investigation was to identify the chemical compounds in the hydroethanolic extract of leaves of Jacaranda decurrens subsp. symmetrifoliolata and to evaluate their toxicity and antiobesity effects. High-performance liquid chromatography was used to identify the chemical constituents, and acute toxicity was evaluated in rats treated with doses of 2 and 5 g·kg−1 body mass. The antiobesity effect was determined in rats with hypercaloric diet-induced obesity. Our results revealed the presence of compounds, such as jacaric, ursolic, and oleic acids, as well as luteolin, quercetin, and kaempferol, in the extract. The acute toxicity tests revealed that rats treated with elevated doses of the extract showed no signs of toxicity. The extract induced reduction in total body mass and the white adipose tissue depots. The obese rats treated with the extract showed an increased fluid intake and feces excretion while their serum total cholesterol and triglyceride levels decreased compared to those in the controls, without any hematological changes. Taken together, the results showed that the constituents of J. decurrens extracts included phenolic compounds and exhibited antiobesity effects with no toxicity.
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Book chapters on the topic "Hydroethanolic leaves extract"

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Ayembilla, Jacob Apibilla, Phyllis Naa Yarley Otu, Eunice A. Dotse, et al. "Antioxidant and Anticancer Potential of Natural Cocoa Extract." In Technological Innovation Driving Sustainable Entrepreneurial Growth in Developing Nations. IGI Global, 2023. http://dx.doi.org/10.4018/978-1-6684-9843-9.ch007.

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The aim of this study was to investigate antioxidant and anticancer potentials of natural cocoa extracts. Antioxidant properties of the extracts were evaluated by DPPH assay, total phenolic content by Folin-Ciocalteau and reduced glutathione content by O-phthalaldehyde assays. Antiproliferative activity was also evaluated on leukaemia and prostate cancer cell lines using MTT assay. The hydroethanolic extracts of cocoa roots and beans and aqueous cocoa leaves showed high total antioxidant activities with the root extract having the strongest scavenging effect on DPPH and the highest total phenolics content. The hydroethanolic cocoa bean crude extract showed the highest anticancer activity against LNCaP cells, whiles the ethyl acetate fraction of hydroethanolic cocoa leaf exhibited the highest anticancer against PC3. Jurkat and PC3 cells had similar susceptibilities to the natural cocoa extracts. Thus, cocoa has antioxidant and anticancer activity, and the specific bioactive compounds responsible for these activities need to be elucidated in future research.
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Conference papers on the topic "Hydroethanolic leaves extract"

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Sousa, Matheus Henrique Oliveira de, Gilvan de Oliveira Costa Dias, and Joselene Ribeiro de Jesus Santos. "Phytochemical prospecting, identification and evaluation of the microbiological activity of secondary metabolites of Annona mucosa Jacq." In V Seven International Multidisciplinary Congress. Seven Congress, 2024. http://dx.doi.org/10.56238/sevenvmulti2024-049.

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The present work describes the results obtained for the phytochemical and microbiological studies of the 70% hydroethanolic extract, its fractions and metabolites isolated from the leaves of Biribazeiro ( Annona mucosa Jacq.). Initially, the hydroethanolic extract (70%) of the vegetable leaves was prepared and a phytochemical screening was carried out in search of the secondary metabolites of study. The tests confirmed the presence of tannins, flavonols, flavanones, flavanonols, xanthones, leucoanthocyanidins, anthocyanidins, free steroids,
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Mayorga, O., J. Florencio, B. Santos, O. do Amaral Corrêa José, O. Sousa, and S. Alves Maria. "Topical anti-inflammatory activity of the hydroethanolic extract from Kalanchoe brasiliensis Cambess. (Crassulaceae) leaves." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608178.

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