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Journal articles on the topic 'Hydromorphie'

Author: Grafiati

Published: 4 June 2021

Last updated: 18 February 2022

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1

LEVY, G. "Plantations sur sols à hydromorphie temporaire." Revue Forestière Française, no. 3 (1986): 307. http://dx.doi.org/10.4267/2042/25657.

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LÉVY, G., N. LE GOFF, Sabine GIRARD, and Y. LEFÈVRE. "Potentialités de l'Alisier torminal sur sols à hydromorphie temporaire : comparaison avec les Chênes pédonculé et sessile." Revue Forestière Française, no. 3 (1993): 243. http://dx.doi.org/10.4267/2042/26419.

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3

Béjaoui, Zoubeir, Ali Albouchi, Mejda Abassi, and Mohamed Hédi El Aouni. "Influence d'une hydromorphie modérée ou sévère sur la production de biomasse et les échanges gazeux de plants de peuplier euraméricain." Canadian Journal of Forest Research 36, no. 10 (2006): 2654–65. http://dx.doi.org/10.1139/x06-145.

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Seedlings of three poplar clones (I-488, Rimini, and D-64) grown in plastic pots were submitted to three water regimes: (1) irrigated and well-drained control (T); (2) flooded with running water (Hr = 6 mg·L–1 of O2); and (3) flooded with stagnant water (Hs = 2 mg·L–1 of O2). A permanent water table was maintained at 5 cm above the soil surface for 2 months. The Hr and Hs treatments simulate the conditions of hydromorphic soils chosen for planting poplar in Tunisia where the attempts failed because of the lack of knowledge relating to the degree of tolerance of this species to waterlogging. Wa

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LÉVY, G. "Incidences possibles d'une coupe à blanc sur la remontée des nappes et la stabilité structurale des sols à hydromorphie temporaire." Revue Forestière Française, no. 5 (1990): 517. http://dx.doi.org/10.4267/2042/26101.

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5

Damaceno, João Batista Dias, Wellington Gomes da Silva, Hedinaldo Narciso Lima, et al. "Physical, Chemical, Morphological and Mineralogical Characterization Surface and Subsurface in Hydromorphic and Non-hydromorphic Soil of the Central Amazon." Journal of Agricultural Science 12, no. 4 (2020): 245. http://dx.doi.org/10.5539/jas.v12n4p245.

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Amazonian soils have some physical, chemical and mineralogical differences, understanding the differences is important to understand the behavior of nutrients in the soil, especially phosphorus. The study was carried out in two types of soils: a Hydromorphic soil profile and a Non-hydromorphic soil profile in the Central Amazon region of Brazil, located in the metropolitan area of Manaus. Five depths were sampled: 0.00-0.05; 0.05-0.1; 0.1-0.2; 0.2-0.4; and 0.4-0.6 m. Physical, chemical, mineralogical and morphological attributes of both soils were studied. With the exception of clay, the level

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Vodyanitskii, Yuriy, and Tatiana Minkina. "Changing the properties of samples after extraction from wet soil: a short review." Geochemistry: Exploration, Environment, Analysis 20, no. 4 (2020): 399–407. http://dx.doi.org/10.1144/geochem2020-033.

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Laboratory-dried specimens yield distorted information about the state of hydromorphic soil. Changes in the gas medium, humidity, temperature, aggregation capacity and illumination have an irreversible impact on the dried and powdered soil specimen. Properties of the dried hydromorphic soil can be altered significantly. Most altered are (1) the colour of the hydromorphic soils, (2) the рН value, and (3) the content of mobile trace metal (TM) compounds after drying the wet soil. Colour change (browning) of the hydromorphic soil is related to the oxidation of Fe(II). In a highly ferruginous soil

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7

Lange, Benjamin, Peter F. Germann, and Peter Lüscher. "Einfluss der Wurzeln auf das Wasserspeichervermögen hydromorpher Waldböden | Significance of roots for soil water storage capacity of hydromorphic forest soils." Schweizerische Zeitschrift fur Forstwesen 161, no. 12 (2010): 510–16. http://dx.doi.org/10.3188/szf.2010.0510.

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In this study we investigated the significance of roots for the water storage capacity of hydromorphic forest soils in the northern Pre-Alps of Switzerland. Irrigation experiments were conducted on 1 m2 plots with high initial soil water content. A total of 67 horizons were investigated for water content variations using time domain reflectometry (TDR). The data was processed using a physically based model, which assumes gravity-driven and viscosity-controlled water flow along pore walls in the form of thin water films. The model calculates the contact length (L) between mobile water and the s

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8

Petosić, D., V. Kovacević, and M. Josipović. "Phosphorus availability in hydromorphic soils of Eastern Croatia." Plant, Soil and Environment 49, No. 9 (2011): 394–401. http://dx.doi.org/10.17221/4143-pse.

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The phosphorus (P) availability was tested on hydromorphic soils located in theSavavalley. 480 soil profiles covering the area of31 227 hawas analysed in our study. The plant available P was determined by the Ammonium-Lactate method. The P availability in the surface layer (0&ndash;30 cm) is very low (up to 5 mg P2O5/100 g of soil) in about 30% of the tested agricultural land (9 440 ha), next 32% (9 897 ha) is in the range of a&nbsp;low P availability (from 5.1 to 10 mg), while only 17% (5 445 ha) has a&nbsp;good or very good P availability (above 20 mg). Especially high frequency

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9

Kovačević, V., I. Brkić, D. Šimić, G. Bukvić, and M. Rastija. "The role of genotypes on phosphorus, zinc, manganese and iron status and their relations in leaves of maize on hydromorphic soil." Plant, Soil and Environment 50, No. 12 (2011): 535–39. http://dx.doi.org/10.17221/4070-pse.

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Hydromorphy is a major soil fertility constraint in Europe and North America causing specific nutritional imbalance in soils and crops. The objectives of this study were to examine the differences among maize hybrids in phosphorus (P), zinc (Zn), manganese (Mn) and iron (Fe) status in leaves, and to investigate the interrelationship among these micronutrients as well as the interrelationship between Zn and P on hydromorphic soil in Eastern Croatia. Twenty maize (Zea mays L.) hybrids were grown under field conditions of Eastern Croatia in a period of two years. Considerable differences in mean

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10

Angst, Martin S., David R. Drover, Jörn Lötsch, et al. "Pharmacodynamics of Orally Administered Sustained- release Hydromorphone in Humans." Anesthesiology 94, no. 1 (2001): 63–73. http://dx.doi.org/10.1097/00000542-200101000-00014.

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Background The disposition kinetics of hydromorphone generally necessitates oral administration every 4 h of the conventional immediate-release tablet to provide sustained pain relief. This trial examined time course and magnitude of analgesia to experimental pain after administration of sustained-release hydromorphone as compared with that after immediate-release hydromorphone or placebo. Methods Using a 4 x 4 Latin square double-blind design, 12 subjects were randomized to receive a single dose of 8, 16, and 32 mg sustained-release hydromorphone and placebo. The same subjects had received 8

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11

Levy-Cooperman, PhD, Naama, Kerri A. Schoedel, PhD, Joseph L. Reiz, BSc, et al. "Abuse deterrence testing: A dose ratio escalation study examining naloxone coadministered with intravenous hydromorphone in non-treatment-seeking, opioid-dependent drug users." Journal of Opioid Management 12, no. 3 (2016): 165. http://dx.doi.org/10.5055/jom.2016.0329.

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Objective: To assess the reduction in intravenous (IV) abuse potential of hydromorphone from different dose ratio combinations with naloxone in opioid-dependent drug users.Design: Randomized, blinded, dose ratio escalation study.Setting: Single center.Participants: Following conversion to a stable IV dose of hydromorphone, 12 non-treatment-seeking, opioid-dependent subjects were randomly assigned and received at least one dose of study drug; seven subjects received all five study treatments. Five subjects withdrew early from the treatment phase: adverse events (2) and participant decision (3).

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&NA;. "Hydromorphone." Reactions Weekly &NA;, no. 1201 (2008): 17. http://dx.doi.org/10.2165/00128415-200812010-00049.

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&NA;. "Hydromorphone." Reactions Weekly &NA;, no. 1205 (2008): 15. http://dx.doi.org/10.2165/00128415-200812050-00041.

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&NA;. "Hydromorphone." Reactions Weekly &NA;, no. 1264 (2009): 20. http://dx.doi.org/10.2165/00128415-200912640-00060.

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&NA;. "Hydromorphone." Reactions Weekly &NA;, no. 432 (1992): 11. http://dx.doi.org/10.2165/00128415-199204320-00059.

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&NA;. "Hydromorphone." Reactions Weekly &NA;, no. 1228 (2008): 21. http://dx.doi.org/10.2165/00128415-200812280-00059.

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&NA;. "Hydromorphone." Reactions Weekly &NA;, no. 1246 (2009): 22. http://dx.doi.org/10.2165/00128415-200912460-00063.

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18

Murray, Alison, and Neil A. Hagen. "Hydromorphone." Journal of Pain and Symptom Management 29, no. 5 (2005): 57–66. http://dx.doi.org/10.1016/j.jpainsymman.2005.01.007.

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&NA;. "Hydromorphone." Reactions Weekly &NA;, no. 1360 (2011): 20. http://dx.doi.org/10.2165/00128415-201113600-00062.

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&NA;. "Hydromorphone." Reactions Weekly &NA;, no. 1123 (2006): 13. http://dx.doi.org/10.2165/00128415-200611230-00036.

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&NA;. "Hydromorphone." Reactions Weekly &NA;, no. 1128 (2006): 11–12. http://dx.doi.org/10.2165/00128415-200611280-00035.

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&NA;. "Hydromorphone." Reactions Weekly &NA;, no. 1157 (2007): 14. http://dx.doi.org/10.2165/00128415-200711570-00041.

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23

Myers, Debbie, and Rita A. Jung. "Hydromorphone." Journal of Exotic Pet Medicine 18, no. 1 (2009): 71–73. http://dx.doi.org/10.1053/j.jepm.2008.11.002.

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24

Pasero, Chris, and Margo McCaffery. "Hydromorphone." American Journal of Nursing 101, no. 2 (2001): 22–23. http://dx.doi.org/10.1097/00000446-200102000-00027.

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&NA;. "Hydromorphone." Reactions Weekly &NA;, no. 1346 (2011): 21. http://dx.doi.org/10.2165/00128415-201113460-00072.

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&NA;. "Hydromorphone." Reactions Weekly &NA;, no. 1398 (2012): 21. http://dx.doi.org/10.2165/00128415-201213980-00075.

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&NA;. "Hydromorphone." Reactions Weekly &NA;, no. 1411 (2012): 24. http://dx.doi.org/10.2165/00128415-201214110-00084.

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&NA;. "Hydromorphone." Reactions Weekly &NA;, no. 416 (1992): 9. http://dx.doi.org/10.2165/00128415-199204160-00035.

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&NA;. "Hydromorphone." Reactions Weekly &NA;, no. 410 (1992): 9. http://dx.doi.org/10.2165/00128415-199204100-00032.

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30

Kruglov, O., O. Menshov, V. Solovey, V. Lebed', and O. Andreeva. "CHERNOZEM SOIL GENETIC FEATURES DIAGNOSIS WITH MAGNETIC METHODS." Visnyk of Taras Shevchenko National University of Kyiv. Geology, no. 2 (89) (2020): 65–70. http://dx.doi.org/10.17721/1728-2713.89.09.

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The ecological-genetic status of soil is determined by the course of the soil-forming process and is the main factor in optimizing the agricultural use to achieve a sustainable state. The definition of a qualitative indicator of this status (KVAG) is developed in Ukraine and is characterized as costing and resource intensive. To solve the problem, it is proposed to replace agrochemical methods with less costly magnetic ones. The purpose of the study is to show the informativeness of geophysical methods for the indication of the process of pedogenesis on the example of chernozems podzolized of

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31

Ahn, Hyun Joo. "Synergistic Effect of Intravenous Ibuprofen and Hydromorphone for Postoperative Pain: Prospective Randomized Controlled Trial." July 2016 6;19, no. 6;7 (2016): 341–48. http://dx.doi.org/10.36076/ppj/2016.19.

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Background: An intravenous form of ibuprofen has recently been approved by the Food and Drug Administration (FDA) and reports are rare on its co-administration with opioids. Objectives: We researched whether an intravenous ibuprofen-hydromorphone combination is synergistic, additive, or infra-additive on postoperative pain. Study Design: A parallel-group, 1:1:1 allocation, randomized, double-blind controlled trial. Setting: University teaching hospital in Korea. Methods: Ninety patients, undergoing breast surgery, were divided into one of the 3 groups (I, H, IH groups). Positive analgesic effi

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32

Permitina, V. N. "Classification of the desert steppes ecosystems of Western Kazakhstan." Проблемы ботаники Южной Сибири и Монголии 19, no. 1 (2020): 151–55. http://dx.doi.org/10.14258/pbssm.2020030.

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The results of the steppe zone ecosystems investigation in Western Kazakhstan are presented. Theclassification of the main types of terrestrial ecosystems of the desert steppes subzone, divided by the forms of macrorelief(elevated plains, river valleys, sand massifs) and grouped into categories according to the type of water regime (automorphic,semihydromorphic, hydromorphic), is presented. Within the automorphic category, one zonal class of ecosystems hasbeen distinguished: cereal-wormwood desert steppes on light chestnut soils. The semi-hydromorphic category includesecosystems of wormwood-ha

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Novokhatin, Vasily, and Nadezhda Osipova. "Monitoring of agrophysical properties of the active layer of drained long-frozen peat deposits in Western Siberia." E3S Web of Conferences 164 (2020): 07016. http://dx.doi.org/10.1051/e3sconf/202016407016.

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In this study, the authors considered the dynamics of the main agrophysical properties of hydromorphic geosystems in Western Siberia. In the process of evolution, as well as in the conditions of technogenic impact, the soils of natural-territorial complexes, their properties are subject to significant changes. New hydromorphic geosystems are formed, the soils of which are characterized by changed agrophysical properties. Modern technologies for developing investment projects for soil reclamation of hydromorphic geosystems should be based on agrophysical characteristics of reclaimed soils, on t

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34

Gulur, Padma, Katharine Koury, Paul Arnstein, et al. "Morphine versus Hydromorphone: Does Choice of Opioid Influence Outcomes?" Pain Research and Treatment 2015 (November 1, 2015): 1–6. http://dx.doi.org/10.1155/2015/482081.

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Morphine has traditionally been considered the first line agent for analgesia in hospitals; however, in the last few years there has been a shift towards the use of hydromorphone as a first line agent. We conducted a hospital population based observational study to evaluate the increasing use of hydromorphone over morphine in both medical and surgical populations. Additionally, we assessed the effect of this trend on three key outcomes, including adverse events, length of stay, and readmission rates. We evaluated data from the University Health Systems Consortium. Data from 38 hospitals from O

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35

Westerling, D., H. Bjork, P. Svedman, and P. Hoglund. "Analgesic and Nonanalgesic Effects of Intravenous Hydromorphone - Relation to Plasma Concentrations in Healthy Volunteers." Pain Research and Management 1, no. 2 (1996): 86–92. http://dx.doi.org/10.1155/1996/313012.

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OBJECTIVE:To investigate the analgesic and nonanalgesic effects and the pharmacokinetics of an intravenous infusion of 2 mg hydromorphone over 20 mins.DESIGN:Open study.SUBJECTS:Twelve healthy volunteers.MEASUREMENTS:The analgesic effect of hydromorphone was evaluated serially using pressure pain thresholds (PPTs) measured on the third fingers and toes. The nonanalgesic effects of hydromorphone were measured as miosis, decrease of saliva production and central nervous effects such as euphoria/dysphoria, nausea, headache, fatigue and feeling of heaviness. Plasma concentration of hydromorphone w

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36

Coombs, Dennis W., Richard L. Saunders, Jonathan D. Fratkin, Lawrence E. Jensen, and Carol A. Murphy. "Continuous intrathecal hydromorphone and clonidine for intractable cancer pain." Journal of Neurosurgery 64, no. 6 (1986): 890–94. http://dx.doi.org/10.3171/jns.1986.64.6.0890.

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✓ The use of hydromorphone and clonidine, delivered intrathecally by an implanted infusion pump, is described in a patient with intractable cancer pain. The patient was a 48-year-old woman with uterine cervical cancer-related pain that was poorly responsive to conventional oral narcotics. Hydromorphone was used because of the patient's history of morphine intolerance. When progressive intrathecal hydromorphone dosages were required, intrathecal clonidine (an alpha2 adrenergic agonist) was infused concomitantly. Intrathecal hydromorphone and clonidine successfully controlled this patient's pain

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37

Song, Eun-Kee, Hyunjeong Shim, Hye-Suk Han, et al. "A Prospective Multicentre Study to Evaluate the Efficacy and Tolerability of Osmotic Release Oral System (Oros®) Hydromorphone in Opioid-Naive Cancer Patients: Results of the Korean South West Oncology Group Study." Pain Research and Management 20, no. 6 (2015): 293–99. http://dx.doi.org/10.1155/2015/458389.

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BACKGROUND: Osmotic release oral system (OROS®) hydromorphone is a potent, long-acting opioid analgesic, effective and safe for controlling cancer pain in patients who have received other strong opioids. To date, few studies have examined the efficacy of hydromorphone for pain relief in opioid-naive cancer patients.OBJECTIVES: A prospective, open-label, multicentre trial was conducted to determine the efficacy and tolerability of OROS hydromorphone as a single and front-line opioid therapy for patients experiencing moderate to severe cancer pain.METHODS: OROS hydromorphone was administered to

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38

Ershoff, Brent D., Tristan Grogan, Joe C. Hong, Pamela A. Chia, Eilon Gabel, and Maxime Cannesson. "Hydromorphone Unit Dose Affects Intraoperative Dosing." Anesthesiology 132, no. 5 (2020): 981–91. http://dx.doi.org/10.1097/aln.0000000000003176.

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Abstract Background Although clinical factors related to intraoperative opioid administration have been described, there is little research evaluating whether administration is influenced by drug formulation and, specifically, the unit dose of the drug. The authors hypothesized that the unit dose of hydromorphone is an independent determinant of the quantity of hydromorphone administered to patients intraoperatively. Methods This observational cohort study included 15,010 patients who received intraoperative hydromorphone as part of an anesthetic at the University of California, Los Angeles ho

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Fitzpatrick, RW, RM Taylor, U. Schwertmann, and CW Childs. "Occurrence and properties of lepidocrocite in some soils of New Zealand, South Africa and Australia." Soil Research 23, no. 4 (1985): 543. http://dx.doi.org/10.1071/sr9850543.

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Fifty-one samples, collected from 26 sites in New Zealand, South Africa and Australia, were tested for the presence of lepidocrocite (�-FeOOH) and goethite (�-FeOOH). The samples were predominantly orange-coloured mottles, bands, crusts and pipestems from hydromorphic soils, but also included a placic horizon, iron-rich precipitates from water courses, altered pyrite cubes, and geode-like features in weathered saprolites. The iron oxides were identified and characterized by X-ray diffraction (XRD) and transmission electron microscopy (TEM). Lepidocrocite was identified in 49 of the samples, an

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40

Sharma, Umakant, Rohini Khatri Olson, Federico Nicolas Erhart, et al. "Prescription Opioids induce Gut Dysbiosis and Exacerbate Colitis in a Murine Model of Inflammatory Bowel Disease." Journal of Crohn's and Colitis 14, no. 6 (2019): 801–17. http://dx.doi.org/10.1093/ecco-jcc/jjz188.

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Abstract Background and Aims Opioids are the most prescribed analgesics for pain in inflammatory bowel diseases [IBD]; however, the consequences of opioid use on IBD severity are not well defined. This is the first study investigating consequences of hydromorphone in both dextran sodium sulphate [DSS]-induced colitis and spontaneous colitis (IL-10 knockout [IL-10-/-]) mouse models of IBD. Methods To determine the consequences of opioids on IBD pathogenesis, wild-type [WT] mice were treated with clinically relevant doses of hydromorphone and colitis was induced via 3% DSS in drinking water for

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Shi, Jia, Shi-Han Du, Jian-Bo Yu, et al. "Hydromorphone Protects against CO2 Pneumoperitoneum-Induced Lung Injury via Heme Oxygenase-1-Regulated Mitochondrial Dynamics." Oxidative Medicine and Cellular Longevity 2021 (April 9, 2021): 1–19. http://dx.doi.org/10.1155/2021/9034376.

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Various pharmacological agents and protective methods have been shown to reverse pneumoperitoneum-related lung injury, but identifying the best strategy is challenging. Herein, we employed lung tissues and blood samples from C57BL/6 mice with pneumoperitoneum-induced lung injury and blood samples from patients who received laparoscopic gynecological surgery to investigate the therapeutic role of hydromorphone in pneumoperitoneum-induced lung injury along with the underlying mechanism. We found that pretreatment with hydromorphone alleviated lung injury in mice that underwent CO2 insufflation,

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Guenther, Sven, Travis C. Mickle, Andrew C. Barrett, et al. "Pharmacokinetics and Abuse Potential of Asalhydromorphone, a Novel Prodrug of Hydromorphone, After Intranasal Administration in Recreational Drug Users." Pain Medicine 21, no. 3 (2019): 511–20. http://dx.doi.org/10.1093/pm/pnz066.

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Abstract Objectives Hydromorphone (HM) is a potent μ-opioid receptor agonist with high susceptibility for abuse. A prodrug of hydromorphone, asalhydromorphone (ASAL-HM), has been designed to deter nonoral forms of abuse associated with hydromorphone. This study evaluated the intranasal (IN) pharmacokinetics and exploratory abuse potential of ASAL-HM compared with HM. Design Single-center, randomized, double-blind, crossover study. Setting Clinical research site. Subjects Healthy adult, nondependent recreational opioid users. Methods Subjects (N = 26) were randomized to receive IN administratio

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Wallace, MD, Mark, Dwight E. Moulin, MD, Richard L. Rauck, MD, et al. "Long-term safety, tolerability, and efficacy of OROS® hydromorphone in patients with chronic pain." Journal of Opioid Management 5, no. 2 (2018): 97. http://dx.doi.org/10.5055/jom.2009.0011.

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Objective: To assess the safety and efficacy of long-term repeated dosing of OROS® hydromorphone in chronic pain patients.Design: This multicenter, open-label extension trial enrolled patients from three short-term OROS® hydromorphone trials.Setting: Fifty-six centers in the United States and Canada.Patients: Adults with chronic cancer pain or chronic nonmalignant pain who were receiving stable doses of OROS® hydromorphone (≥8 mg/day). Three hundred and eighty-eight patients were enrolled, 106 patients completed at least 12 months of therapy.Interventions: OROS® hydromorphone (individualized d

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Rocha, Thiago Schmitz Marques da, Nereu Augusto Streck, Alencar Junior Zanon, et al. "Performance of soybean in hydromorphic and nonhydromorphic soil under irrigated or rainfed conditions." Pesquisa Agropecuária Brasileira 52, no. 5 (2017): 293–302. http://dx.doi.org/10.1590/s0100-204x2017000500002.

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Abstract: The objective of this work was to evaluate soybean cultivation in a hydromorphic or nonhydromorphic soil, with or without supplemental irrigation. Field experiments were carried out with the TECIRGA 6070RR and A 6411RG cultivars in highlands (nonhydromorphic soils) and lowlands (hydromorphic soils), which are traditionally cultivated with irrigated rice. The following parameters were determined in both soybean cultivars: leaf area index, developmental stages, dry matter partition, and leaf gas exchange. Low water stresses, which commonly occur either by deficit or excess in soybean a

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Sharpe, Emily E., Rochelle J. Molitor, Katherine W. Arendt, et al. "Intrathecal Morphine versus Intrathecal Hydromorphone for Analgesia after Cesarean Delivery." Anesthesiology 132, no. 6 (2020): 1382–91. http://dx.doi.org/10.1097/aln.0000000000003283.

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Abstract Background Intrathecal opioids are routinely administered during spinal anesthesia for postcesarean analgesia. The effectiveness of intrathecal morphine for postcesarean analgesia is well established, and the use of intrathecal hydromorphone is growing. No prospective studies have compared the effectiveness of equipotent doses of intrathecal morphine versus intrathecal hydromorphone as part of a multimodal analgesic regimen for postcesarean analgesia. The authors hypothesized that intrathecal morphine would result in superior analgesia compared with intrathecal hydromorphone 24 h afte

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Westerling, D., and P. Hoglund. "Concentration-Effect Relationship after Intravenous Hydromorphone Administration: Use of An Effect Compartment Model and System Analysis to Minimize Hysteresis of Effects." Pain Research and Management 2, no. 3 (1997): 167–72. http://dx.doi.org/10.1155/1997/161927.

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OBJECTIVE: To investigate the concentration-effect relationship of hydromorphone by using two different methods to minimize the hysteresis between concentration and effects.DESIGN: Open study.SUBJECTS: Twelve healthy volunteers.MEASUREMENTS: The analgesic effect of hydromorphone, evaluated as pressure pain thresholds (PPTs), and nonanalgesic effects, miosis and reduction of saliva production, were related to the concentration of the opioid, analyzed by high performance liquid chromatography. Hysteresis between the concentration and the measured effects of hydromorphone was minimized by a link

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Alon and Cachin. "Retardiertes Hydromorphon bei viszeralen, somatischen und neuropathischen Schmerzen." Praxis 99, no. 5 (2010): 283–91. http://dx.doi.org/10.1024/1661-8157/a000050.

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Ziel dieser multizentrischen longitudinalen Untersuchung war es, das Wirksamkeits- und Verträglichkeitsprofil von retardiertem Hydromorphon bei Patienten mit starken viszeralen, somatischen oder neuropathischen Schmerzen unter Praxisbedingungen zu dokumentieren. Dazu wurde eine prospektive Anwendungsbeobachtung in 57 Zentren mit insgesamt 196 Patienten in der Schweiz veranlasst. Nach durchschnittlich 43 Tagen der Behandlung mit retardiertem Hydromorphon nahm die Intensität der momentanen Schmerzen um 48.5% und die der maximalen Schmerzen um 41.3% ab, wobei die Wirksamkeit der Therapie bei visz

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Drover, David R., Martin S. Angst, Marta Valle, et al. "Input Characteristics and Bioavailability after Administration of Immediate and a New Extended-release Formulation of Hydromorphone in Healthy Volunteers." Anesthesiology 97, no. 4 (2002): 827–36. http://dx.doi.org/10.1097/00000542-200210000-00013.

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Background To compare the pharmacokinetics of intravenous, oral immediate-release (IR), and oral extended-release (OROS ) formulations of hydromorphone. Methods In this randomized, six-session, crossover-design study, 12 subjects received hydromorphone 8-mg intravenous, 8-mg IR oral, and 8-, 16-, and 32-mg OROS formulations or placebo orally followed by plasma sampling for hydromorphone determination. Pharmacokinetic analysis was performed using NONMEM. Using the disposition of hydromorphone from the intravenous administration, deconvolution was used to estimate the input rate function (releas

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Choi, Hahnl, Sara Radparvar, Samuel L. Aitken, and Jerry Altshuler. "Analgosedation: The use of Fentanyl Compared to Hydromorphone." Journal of Critical Care Medicine 7, no. 3 (2021): 192–98. http://dx.doi.org/10.2478/jccm-2021-0026.

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Abstract Background: The 2018 Society of Critical Care Medicine guidelines on the “Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU” advocate for protocol-based analgosedation practices. There are limited data available to guide which analgesic to use. This study compares outcomes in patients who received continuous infusions of fentanyl or hydromorphone as sedative agents in the intensive care setting. Methods: This retrospective cohort study evaluated patients admitted into the medical intensive care unit, the surg

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&NA;. "Hydromorphone withdrawal." Reactions Weekly &NA;, no. 1205 (2008): 15. http://dx.doi.org/10.2165/00128415-200812050-00043.

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