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Journal articles on the topic 'Hydrophilic gums'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Nkemakolam Nwachukwu and Chisom Martha Ani. "Characterization of new hydrophilic polymers obtained from co-processed Detarium microcarpum seed gum with acacia, guar and tragacanth gums." GSC Biological and Pharmaceutical Sciences 27, no. 1 (2024): 082–93. http://dx.doi.org/10.30574/gscbps.2024.27.1.0108.

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This work was aimed at developing and characterizing new hydrophilic polymers obtained through co-processing of Detarium microcarpum seed gum (DMG) with acacia (ACG), guar (GGG) and tragacanth (TGG) gums respectively. The hydrophilic polymer obtained from the seed of Detarium microcarpum (DT) was co-processed with acacia, guar and tragacanth gums respectively in proportions of 5%DMG+95%ACG, 10%DMG+90%ACG, 15%DMG+85%ACG, and 20%DMG+80%ACG. Replicate co-processed powders of DMG+GGG and DMG+TGG were prepared. The co-processed powders were characterized for: densities (bulk density, tapped density

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Nkemakolam, Nwachukwu, and Martha Ani Chisom. "Characterization of new hydrophilic polymers obtained from co-processed Detarium microcarpum seed gum with acacia, guar and tragacanth gums." GSC Biological and Pharmaceutical Sciences 27, no. 1 (2024): 082–93. https://doi.org/10.5281/zenodo.11958137.

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This work was aimed at developing and characterizing new hydrophilic polymers obtained through co-processing of <em>Detarium microcarpum </em>seed gum (DMG) with acacia (ACG), guar (GGG) and tragacanth (TGG) gums respectively. The hydrophilic polymer obtained from the seed of <em>Detarium microcarpum </em>(DT) was co-processed with acacia, guar and tragacanth gums respectively in proportions of 5%DMG+95%ACG, 10%DMG+90%ACG, 15%DMG+85%ACG, and 20%DMG+80%ACG. Replicate co-processed powders of DMG+GGG and DMG+TGG were prepared. The co-processed powders were characterized for: d

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3

Bonsu, Martina Aduenimaa, Kwabena Ofori-Kwakye, Samuel Lugrie Kipo, Mariam El Boakye-Gyasi, and Mary-Ann Fosu. "Development of Oral Dissolvable Films of Diclofenac Sodium for Osteoarthritis Using Albizia and Khaya Gums as Hydrophilic Film Formers." Journal of Drug Delivery 2016 (May 30, 2016): 1–11. http://dx.doi.org/10.1155/2016/6459280.

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Oral dissolvable films (ODFs) of diclofenac sodium intended for osteoarthritis were prepared using Albizia and Khaya gums as hydrophilic film formers. The physicochemical properties of the gums were characterized and the gums were used to prepare diclofenac sodium ODFs (~50 mg/4 cm2 film) by solvent casting. The two gums showed satisfactory film forming properties. The physicomechanical properties, drug-excipient compatibility, and in vitro drug release of the films in phosphate buffer pH 6.8 were studied. Khaya gum had higher extraction yield, moisture content, insoluble matter and true densi

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Sharadanant, R., and K. Khan. "Effect of Hydrophilic Gums on Frozen Dough. I. Dough Quality." Cereal Chemistry Journal 80, no. 6 (2003): 764–72. http://dx.doi.org/10.1094/cchem.2003.80.6.764.

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Rama Rao, Tadikonda. "HYDROPHILIC MATRIX TABLETS AS ORAL CONTROLLED DRUG DELIVERY SYSTEMS IN 20TH CENTURY: A REVIEW." International Journal of Advanced Research 12, no. 08 (2024): 1372–93. http://dx.doi.org/10.21474/ijar01/19381.

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Matrix systems are easy to formulate compared to other controlled release dosage forms. The manufacture of matrix tablets involves the direct compression of blend of drug, retardant material and additives to form a tablet in which drug is embedded in a matrix core of the retardant. Alternatively, retardant-drug blends may be granulated prior to compression. Of the three classes of retardant material used to formulate matrix tablets, polymers that form hydrophilic matrices are attracting the attention of pharmaceutical technologists. These polymers include Methyl cellulose (MC), Hydroxy ethyl c

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Mangesh, Dagale* Dr. Nilesh Gorde Kartik Shinde Ashwini Karnakoti Prajwal Birajdar. "Current Trends and Challenges in Sustained-Release Tablet Formulations: A Comprehensive Review." International Journal of Scientific Research and Technology 2, no. 1 (2025): 266–76. https://doi.org/10.5281/zenodo.14678430.

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The development of sustained release (SR) matrix tablets has garnered significant attention in modern pharmaceutical research owing to their ability to maintain prolonged therapeutic action, improve patient compliance, and enhance drug bioavailability. Among various approaches for achieving sustained release, the use of natural gums as matrix-forming agents has emerged as a promising strategy due to their biocompatibility, biodegradability, non-toxicity, and economic viability. This review focuses on the formulation, evaluation, and applications of SR matrix tablets, with a special emphasis on

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7

Olorunsola, Emmanuel O., Partap G. Bhatia, Babajide A. Tytler, and Michael U. Adikwu. "Thermochemical Properties of Hydrophilic Polymers from Cashew and Khaya Exudates and Their Implications on Drug Delivery." Journal of Drug Delivery 2016 (November 20, 2016): 1–7. http://dx.doi.org/10.1155/2016/7496585.

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Characterization of a polymer is essential for determining its suitability for a particular purpose. Thermochemical properties of cashew gum (CSG) extracted from exudates of Anacardium occidentale L. and khaya gum (KYG) extracted from exudates of Khaya senegalensis were determined and compared with those of acacia gum BP (ACG). The polymers were subjected to different thermal and chemical analyses. Exudates of CSG contained higher amount of hydrophilic polymer. The pH of 2% w/v gum dispersions was in the order KYG < CSG < ACG. Calcium was the predominant ion in CSG while potassium was pr

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8

Stanciu, Ioana. "Rheology of Gums Used in the Food and Flour Industry for "Tortillas"." Oriental Journal Of Chemistry 38, no. 4 (2022): 936–39. http://dx.doi.org/10.13005/ojc/380414.

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Food gums are hydrophilic colloids, which due to their functional properties are used in the food industry. For non-Newtonian rubber solutions to these factors must be added the dependence between the shear stress and the shear rate. Experimental data were obtained with a Haake RV20 rotary viscometer with a con-plate system. The range of shear speeds for which the determinations were made was between 24 and 3177s-1, and the shear stresses between 2.2 and 116.9Pa.

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9

Sharadanant, R., and K. Khan. "Effect of Hydrophilic Gums on the Quality of Frozen Dough: II. Bread Characteristics." Cereal Chemistry Journal 80, no. 6 (2003): 773–80. http://dx.doi.org/10.1094/cchem.2003.80.6.773.

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10

Ansari, Zoha, and Sangeet Goomer. "Natural Gums and Carbohydrate-Based Polymers: Potential Encapsulants." Indo Global Journal of Pharmaceutical Sciences 12 (2022): 01–20. http://dx.doi.org/10.35652/igjps.2022.12001.

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Plants possess a wide range of bioactive compounds with established health benefits which are highly susceptible to degradation. The environmental dynamics such as high temperature, light, oxygen limits the shelf life and bioavailability of these compounds in food and drug formulations. Encapsulation serves as an effective way of preserving these sensitive compounds by enclosing them within a coating/wall material and hence improves their bioavailability and functional properties.Scope and Approach: The wall materials used for encapsulation also known as encapsulants act as physical barriers b

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11

Varshosaz, Jaleh, Naser Tavakoli, and Fatemeh Kheirolahi. "Use of hydrophilic natural gums in formulation of sustained-release matrix tablets of tramadol hydrochloride." AAPS PharmSciTech 7, no. 1 (2006): E168—E174. http://dx.doi.org/10.1208/pt070124.

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12

Prakash, Chandra, Ganesh Kumar Choudhary, and Vimla Chowdhary. "Development and Utilization of Newly Synthesized Tamarind-6-Amino Hexanoic Acid (TAMHA) Resin for Removal of Toxic Heavy Metals Ions from Industrial Effluents." Oriental Journal Of Chemistry 40, no. 2 (2024): 594–98. http://dx.doi.org/10.13005/ojc/400235.

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Tamarind Kernel Powder (TKP) and its biosorbents that went through chemical modification are crucial for removing heavy metals from industrial effluents including Fe2+, Cd2+, Pb2+, Cu2+, Zn2+. TKP is a natural polymer that is fully non-toxic, biocompatible, and biodegradable and belongs to the group of natural gums. It has a matrix made of hydrophilic polysaccharides, which has been utilized for the generating chelating resins. The chelating resin, based on tamarind kernel powder and containing a 6-Amino hexanoic acid, has been created in the current work. FTIR, TGA, SEM, ion exchange capacity

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13

Sharadanant, R., and K. Khan. "Effect of Hydrophilic Gums on the Quality of Frozen Dough: Electron Microscopy, Protein Solubility, and Electrophoresis Studies." Cereal Chemistry Journal 83, no. 4 (2006): 411–17. http://dx.doi.org/10.1094/cc-83-0411.

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14

Efimov, Konstantin V. "Study of the properties of water-swelling rubber containing gums and extelint." Butlerov Communications 62, no. 4 (2020): 72–76. http://dx.doi.org/10.37952/roi-jbc-01/20-62-4-72.

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It is known that the main role in water-swellable sealing elements belongs to rubber, the properties of which depend on the nature of the rubbers and functional ingredients used. Water-swellable sealing elements are mainly made from rubbers based on acrylate, chloroprene and nitrile butadiene rubbers using various hydrophilic additives: starch derivatives, cellulose, polyvinyl alcohol and various oligomeric resins. However, after sufficiently long contact with water, some additives are washed out and the sealing properties of the sealing elements are lost. Among the promising insoluble and lim

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15

Kalbhare, Shankar, Rohit K. Pawar, Vivekkumar K. Redasani, Amita B. Yadav, Vishal R. Mohite, and Vaibhav B. Kadam. "Role of Aminated Derivatives of Natural Gum in Release Modulating Matrix System of Losartan Potassium." International Journal of Pharmaceutical Sciences and Nanotechnology(IJPSN) 15, no. 6 (2022): 6204–15. http://dx.doi.org/10.37285/ijpsn.2022.15.6.3.

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Objective: The investigation aimed to synthesize amino derivatives of various natural gums like Xanthan gum and Tamarind gum for using them as a release modulating polymer in the formulation of the hydrophilic matrix system of losartan potassium and to find the best amongst them. Developing oral sustained release matrix tablets for a drug with a constant release rate has always been a challenge to the pharmaceutical technologist.  Materials and Methods: Release modulating hydrophilic matrix tablets of losartan potassium were prepared by wet granulation method. A total number of 6 formula

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Verma, Amit Kumar, Arun Kumar, Subbiah Ramasamy, Ajit Kumar Yadav, and Rohit Kumar Bijauliya. "Evaluation of Drug Release from Carboxymethyl Starch-Xanthan Gum-HPMC Matrix." Journal of Drug Delivery and Therapeutics 11, no. 5 (2021): 27–32. http://dx.doi.org/10.22270/jddt.v11i5.5000.

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The use of hydrophilic polymers from natural origin. Especially the polysaccharides have been the focus of current research activity in the design of matrix device due to their non toxic, biocompatible, biodegradable nature and broad regulatory acceptance. A large number of polysaccharides such as Carboxymethyl starch, Xanthan gum, Hydroxy propyl methyl cellulose (HPMC), Sodium Alginate etc, have been used as hydrophilic matrices to investigate release behavior of drug. In order to enrich the resources, there is a quest for new polysaccharide owing to their diverse chemical composition and fun

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17

Gaurav, Bhardwaj, Tak Kapil, Tanwar Y.S., Rathore R.P.S., and Choudhary Kuldeep. "Development and Evaluation of Extended Release Matrix Tablet of Metoprolol Succinate." Pharmaceutical and Chemical Journal 2, no. 3 (2015): 47–53. https://doi.org/10.5281/zenodo.13730216.

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The objective of this study was to design and evaluate oral sustained drug delivery system for metoprolol succinate using hydrophilic polymers such as HPMC K4M and HPMC K100M batches. Four batches were prepared by using HPMC K4M in drug: polymer ratio of 1:1, 1:1.5, 1:2, 1:3 and five batches using HPMC K100M in ratios of 1:1, 1:1.25, 1:1.5, 1:1.75, 1:2. Further formulation F9 was modified by varying the ratios of diluents i.e. F10, F11, F12, F13 to check the effect of diluents on drug release. Matrix tablets were prepared by wet granulation method and were evaluated for weight variation, conte

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18

Sunil Kumar P, Dhanwantari Naidu, Padmanabhan P, and Paul T Joyes. "Modified dosage evaluation of continued release of DiDomenico sodium tablets by means of hydrophilic polymer blends." International Journal of Research in Pharmaceutical Sciences 11, SPL4 (2020): 315–22. http://dx.doi.org/10.26452/ijrps.v11ispl4.3797.

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That term altered - discharge measurement manifestation is used to portray results that change the timing and rate for the arrival of the drug substance. A modified release measurement type will be characterized "as a particular case to which the pill arrival aspects for a period course or area need aid picked on finish restorative alternately comfort destinations not advertised by routine measurement structures, for example, solutions, ointments, alternately immediately dissolving dosages manifestations. xanthan gum, a polysaccharide, crude cashew gum, Diclofenac sodium powder, hydroxypropyl

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Bahú, Juliana O., Lucas R. Melo de Andrade, Raquel de Melo Barbosa, et al. "Plant Polysaccharides in Engineered Pharmaceutical Gels." Bioengineering 9, no. 8 (2022): 376. http://dx.doi.org/10.3390/bioengineering9080376.

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Hydrogels are a great ally in the pharmaceutical and biomedical areas. They have a three-dimensional polymeric structure that allows the swelling of aqueous fluids, acting as an absorbent, or encapsulating bioactive agents for controlled drug release. Interestingly, plants are a source of biogels, specifically polysaccharides, composed of sugar monomers. The crosslinking of these polymeric chains forms an architecture similar to the extracellular matrix, enhancing the biocompatibility of such materials. Moreover, the rich hydroxyl monomers promote a hydrophilic behavior for these plant-derived

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20

Souza, Felipe Menezes de, Juliana Mikaelly Dias Soares, Helinando Pequeno de Oliveira, Isabel Cristina Rigoli, and Samuel Luporini. "Evaluation of hydrophylic montmorillonite nanofluids and xantane gum in saline environment." Research, Society and Development 9, no. 8 (2020): e75985305. http://dx.doi.org/10.33448/rsd-v9i8.5305.

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With an estimated increasing oil demand in the coming decades, the need to explore non-applicable areas is intensified, and associated with them, before the high exploration costs, the need to improve available technologies. In this sense, in the last decade, the application of nanoparticles to improve drilling fluids has been intensified. In this scenario, montmorillonite nanoclays and xanthan gums were little explored for the development of nanofluids. In this work, the influence of hydrophilic nanoclay on the rheological parameters of xanthan, sodium and calcium chlorides solutions was veri

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Reolon, Jéssica Brandão, Camila Parcianello Saccol, Bárbara Felin Osmari, et al. "Karaya/Gellan-Gum-Based Bilayer Films Containing 3,3′-Diindolylmethane-Loaded Nanocapsules: A Promising Alternative to Melanoma Topical Treatment." Pharmaceutics 15, no. 9 (2023): 2234. http://dx.doi.org/10.3390/pharmaceutics15092234.

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This study aimed to incorporate nanocapsules containing 3,3′-diindolylmethane (DIM) with antitumor activity into a bilayer film of karaya and gellan gums for use in topical melanoma therapy. Nanocarriers and films were prepared by interfacial deposition of the preformed polymer and solvent casting methods, respectively. Incorporating DIM into nanocapsules increased its antitumor potential against human melanoma cells (A-375) (IC50 > 24.00 µg/mL free DIM × 2.89 µg/mL nanocapsules). The films were transparent, hydrophilic (θ < 90°), had homogeneous thickness and weight, and had a DIM conte

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Porto, Michele, Paolino Caputo, Valeria Loise, Giovanni De Filpo, Cesare Oliviero Rossi, and Pietro Calandra. "Polysaccharides-Reinforced Bitumens: Specificities and Universality of Rheological Behavior." Applied Sciences 9, no. 24 (2019): 5564. http://dx.doi.org/10.3390/app9245564.

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The rheological properties of bitumens can be modified by the addition of specific chemical additives. Taking into account the molecular complex aggregation pattern, we hypothesized that macromolecules characterized by long, flexible, and hydrophilic chains can establish soft bridges connecting the different polar aggregates of asphaltenes, strengthening their overall hierarchical supra-structures, and consequently increasing rheological performance at higher temperatures. Here, we propose the use of low cost and high availability polysaccharides as chemical additives to improve the rheologica

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23

Sreenivasa, Reddy N. Mahendra Kumar CB Ramesh A. "FORMULATION OF GASTRO RETENTIVE MATRIX TABLETS FOR ANTIHYPERTENSIVE DRUGS USING NATURAL GUMS AND LOW-DENSITY POLYMERS: EFFECT OF FORMULATION FACTORS ON IN VITRO DISSOLUTION RATES." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 04 (2019): 8346–60. https://doi.org/10.5281/zenodo.2650760.

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<em>The objective of the study was to develop Gastro retentive matrix tablets for antihypertensive drugs. The matrix tablets of antihypertensive drug captopril with 12 formulations coded as F1 to F12 with variant ratios of polymer were prepared in the preliminary studies by direct compression method. Hydrophilic and hydrophobic low density polymers like HPMC M15K and HPMC M4K and natural gums like Karaya gum, Xanthan gum, Pullulan gum, Gellan gum and Guar gum were used. The pre-compression parameters, and compatibility of drug with various excipient was studied using HPTLC, FTIR and DSC. The t

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Jange, Camila, Rhonda Graef, Chad Penn, Carl Wassgren, and Kingsly Ambrose. "Controlling Nutrient Leaching Profile of Urea Granules through Structural Modification." Journal of the ASABE 66, no. 6 (2023): 1415–24. http://dx.doi.org/10.13031/ja.15675.

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Highlights Effect of granule microstructure, formulation design on nutrient leaching was investigated. Reduction in nutrient leaching was observed in denser core granules with binder compared to low density granules. The power-law model overpredicted the inorganic dissolved nitrogen content. Abstract. Ammonium and nitrate are byproducts of urea fertilizer hydrolysis in soil. Ammonium is highly unstable and can volatilize in the form of ammonia, a greenhouse gas. Meanwhile, nitrate is highly hydrophilic and can contaminate surface and groundwater systems. This study investigated the influence o

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Tosif, Mansuri M., Agnieszka Najda, Aarti Bains, Grażyna Zawiślak, Grzegorz Maj, and Prince Chawla. "Starch–Mucilage Composite Films: An Inclusive on Physicochemical and Biological Perspective." Polymers 13, no. 16 (2021): 2588. http://dx.doi.org/10.3390/polym13162588.

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In recent years, scientists have focused on research to replace petroleum-based components plastics, in an eco-friendly and cost-effective manner, with plant-derived biopolymers offering suitable mechanical properties. Moreover, due to high environmental pollution, global warming, and the foreseen shortage of oil supplies, the quest for the formulation of biobased, non-toxic, biocompatible, and biodegradable polymer films is still emerging. Several biopolymers from varied natural resources such as starch, cellulose, gums, agar, milk, cereal, and legume proteins have been used as eco-friendly p

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Mohammad Ali Khan, Sumraiz Ammen, Ali Zia, et al. "Extraction, formulation and evaluation of fast dissolving oral films of nicotine for smoking cessation." Journal of Contemporary Pharmacy 2, no. 1 (2018): 1–6. http://dx.doi.org/10.56770/jcp201801.

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To produce oral films of nicotine in a laboratory setting to aid smokers in smoking cessation. Nicotine is a highly addictive drug and many people suffer from its addiction around the globe in the form of smoking. This problem is particularly pronounced in Pakistan and many smokers here do not have access to cessation medications. To prevent smokers from inhaling harmful chemicals like tar, carbon mono oxide and carcinogenic compounds produced from burning vegetable matter, pharmaceutical nicotine is used in the form of chewing gums, TDDS patches and oral films. The oral route is one of the mo

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ASGHAR, Ali, Faqir Muhammad ANJUM, Masood Sadiq BUTT, Muhammad Waseem TARIQ, and Shahzad HUSSAIN. "Rheological and Storage Effect of Hydrophillic Gums on the Quality of Frozen Dough Pizza." Food Science and Technology Research 13, no. 2 (2007): 96–102. http://dx.doi.org/10.3136/fstr.13.96.

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28

Vaishnavi, Bandari, G. Tarun Reddy, Akash Bansal, Deva Likitha, Deeksha Charagondla, and D. Prasanthi. "Solubility Enhancement of Efinaconazole using Neem Gum and Evaluation of Antifungal Activity." Indian Journal Of Science And Technology 17, no. 17 (2024): 1735–44. http://dx.doi.org/10.17485/ijst/v17i17.311.

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Objectives: Efinaconazole is an anti-fungal drug of BCS class II used for treating Onchomycosis. Neem gum known for its antifungal properties was purified and used as hydrophilic carrier. Solid dispersions by physical mixture and solvent evaporation method were prepared using purified Neem gum. Methods: The prepared solid dispersions in ratios 1:1, 1:3 and 1:6 were characterized for percentage yield, assay, solubility, and dissolution studies. The optimized solid dispersion SD6 was formulated as gel for ease of application. Gels were characterized for physico-chemical properties and in-vitro d

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Heyam, Saad Ali, Saad Rasha, M. A. Elhaj Babiker, Khan Jiyauddin, Kaleemullah Mohammed, and Al-Dhalli Samer. "Effect of Different Parameters on the Release of Diclofenac Modified Tablets." International Journal of Current Pharmaceutical Review and Research 8, no. 2 (2017): 192–97. https://doi.org/10.5281/zenodo.12677968.

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In the present study the influence of designing and development of sustained release (SR) matrix tablets of diclofenacsodium were investigated. The aim was to increase therapeutic efficacy, reduce frequency of administration, and improvepatient compliance. Sustained release matrix tablets of diclofenac sodium, were developed by using different drug: gumratios, using Xanthan gum as matrix former, microcrystalline cellulose as diluent and Polyethylene Glycol (PEG 6000) asrelease modifier. Formulated tablets were evaluated for friability, hardness, thickness and their relation to the amount ofgum

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MOUSSAOUI-KHEDAM, Nassima, Fatima BENNEDJAR, Khadidja YANALLAH, et al. "Formulation and evaluation of W1/O/W2 topic double emulsions containing essential oils, cafeine and various hydrocolloids." AJHS 4, no. 1 (2022): X. https://doi.org/10.5281/zenodo.6482970.

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<strong>Introduction:</strong> Double emulsions are complex dispersed systems thermodynamically unstable; are therefore subject to various phenomena of instability, such as the swelling of internal droplets under the effect of osmotic pressure, flocculation and coalescence of oily globules or coalescence of internal water droplets.  The objective of this study was to formulate a cosmetic treatment in the form of a stable Hydrophilic/Lipophilic/Hydrophilic double emulsion, containing active substances with anti-cellulite, restorative and regenerating properties; these substances

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Bandari, Vaishnavi, Tarun Reddy G, Bansal Akash, Likitha Deva, Charagondla Deeksha, and Prasanthi D. "Solubility Enhancement of Efinaconazole using Neem Gum and Evaluation of Antifungal Activity." Indian Journal of Science and Technology 17, no. 17 (2024): 1735–44. https://doi.org/10.17485/IJST/v17i17.311.

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Abstract <strong>Objectives:</strong> Efinaconazole is an anti-fungal drug of BCS class II used for treating Onchomycosis. Neem gum known for its antifungal properties was purified and used as hydrophilic carrier. Solid dispersions by physical mixture and solvent evaporation method were prepared using purified Neem gum. <strong>Methods:</strong> The prepared solid dispersions in ratios 1:1, 1:3 and 1:6 were characterized for percentage yield, assay, solubility, and dissolution studies. The optimized solid dispersion SD6 was formulated as gel for ease of application. Gels were ch

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Subhajit, Roy* Mayukh Jana Amlan Bishal Anwesha Adak. "Formulation and Development of Metformin Sustained Release Tablets by Hydrophilic Polymer." International Journal in Pharmaceutical Sciences 1, no. 9 (2023): 129–39. https://doi.org/10.5281/zenodo.8330636.

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Metformin HCL, the only biguanide still in use today, reduces peripheral insulin resistance and hepatic glucose production in people with Type 2 diabetes. It has a short plasma half-life and a low absolute bioavailability. The primary goal of this study was to create an oral sustained release metformin tablet employing the direct compression technique and rate-controlling ingredients like hydrophilic hydroxypropyl methylcellulose and Xanthan gum polymer. Thickness, weight fluctuation, hardness, consistency of drug content, and in vitro drug release were all assessed for all batches. The term &

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Djebbar, Mohamed, Nacéra Chaffai, Fatiha Bouchal, and Noureddine Aouf. "Effervescent floating tablets of metformin HCl developed by melt granulation. Part I: Effect of hydrophilic polymer on biopharmaceutical properties." GSC Biological and Pharmaceutical Sciences 6, no. 2 (2019): 052–67. https://doi.org/10.5281/zenodo.4303950.

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In the present study which the aim to evaluate the effect of hydrophilic polymer on the biopharmaceutical properties of metformin hydrochloride floating tablets, we have prepared floating systems using melt granulation, according to effervescent approach. Two hydrophilic polymers are used at various concentrations (10, 12.5, 15 and 17.5%), Acacia gum and hydroxypropylmethylcellulose (HPMC) at three viscosity grades (K4M, K15M and K100M). In addition to the satisfactory physical parameters, the evaluation of buoyancy and <em>in vitro</em> dissolution of floating developed systems reve

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Abdullah, KURT. "SYNTHESIS, CHARACTERIZATION, AND RHEOLOGICAL PROPERTIES OF MODIFIED XANTHAN GUM." INTERNATIONAL JOURNAL OF CURRENT NATURALSCIENCE AND ADVANCE PHYTOCHEMISTRY 1, no. 1/1 (2021): 1–11. https://doi.org/10.5281/zenodo.5809415.

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Xanthan gum (XG) is a microbial exo-polysaccharide (biocompatible, biodegradable, and hydrophilic) produced industrially from the fermentation of simple carbon sources under aerobic conditions by Gram-negative bacteria Xanthomonas campestris. As a great commercial significance, it has demonstrated interesting properties like biodegradability, high viscosity at a low shear rate and stability under a wide range of temperature and pH which leads to the wide range of applications such as pharmaceutical, cosmetic, biomedical, petroleum and agriculture, especially in food applications. However, cert

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Darekar, A. B., S. M. Sonawane, and R. B. Saudagar. "Formulation and Evaluation of Orally Fast Dissolving Wafer by Using Natural Gum: Review Article." International Journal of Current Pharmaceutical Review and Research 9, no. 3 (2017): 253–60. https://doi.org/10.5281/zenodo.12674551.

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Oral thin film a new drug delivery system for the oral delivery of the drugs, was developed based on the technology of thetransdermal patch. Fast-dissolving oral thin film is a solid dosage form, which disintegrate or dissolve within 1 min whenplaced in the mouth without drinking water or chewing. Oral film includes various ingredients for its formulation. Fastdissolving film is prepared using hydrophilic polymers that rapidly dissolves on the tongue or buccal cavity, delivering thedrugto the systemic circulation via dissolution when contact with liquid is made. Water-soluble polymers are used

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Darekar, A. B., S. M. Sonawane, and R. B. Saudagar. "Formulation and Evaluation of Orally Fast Dissolving Wafer by Using Natural Gum: Review Article." International Journal of Current Pharmaceutical Review and Research 8, no. 3 (2024): 253–60. https://doi.org/10.5281/zenodo.12677573.

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Oral thin film a new drug delivery system for the oral delivery of the drugs, was developed based on the technology of thetransdermal patch. Fast-dissolving oral thin film is a solid dosage form, which disintegrate or dissolve within 1 min whenplaced in the mouth without drinking water or chewing. Oral film includes various ingredients for its formulation. Fastdissolving film is prepared using hydrophilic polymers that rapidly dissolves on the tongue or buccal cavity, delivering thedrugto the systemic circulation via dissolution when contact with liquid is made. Water-soluble polymers are used

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Amwaj, Abdullah Altowairqi, Mohammed Baghdadi Afra, and Thabet Elsharawy Nagwa. "Hydrocolloids is a new trend as meat preservative." World Journal of Biology Pharmacy and Health Sciences 9, no. 3 (2022): 020–29. https://doi.org/10.5281/zenodo.6404342.

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Meat eating aids in the absorption of proteins and vital amino acids, as well as vitamins and minerals such as vitamin B, vitamin A, zinc, and iron, all of which are required for a balanced diet. This evaluation looked into the many types of hydrocolloids and whether they may be used as a new, safe natural meat preservative. Natural, semi-synthetic, and synthetic hydrocolloids are classified according to their origin. Hydrophilic polymers generated from natural sources such as plants, animals, microbes, and seaweeds are known as natural hydrocolloids. Semi-synthetic hydrocolloids, on the other

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Subba, Reddy K.V, and G. Simhachalam. "Dietary Aqua Fix Effectively Alters the Qualitative Protein Profile in the Head Kidney." Biolife 10, no. 4 (2022): 16–21. https://doi.org/10.5281/zenodo.7286178.

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<strong>Abstract</strong> The qualitative protein profile in head kidney of 6, 9 and 12 months old <em>Labeo rohita</em> was investigated by feeding with a diet mixed with an immunomodulator, Aqua Fix. 6 (group A), 9 (group B), and 12 (group C) months old fish (12-15 g wt.; 12 fish in each group) were fed with a diet mixed with Aqua Fix @ 50 mg/100 g of feed for 4 days.  Another 3 groups (a, 6 months; b, 9 months; and c, 12 months) of same weight (12 fish in each group) were fed with a normal diet to act as controls for comparison.  Head kidney showed significant alteration (with low

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Tetiana, Popova, Kukhtenko Halyna, Bevz Nataliia, and Kukhtenko Oleksandr. "Biopharmaceutical and rheometric studies in the development of a gel composition with dimethindene maleate." ScienceRise: Pharmaceutical Science, no. 3(31) (June 30, 2021): 11–18. https://doi.org/10.15587/2519-4852.2021.234250.

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Every year there is an increase in the number of cases of hypersensitivity to bites from various insects. A local allergic reaction to bites occurs within a few minutes and is accompanied by acute pain at the site of the bite, severe itching, hyperemia, the appearance of papules, tissue edema, and sometimes a small-point rash around. Considering the small number of drugs for local therapy of allergic manifestations and the unidirectional nature of their action, it is urgent to develop a drug containing the antihistamine dimethindene maleate and dexpanthenol, which plays the role of an anti-inf

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Asghar, Ali, Faqir Muhammad Anjum, Masood Sadiq Butt, and Shahzad Hussain. "Shelf Life and Stability Study of Frozen Dough Bread by the Use of Different Hydrophillic Gums." International Journal of Food Engineering 2, no. 3 (2006). http://dx.doi.org/10.2202/1556-3758.1040.

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The main objective of this work was to determine the influence of different hydrophilic gums on the stability and shelf life of bread dough during frozen storage. Bread dough containing different level of hydrophilic guns were submitted to mechanical freezing at -18° C and stored frozen for up to 60 days. Two types of hydrophilic gums in different combination were tested: for specific loaf volume of breads made from frozen dough and for its shelf life study by measuring its moisture level at 3, 24, 48, 72 and 96 hrs after baking of frozen dough bread. Specific loaf volume was significantly aff

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Crowe-White, Kristi M., Seung Eun Jung, Anna Bragg, and Katelyn E. Senkus. "Functional sugar-free chewing gum infused with spices bolsters antioxidant capacity and phenolic content of saliva." Scientific Reports 13, no. 1 (2023). http://dx.doi.org/10.1038/s41598-023-30931-2.

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AbstractOral and vascular diseases are seemingly disparate conditions, yet individuals with poor oral health are at increased risk for cardiovascular events. Spice-derived bioactive polyphenols with antioxidant functionality may attenuate mechanisms linking the diseases, namely oxidative stress and inflammation. Acknowledging that novel approaches to increase antioxidant intake are warranted, the purpose of this study was to evaluate the influence of two functional sugar-free gums infused with spices on antioxidant capacity and phenolic content of saliva using the oxygen radical absorbance cap

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Qi, Yan, Junbiao Peng, Chunsheng Zhang, Danling Wang, Yihu Song, and Qiang Zheng. "Impact of an oligomer deep eutectic solvent on structure and properties of natural rubber vulcanizates and their nanocomposites." Journal of Applied Polymer Science, July 23, 2024. http://dx.doi.org/10.1002/app.56006.

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AbstractRubber nanocomposites exhibit strain softening under large‐amplitude oscillation shear and large‐strain cyclic tension while the softening behaviors are hard to regulate in industry. Herein, an oligomer deep eutectic solvent (DES) synthesized from polyethyleneglycol and tetrabutylammonium bromide is used to mediate the vulcanization and softening behaviors of natural rubber (NR) gums and their nanocomposites. The results show that DES could accelerate NR vulcanization and improve crosslinking density. For the hydrophilic silica nanocomposites, DES could greatly reduce tanδ and weaken w

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Shiam, Md Azizul Hakim, Mst Sadia Islam, Iftakhar Ahmad, and Sumaiya Sadia Haque. "A review of plant-derived gums and mucilages: Structural chemistry, film forming properties and application." Journal of Plastic Film & Sheeting, January 27, 2025. https://doi.org/10.1177/87560879251316553.

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Plant-based gums and mucilages are versatile biopolymers with significant industrial, environmental, and biological applications. Derived from various plant sources such as seeds, roots, leaves, and exudates, these polysaccharides comprise proteins, bioactive substances, and neutral sugars like arabinose, galactose, and galacturonic acid. Their unique structural and functional properties, such as high viscosity, water retention, and heat stability, make them valuable in the food, pharmaceutical, and cosmetic industries. Due to their hydrophilic nature and ability to form hydrogen bonds with wa

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Malviya, Rishabha, Vandana Tyagi, and Dharmendra Singh. "Techniques of Mucilage and Gum Modification and their Effect on Hydrophilicity and Drug Release." Recent Patents on Drug Delivery & Formulation 14 (December 4, 2020). http://dx.doi.org/10.2174/1872211314666201204160641.

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Aim: The manuscript aims to describe the techniques of modification of gums and mucilages and their effect on hydrophilicity and drug release. Discussion: The interest is increased in the fields of polymers which is obtained from natural origin and used in the preparation of pharmaceuticals. Mucilage and gum are natural materials, widely used in the preparation of novel dosage form and conventional dosage form. They are used in the pharmaceutical industry for various purposes like suspending, emulsifying, bio-adhesive, binding, matrix-forming, extended release and controlled release agent. Gum

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Ugoeze, Kenneth Chinedu, and Bethel Covenant Ameh. "Studies of Co-Processed Hydrophilic Polymer Composites of Cissus Gum with Acacia, Tragacanth or Guar Gums: Processing and Characterization." Advances in Image and Video Processing 9, no. 2 (2021). http://dx.doi.org/10.14738/aivp.92.9939.

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Rahul Laxman Jadhav, Manisha Vyankatrao Patil, and Shaikh Siraj N. "Synthesis, Characterization and Invivo Evaluation of Poly Sulfoxy Amine Grafted Xanthan Gum." International Journal of Life Science and Pharma Research, June 22, 2022, 20–28. http://dx.doi.org/10.22376/ijpbs/lpr.2020.10.3.p20-28.

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Natural polymers are hydrophilic in nature, economic, chemically inert, easily available, biodegradable, and non-toxic. Following problems associated with the use of gums include uncontrolled rates of hydration, pH dependent solubility, thickening, drop in viscosity on storage, and the possibility of microbial contamination. Chemical modification of gums not only minimizes these drawbacks but also alter their physicochemical properties. Recently, researchers have been modifying properties of natural gums to explore its more applicability. Aim of the current study was to explore Xanthan gum’s a

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Kumar, V. Vijaya, B. Deekshi Gladiola, C. Madhusudhana Chetty, and R. E. Ugandar. "FORMULATION AND EVALUATION OF GASTRO RETENTIVE DRUG DELIVERY SYSTEM OF ZANAMIVIR USING DIFFERENT POLYMERS." Journal of Biomedical and Pharmaceutical Research 8, no. 4 (2019). http://dx.doi.org/10.32553/jbpr.v8i4.641.

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The objective of the present study is to develop gastro retentive drug delivery system of Zanamivir .Floating tablets of Zanamivir were developed with a gas generating agent NaHCO3 and in combination of different hydrophobic and hydrophilic polymers like xanthan gum, guar gum, HPMC and methyl cellulose .In the present work attempts have been made to prepare six formulations of Zanamivir in different ratios of drug and polymer to get a desired release profile by direct compression method .All the prepared tablets were evaluated in terms of pre compression and post compression parameters. FTIR s

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Shakouri, Shahrzad, Mostafa Mazaheri Tehrani, Arash Koocheki, Reza Farhoosh, Anna Abdolshahi, and Nabi Shariatifar. "Bigels as Novel Drug Delivery Systems: A Systematic Review on Efficiency and Influential Factors." Current Reviews in Clinical and Experimental Pharmacology 20 (October 30, 2024). http://dx.doi.org/10.2174/0127724328288796240906040927.

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Background: Bigles are novel formulation merging two phase of hydrogel and organogel revealing dual properties to release active agents based on their lipophilic or hydrophilic nature. Methods: A systematic search was conducted in PubMed, Scopus, and ISI Web of Science to find eligible studies evaluating the efficiency of bigels in drug release. 20 articles were included in the analysis based on the defined criteria. Results: The results indicated that several different natural materials were used for bigel making. Span (52.38%) and Sunflower oil (23.80%) were the most solvents used for organo

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Ahmed, Walaa, Riham I. El-Gogary, Maha Nasr, and Omaima A. Sammour. "Development and in Vitro/In Vivo Evaluation of Itopride Hydrochloride Expanding Tablets." Journal of Pharmaceutical Innovation, April 13, 2023. http://dx.doi.org/10.1007/s12247-023-09729-2.

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Abstract Purpose Gastroretentive drug delivery systems (GRDDS) have attracted interest for enhancement of absorption and bioavailability of some drugs. Itopride hydrochloride (ITOP) is a drug used for treatment of gastroesophageal reflux and other gastric motility disorders, but is characterized by narrow absorption window and short in vivo half-life. Therefore, it is expected that its formulation in expanding gastroretentive tablets would increase its gastric residence, thus leading to decreased frequency of administration and increased patient compliance. Methods The direct compression metho

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Asamoa Mensa, Kofi Acheampong, Noble Kuntworbe, Yaa Asantewaa Osei, et al. "Physicochemical and Emulsifying Properties of Melia azedarach Gum." Scientifica 2024, no. 1 (2024). http://dx.doi.org/10.1155/2024/3308441.

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Naturally occurring hydrophilic colloids are versatile excipients in drug delivery systems. They are often used as coating materials, disintegrating agents, binders, emulsion stabilizers, and other applications. This study sought to investigate the physicochemical and emulsifying properties of gum extracted from Melia azedarach (MA). The gum was harvested, authenticated, and purified using ethanol precipitation. Physicochemical, microbial, and proximate analyses were performed on the purified gum. Oil of olive emulsions containing different amounts (5–15%w/v) of the gum as emulsifiers were pre

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