Relevant bibliographies by topics / Hydroxy coumarin

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Hydroxy coumarin'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Hydroxy coumarin"

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Nagaretnam, Prahadeesh, and Arulmoly Kiruthika. "Structure activity Relationship Study of Simple Hydroxyl Coumarins as Antioxidant to Scavenge Hydrogen peroxide." RESEARCH REVIEW International Journal of Multidisciplinary 4, no. 6 (2019): 675–82. https://doi.org/10.5281/zenodo.3275482.

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Coumarins are heterocyclic compounds; structurally constructed by α-pyrone ring, fused with benzene ring. Coumarins are very interested because of their abundance in nature and their tremendous pharmacological properties such as anticoagulant, anticancer, antibacterial, anti-inflammatory, anti-tuberculosis, antioxidant, etc.The need for the antioxidant is very important because of the role reactive oxygen species and its contribution to many deleterious effects in human body. Hydrogen peroxide is such a reactive oxygen species. This study focused on synthesizing the parent compound,Couma
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Prahadeesh, N., Maheswaran Sithambaresan, and Umaramani Mathiventhan. "A Study on Hydrogen Peroxide Scavenging Activity and Ferric Reducing Ability of Simple Coumarins." Emerging Science Journal 2, no. 6 (2018): 417. http://dx.doi.org/10.28991/esj-2018-01161.

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Coumarin compounds are δ-lactones where α-pyrone ring is fused with benzene ring. Coumarins are widely distributed in the plant kingdom as well as they are very important in synthetic organic chemistry. Coumarins have great interest because of their abundance in nature and diverse pharmacological activities including antibacterial, antiviral, antipyretic, and anticoagulant, antioxidant, anti-inflammatory and anticancer. This study focused on synthesizing different simple Coumarins and studying their antioxidant activity. Four simple Coumarins (Coumarin (C1), 4-hydroxy coumarin (C2), 7-hydroxy
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Nagaretnam, Prahadeesh, and Sithambaresan Maheswaran. "Synthesis of Simple Coumarins: Mixed Solvent Recrystallization Approach and Modification." RESEARCH REVIEW International Journal of Multidisciplinary 4, no. 1 (2019): 455–61. https://doi.org/10.5281/zenodo.2548800.

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Coumarin compounds have great interest for their wide range of medicinal and pharmacological properties as well as for their fluorescent properties. Simple coumarins are being the major precursor for the synthesis of most of the coumarin derivatives. Simple coumarin (C1) was synthesized by using Perkin condensation reaction whereas 7-hydroxy coumarin (C2) and 7-hydroxy-4-methyl coumarin (C3) were synthesized by using Pechmann condensation reaction. Solvent combination which gives higher recovery percentage on recrystallization was found out. The synthesized simple coumarins were characterized
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Zhou, Dejun, Youchao Zhuang, and Zuntian Sheng. "Study on effective synthesis of 7-hydroxy-4-substituted coumarins." Heterocyclic Communications 28, no. 1 (2022): 181–87. http://dx.doi.org/10.1515/hc-2022-0154.

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Abstract Many coumarin derivatives have good biological activity and application value in fluorescent probes. Therefore, synthetic routes to coumarin derivatives have also attracted the attention of many research groups. In this work, based on the Pechmann coumarin synthesis method, the influence of various Lewis acids on the reaction was discussed, and the optimal synthesis conditions of 7-hydroxy-4-substituted coumarins were explored. Based on the experimental results, a possible mechanism was proposed, which provides a reference for future industrialized production of coumarins.
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Rahayu, D. U. C., R. S. Al-Laily, D. A. Khalwani, et al. "MICROWAVE-ASSISTED SYNTHESIS OF 4-METHYL COUMARINS, THEIR ANTIOXIDANT AND ANTIBACTERIAL ACTIVITIES." RASAYAN Journal of Chemistry 15, no. 02 (2022): 1053–62. http://dx.doi.org/10.31788/rjc.2022.1526780.

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Coumarins are heterocyclic compounds naturally found in plants. Coumarin-derived compounds have been commonly synthesized and some have exhibited a wide range of bioactivities. In searching for coumarins-based antioxidants and antibacterial, in this study, various 4-methyl coumarins have been synthesized by reacting ethyl acetoacetate with several phenol compounds, e.g. resorcinol, catechol, hydroquinone, α-naphthol, and β-naphthol, catalyzed by multiple Lewis acids, e.g. SnCl2, SnCl2.2H2O, ZnCl2, and AlCl3, using microwave irradiation via the Pechmann condensation. The antioxidant activities
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Prabawati, Susy Yunita, and Fitriana Fitriana. "Synthesis of 7-(Hydroxy) Coumarin and Its Activity Test As Antibacterial against Staphylococcus aureus and Shigella flexneri." Proceeding International Conference on Science and Engineering 1 (October 31, 2017): 141–45. http://dx.doi.org/10.14421/icse.v1.285.

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A synthesis of 7-(hydroxy)coumarin and its activity as antibacterial against Staphylococcus aureus and Shigella flexneri has been performed. The synthesis of the coumarin was carried out by reacting ethyl acetate and 2,4-dihydroxybenzaldehyde using piperidine as an alkaline catalyst via Knoevenagel reaction and antibacterial activity test was performed using disc diffusion method. The product of 7- (hydroxy)coumarin was obtained as a bright brown crystalline (m.p. 125 °C) with a rendment of 77%. The FTIR spectrum shows the absorption of -OH groups at 3101,54 cm-1 and unsaturated lactone groups
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Ukirde, R. D., R. B. Patil, and S. D. Sawant. "Design, Synthesis and Evaluation of Antioxidant Activity of Some Coumarin Derivatives." Asian Journal of Organic & Medicinal Chemistry 4, no. 3 (2019): 138–43. http://dx.doi.org/10.14233/ajomc.2019.ajomc-p172.

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Coumarin derivatives are an important class of heterocyclic compounds, specifically 4-amino substituted coumarins with antioxidant, anticancer activities. The above observations prompted us to synthesize new coumarins with various substitutions. The starting material 4-chloro-2H-chromen-2-one was synthesized by refluxing a mixture of 4-hydroxy-2H-chromen-2-one in phosphoryl chloride. The 4-substituted amine derivatives of coumarin were synthesized by refluxing 4-chloro-2H-chromen-2- one with 4-substituted amines and anhydrous K2CO3 and methanol. All the eleven 4-substituted amine derivatives o
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Zaichenko, Natalia L., Tatyana M. Valova, Olga V. Venidiktova, et al. "Excited State Proton Transfers in Hybrid Compound Based on Indoline Spiropyran of the Coumarin Type and Azomethinocoumarin in the Presence of Metal Ions." Molecules 26, no. 22 (2021): 6894. http://dx.doi.org/10.3390/molecules26226894.

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Spectral-luminescence properties of a hybrid compound containing a coumarin-type spiropyran and an azomethinocoumarin fragment in toluene-acetonitrile solution in the presence of Li+, Ca2+, Zn2+ and Mg2+ ions are reported. Two excited state proton transfers can occur in the hybrid compound—the transfer of a proton from the OH group of the 7-hydroxy coumarin tautomer to the N atom of the C=N bond of the azomethine fragment leading to green ESIPT fluorescence with a maximum at 540 nm and from the OH group of the 7-hydroxy coumarin tautomer to the carbonyl group of the pyrone chromophore, which l
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Pandya, Mahesh K., Tapan H. Parekh, Mehulsinh R. Chhasatia, and Nileshkumar D. Vala. "Synthesis and characterization of some novel coumarin based various 2-aryl-pyrido [3,2-c] coumarins." Journal of Drug Delivery and Therapeutics 10, no. 2 (2020): 158–63. http://dx.doi.org/10.22270/jddt.v10i2.3933.

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A survey of the literature reveals that the number of coumarin derivatives having heterocyclic moieties either as substituent groups or fused with parent coumarin nucleus possesses a variety of functions and are widely used in drugs and dyes. Because of this wide utility, the synthesis of coumarin has remained a subject of active interest. Looking at the importance of these heterocoumarins and with a view to exploring new methods of their synthesis, the present work was undertaken and this synthesis deals with various 2-aryl-pyrido [3,2-c] coumarins. The compounds have been synthesized by reac
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Baviskar, Pavan Devidas, Arun Dinkar Kale, Vilas Nana Mahire, Swati Dnyaneshwarpuri Gosavi, Dipak Sharadrao Dalal, and Pramod Pandurang Mahulikar. "Aqueous hydrotropes: An efficient and reusable catalyst for the synthesis of 3-carboxy-coumarin motifs at room temperature." European Journal of Chemistry 15, no. 3 (2024): 239–44. http://dx.doi.org/10.5155/eurjchem.15.3.239-244.2538.

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The coumarin moiety plays an important role in the large number of natural products possessing different kinds of biological diversity. Coumarin carboxylic acids show a wide range of biological activities in the pharmaceutical and agricultural fields. Knoevenagel condensation is one of the important reaction pathways for synthesizing coumarin derivatives, and many methodologies have been developed to synthesize this class of compounds. A more environmentally friendly method of synthesizing 3-carboxy coumarins has been successfully carried out using 50% aqueous NaPTS hydrotropes at room tempera
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Dissertations / Theses on the topic "Hydroxy coumarin"

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Louit, Guillaume. "Développement de sondes fluorescentes du radical hydroxyle : caractérisation et modélisation de la réactivité de molécules dérivées de la coumarine avec HO." Paris 11, 2005. http://www.theses.fr/2005PA112170.

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Le radical hydroxyle, molécule ubiquitaire, intervient dans de nombreux domaines allant des phénomènes de stress oxydant aux mécanismes majeurs de la chimie atmosphérique. Outre l'intérêt d'étudier la cause de dommages oxydatifs en milieu biologique, la détection de HO• permet également d'effectuer des dosimétries lorsqu'il est produit par des rayonnements ionisants. L'objectif de cette thèse a été double :- Améliorer les méthodes de détection de HO• par la mise au point de nouvelles sondes,- Contribuer à la compréhension des mécanismes réactionnels dans lesquels il intervient. Nous avons util
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Khunoana, Sewela. "Identification, characterization and quantification of the active and toxic compounds of two cinnamon species." Thesis, 2012. http://hdl.handle.net/10210/5042.

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M.Tech.<br>There are over 250 cinnamon species existing worldwide, and amongst them, 2 species Cinnamomum cassia and Cinnamomum zeylanicum, are commonly used all over the world as spices, fragrances in perfumes and as medicines. These two species are distinguished from each other by the presence and absence of certain compounds depending on the origin and distribution of the plant. Nevertheless, all cinnamon species contain essential oils and water soluble components and the composition of these components found in each species depends on the type of species involved. These components are made
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Kuo, Pei-Yu, and 郭佩玉. "Part I. Unique property of cyclopropanecarbonyl group and its potential applications Part II. Reactions of 7-N,N-dimethylamino-4-hydroxy coumarin triketone derivatives and their potential applications." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/06698498192905205842.

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博士<br>東海大學<br>化學系<br>98<br>Abstract Part I、Unique property of cyclopropanecarbonyl group and its potential applications Various cyclopropylcarbonyl containing compounds have been designed and synthesized, and their X-ray crystal structures and proton NMR spectra have been determined. The collected information suggested that when the oxygen atom of a cyclopropanecarbonyl group is hydrogen bonded or metal chelated, the cyclopropyl group will adopt the bisected conformation. Furthermore, the carbonyl carbon is less susceptible to a nucleophilic attack than corresponding alkylcarbonyl groups. T
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Lin, Jiun-Han, and 林君翰. "Part I : One-pot Tandem Synthesis of a Coumarin / Naphthoquinone Monoimine-based Oxazabicycle and Its Fluorescence Redox-switching PropertiesPart II : Synthesis of 4-Hydroxy-7-dimethylamino-3-pyrazolinylcoumarin Derivatives and Their Solvatochromic an." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/01516014209402314283.

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碩士<br>東海大學<br>化學系<br>98<br>Part I : One-pot Tandem Synthesis of a Coumarin / Naphthoquinone Monoimine-based Oxazabicycle and Its Fluorescence Redox-switching Properties A coumarin/naphthoquinone monoimine-fused oxazabicyclic derivative was designed, synthesized, and characterized in a one-pot tandem reaction and its fluorescence redox switch properties were investigated. The coumarin emission of the synthesized oxazabicycle is completely quenched by the naphthoquinone monoimine moiety, the corresponding reduced aminonaphthalenol resulted in a moderate increase of the emission intensity. T
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Gao, Bing-Fong, and 高秉豐. "Organocascade Synthesis of Annulated (Z)-2-Methylene Pyrans: Nucleophilic Conjugate Addition of Hydroxy Coumarins toBranched Nitroenynes via Allene Formation/Oxa-Michael Cyclization/Alkene Isomerization Sequence." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/5w38m9.

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碩士<br>國立臺灣師範大學<br>化學系<br>104<br>Enantioselective organocatalysis has contributed significantly to asymmetric synthesis by delivering highly functionalized complex structural entities with multiple stereogenic centers in high optical purity. Most of enyne system in previous literature was studied to establish by using synergistic/sequential metal catalysis, but it was the few on organic asymmetric cascade reaction. The organocascade reaction was established between 1,3-nitro enynes and 4-hydroxy coumarin to afford pyrano-annulated scaffolds in high yields (up to 88% yield) and excellent stereos
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Lee, Chia-Jui, та 李家睿. "Direct β-Acylation of 2-Arylidene-1,3-indandiones withAcyl Chlorides Catalyzed by OrganophosphanesPreparation of Furo[3,2-c]coumarins from 3-cinnamoyl-4-hydroxy-2H-chromen-2-ones and Acyl Chlorides: A Bu3P-Mediated C-Acylation/Cyclization SequenceSynthesis of Functionalized Furans via Chemoselective Reduction/Wittig reaction Using Catalytic Triethylamine and Phosphine". Thesis, 2016. http://ndltd.ncl.edu.tw/handle/58559388773676205184.

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博士<br>國立臺灣師範大學<br>化學系<br>104<br>In part I, we have developed an organophosphane-catalyzed direct β-acylation of a series of conjugated systems bearing ketone, amide and ester functionalities using acyl chlorides as trapping reagents. A wide variety of highly functional ketone derivatives were generated efficiently under very mild conditions with high yields according to our protocol. Our adducts can even be utilized as important building blocks for the synthesis of functional tri/tetracyclic pyridazine derivatives. In part II, electrophilic addition of acyl chlorides to 3- cinnamoyl-4-hydroxy
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Cherdchim, Banyat. "Actions of lignocellulolytic enzymes on Abies grandis(grand fir) wood for application in biofuel production." Doctoral thesis, 2010. http://hdl.handle.net/11858/00-1735-0000-0006-B138-4.

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Book chapters on the topic "Hydroxy coumarin"

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Jaseela, M. A., T. M. Suhara, and K. Muraleedharan. "A DFT investigation of the influence of α,β unsaturation in chemical reactivity of coumarin and some hydroxy coumarins." In Computational Chemistry Methodology in Structural Biology and Materials Sciences. Apple Academic Press, 2017. http://dx.doi.org/10.1201/9781315207544-2.

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Favretto*, D., P. Traldi*, M. Hamdamt, O. Curcuruto†, G. Innocenti+, and R. Caniato+. "A comparison of FAB MS, HPLC-MS, and CZE-ES MS in the characterization of the alcoholic extracts of Haplophyllum patavinum." In Applications of Modern Mass Spectrometry in Plant Science Research. Oxford University PressOxford, 1996. http://dx.doi.org/10.1093/oso/9780198549659.003.0014.

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Abstract Several species of Haplophyllum are known to contain coumarin-related compounds including umbelliferone, scopoletin, xanthyletin, seselin, and 5- hydroxy-7-methoxycoumarin. Due to the biological relevance of these substances, both the chemotaxonomic rationalization of the content of coumarins and the search for new active compounds in these botanic species present a stimulating aim. In this context, our interest has recently been focused on Haplophyllum patavinum, whose spontaneous growth is more and more rare. For such reason, in vitro cultures have been undertaken; interestingly, th
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Supuran, Claudiu T. "Coumarins as Carbonic Anhydrase Inhibitors." In Flavonoids and Phenolics. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815079098122010013.

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Carbonic anhydrases (CAs, EC 4.2.1.1) are metalloenzymes and relevant drug targets with many medicinal chemistry applications. Their classes of inhibitors are in clinical use as diuretics, or drugs for the management of glaucoma, epilepsy, obesity, tumors and infectious diseases. Among the inhibitors discovered so far, coumarins constitute an interesting class. They undergo CA-catalyzed hydrolysis and act as “prodrug inhibitors”, forming 2-hydroxy-cinnamic acids, which bind at the entrance of the enzyme active site, which has a relevant variability of amino acid residues among the different CA
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"Shikimic Acid Pathway: Phenols." In Chemical Diversity of Plant Specialized Metabolites. Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671472-00163.

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Plant metabolites having one or more hydroxyl groups attached to an aromatic ring are known as phenols. Phenols are a heterogeneous group of compounds. One of the most important functions of phenols is in plant communication e.g., allelopathy, attracting pollinating and disseminating agents, attracting symbiotic bacteria, and inhibiting pathogens and predators. Some phenolic compounds (e.g., lignin) are structural components of plant cell wall. Phenols also protect the plant from oxidants and ultraviolet radiation. Due to the free radical scavenging properties, phenolics present in the human d
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V. Vastrad, Jyoti, Pratikhya Badanayak, and Giridhar Goudar. "Phenolic Compounds in Tea: Phytochemical, Biological, and Therapeutic Applications." In Phenolic Compounds - Chemistry, Synthesis, Diversity, Non-Conventional Industrial, Pharmaceutical and Therapeutic Applications. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.98715.

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Phenolic compounds are one of the major and most complex groups of phytochemicals found among plant kingdom. Structurally they comprise of aromatic ring along with one or more hydroxyl groups. Based on the structure they are divided into subgroups such as phenolic acids, flavonoids, tannins, coumarins, lignans, quinones, stilbenes and carotenoids. Plant polyphenols are gaining popularity as a result of their potent antioxidant properties and notable effects in the prevention of oxidative stress-related diseases. Extraction, identification and characterisation of phenolic compounds from various
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R.A. Mans, Dennis. "Naturally Occurring Antioxidants in Seven Well-Known Fruits from the Republic of Suriname (South America): Part 2." In Recent Developments in Antioxidants From Natural Sources [Working Title]. IntechOpen, 2023. http://dx.doi.org/10.5772/intechopen.110079.

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The dependence of humans on oxygen for their metabolism, together with their uninterrupted exposure to a wide variety of hazardous environmental chemicals, leads to the continuous formation of reactive oxygen-derived species (ROS) in the body such as superoxide radical anion, hydrogen peroxide, peroxyl radicals, and hydroxyl radical. When in excess, ROS can damage cellular constituents such as DNA and membrane lipids causing oxidative stress, cellular injury, and eventually, inflammatory, neoplastic, diabetic, cardiovascular, neurodegenerative, and age-related diseases. Fortunately, the body h
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R.A. Mans, Dennis. "Naturally Occurring Antioxidants in Seven Well-Known Fruits from the Republic of Suriname (South America): Part 1." In Recent Developments in Antioxidants From Natural Sources [Working Title]. IntechOpen, 2023. http://dx.doi.org/10.5772/intechopen.110078.

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The dependence of humans on oxygen for their metabolism, together with their uninterrupted exposure to a wide variety of hazardous environmental chemicals, leads to the continuous formation of reactive oxygen-derived species (ROS) in the body, such as superoxide radical anion, hydrogen peroxide, peroxyl radicals, and hydroxyl radical. When in excess, ROS can damage cellular constituents such as DNA and membrane lipids causing oxidative stress, cellular injury, and, eventually, inflammatory, neoplastic, diabetic, cardiovascular, neurodegenerative, and age-related diseases. Fortunately, the body
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R. Surana, Khemchand, Ritesh B. Pawar, Ritesh A. Khairnar, and Sunil K. Mahajan. "Protein Prenylation and Their Applications." In Modifications of Biomolecules [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.104700.

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Prenylation is a universal covalent post-translational modification found in all eukaryotic cells, comprising attachment of either a farnesyl or a geranylgeranyl isoprenoid. Prenyl group is important for protein-protein binding through specialized prenyl-binding domains. Farnesylation and geranyl geranylation are very important in C-terminal anchoring of proteins to the cell membrane. These post-translational modification are most often catalyzed by either protein farnesyl transferase (FTase) or protein geranyl geranyl transferase-I (GGTase-I). These enzymes typically recognize a CaaX motif, w
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Conference papers on the topic "Hydroxy coumarin"

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Antonijević, Marko, Žiko Milanović, Dušica Simijonović, Zoran Marković, and Snežana Marković S. Zoran. "ANTIOXIDATIVE POTENCY AND RADICAL SCAVENGING ACTIVITY OF SELECTED COUMARIN-HYBRIDS." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac,, 2021. http://dx.doi.org/10.46793/iccbi21.458a.

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In previous studies, it was found that coumarins with hydrazide moiety show good antioxidative potential, while similar coumarins with hydrazone moiety are good anticancer agents. In this paper, the antioxidative potency and radical scavenging activity of two coumarin hydrazone derivatives were investigated. For this purpose, density functional theory method M062X with 6-311G++(d,p) basis set was implemented. It was found that investigated compounds exhibit good antioxidative potency, with very similar BDE values regardless of the position involved. On the other hand, PA values show that a pre
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Simijonović, Dušica, Marko Antonijević, Edina Avdović, Zorica Petrović, and Zoran Marković. "INHIBITORY EFFECT OF COUMARIN BENZOYLHYDRAZONES ON MCL-1 PROTEIN." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2021. http://dx.doi.org/10.46793/iccbi21.442s.

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The protein that controls cell differentiation in acute myeloid leukemia is MCL-1. High-level of this protein causes the carcinogenesis. In this paper inhibitory effect of two coumarin benzoylhydrazones,(E)-2-hydroxy-N’-(1-(2-oxo-2H-chromen-3-yl)ethylidene)benzohydrazide (A) and (E)-4-hydroxy-N’-(1-(2-oxo-2H-chromen-3-yl)ethylidene)benzohydrazide (B) against MCL-1 protein was investigated. For this purpose, a molecular docking simulations were used. The obtained results showed that compound A showed better activity than compound B. Also, the docking simulations against MCL-1 protein were perfo
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Avdović, Edina, Sandra Jovičić Milić, Dušica Simijonović, Danijela Stojković, Dejan Milenković, and Zoran Marković. "SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION AND BSA INTERACTIONS OF 3-(1-((4-HYDROXY PENTYLAMINO)ETHYLIDENE)CHROMAN-2,4-DIONE." In 17th International Conference on Fundamental and Applied Aspects of Physical Chemistry. Society of Physical Chemists of Serbia, 2024. https://doi.org/10.46793/phys.chem24i.053a.

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In this study, we synthesized a novel coumarin derivative, specifically 3-(1-((4-hydroxy pentylamino)ethylidene)cromane-2,4-dione by the reaction of 3-acetyl-4-hydroxycoumarin and 5- aminopentanol in methanol. The compound was obtained after 2 hours of reflux. The synthesized coumarin derivative was obtained in very good yield (80%) and characterized using elemental microanalysis, Uv-Vis, IR and NMR spectroscopy. Furthermore, the interaction of investigated compound with bovine serum albumin (BSA) was studied using fluorescence spectroscopy and the Stern-Volmer constant (Ksv), quenching rate c
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Rabe, T., P. Görrn, T. Riedl, and W. Kowalsky. "Optical gain in Coumarin 545T-doped Tris(8-hydroxy-chinolinato)aluminium thin films." In Photonic Devices + Applications, edited by Zakya H. Kafafi and Franky So. SPIE, 2007. http://dx.doi.org/10.1117/12.733875.

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Pramod, A. G., and C. G. Renuka. "Theoretical analysis of 3,3’-(naphthalen-2-ylmethylene) bis (4-hydroxy-2H-chromen-2-one) coumarin derivative." In 3RD INTERNATIONAL CONFERENCE ON CONDENSED MATTER AND APPLIED PHYSICS (ICC-2019). AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0001780.

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Radojević, Ivana, Edina Avdović, Dušan Dimić, Marko Antonijević, Marijana Vasić та Katarina Ćirković. "ANTIMICROBIAL ACTIVITY OF HYBRIDS OF COUMARIN’S DERIVATIVES WITH NEUROTRANSMITTERS 20242ND INTERNATIONAL SYMPOSIUM ON BIOTECHNOLOGY (2024)ЗБОРНИЦИ". У 2nd International Symposium on Biotechnology. Faculty of Agronomy in Čačak, University of Kragujevac, 2024. http://dx.doi.org/10.46793/sbt29.70ir.

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n this study, the antimicrobial activity of five hybrids of 3-acetyl- 4-hydroxy coumarin with neurotransmitters was determined: dopamine (1), tyramine (2), octopamine (3), norepinephrine (4) and methoxy-tyramine (5). Antimicrobial activity was assessed using the microdilution method incorporating resazurin, with determination of MIC/MMC concentrations. Testing involved twelve microorganisms, five of which were sourced from mine wastewater. The best activities were shown by substances (1) and (4) on Bacillus pumilus and Pantoea agglomerans, where the MIC was 31.8 μg/mL. Pantoea agglomerans show
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Antonijevic, Marko, Dejan Milenkovic, Ana Kesic, Edina Avdovic, and Zoran Markovic. "ANTIRADIKALSKI KAPACITET (E)-N’-1-(2,4-DIOKSO-2H-HROMEN-3(4H)-ILIDENE)ETIL)-4-HIDROKSI-3-METOKSIBENZOHIDRAZIDA." In XXVI savetovanje o biotehnologiji sa međunarodnim učešćem. University of Kragujevac, Faculty of Agronomy, 2021. http://dx.doi.org/10.46793/sbt26.423a.

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Coumarins are a widespread group of compounds. They have a wide range of physiological effects, from antifungal, through anticoagulant to anticancer, and therefore they have found wide application in the treatment of various diseases. In this paper, the ability of 4-hydroxy-3-methoxy-N'-((E)-1-(2,4-dioxo-2H-chromen-3(4H)-ylidene)ethyl)benzohydrazide to inactivate ROS was investigated. The analysis of the obtained results showed that the SET-PT (Single Electron Transfer Followed By Proton Transfer) mechanism is non-operative. On the other hand, the thermodynamic parameters describing the HAT *H
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Barancelli, Daniela Aline, Airton G. Salles Jr., Jason G. Taylor, and Carlos Roque D. Correia. "Coumarins from Free ortho-Hydroxy Cinnamates by Heck- Matsuda Arylations and their Application in the Total Synthesis of (R)-Tolterodine." In 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_2013816201342.

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9

Ohindovschi, Angelica, and Maria Cojocaru-Toma. "Identification of phenolic compounds from extract of Galium verum." In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab21.

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The species Galium verum has a long history as a traditional healing herb and attracted attention for intense investigation in recent years as it proves to be a safe, affordable and effective natural health remedy as a choleretic, diuretic or spasmolytic [1]. There is detailed research showing a complex and rich content of phytochemicals in the flowers and leaves of G. verum, with the highest total composition of phenols and flavonoids [2]. For the determination of phenolic compounds, the plant extract was obtained from Galii veri herba, collected during the flowering period and treated with 6
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