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Journal articles on the topic 'Hydroxycinnamates'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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1

Bahri, Meriem, Philippe Hance, Sébastien Grec, et al. "A “Novel” Protocol for the Analysis of Hydroxycinnamic Acids in Leaf Tissue of Chicory (Cichorium intybusL., Asteraceae)." Scientific World Journal 2012 (2012): 1–8. http://dx.doi.org/10.1100/2012/142983.

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A “novel” protocol is presented for easy and reliable estimation of soluble hydroxycinnamate levels inCichorium intybusL. leaf tissue in large-scale experiments. Samples were standardized by punching 6 discs per leaf, and hydroxycinnamates were extracted by submerging the discs in 80% ethanol with 5% acetic acid for at least 48 h in the darkness at 4°C. Residual dry mass of the discs was used fora posterioricorrection of compound levels. Chlorophyll was eliminated by chloroform, and the aqueous phases were transferred to microplates, dried, and dissolved in 50% methanol for HPLC analysis and s

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2

López-Malvar, Ana, Zoila Reséndiz, Rogelio Santiago, José Cruz Jiménez-Galindo, and Rosa Ana Malvar. "Relationships between Stalk Resistance and Corn Borers, Agronomic Traits, and Cell Wall Hydroxycinnamates in a Set of Recombinant Inbred Lines from a Maize MAGIC Population." Agronomy 11, no. 6 (2021): 1132. http://dx.doi.org/10.3390/agronomy11061132.

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Corn borers are the most important pest affecting maize. Resistance to corn borer attack may compromise plant fitness being detrimental for some important agronomic traits such as yield. Against the attack of this pest, cell wall-bound hydroxycinnamates have been previously described as a possible defense mechanism. In this study, agronomic characterization and cell wall-bound hydroxycinnamates quantification was performed in a subset of Recombinant Inbred Lines (RILs) from a Multiparent Advanced Generation Intercross (MAGIC) population that showed contrasting behavior against corn borer attac

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3

Ralph, John. "Hydroxycinnamates in lignification." Phytochemistry Reviews 9, no. 1 (2009): 65–83. http://dx.doi.org/10.1007/s11101-009-9141-9.

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4

Graça, José. "Hydroxycinnamates in suberin formation." Phytochemistry Reviews 9, no. 1 (2009): 85–91. http://dx.doi.org/10.1007/s11101-009-9138-4.

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5

Boeck, Florian, Max Blazejak, Markus R. Anneser, and Lukas Hintermann. "Cyclization of ortho-hydroxycinnamates to coumarins under mild conditions: A nucleophilic organocatalysis approach." Beilstein Journal of Organic Chemistry 8 (September 26, 2012): 1630–36. http://dx.doi.org/10.3762/bjoc.8.186.

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(E)-Alkyl ortho-hydroxycinnamates cyclize to coumarins at elevated temperatures of 140–250 °C. We find that the use of tri-n-butylphosphane (20 mol %) as a nucleophilic organocatalyst in MeOH solution allows cyclization to take place under much milder conditions (60–70 °C). Several coumarins were prepared, starting from ortho-hydroxyarylaldehydes, by Wittig reaction with Ph3P=CHCO2Me to (E)-methyl ortho-hydroxycinnamates, followed by the phosphane catalyzed cyclization.

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6

Joachimiak, Andrzej, Grazyna Joachimiak, Lance Bigelow, Garrett Cobb, and Youngchang Kim. "HcaR Ligand and DNA Interactions in the Regulation of Catabolic Gene Expression." Acta Crystallographica Section A Foundations and Advances 70, a1 (2014): C203. http://dx.doi.org/10.1107/s2053273314097964.

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Precise tuning of gene expression by transcriptional regulators determines the response to internal and external chemical signals and adjusts the metabolic machinery for many cellular processes. As a part of ongoing efforts by the Midwest Center for Structural Genomics, a number of transcription factors were selected to study protein-ligand and protein-DNA interactions. HcaR, a new member of the MarR/SlyA family of transcription regulators from soil bacteria Acinetobacter sp. ADP1, is an evolutionarily atypical regulator and represses hydroxycinnamate (hca) catabolic genes. Hydroxycinnamates c

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7

Lin, Long-Ze, and James M. Harnly. "LC-PDA-ESI/MS Identification of the Phenolic Components of Three Compositae Spices: Chamomile, Tarragon, and Mexican Arnica." Natural Product Communications 7, no. 6 (2012): 1934578X1200700. http://dx.doi.org/10.1177/1934578x1200700615.

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Chamomile ( Matricaria chamomilla L.), tarragon ( Artemisia dracunculus L.) and Mexican arnica ( Heterotheca inuoides) are common compositae spices and herbs found in the US market. They contain flavonoids and hydroxycinnamates that are potentially beneficial to human health. A standardized LC-PDA-ESI/MS profiling method was used to identify 51 flavonoids and 17 hydroxycinnamates. Many of the identifications were confirmed with authentic standards or through references in the literature or the laboratory's database. More than half of the phenol compounds for each spice had not been previously

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8

Smith, Michael A., Valerie B. Weaver, David M. Young, and L. Nicholas Ornston. "Genes for Chlorogenate and Hydroxycinnamate Catabolism (hca) Are Linked to Functionally Related Genes in the dca-pca-qui-pob-hca Chromosomal Cluster of Acinetobacter sp. Strain ADP1." Applied and Environmental Microbiology 69, no. 1 (2003): 524–32. http://dx.doi.org/10.1128/aem.69.1.524-532.2003.

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ABSTRACT Hydroxycinnamates are ubiquitous in the environment because of their contributions to the structure and defense mechanisms of plants. Additional plant products, many of which are formed in response to stress, support the growth of Acinetobacter sp. strain ADP1 through pathways encoded by genes in the dca-pca-qui-pob chromosomal cluster. In an appropriate genetic background, it was possible to select for an Acinetobacter strain that had lost the ability to grow with caffeate, a commonly occurring hydroxycinnamate. The newly identified mutation was shown to be a deletion in a gene desig

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9

Kisiel, Wanda, and Jasmin Jakupowic. "Long-Chain Alkyl Hydroxycinnamates fromCrepis taraxacifolia." Planta Medica 61, no. 01 (1995): 87–88. http://dx.doi.org/10.1055/s-2006-958012.

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10

VRHOVŠEK, Urška. "Resveratrol and hydroxycinnamic acids substances in wine for the prevention of coronary artery disease." Acta agriculturae Slovenica 73, no. 1 (1999): 39–47. http://dx.doi.org/10.14720/aas.1999.73.1.15961.

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It is widely confirmed that red wines contain significantly high amounts of polyphenolic antioxidants. Therefore, a moderate, regular and appropriate wine consumption, possibly associated with meals, surely represents a primary source for these compounds. It is necessary to be cautious in making general recommendations, since advice to drink some alcoholic beverages to avoid coronary heart disease and some kinds of cancer could possibly encourage abuse. In this paper two groups of nonflavonoids, resveratrol and hydroxycinnamates, are described in greater detail. It is worth stressing that, as

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11

Seguido, Miguel Ángel, Rosa María Tarradas, Susana González-Rámila, et al. "Influence of 8-week daily consumption of a new product combining green coffee hydroxycinnamates and beta-glucans on polyphenol bioavailability in subjects with overweight and obesity." Food & Function 13, no. 3 (2022): 1133–52. http://dx.doi.org/10.1039/d1fo03327a.

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12

Mnich, Ewelina, Nanna Bjarnholt, Aymerick Eudes, et al. "Phenolic cross-links: building and de-constructing the plant cell wall." Natural Product Reports 37, no. 7 (2020): 919–61. http://dx.doi.org/10.1039/c9np00028c.

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13

Nunes, Fernando M., and Manuel A. Coimbra. "Role of hydroxycinnamates in coffee melanoidin formation." Phytochemistry Reviews 9, no. 1 (2009): 171–85. http://dx.doi.org/10.1007/s11101-009-9151-7.

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14

Parke, Donna, and L. Nicholas Ornston. "Hydroxycinnamate (hca) Catabolic Genes from Acinetobacter sp. Strain ADP1 Are Repressed by HcaR and Are Induced by Hydroxycinnamoyl-Coenzyme A Thioesters." Applied and Environmental Microbiology 69, no. 9 (2003): 5398–409. http://dx.doi.org/10.1128/aem.69.9.5398-5409.2003.

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ABSTRACT Hydroxycinnamates are plant products catabolized through the diphenol protocatechuate in the naturally transformable bacterium Acinetobacter sp. strain ADP1. Genes for protocatechuate catabolism are central to the dca-pca-qui-pob-hca chromosomal island, for which gene designations corresponding to catabolic function are dca (dicarboxylic acid), pca (protocatechuate), qui (quinate), pob (p-hydroxybenzoate), and hca (hydroxycinnamate). Acinetobacter hcaC had been cloned and shown to encode a hydroxycinnamate:coenzyme A (CoA) SH ligase that acts upon caffeate, p-coumarate, and ferulate,

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15

Trachtenberg, Aviram, Katarzyna Sidoryk, Somaya Alreate, et al. "Structure-Activity Relationship of Hydroxycinnamic Acid Derivatives for Cooperating with Carnosic Acid and Calcitriol in Acute Myeloid Leukemia Cells." Biomedicines 9, no. 11 (2021): 1517. http://dx.doi.org/10.3390/biomedicines9111517.

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Plant phenolic compounds have shown the ability to cooperate with one another at low doses in producing enhanced anticancer effects. This may overcome the limitations (e.g., poor bioavailability and high-dose toxicity) in developing these agents as cancer medicines. We have previously reported that the hydroxycinnamic acid derivative (HCAD) methyl-4-hydroxycinnamate and the phenolic diterpene carnosic acid (CA) can synergistically induce massive calcium-dependent apoptosis in acute myeloid leukemia (AML) at non-cytotoxic concentrations of each agent. Here, we explored the chemical nature of th

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16

Gómez-Juaristi, Miren, Sara Martínez-López, Beatriz Sarria, Laura Bravo, and Raquel Mateos. "Bioavailability of hydroxycinnamates in an instant green/roasted coffee blend in humans. Identification of novel colonic metabolites." Food & Function 9, no. 1 (2018): 331–43. http://dx.doi.org/10.1039/c7fo01553d.

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Reduced forms of hydroxycinnamates as new microbial metabolites after intake of a green/roasted coffee blend, together with the predominant phase II metabolites of reduced hydroxycinnamic acids, represented the most abundant group of colonic metabolites.

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17

Deacon, Glen B., Peter C. Junk, Winnie W. Lee, Maria Forsyth, and Jun Wang. "Rare earth 3-(4′-hydroxyphenyl)propionate complexes." New Journal of Chemistry 39, no. 10 (2015): 7688–95. http://dx.doi.org/10.1039/c5nj00787a.

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Structural variation of lanthanoid 3-(4′-hydroxyphenyl)propionates and investigation of the anti-corrosion properties of lanthanum 3-(4′-hydroxyphenyl)propionate are presented, highlighting lanthanoid contraction and the importance of the –CHCH− structural unit of 4-hydroxycinnamates in corrosion mitigation.

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18

Pannala, Ananthsekher, Raghib Razaq, Barry Halliwell, Surinder Singh, and Catherine A. Rice-Evans. "Inhibition of Peroxynitrite Dependent Tyrosine Nitration by Hydroxycinnamates." Free Radical Biology and Medicine 24, no. 4 (1998): 594–606. http://dx.doi.org/10.1016/s0891-5849(97)00321-3.

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19

Upton, Brianna M., and Andrea M. Kasko. "Biomass-Derived Poly(ether-amide)s Incorporating Hydroxycinnamates." Biomacromolecules 20, no. 2 (2019): 758–66. http://dx.doi.org/10.1021/acs.biomac.9b00044.

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20

Russell, Wendy R., Mark J. Burkitt, Gordon J. Provan, and Andrew Chesson. "Structure-specific functionality of plant cell wall hydroxycinnamates." Journal of the Science of Food and Agriculture 79, no. 3 (1999): 408–10. http://dx.doi.org/10.1002/(sici)1097-0010(19990301)79:3<408::aid-jsfa265>3.0.co;2-q.

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21

Parke, Donna, and L. Nicholas Ornston. "Toxicity Caused by Hydroxycinnamoyl-Coenzyme A Thioester Accumulation in Mutants of Acinetobacter sp. Strain ADP1." Applied and Environmental Microbiology 70, no. 5 (2004): 2974–83. http://dx.doi.org/10.1128/aem.70.5.2974-2983.2004.

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ABSTRACT Hydroxycinnamates, aromatic compounds that play diverse roles in plants, are dissimilated by enzymes encoded by the hca genes in the nutritionally versatile, naturally transformable bacterium Acinetobacter sp. strain ADP1. A key step in the hca-encoded pathway is activation of the natural substrates caffeate, p-coumarate, and ferulate by an acyl:coenzyme A (acyl:CoA) ligase encoded by hcaC. As described in this paper, Acinetobacter cells with a knockout of the next enzyme in the pathway, hydroxycinnamoyl-CoA hydratase/lyase (HcaA), are extremely sensitive to the presence of the three

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22

Menezes, Jose C. J. M. D. S., Shrivallabh P. Kamat, Jose A. S. Cavaleiro, Alexandra Gaspar, Jorge Garrido, and Fernanda Borges. "Synthesis and antioxidant activity of long chain alkyl hydroxycinnamates." European Journal of Medicinal Chemistry 46, no. 2 (2011): 773–77. http://dx.doi.org/10.1016/j.ejmech.2010.12.016.

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23

Park, Byoung-Jae, Chiho Yamahira, Cheol-Ho Park, Hiroaki Samejima, Kwang-Jin Chang, and Michio Onjo. "Hydroxycinnamates and Flavonoids from the Flower of Fagopyrum esculentum." Chemistry of Natural Compounds 54, no. 4 (2018): 766–68. http://dx.doi.org/10.1007/s10600-018-2468-y.

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24

Kroon, Paul A., and Gary Williamson. "Hydroxycinnamates in plants and food: current and future perspectives." Journal of the Science of Food and Agriculture 79, no. 3 (1999): 355–61. http://dx.doi.org/10.1002/(sici)1097-0010(19990301)79:3<355::aid-jsfa255>3.0.co;2-g.

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25

Faulds, Craig B., and Gary Williamson. "The role of hydroxycinnamates in the plant cell wall." Journal of the Science of Food and Agriculture 79, no. 3 (1999): 393–95. http://dx.doi.org/10.1002/(sici)1097-0010(19990301)79:3<393::aid-jsfa261>3.0.co;2-h.

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26

Schär, Aline, Silvia Liphardt, and Laura Nyström. "Enzymatic synthesis of steryl hydroxycinnamates and their antioxidant activity." European Journal of Lipid Science and Technology 119, no. 5 (2016): 1600267. http://dx.doi.org/10.1002/ejlt.201600267.

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27

Yarullina, Liubov, Ekaterina A. Cherepanova, Guzel F. Burkhanova, et al. "Stimulation of the Defense Mechanisms of Potatoes to a Late Blight Causative Agent When Treated with Bacillus subtilis Bacteria and Chitosan Composites with Hydroxycinnamic Acids." Microorganisms 11, no. 8 (2023): 1993. http://dx.doi.org/10.3390/microorganisms11081993.

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Phytophthora infestans is, worldwide, one of the main causal agents of epiphytotics in potato plantings. Prevention strategies demand integrated pest management, including modeling of beneficial microbiomes of agroecosystems combining microorganisms and natural products. Chitooligosaccharides and their derivatives have great potential to be used by agrotechnology due to their ability to elicit plant immune reactions. The effect of combining Bacillus subtilis 26D and 11VM and conjugates of chitin with hydroxycinnamates on late blight pathogenesis was evaluated. Mechanisms for increasing the res

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28

Kondrashev, Sergey, Nadezhda Nesterova, Alexey Luzin, Vitaliy Kochanov, Anna Luzina, and Alexey Matyushin. "Qualitative and Quantitative Assay of Hydroxycinnamates of Prunus spinosa L." Pharmacognosy Journal 12, no. 1 (2020): 157–61. http://dx.doi.org/10.5530/pj.2020.12.23.

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29

Kern, Sandra M., Richard N. Bennett, Fred A. Mellon, Paul Anthony Kroon, and Maria-Teresa Garcia-Conesa. "Absorption of Hydroxycinnamates in Humans after High-Bran Cereal Consumption." Journal of Agricultural and Food Chemistry 51, no. 20 (2003): 6050–55. http://dx.doi.org/10.1021/jf0302299.

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30

Chatterjee, Prabal K., Benjamin Elisha-Lambert, and Ananth S. Pannala. "Dietary Hydroxycinnamates and Resveratrol Reduce Oxidant Injury in Renal Cells." Proceedings for Annual Meeting of The Japanese Pharmacological Society WCP2018 (2018): PO1–3–4. http://dx.doi.org/10.1254/jpssuppl.wcp2018.0_po1-3-4.

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31

Shahidi, Fereidoon, and Anoma Chandrasekara. "Hydroxycinnamates and their in vitro and in vivo antioxidant activities." Phytochemistry Reviews 9, no. 1 (2009): 147–70. http://dx.doi.org/10.1007/s11101-009-9142-8.

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32

Domergue, Frédéric, and Dylan Kosma. "Occurrence and Biosynthesis of Alkyl Hydroxycinnamates in Plant Lipid Barriers." Plants 6, no. 4 (2017): 25. http://dx.doi.org/10.3390/plants6030025.

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33

Makris, Dimitris P. "Potato Processing Waste as a Reservoir of Bioactive Hydroxycinnamates: A Critical Review." Biomass 5, no. 1 (2024): 2. https://doi.org/10.3390/biomass5010002.

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Natural resources are currently overexploited to provide food supply for the ever-increasing world population, and because of the intensification of agricultural and food production, there is a growing rate of waste generation. This waste biomass is usually dumped into landfills, causing unprecedented damage to ecosystems. Nowadays, circular economy strategies are channeled towards waste harnessing, aiming at reducing the irrational use of resources and minimizing waste generation. Potatoes are the second largest food crop after cereals, and there is an overwhelming amount of waste derived fro

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34

Grajales-Hernández, Daniel A., Mariana A. Armendáriz-Ruiz, Fernando López Gallego, and Juan Carlos Mateos-Díaz. "Approaches for the enzymatic synthesis of alkyl hydroxycinnamates and applications thereof." Applied Microbiology and Biotechnology 105, no. 10 (2021): 3901–17. http://dx.doi.org/10.1007/s00253-021-11285-z.

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35

Choudhury, Ruksana, S. Kaila Srai, Edward Debnam, and Catherine A. Rice-Evans. "Urinary excretion of hydroxycinnamates and flavonoids after oral and intravenous administration." Free Radical Biology and Medicine 27, no. 3-4 (1999): 278–86. http://dx.doi.org/10.1016/s0891-5849(99)00054-4.

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36

Cremin, Peadar, Sidika Kasim-Karakas, and Andrew L. Waterhouse. "LC/ES−MS Detection of Hydroxycinnamates in Human Plasma and Urine." Journal of Agricultural and Food Chemistry 49, no. 4 (2001): 1747–50. http://dx.doi.org/10.1021/jf000764y.

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37

Shamilov, Arnold A., Daniil N. Olennikov, Dmitryi I. Pozdnyakov, Valentina N. Bubenchikova, Ekaterina R. Garsiya, and Mikhail V. Larskii. "Caucasian Blueberry: Comparative Study of Phenolic Compounds and Neuroprotective and Antioxidant Potential of Vaccinium myrtillus and Vaccinium arctostaphylos Leaves." Life 12, no. 12 (2022): 2079. http://dx.doi.org/10.3390/life12122079.

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(1) Background: Two Caucasian blueberries Vaccinium myrtillus L. and Vaccinium arctostaphylos L. are famous berry bushes growing in the Caucasus region and used to treat neurological diseases, but the chemistry and bioactivity of leaf extracts are still poorly studied. (2) Methods: Phenolic compounds of V. myrtillus and V. arctostaphylos leaf extracts were profiled and quantified by HPLC–PDA–ESI–tQ–MS. The neurotropic potential of Vaccinium extracts was studied using the model of middle cerebral artery permanent occlusion to determine cerebral blood flow, the area of the brain tissue necrosis,

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38

Williamson, G., A. J. Day, G. W. Plumb, and D. Couteau. "Human metabolic pathways of dietary flavonoids and cinnamates." Biochemical Society Transactions 28, no. 2 (2000): 16–22. http://dx.doi.org/10.1042/bst0280016.

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Flavonoids and cinnamates are widespread phenolic secondary metabolites synthesized by plants for defensive purposes. Many foods and beverages contain high levels of phenolic compounds. Certain phenolics in the diet are particularly bio-active and have pronounced effects on mammalian cells. These effects, together with epidemiological studies and animal models, have led to the hypothesis that dietary phenolics contribute to the health benefits of a diet rich in fruit and vegetables. This paper examines the biochemistry of the uptake and metabolic route of two groups of plant phenolics, the fla

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39

Ralph, John, Mirko Bunzel, Jane M. Marita, et al. "Peroxidase-dependent cross-linking reactions of p-hydroxycinnamates in plant cell walls." Phytochemistry Reviews 3, no. 1-2 (2004): 79–96. http://dx.doi.org/10.1023/b:phyt.0000047811.13837.fb.

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40

Weitkamp, Petra, Klaus Vosmann, and Nikolaus Weber. "Highly Efficient Preparation of Lipophilic Hydroxycinnamates by Solvent-free Lipase-Catalyzed Transesterification." Journal of Agricultural and Food Chemistry 54, no. 19 (2006): 7062–68. http://dx.doi.org/10.1021/jf0611973.

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41

Scordino, Monica, Alfio Di Mauro, Amedeo Passerini, and Emanuele Maccarone. "Selective Recovery of Anthocyanins and Hydroxycinnamates from a Byproduct of Citrus Processing." Journal of Agricultural and Food Chemistry 53, no. 3 (2005): 651–58. http://dx.doi.org/10.1021/jf048643b.

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42

Cho, Sung-Youl, Young-Kyu Song, Joong-Gon Kim, Se-Young Oh, and Chan-Moon Chung. "Photoconversion of o-hydroxycinnamates to coumarins and its application to fluorescence imaging." Tetrahedron Letters 50, no. 33 (2009): 4769–72. http://dx.doi.org/10.1016/j.tetlet.2009.06.031.

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43

Hatfield, R. D., and Jane M. Marita. "Enzymatic processes involved in the incorporation of hydroxycinnamates into grass cell walls." Phytochemistry Reviews 9, no. 1 (2010): 35–45. http://dx.doi.org/10.1007/s11101-010-9165-1.

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44

Bunzel, Mirko, Ella Allerdings, Volker Sinwell, John Ralph, and Hans Steinhart. "Cell wall hydroxycinnamates in wild rice ( Zizania aquatica L.) insoluble dietary fibre." European Food Research and Technology 214, no. 6 (2002): 482–88. http://dx.doi.org/10.1007/s00217-002-0512-3.

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45

Cevasco, Giorgio, and Sergio Thea. "Associative and Dissociative Pathways in the Alkaline Hydrolysis of Aryl 2-Hydroxycinnamates." Journal of Organic Chemistry 60, no. 1 (1995): 70–73. http://dx.doi.org/10.1021/jo00106a016.

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46

Olennikov, Daniil Nikolayevich, Nina Igorevna Kashchenko, and Nadezhda Konstantinovna Chirikova. "COMPOSITION AND BIOLOGICAL ACTIVITY OF FLAVONOIDS ANF HYDROXYCINNAMATES OF URTICA CANNABINA (URTICACEAE)." chemistry of plant raw material, no. 3 (September 26, 2022): 167–75. http://dx.doi.org/10.14258/jcprm.20220311231.

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Phenolic compounds of Urtica cannabina L. (cannabis nettle; family Urticaceae), a widespread Asian species of Russia, are poorly studied. In the present study, for the first time, a chromatographic analysis of U. cannabina growing in Eastern Siberia was realized together with isolation of flavonoids and hydroxycinnamates and study of the biological activity of extracts and pure compounds. As a result, it was found that the total extracts of U. cannabina were characterized by a high content of phenolic compounds and, as a result, a pronounced antiradical activity against DPPH• and ABTS•+ radica

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47

Vafiadi, Christina, Evangelos Topakas, Apostolos Alissandratos, Craig B. Faulds, and Paul Christakopoulos. "Enzymatic synthesis of butyl hydroxycinnamates and their inhibitory effects on LDL-oxidation." Journal of Biotechnology 133, no. 4 (2008): 497–504. http://dx.doi.org/10.1016/j.jbiotec.2007.11.004.

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48

Vèrette, Eric, Ann C. Noble, and T. Chris Somers. "Hydroxycinnamates ofVitis vinifera: Sensory assessment in relation to bitterness in white wines." Journal of the Science of Food and Agriculture 45, no. 3 (1988): 267–72. http://dx.doi.org/10.1002/jsfa.2740450310.

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49

Hubbard, Gary P., Siegfried Wolffram, Julie A. Lovegrove, and Jonathan M. Gibbins. "The role of polyphenolic compounds in the diet as inhibitors of platelet function." Proceedings of the Nutrition Society 62, no. 2 (2003): 469–78. http://dx.doi.org/10.1079/pns2003253.

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Platelets play a substantial role in cardiovascular disease, and for many years there has been a search for dietary components that are able to inhibit platelet function and therefore decrease the risk of cardiovascular disease. Platelets can be inhibited by alcohol, dietary fats and some antioxidants, including a group of compounds, the polyphenols, found in fruits and vegetables. A number of these compounds have been shown to inhibit platelet function both in vitro and in vivo. In the present study the effects of the hydroxycinnamates and the flavonoid quercetin on platelet activation and ce

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50

Rabiej-Kozioł, Dobrochna, Marek P. Krzemiński, and Aleksandra Szydłowska-Czerniak. "Synthesis of Steryl Hydroxycinnamates to Enhance Antioxidant Activity of Rapeseed Oil and Emulsions." Materials 13, no. 20 (2020): 4536. http://dx.doi.org/10.3390/ma13204536.

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Abstract:

In recent years, steryl esters have found potential applications in food, pharmaceutical and cosmetic industries. Therefore, three hydroxycinnamate steryl esters (HSEs): β-sitosteryl sinapate (β-SSA), β-sitosteryl caffeate (β-SCA), and β-sitosteryl ferulate (β-SFA) were synthesized by chemical approach and their antioxidant activity (AA) were analyzed by 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) assays. The values of inhibitory concentration (IC50) of each ester needed to inhibit 50% of the DPPH radical (IC50(DPPH) = 238.9, 78.3, 29

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