Relevant bibliographies by topics / Hydroxycoumarin derivative

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Hydroxycoumarin derivative'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Hydroxycoumarin derivative"

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BANI, TALAPATRA, Kumar Mandal Sudipta, Biswas Kallolmay, Chakrabarti Ramaprasad та K. Talapatra Sunil. "Reactions of 4-hydroxycoumarin with some α,β-unsaturated carbonyls and 1,3-dicarbonyls : trapping of 4-hydroxycoumarin tautomers; formation of a pimelic acid derivative and a novel bicyclo compound". Journal of Indian Chemical Society Vol. 78, Oct-Dec 2001 (2001): 765–71. https://doi.org/10.5281/zenodo.5910727.

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Centre of Advanced Studies on Natural Products, Department of Chemistry, University of Calcutta, University College of Science, 92, Acharya Praful la Chandra Road, Kolkata-700 009, India <em>E-mail</em> : talapatrask@yahoo.com <em>Manuscript received 31 August 2001</em> 4-Hydroxycoumarin (1) being endowed with both nucleophilic and electrophilic properties furnishes the dimeric coumarin derivative 3 in a pyridine catalyzed self-condensation process; while its attempted morpholine catalyzed self-condensation yields no dimeric coumarin derivative, but leads to the formation of the enamine deriva
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2

Bani, Talapatra, Kumar Mandal Sudipta, Biswas Kallolmay, Chakrabarti Ramaprasad, and K. Talapatra Sunil. "Reactions of 4-hydroxycoumarin with some a,J3-unsaturated carbonyls and 1,3-dicarbonyls: trapping of 4-hydroxycoumarin tautomers; formation of a pimelic acid derivative and a novel bicyclo compound." Journal of Indian Chemistry Society Vol. 78, October-December 2001 (2001): 765–71. https://doi.org/10.5281/zenodo.5901961.

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Centre of Advanced Studies on Natural Products, Department of Chemistry, University of Calcutta, University College of Science, 92, Acharya Prafulla Chandra Road, Kolkata-700 009, India <em>E-mail </em>: talapatrask@yahoo.com <em>Manuscript received 31 August 2001</em> 4-Hydroxycoumarin (1) being endowed with both nucleophilic and electrophilic properties furnishes the dimeric coumarin derivative 3 in a pyridine catalyzed self-condensation process; while its attempted morpholine catalyzed self-condensation yields no dimeric coumarin derivative, but leads to the formation of the enamine derivat
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Ristić, Milenko, Biljana Dekić, Niko Radulović, and Marija Aksić. "Synthesis, complete assignment of 1H- and 13C-NMR spectra and antioxidant activity of new azine derivative bearing coumarin moiety." Bulletin of Natural Sciences Research 11, no. 1 (2021): 9–16. http://dx.doi.org/10.5937/bnsr11-31265.

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In this research, the synthesis of a new azine derivative with coumarin moiety was performed in three reaction steps, starting from 4-hydroxycoumarin. The first step in synthesis was the acetylation of 4-hydroxycoumarin to yield 3-acetyl-4-hydroxycoumarin and then the obtained 3-acetyl-4-hydroxycoumarin was reacted with hydrazine hydrate and give a corresponding hydrazone. Condensation of the hydrazone with 4-ethoxy-3methoxybenzaldehyde afforded the target compound 1-[1-(4-hydroxy-2-oxo-2H-chromen-3-yl)-ethylidene]-2-(4etoxy-3-methoxybenzylidene)-hydrazine in a good yield. The resulting azine
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Szafraniec, Anna, and Waldemar Iwanek. "Intramolecular Hydrogen Bond Driven Conformational Selectivity of Coumarin Derivatives of Resorcin[4]arene." International Journal of Molecular Sciences 21, no. 17 (2020): 6160. http://dx.doi.org/10.3390/ijms21176160.

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In this study, the synthesis and structure of 4-aminocoumarin derivatives of resorcin[4]arene were investigated. Spectroscopic analysis and quantum mechanical calculations showed that this molecule undertakes a crown-in conformation in chloroform. The conformations of the aminocoumarin derivative of resorcin[4]arene were compared with a hydroxycoumarin derivative of resorcin[4]arene, and the effect of the substituent on the conformational selectivity of the coumarin derivatives of resorcin[4]arene was demonstrated. Both UV-VIS and fluorescence spectroscopy for the coumarin derivative of resorc
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Yoon, Jeong A., and Young Taek Han. "Efficient Synthesis of Pyrido[3,2-c]coumarins via Silver Nitrate Catalyzed Cycloisomerization and Application to the First Synthesis of Polyneomarline C." Synthesis 51, no. 24 (2019): 4611–18. http://dx.doi.org/10.1055/s-0037-1610730.

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Herein, we report an efficient method for the synthesis of the pyrido[3,2-c]coumarin scaffold, one of the privileged heterocycle-fused coumarin scaffolds, via a AgNO3-catalyzed cycloisomerization of 4-(propynylamino)coumarins obtained from diverse 4-hydroxycoumarins. This concise method affords pyrido[3,2-c]coumarin analogues bearing diverse substituents on the benzene or pyridine ring in moderate to good yields. Moreover, this methodology was extended to the facile synthesis of polyneomarline C, a natural pyrido[3,2-c]coumarin derivative isolated from the Chinese herbal medicine Polyalthia ne
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Dimić, Dušan S., Goran N. Kaluđerović, Edina H. Avdović, et al. "Synthesis, Crystallographic, Quantum Chemical, Antitumor, and Molecular Docking/Dynamic Studies of 4-Hydroxycoumarin-Neurotransmitter Derivatives." International Journal of Molecular Sciences 23, no. 2 (2022): 1001. http://dx.doi.org/10.3390/ijms23021001.

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In this contribution, four new compounds synthesized from 4-hydroxycoumarin and tyramine/octopamine/norepinephrine/3-methoxytyramine are characterized spectroscopically (IR and NMR), chromatographically (UHPLC-DAD), and structurally at the B3LYP/6-311++G*(d,p) level of theory. The crystal structure of the 4-hydroxycoumarin-octopamine derivative was solved and used as a starting geometry for structural optimization. Along with the previously obtained 4-hydroxycoumarin-dopamine derivative, the intramolecular interactions governing the stability of these compounds were quantified by NBO and QTAIM
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Traven, Valery F., Larisa I. Vorobjeva, Tatjana A. Chibisova, Edward Andrew Carberry, and Noelle Jean Beyer. "Electronic absorption spectra and structure of hydroxycoumarin derivatives and their ionized forms." Canadian Journal of Chemistry 75, no. 4 (1997): 365–76. http://dx.doi.org/10.1139/v97-042.

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Electronic absorption spectra of 18 hydroxycoumarin derivatives and their ionized forms have been studied. Close agreement between experimental and the PPP CI calculated electron absorption band energies has been found in most cases. Strong polarization of the carbonyl function of the pyrone ring in the 7-hydroxycoumarin derivatives, H-bonding between the hydroxyl group and neighboring substituent in the ortho-substituted hydroxycoumarins, as well as their tautomeric transformations, have been suggested in the discussion of the electronic absorption spectra of the hydroxycoumarin derivatives.
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8

Stanchev, Stancho, Frank Jensen, Anton Hinkov, et al. "Synthesis and Inhibiting Activity of Some 4-Hydroxycoumarin Derivatives on HIV-1 Protease." ISRN Pharmaceutics 2011 (July 26, 2011): 1–9. http://dx.doi.org/10.5402/2011/137637.

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Six novel 4-hydroxycoumarin derivatives were rationally synthesized, verified, and characterized by molecular docking using crystal HIV-1 protease. Molecular docking studies predicted antiprotease activity of (7) and (10). The most significant functional groups, responsible for the interaction with HIV-1 protease by hydrogen bonds formation are pyran oxygen, atom, lactone carbonyl oxygen and one of the hydroxyl groups. The newly synthesized compounds were biologically tested in MT-4 cells for inhibiting HIV-1 replication, exploring the protection of cells from the cytopathic effect of HIV meas
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Bhuyan, Pulak, Sinki Kolita, Leema Dutta, and Pankaj Das. "One-Pot Synthesis of Unsymmetrical Bis(4-Hydroxycoumarin-3-yl)methanes." Synlett 28, no. 17 (2017): 2291–94. http://dx.doi.org/10.1055/s-0036-1589065.

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Unsymmetrical bis(4-hydroxycoumarin-3-yl)methane derivatives have been synthesized from 4-hydroxycoumarins, aldehydes, and secondary amines via 3-(aminoalkyl)-4-hydroxycoumarin intermediates, followed by substitution.
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Zhang, Yuying, Xiaoyu Wang, and Dejun Zhou. "Synthesis and Antiallergic Activity of Dicoumarin Derivatives." Molecules 29, no. 16 (2024): 3799. http://dx.doi.org/10.3390/molecules29163799.

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Allergies are one of the diseases whose incidence rates have increased in recent years due to the greenhouse effect and extreme climate change. Therefore, the development of new antiallergic drugs has attracted the interest of researchers in chemistry and pharmacy fields. Dicoumarin is a coumarin derivative with various biological activities, but its antiallergic activity has not been evaluated. In this study, 14 different dicoumarin derivatives were synthesized by diethylamine-catalyzed condensation reactions of 4-hydroxycoumarin with 14 different aldehydes, and they were identified on the ba
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Dissertations / Theses on the topic "Hydroxycoumarin derivative"

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Lee, Lin-Wen, and 李玲玟. "Synthesis and antibacterial activities evaluation of 7-hydroxycoumarin and coumarin-3-carboxamide derivatives." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/00138070825567486921.

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碩士<br>臺北醫學大學<br>藥學系<br>92<br>Synthesis and antibacterial activities evaluation of 7-hydroxycoumarin and coumarin-3-carboxamide derivatives Coumarin is widely distributed in plants and the coumarin derivatives are used as fluorescence dye, laser dye, food additives and medicines at present. Nowadays coumarins are an important group of organic compounds that are used as anticoagulant (dicoumarol), antiviruses, antibacterial, antifungi, antitumor, antimutagenic, anti-inflammatory and antioxidant agents. It also use as prodrug in cartilage explants. The major metab
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Jhang, Jing-Fu, and 張景富. "Reactions of 4-hydroxycoumarins with 1-methyl quinolinium derivatives and their potential applications." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/60528096030079638268.

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碩士<br>東海大學<br>化學系<br>98<br>An oxazabicycle derivative 5a was efficiently synthesized by coupling of 7-dimethylamino-4-hydroxycoumarin 10 with N-methyl-2-phenylquinolinium iodide 18 and to investigate its fluorescence redox-switching properties. Chemical reduction of this strongly fluorescent oxazabicycle results in the ring-opened product with a distinct decrease in emission intensity. The resulting ring-opened species can be swiftly reverted to the original ring-closed forms by DDQ oxidation. A novel coumarin and phenanthridine-fused heterocycle and an oxazaspiropyran derivative 6a were also
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Liao, Yuan-Xiu, and 廖苑秀. "Efficient synthesis of trisubstituted[1]benzopyrano[4,3-b]pyrrol-4(1H)-one derivatives from 4-hydroxycoumarin and Design and synthesis oxazobicycle derivatives as potential organic photochromism." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/99603047632870553438.

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碩士<br>東海大學<br>化學系<br>92<br>Abstract Part I、Efficient synthesis of trisubstituted[1]benzopyrano[4,3-b] pyrrol-4(1H)-one derivatives from 4-hydroxycoumarin Various trisubstituted [1]benzopyrano[4,3-b]pyrrol-4(1H)-one derivatives have been synthesized from 4-hydroxycoumarin with a 30-40 % yield over six steps. The key step of the synthesis is a base- promoted intramolecular cyclization of enamines 5, followed by dehydration to generate the fused pyrrole ring. Abstract Part II、Design and synthesis oxazobicycle derivatives
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Huang, Chin-Neng, and 黃志能. "Part I、Design and synthesis of 3-(2-Phenyl-4H-thio-chromen-4-yildene)-3H-chromene-2,4-dione derivatives as potential redox switchesPart II、Design and Synthesis of 7-N,N-dimethylamino-4-hydroxycoumarin-based derivatives as potential organic photochromi." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/33645529616308159980.

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碩士<br>東海大學<br>化學系<br>95<br>Part I、Design and synthesis of 2'-phenyl-[3,4']bichromenylidene -2,4-dione derivatives as potential redox switching Tow 3-(2-Phenyl-4H-thiochromen-4-yildene)-3H-chromene-2,4-dione derivatives were synthesized in several steps from thiophenol and 4-hydroxycoumarins with overall yields of 65 and 67%. The prepared compounds 16 and 21 instantly changed from either purple or bule to colorless when treated them with sodium borohydride in methanol. The resulting reduced compounds reverted to their original colors after the reducing agent was removed. While no fluorescence
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Book chapters on the topic "Hydroxycoumarin derivative"

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Kaur, Jaskiran, Paras Famta, Navneet Khurana, Manish Vyas, and Gopal L. Khatik. "Biomedical applications of 4-hydroxycoumarin as a fungal metabolite and its derivatives." In New and Future Developments in Microbial Biotechnology and Bioengineering. Elsevier, 2020. http://dx.doi.org/10.1016/b978-0-12-821006-2.00016-9.

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Conference papers on the topic "Hydroxycoumarin derivative"

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Dimić, Dušan, Dejan Milenković, Edina Avdović, Goran Kaluđerović, and Jasmina Dimitrić Marković. "MOLECULAR DOCKING AND MOLECULAR DYNAMICS STUDIES OF THE INTERACTION BETWEEN COUMARIN-NEUROTRANSMITTER DERIVATIVES AND CARBONIC ANHYDRASE IX." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac,, 2021. http://dx.doi.org/10.46793/iccbi21.056d.

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Novel biologically active compounds can be obtained by the structural modification of coumarins. In this contribution, five new derivatives of 4-hydroxycoumarin with tyramine, octopamine, norepinephrine, 3-methoxytyramine, and dopamine were obtained. Their structures were optimized based on the previously obtained crystal structure of the 4-hydroxycoumarin-dopamine derivative. The special emphasis was put on the effect of various substituents on the structure of obtained compounds and intramolecular interactions governing the stability. To investigate their possible antitumor activity, molecul
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Kurjan, Jakub, Rastislav Jendželovský, Zuzana Jendželovská, et al. "A novel silver complex with 4-hydroxycoumarin derivative: Synthesis, structure, and biological activity." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.447k.

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In this contribution, a novel coumarin-derivative ligand, and its silver(I) complex are reported. Ligand 3-(1-(2-pyridylamino)ethylidene)-2H-chromene-2,4-dione (HL) was prepared by reaction of 3-acetyl-4-hydroxycoumarin with 2-picolyl amine. Further, complex [Ag(HL)2]NO3 was prepared and both compounds were characterized by physico-chemical methods such as IR and NMR spectroscopy, elemental analysis, and structure of the ligand and the complex was confirmed by X-ray analysis. The stability of both compounds was measured by NMR spectroscopy. MTT assay and cell proliferation assay on human lung
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Avdović, Edina, Sandra Jovičić Milić, Dušica Simijonović, Danijela Stojković, Dejan Milenković, and Zoran Marković. "SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION AND BSA INTERACTIONS OF 3-(1-((4-HYDROXY PENTYLAMINO)ETHYLIDENE)CHROMAN-2,4-DIONE." In 17th International Conference on Fundamental and Applied Aspects of Physical Chemistry. Society of Physical Chemists of Serbia, 2024. https://doi.org/10.46793/phys.chem24i.053a.

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In this study, we synthesized a novel coumarin derivative, specifically 3-(1-((4-hydroxy pentylamino)ethylidene)cromane-2,4-dione by the reaction of 3-acetyl-4-hydroxycoumarin and 5- aminopentanol in methanol. The compound was obtained after 2 hours of reflux. The synthesized coumarin derivative was obtained in very good yield (80%) and characterized using elemental microanalysis, Uv-Vis, IR and NMR spectroscopy. Furthermore, the interaction of investigated compound with bovine serum albumin (BSA) was studied using fluorescence spectroscopy and the Stern-Volmer constant (Ksv), quenching rate c
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