Academic literature on the topic 'HYDROXYCOUMARIN DERIVATIVES'

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Journal articles on the topic "HYDROXYCOUMARIN DERIVATIVES"

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Traven, Valery F., Larisa I. Vorobjeva, Tatjana A. Chibisova, Edward Andrew Carberry, and Noelle Jean Beyer. "Electronic absorption spectra and structure of hydroxycoumarin derivatives and their ionized forms." Canadian Journal of Chemistry 75, no. 4 (1997): 365–76. http://dx.doi.org/10.1139/v97-042.

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Electronic absorption spectra of 18 hydroxycoumarin derivatives and their ionized forms have been studied. Close agreement between experimental and the PPP CI calculated electron absorption band energies has been found in most cases. Strong polarization of the carbonyl function of the pyrone ring in the 7-hydroxycoumarin derivatives, H-bonding between the hydroxyl group and neighboring substituent in the ortho-substituted hydroxycoumarins, as well as their tautomeric transformations, have been suggested in the discussion of the electronic absorption spectra of the hydroxycoumarin derivatives.
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Bhuyan, Pulak, Sinki Kolita, Leema Dutta, and Pankaj Das. "One-Pot Synthesis of Unsymmetrical Bis(4-Hydroxycoumarin-3-yl)methanes." Synlett 28, no. 17 (2017): 2291–94. http://dx.doi.org/10.1055/s-0036-1589065.

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Unsymmetrical bis(4-hydroxycoumarin-3-yl)methane derivatives have been synthesized from 4-hydroxycoumarins, aldehydes, and secondary amines via 3-(aminoalkyl)-4-hydroxycoumarin intermediates, followed by substitution.
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Wu, Nan, Xinnian Li, Xin Xu, and Daqing Shi. "Synthesis of 3,3′-arylmethylidenebis-4-hydroxycoumarin derivatives catalysed by KF-montmorillonite." Journal of Chemical Research 2007, no. 10 (2007): 561–62. http://dx.doi.org/10.3184/030823407x255551a.

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3,3′-Arylmethylidenebis-4-hydroxycoumarins derivatives have been synthesised in good yields by the Michael addition reaction of aromatic aldehydes with 4-hydroxycoumarin in DMF catalysed by KF-montmorillonite.
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Završnik, Davorka, Samija Muratović, Selma Špirtović, Dženita Softić, and Marica Medić-Šarić. "The Synthesis and Antimicrobial Activity of Some 4-Hydroxycoumarin Derivatives." Bosnian Journal of Basic Medical Sciences 8, no. 3 (2008): 277–81. http://dx.doi.org/10.17305/bjbms.2008.2933.

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Due to exceptional reactivity of 4-hydroxycoumarin, the synthesis of new coumarin derivatives of dimer and tetramer type has been carried out. The synthesis was carried out from 4-hydroxycoumarin and various aromatic aldehydes. In this way, compounds of the dimer 3,3’-(benzilidene)bis (4-hydroxycoumarin) type, as well as of the tetramer 3,3,’3’,’3’’’-(1,4-dim- ethylenphenyl)tetra (4-hydroxycoumarin) type were prepared.The newly synthesized derivatives contain different functional groups, and as such they could exhibit microbiological activity. Therefore, we tested the microbiological activity
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BANI, TALAPATRA, Kumar Mandal Sudipta, Biswas Kallolmay, Chakrabarti Ramaprasad та K. Talapatra Sunil. "Reactions of 4-hydroxycoumarin with some α,β-unsaturated carbonyls and 1,3-dicarbonyls : trapping of 4-hydroxycoumarin tautomers; formation of a pimelic acid derivative and a novel bicyclo compound". Journal of Indian Chemical Society Vol. 78, Oct-Dec 2001 (2001): 765–71. https://doi.org/10.5281/zenodo.5910727.

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Centre of Advanced Studies on Natural Products, Department of Chemistry, University of Calcutta, University College of Science, 92, Acharya Praful la Chandra Road, Kolkata-700 009, India <em>E-mail</em> : talapatrask@yahoo.com <em>Manuscript received 31 August 2001</em> 4-Hydroxycoumarin (1) being endowed with both nucleophilic and electrophilic properties furnishes the dimeric coumarin derivative 3 in a pyridine catalyzed self-condensation process; while its attempted morpholine catalyzed self-condensation yields no dimeric coumarin derivative, but leads to the formation of the enamine deriva
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Bani, Talapatra, Kumar Mandal Sudipta, Biswas Kallolmay, Chakrabarti Ramaprasad, and K. Talapatra Sunil. "Reactions of 4-hydroxycoumarin with some a,J3-unsaturated carbonyls and 1,3-dicarbonyls: trapping of 4-hydroxycoumarin tautomers; formation of a pimelic acid derivative and a novel bicyclo compound." Journal of Indian Chemistry Society Vol. 78, October-December 2001 (2001): 765–71. https://doi.org/10.5281/zenodo.5901961.

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Centre of Advanced Studies on Natural Products, Department of Chemistry, University of Calcutta, University College of Science, 92, Acharya Prafulla Chandra Road, Kolkata-700 009, India <em>E-mail </em>: talapatrask@yahoo.com <em>Manuscript received 31 August 2001</em> 4-Hydroxycoumarin (1) being endowed with both nucleophilic and electrophilic properties furnishes the dimeric coumarin derivative 3 in a pyridine catalyzed self-condensation process; while its attempted morpholine catalyzed self-condensation yields no dimeric coumarin derivative, but leads to the formation of the enamine derivat
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Abu-Eittah, Rafie H., and Bahgat Ali H. El-Tawil. "The electronic absorption spectra of some coumarins. A molecular orbital treatment." Canadian Journal of Chemistry 63, no. 6 (1985): 1173–79. http://dx.doi.org/10.1139/v85-200.

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The electronic absorption spectra of coumarin and its derivatives umbelliferone (6-hydroxycoumarin), esculetin (6,7-dihydroxycoumarin), and scopoletin (6-methoxy-7-hydroxycoumarin) were investigated. The n → π* transition was not observed in the spectrum of coumarin but was observed in the spectra of some of its derivatives. Molecular orbital calculations, using the INDO procedures, were carried out on coumarin and some of its derivatives. The activities of the different sites of the molecules are discussed in terms of the coefficients of the atomic orbitals constituting the HOMO and the LUMO.
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S., M. DESAI, та N. TRIVEDI K. "Synthesis of 3-Substituted-aminopropoxy-2'-hydroxycoumarin Derivatives as Possible β-Blockers". Journal Of Indian Chemical Society Vol. 66, Jun 1989 (1989): 415–17. https://doi.org/10.5281/zenodo.6155572.

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Department of Chemistry, Faculty of Science, M.S. University&nbsp;of Baroda, Baroda-390 002 Manuscript received 26 July 1988, revised 24 January&nbsp;1989,&nbsp;accepted&nbsp;31 March 1989 Synthesis of 3-Substituted-aminopropoxy-2&#39;-hydroxycoumarin Derivatives as Possible &beta;-Blockers &nbsp;
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Szafraniec, Anna, and Waldemar Iwanek. "Intramolecular Hydrogen Bond Driven Conformational Selectivity of Coumarin Derivatives of Resorcin[4]arene." International Journal of Molecular Sciences 21, no. 17 (2020): 6160. http://dx.doi.org/10.3390/ijms21176160.

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In this study, the synthesis and structure of 4-aminocoumarin derivatives of resorcin[4]arene were investigated. Spectroscopic analysis and quantum mechanical calculations showed that this molecule undertakes a crown-in conformation in chloroform. The conformations of the aminocoumarin derivative of resorcin[4]arene were compared with a hydroxycoumarin derivative of resorcin[4]arene, and the effect of the substituent on the conformational selectivity of the coumarin derivatives of resorcin[4]arene was demonstrated. Both UV-VIS and fluorescence spectroscopy for the coumarin derivative of resorc
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K., N. Trivedi, S. Madhava Rao S., V. Mistry S., and M. Desai S. "Chemistry of 4-hydroxycoumarin." Journal of Indian Chemical Society Vol. 78, Oct-Dec 2001 (2001): 579–95. https://doi.org/10.5281/zenodo.5910204.

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Department of Chemistry, Faculty of Science, M.S. University of Baroda, Vadodara-390 002, India E-mail: samir2sam@yahoo.com <em>Manuscript received 22 December 2000</em> 4-Hydroxycoumarin, a highly reactive compound, is reviewed with respect to its synthesis, tautomerism, reactions and structure-activity relationship of its derivatives for anticoagulant property.
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Dissertations / Theses on the topic "HYDROXYCOUMARIN DERIVATIVES"

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Lee, Lin-Wen, and 李玲玟. "Synthesis and antibacterial activities evaluation of 7-hydroxycoumarin and coumarin-3-carboxamide derivatives." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/00138070825567486921.

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碩士<br>臺北醫學大學<br>藥學系<br>92<br>Synthesis and antibacterial activities evaluation of 7-hydroxycoumarin and coumarin-3-carboxamide derivatives Coumarin is widely distributed in plants and the coumarin derivatives are used as fluorescence dye, laser dye, food additives and medicines at present. Nowadays coumarins are an important group of organic compounds that are used as anticoagulant (dicoumarol), antiviruses, antibacterial, antifungi, antitumor, antimutagenic, anti-inflammatory and antioxidant agents. It also use as prodrug in cartilage explants. The major metab
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Liao, Yuan-Xiu, and 廖苑秀. "Efficient synthesis of trisubstituted[1]benzopyrano[4,3-b]pyrrol-4(1H)-one derivatives from 4-hydroxycoumarin and Design and synthesis oxazobicycle derivatives as potential organic photochromism." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/99603047632870553438.

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碩士<br>東海大學<br>化學系<br>92<br>Abstract Part I、Efficient synthesis of trisubstituted[1]benzopyrano[4,3-b] pyrrol-4(1H)-one derivatives from 4-hydroxycoumarin Various trisubstituted [1]benzopyrano[4,3-b]pyrrol-4(1H)-one derivatives have been synthesized from 4-hydroxycoumarin with a 30-40 % yield over six steps. The key step of the synthesis is a base- promoted intramolecular cyclization of enamines 5, followed by dehydration to generate the fused pyrrole ring. Abstract Part II、Design and synthesis oxazobicycle derivatives
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Huang, Chin-Neng, and 黃志能. "Part I、Design and synthesis of 3-(2-Phenyl-4H-thio-chromen-4-yildene)-3H-chromene-2,4-dione derivatives as potential redox switchesPart II、Design and Synthesis of 7-N,N-dimethylamino-4-hydroxycoumarin-based derivatives as potential organic photochromi." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/33645529616308159980.

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碩士<br>東海大學<br>化學系<br>95<br>Part I、Design and synthesis of 2'-phenyl-[3,4']bichromenylidene -2,4-dione derivatives as potential redox switching Tow 3-(2-Phenyl-4H-thiochromen-4-yildene)-3H-chromene-2,4-dione derivatives were synthesized in several steps from thiophenol and 4-hydroxycoumarins with overall yields of 65 and 67%. The prepared compounds 16 and 21 instantly changed from either purple or bule to colorless when treated them with sodium borohydride in methanol. The resulting reduced compounds reverted to their original colors after the reducing agent was removed. While no fluorescence
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Jhang, Jing-Fu, and 張景富. "Reactions of 4-hydroxycoumarins with 1-methyl quinolinium derivatives and their potential applications." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/60528096030079638268.

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碩士<br>東海大學<br>化學系<br>98<br>An oxazabicycle derivative 5a was efficiently synthesized by coupling of 7-dimethylamino-4-hydroxycoumarin 10 with N-methyl-2-phenylquinolinium iodide 18 and to investigate its fluorescence redox-switching properties. Chemical reduction of this strongly fluorescent oxazabicycle results in the ring-opened product with a distinct decrease in emission intensity. The resulting ring-opened species can be swiftly reverted to the original ring-closed forms by DDQ oxidation. A novel coumarin and phenanthridine-fused heterocycle and an oxazaspiropyran derivative 6a were also
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Book chapters on the topic "HYDROXYCOUMARIN DERIVATIVES"

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Kaur, Jaskiran, Paras Famta, Navneet Khurana, Manish Vyas, and Gopal L. Khatik. "Biomedical applications of 4-hydroxycoumarin as a fungal metabolite and its derivatives." In New and Future Developments in Microbial Biotechnology and Bioengineering. Elsevier, 2020. http://dx.doi.org/10.1016/b978-0-12-821006-2.00016-9.

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Conference papers on the topic "HYDROXYCOUMARIN DERIVATIVES"

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Dimić, Dušan, Dejan Milenković, Edina Avdović, Goran Kaluđerović, and Jasmina Dimitrić Marković. "MOLECULAR DOCKING AND MOLECULAR DYNAMICS STUDIES OF THE INTERACTION BETWEEN COUMARIN-NEUROTRANSMITTER DERIVATIVES AND CARBONIC ANHYDRASE IX." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac,, 2021. http://dx.doi.org/10.46793/iccbi21.056d.

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Novel biologically active compounds can be obtained by the structural modification of coumarins. In this contribution, five new derivatives of 4-hydroxycoumarin with tyramine, octopamine, norepinephrine, 3-methoxytyramine, and dopamine were obtained. Their structures were optimized based on the previously obtained crystal structure of the 4-hydroxycoumarin-dopamine derivative. The special emphasis was put on the effect of various substituents on the structure of obtained compounds and intramolecular interactions governing the stability. To investigate their possible antitumor activity, molecul
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Kurjan, Jakub, Rastislav Jendželovský, Zuzana Jendželovská, et al. "A novel silver complex with 4-hydroxycoumarin derivative: Synthesis, structure, and biological activity." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.447k.

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In this contribution, a novel coumarin-derivative ligand, and its silver(I) complex are reported. Ligand 3-(1-(2-pyridylamino)ethylidene)-2H-chromene-2,4-dione (HL) was prepared by reaction of 3-acetyl-4-hydroxycoumarin with 2-picolyl amine. Further, complex [Ag(HL)2]NO3 was prepared and both compounds were characterized by physico-chemical methods such as IR and NMR spectroscopy, elemental analysis, and structure of the ligand and the complex was confirmed by X-ray analysis. The stability of both compounds was measured by NMR spectroscopy. MTT assay and cell proliferation assay on human lung
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Avdović, Edina, Sandra Jovičić Milić, Dušica Simijonović, Danijela Stojković, Dejan Milenković, and Zoran Marković. "SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION AND BSA INTERACTIONS OF 3-(1-((4-HYDROXY PENTYLAMINO)ETHYLIDENE)CHROMAN-2,4-DIONE." In 17th International Conference on Fundamental and Applied Aspects of Physical Chemistry. Society of Physical Chemists of Serbia, 2024. https://doi.org/10.46793/phys.chem24i.053a.

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In this study, we synthesized a novel coumarin derivative, specifically 3-(1-((4-hydroxy pentylamino)ethylidene)cromane-2,4-dione by the reaction of 3-acetyl-4-hydroxycoumarin and 5- aminopentanol in methanol. The compound was obtained after 2 hours of reflux. The synthesized coumarin derivative was obtained in very good yield (80%) and characterized using elemental microanalysis, Uv-Vis, IR and NMR spectroscopy. Furthermore, the interaction of investigated compound with bovine serum albumin (BSA) was studied using fluorescence spectroscopy and the Stern-Volmer constant (Ksv), quenching rate c
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