Academic literature on the topic 'Hydroxycoumarins'

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Journal articles on the topic "Hydroxycoumarins"

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Bhuyan, Pulak, Sinki Kolita, Leema Dutta, and Pankaj Das. "One-Pot Synthesis of Unsymmetrical Bis(4-Hydroxycoumarin-3-yl)methanes." Synlett 28, no. 17 (2017): 2291–94. http://dx.doi.org/10.1055/s-0036-1589065.

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Unsymmetrical bis(4-hydroxycoumarin-3-yl)methane derivatives have been synthesized from 4-hydroxycoumarins, aldehydes, and secondary amines via 3-(aminoalkyl)-4-hydroxycoumarin intermediates, followed by substitution.
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Traven, Valery F., Larisa I. Vorobjeva, Tatjana A. Chibisova, Edward Andrew Carberry, and Noelle Jean Beyer. "Electronic absorption spectra and structure of hydroxycoumarin derivatives and their ionized forms." Canadian Journal of Chemistry 75, no. 4 (1997): 365–76. http://dx.doi.org/10.1139/v97-042.

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Electronic absorption spectra of 18 hydroxycoumarin derivatives and their ionized forms have been studied. Close agreement between experimental and the PPP CI calculated electron absorption band energies has been found in most cases. Strong polarization of the carbonyl function of the pyrone ring in the 7-hydroxycoumarin derivatives, H-bonding between the hydroxyl group and neighboring substituent in the ortho-substituted hydroxycoumarins, as well as their tautomeric transformations, have been suggested in the discussion of the electronic absorption spectra of the hydroxycoumarin derivatives.
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Anary-Abbasinejad, Mohammad, Hossein Anaraki-Ardakani, Azimeh Saidipoor, and Mahmood Shojaee. "Synthesis of 3-[(acetylamino)(aryl)methyl]-4-Hydroxycoumarins." Journal of Chemical Research 2007, no. 9 (2007): 535–37. http://dx.doi.org/10.3184/030823407x247785.

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One-pot, three-component reaction between aryl aldehydes, 4-hydroxycoumarin, and acetonitrile in the presence of chlorosulfonic acid affords 3-[(acetylamino)(aryl)methyl]-4-hydroxycoumarins in excellent yields.
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Wu, Nan, Xinnian Li, Xin Xu, and Daqing Shi. "Synthesis of 3,3′-arylmethylidenebis-4-hydroxycoumarin derivatives catalysed by KF-montmorillonite." Journal of Chemical Research 2007, no. 10 (2007): 561–62. http://dx.doi.org/10.3184/030823407x255551a.

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3,3′-Arylmethylidenebis-4-hydroxycoumarins derivatives have been synthesised in good yields by the Michael addition reaction of aromatic aldehydes with 4-hydroxycoumarin in DMF catalysed by KF-montmorillonite.
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ALOK, KUMAR MITRA, DE APARNA, KARCHAUDHURI NILAY, KUMAR MISRA SWAPAN, and KUMAR MUKHOPADHYAY APURBA. "Synthesis of Coumarins in Search of Better Nonpeptidic HIV Protease Inhibitors." Journal of Indian Chemical Society Vol. 75, Oct-Dec 1998 (1998): 666–71. https://doi.org/10.5281/zenodo.5916038.

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Department of Chemistry, University of Calcutta, 92, Acharya Prafulla Chandra Road, Calcutta-700 009 <em>Manuscript received 7 August 1998</em> 3-Substituted-4-hydroxycoumarins have been recently identified as active nonpeptidic HIV protease inhibitors. In order to get more potent inhibitors, synthesis of a number of 3-substituted-4-hydroxycoumarins have been designed. Nucleophilicity of C-3 in 4- hydroxycoum arin is exploited by reacting with an electrophile 3-carbethoxycoumarin to achieve a new C-3 substituted-4-hydroxycoumarin. But the product identified is a benzopyranodicoumarin (2), whic
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Anary-Abbasinejad, Mohammad, Khadijeh Charkhati, and Alireza Hassanabadi. "Stereoselective synthesis of 3-[2-(dialkoxyphosphoryl)-1,2-dialkoxycarbonyl-ethyl]-4-hydroxycoumarins by reaction between trialkyl phosphites, dialkyl acetylenedicarboxylates and 4-hydroxycoumarin." Journal of Chemical Research 2009, no. 5 (2009): 319–21. http://dx.doi.org/10.3184/030823409x450435.

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A three-component reaction between trialkyl phosphites, dialkyl acetylenedicarboxylates and 4-hydroxycoumarin is described as a simple and efficient route for the synthesis of 3-[2-(dialkoxyphosphoryl)-1,2-dialkoxycarbonyl-ethyl]-4-hydroxycoumarins in high yields.
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Yoon, Jeong A., and Young Taek Han. "Efficient Synthesis of Pyrido[3,2-c]coumarins via Silver Nitrate Catalyzed Cycloisomerization and Application to the First Synthesis of Polyneomarline C." Synthesis 51, no. 24 (2019): 4611–18. http://dx.doi.org/10.1055/s-0037-1610730.

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Herein, we report an efficient method for the synthesis of the pyrido[3,2-c]coumarin scaffold, one of the privileged heterocycle-fused coumarin scaffolds, via a AgNO3-catalyzed cycloisomerization of 4-(propynylamino)coumarins obtained from diverse 4-hydroxycoumarins. This concise method affords pyrido[3,2-c]coumarin analogues bearing diverse substituents on the benzene or pyridine ring in moderate to good yields. Moreover, this methodology was extended to the facile synthesis of polyneomarline C, a natural pyrido[3,2-c]coumarin derivative isolated from the Chinese herbal medicine Polyalthia ne
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Kostova, Ivanka. "Hydroxycoumarins fromFraxinus ornusBark." Planta Medica 58, no. 05 (1992): 484. http://dx.doi.org/10.1055/s-2006-961529.

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Timonen, Juri, Paula Aulaskari, Pipsa Hirva, and Pirjo Vainiotalo. "Negative Ion Electrospray Ionization Mass Spectrometry and Computational Studies on Substituted 7-Hydroxycoumarins." European Journal of Mass Spectrometry 15, no. 5 (2009): 595–603. http://dx.doi.org/10.1255/ejms.1019.

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Twenty-two substituted 7-hydroxycoumarins were studied by negative ion electrospray ionization collision-induced dissociation (CID) mass spectrometry. Fragmentation pathways were also investigated by computation method using the B3LYP density functional theory. In general, the most important fragmentations of the 7-hydroxycoumarin [M – H]− ions were the elimination of CO2 and CO which agreed with the calculated energies of the proposed fragmentation reactions. In most cases, methyl group elimination was also favorable. Methyl group elimination occurred in three different ways, the most interes
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Datta, Mrityunjoy. "Synthesis of Linear 6-Allylated-7-hydroxycoumarins: para-Claisen Rearrangement of 2'-Allylated/Prenylated Derivatives of 4'-Prenyloxy Cinnamic Acid." Asian Journal of Chemistry 37, no. 1 (2024): 100–104. https://doi.org/10.14233/ajchem.2025.32937.

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Linear 6-allylated-7-hydroxycoumarins were synthesized by the para-Claisen rearrangement of 4'-prenyloxy cinnamic acid derivatives under refluxing condition in N,N-diethylaniline. This method eliminates the requirement for an additional Lewis acid, such as boron trifluoride etherate or trichloride, to convert 7-alkoxycoumarins into 7-hydroxycoumarins, unlike alternative techniques.
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Dissertations / Theses on the topic "Hydroxycoumarins"

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Alhalaseh, Lidia. "Phytochemistry of hydroxycoumarins from Manihot esculenta Euphorbiaceae (cassava)." Thesis, University of Bath, 2017. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.725401.

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This is an interdisciplinary research project on cassava (Manihot esculenta Crantz, Euphorbiaceae) ultimately working towards producing cassava roots which are long-lasting, free of post-harvest physiological deterioration (PPD). It aims to contribute to ensuring food security. In cassava, scopoletin and its -glycoside scopolin are considered phytoanticipants, not phytoalexins, due to their increasing accumulation during the PPD process compared to their barely detectable levels in fresh roots. Starting with a focussed literature review on the potential of cassava, contrasted with its limitat
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Boulven, Manon. "Conception, synthèse et évaluation biologique de nouveaux composés hétérocycliques anticoagulants à usage rodonticide." Thesis, Lyon, 2016. http://www.theses.fr/2016LYSEI106.

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A ce jour, les anticoagulants commerciaux souffrent de deux inconvénients majeurs : leur rémanence avec, pour certains d’entre eux, une demi-vie hépatique proche des 300 jours causant des intoxications secondaires sur les prédateurs des rongeurs, ainsi que le développement de nombreuses mutations génétiques causé par l’utilisation intensive de ces composés, rendant inopérant l’utilisation de certains AVKs commerciaux. Face à ce constat, l’Union Européenne envisage d’interdire l’utilisation de tels composés. La mission prioritaire est donc de trouver un anticoagulant capable de gérer les popula
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Bayoumi, Soad Abdel Latief Hassan. "Molecular genetic analysis of secondary metabolite biosynthesis in cassava as an economic and nutritious plant." Thesis, University of Bath, 2008. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.512260.

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Cassava (Manihot esculenta Crantz Family Euphorbiaceae) is an important tropical food crop. However, harvested cassava roots have a shelf-life of only days due to post-harvest physiological deterioration (PPD). Within 1-3 days of harvesting, the roots show blue-black vascular streaking and are unpalatable. PPD includes altered gene expression and the accumulation of hydroxycoumarin secondary metabolites, e.g. scopoletin and esculetin, and their respective glucosides scopolin and esculin. In this research several important aspects of the biosynthesis of these phytochemically important hydroxyco
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Montagut-Romans, Adrien. "Réactivité et pharmacomodulation de la 4-hydroxycoumarine : conception, synthèse et évaluation biologique de nouvelles molécules rodonticides éco-compatibles." Thesis, Lyon 1, 2014. http://www.theses.fr/2014LYO10028.

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L'usage des pesticides au sein de l'Union européenne est de plus en plus réglementé, et les rodonticides actuellement disponibles sur le marché sont responsables de nombreuses intoxications secondaires chez les prédateurs des rongeurs. Il est donc crucial aujourd'hui de trouver une alternative plus écologique aux molécules commerciales. Les travaux de recherches décrits dans cette thèse s'inscrivent dans ce contexte et présentent la mise au point de nouvelles voies d'accès à des structures coumariniques et leurs études biologiques. La molécule anticoagulante ciblée se devait d'être active sur
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Fergusson, D. "The effects of 4-hydroxycoumarin anticoagulant rodenticides on birds and the development of techniques for non-destructively monitoring their ecotoxicological effect." Thesis, University of Reading, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239503.

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Jhang, Jing-Fu, and 張景富. "Reactions of 4-hydroxycoumarins with 1-methyl quinolinium derivatives and their potential applications." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/60528096030079638268.

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碩士<br>東海大學<br>化學系<br>98<br>An oxazabicycle derivative 5a was efficiently synthesized by coupling of 7-dimethylamino-4-hydroxycoumarin 10 with N-methyl-2-phenylquinolinium iodide 18 and to investigate its fluorescence redox-switching properties. Chemical reduction of this strongly fluorescent oxazabicycle results in the ring-opened product with a distinct decrease in emission intensity. The resulting ring-opened species can be swiftly reverted to the original ring-closed forms by DDQ oxidation. A novel coumarin and phenanthridine-fused heterocycle and an oxazaspiropyran derivative 6a were also
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Lee, Lin-Wen, and 李玲玟. "Synthesis and antibacterial activities evaluation of 7-hydroxycoumarin and coumarin-3-carboxamide derivatives." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/00138070825567486921.

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碩士<br>臺北醫學大學<br>藥學系<br>92<br>Synthesis and antibacterial activities evaluation of 7-hydroxycoumarin and coumarin-3-carboxamide derivatives Coumarin is widely distributed in plants and the coumarin derivatives are used as fluorescence dye, laser dye, food additives and medicines at present. Nowadays coumarins are an important group of organic compounds that are used as anticoagulant (dicoumarol), antiviruses, antibacterial, antifungi, antitumor, antimutagenic, anti-inflammatory and antioxidant agents. It also use as prodrug in cartilage explants. The major metab
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"Protein Design and Engineering Using the Fluorescent Non-canonical Amino Acid L-(7-hydroxycoumarin-4-yl)ethylglycine." Doctoral diss., 2020. http://hdl.handle.net/2286/R.I.63009.

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abstract: Proteins are, arguably, the most complicated molecular machines found in nature. From the receptor proteins that decorate the exterior of cell membranes to enzymes that catalyze the slowest of chemical reactions, proteins perform a wide variety of essential biological functions. A reductionist view of proteins as a macromolecular group, however, may hold that they simply interact with other chemical species. Notably, proteins interact with other proteins, other biological macromolecules, small molecules, and ions. This in turn makes proteins uniquely qualified for use technological u
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Chen, Tzu Chun, and 陳姿均. "Ultrafast time-resolved fluorescence studies of Excited-State Proton Transfer Dynamics in 3-cyano-4-methyl-7-hydroxycoumarin complexes." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/67587882491110745079.

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碩士<br>國立清華大學<br>化學系<br>104<br>We employed a broadband ultrafast time-resolved fluorescence (TRFL) spectrometer implemented by optical Kerr gating (OKG) to study the excited-state proton transfer (ESPT) dynamics in 3-cyano-4-methyl-7-hydroxycoumarin (3CN4MU) complexes. We chose 3CN4MU as the proton donor and two bases, triethylamine (TEA) and 1-methylimidazole (1MI), of different proton affinities (PA) as the proton acceptors. We used two solvents, ethyl acetate (EA) and toluene (TL), of different polarities to study the solvent effect in ESPT. It was conclude from by steady-state spectra that
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Wu, Nien-Hsun, and 吳念勳. "Excited-State Proton Transfer Reaction in 3-Cyano-4-Methyl-7-Hydroxycoumarin Complexes Studied by Femtosecond Time-resolved Fluorescence Spectroscopy." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/6xbce8.

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碩士<br>國立清華大學<br>化學系所<br>105<br>We studied intermolecular excited-state proton transfer (ESPT) dynamics in hydrogen-bonded complexes of 3-cyano-4-methyl-7-hydroxycoumarin (3CN4MU) by using steady-state absorption/fluorescence spectroscopy and ultrafast time-resolved optical Kerr gating fluorescence spectroscopy. Two different proton acceptors, 1-methyl imidazole (1MI) and triethylamine (TEA), were studied, and the experiments were carried out in strong- and weak-polarity solvents. We also carried out density-functional-theory (DFT) calculations to help us interpreting the experimental results.
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Books on the topic "Hydroxycoumarins"

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Manolov, Ilia. Synthesis and Structure of Some 4-Hydroxycoumarins and Their Pharmacological Activity. Cambridge Scholars Publishing, 2023.

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Brodifacoum Health and Safety Guide (Health & Safety Guide: 93). World Health Organization, 1995.

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Bromadiolone Health and Safety Guide (Health & Safety Guide: 94). World Health Organization, 1995.

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Difenacoum Health and Safety Guide (Health & Safety Guide: 95). World Health Organization, 1995.

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Book chapters on the topic "Hydroxycoumarins"

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Gainor, J. A., T. D. Gordon, and B. A. Morgan. "The synthesis and coupling efficiency of 7-hydroxycoumarin-4-propionic acid, a fluorescent marker useful in immobilized substrate libraries." In Peptides. Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-011-0683-2_333.

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Pardasani, R. T., and P. Pardasani. "Molar magnetic moment of cobalt(II) complex with Schiff-base derived from 3-methylthiosemicarbazone and 5-formyl-6-hydroxycoumarin." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 2. Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62466-1_382.

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"Vitamin K Antagonist Hydroxycoumarins." In Dictionary of Toxicology. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-9283-6_2872.

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"3-Cyano-7-hydroxycoumarin (3-Cyanoumbelliferone)." In Handbook of Fluorescent Dyes and Probes. John Wiley & Sons, Inc, 2015. http://dx.doi.org/10.1002/9781119007104.ch54.

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"4-Heptadecyl-7-hydroxycoumarin (4-Heptadecylumbelliferone)." In Handbook of Fluorescent Dyes and Probes. John Wiley & Sons, Inc, 2015. http://dx.doi.org/10.1002/9781119007104.ch82.

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"7-Hydroxycoumarin-3-carboxylic acid succinimidyl ester." In Handbook of Fluorescent Dyes and Probes. John Wiley & Sons, Inc, 2015. http://dx.doi.org/10.1002/9781119007104.ch88.

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"Pacific Blue (6,8-Difluoro-7-hydroxycoumarin-3-carboxylic acid)." In Handbook of Fluorescent Dyes and Probes. John Wiley & Sons, Inc, 2015. http://dx.doi.org/10.1002/9781119007104.ch115.

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"7-Hydroxycoumarin-3-carboxylic acid (Umbelliferone-3-carboxylic acid)." In Handbook of Fluorescent Dyes and Probes. John Wiley & Sons, Inc, 2015. http://dx.doi.org/10.1002/9781119007104.ch87.

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Kaur, Jaskiran, Paras Famta, Navneet Khurana, Manish Vyas, and Gopal L. Khatik. "Biomedical applications of 4-hydroxycoumarin as a fungal metabolite and its derivatives." In New and Future Developments in Microbial Biotechnology and Bioengineering. Elsevier, 2020. http://dx.doi.org/10.1016/b978-0-12-821006-2.00016-9.

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MORIYA, Tetsuo, and Yoshihisa KAWAGUCHI. "AB INITIO MO CALCULATION OF THE STRUCTURE AND ENERGY LEVELS OF 7-HYDROXYCOUMARIN AND ITS TAUTOMER." In Computer Aided Innovation of New Materials. Elsevier, 1991. http://dx.doi.org/10.1016/b978-0-444-88864-8.50109-6.

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Conference papers on the topic "Hydroxycoumarins"

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Serra, Silvia, Andrea Chicca, Jürg Gertsch, Lourdes Santana, Eugenio Uriarte, and Giovanna Delogu. "Synthesis of a Series of Different Hydroxycoumarins and Their Cytotoxic Activity." In The 16th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2012. http://dx.doi.org/10.3390/ecsoc-16-01108.

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Chatterjee, Rana, Anindita Mukherjee, Grigory V. Zyryanov, and Adinath Majee. "Metal and solvent free direct C3-alkylation of 4-hydroxycoumarins with styrene." In PROCEEDINGS OF INTERNATIONAL CONFERENCE ON RECENT TRENDS IN MECHANICAL AND MATERIALS ENGINEERING: ICRTMME 2019. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0018529.

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Serra, Silvia, Eugenio Uriarte, Lourdes Santana, et al. "Synthesis of substituted 3-aryl-4-hydroxycoumarins of expected antimicrobial activity in tenacibaculosis disease." In The 15th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2011. http://dx.doi.org/10.3390/ecsoc-15-00653.

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Matos, Maria, Claudio Olea-azar, Fernanda Perez-Cruz, et al. "Insights into the antioxidant activity of phenolic compounds: Synthesis and electrochemical study of new series of hydroxycoumarins." In The 15th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2011. http://dx.doi.org/10.3390/ecsoc-15-00617.

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Dekamin, Mohammad G., Meysam Fallah, and Amene Yaghoubi. "Periodic mesoporous organosilica: as a novel and efficient nanocatalyst for the one-pot synthesis of 3,3'-arylmethylene-bis-4-hydroxycoumarins in water." In The 20th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2016. http://dx.doi.org/10.3390/ecsoc-20-a020.

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Kopylova, T. N., L. G. Samsonova, R. M. Gadirov, V. P. Khilya, V. V. Ishchenko, and O. V. Shablykina. "The nature of the photoprocesses in the new 7-hydroxycoumarines." In Atomic and Molecular Pulsed Lasers VII, edited by Victor F. Tarasenko. SPIE, 2007. http://dx.doi.org/10.1117/12.785624.

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Dimić, Dušan, Dejan Milenković, Edina Avdović, Goran Kaluđerović, and Jasmina Dimitrić Marković. "MOLECULAR DOCKING AND MOLECULAR DYNAMICS STUDIES OF THE INTERACTION BETWEEN COUMARIN-NEUROTRANSMITTER DERIVATIVES AND CARBONIC ANHYDRASE IX." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac,, 2021. http://dx.doi.org/10.46793/iccbi21.056d.

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Novel biologically active compounds can be obtained by the structural modification of coumarins. In this contribution, five new derivatives of 4-hydroxycoumarin with tyramine, octopamine, norepinephrine, 3-methoxytyramine, and dopamine were obtained. Their structures were optimized based on the previously obtained crystal structure of the 4-hydroxycoumarin-dopamine derivative. The special emphasis was put on the effect of various substituents on the structure of obtained compounds and intramolecular interactions governing the stability. To investigate their possible antitumor activity, molecul
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Dong, Sheying, Penghui Zhang, and Jing Li. "Microwave-Assisted Synthesis and Crystal Structure of 3',3-Benzylidene-Bis-4-Hydroxycoumarin." In 2009 Symposium on Photonics and Optoelectronics. IEEE eXpress Conference Publishing, 2009. http://dx.doi.org/10.1109/sopo.2009.5230279.

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Kurjan, Jakub, Rastislav Jendželovský, Zuzana Jendželovská, et al. "A novel silver complex with 4-hydroxycoumarin derivative: Synthesis, structure, and biological activity." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.447k.

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In this contribution, a novel coumarin-derivative ligand, and its silver(I) complex are reported. Ligand 3-(1-(2-pyridylamino)ethylidene)-2H-chromene-2,4-dione (HL) was prepared by reaction of 3-acetyl-4-hydroxycoumarin with 2-picolyl amine. Further, complex [Ag(HL)2]NO3 was prepared and both compounds were characterized by physico-chemical methods such as IR and NMR spectroscopy, elemental analysis, and structure of the ligand and the complex was confirmed by X-ray analysis. The stability of both compounds was measured by NMR spectroscopy. MTT assay and cell proliferation assay on human lung
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Avdović, Edina, Sandra Jovičić Milić, Dušica Simijonović, Danijela Stojković, Dejan Milenković, and Zoran Marković. "SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION AND BSA INTERACTIONS OF 3-(1-((4-HYDROXY PENTYLAMINO)ETHYLIDENE)CHROMAN-2,4-DIONE." In 17th International Conference on Fundamental and Applied Aspects of Physical Chemistry. Society of Physical Chemists of Serbia, 2024. https://doi.org/10.46793/phys.chem24i.053a.

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In this study, we synthesized a novel coumarin derivative, specifically 3-(1-((4-hydroxy pentylamino)ethylidene)cromane-2,4-dione by the reaction of 3-acetyl-4-hydroxycoumarin and 5- aminopentanol in methanol. The compound was obtained after 2 hours of reflux. The synthesized coumarin derivative was obtained in very good yield (80%) and characterized using elemental microanalysis, Uv-Vis, IR and NMR spectroscopy. Furthermore, the interaction of investigated compound with bovine serum albumin (BSA) was studied using fluorescence spectroscopy and the Stern-Volmer constant (Ksv), quenching rate c
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