Academic literature on the topic 'Hydroxylation reactions'

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Journal articles on the topic "Hydroxylation reactions"

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Holland, Herbert L., Frances M. Brown, P. Chinna Chenchaiah, and J. Appa Rao. "Hydroxylation of prostanoids by fungi. Synthesis of (−)-15-deoxy-19-(R)-hydroxy-PGE1 and (−)-15-deoxy-18-(S)-hydroxy-PGE1." Canadian Journal of Chemistry 68, no. 2 (1990): 282–93. http://dx.doi.org/10.1139/v90-039.

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A series of racemic substituted cyclopentanones, with alkyl groups corresponding to the upper prostanoid side chain and (or) the lower prostanoid side chain without the C-15 alcohol, has been synthesized. Using a steroid template for the prostanoid molecule as a basis for selection, fungi capable of hydroxylating steroids have been used to biotransform the prostanoid substrates. The predominant products were hydroxylated at the prostanoid C-18 and C-19 positions. The hydroxylations were enantioselective, with excesses in the range 10–60%, and in most cases the predominant configuration corresp
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Zimniak, P., E. J. Holsztynska, A. Radominska, M. Iscan, R. Lester та D. J. Waxman. "Distinct forms of cytochrome P-450 are responsible for 6β-hydroxylation of bile acids and of neutral steroids". Biochemical Journal 275, № 1 (1991): 105–11. http://dx.doi.org/10.1042/bj2750105.

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Cytochrome P-450-dependent 6 beta-hydroxylation of bile acids in rat liver contributes to the synthesis of the quantitatively important pool of 6-hydroxylated bile acids, as well as to the detoxification of hydrophobic bile acids. The lithocholic acid 6 beta-hydroxylation reaction was investigated and compared with androstenedione 6 beta-hydroxylation. Differential responses of these two activities to inducers and inhibitors of microsomal P-450 enzymes, lack of mutual inhibition by the two substrates and differential inhibition by antibodies raised against several purified hepatic cytochromes
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Holland, Herbert L., and Hedda K. Weber. "Enzymatic hydroxylation reactions." Current Opinion in Biotechnology 11, no. 6 (2000): 547–53. http://dx.doi.org/10.1016/s0958-1669(00)00142-7.

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Fan, Tengjiao, Guohui Sun, Lijiao Zhao, Xin Cui, and Rugang Zhong. "Metabolic Activation and Carcinogenesis of Tobacco-Specific Nitrosamine N’-Nitrosonornicotine (NNN): A Density Function Theory and Molecular Docking Study." International Journal of Environmental Research and Public Health 16, no. 2 (2019): 178. http://dx.doi.org/10.3390/ijerph16020178.

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N’-nitrosonornicotine (NNN) is one of the tobacco-specific nitrosamines (TSNAs) that exists widely in smoke and smokeless tobacco products. NNN can induce tumors in various laboratory animal models and has been identified by International Agency for Research on Cancer (IARC) as a human carcinogen. Metabolic activation of NNN is primarily initiated by cytochrome P450 enzymes (CYP450s) via 2′-hydroxylation or 5′-hydroxylation. Subsequently, the hydroxylating intermediates undergo spontaneous decomposition to generate diazohydroxides, which can be further converted to alkyldiazonium ions, followe
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Holland, Herbert L. "ChemInform Abstract: Stereoselective Hydroxylation Reactions." ChemInform 32, no. 21 (2010): no. http://dx.doi.org/10.1002/chin.200121255.

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Dardonville, Christophe, Henri Virelizier, Jean Boivin, and Christopher K. Jankowski. "Reactions of carboline." Spectroscopy 13, no. 4 (1997): 257–64. http://dx.doi.org/10.1155/1997/821241.

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The reactions of carboline under various oxidative conditions are reported. The soft aerobic radiolysis, hydroxylation and rearrangement transformations are studied using isotopic labelling and GC–MS techniques.
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Agarwal, Mahadev, Neelam Singla, and S. K. Singh. "To Synthesis and Characterization of Novel 1,3,4-Oxadiazinoindole Derivatives for the Purpose of Antidepressant Activity." INTERNATIONAL JOURNAL OF PHARMACEUTICAL QUALITY ASSURANCE 14, no. 03 (2023): 656–60. http://dx.doi.org/10.25258/ijpqa.14.3.33.

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The present paper is based on the combination of MAOI hydrazide moiety and tricyclic antidepressant moiety. This combination investigates new compounds as 1,3,4-oxadiazinoindole derivatives to find potent and safer antidepressants. Synthesis of 1,3,4-oxadiazinoindole derivatives are started from various animoacids. The sequence of synthesis reactions such as benzoylation reaction, Halo-De-hydroxylation (Nucleophilic substitution reaction), Schotten-Baumann reaction, Nucleophilic addition and finally cyclization reaction (Cyclo-De-Hydroxylation) are involved. Synthesized compounds are character
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Cryle, Max J., Jeanette E. Stok, and James J. De Voss. "Reactions Catalyzed by Bacterial Cytochromes P450." Australian Journal of Chemistry 56, no. 8 (2003): 749. http://dx.doi.org/10.1071/ch03040.

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The cytochromes P450 are a large family of oxidative haemoproteins that are responsible for a wide variety of oxidative transformations in a variety of organisms. This review focuses upon the reactions catalyzed specifically by bacterial enzymes, which includes aliphatic hydroxylation, alkene epoxidation, aromatic hydroxylation, oxidative phenolic coupling, heteroatom oxidation and dealkylation, and multiple oxidations including C–C bond cleavage. The potential for the practical application of the oxidizing power of these enzymes is briefly discussed.
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Paul, Melanie, Alexander Hoffmann, and Sonja Herres-Pawlis. "Room temperature stable multitalent: highly reactive and versatile copper guanidine complexes in oxygenation reactions." JBIC Journal of Biological Inorganic Chemistry 26, no. 2-3 (2021): 249–63. http://dx.doi.org/10.1007/s00775-021-01849-9.

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AbstractInspired by the efficiency of natural enzymes in organic transformation reactions, the development of synthetic catalysts for oxygenation and oxidation reactions under mild conditions still remains challenging. Tyrosinases serve as archetype when it comes to hydroxylation reactions involving molecular oxygen. We herein present new copper(I) guanidine halide complexes, capable of the activation of molecular oxygen at room temperature. The formation of the reactive bis(µ-oxido) dicopper(III) species and the influence of the anion are investigated by UV/Vis spectroscopy, mass spectrometry
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Lee, Gun Dae, Sung Gab Kim, Hee Hoon Jeong, Seong Soo Park, and Seong Soo Hong. "Photocatalytic Hydroxylation of Phenol over Ti-Containing Zeolites (TS-1, Ti-MCM-41)." Solid State Phenomena 124-126 (June 2007): 1793–96. http://dx.doi.org/10.4028/www.scientific.net/ssp.124-126.1793.

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The photo-catalytic hydroxylation of phenol with hydrogen peroxide was carried out over TS-1 and Ti-MCM-41 catalysts. For comparison, the dark (thermal)-catalytic hydroxylation of phenol was also performed. The difference in catalytic behaviors of TS-1 and Ti-MCM-41 and product distribution in both the reactions were investigated. The TS-1 and Ti-MCM-41 catalysts having the Si/Ti ratio of 50 were prepared by in-situ crystallization and characterized using XRD, UV-DRS. In the all reactions, the main products were catechol (CAT), hydroquinone (HQ) and benzoquinone (BQ). In dark (thermal)-reactio
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Dissertations / Theses on the topic "Hydroxylation reactions"

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Bhowmick, Rupa. "Transition metal-ion mediated hydroxylation reactions." Thesis, University of North Bengal, 1993. http://hdl.handle.net/123456789/867.

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Joseph, Jan Felix [Verfasser]. "Metabolism of androstane derivatives with focus on hydroxylation reactions / Jan Felix Joseph." Berlin : Freie Universität Berlin, 2016. http://d-nb.info/1122438877/34.

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Boldovjaková, Tatiana. "Post-polymerační modifikace polyolefinů pro přípravu hydroxylovaných makroiniciátorů." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2020. http://www.nusl.cz/ntk/nusl-432943.

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The diploma thesis deals with post-polymerization hydroxylation of polypropylene in solid state. Regarding the literature review, polypropylene was hydroxylated by radical grafting in aqueous solution of potassium persulfate at 100 °C, under nitrogen atmosphere for 60 minutes. Hydroxylation of polypropylene was performed at different concentrations of potassium persulfate (1; 5; 10 mol. %) and two different water/potassium persulfate molar ratios. The effects of reaction system composition and reaction conditions on reaction efficiency, extent of side reactions, thermal and rheological propert
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Bahrami, Atieh. "Immobilization of cytochrome P450 BM3 from Bacillus megaterium on magnetic nanoparticles to develop an effective biocatalyst for hydroxylation reactions." Doctoral thesis, Université Laval, 2018. http://hdl.handle.net/20.500.11794/34494.

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Les catalyseurs chimiques sont utilisés dans différents procédés de synthèse. Cependant, la pollution qu'ils causent sur l'environnement n’est pas prise en considération. Les procédés de synthèse chimique nécessitent généralement un grand volume de solvants organiques, produisant d’énormes quantités de déchets chimiques, souvent toxiques et non dégradables. Le remplacement des catalyseurs chimiques par des biocatalyseurs (enzymes) pourrait donc bénéficier de leur nature écologique et de leur grande sélectivité envers les produits désirés. Néanmoins, la faible activité et stabilité des enzymes
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Bredendiek, Felix [Verfasser]. "Orthogonal Analytical Approaches for the Investigation of Specific Metabolic Pathways of 17α-Methyltestosterone with the Focus on Hydroxylation Reactions / Felix Bredendiek". Berlin : Freie Universität Berlin, 2021. http://d-nb.info/1233986848/34.

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Burg, Finn [Verfasser], Thorsten [Akademischer Betreuer] Bach, Mathias [Gutachter] Senge, Thorsten [Gutachter] Bach, and Wolfgang [Gutachter] Eisenreich. "Bioinspired Site- and Enantioselective Hydroxylation Reactions Enabled by Molecular Recognition / Finn Burg ; Gutachter: Mathias Senge, Thorsten Bach, Wolfgang Eisenreich ; Betreuer: Thorsten Bach." München : Universitätsbibliothek der TU München, 2020. http://d-nb.info/1215837895/34.

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Förster, Anja. "Ab-initio studies of reactions to functionalize carbon nanotubes." Bachelor's thesis, Universitätsbibliothek Chemnitz, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-qucosa-103907.

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Since the rediscovery of carbon nanotubes (CNTs) due to the publication of Sumio Iijima's article Helical microtubules of graphitic carbon in the magazine Nature in 1991 the interest in carbon nanotubes has rapidly increased. This bachelor thesis also deals with this popular material with the aim to functionalize CNTs for further uses in the microelectronic industry. A promising approach is the functionalization of the CNTs with metal nanoparticles or metal films. To achieve this, one can perform an atomic layer deposition (ALD) on CNTs. In the present work the Trimethylaluminum (TMA) ALD i
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Gupta, Puneet [Verfasser], Max C. [Akademischer Betreuer] [Gutachter] Holthausen, and Siegfried [Gutachter] Schindler. "Hydroxylation reactions in bioinorganic models for copper enzymes : a density functional theory assessment / Puneet Gupta. Betreuer: Max C. Holthausen. Gutachter: Max C. Holthausen ; Siegfried Schindler." Frankfurt am Main : Universitätsbibliothek Johann Christian Senckenberg, 2016. http://d-nb.info/1103571826/34.

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Wu, Ju. "Electrochemical and Non-electrochemical Oxidative Dearomatization Reactions of Indoles." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLS368.

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L'électrochimie est apparue comme un puissant outil de synthèse durable en chimie organique, qui évite l'utilisation d'un oxydant stoechiométrique externe et permet le développement de méthodes de difonctionnalisation très efficaces et sélectives des indoles dans des conditions douces. L'utilisation de médiateurs redox pour réaliser l'électrolyse indirecte a gagné en importance ces dernières année, ce qui offre de nombreux avantages par rapport à l'électrolyse directe. Les réactions de désaromatisation des hétéroarènes achiraux, et en particulier des indoles, donnent des structures tridimensio
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Hillen, Michael [Verfasser]. "Stabilization of physiology and C-H hydroxylation rates of whole-cell biocatalysts by reaction engineering / Michael Hillen." Aachen : Shaker, 2019. http://d-nb.info/1188552678/34.

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Books on the topic "Hydroxylation reactions"

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Shaik, Sason, Samuel P. de Visser, Devesh Kumar, Andrew W. Munro, and Saptaswa Sen. Iron-Containing Enzymes: Versatile Catalysts of Hydroxylation Reactions in Nature. Royal Society of Chemistry, The, 2011.

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Neese, Frank, Samuel P. de Visser, Devesh Kumar, Chris Mowat, and Adrian Mulholland. Iron-Containing Enzymes: Versatile Catalysts of Hydroxylation Reactions in Nature. Royal Society of Chemistry, The, 2011.

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Book chapters on the topic "Hydroxylation reactions"

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Li, Jie Jack. "Sharpless asymmetric amino hydroxylation." In Name Reactions. Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-662-05336-2_271.

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Li, Jie Jack. "Sharpless asymmetric amino-hydroxylation." In Name Reactions. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-03979-4_248.

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Jack Li, Jie. "Sharpless asymmetric amino-hydroxylation." In Name Reactions. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-01053-8_232.

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Li, Jie Jack. "Sharpless Asymmetric Amino-hydroxylation." In Name Reactions. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-50865-4_136.

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Hayashi, Yujiro, Mitsuru Shoji, Rosaria Ciriminna, et al. "Hydroxylation, Epoxidation and Related Reactions." In Regio- and Stereo- Controlled Oxidations and Reductions. John Wiley & Sons, Ltd, 2007. http://dx.doi.org/10.1002/9780470090244.ch6.

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Wang, Xiaoshi. "Efficient and Selective Alkane Hydroxylation Reactions Catalyzed by the Fungal Peroxygenase AaeAPO." In A Novel Heme-Thiolate Peroxygenase AaeAPO and Its Implications for C-H Activation Chemistry. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-03236-8_2.

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Suhendra, Dedy, Erin Ryantin Gunawan, Sri Seno Handayani, and Haerani. "Synthesis of Polyol Through Epoxidation and Hydroxylation Reactions of Ricinus Communis L. Oil." In Proceedings of the 2nd International Conference on Science Education and Sciences 2022 (ICSES 2022). Atlantis Press International BV, 2023. http://dx.doi.org/10.2991/978-94-6463-232-3_30.

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Annese, Cosimo, Lucia D’Accolti, Caterina Fusco, and Fulvio Ciriaco. "Ab-initio Investigation of Unexpected Aspects of Hydroxylation of Diketopiperazines by Reaction with Dioxiranes." In Communications in Computer and Information Science. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-32695-5_13.

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Groves, John T., and Zeev Gross. "On the Mechanism of Epoxidation and Hydroxylation Catalyzed by Iron Porphyrins. Evidence for Non-Intersecting Reaction Pathways." In Bioinorganic Chemistry. Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-011-0255-1_4.

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Osborne, Robert L., and Judith P. Klinman. "Insights into the Proposed Copper-Oxygen Intermediates that Regulate the Mechanism of Reactions Catalyzed by Dopamine β-Monooxygenase, Peptidylglycine α-Hydroxylating Monooxygenase, and Tyramine β-Monooxygenase." In Copper-Oxygen Chemistry. John Wiley & Sons, Inc., 2011. http://dx.doi.org/10.1002/9781118094365.ch1.

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Conference papers on the topic "Hydroxylation reactions"

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Mocanu, Larisa, Maria Gonta, and Gheorghe Duca. "Study of kinetics of transformation of galliric acid using possible oxidation processes in model systems." In Conferința științifică națională cu participare internațională "Integrare prin cercetare și inovare", dedicată Zilei Internaționale a Științei pentru Pace și Dezvoltare. Moldova State University, 2025. https://doi.org/10.59295/spd2024n.88.

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Gallic acid is a naturally occurring phenolic compound. Due to its persistence and potential toxicity, presents environmental challenges. Removal of gallic acid from wastewater, allows recycling and reuse of water in various industrial processes, reducing water consumption and contributing to sustainable practices. As a result, the removal of gallic acid from aqueous model solutions was studied by applying (AOPs): AG/Fenton, AG/Fenton/UV, AG/TiO2/H2O2/UV according to different physicochemical parameters. AOPs have emerged as promising techniques due to their ability to generate highly reactive
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Boettger, Jason D., and James D. Kubicki. "ISOTOPIC FRACTIONATION AND CLUMPING IN THE CO2 HYDRATION AND HYDROXYLATION REACTIONS: EVALUATING THE INFLUENCE OF HYDROGEN-BONDING VIA QUANTUM MECHANICAL CALCULATIONS." In GSA Annual Meeting in Indianapolis, Indiana, USA - 2018. Geological Society of America, 2018. http://dx.doi.org/10.1130/abs/2018am-319274.

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Peterle, Marcos M., Marcelo V. Marques та Marcus M. Sá. "α-Hydroxylation of malonates under mild reaction conditions". У 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_2013820152632.

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