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Journal articles on the topic 'Hydroxypheny'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Amel S. Mahdi, Bayader F. Abbas, and Mudeer M. Merza. "Photo degradation of Lanthanum (III) Complex with 1, 2 , 4-Thiadiazole in Dimethyl Sulsoxide ( DMSO ) Solvent." journal of the college of basic education 21, no. 87 (2022): 169–82. http://dx.doi.org/10.35950/cbej.v21i87.8863.

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5- Amino -3- [4- O- hydroxypheny Ithiosemi carbazido ] -1,2,4-thiadiazole compound has been prepared by the reaction of ( 3-mercapto -5- ami,2,4- thiadiazole) with ( O-hydroxyphenyl thiosemicarbazide) in mole ratios of (1:1) .The ligand has been characterized and its structure was elucidated depending upon the spectral data of IR and U.V-Vis spectra . Lanthanum complex of the formula [La( C9H10N6S2O)2Cl2]Cl was prepared through the reaction of the prepared ligand with lanthanum chloride in mole ratios (2:1) respectively . The mode of bonding and overall geometry of the complex was determined t

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2

BIPIN, B. MAHAPATRA, K. BHOI PRAMOD, K. KAR SUKHENDU, and PRASAD SITARAM. "Polymetallic Complexes. Part-XXXIX. Complexes of Cobalt-, Nickel-, Copper-, Zinc-, Cadmium- and Mercury(II) with Chelating Azo Dye Ligands, 1-(2'-Hydroxypheny 1-1 ')azo-1-cyanoethyl Acetate and 1-(2' -Carboxyphenyl-1')azo-1-cyanoethyl Acetate." Journal of Indian Chemical Society Vol. 72, Jun 1995 (1995): 399–401. https://doi.org/10.5281/zenodo.5904977.

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Post-Graduate Department of Chemistry, G. M. College, Sambalpur-768 004 <em>Manuscript received 27 Apnl 1992, revised 22 November 1993. accepted 29 December 1993</em> Polymetallic Complexes. Part-XXXIX. Complexes of Cobalt-, Nickel-, Copper-, Zinc-, Cadmium- and Mercury(II) with Chelating Azo Dye Ligands, 1-(2'-Hydroxypheny 1-1 ')azo-1-cyanoethyl Acetate and 1-(2' -Carboxyphenyl-1')azo-1-cyanoethyl Acetate

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3

Hong-Wen, Gao, Yang Jia-Xiang, and Ye Qing-Song. "Property of cadmium and zinc complex with meso-tetra(3,5-dibromo-4-hydroxy-phenyl)porphyrin and simultaneous determination of cadmium and zinc by spectral correction method." Journal of Indian Chemical Society Vol. 78, May 2001 (2001): 246–49. https://doi.org/10.5281/zenodo.5873188.

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School of Chemistry and Chemical Engineering, Anhui University, Hefei 230039, P.R. China <em>E-mail</em> : gaohongw@mail.hf.ah.cn <em>Manuscript received 24 April 2000, revised 17 July 2000. accepted 16 December 2000</em> The reactions between cadmium(II) and <em>meso</em>-tetra(3,5-dibromo-4-hydroxyphenyl)porphyrin (TDBHPP) and zinc(ll) and TDBHPP are both highly sensitive at <em>p</em>H 10. The <em>β</em>-correction technique has been applied in the simultaneous determination of Cd and Zn instead of the classical spectrophotometry. Two synthetic samples have been determined satisfactori

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4

Hammam, A. "Solvatochromic studies on 2-[(2-hydroxypheny)azo]-4-5-diphenylimidazole." Dyes and Pigments 35, no. 3 (1997): 289–96. http://dx.doi.org/10.1016/s0143-7208(96)00107-6.

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5

Yamada, Arisa, Shigeki Hattori, Satoshi Saito, Koji Asakawa, Ikuo Yoneda, and Tetsuro Nakasugi. "Development of High Resolution Molecular Resist Based on Tris((hydroxypheny)pheny)benzene." Journal of Photopolymer Science and Technology 23, no. 1 (2010): 91–95. http://dx.doi.org/10.2494/photopolymer.23.91.

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6

Tatehata, Hideki, Tetsuya Fukuoka, and Akira Mochizuki. "Synthesis and characterization of poly(hydroxyether). II. Poly(hydroxyethers) based on various bisphenols and 2,2-bis(4-hydroxypheny)hexafluoropropane." Journal of Applied Polymer Science 80, no. 10 (2001): 1697–709. http://dx.doi.org/10.1002/app.1265.

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7

Li, Chaozheng, Bo Hu, Yonghua Cao, and Yongfeng Li. "Elaborating the excited-state double proton transfer mechanism and multiple fluorescent characteristics of 3,5-bis(2-hydroxypheny)-1H-1,2,4-triazole." Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 258 (September 2021): 119854. http://dx.doi.org/10.1016/j.saa.2021.119854.

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8

Watson, KG, and A. Serban. "Evaluation of the Elbs Persulfate Oxidation Reaction for the Preparation of Aryloxyphenoxypropionate Herbicides." Australian Journal of Chemistry 48, no. 8 (1995): 1503. http://dx.doi.org/10.1071/ch9951503.

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A new, simple method for the preparation of several 4-( aryloxy )phenols (2a-d) and alkyl 2-(4-hydroxyphenoxy)propionates (3a,b) is described. These compounds are key precursors for the synthesis of important aryloxyphenoxypropionate herbicides (1a-d). The method uses the Elbs persulfate oxidation to convert phenol into 4-hydroxyphenyl sulfate (5). The free hydroxy group is then reacted with various aryl halides and alkyl 2-halopropionates. Mild hydrolysis of the sulfate group with boiling acetic acid then gives the products (2a-d) and (3a,b), generally in modest to good yield.

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9

Yokozeki, Kenzo, Shigeru Nakamori, Chikahiko Eguchi, Kazuhiko Yamada, and Koji Mitsugi. "Screening of Microorganisms Producingd-p-Hydroxyphenyl-glycine from Dl-5-(-Hydroxyphenyty)hydantoin." Agricultural and Biological Chemistry 51, no. 2 (1987): 355–62. http://dx.doi.org/10.1080/00021369.1987.10868067.

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10

Zeba, N. Siddiqui, and Zaman Asif. "Pyrazoles from 3-formylchromone-ethyl vinyl ether adduct." Journal of Indian Chemical Society Vol. 76, Jul 1999 (1999): 368–69. https://doi.org/10.5281/zenodo.5848892.

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Department of Chemistry, Aligarh Muslim University, Aligarh-202 002, India <em>Manuscript received 2 March 1998, revised 28 December 1998, accepted 9 March 1999</em> Reaction of (E)-ß-(4-oxo-4<em>H</em>-1-benzopyran-3-yl)acrolein (2) with phenylhydrazine yields (E)-ß-(4-oxo-4/1-1-benzopyran-3- yl)acrolein phenylhydrazone (4) and [1-phenyl-5-(2-hydroxyphenyppyrazol-4-yl]acrolein phenylhydrazone (5). 3-RE,E)-5- Oxohexa-1,3-dien-1-y1]-1-benzopyran-4-one-5-phenylhydrazone (6) and phenylhydrazone (7) of 6-[5-(2-hydroxypheny1)-1- phenylpyrazol-4-yl]hexa-3,4,5,6-dien-2-one have been synth

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11

Wang, Shenshuai, Yingjie Huang, Weiye Sun, and Xufeng Lin. "Synthesis, Characterization, and Evaluation of a Hindered Phenol-Linked Benzophenone Hybrid Compound as a Potential Polymer Anti-Aging Agent." Antioxidants 13, no. 8 (2024): 894. http://dx.doi.org/10.3390/antiox13080894.

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Hindered phenol antioxidants and benzophenone UV absorbers are common polymer additives and often used in combination applications to enhance the anti-aging performance of polymer materials. This study primarily aims to incorporate hindered phenol and benzophenone structures into a single molecule to develop a multifunctional polymer additive with good anti-aging performance. Thus, a novel potential polymer anti-aging agent, namely 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionic acid 3-(4-benzoyl-3-hydroxyphenoxy)propyl ester (3C), was synthesized using 3-(3,5-di-tert-butyl-4-hydroxyphenyl)prop

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12

Nisha, Singh, K. Sangwan Naresh, and S. Dhindsa Kuldip. "Complexes of derivatives of 4,5-dihydro-1H-pyrazole as potential pesticides." Journal of Indian Chemical Society Vol. 78, Mar 2001 (2001): 119–22. https://doi.org/10.5281/zenodo.5849432.

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Department of Chemistry, CCS Haryana Agricultural University, Hisar-125 004, India <em>Manuscript received 22 March 2000, revised 4 September 2000, accepted 30 November 2000</em> Cyclization of 3-aryl-1-(2-hydroxyphenyl)prop-2-en-1-ones with hydrazine hydrate in refluxing acetic acid furnishes 1-acetyl-5-aryl-4,5-dihydro-3-(2-hydroxypheny1)-1<em>H</em>-pyrazoles HL<sup>1</sup>-HL<sup>4</sup>, Ar = Ph, 4-CH<sub>3</sub>O-C<sub>6</sub>H<sub>4</sub>_, 2-furyl, 2-thienyl, respectively). Refluxing of ligands HL<sup>1</sup>-HL<sup>4</sup> with Mn<sup>II</sup>, Co<sup>II</sup>, Ni<sup>II</sup>, C

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13

B., ANANDAM, and LINGAIAH P. "A Study on Metal Chelates of Substituted Hydroxyphenylpyrazoles with some Bivalent Transition Metal Ions." Journal of Indian Chemical Society Vol. 70, Jan 1993 (1993): 8–10. https://doi.org/10.5281/zenodo.5902578.

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Department of Chemistry, C. K. M. Arts and Science College, Warangal-506 009 Department of Chemistry, Kakaliya University, Warangal-506 009 <em>Manuscript received 2 September 1991, revised 1 September 1992, accepted 17 September 1992</em> The stability constants of metal chelate & of substituted hydroxyphenylpyrazoles, viz. 3(5)-(2· hydroxyphenyl)· -(3)-phenylpyrazole (OHPPPz), 3(5)<em>·</em>(2·hydroxyphenl)-5(3)-(4·chlororphenl) pyrazole (OHPCPPz) and 3·(2-bydroxyphenyl)-1 ,5-diphenylpyrazole (OHPDPPz) with Co<sup>II</sup> Ni<sup>II</sup>. C

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14

Taiwo, Olayombo Margaret, Olaoluwa Omosalewa Olaoluwa, Olapeju Oluyemisi Aiyelaagbe, and Josphat Clement Matasyoh. "Phytochemical Constituents of F. Sagittifolia Warburg ex Mildbraed & Burret Leaves with Antimicrobial Activity." Biology, Medicine, & Natural Product Chemistry 11, no. 1 (2022): 75–81. http://dx.doi.org/10.14421/biomedich.2022.111.75-81.

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The leaves and bark of Ficus sagittifolia have been used as a cure for stomach and pulmonary disorders, respectively. The bark is edible and is taken against colic. From the leaves of F. sagittifolia, a steroidal glycoside named Stigmast-5,22-diene-3-O-β-D-glucopyranoside 1 and three isoflavonoids named 5-hydroxy-3-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one 2, 5-hydroxy-3(4-hydroxylphenyl)-8,8-dimethylpyrano[2,3-f]-chromen-4(8H)-one 3 and 5-hydroxy-3-(4-hydroxyphemyl)-8,8-dimethylpyrano[3,2-g}-chromen-4(8H)-one 4 were isolated, and this is the first report of the isolation of these compounds

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15

Nsira, Asma, Ahlem Karoui, Rafik Gharbi, and Moncef Msaddek. "Chemoselectivity of the 1,3-Dipolar Cycloaddition of Some Diazoalkanes with 1,5-Benzodiazepine Derivatives." Journal of Chemical Research 36, no. 3 (2012): 152–56. http://dx.doi.org/10.3184/174751912x13300109535030.

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Benzodiazepines are pharmaceutically important synthetic materials. Reaction of the 4-(2-hydroxyphenyl)-1,5-benzodiazepin-2-one with 2-diazopropane (DAP) gave a mixture of the 2-isopropylether of 4-(2-hydroxyphenyl)-3H-1,5-benzodiazepine and 1-isopropyl-4-(2-hydroxyphenyl)-3H-1,5-benzodiazepin-2-one. Whilst diphenyldiazomethane (DPDM) gave 1-benzhydryl-4-(2-hydroxyphenyl)-3H-1,5-benzodiazepin-2-one. Reaction of the corresponding thione with DAP led to the 2-isopropylthioether of 4-(2-hydroxyphenyl)-3H-1,5-benzodiazepine and 1-isopropyl-4-(2-hydroxyphenyl)-1,5-benzodiazepine-2-thione while the

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16

XIAO, DONG, GUILAN ZHANG, HAIYAN WANG, GUOQING TANG, and WENJU CHEN. "INVESTIGATION ON NONLINEAR TRANSMISSION PROPERTY OF EXCITED STATE PROTON TRANSFER MOLECULE 2-(2′-HYDROXYPHENYL)BENZOXAZOLE." Journal of Nonlinear Optical Physics & Materials 09, no. 03 (2000): 309–14. http://dx.doi.org/10.1142/s0218863500000248.

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Nonlinear transmission property of excited state proton transfer molecule 2-(2′-hydroxyphenyl)benzoxazole was investigated at 355 nm and 532 nm using picosecond laser pulses. The experiment result shows that the transmissivity of 2-(2′-hydroxyphenyl)benzoxazole is nonlinear at 355 nm but it is linear at 532 nm. The nonlinear transmissivity of 2-(2′-hydroxyphenyl)benzoxazole originates from the larger nonlinearity of tautomer formed in excited state proton transfer process. Therefore 2-(2′-hydroxyphenyl)benzoxazole might be used as ultrafast optical amplitude limit material.

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17

Tesakova, M. V., and V. I. Parfenyuk. "Influence of the nature of monomer on electropolymerization processes and physical and chemical properties of films based on hydroxy-substituted tetraphenylporphyrins." Perspektivnye Materialy 3 (2021): 30–41. http://dx.doi.org/10.30791/1028-978x-2021-3-30-41.

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The ability to oxidatively polymerization from a solution in ethanol of tetraphenylporphyrin derivatives: 5,10,15,20-tetrakis(4-hydroxyphenyl)porphyrin, 5,10,15,20-tetrakis(3-hydroxyphenyl)porphyrin, Zn-5,10,15,20-tetrakis(4-hydroxyphenyl)porphyrin, Zn-5,10,15,20-tetrakis(3-hydroxyphenyl)porphyrin were studied. The polymerization of 5,10,15,20-tetrakis(3-hydroxyphenyl)porphyrin does not occur; three of the four studied porphyrins form thin transparent polyporphyrin films tightly adhered to the electrodes surface. The influence of the nature of the monomer, the deposition mode, and the supporti

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18

Bonnett, R., R. D. White, U. J. Winfield, and M. C. Berenbaum. "Hydroporphyrins of the meso-tetra(hydroxyphenyl)porphyrin series as tumour photosensitizers." Biochemical Journal 261, no. 1 (1989): 277–80. http://dx.doi.org/10.1042/bj2610277.

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Four new hydroporphyrins [the o, m and p isomers of 5,10,15,20-tetra(hydroxyphenyl)chlorin and 5,10,15,20-tetra(m-hydroxyphenyl)bacteriochlorin] related to the tetra(hydroxyphenyl)porphyrins have been prepared. They show the expected strong absorption bands in the red region of the visible spectrum and are found to be very effective tumour photosensitizers.

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19

Kaewmati, Patcharin, Yumi Yakiyama, Hiroyoshi Ohtsu, et al. "Tris(2-hydroxyphenyl)triazasumanene: bowl-shaped excited-state intramolecular proton transfer (ESIPT) fluorophore coupled with aggregation-induced enhanced emission (AIEE)." Materials Chemistry Frontiers 2, no. 3 (2018): 514–19. http://dx.doi.org/10.1039/c7qm00530j.

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20

Gharbi, Rafik, Mouna Ben-Youssef, Marie-Thérèse Martin, and Zine Mighri. "Reactivity Studies on a Novel 4-(2-hydroxyphenyl)-1,3-dihydro-1,5-benzodiazepine-2-thione." Journal of Chemical Research 2005, no. 4 (2005): 257–61. http://dx.doi.org/10.3184/0308234054213410.

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The novel 4-(2-hydroxyphenyl)-1,3-dihydro-1,5-benzodiazepine-2-thione (4) has been synthesised and used as precursor to the hitherto unreported 7-methylthio[1]benzopyrano[4,3-c][1,5]-benzodiazepine (7). Hydrazinolysis of 4 gave 5-(2-aminophenylamino)-3-(2-hydroxyphenyl)-1H-pyrazole (9) which with excess of N,N-dimethylformamide dimethylacetal formed the 5-(2-hydroxyphenyl-2H-pyrazol-3-yl)-1H-benzimidazole (10).

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21

Journal, Baghdad Science. "Synthesis and Characterization of Five, Sevene Heterocyclic Membered Rings." Baghdad Science Journal 10, no. 3 (2013): 803–17. http://dx.doi.org/10.21123/bsj.10.3.803-817.

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New compounds containing heterocyclic units have been synthesized. These compounds include 2-amino 5- phenyl-1,3,4-thiadiazole (1) as starting material to prepare the Schiff bases 2N[3-nitrobenzylidene -2 hydroxy benzylidene and 4-N,N-dimethyl aminobenzylidene] -5-phenyl-1,3,4-thiadiazole (2abc) , 2N[3-nitrophenyl, 2-hydroxyphenyl or 4-N,N-dimethylaminophenyl] 3-]2-amino-5-phenyl-1,3,4-thiadiazole]-2,3-dihydro-[1,3]oxazepine-benzo-4,7-dione] (3abc), 2N[3-nitrophenyl,2-hydroxyphenyl,4-N,N-dimethylaminophenyl]-3-[2-amino-5-phenyl-1,3,4-thiadiazole-2-yl]-2,3-dihydro-[1,3]oxazepine-4,7-dione[(4abc

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22

Mahmoud, Muhaned J., Ibtisam K. Jassim, and Muhanned A. Mahmoud. "Synthesis and Characterization of Five, Sevene Heterocyclic Membered Rings." Baghdad Science Journal 10, no. 3 (2013): 803–17. http://dx.doi.org/10.21123/bsj.2013.10.3.803-817.

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New compounds containing heterocyclic units have been synthesized. These compounds include 2-amino 5- phenyl-1,3,4-thiadiazole (1) as starting material to prepare the Schiff bases 2N[3-nitrobenzylidene -2 hydroxy benzylidene and 4-N,N-dimethyl aminobenzylidene] -5-phenyl-1,3,4-thiadiazole (2abc) , 2N[3-nitrophenyl, 2-hydroxyphenyl or 4-N,N-dimethylaminophenyl] 3-]2-amino-5-phenyl-1,3,4-thiadiazole]-2,3-dihydro-[1,3]oxazepine-benzo-4,7-dione] (3abc), 2N[3-nitrophenyl,2-hydroxyphenyl,4-N,N-dimethylaminophenyl]-3-[2-amino-5-phenyl-1,3,4-thiadiazole-2-yl]-2,3-dihydro-[1,3]oxazepine-4,7-dione[(4abc

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23

Krishnamurthy, Naik, and Narashimaiah Shashikala. "Synthesis of ruthenium(II) carbonyl complexes with 2-monosubstituted and 1,2-disubstituted benzimidazoles." Journal of the Serbian Chemical Society 74, no. 10 (2009): 1085–96. http://dx.doi.org/10.2298/jsc0910085k.

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The reaction of the polymeric carbonyl complex [RuCl2(CO)2]x with 2-monosubstituted and 1,2-disubstituted benzimidazoles and 1,4-bis(benzimidazol- 2-yl)benzene (L9) in 2-methoxyethanol produces various coloured complexes of the formulae [Ru(CO)2Cl2(L)2]?xH2O (L = 1-(o-hydroxybenzyl)-2-(o-hydroxyphenyl)benzimidazole (L1), 1-(o-hydroxyphenyl)benzimidazole (L4), 1-(p-hydroxyphenyl)benzimidazole (L5), 1-(p-chlorobenzyl)-2-p-chlorophenyl) benzimidazole (L7), 1-[1-(dimethylamino)benzyl]-2-[1-(dimethylamino) phenyl]benzimidazole (L10), x = 0; L = 2-benzylbenzimidazole (L8), 1,4-bis(benzimidazol-2-yl)

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24

Y., D. KULKARNI, and BISHNOI ABHA. "Synthesis and Biological Activity of 2-Phthalimidomethyl- 3-(3-substituted-aminomethyl- 4-hydroxyphenyl )-6-substituted/6,8-disubstituted- 4( 3H)-oxo-3,1-quinazolines." Journal of Indian Chemical Society Vol. 67, Oct. 1990 (1990): 852–54. https://doi.org/10.5281/zenodo.6257668.

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Department of Chemistry, Lucknow  University, Lucknow-226  007 Pharmacology Division. Central Drug Research Institute, Lucknow-226 007 <em>Manuscript received 28 November 1989, revised 12 April 1990, accepted 3 July 1990</em> Synthesis and Biological Activity of  2-Phthalimidomethyl-3-(3-substituted-aminomethyl- 4-hydroxyphenyl)-6-substituted/6,8- disubstituted- 4(3<em>H</em>)-oxo-3,1-quinazolines  

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25

(Miss), P. W. CHINCHKHEDE, and N. INGLE V. "Synthesis of 3-Arylidine-2-(o-hydroxyphenyl)- 4-aryl-1,5-benzodiazepines." Journal of Indian Chemical Society Vol. 67, Oct. 1990 (1990): 855–56. https://doi.org/10.5281/zenodo.6278523.

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Department of Chemistry, Nagpur University, Nagpur-440 010 <em>Manuscript received 17 April 1990, accepted 26 July 1990</em> Synthesis of 3-Arylidine-2-(<em>o</em>-hydroxyphenyl)- 4-aryl-1,5-benzodiazepines

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26

Golden, Adam H., and Maitland Jones. "(Hydroxyphenyl)carbenes1,2." Journal of Organic Chemistry 61, no. 13 (1996): 4460–61. http://dx.doi.org/10.1021/jo952003d.

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27

Seidel, Rüdiger W., Richard Goddard, and Iris M. Oppel. "Isomorphous free-base, Ni(ii)- and Cu(ii)-5,10,15,20-tetra(4-hydroxyphenyl)porphyrin nitrobenzene hexasolvates with tetragonal 3D hydrogen-bonded network structures." CrystEngComm 16, no. 45 (2014): 10505–11. http://dx.doi.org/10.1039/c4ce01881h.

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The crystal structures of 5,10,15,20-tetra(4-hydroxyphenyl)-21,23H-porphyrin nitrobenzene hexasolvate (1), 5,10,15,20-tetra(4-hydroxyphenyl)porphyrinatonickel(ii) and -copper(ii)nitrobenzene hexasolvates (2and3) are described.

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28

Kirejev, V., A. R. Gonçalves, C. Aggelidou та ін. "Photophysics and ex vivo biodistribution of β-cyclodextrin-meso-tetra(m-hydroxyphenyl)porphyrin conjugate for biomedical applications". Photochem. Photobiol. Sci. 13, № 8 (2014): 1185–91. http://dx.doi.org/10.1039/c4pp00088a.

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Photophysics andex vivobiodistribution of porphyrin (meso-tetra(m-hydroxyphenyl)porphyrin;mTHPP) and porphyrin-cyclodextrin conjugate (β-cyclodextrin-meso-tetra(m-hydroxyphenyl)porphyrin; CD-mTHPP) were investigated and compared.

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29

Evens, Kaarin K., and Kathryn E. Splan. "Spectroscopic characterization of free-base hydroxy(arylethynyl)porphyrins in acidic and basic media." Journal of Porphyrins and Phthalocyanines 21, no. 10 (2017): 680–91. http://dx.doi.org/10.1142/s1088424617500675.

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The addition of arylethynyl groups to the porphyrin macrocycle represents an effective strategy with which to enhance the light-harvesting properties of porphyrins. We now extend this modification to arylethynyl porphyrins with two or four [Formula: see text]-hydroxyphenyl substituents. Arylethynyl porphyrins bearing four, but not two, [Formula: see text]-hydroxyphenyl substituents show evidence of aggregation under acidic conditions. Under basic conditions, deprotonation of the peripheral hydroxyphenyl substituents results in substantially red-shifted spectral features and enhanced absorption

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30

Tumosienė, Ingrida, Kristina Kantminienė, Ilona Jonuškienė, Artūras Peleckis, Sergey Belyakov, and Vytautas Mickevičius. "Synthesis of 1-(5-Chloro-2-hydroxyphenyl)-5-oxopyrrolidine-3-carboxylic Acid Derivatives and Their Antioxidant Activity." Molecules 24, no. 5 (2019): 971. http://dx.doi.org/10.3390/molecules24050971.

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A series of novel 1-(5-chloro-2-hydroxyphenyl)-5-oxopyrrolidine-3-carboxylic acid derivatives containing chloro, hydroxyl, isopropyl, nitro, nitroso, and amino substituents at benzene ring and 1-(5-chloro-2-hydroxyphenyl)-5-oxopyrrolidine-3-carbohydrazide derivatives bearing heterocyclic moieties were synthesized. Antioxidant activity of the synthesized compounds was screened by DPPH radical scavenging method and reducing power assay. A number of compounds were identified as potent antioxidants. Antioxidant activity of 1-(5-chloro-2-hydroxyphenyl)-4-(5-thioxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)p

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31

Jasinski, Jerry P., Ray J. Butcher, Anil N. Mayekar, B. Narayana, and H. S. Yathirajan. "(2E)-1-(2,4-Dichlorophenyl)-3-[4-(diethylamino)-2-hydroxyphenyl]prop-2-en-1-one." Acta Crystallographica Section E Structure Reports Online 63, no. 11 (2007): o4231—o4232. http://dx.doi.org/10.1107/s1600536807047666.

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In the title molecule, C19H19Cl2NO2, the angle between the mean planes of the 2,4-dichlorophenyl and 2-hydroxyphenyl groups is 81.8 (2)°. The ketone oxygen of the prop-2-en-1-one group is twisted in a synclinal conformation with the 2,4-dichlorophenyl group [torsion angle = −75.7 (2)°]. The two diethyl extensions from the 4-(diethylamino)-2-hydroxyphenyl group are twisted in anti- and syn-periplanar conformations. Crystal packing is stabilized by intermolecular C—H...O hydrogen bonding between the ketone O atom from the prop-2-en-1-one group and H atoms from both the 2-hydroxyphenyl ring and t

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32

(MRS), B.D. SARAF, and N. WADODKAR K. "Synthesis of some New 5-(2-Hydroxyphenyl)-3-methyl-4-(1- acetyl-5-aryl-2-pyrazolin-3-yl)pyrazoles and 1-Phenyl-5- (2-hydroxyphenyl)-3-methyl-4-(1-phenyl-5-aryl-2- pyrazolin-3-yl)pyrazoles." Journal of Indian Chemical Society Vol. 70, Jul 1993 (1993): 643–44. https://doi.org/10.5281/zenodo.5917738.

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Department of Chemistry, Vidarbha Mahavidylaya, Amravati-444 604 <em>Manuscript received 4 October 1991, revised 19 January 1993, accepted 1 February </em>1993 synthesis of some New 5-(2-Hydroxyphenyl)-3-methyl-4-(1- acetyl-5-aryl-2-pyrazolin-3-yl)pyrazoles and 1-Phenyl-5-Synthesis of some New 5-(2-Hydroxyphenyl)-3-methyl-4-(1-(2-hydroxyphenyl)-3-methyl-4-(1-phenyl-5-aryl-2-pyrazolin-3-yl)pyrazoles          

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33

Basappa, Basappa, Baburajeev Chumadathil Pookunoth, Mamatha Shinduvalli Kempasiddegowda, Rangappa Knchugarakoppal Subbegowda, Peter E. Lobie та Vijay Pandey. "Novel Biphenyl Amines Inhibit Oestrogen Receptor (ER)-α in ER-Positive Mammary Carcinoma Cells". Molecules 26, № 4 (2021): 783. http://dx.doi.org/10.3390/molecules26040783.

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Herein, the activity of adamantanyl-tethered-biphenyl amines (ATBAs) as oestrogen receptor alpha (ERα) modulating ligands is reported. Using an ERα competitor assay it was demonstrated that ATBA compound 3-(adamantan-1-yl)-4-methoxy-N-(4-(trifluoromethyl) phenyl) aniline (AMTA) exhibited an inhibitory concentration 50% (IC50) value of 62.84 nM and demonstrated better binding affinity compared to tamoxifen (IC50 = 79.48 nM). Treatment of ERα positive (ER+) mammary carcinoma (MC) cells (Michigan Cancer Foundation-7 (MCF7)) with AMTA significantly decreased cell viability at an IC50 value of 6.4

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34

Asgarova, Aytan R., Ali N. Khalilov, Ivan Brito, et al. "Hydrogen and halogen bonding in the haloetherification products in chalcone." Acta Crystallographica Section C Structural Chemistry 75, no. 3 (2019): 342–47. http://dx.doi.org/10.1107/s2053229619001025.

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Cooperative action of hydrogen and halogen bonding in the reaction of 3-(3,5-di-tert-butyl-4-hydroxyphenyl)-1-phenylprop-2-en-1-one with HCl or HBr in alcohol medium under microwave irradiation (20 W, 80 °C, 10 min) allows the isolation of the haloetherification products (2S,3S)-3-(3-tert-butyl-5-chloro-4-hydroxyphenyl)-2-chloro-3-ethoxy-1-phenylpropan-1-one, C21H24Cl2O3, (2S,3S)-2-bromo-3-(3-tert-butyl-5-bromo-4-hydroxyphenyl)-3-methoxy-1-phenylpropan-1-one, C20H22Br2O3, and (2S,3S)-2-bromo-3-(3-tert-butyl-5-bromo-4-hydroxyphenyl)-3-ethoxy-1-phenylpropan-1-one, C21H24Br2O3, in good yields. Bo

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35

Verkerk, Udo H., Robert McDonald, and Jeffrey M. Stryker. "Coordination chemistry of the tetrakis(2-hydroxyphenyl)ethene support mimic — Polymetallic magnesium, aluminum, and titanium derivatives." Canadian Journal of Chemistry 83, no. 6-7 (2005): 922–28. http://dx.doi.org/10.1139/v05-108.

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The crystal structures of magnesium, aluminum, and titanium coordination complexes of the structurally preorganized tetrakis(2-hydroxyphenyl)ethene are reported. As a result of the absence of steric shielding and the conformational flexibility of the ligand, pseudo-dimeric complexes are formed instead of crown- or raft-like compounds. The unsubstituted tetrakis(2-hydroxyphenyl)ethene ligand thus emulates the complexation characteristics of the sterically open calix[4]arene system.Key words: coordination chemistry, polymetallic, titanium complexes, magnesium complexes, aluminum complexes, tetra

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36

Matsumoto, Yuichiro, Yuichi Hashimoto, and Shinya Fujii. "Development of subtype-selective estrogen receptor modulators using the bis(4-hydroxyphenyl)silanol core as a stable isostere of bis(4-hydroxyphenyl)methanol." RSC Advances 13, no. 39 (2023): 27359–62. http://dx.doi.org/10.1039/d3ra04656g.

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By using a bis(4-hydroxyphenyl)silanol framework as a stable isostere of bis(4-hydroxyphenyl)methanol, we developed novel and characteristic estrogen receptor (ER) modulators exhibiting antagonist activity toward ERα and agonist activity toward ERβ.

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37

Drzewiecka, Małgorzata, Monika Beszterda, Magdalena Frańska, and Rafał Frański. "2,2-Bis(4-Hydroxyphenyl)-1-Propanol—A Persistent Product of Bisphenol A Bio-Oxidation in Fortified Environmental Water, as Identified by HPLC/UV/ESI-MS." Toxics 9, no. 3 (2021): 49. http://dx.doi.org/10.3390/toxics9030049.

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Biodegradation of bisphenol A in the environmental waters (lake, river, and sea) has been studied on the base of fortification of the samples taken and the biodegradation products have been analyzed using HPLC/UV/ESI-MS. Analysis of the characteristic fragmentation patterns of [M-H]− ions permitted unambiguous identification of the biodegradation products as 2,2-bis(4-hydroxyphenyl)-1-propanol or as p-hydroxyacetophenone, depending on the type of surface water source. The formation of 2,2-bis(4-hydroxyphenyl)-1-propanol was much more common than that of p-hydroxyacetophenone. Moreover, 2,2-Bis

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38

Escobar, Carlos A., Odette A. Alvarado, Judith A. K. Howard, and Mauricio Fuentealba. "Synthesis of N-Acylated 1,5-Benzodiazepines: Differentiation between Two Possible Acylation Sites via Hydrogen Bonding." Zeitschrift für Naturforschung B 68, no. 4 (2013): 397–402. http://dx.doi.org/10.5560/znb.2013-2338.

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Temperature-dependent regioselectivity between amino and hydroxyl groups mediated by hydrogen bonding was observed in the reaction of acetic anhydride with 2-(2,3-dimethoxyphenyl)- 4-(2-hydroxyphenyl)-2,3-dihydro-1H-1,5-benzodiazepine (1), obtaining 1-acetyl-2-(2,3-dimethoxyphenyl)- 4-(2-hydroxyphenyl)-2,3-dihydro-1H-1,5-benzodiazepine (1a), when these were reacted at room temperature, and 4-(2-acetoxyphenyl)-1-acetyl-2-(2,3-dimethoxyphenyl)-2,3-dihydro-1H-1,5- benzodiazepine (1b), when they were refluxed (148 - 150 °C). Acylation of the less hindered analog 4-(2-hydroxyphenyl)-2-phenyl-2,3-di

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39

Li, Nana, Guowei Jiang, and Guangyuan Zhou. "Synthesis and characterization of a cyclic 9,9-bis(4-hydroxyphenyl)fluorine (phenylene phosphonate) oligomer and its flame retardancy application." RSC Advances 5, no. 96 (2015): 78815–22. http://dx.doi.org/10.1039/c5ra15404a.

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A novel solid flame retardant cyclic 9,9-bis(4-hydroxyphenyl)fluorine (phenylene phosphonate) (CPFP) oligomer was synthesized in high yields by the reaction of phenylphosphonic dichloride with 9,9-bis(4-hydroxyphenyl)fluorine under pseudo-high-dilution conditions.

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40

Waruwu, Syukur Berkat, Urip Harahap, Yuandani Yuandani, Hari Purnomo, and Denny Satria. "Anti-inflammatory activity and toxicity evaluation of 1,3-bis(p-hydroxyphenyl)urea." F1000Research 11 (September 20, 2022): 418. http://dx.doi.org/10.12688/f1000research.77443.2.

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Background: Inflammation is a normal protective response caused by tissue damage through physical trauma, chemical damage, or invasion of pathogenic microorganisms. 1,3-bis(p-hydroxyphenyl)urea is a modified p-aminophenol compound, which is considered to have strong analgesic activity based on cyclooxygenase-2 inhibition and has fewer hepatotoxic side effects. In-silico test showed 1,3-bis(p-hydroxyphenyl)urea has COX-1 and TNF- binding activity, so it has the potential to be developed as an anti-inflammatory agent. Anti-inflammatory activity was tested using mice. Toxicity test was conducted

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41

Deacon, Glen B., Peter C. Junk, Winnie W. Lee, Maria Forsyth, and Jun Wang. "Rare earth 3-(4′-hydroxyphenyl)propionate complexes." New Journal of Chemistry 39, no. 10 (2015): 7688–95. http://dx.doi.org/10.1039/c5nj00787a.

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Structural variation of lanthanoid 3-(4′-hydroxyphenyl)propionates and investigation of the anti-corrosion properties of lanthanum 3-(4′-hydroxyphenyl)propionate are presented, highlighting lanthanoid contraction and the importance of the –CHCH− structural unit of 4-hydroxycinnamates in corrosion mitigation.

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42

Zikmundová, M., K. Drandarov, L. Bigler, M. Hesse, and C. Werner. "Biotransformation of 2-Benzoxazolinone and 2-Hydroxy-1,4-Benzoxazin-3-one by Endophytic Fungi Isolated from Aphelandra tetragona." Applied and Environmental Microbiology 68, no. 10 (2002): 4863–70. http://dx.doi.org/10.1128/aem.68.10.4863-4870.2002.

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ABSTRACT The biotransformation of the phytoanticipins 2-benzoxazolinone (BOA) and 2-hydroxy-1,4-benzoxazin-3-one (HBOA) by four endophytic fungi isolated from Aphelandra tetragona was studied. Using high-performance liquid chromatography-mass spectrometry, several new products of acylation, oxidation, reduction, hydrolysis, and nitration were identified. Fusarium sambucinum detoxified BOA and HBOA to N-(2-hydroxyphenyl)malonamic acid. Plectosporium tabacinum, Gliocladium cibotii, and Chaetosphaeria sp. transformed HBOA to 2-hydroxy-N-(2-hydroxyphenyl)acetamide, N-(2-hydroxyphenyl)acetamide, N-

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43

Zhang, Songyan, Yunfeng Wang, Haopeng Zhang, Chengming Sun, Shuwei Dang та Ming Liu. "Hydroxyphenyl Butanone Induces Cell Cycle Arrest through Inhibition of GSK3β in Colorectal Cancer". BioMed Research International 2021 (3 липня 2021): 1–13. http://dx.doi.org/10.1155/2021/9981815.

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Background. Colorectal cancer (CRC) is among the top three gastrointestinal malignancy in morbidity and mortality. The abnormal activation of Wnt/β-catenin pathway is considered to be a key factor in the occurrence and development of CRC. Novel inhibitor discovery against key factor in WNT pathway is important for CRC treatment and prevention. Methods. Cell proliferation was detected after hydroxyphenyl butanone treatment in human colorectal cancer HCT116, LOVO, and normal colonic epithelial NCM460 cells. Colony formation, cell invasion ability, and cell cycle were detected with and without GS

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44

Yunita Prabawati, Susy, Damayanti Iskandar, and Liimroati Purwo Suci. "The Synthesis and Evaluation of Vanillin derivatives as the Fruit Fly Attractant." Oriental Journal of Chemistry 34, no. 4 (2018): 2197–202. http://dx.doi.org/10.13005/ojc/3404063.

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The present study was conducted to synthesize 4-(4-hydroxyphenyl-3-methoxy)-4-hydroxy-2-butanone, a compound with similar structure to cue lure [4-(4-Acetyoxyphenyl)-2-butanone], using vanillin as a started material. The synthesis process was completed in two steps. The first step was the condensation reaction of Claisen Smidth between vanillin and acetone on alkaline conditions to produce 4-(4-hydroxyphenyl-3-methoxy)-3-buten-2-one, and the second step was the hydration reaction using zeolite catalysts activated by HCl, to produce 4-(4-hydroxyphenyl-3-methoxy)-4-hydroxy-2-butanone. Characteri

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45

Pradika, Yuri, Deni Pranowo, and Sabirin Matsjeh. "Synthesis of 4-(5-Bromo-4-Hydroxyphenyl-3-Methoxy)-2-Butanone and the Activity Test as Fruit Flies Attractant." Key Engineering Materials 840 (April 2020): 113–17. http://dx.doi.org/10.4028/www.scientific.net/kem.840.113.

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Synthesis of 4-(5-bromo-4-hydroxyphenyl-3-methoxy)-2-butanone and its potential test as fruit flies attractant has been done. All of products were analyzed by FT-IR GC-MS, and 1H-NMR. Synthesis of 4-(5-bromo-4-hydroxyphenyl-3-methoxy)-2-butanone was carried out in three steps reaction. First, the bromination of vanillin was performed using KBrO3 and HBr in acidic condition. Second, aldol condensation of 5-bromovanillin with acetone using base catalyst NaOH 20%. Third, 4-(5-bromo-4-hydroxyphenyl-3-methoxy)-2-butanone was synthesized by reacting the reduction reaction of condensation aldol produ

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46

Langer, Vratislav, Miroslav Koóš, Dalma Gyepesová, Mariana Sládkovičová, Jozef Lustoň, and Juraj Kronek. "Three isomeric forms of hydroxyphenyl-2-oxazoline: 2-(2-hydroxyphenyl)-2-oxazoline, 2-(3-hydroxyphenyl)-2-oxazoline and 2-(4-hydroxyphenyl)-2-oxazoline." Acta Crystallographica Section C Crystal Structure Communications 61, no. 10 (2005): o602—o606. http://dx.doi.org/10.1107/s0108270105027812.

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47

Choi, Hyun Gyu, Hwa Dong Lee, Sang Hyun Kim, Min Kyun Na, Jeong Ah Kim, and Seung Ho Lee. "Phenolic Glycosides from Lindera obtusiloba and their Anti-allergic Inflammatory Activities." Natural Product Communications 8, no. 2 (2013): 1934578X1300800. http://dx.doi.org/10.1177/1934578x1300800212.

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Eight phenolic glycosides, tachioside (1), isotachioside (2), koaburaside (3), 2,6-dimethoxy-4-hydroxyphenyl-1- O-ß-D-glucopyranoside (4), 4,6-dihydroxy-2- methoxyphenyl-1- O-β-D-glucopyranoside (5), a mixture of erigeside C (6a) and salidroside (6b), and 6-hydroxyphenyl)-1- O-β-D-glucopyranoside (7) were isolated from the stems of Lindera obtusiloba Blume. The structures of the isolates were determined by 1H-, 13C-NMR, COSY, HMQC, and HMBC spectroscopy. To evaluate their anti-allergic inflammatory activities, the inhibitory effects of isolates (1-7) on histamine release and on the gene expres

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48

van den Heuvel, Robert H. H., Marco W. Fraaije, Colja Laane, and Willem J. H. van Berkel. "Regio- and Stereospecific Conversion of 4-Alkylphenols by the Covalent Flavoprotein Vanillyl-Alcohol Oxidase." Journal of Bacteriology 180, no. 21 (1998): 5646–51. http://dx.doi.org/10.1128/jb.180.21.5646-5651.1998.

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ABSTRACT The regio- and stereospecific conversion of prochiral 4-alkylphenols by the covalent flavoprotein vanillyl-alcohol oxidase was investigated. The enzyme was active, with 4-alkylphenols bearing aliphatic side chains of up to seven carbon atoms. Optimal catalytic efficiency occurred with 4-ethylphenol and 4-n-propylphenols. These short-chain 4-alkylphenols are stereoselectively hydroxylated to the corresponding (R)-1-(4′-hydroxyphenyl)alcohols (F. P. Drijfhout, M. W. Fraaije, H. Jongejan, W. J. H. van Berkel, and M. C. R. Franssen, Biotechnol. Bioeng. 59:171–177, 1998). (S)-1-(4′-Hydroxy

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49

Putri Aisyia Fauzi, Ziza, Urip Harahap, Yuandani Yuandani, Syukur Berkat Waruwu, Hari Purnomo, and Denny Satria. "Toxic Effect Of The Compound {1,3 Bis (P-Hydroxyphenyl) Urea} On Triiodothyronine (T3) Hormone Levels In Pregnant White Rats (Rattus Norvegicus L.)." International Journal of Science, Technology & Management 4, no. 1 (2023): 269–72. http://dx.doi.org/10.46729/ijstm.v4i1.719.

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Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most commonly prescribed drugs for pregnant women to treat fever, pain and inflammation. Specific NSAIDs can displace thyroid hormone from its protein binding sites, causing thyroid hormone measurement problems. {1,3 bis (p-Hydroxyphenyl)urea} is a modified p-aminophenol compound with potent analgesic and anti-inflammatory activity and less toxicity. This study is a follow-up to previous research to observe the toxic effect on triiodothyronine hormone levels after administration of {1,3 bis(p-Hydroxyphenyl)urea} compound in pregnant

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50

Koma, Daisuke, Hayato Yamanaka, Kunihiko Moriyoshi, Takashi Ohmoto, and Kiyofumi Sakai. "Production of Aromatic Compounds by Metabolically Engineered Escherichia coli with an Expanded Shikimate Pathway." Applied and Environmental Microbiology 78, no. 17 (2012): 6203–16. http://dx.doi.org/10.1128/aem.01148-12.

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ABSTRACTEscherichia coliwas metabolically engineered by expanding the shikimate pathway to generate strains capable of producing six kinds of aromatic compounds, phenyllactic acid, 4-hydroxyphenyllactic acid, phenylacetic acid, 4-hydroxyphenylacetic acid, 2-phenylethanol, and 2-(4-hydroxyphenyl)ethanol, which are used in several fields of industries including pharmaceutical, agrochemical, antibiotic, flavor industries, etc. To generate strains that produce phenyllactic acid and 4-hydroxyphenyllactic acid, the lactate dehydrogenase gene (ldhA) fromCupriavidus necatorwas introduced into the chro

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