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Journal articles on the topic 'Hydroxypropyl methylcellulose (HPMC)'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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1

Hamed, Othman, Rana Al-Kerm, Rola Al-Kerm, Hisham Qrareya, Abdalhadi Deghles, and Omar Dagdag. "Carboxymethylated pulp as starting point to prepare hydroxypropylmethyl cellulose with enhanced gel rheological properties in an aqueous medium." BioResources 16, no. 1 (2021): 1453–68. http://dx.doi.org/10.15376/biores.16.1.1453-1468.

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Hydroxypropyl methylcellulose in an aqueous solution upon heating tends to undergo thermal gelation, where the polymer chains form a network and precipitate from solution. This occurs at a temperature known as thermal gelation point. Polymer precipitation causes a significant drop in the shear viscosity. This could be a disadvantage in a hot environment or in applications were heat is applied. In this work, a hydroxypropylmethyl cellulose (HPMC) was formed that undergoes thermal gelation with no polymer precipitation and with enhanced rheological properties. The target HPMC was prepared from w

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Mahdavinia, Gholam Reza, Sanaz Ettehadi, Mojtaba Amini, and Mohammad Sabzi. "Synthesis and characterization of hydroxypropyl methylcellulose-g-poly(acrylamide)/LAPONITE® RD nanocomposites as novel magnetic- and pH-sensitive carriers for controlled drug release." RSC Advances 5, no. 55 (2015): 44516–23. http://dx.doi.org/10.1039/c5ra03731j.

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Kumar, Sunil, Sandeep Dongre, Raghu S, T. Demappa, and J. Sannappa. "Structural and Mechanical characteristic study of HPMC polymer composite films." IOP Conference Series: Materials Science and Engineering 1221, no. 1 (2022): 012011. http://dx.doi.org/10.1088/1757-899x/1221/1/012011.

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Abstract Hydroxypropyl methylcellulose (HPMC) were extensively known material in packaging, agriculture, medicine, electrolytes in solid state batteries and other areas due to the exceptional biocompatibility and easy production, however shows lower mechanical behaviour. The current investigation was embraced to delineate the effect of potassium iodide (KI) on structural and mechanical properties of biopolymer electrolyte films grounded on Hydroxypropyl methylcellulose (HPMC). The liquidation of the salt into the polymer crowd is done by solution cast technique and the X – Ray diffraction (XRD

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4

Harfmann, Robert G., Balasaheb K. Deshmukh, Jerry Conklin, et al. "Determination of Methylcellulose and Hydroxypropyl Methylcellulose Food Gums in Food and Food Products: Collaborative Study." Journal of AOAC INTERNATIONAL 90, no. 3 (2007): 786–93. http://dx.doi.org/10.1093/jaoac/90.3.786.

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Abstract A collaborative study was performed to determine the reproducibility of a method for the determination of methylcellulose (MC) and hydroxypropyl methylcellulose (HPMC) in food. These widely used food gums possess unusual solubility characteristics and cannot accurately be determined by existing dietary fiber methods. The new method uses the enzyme-digestion procedure of AOAC Official Method 991.43. Digestate solutions must be refrigerated to fully hydrate MC or HPMC. The chilled solutions are filtered and analyzed by size-exclusion liquid chromatography. Collaborating laboratories rec

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Okechi Arukalam, Innocent, Innocent Chimezie Madufor, Okoro Ogbobe, and Emeka E. Oguzie. "Hydroxypropyl methylcellulose as a polymeric corrosion inhibitor for aluminium." Pigment & Resin Technology 43, no. 3 (2014): 151–58. http://dx.doi.org/10.1108/prt-05-2013-0037.

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Purpose – The paper aims to investigate the effectiveness of hydroxypropyl methylcellulose (HPMC) as corrosion inhibitor for aluminium in 0.5 M H2SO4 solution. Design/methodology/approach – This study was carried out using weight loss and electrochemical techniques. Inhibition efficiency was determined by comparing the corrosion rates in the absence and presence of inhibitor system. Quantum chemical computations were performed using density functional theory to assess the parameters responsible for the inhibition process and also to analyse the local reactivity of the molecule. Findings – HPMC

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6

Hamdi, Dalia S., Masar B. M. Mohamed, and Saja M. Mansour. "Preparation and Characterization of Hydroxypropyl methylcellulose Gastroretentive Film using Metoclopramide HCl." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 12, no. 04 (2022): 1831–37. http://dx.doi.org/10.25258/ijddt.12.4.57.

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This study aimed to formulate a gastro retentive slow release dosage form based on oral film for metoclopramide hydrochloric acid (HCl), a medication with a narrow absorption window. The gastroretentive film was made using a solvent casting method with varying ratios of primary polymers (HPMC 15000 cps and HPMC K4M), secondary polymer (carbopol 934), and PEG-400 as a plasticizer. The film of hydroxypropyl methylcellulose (HPMC) K4M-3 (50:50) (HPMC K4M: carbopol) was buoyant for 20 minutes. The 52 wt % of metoclopramide HCl (metclo) was released from the HPMC K4M-3 film after 24 hours, and its

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7

Pang, Haosheng, Jianxun Xu, Huan Liu, et al. "The Induced Orientation of Hydroxypropyl Methylcellulose Coating for Ultralow Wear." Lubricants 12, no. 4 (2024): 129. http://dx.doi.org/10.3390/lubricants12040129.

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This study investigated the frictional properties of HPMC under different load and concentration conditions through friction experiments and surface characterization. The study aimed to explore and reveal the influence of load and concentration on the frictional properties of HPMC, as well as its anti−wear mechanism. The results of the study indicated that under the same solution concentration, the effect of load on the friction coefficient of HPMC was not significant. Specifically, for samples with low concentration (C−0.2), the wear ratio of HPMC under a 4 N load (1.01 × 10−11 mm3·N−1·m−1) w

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8

Wang, Jiyang, Dan Yu, Chen Zeng, et al. "Effect of Textile Layers and Hydroxypropyl Methylcellulose on Flexural Behavior of TRLC Thin Plates." Buildings 14, no. 4 (2024): 924. http://dx.doi.org/10.3390/buildings14040924.

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To examine the flexural toughness characteristics of textile-reinforced lightweight aggregate concrete (TRLC), a four-point bending test was conducted to assess the impact of varying numbers of textile layers and the inclusion of hydroxypropyl methylcellulose on the ultimate load-bearing capacity and deformation capacity of TRLC thin plates. Six groups of specimens were prepared for the experiment, and the bending capacity of the thin plates in each group was evaluated. The flexural toughness index was utilized to quantify the bending performance of TRLC thin plates. The findings revealed that

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9

Pandit, Ashlesha Pravin, and Rajendra Dattatray Shinde. "Development and in vitro evaluation of sustained release multiparticulate tablet of freely water soluble drug." Brazilian Journal of Pharmaceutical Sciences 46, no. 3 (2010): 463–71. http://dx.doi.org/10.1590/s1984-82502010000300009.

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Blends of aqueous dispersion of a hydrophobic and hydrophilic polymer, namely Surelease®: hydroxypropyl methylcellulose (Surelease®: HPMC E15) were used as coating materials to control the drug release from coated pellets of the highly water soluble drug metoprolol succinate. Varying the polymer blends, ranges of drug release patterns were obtained at pH 6.8. The present study dealt with diffusion of drug through plasticized Surelease®/ hydroxypropyl methylcellulose (HPMC E15) films prepared by coating of drug and polymers onto non-pareil seeds using the solution layering technique. The releas

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10

Cavalheiro Maeda, Vinicius, Cintia Marques Correa, Marcos Henrique Mamoru Otsuka Hamanaka, Viviane Nogueira Hamanaka, Celso Molina, and Fernanda F. Camilo. "Electrical and mechanical properties of self-supported hydroxypropyl methylcellulose–polyaniline conducting films." RSC Advances 13, no. 12 (2023): 7913–20. http://dx.doi.org/10.1039/d3ra00916e.

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The purpose of this work was to develop a simple method to produce self-supported films composed of hydroxypropyl methylcellulose (HPMC) and polyaniline (PANI) by the direct mixture of aqueous dispersions of both polymers with subsequent drying.

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11

Kampa, Jansuda, Richard Frazier, and Julia Rodriguez-Garcia. "Development of Saturated Fat Replacers: Conventional and Nano-Emulsions Stabilised by Lecithin and Hydroxylpropyl Methylcellulose." Foods 11, no. 16 (2022): 2536. http://dx.doi.org/10.3390/foods11162536.

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The combination of two emulsifiers, lecithin and hydroxypropyl methylcellulose (HPMC), into emulsions is an interesting strategy to design fat replacers in food matrices. The objective of this study was to investigate the effect of HPMC type and concentration on the formation, stability, and microstructure of conventional emulsions and nanoemulsions. Two different types of HPMC with low and high content of methyl and hydroxypropyl groups (HPMC-L and HPMC-H) were evaluated. The results showed that the molecular structure and concentration of HPMC play a major role in the viscoelastic behaviour,

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12

Viswanad, Vidya. "FORMULATION AND EVALUATION OF NOVEL CHROMENE DERIVATIVE AS AN ANTI INFLAMMATORY AGENT USED FOR IBD." Asian Journal of Pharmaceutical and Clinical Research 10, no. 2 (2017): 319. http://dx.doi.org/10.22159/ajpcr.2017.v10i2.15696.

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Objective: To formulate and evaluate an extended-release (ER) tablet of a new molecule, 2-amino-4-(4-bromophenyl)-7-hydroxy-4H-chromene-3- carbonitrile using a combination of two polymers (hydroxypropyl methyl cellulose [HPMC] K100 and HPMC phthalate) which control the rate and degree of the drug release through 12 hrs period and protect the drug release from acidic pH.Methods: Five batches of tablets (4HC1, 4HC2, 4HC3, 4HC4, 4HC5) were produced by direct compression method. Morphological evaluation of the powder blend was carried out by differential scanning calorimetry and Powered X-ray diff

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13

Muna, Aulal, Rumpoko Wicaksono, and Condro Wibowo. "Characterization of Layer-by-Layer Biodegradable Films Based on Hydroxypropyl Methylcellulose-Nanochitosan." Journal of Applied Food Technology 10, no. 2 (2023): 37–47. http://dx.doi.org/10.17728/jaft.20868.

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This research investigates the physical and optical properties of single-layer and layer-by-layer biodegradable films composed of hydroxypropyl methylcellulose (HPMC) and nanochitosan. Initially, HPMC and nanochitosan were formulated as single layers at various concentrations, and subsequently, the selected formulas were utilized to produce a layer-by-layer film. The results indicate that the concentrations of 0.4% w/v HPMC and 0.5% w/v of nanochitosan were successfully assembled into a layer-by-layer biodegradable film. Assessment based on multiple parameters (thickness, moisture content, wat

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14

Zhang, Liang, Li-Na Yue, Jian-Ya Qian, and Xiang-Li Ding. "Effect of Curdlan on the Rheological Properties of Hydroxypropyl Methylcellulose." Foods 10, no. 1 (2020): 34. http://dx.doi.org/10.3390/foods10010034.

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This work focuses on the effect of curdlan (CL) on dynamic viscoelastic property, thermal reversible property, viscosity, and the fluid types of hydroxypropyl methylcellulose (HPMC) at different temperatures. Compared to the blends at 25 °C, the blends had a smaller linear viscoelastic region (LVR), a higher gel strength, and larger storage modulus (G’) and loss modulus (G”) values at 82 °C. G’, G”, gel strength, and viscosity increased with the increase of CL. Repeated temperature sweep led to increased G’ and G” of HPMC/CL blends. For HC6 and HC8, the gel formation temperature of the repeate

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15

Olorunsola, Emmanuel O., and Stephen O. Majekodunmi. "Development of extended-release formulation of domperidone using a blend of Raphia hookeri gum and hydroxypropyl methylcellulose as tablet matrix." Tropical Journal of Pharmaceutical Research 16, no. 10 (2017): 2341–47. http://dx.doi.org/10.4314/tjpr.v16i10.5.

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Purpose: To develop an extended-release formulation of domperidone using a blend of Raphia hookeri gum and hydroxypropyl methylcellulose as tablet matrix.Methods: Tablets (400 mg) containing 30 mg domperidone (DPD) were formulated using binary mixtures of hydroxypropyl methylcellulose (HPMC) and Raphia hookeri gum (RHG) as matrix former; and microcrystalline cellulose (MCC) as direct compression excipient. The proportions of the matrix formers (40 % of tablet weight) was varied as 100:0, 75:25, 50:50, 25:75 and 0:100. The composition of the matrix former was also kept constant (50:50) while MC

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16

He, Jianfei, Huai-Yu Chen, Hongbin Chen, Baobei Wang, Fengxian Guo, and Zong-Ping Zheng. "Characterization, Stability, and Antibrowning Effects of Oxyresveratrol Cyclodextrin Complexes Combined Use of Hydroxypropyl Methylcellulose." Foods 11, no. 16 (2022): 2471. http://dx.doi.org/10.3390/foods11162471.

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Oxyresveratrol (Oxy) has attracted much attention by employing it as an antibrowning agent in fruits and vegetables. In this study, the formation of cyclodextrin (CD) inclusion exhibited a certain protective effect on Oxy oxidative degradation, while hydroxypropyl-β-cyclodextrin (HP–β-CD) inclusion complex showed stronger stabilizing effects than those of β-cyclodextrin (β-CD). The combined use of CD and hydroxypropyl methylcellulose (HPMC) greatly improved the stability of Oxy–CD inclusion complexes, with approximately 70% of the trans-Oxy retained after 30 days of storage under light conditi

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17

Vlad, Robert-Alexandru, Andrada Pintea, Cezara Pintea, et al. "Hydroxypropyl Methylcellulose—A Key Excipient in Pharmaceutical Drug Delivery Systems." Pharmaceutics 17, no. 6 (2025): 784. https://doi.org/10.3390/pharmaceutics17060784.

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Hydroxypropyl methylcellulose (Hypromellose, HPMC) is a well-known excipient used in the pharmaceutical and nutraceutical fields due to its versatile physicochemical properties. HPMC (derived from cellulose and obtained through etherification) varies in polymerization degree and viscosity, factors that both influence its functional applications. Usually, an increased polymerization degree implies a higher viscosity, depending also on the amount of polymer used. Hypromellose plays a crucial role in solid dosage forms, serving as a binder in the case of controlled-release tablets, a film-forming

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18

Kvitek, Ondrej, Elizaveta Mutylo, Barbora Vokata, et al. "Photochemical Preparation of Silver Colloids in Hydroxypropyl Methylcellulose for Antibacterial Materials with Controlled Release of Silver." Coatings 10, no. 11 (2020): 1046. http://dx.doi.org/10.3390/coatings10111046.

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Silver nanoparticles (AgNPs) possess strong antibacterial effect. The current trend is to incorporate AgNPs into functional materials that benefit from their bactericidal capabilities. Hydroxypropyl methylcellulose (HPMC) is routinely used for the controlled release of medicine thanks to its slow dissolution in water and could be used as a matrix for the controlled release of AgNPs, if a method to produce such a material without the need of other reactants was developed. We proposed such a method in a photochemical reduction of AgNO3 in hydroxypropyl methylcellulose (HPMC) solutions by the ill

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19

Cao, Xu, Yinqiu Wang, Yu Zhang, Zenghui Qian, and Guodong Jiang. "Preparation and Properties of Polyaniline/Hydroxypropyl Methylcellulose Composite Conductive Thin Films." Materials 17, no. 11 (2024): 2687. http://dx.doi.org/10.3390/ma17112687.

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In this work, a chemical grafting polymerization method was employed to synthesize EHPMC-g-PANI self-supporting films. Polyaniline (PANI) was grafted onto hydroxypropyl methylcellulose (HPMC) modified with epichlorohydrin (EPHMC) to obtain an EHPMC-g-PANI aqueous dispersion, which was subsequently dried to form the self-supporting films. The introduction of HPMC, with its excellent film-forming ability and mechanical strength, successfully addressed the poor film-forming ability and mechanical properties intrinsic to PANI. Compared to in situ polymerized HPMC/PANI, the EHPMC-g-PANI exhibited s

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20

Leyk, Edyta, and Marek Wesolowski. "Miscibility and Solubility of Caffeine and Theophylline in Hydroxypropyl Methylcellulose." Pharmaceutics 13, no. 11 (2021): 1836. http://dx.doi.org/10.3390/pharmaceutics13111836.

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As amorphization may improve the solubility and bioavailability of a drug substance, the aim of this work was to assess to what extent the crystallinity of caffeine (CAF) and theophylline (TF) can be reduced by homogenization with a polymeric excipient. To realize this purpose, the physical mixtures of both methylxanthines with hydroxypropyl methylcellulose (HPMC) were examined using differential scanning calorimetry (DSC), hot-stage microscopy (HSM), Fourier-transform infrared (FTIR) and Raman spectroscopy. Moreover, phase diagrams for the physical mixtures were calculated using theoretical d

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21

Guo, Jintao, Shuting Dong, Mengyu Ye та ін. "Effects of Hydroxypropyl Methylcellulose on Physicochemical Properties and Microstructure of κ-Carrageenan Film". Foods 11, № 19 (2022): 3023. http://dx.doi.org/10.3390/foods11193023.

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We investigated the effects of different proportions of hydroxypropyl methylcellulose (HPMC) on the properties of κ-carrageenan film. Biodegradable κ-carrageenan/HPMC films (κCHM film) were prepared by the solution casting method and their physicochemical properties were evaluated. The results show that the addition of HPMC enhanced oxygen barrier capacity, mechanical properties (tensile strength and elongation at break) and thermal stability. Notably, when the addition of HPMC increased to 6% of κ-carrageenan (w:w), the κCHM-6 film not only effectively improved water resistance, including low

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22

Kumar Srivastava, Ashish, and Ankit Pratap. "Compounds of Hydroxypropyl Methylcellulose with Carbon Nanotubes: Synthesis and Analysis." Journal of Futuristic Sciences and Applications 3, no. 2 (2020): 39–45. http://dx.doi.org/10.51976/jfsa.322004.

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The business has developed an interest in aqueous injectable, undisturbed gel-forming solutions with a range of properties, particularly in the field of tissue engineering. In-situ gel-forming matrix may be injected into the afflicted regions without the need for surgery. Second, it may be introduced as growth factors and medications by just mixing them together, without any issues with the leftover solvents that are often used in scaffolds, and it quickly adapts to the environment after being introduced. As a result, multi-walled carbon nanotubes that had undergone acid functionalization had

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23

Lim, Li Ming, and Kunn Hadinoto. "High-Payload Buccal Delivery System of Amorphous Curcumin–Chitosan Nanoparticle Complex in Hydroxypropyl Methylcellulose and Starch Films." International Journal of Molecular Sciences 22, no. 17 (2021): 9399. http://dx.doi.org/10.3390/ijms22179399.

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Oral delivery of curcumin (CUR) has limited effectiveness due to CUR’s poor systemic bioavailability caused by its first-pass metabolism and low solubility. Buccal delivery of CUR nanoparticles can address the poor bioavailability issue by virtue of avoidance of first-pass metabolism and solubility enhancement afforded by CUR nanoparticles. Buccal film delivery of drug nanoparticles, nevertheless, has been limited to low drug payload. Herein, we evaluated the feasibilities of three mucoadhesive polysaccharides, i.e., hydroxypropyl methylcellulose (HPMC), starch, and hydroxypropyl starch as buc

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24

Zupanc, Andraž, Martin Petkovšek, Blaž Zdovc, Ema Žagar, and Mojca Zupanc. "Degradation of hydroxypropyl methylcellulose (HPMC) by acoustic and hydrodynamic cavitation." Ultrasonics Sonochemistry 109 (October 2024): 107020. http://dx.doi.org/10.1016/j.ultsonch.2024.107020.

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25

Ding, Cuicui, Min Zhang, and Guoying Li. "Preparation and characterization of collagen/hydroxypropyl methylcellulose (HPMC) blend film." Carbohydrate Polymers 119 (March 2015): 194–201. http://dx.doi.org/10.1016/j.carbpol.2014.11.057.

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26

Sharma, Payal, Sameer R. Modi, and Arvind K. Bansal. "Co-processing of hydroxypropyl methylcellulose (HPMC) for improved aqueous dispersibility." International Journal of Pharmaceutics 485, no. 1-2 (2015): 348–56. http://dx.doi.org/10.1016/j.ijpharm.2015.03.036.

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27

Ding, Cuicui, Min Zhang, and Guoying Li. "Rheological properties of collagen/hydroxypropyl methylcellulose (COL/HPMC) blended solutions." Journal of Applied Polymer Science 131, no. 7 (2013): n/a. http://dx.doi.org/10.1002/app.40042.

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28

Tang, Bei, Xue Gang Luo, Xiao Yan Lin, and Fang Wei Qi. "Study on Aqueous Viscosity Behaviors of Hydroxypropyl Methylcellulose Hydrosol and Konjac Glucomanan Hydrosol." Materials Science Forum 804 (October 2014): 51–54. http://dx.doi.org/10.4028/www.scientific.net/msf.804.51.

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In this work, the viscosity behavior of hydroxypropyl methylcellulose (HPMC) and konjac glucomanan (KGM) hydrosol was studied. Effects of mass fractions, water quality and sodium chloride (NaCl) on the viscosity of hydrosol were investigated by rotating viscometer. The results indicated that the viscosity of KGM and HPMC apparently increased with the increasing of mass fraction. HPMC could always maintain high viscosity in various kinds of water, whereas the viscosity of KGM reduced in tap water. The salt resistance experiments shown that the viscosities of the two kinds of hydrosol with 0.9%

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29

Wei, Wang, Yangguang Li, Ningning Tian, et al. "Effects of Dipentaerythritol and Cellulose as Additives on the Morphology of Pentaerythritol Crystals." Crystals 14, no. 3 (2024): 219. http://dx.doi.org/10.3390/cryst14030219.

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The crystal habit of pentaerythritol (PE) crystals is usually rod-shaped, which may lead to low bulk density and bad flowability compared with low aspect ratio crystals. In this study, dipentaerythritol (DPE), methylcellulose (MC), and hydroxypropyl methylcellulose (HPMC) were selected as additives to modify the morphology of PE crystals. In the presence of DPE, the bulk density of PE crystals was improved, and the aspect ratio was decreased. The modified attachment energy (AE) model was conducted to analyze changes in PE crystal habits in the presence of DPE, which characterizes the intensity

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30

Soulimane, Ilyas, Abderrahmane Khechekhouche, and Ali Farik. "Influence of hydroxypropyl methylcellulose on the mechanical properties of cement mortar reinforced by sawdust." STUDIES IN ENGINEERING AND EXACT SCIENCES 5, no. 3 (2024): e12490. https://doi.org/10.54021/seesv5n3-036.

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This study explores the incorporation of Hydroxypropyl Methylcellulose (HPMC) and sawdust into cement mortar, focusing on their effects on the setting time and mechanical properties, such as compressive and flexural strengths. Various formulations were prepared by adding different proportions of HPMC (1% and 2%) and sawdust (2%) to a standard cement mortar mix. The setting time was assessed using the Vicat apparatus, while the compressive and flexural strengths were evaluated at 7, 14, 21, and 28 days of curing. Results showed that the addition of HPMC significantly improved the mortar's perfo

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Adrover, Alessandra, Gabriele Varani, Patrizia Paolicelli, et al. "Experimental and Modeling Study of Drug Release from HPMC-Based Erodible Oral Thin Films." Pharmaceutics 10, no. 4 (2018): 222. http://dx.doi.org/10.3390/pharmaceutics10040222.

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In this work hydroxypropyl methylcellulose (HPMC) fast-dissolving thin films for oral administration are investigated. Furosemide (Class IV of the Biopharmaceutical Classification System) has been used as a model drug for in vitro release tests using three different set-ups: the Franz cell, the millifluidic flow-through device, and the paddle type dissolution apparatus (USP II). In order to enable drug incorporation within HPMC films, a multifunctional excipient, hydroxypropyl- β -cyclodextrin (HP- β -CD) has been included in the formulation, and the influence of HP- β -CD on film swelling, er

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Bashir, Sidra, Nadiah Zafar, Noureddine Lebaz, Asif Mahmood, and Abdelhamid Elaissari. "Hydroxypropyl Methylcellulose-Based Hydrogel Copolymeric for Controlled Delivery of Galantamine Hydrobromide in Dementia." Processes 8, no. 11 (2020): 1350. http://dx.doi.org/10.3390/pr8111350.

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The study aims to prepare a smart copolymeric for controlled delivery of Galantamine hydrobromide. The synthesis of the hydrogel was executed through free radical polymerization using HPMC (Hydroxypropyl methylcellulose) and pectin as polymers and acrylic acid as monomer. Cross-linking was performed by methylene bisacrylamide (MBA). HPMC-pectin-co-acrylic acid hydrogel was loaded with Galantamine hydrobromide (antidementia drug) as a model drug for treatment of Alzheimer based dementia. Formulated hydrogels (SN1–SN9) were characterized for Fourier transform-infrared spectroscopy, differential

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33

Arukalam, I. O. "Inhibiting potential of hydroxypropyl methylcellulose on acid corrosion of mild steel and aluminium." Pigment & Resin Technology 43, no. 6 (2014): 394–404. http://dx.doi.org/10.1108/prt-07-2013-0059.

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Purpose The aim of this paper is to appraise the inhibiting potential of hydroxypropyl methylcellulose (HPMC) on the corrosion of mild steel and aluminium in sulphuric and hydrochloric acid solutions. Design/methodology/approach The effects of two different corrodents on the dissolution of mild steel and aluminium were examined. Corrosion rates were determined using the weight loss technique. Inhibition efficiency was estimated by comparing the corrosion rates in absence and presence of the additive. The kinetics and mechanism of HPMC adsorption were investigated by impedance study while the a

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34

Kraisit, Pakorn, Manee Luangtana-Anan, and Narong Sarisuta. "Effect of Various Types of Hydroxypropyl Methylcellulose (HPMC) Films on Surface Free Energy and Contact Angle." Advanced Materials Research 1060 (December 2014): 107–10. http://dx.doi.org/10.4028/www.scientific.net/amr.1060.107.

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The aim of this study was to investigate the physicochemical characteristics of various viscosity grades of hydroxypropyl methylcellulose (HPMC) for mucoadhesive buccal films. The HPMC used in this study was K4M, K15M and K100M which their viscosity were 4000, 15000 and 100000 mPas respectively. Using HPMC as film forming base matrix, all intrinsic characteristics of each HPMC grade is required as basic knowledge for the development of mucoadhesive buccal films. To understand the primary essential parameters, surface free energy and contact angle of various HPMC grades were determined. Sessile

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35

Hiratsuka, Hiroyuki, Xiangyu Tao, Yuki Tokunaga, and Hiroshi Nonaka. "Properties of wood powder sheets extruded with hydroxypropyl methylcellulose and citric acid after heating." BioResources 20, no. 1 (2025): 1900–1914. https://doi.org/10.15376/biores.20.1.1900-1914.

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Plastic products generally have excellent thermal plasticity and water resistance. However, their adverse environmental effects have become a severe problem. To overcome these problems, a 100% plant-derived plastic substitute material was developed by mixing wood powder, hydroxypropyl methylcellulose (HPMC), and citric acid solution, followed by vacuum extrusion and heating to insolubilize the HPMC. In this study, the effect of heating on physical properties was investigated. The extruded wood powder sheets were heated under a wide range from 0.5 to 5 h at 150 to 210 °C, which covers the condi

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Pańtak, Piotr, Ewelina Cichoń, Joanna Czechowska, and Aneta Zima. "Influence of Natural Polysaccharides on Properties of the Biomicroconcrete-Type Bioceramics." Materials 14, no. 24 (2021): 7496. http://dx.doi.org/10.3390/ma14247496.

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In this paper, novel hybrid biomicroconcrete-type composites were developed and investigated. The solid phase of materials consisted of a highly reactive α -tricalcium phosphate (α-TCP) powder, hybrid hydroxyapatite-chitosan (HAp-CTS) material in the form of powder and granules (as aggregates), and the polysaccharides sodium alginate (SA) or hydroxypropyl methylcellulose (HPMC). The liquid/gel phase in the studied materials constituted a citrus pectin gel. The influence of SA or HPMC on the setting reaction, microstructure, mechanical as well as biological properties of biomicroconcretes was i

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Padinhattayil, Sanoop, and K. Sheshappa Rai. "Analogy and Comparative Study of Hydroxypropyl Methylcellulose (HPMC) Biopolymer with Graphene Oxide and Zinc Oxide Nano Fillers." Asian Journal of Chemistry 33, no. 7 (2021): 1513–18. http://dx.doi.org/10.14233/ajchem.2021.23193.

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Present study describes the analogy and comparative study of polymer nanocomposites with the known polymer matrix hydroxypropyl methylcellulose (HPMC) incorporated with graphene oxide (GO) and zinc oxide (ZnO) nanoparticles as nano fillers. The polymer nanocomposite films were carried out using solution casting method and characterized by IR spectroscopy, XRD analysis, mechanical properties, thermal characterization and optical microscopy analysis. There were several changes in the HPMC polymer by the addition of nanoparticles of GO and ZnO in structural, thermal, mechanical and optical proper

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Ji, Zhili, Long Yu, Qingfei Duan, et al. "Morphology and Rheology of a Cool-Gel (Protein) Blended with a Thermo-Gel (Hydroxypropyl Methylcellulose)." Foods 11, no. 1 (2022): 128. http://dx.doi.org/10.3390/foods11010128.

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This study investigates the morphological and rheological properties of blended gelatin (GA; a cooling-induced gel (cool-gel)) and hydroxypropyl methylcellulose (HPMC; a heating-induced gel (thermo-gel)) systems using a fluorescence microscope, small angle X-ray scattering (SAXS), and a rheometer. The results clearly indicate that the two biopolymers are immiscible and have low compatibility. Moreover, the rheological behavior and morphology of the GA/HPMC blends significantly depend on the blending ratio and concentration. Higher polysaccharide contents decrease the gelling temperature and im

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Zhang, Kun, Wei Yin, Xi Chen, Hui Li, Mingxing Cao, and Shengxue Zhu. "The Feasibility of Hydroxypropyl Methylcellulose as an Admixture for Porous Vegetarian Concrete Using Coarse Recycled Aggregates." Buildings 12, no. 5 (2022): 676. http://dx.doi.org/10.3390/buildings12050676.

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In this paper, hydroxypropyl methylcellulose (HPMC) is used as a new additive for porous vegetarian concrete (PVC) to improve its void structure and strength. The effect of the HPMC on the fluidity of the mortar was first investigated by a viscosity test. Then the cement hydration process was determined for analyzing the effect of the HPMC on the strength and durability of the hardened PVC. Subsequently, experiments to investigate the mass transport and compressive strength characteristics, as well as the vegetarian properties, of the concrete were carried out. The results show that the bondin

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Ortillés, Ángel, Elena Lanchares, Jose Á Cristóbal, and Begoña Calvo. "Use of 2% hydroxypropyl methylcellulose to prevent the corneal swelling during the in vitro mechanical characterization." Proceedings of the Institution of Mechanical Engineers, Part L: Journal of Materials: Design and Applications 233, no. 5 (2017): 809–16. http://dx.doi.org/10.1177/1464420717704880.

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The aim of this study was to assess the use of 2% HPMC during in vitro uniaxial tensile tests, with corneal strips immediately obtained or after storing the eyes for 24 h in 0.9% NaCl solution at 4 ℃. The purpose was to establish a standardized procedure to prevent phenomena which can modify the mechanical properties of the tissue. Rabbit eyes were divided into four groups. Group A had seven eyes that were preserved in NaCl solution for 24 h before testing. Group B had seven eyes that were immediately tested. In both groups, to prevent both swelling and dehydration, 2% hydroxypropyl methylcell

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de Silva, D. Julian, and Jane M. Olver. "Hydroxypropyl Methylcellulose (HPMC) Lubricant Facilitates Insertion of Porous Spherical Orbital Implants." Ophthalmic Plastic & Reconstructive Surgery 21, no. 4 (2005): 301–2. http://dx.doi.org/10.1097/01.iop.0000170417.19223.6c.

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Yang, Hyun Seok, and Dong Wuk Kim. "Fabrication of Gastro-Floating Famotidine Tablets: Hydroxypropyl Methylcellulose-Based Semisolid Extrusion 3D Printing." Pharmaceutics 15, no. 2 (2023): 316. http://dx.doi.org/10.3390/pharmaceutics15020316.

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Semisolid extrusion (SSE) three-dimensional (3D) printing uses drug-loaded paste for the printing process, which is capable of constructing intricate 3D structures. This research presents a unique method for fabricating gastro-floating tablets (GFT) using SSE. Paste-loaded famotidine with a matrix made of hydroxypropyl methylcellulose (HPMC) were prepared. Nine 3D printed tablets were developed with different HPMC concentrations and infill percentages and evaluated to determine their physicochemical properties, content uniformity, dissolution, and floating duration. The crystallinity of the dr

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Burcel, Miruna Gabriela, Catalina Corbu, Valeria Coviltir, et al. "Corneal Crosslinking in Progressive Keratoconus: Comparison of Dextran-Based and Hydroxypropyl Methylcellulose-Based Riboflavin Solutions Differences in demarcation line depth and 1 yaear outcomes." Revista de Chimie 70, no. 4 (2019): 1152–56. http://dx.doi.org/10.37358/rc.19.4.7083.

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Keratoconus is a progressive ectatic disorder characterised by irregular myopic astigmatism and loss of visual acuity due to corneal thinning. Corneal collagen crosslinking is the treatment recognised to stop the progression of keratoconus. Our study evaluates and compares visibility and depth of the stromal demarcation line after corneal collagen crosslinking using anterior segment optical coherence tomography between two groups:crosslinking with dextran-based and hydroxypropyl methylcellulose-based riboflavin solutions. Our work proved a better visibility and a deeper demarcation line when w

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Ilkhawati, Sukma Ayu, Endang Diyah Ikasari, and Erwin Indriyanti. "FORMULASI DAN OPTIMASI KADAR HYDROXYPROPYL METHYLCELLULOSE K100M DAN POLYVINYL ACETATE DALAM SEDIAAN PATCH TRANSDERMAL PROPRANOLOL HCl." Medical Sains : Jurnal Ilmiah Kefarmasian 8, no. 2 (2023): 405–14. http://dx.doi.org/10.37874/ms.v8i2.671.

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Propranolol hidroklorida merupakan penghambat reseptor beta-1 yang digunakan untukterapi angina, aritmia jantung, dan hipertensi. Penggunaannya secara oral memiliki beberapamasalah seperti mengalami first pass effect, indeks terapi sempit, dan rasa yang pahit.Kekurangan tersebut bisa diatasi dengan memformulasikannya sebagai sediaan transdermalberupa patch. Komponen yang digunakan dalam patch transdermal adalah kombinasipolimer hidrofilik yaitu HPMC K100M dan PVA. Optimasi dilakukan dengan SimplexLattice Design agar diperoleh formula optimal yang menghasilkan patch transdermalpropranolol HCl d

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Dezotti, Rafael S., Laíse M. Furtado, Márcio Yee, et al. "Tuning the Mechanical and Thermal Properties of Hydroxypropyl Methylcellulose Cryogels with the Aid of Surfactants." Gels 7, no. 3 (2021): 118. http://dx.doi.org/10.3390/gels7030118.

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The mechanical and thermal properties of cryogels depend on their microstructure. In this study, the microstructure of hydroxypropyl methylcellulose (HPMC) cryogels was modified by the addition of ionic (bis (2-ethylhexyl) sodium sulfosuccinate, AOT) and non-ionic (Kolliphor® EL) surfactants to the precursor hydrogels (30 g/L). The surfactant concentrations varied from 0.2 mmol/L to 3.0 mmol/L. All of the hydrogels presented viscous behavior (G″ > G′). Hydrogels containing AOT (c > 2.0 mmol/L) led to cryogels with the lowest compressive modulus (13 ± 1 kPa), the highest specific surface

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Yao, Risheng, Jiajia Xu, Xihua Lu, and Shengsong Deng. "Phase Transition Behavior of HPMC-AA and Preparation of HPMC-PAA Nanogels." Journal of Nanomaterials 2011 (2011): 1–6. http://dx.doi.org/10.1155/2011/507542.

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The lower critical solution temperature (LCST) of hydroxypropyl methylcellulose (HPMC) under mixing with acrylic acid (AA) monomer has been studied by turbidity measurements. It has been found that the LCST of the HPMC was drastically reduced from 60°C to 38°C with the increase of the concentration of AA, while the HPMC is kept at 0.5 wt%. The driving force shifting the LCST is attributed to the hydrogen bonding and hydrophobic interaction of the molecules. Then surfactant-free HPMC-PAA nanogels have been synthesized via the polymerization of AA monomer with the collapsed HPMC as a template or

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Wang, Xingyu, and Hong Sun. "Synergistic Effect of Microbial-Induced Carbonate Precipitation Modified with Hydroxypropyl Methylcellulose on Improving Loess Disintegration and Seepage Resistance." Polymers 17, no. 4 (2025): 548. https://doi.org/10.3390/polym17040548.

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Microbial-induced carbonate precipitation (MICP) is an eco-friendly soil stabilization technique. This study explores the synergistic effects of incorporating hydroxypropyl methylcellulose (HPMC) into the MICP process to enhance the disintegration and seepage resistance of loess. A series of disintegration, seepage, scanning electron microscopy (SEM), and mercury intrusion porosimetry (MIP) tests were conducted. The results show that HPMC forms protective membranes around calcium carbonate crystals produced by MICP and soil aggregates, which enhance cementation, reduce soluble salt dissolution

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Ong, Hsiao-Hui, YongChiat Wong, Jayant Khanolkar, et al. "Inhibitory Activity of Hydroxypropyl Methylcellulose on Rhinovirus and Influenza A Virus Infection of Human Nasal Epithelial Cells." Viruses 17, no. 3 (2025): 376. https://doi.org/10.3390/v17030376.

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The nasal epithelium is the primary site for entry of respiratory viruses. In comparison to oral administration, nasal drug applications directed locally to the site of infection can serve as early interventional barriers against respiratory virus pathogenesis by limiting viral spread in the upper airway. Experiments on the diffusion of methylene blue and nanoparticles in both water and low pH conditions revealed that hydroxypropyl methylcellulose (HPMC) can act as an effective physical barrier. This study also evaluated the activity of HPMC as a barrier against common respiratory viruses, i.e

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Genç, Lütfi, and A. Kıran. "In Vitro Evaluation of Sustained Released Matrix Tablet Formulations of Clarithromvcin." Scientia Pharmaceutica 73, no. 1 (2005): 59–74. http://dx.doi.org/10.3797/scipharm.aut-05-05.

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Sustained release matrix tablets of clarithromycin were prepared using different polymers as Hydroxypropyl methylcellulose (H PMC), Carbopol 934 and Eudragit RL/PO by direct compression technique. For the quality control of these formulations, weight deviation, hardness, friability, diameter-height ratio, content uniformity of the active substance and in vitro dissolution technique were performed. HPLC was used for the assay of clarithromycin and the assay method was validated. Dissolution profiles of the tablets were plotted and evaluated kinetically. The effects on drug release of polymer ty

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Krishnadev, Paladugu, Kizhaeral S. Subramanian, Arunachalam Lakshmanan, Shunmugam Ganapathy, Kalimuthu Raja, and Subramania Krishnaraj Rajkishore. "Hydroxypropyl methylcellulose nanocomposites containing nano fibrillated cellulose (NFC) from Agave americana L. for food packaging applications." BioResources 16, no. 4 (2021): 8125–51. http://dx.doi.org/10.15376/biores.16.4.8125-8151.

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Hydroxypropylmethylcellulose (HPMC) is popularly known as a hydrocolloid for potential use as a biopolymer film. The films of HPMC exhibit brittleness, lacking flexibility, but they can provide a gas barrier. With the aim of improving the HPMC film properties, nanofibrillated cellulose (NFC) from the succulent plant Agave americana L was incorporated as reinforcement material using the solution casting method. The films were prepared with three different amounts of NFC with glycerol as a plasticizer. The incorporation of the NFC into the nanocomposite films showed a 1,000-fold reduction in the

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