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Journal articles on the topic 'Hyperbaric vs'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Adi Praja Semara Putra, Komang. "Addition of Hyperbaric Oxygen Therapy vs Standard Therapy in SSNHL." KESANS : International Journal of Health and Science 1, no. 4 (2022): 391–95. http://dx.doi.org/10.54543/kesans.v1i4.49.

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The background of sudden sensorineural hearing loss is that occurs suddenly, with unknown causes, and the number of cases increases with age. The modality of therapy that is often used today is empiric therapy. The purpose of this literature review is to determine the impact of adding hyperbaric oxygen therapy compared to standard therapy in cases of sudden sensorineural hearing loss. Methods The article search was carried out in various valid online data centers, namely PubMed, Science Direct, Cochrane Library, and Google Scholar. Looking for articles that discuss the addition of hyperbaric o

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Cousin, Nicolas, Julien Goutay, Patrick Girardie, et al. "Effects of high oxygen tension on healthy volunteer microcirculation." Diving and Hyperbaric Medicine Journal 52, no. 4 (2022): 260–70. http://dx.doi.org/10.28920/dhm52.4.260-270.

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Introduction: Previous studies have highlighted hyperoxia-induced microcirculation modifications, but few have focused on hyperbaric oxygen (HBO) effects. Our primary objective was to explore hyperbaric hyperoxia effects on the microcirculation of healthy volunteers and investigate whether these modifications are adaptative or not. Methods: This single centre, open-label study included 15 healthy volunteers. Measurements were performed under five conditions: T0) baseline value (normobaric normoxia); T1) hyperbaric normoxia; T2) hyperbaric hyperoxia; T3) normobaric hyperoxia; T4) return to norm

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Fatima, Dr Homa, Dr Manish Kumar, Dr Ashutosh Jha, and Dr Md Arshad Imam. "A Comparative Study Of Intrathecal 0.5% Hyperbaric Bupivacaine And Intrathecal 0.75% Hyperbaric Ropivacaine In Lower Abdominal Surgeries." IOSR Journal of Dental and Medical Sciences 23, no. 11 (2024): 08–15. https://doi.org/10.9790/0853-2311090815.

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Background: Spinal anaesthesia has been widely used since its introduction in 1898 due to its safety and advantages over general anaesthesia. However, traditional agents like bupivacaine have some disadvantages, including cardiovascular effects and longer duration of action. Ropivacaine has emerged as a potential alternative with reduced cardiovascular toxicity. The study was aimed to compare the efficacy and suitability of 0.75% hyperbaric ropivacaine with 0.5% hyperbaric bupivacaine in patients undergoing lower limb and endoscopic urological surgeries, evaluating onset, quality, duration of

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Fultambkar, Gajanan, G. Nanda Kishore, V. Rajeswar Rao, David Raju, and Vinay Kukreja. "A Prospective Randomised Controlled Study Comparing the Efficacy of Hyperbaric Levo Bupivacaine with Nalbuphine Versus Hyperbaric Ropivacaine with Nalbuphine in Subarachnoid Block for Lower Limb Orthopaedic Surgeries." Asian Journal of Medicine and Health 23, no. 4 (2025): 133–42. https://doi.org/10.9734/ajmah/2025/v23i41214.

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Background: Spinal anaesthesia is the most preferred regional anesthesia technique as it is easy to perform, economical and produces rapid onset of anaesthesia and complete muscle relaxation. Present study aims to evaluate the effects of intrathecal 0.5% hyperbaric levobupivacaine combined with nalbuphine versus intrathecal 0.75% hyperbaric ropivacaine combined with nalbuphine, in patients undergoing Orthopedic surgeries of the lower limbs. Materials and Methods: A total of 60 patients, categorized into ASA grading I and II, were randomly allocated into Group LB and Group R of 30 each. Group L

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Pratiwi, A., M. Rum, A. S. Palinrungi, A. Salahuddin, F. Faisal, and H. Nurdin. "Prilocaine vs bupivacaine in spinal anesthesia for urologic endoscopy: clinical trials & historical overview." Messenger of ANESTHESIOLOGY AND RESUSCITATION 21, no. 4 (2024): 50–59. http://dx.doi.org/10.24884/2078-5658-2024-21-4-50-59.

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Introduction. In the evolving landscape of anesthetic practices for short-duration urologic procedures, the quest for an anesthetic agent that balances efficacy with minimal side effects remains a significant clinical challenge.The objective was to compare the efficacy and safety of 2% hyperbaric prilocaine and 0.5% hyperbaric bupivacaine in spinal anesthesia.Materials and methods. A comparative analysis was performed in terms of onset and duration of sensory and motor block, incidence of side effects (hypotension and bradycardia), and overall patient outcomes in urologic endoscopy. The resear

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Dr, P. Lekha Priyadharshini, and V. Jayaraman Dr. "Effects of low Doses of Intrathecal Clonidine and Dexmedetomidine with Bupivacaine on The Duration of Sensory and Motor Block in Abdominal and Lower Limb Surgeries- A Prospective Randomised Double Blinded Study." INTERNATIONAL JOURNAL OF HEALTH & MEDICAL RESEARCH 03, no. 05 (2024): 170–80. https://doi.org/10.5281/zenodo.11097651.

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BACKGROUND: The purpose of this study is to compare the duration of sensory and motor block in  elective lower limb and abdominal procedures following intrathecal administration of bupivacaine along with adjuvants either clonidine or dexmedetomidine.METHODS: A prospective randomised double blinded study. 120 study participants were randomly allocated to three groups-Group A was given 12.5 mg of hyperbaric bupivacaine, Group B was given 3 mcg dexmedetomidine along with 12.5 mg hyperbaric bupivacaine and Group C was given 30 mcg of clonidine along with hyperbaric bupivacaine. The duration o

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Chhanda CS, Rashid MSU, Mondal SK, et al. "Effectiveness of Consecutive Versus Premixed Administration of Fentanyl and Bupivacaine in Subarachnoid Block for Total Abdominal Hysterectomy." Journal of Sylhet Women’s Medical College 14, Number 1 (2024): 12–17. http://dx.doi.org/10.47648/jswmc2024v14-01-86.

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Background: Subarachnoid block (SAB) was a common regional anaesthetic technique, with opioids as adjuvants to enhance effectiveness and reduce hypotension. Objective: Comparison of the effectiveness of consecutive versus premixed administration of fentanyl and hyperbaric bupivacaine in subarachnoid block for TAH. Methods: This Quasi experimental study was carried out in 70 patients divided into two groups of 35 each: Group A received 0.5% hyperbaric bupivacaine 15mg (3ml) premixed with fentanyl 25µg (0.5ml) in a same syringe and Group Breceived fentanyl 25µg (0.5ml) in one syringe followed by

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Regmi, Bharati Devi Sharma, Gopendra Prasad Deo, Subin Shrestha, Sabita Shrestha, and Renuka Tamrakar Mishra. "LOW DOSE HYPERBARIC BUPIVACAINE WITH FENTANYL IN SPINAL ANESTHESIA IN ELECTIVE CESAREAN SECTION." Journal of Chitwan Medical College 9, no. 2 (2021): 79–82. http://dx.doi.org/10.54530/jcmc.375.

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Background: Spinal anesthesia with hyperbaric bupivacaine provides a dense neural block in cesarean delivery but associated with side effects like hypotension, bradycardia nausea and vomiting. Addition of low dose fentanyl with low dose of hyperbaric bupivacaine may decrease the incidence of these complications. The aims of study was to compare the hemodynamic parameters (blood pressure and heart rate), nausea and vomiting with low dose intrathecal hyperbaric bupivacaine with fentanyl vs a conventional dose of intrathecal hyperbaric bupivacaine in patient undergoing elective cesarean section.

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Regmi, Bharati Devi Sharma, Gopendra Prasad Deo, Subin Shrestha, Sabita Shrestha, and Renuka Tamrakar Mishra. "Low Dose Hyperbaric Bupivacaine with Fentanyl in Spinal Anesthesia in Elective Cesarean Section." Journal of Chitwan Medical College 9, no. 2 (2019): 79–82. http://dx.doi.org/10.3126/jcmc.v9i2.24560.

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Background: Spinal anesthesia with hyperbaric bupivacaine provides a dense neural block in cesarean delivery but associated with side effects like hypotension, bradycardia nausea and vomiting. Addition of low dose fentanyl with low dose of hyperbaric bupivacaine may decrease the incidence of these complications. The aims of study was to compare the hemodynamic parameters (blood pressure and heart rate), nausea and vomiting with low dose intrathecal hyperbaric bupivacaine with fentanyl vs a conventional dose of intrathecal hyperbaric bupivacaine in patient undergoing elective cesarean section.

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Kallio, H., M. Bachmann, P. Pere, P. Kairaluoma, and P. H. Rosenberg. "Hyperbaric vs. Plain Articaine for Spinal Anaesthesia." Regional Anesthesia and Pain Medicine 33, Sup 1 (2008): e8. http://dx.doi.org/10.1097/00115550-200809001-00014.

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Tantri, Aida Rosita, Juan Carson Roy Nathanael Marbun, and Aldy Heriwardito. "A randomized controlled trial comparing the recovery time after spinal anesthesia with 2% hyperbaric prilocaine 50 mg vs. 0.5% hyperbaric bupivacaine 12.5 mg for cystoscopic procedures." Anaesthesia, Pain & Intensive Care 27, no. 6 (2023): 689–96. http://dx.doi.org/10.35975/apic.v27i6.2145.

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Background: Cystoscopy is a urologic procedure performed as a diagnostic or a therapeutic intervention, usually requiring spinal anesthesia (SA). Bupivacaine is a frequently used spinal anesthesia agent. However, the prolonged duration of its effect is a disadvantage. Prilocaine may be an alternative for spinal anesthesia in cystoscopy, which has a shorter duration of action compared to bupivacaine. We compared recovery time of 2% hyperbaric prilocaine 50 mg vs. 0.5% hyperbaric bupivacaine 12.5 mg for cystoscopic procedures under spinal anesthesia. Methods: This study was a randomized co

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Pere, P., P. Kairaluoma, M. Bachmann, H. Kallio, and P. Rosenberg. "Intrathecal hyperbaric articaine vs. hyperbaric bupivacainefentanyl for day-case open inguinal hernia repair." European Journal of Anaesthesiology 27 (June 2010): 131. http://dx.doi.org/10.1097/00003643-201006121-00420.

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Hawley, D., M. J. Halsey, and B. Wardley-Smith. "Hyperbaric-induced subfertility in mice: lack of effect of decompression." Journal of Applied Physiology 60, no. 5 (1986): 1710–12. http://dx.doi.org/10.1152/jappl.1986.60.5.1710.

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Male mice were exposed to 50 atmospheres absolute (ATA). He for 30 min, twice weekly for 5 wk and their fertility assessed by subsequently mating with untreated virgin females. The exposure schedule was designed to provide compression and decompression times the same as previous positive studies of hyperbaric-induced subfertility but with much shorter periods at maximum pressure (30 min vs. 24 h). We postulated that, if subfertility were associated with exposure to pressure per se rather than with compression or decompression, then the present experiments would fail to produce a decrease in ma

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Pollock, Julia E., Joseph M. Neal, Carol A. Stephenson, and Carol E. Wiley. "Prospective Study of the Incidence of Transient Radicular Irritation in Patients Undergoing Spinal Anesthesia." Anesthesiology 84, no. 6 (1996): 1361–67. http://dx.doi.org/10.1097/00000542-199606000-00012.

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Background There is considerable controversy regarding the role of subarachnoid 5% hyperbaric lidocaine in the syndrome transient radicular irritation (TRI). This randomized, double-blinded, prospective study was designed to determine the incidence of TRI and identify factors possibly contributing to its development. Methods One hundred fifty-nine ASA physical status 1 or 2 patients undergoing outpatient knee arthroscopy or unilateral inguinal hernia repair were prospectively randomized to receive spinal anesthesia with 5% hyperbaric lidocaine with epinephrine (60 mg with 0.2 mg epinephrine fo

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Wundiawan, Kristian Felix, Putu Agus Surya Panji, Wayan Suranadi, et al. "Comparison of Hemodynamic Profiles and Onset and Offset of Motor and Sensory Blockade between 2% Hyperbaric Prilocaine and 0.5% Hyperbaric Bupivacaine for Spinal Anesthesia in Scheduled Cesarean Sections: A Double-Blind, Randomized Clinical Trial." Bali Journal of Anesthesiology 9, no. 1 (2025): 35–41. https://doi.org/10.4103/bjoa.bjoa_17_25.

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Abstract Background: Hyperbaric prilocaine is claimed to have a more stable hemodynamic profile with a faster onset and faster recovery or offset for both motor and sensory blockade than bupivacaine. The goal of this study was to compare the hemodynamic profile and onset and offset of motor and sensory blockade between hyperbaric prilocaine and hyperbaric bupivacaine for scheduled cesarean section. Materials and Methods: This research is an experimental study, a single-centered and double-blinded randomized clinical trial. The independent variable was the type of spinal anesthesia administered

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Kasza, T., P. Knapik, H. Misiolek, and D. Knapik. "Spinal anaesthesia using hyperbaric 0.75% ropivacaine vs hyperbaric 0.5% bupivacaine for elective caesarean section." European Journal of Anaesthesiology 23, Supplement 37 (2006): 178. http://dx.doi.org/10.1097/00003643-200606001-00639.

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Naresh, Kumar Tyagi, Ranawat Pinu, Muhammad Shaahid Shaik, and Mangal Hardika. "Comparative Study to Evaluate the Efficacy of Hyperbaric Levobupivacaine with Buprenorphine versus Hyperbaric Bupivacaine with Buprenorphine in Spinal Anestheisa for Lower Abdominal Surgeries." International Journal of Pharmaceutical and Clinical Research 15, no. 11 (2023): 1189–96. https://doi.org/10.5281/zenodo.11230747.

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Background: Spinal anesthesia is crucial for lower abdominal surgeries, offering reliable anesthesia and pain management. This study compares the efficacy of two intrathecal anesthesia combinations, hyperbaric levobupivacaine with buprenorphine and hyperbaric bupivacaine with buprenorphine, for lower abdominal surgeries. Methods: A double-blind, randomized controlled study included 160 ASA 1 and 2 patients aged 18-75. They were assigned to Group L (hyperbaric levobupivacaine + buprenorphine) or Group B (hyperbaric bupivacaine + buprenorphine). Parameters evaluated included onset time of sensor

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Basnet, Ujjwal. "A Comparative study of intrathecal hyperbaric Bupivacaine with or without Morphine for Post-Operative Analgesia in Hysterectomy." Nepal Journal of Obstetrics and Gynaecology 13, no. 1 (2018): 34–37. http://dx.doi.org/10.3126/njog.v13i1.21615.

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Aims: The aim of the study is to compare the effect of addition of morphine with bupivacaine and bupivacaine alone in intrathecal anesthesia for the quality and the duration of analgesia in hysterectomy.Methods: Prospective randomized analytical study was conducted in patients undergoing hysterectomy under spinal anesthesia over period of one year. Patients were randomized into two groups: hyperbaric bupivacaine (15mg) only or hyperbaric Bupivacaine (15mg) plus Morphine (0.2mg). The mean duration for the request of first analgesia in post-operative period, mean visual analogue scale (VAS) scor

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Jacobson, J. M., J. R. Michael, R. A. Meyers, M. B. Bradley, A. M. Sciuto, and G. H. Gurtner. "Hyperbaric oxygen toxicity: role of thromboxane." Journal of Applied Physiology 72, no. 2 (1992): 416–22. http://dx.doi.org/10.1152/jappl.1992.72.2.416.

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Exposing rabbits for 1 h to 100% O2 at 4 atm barometric pressure markedly increases the concentration of thromboxane B2 in alveolar lavage fluid [1,809 +/- 92 vs. 99 +/- 24 (SE) pg/ml, P less than 0.001], pulmonary arterial pressure (110 +/- 17 vs. 10 +/- 1 mmHg, P less than 0.001), lung weight gain (14.6 +/- 3.7 vs. 0.6 +/- 0.4 g/20 min, P less than 0.01), and transfer rates for aerosolized 99mTc-labeled diethylenetriamine pentaacetate (500 mol wt; 40 +/- 14 vs. 3 +/- 1 x 10(-3)/min, P less than 0.01) and fluorescein isothiocyanate-labeled dextran (7,000 mol wt; 10 +/- 3 vs. 1 +/- 1 x 10(-4)/

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Kallio, H., M. Bachmann, P. Pere, P. Kairaluoma, and P. H. Rosenberg. "96. Hyperbaric vs. Plain Articaine for Spinal Anaesthesia." Regional Anesthesia & Pain Medicine 33, Suppl 1 (2008): e8.1-e8. http://dx.doi.org/10.1136/rapm-00115550-200809001-00014.

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KALLIO, H., M. BACHMANN, P. PERE, P. KAIRALUOMA, and P. ROSENBERG. "96: Hyperbaric vs. Plain Articaine for Spinal Anaesthesia." Regional Anesthesia and Pain Medicine 33, no. 5 (2008): e8-e8. http://dx.doi.org/10.1016/j.rapm.2008.07.018.

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Baldim, Leticia Botigeli, Ricardo Nejo Jr, Maria Eliza Jordani Souza, et al. "Effect of hyperbaric oxygen therapy on liver function during intermittent ischemia." Acta Cirurgica Brasileira 28, suppl 1 (2013): 61–65. http://dx.doi.org/10.1590/s0102-86502013001300012.

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PURPOSE: To analyze the effects of hyperbaric oxygen therapy on liver function in rats previously subjected to ischemia and reperfusion. METHODS: A randomly distribution of 23 Wistar rats was conducted into three groups: SHAM, animals subjected to surgical stress without restricting blood flow by clamping the hepatic pedicle, IR, rats underwent hepatic vascular occlusion intermittently for two complete cycles of 15 minutes of ischemia followed by 5 min of reperfusion, IR / HBO, rats underwent hepatic pedicle clamping and thereafter exposed to hyperbaric oxygen pressure of 2 absolute atmosphere

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Leder Macek, Aleeza J., Ronald S. Wang, Justin Cottrell, et al. "Hyperbaric Oxygen Therapy for Sudden Sensorineural Hearing Loss – A Comorbidity Lens." Undersea and Hyperbaric Medicine 51, no. 4 (2024): 393–402. https://doi.org/10.22462/730.

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Leder Macek AJ, Wang RS, Cottrell J, Kay-Rivest E, McMenomey SO, Roland Jr. T, Ross FL. Hyperbaric Oxygen Therapy for Sudden Sensorineural Hearing Loss – A Comorbidity Lens. Undersea Hyperb Med. 2024 Fourth Quarter; 51(4):393-402. Objective: To determine the outcomes of patients receiving hyperbaric oxygen therapy for sudden sensorineural hearing loss and the impact of patient comorbidities on outcomes. Study Design: Retrospective chart review. Setting: Tertiary referral center. Methods: All patients over 18 diagnosed with sudden sensorineural hearing loss between 2018 and 2021 who were treate

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G. Patel, Mamta, Ashka V. Surve, Arun George, Mittal S. Patel, Urvisha A. Mendpara, and Kavan J. Patel. "COMPARISON OF BUPIVACAINE-DEXMEDETOMIDINE VS BUPIVACAINE-FENTANYL VS BUPIVACAINE -SALINE FOR UNILATERAL SPINAL ANAESTHESIA IN LOWER LIMB SURGERY." International Journal of Advanced Research 11, no. 05 (2023): 1599–607. http://dx.doi.org/10.21474/ijar01/17028.

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Introduction: Addition of adjuvants like Dexmedetomidine and Fentanyl to hyperbaric Bupivacaine has been proposed to improve the quality of spinal anaesthesia. Aims and Objectives: The aim of current study was to compare the effects of adding Dexmedetomidine, Fentanyl and saline to low dose hyperbaric Bupivacaine (1 ml, 0.5%) on the properties of unilateral spinal anaesthesia. Methods and Materials: 120 patients divided into three groups. The spinal anaesthetic agent in each of the three groups was 1 mL bupivacaine 0.5% (5 mg). In groups BD, BF and BS, 5mcg of Dexmedetomidine, 25mg of Fentanyl

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Gebhardt, Volker, Benedikt Beilstein, Alexander Herold, et al. "Spinal hyperbaric prilocaine vs. mepivacaine in perianal outpatient surgery." Open Medicine 9, no. 6 (2014): 754–61. http://dx.doi.org/10.2478/s11536-013-0336-5.

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Bitterman, Haim, Noemi Bitterman, Yehuda Melamed, and Leon Cohen. "Effects of hyperbaric oxygen in circulatory shock induced by splanchnic artery occlusion and reperfusion in rats." Canadian Journal of Physiology and Pharmacology 67, no. 9 (1989): 1033–37. http://dx.doi.org/10.1139/y89-163.

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We studied the effects of hyperbaric oxygen in a severe model of circulatory shock induced by occlusion and reperfusion of major splanchnic arteries (splanchnic artery occlusion (SAO) shock). Pentobarbital-anesthetized rats subjected to total occlusion of the superior mesenteric and the celiac arteries for 40 min developed a severe shock state, resulting in a uniformly fatal outcome after release of the occlusion. Exposure to hyperbaric oxygen at 2 ATA (atmosphere absolute) (1 ATA = 0.1 MPa) was initiated immediately after reperfusion. SAO shock rats exposed to hyperbaric oxygen maintained mea

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Shrestha, SK, B. Bhattarai, and R. Shah. "Comparative Study of Hyperbaric Bupivacaine Plus Ketamine Vs Bupivacaine Plus Fentanyl for Spinal Anaesthesia during Caeserean Section." Kathmandu University Medical Journal 11, no. 4 (2015): 287–91. http://dx.doi.org/10.3126/kumj.v11i4.12523.

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Background Spinal anesthesia is widely used for caesarean section due to its rapid onset, low failure rate, complete analgesia. Addition of intrathecal ketamine and opioids to local anaesthetics seems to improve the quality of block and prolong the duration of analgesia.Objectives The purpose of this study was to compare the effect of intrathecal ketamine mixed with hyperbaric bupivacaine to intrathecal fentanyl mixed with hyperbaric bupivacaine.Methods One hundred parturients ASA Grade I scheduled for elective or semiurgent caesarean section under spinal anaesthesia were randomly divided into

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Hemsinli, Dogus, Safiye Tuba Kaplan, Sahin Kaplan, and Furkan Yildirim. "Hyperbaric Oxygen Therapy in the Treatment of Fontaine Stage IV Thromboangiitis Obliterans." International Journal of Lower Extremity Wounds 15, no. 4 (2016): 366–70. http://dx.doi.org/10.1177/1534734616666866.

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Ischemic wounds unresponsive to standard treatment in thromboangiitis obliterans are associated with amputation, morbidity, and mortality. In this study, hyperbaric oxygen therapy was added to standard treatment of 36 patients with thromboangiitis obliterans with ischemic ulcerated wounds in the extremities. Full recovery was observed in 52.7% of cases (25% at discharge, 27.7% during follow-up). Resting pain after treatment decreased significantly compared to pretreatment levels based on visual analog scale scores (7.1 ± 1.7 vs 2.2 ± 3.0, P = .0001). Mean wound area also decreased significantl

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Pavlov-Dolijanovic, S., V. Koletic, N. Vujasinovic Stupar, and N. Damjanov. "AB0600 THE EFFECTS OF HYPERBARIC OXYGEN THERAPY TO QUALITY OF LIFE AND STATE OF MICROCIRCULATION IN PATIENTS WITH SYSTEMIC SCLEROSIS - A PILOT STUDY." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1596.2–1596. http://dx.doi.org/10.1136/annrheumdis-2020-eular.2610.

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Background:Many treatments have been tried in therapy systemic sclerosis (SSc) patients but use of hyperbaric oxygen therapy (HBOT) is very limited.Objectives:To assess the effects of HBOT to quality of life and state of microcirculation in SSc patients.Methods:18 female patients aged 29-68 years (mean 57 years) with limited SSc and digital or leg ulcers were included in this work. The HBOT protocol comprised 20 sessions 5 day/weekly, 60 min, 100% oxygen at 2.2 ATA. The treated patients were evaluated at baseline and after 20 HBOT sessions. Evaluation consisted of physical examination, capilla

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Kour, Loveleen, and Mushtaq Ahmed Wani. "Comparison of thoracic vs lumbar spinal anaesthesia fo orthopaedic surgeries." International Journal of Research in Medical Sciences 7, no. 6 (2019): 2323. http://dx.doi.org/10.18203/2320-6012.ijrms20192521.

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Background: Thoracic spinal anaesthesia has emerged as one of the most promising anaesthetic techniques in the recent times. On the other hand, lumbar approach has been the conventional choice for orthopaedic surgeries since the advent of spinal anaesthesia. This study aimed at determining which approach is better suited for orthopaedic surgeries.Methods: Total 60 patients scheduled for orthopaedic surgeries were divided into two groups : group T and group L. Group T patients were given thoracic spinal anaesthesia at the T9-T10 / T10-T11 interspace using 1.5 ml of hyperbaric bupivacaine 0.5% (

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Pratiwi, A., M. Rum, A. S. Palinrungi, A. Salahuddin, F. Faisal, and H. Nurdin. "Comparative Efficacy of 2% Hyperbaric Prilocaine vs 0.5% Hyperbaric Bupivacaine in Spinal Anesthesia for Urologic Endoscopy Procedures." Russian Journal of Pain 22, no. 3 (2024): 19. http://dx.doi.org/10.17116/pain20242203119.

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Azam, M., Itrat Hussain Kazmi, Naila Asad, et al. "Effect of Intrathecal Dexmedetomedine as Adjuvant to Bupivacaine in Caesarian Section: A Double Blind Study." Pakistan Journal of Medical and Health Sciences 16, no. 5 (2022): 34–36. http://dx.doi.org/10.53350/pjmhs2216534.

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Aim: To explore the impact of dexmedetomedine as adjuvant to hyperbaric bupivacaine 0.5% in spinal anaesthesia in caesarian section. Methods: This study was conducted in Services Hospital, Lahore from 23-2-21 to 31-05-21. Two groups of 30 each were made by dividing patients randomly. Group B was given hyperbaric bupivacaine 0.5% (10mg) diluted in normal saline and in Group BD dexmedetomedine 5µg (0.5 ml) was added to 10mg hyperbaric bupivacaine (0.5%). Spinal Anaesthesia was administered with 25G spinal needle. Haemodynamic changes, onset and duration of sensory and motor block were documented

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Zhu, Katherine J., Matthew J. Heron, Rafael Felix P. Tiongco, et al. "Hyperbaric Oxygen Therapy in Immediate Tissue Expander–Based Breast Reconstruction." Annals of Plastic Surgery 94, no. 4S (2025): S305—S310. https://doi.org/10.1097/sap.0000000000004321.

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Background Prepectoral tissue expander (TE) placement is an increasingly used breast reconstruction technique but may have a higher risk for mastectomy skin flap ischemia compared to subpectoral TE placement. Hyperbaric oxygen therapy (HBOT) has been shown to salvage compromised mastectomy skin flaps, but there is limited evidence on which patients require HBOT and benefit most from this treatment. Methods We retrospectively reviewed patients undergoing immediate TE breast reconstruction over a 6-year period. Patient demographics, intraoperative data, HBOT treatment, complications, and final b

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Van Herreweghe, Imré, Eline Ghysels, Jens Gielen, et al. "Baricity of spinal bupivacaine and the incidence of hypotension in non-obstetric surgery." European Journal of Anaesthesiology Intensive Care 4, no. 1 (2024): e0064. https://doi.org/10.1097/ea9.0000000000000064.

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Bupivacaine is commonly used for spinal anaesthesia. The baricity of bupivacaine (isobaric vs. hyperbaric) may influence the spread, level of the block and the subsequent haemodynamic effects of the spinal anaesthesia. This review considers the available literature on the effect of baricity on the haemodynamic sequelae of spinal anaesthesia with bupivacaine. A literature search was conducted of the MEDLINE and EMBASE databases up to February 2024, following PRISMA guidelines. Randomised controlled trials (RCTs) comparing isobaric and hyperbaric bupivacaine in non-obstetric surgeries were inclu

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Wilkinson, David C., Ian M. Chapman, and Leonie K. Heilbronn. "Hyperbaric oxygen but not hyperbaric air increases insulin sensitivity in men with type 2 diabetes mellitus." Diving and Hyperbaric Medicine Journal 50, no. 4 (2020): 386–90. http://dx.doi.org/10.28920/dhm50.4.386-390.

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(Wilkinson DC, Chapman IM, Heilbronn LK. Hyperbaric oxygen but not hyperbaric air increases insulin sensitivity in men with type 2 diabetes mellitus. Diving and Hyperbaric Medicine. 2020 December 20;50(4):386–390. doi: 10.28920/dhm50.4.386-390. PMID: 33325020.) Introduction: We have previously shown that hyperbaric oxygen treatment (HBOT) increased insulin sensitivity in men who were obese or overweight, both with and without type 2 diabetes. The aim of this study was to test whether this insulin-sensitising effect is seen in hyperbaric air (HA). Methods: Men with type 2 diabetes who were obes

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Sharma, Neha, and Chetan Shukla. "Comparison between intrathecal bupivacaine and combination of bupivacaine and midazolam for postoperative pain relief after infraumbilical elective surgeries." International Journal of Research in Medical Sciences 8, no. 11 (2020): 4031. http://dx.doi.org/10.18203/2320-6012.ijrms20204899.

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Background: Objective of the study was to identify the efficacy of midazolam as an adjuvant to intrathecal hyperbaric bupivacaine 0.5%, a prospective, randomized, double blind study was conducted to compare the onset, duration of sensory and motor block, postoperative analgesia, hemodynamic changes and complications.Methods: Sixty patients, ASA I/II, Age 18-60 year, scheduled for infraumbilical surgeries, were randomly allocated to group BNS(n=30) to receive intrathecally 2.5 ml of 0.5% hyperbaric bupivacaine with 0.4 ml normal saline; and group BM (n=30) to receive 2.5 ml of 0.5% hyperbaric b

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Dhara, M. Shah, Baria Sarala, K. Patel Heena, and Aterkar Vrushali. "Efficacy of Intrathecal Dexmedetomidine and Fentanyl as Adjuvants to Hyperbaric Bupivacaine in Spinal Anesthesia for Lower Limb Procedures." International Journal of Pharmaceutical and Clinical Research 16, no. 8 (2024): 1112–16. https://doi.org/10.5281/zenodo.13621397.

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<strong>Background and Aim: </strong>There are different adjuvants that are being utilised alongside local anaesthetics to extend the duration of pain relief during and after surgery. Dexmedetomidine, a highly selective α2 adrenergic agonist, is becoming increasingly popular as a new neuraxial adjuvant. For this study, we examined and assessed the impact of using dexmedetomidine and fentanyl alongside intrathecally administered hyperbaric bupivacaine during lower extremity surgeries performed under subarachnoid block anaesthesia. Our goal was to determine the most effective perioper

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Krstulović, Jure, Goran Augustin, Ivan Romić, Ante Tavra, Franko Batinović, and Zrinka Hrgović. "Hyperbaric Oxygen Therapy in the Treatment of Crohn’s Disease." Healthcare 13, no. 2 (2025): 128. https://doi.org/10.3390/healthcare13020128.

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Background/Objectives: Our study describes hyperbaric oxygen therapy (HBOT) as an additional therapy in the conservative treatment of Crohn’s disease (CD) and its benefit in the early postoperative period to prevent surgical complications and improve gastrointestinal motility. Methods: This retrospective study evaluated HBOT in patients hospitalized at the Clinical Hospital Center Split for complications of CD between 2015 and 2020. Patients (N = 61) aged 19 to 67 with perianal fistulas, abscesses, fistulas, obstruction, stenosis, or bleeding were included, excluding those with ulcerative coli

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Kamal, Geeta, Raman Piplani, Anju Gupta, and Nidhi Sehgal. "Clonidine as an adjuvant to bupivacaine in spinal anaesthesia for infra-umbilical surgeries in children: a prospective randomized, double-blind trial." Ghana Medical Journal 55, no. 2 (2021): 103–10. http://dx.doi.org/10.4314/gmj.v55i2.2.

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Objective: Spinal anaesthesia (SA) is a well-established technique for infra-umbilical surgeries but is underutilized in children. One important reason is the limited duration of action. Clonidine is a useful adjuvant in this regard but has not been studied in a dose of 1.5 μg/kg.Design: a prospective randomized study Setting: A single centre study conducted at a Super speciality paediatric tertiary care centre.Participants: Sixty children (5-12yrs) scheduled for lower abdominal surgery with duration <90min were included.Interventions: The participants were randomized into two groups

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Canarslan Demir, Kübra, Burak Turgut, Gözde B. Sariyerli Dursun, Fatma S. Konyalioğlu, and Taylan Zaman. "The role of hyperbaric oxygen treatment in the management of spondylodiscitis." Diving and Hyperbaric Medicine Journal 54, no. 3 (2024): 162–67. http://dx.doi.org/10.28920/dhm54.3.162-167.

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Introduction: This study analysed treatment outcomes in a patient cohort diagnosed with spondylodiscitis, who received adjunct hyperbaric oxygen treatment (HBOT) in addition to antibiotic therapy at our clinic. Important considerations included the timing of HBOT initiation on treatment success, and recurrence rates. Methods: We retrospectively reviewed the records of all patients diagnosed with spondylodiscitis who received HBOT at the Underwater and Hyperbaric Medicine Clinic in Gulhane Training and Research Hospital, between 1 November 2016 and 25 October 2022. The patients received HBOT at

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Tong, Doris, Jean Wong, Frances Chung, et al. "Prospective study on Incidence and Functional Impact of Transient Neurologic Symptoms Associated with 1%Versus 5% Hyperbaric Lidocaine in Short Urologic Procedures." Anesthesiology 98, no. 2 (2003): 485–94. http://dx.doi.org/10.1097/00000542-200302000-00030.

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Background The objectives of this study were to compare the incidence, onset, duration and pain scores of transient neurologic symptoms (TNS) with 1% versus 5% hyperbaric lidocaine in spinal anesthesia for short urological procedures in a large prospective study. This study would also evaluate patient satisfaction, and impact of TNS on functional recovery to assess the clinical significance of TNS. Methods This was a multicenter, double-blind, randomized controlled trial. Four hundred fifty-three patients undergoing short transurethral procedures were randomized to receive 1% or 5% hyperbaric

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Madhukant and Prasad Sudama. "Comparative Study to Evaluate the Clinical Efficacy and Safety of Isobaric Levobupivacaine vs. Hyperbaric Bupivacaine in lower Limb Orthopaedic Surgeries." International Journal of Pharmaceutical and Clinical Research 16, no. 5 (2024): 2819–22. https://doi.org/10.5281/zenodo.13823069.

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<strong>Background:</strong> Bupivacaine is a widely used local anesthetic in lower limb orthopaedic surgeries due to its long duration of action. However, its racemic mixture is associated with cardiotoxicity and central nervous system toxicity. Levobupivacaine, the S(−)-enantiomer of bupivacaine, was developed to mitigate these risks while maintaining efficacy. <strong>Aim:</strong> This study aims to compare the clinical efficacy and safety of isobaric levobupivacaine versus hyperbaric bupivacaine in patients undergoing lower limb orthopaedic surgeries. <strong>Met

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Hollis, N. "Hyperbaric vs. isobaric bupivacaine for spinal anaesthesia for elective caesarean section." Anaesthesia 73, no. 6 (2018): 790–91. http://dx.doi.org/10.1111/anae.14315.

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Richardson, M. G., H. V. Collins, and R. Wissler. "A890 Intrathecal Plain vs. Hyperbaric Bupivacaine with Morphine for Cesarean Section." Anesthesiology 87, Supplement (1997): 890A. http://dx.doi.org/10.1097/00000542-199709001-00890.

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Bayoumy, Ahmed B., Erwin Lammet van der Veen, and Jacob Alexander de Ru. "Hyperbaric Oxygen Therapy vs Medical Therapy for Sudden Sensorineural Hearing Loss." JAMA Otolaryngology–Head & Neck Surgery 145, no. 8 (2019): 699. http://dx.doi.org/10.1001/jamaoto.2019.0924.

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Arieli, R., P. Svidovsky, and A. Abramovich. "Decompression sickness in the rat following a dive on trimix: recompression therapy with oxygen vs. heliox and oxygen." Journal of Applied Physiology 102, no. 4 (2007): 1324–28. http://dx.doi.org/10.1152/japplphysiol.01195.2006.

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Trimix (a mixture of helium, nitrogen, and oxygen) has been used in deep diving to reduce the risk of high-pressure nervous syndrome during compression and the time required for decompression at the end of the dive. There is no specific recompression treatment for decompression sickness (DCS) resulting from trimix diving. Our purpose was to validate a rat model of DCS on decompression from a trimix dive and to compare recompression treatment with oxygen and heliox (helium-oxygen). Rats were exposed to trimix in a hyperbaric chamber and tested for DCS while walking in a rotating wheel. We first

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Mamun, Md Al, Md Rabiul Alam, Suraya Akter, and Mozibul Haque. "Role of Fentanyl With Bupivacaine During Spinal Anaesthesia for Caesarean Section in Reducing Hypotension." Journal of the Bangladesh Society of Anaesthesiologists 32, no. 1 (2019): 28–34. http://dx.doi.org/10.3329/jbsa.v32i1.66550.

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Background and Objectives: The hypotension following spinal anaesthesia is a common problem incaesarean section. The combination of reduced dose of local anaesthetics with intrathecal opioids makesit possible to achieve adequate spinal anaesthesia with minimum hypotension. We investigated whetherthis synergistic phenomenon could be used to provide less frequent hypotension while incurring adequatespinal anaesthesia for caesarean section. Methods: Sixty women scheduled for caesarean delivery (thirty in each group) were divided into twogroups of patients who received a spinal injection of either

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Shah, Asim abdul sami. "COMPARISON OF HYPERBARIC BUPIVACAINE AND FENTANYL MIXTURE AND HYPERBARIC BUPIVACAINE ALONE ON BLOOD PRESSURE AND HEART RATE AMONG PATIENTS UNDERGOING UNILATERAL SPINAL BLOCK FOR LOWER LIMB SURGERIES." Insights-Journal of Health and Rehabilitation 3, no. 3 (Health & Rehab) (2025): 84–89. https://doi.org/10.71000/ta5z4g31.

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Background: Unilateral spinal anesthesia is widely utilized in lower limb surgeries due to its ability to provide effective anesthesia with reduced hemodynamic instability. Combining hyperbaric bupivacaine with fentanyl has been proposed to enhance anesthetic efficacy while reducing adverse effects such as hypotension and bradycardia. Despite its documented benefits, limited research has explored the impact of this combination in the Pakistani population, where unique demographic and physiological characteristics may influence clinical outcomes. Objective: To compare the effects of hyperbaric

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Bhar, Debasish, Santanu Saha, Suman Chattopadhyay, Sagnik Datta, and Anusree Paul. "Comparison between intrathecal fentanyl and dexmedetomidine as an adjuvant to hyperbaric 0.5% levobupivacaine in subarachnoid block for cesarean section: A prospective study." Serbian Journal of Anesthesia and Intensive Therapy 47, no. 1-2 (2025): 23–30. https://doi.org/10.5937/sjait2502023s.

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The effect of dexmedetomidine and fentanyl as an adjuvant with hyperbaric levobupivacaine in cesarean section has not been evaluated adequately by researchers until now. The present study is designed to compare the effect of 5 mcg of dexmedetomidine and 25 mcg fentanyl when added to intrathecal 0.5% hyperbaric levobupivacaine for cesarean section. This randomized controlled trial was done with 105 parturient undergoing cesarean section under spinal anesthesia. Parturient were randomly divided into three groups. Group DL received 5 mcg of dexmedetomidine along with 1.8 ml of hyperbaric levobupi

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Hamieh, Batoul, Patrick Borel, Sana Raouche та ін. "Post-Harvest Atmospheric Pressure and Composition Modify the Concentration and Bioaccessibility of α- and β-Carotene in Carrots and Sweet Potatoes". Foods 12, № 23 (2023): 4262. http://dx.doi.org/10.3390/foods12234262.

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Provitamin A (proVA) carotenoid synthesis and degradation are strongly influenced by environmental factors, including during post-harvest storage. Hypobaric and hyperbaric storages increase the shelf-life of many crops, but their effects on proVA carotenoids are not known. Our aim was to investigate the effects of modifications of atmospheric pressure and composition on α- and β-carotene concentration and bioaccessibility during the post-harvest storage of carrots and sweet potatoes. Vegetables were stored for 11–14 days at 20 °C in the dark in chambers with modified pressure and O2 concentrat

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