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1

Dunford, C. "Hypergranulation tissue." Journal of Wound Care 8, no. 10 (1999): 506–7. http://dx.doi.org/10.12968/jowc.1999.8.10.26222.

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2

Mitchell, Aby, and Doris Llumigusin. "The assessment and management of hypergranulation." British Journal of Nursing 30, no. 5 (2021): S6—S10. http://dx.doi.org/10.12968/bjon.2021.30.5.s6.

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Wound healing follows a process of four distinct phases: haemostasis, inflammation, proliferation and maturation. Problems can arise in any of these phases, delaying the wound process. Hypergranulation (also known as overgranulation) during the proliferation phase occurs when granulation tissue over grows beyond the wound surface. Such wounds have a discoloured, raised or swollen appearance and bleed easily. The cause may be infection, the effects of friction on the wound area, nutritional deficit or stress. Treatments will depend on the cause. There is a lack of studies on treatments for hype
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3

Kim, Su Ho, Byung Gil Choi, Jung Suk Ok, Ho Jong Chun, and Hae Giu Lee. "Policresulen to treat hypergranulation tissue around drainage tubes." Journal of Wound Care 32, Sup12 (2023): S11—S14. http://dx.doi.org/10.12968/jowc.2023.32.sup12.s11.

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Objective: To evaluate the efficacy of policresulen for the treatment of hypergranulation. Method: This was a retrospective study of patients with percutaneous catheters. Inpatients from two hospitals and those from outpatient clinics were included. Approximately 2ml of 50% policresulen solution was applied to hypergranulation tissue, which was then immediately pressed with gauze for 1–3 minutes using light pressure. When haemostasis was achieved and the granulation tissue size decreased, the procedure was terminated. Results: A total of eight patients (four females and four males) were includ
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4

Rollins, H. "Hypergranulation tissue at gastrostomy sites." Journal of Wound Care 9, no. 3 (2000): 125–27. http://dx.doi.org/10.12968/jowc.2000.9.3.25964.

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5

Cahill, S., J. R. Cryer, S. J. Otter, and K. Ramesar. "An amelanotic malignant melanoma masquerading as hypergranulation tissue." Foot and Ankle Surgery 15, no. 3 (2009): 158–60. http://dx.doi.org/10.1016/j.fas.2008.11.006.

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6

Stevancevic, Milenko, Bojan Toholj, and Aleksandar Potkonjak. "Undesired reaction following intramuscular application of medicine: Case history." Veterinarski glasnik 64, no. 5-6 (2010): 429–36. http://dx.doi.org/10.2298/vetgl1006429s.

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The paper describes the therapy of a neck wound in a horse that occurred as a consequence of an inflammatory reaction to an administered medicine. During the clinical examination, we established that it was a neck wound that had occurred as a consequence of an inflammatory reaction on the spot where the medicine had been administered. There was an expressed fist-size tissue defect, with necrosis covering the skin, the subcutaneous tissue, the cutaneous muscle, and the neck musculature. The ventral part of the wound contained a pocket with exudate and hypergranulation. Therapy was based on asce
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7

Milne, Catherine T., and Lisa Q. Corbett. "TREATMENT OF HYPERGRANULATION TISSUE USING AN OCR/COLLAGEN DRESSING." Journal of Wound, Ostomy and Continence Nursing 30, no. 3 (2003): S7. http://dx.doi.org/10.1097/00152192-200305000-00028.

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8

Adam, R. A., E. Mayatepek, and H. Schroten. "P0762 CRYOTHERAPY ON COMPLICATING HYPERGRANULATION TISSUE IN PERCUTANEOUS GASTROSCOPIC ENTEROSTOMY." Journal of Pediatric Gastroenterology and Nutrition 39, Supplement 1 (2004): S346—S347. http://dx.doi.org/10.1097/00005176-200406001-00886.

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9

Weinblatt, Daniel, and Adib Chaaya. "Marked Percutaneous Endoscopic Gastrostomy-Related Hypergranulation Tissue in an Adult." ACG Case Reports Journal 9, no. 11 (2022): e00909. http://dx.doi.org/10.14309/crj.0000000000000909.

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10

Hawkins-Bradley, B. "Treatment of a nonhealing wound with hypergranulation tissue and rolled edges." Journal of WOCN 29, no. 6 (2002): 320–24. http://dx.doi.org/10.1067/mjw.2002.129929.

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11

Hawkins-Bradley, Beth, and Mary Walden. "Treatment of a Nonhealing Wound With Hypergranulation Tissue and Rolled Edges." Journal of Wound, Ostomy and Continence Nursing 29, no. 6 (2002): 320–24. http://dx.doi.org/10.1097/00152192-200211000-00011.

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12

Moio, Mariagrazia, Ilaria Mataro, Giuseppe Accardo, Luigi Canta, and Fabrizio Schonauer. "Treatment of hypergranulation tissue with intralesional injection of corticosteroids: Preliminary results." Journal of Plastic, Reconstructive & Aesthetic Surgery 67, no. 6 (2014): e167-e168. http://dx.doi.org/10.1016/j.bjps.2014.03.017.

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13

McShane, Diana B., and Jane S. Bellet. "Treatment of Hypergranulation Tissue with High Potency Topical Corticosteroids in Children." Pediatric Dermatology 29, no. 5 (2012): 675–78. http://dx.doi.org/10.1111/j.1525-1470.2012.01724.x.

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14

Wang, Steven Q. "Pulsed-Dye Laser Treatment of Nonhealing Chronic Ulcer With Hypergranulation Tissue." Archives of Dermatology 143, no. 6 (2007): 700. http://dx.doi.org/10.1001/archderm.143.6.700.

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15

Quelemente, Bruno Assis, Ana Beatriz Pinto da Sillva Morita, and Angelo Teixeira Balbi. "Utilização da solução hipertônica de cloreto de sódio em ferida hipergranulada." Revista de Enfermagem UFPE on line 3, no. 2 (2009): 317. http://dx.doi.org/10.5205/reuol.202-1995-3-ce.0302200916.

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ABSTRACTObjective: to verify the efficiency of hypertonic solution (NaCl/20%) on the hypergranulation due to the constant hypergranulating wound beds treated in venous ulcers in the daily clinic practice, which delays and disables cells epithelization. Methodology: clinical case study, performed in an outpatient’s clinic of Médio Vale do Paraíba, from February to March 2008. MCT, 60 years old, female, white skin, systematic arterial hypertension controlled, with wounds on the middle part and region of distal third of the left leg. Dressings were made with prior sterilization sores of sodium ch
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16

Kornhaber, Rachel, Marie Jaeger, Moti Harats, Uri Aviv, Amir Zerach, and Josef Haik. "Treatment of hypergranulation tissue in burn wounds with topical steroid dressings: a case series." International Medical Case Reports Journal Volume 9 (August 2016): 241–45. http://dx.doi.org/10.2147/imcrj.s113182.

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17

León, Astrid H., Ferdynand Hebal, Christine Stake, Kerry Baldwin, and Katherine A. Barsness. "Prevention of hypergranulation tissue after gastrostomy tube placement: A randomised controlled trial of hydrocolloid dressings." International Wound Journal 16, no. 1 (2018): 41–46. http://dx.doi.org/10.1111/iwj.12978.

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18

Stevens, Nicole M., Terry Shultz, Ryan L. Mizner, and Meryl Gersh. "Treatment in an Outpatient Setting for a Patient With an Infected, Surgical Wound With Hypergranulation Tissue." International Journal of Lower Extremity Wounds 8, no. 1 (2009): 37–44. http://dx.doi.org/10.1177/1534734608329684.

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19

Bilalov, I. V. "ЕXPERIENCE OF LONG-TERM APPLICATION OF PERCUTANEOUS ENDOSCOPIC MICROGASTROSTOMY AS A METHOD OF ENTERIAL AND THERAPEUTIC PROVISION OF PATIENTS". Surgical practice, № 1 (20 березня 2022): 22–26. http://dx.doi.org/10.38181/2223-2427-2022-1-22-26.

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Purpose. Analysis of surgical aspects of the experience of 13 years of percutaneous endoscopic microgastrostomy for enteral therapeutic provision of patients with parkinsonism.Methods. The 4-year follow-up group (2012-2021) included 20 patients aged 55 to 72 years with severe Parkinson's disease, mostly men. From 2008 to 2012, patients underwent microgastrostomy installation using a Frezenius kit. Levodopa carbidopa was injected into the jejunum through a micro-drainage gastrostomy.Results. During the 1st year of gastrostomy functioning, the following complications developed: gastric juice lea
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20

Madden, Katherine, Kapila V. Paghdal, and George Cohen. "Potassium Titanyl Phosphate 532-nm Laser for Treatment of a Chronic Nonhealing Exophytic Wound with Hypergranulation Tissue." Dermatologic Surgery 37, no. 5 (2011): 716–19. http://dx.doi.org/10.1111/j.1524-4725.2011.01976.x.

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21

Suranigi, Shishir Murugharaj, Manoj Joshi, Pascal Noel Deniese, Kanagasabai Rangasamy, Syed Najimudeen, and James J. Gnanadoss. "Chronic Osteomyelitis of Clavicle in a Neonate: Report of Morbid Complication of Adjoining MRSA Abscess." Case Reports in Pediatrics 2016 (2016): 1–3. http://dx.doi.org/10.1155/2016/3032518.

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Osteomyelitis of clavicle is rare in neonates. Acute osteomyelitis of clavicle accounts for less than 3% of all osteomyelitis cases. It may occur due to contiguous spread, due to hematogenous spread, or secondary to subclavian catheterization. Chronic osteomyelitis may occur as a complication of residual adjoining abscess due to methicillin resistant staphylococcus aureus (MRSA) sepsis. We report a newborn female with right shoulder abscess that developed chronic clavicular osteomyelitis in follow-up period after drainage. She required multiple drainage procedures and was later successfully ma
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22

Yuan, Lam Hui, Fatimah Mat Johar, and Wan Azman Wan Sulaiman. "‘Magic Cream’-All treats, no tricks. The use of topical steroids for the treatment of hypergranulation tissue in burn wounds: A retrospective review." Burns Open 6, no. 4 (2022): 187–91. http://dx.doi.org/10.1016/j.burnso.2022.10.001.

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23

Aziz, Adel, Maysa Shemmiyeva, Alan Pang, and Namratha Mohan. "801 Biodegradable Polyurethane Matrix (BPM) in Small Scale Reconstruction of Malignant Resections in Functional Areas." Journal of Burn Care & Research 46, Supplement_1 (2025): S255. https://doi.org/10.1093/jbcr/iraf019.332.

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Abstract Introduction Biodegradable Polyurethane Matrix (BPM) are temporary, biocompatible scaffolds that support tissue regeneration in surgical defects while reducing the need for permanent solutions. Spiradenomas, benign skin tumors from sweat gland cells, often require surgical removal, which can lead to scarring, particularly around joints like the ankle. Preliminary studies show BPMs may be effective in managing defects from malignant resections in critical areas, but their role in resection margins is still an emerging area needing further investigation. Methods This case report present
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24

Wojcik, Michal, Paulina Kazimierczak, Vladyslav Vivcharenko, Malgorzata Koziol, and Agata Przekora. "Effect of Vitamin C/Hydrocortisone Immobilization within Curdlan-Based Wound Dressings on In Vitro Cellular Response in Context of the Management of Chronic and Burn Wounds." International Journal of Molecular Sciences 22, no. 21 (2021): 11474. http://dx.doi.org/10.3390/ijms222111474.

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Bioactive dressings are usually produced using natural or synthetic polymers. Recently, special attention has been paid to β-glucans that act as immunomodulators and have pro-healing properties. The aim of this research was to use β-1,3-glucan (curdlan) as a base for the production of bioactive dressing materials (curdlan/agarose and curdlan/chitosan) that were additionally enriched with vitamin C and/or hydrocortisone to improve healing of chronic and burn wounds. The secondary goal of the study was to compressively evaluate biological properties of the biomaterials. In this work, it was show
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25

Aji, Maskhul, Naziyah Naziyah, and Rizki Hidayat. "Efektivitas Polyurethane Foam sebagai Primary Dressing terhadap Fase Proliferasi Proses Penyembuhan Luka pada Pasien Venous Leg Ulcer di Wocare." MAHESA : Malahayati Health Student Journal 4, no. 4 (2024): 1466–79. http://dx.doi.org/10.33024/mahesa.v4i4.14186.

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ABSTRACT Venous Leg Ulcer is an open skin wound that occurs in areas affected by venous hypertension in the legs. In the proliferative phase, there is granulation tissue which is rich in new blood vessels that have been produced. Wound care has used Modern Dressings such as Polyurethane Foam which plays a role in absorbing exudate fluid and controlling hypergranulation, as well as putting pressure on the wound. To determine the effectiveness of Polyurethane Foam as Primary Dressing in the proliferation phase of the wound healing process in Venous Leg Ulcer patients in Wocare. Quasi-experimenta
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26

Tainturier, Benoit, and Camille Benoit-Godet. "Les plaies chroniques chez le cheval." Le Nouveau Praticien Vétérinaire équine 13, no. 48 (2019): 7–12. http://dx.doi.org/10.1051/npvequi/48007.

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Les plaies chroniques sont fréquemment rencontrées chez le cheval, notamment lors de cicatrisation par seconde intention. Il est important d’identifier les facteurs responsables de la chronicité, si besoin à l’aide d’examens complémentaires tels que l’imagerie. Une infection bactérienne de la plaie doit toujours être suspectée lors de retard à la cicatrisation et il faut également rechercher la présence de corps étrangers ou de séquestres osseux. La localisation de la plaie (en partie distale des membres notamment), l’état général du cheval, des thérapeutiques inadaptées, ou le développement d
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27

Nakonechnyy, R. A., and A. Y. Nakonechnyi. "OPTIMIZATION OF SURGICAL WOUND CARE AFTER URETHROPLASTY IN CHILDREN WITH HYPOSPADIA." Novosti Khirurgii 30, no. 1 (2022): 46–53. http://dx.doi.org/10.18484/2305-0047.2022.1.46.

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Objectives. To develop optimal postoperative wound care tactics for boys with hypospadias. Methods. The patients (128) with hypospadias aged from 11 months to 7 years were examined. The main group A consisted of 83 (64.8%) patients in whom we used a special bandage. It includes layer by layer of soft polyamide net two-sided onlay coated with soft silicone and adhesive properties, abundantly treated with an antimicrobial ointment containing an osmotic agent, sterile absorbent wipes with non-woven material, a circularly applied elastic bandage and an adhesive plaster with porous non-woven materi
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Shaprynskyi, V. O., A. V. Verba, Yе V. Shaprynskyi, and E. M. Horoshun. "INTESTINAL STOMA: CAUSES OF FORMATION AND ITS COMPLICATIONS." Kharkiv Surgical School, no. 2 (June 20, 2022): 64–68. http://dx.doi.org/10.37699/2308-7005.2.2022.13.

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Abstract. Aim. The aim of our work was to analyze the causes of intestinal fistula formation in injuries and diseases of the abdominal cavity of different genesis and to identify the causes of complications in them.
 Materials and methods. The results of treatment of 88 patients who were treated at the Military Medical Clinical Center of the Central Region and the Military Medical Clinical Center of the Northern Region, who underwent surgery with formation of intestinal fistula for the period from 2015 to 2022, were studied. The reasons for surgery in 17 cases were combat trauma to the ab
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Shaprynskyi, V. O., A. V. Verba, Y. V. Shaprynskyi, and Y. M. Khoroshun. "THIN AND THICK BOWL STOMAS: ETIOLOGY AND TYPES OF COMPLICATIONS." Art of Medicine 22, no. 2 (2022): 109–12. http://dx.doi.org/10.21802/artm.2022.2.22.109.

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The eight-year armed conflict in eastern Ukraine, which escalated into a full-scale war over the russian invasion, has led to an increase in the number of wounded with injuries to the abdominal cavity, retroperitoneal space and pelvis. This has led to an increase in the number of patients with intestinal stoma.
 The aim of our research was to analyze the surgical interventions that result in the formation of intestinal fistula, as well as the types of complications from the stoma.
 Materials and methods. The results of treatment of 90 patients who were treated at the Military Medical
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30

Prado, Giselle, Anna Nichols, and Martin Zaiac. "Resolution of Post-Surgical Hypergranulation Tissue with Topical Aluminum Chloride." SKIN The Journal of Cutaneous Medicine 2, no. 5 (2018). http://dx.doi.org/10.25251/2.5.8.

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Hypergranulation is the extension of granulation tissue beyond the required amount to close a tissue defect. We report our experience using aluminum chloride to treat a series of two patients with hypergranulation tissue. Both patients had lengthy treatment courses after Mohs surgery with growth of hypergranulation tissue that resolved once aluminum chloride was placed on the wound. Aluminum chloride is a useful hemostatic agent frequently employed in dermatology. It is a readily available and low-cost option for management of hypergranulation after dermatologic procedures. Chronic wounds are
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31

Maynell, Kimberly, William West III, Jenna Marek, et al. "Utilization of Topical Polysporin and Triamcinolone for the Treatment of Hypergranulation Tissue." Journal of Burn Care & Research, January 2, 2024. http://dx.doi.org/10.1093/jbcr/irad205.

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Abstract Hypergranulation is the abnormal accumulation of granulation tissue in a wound and is commonly seen in burns. It impairs wound healing and can predispose patients to infection. There is no gold standard treatment for hypergranulation tissue, but some options include surgical debridement, chemical cautery with silver nitrate, and topical steroids. Silver nitrate treatment is painful and can lead to scarring, so topical steroid use is on the rise. A retrospective review, between January 1, 2017 and August 30, 2021, at a tertiary burn center was performed to analyze outcomes of hypergran
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32

Hurley, Margaret, Jennifer Scott, and Andrea L. Zaenglein. "Management of Hypergranulation Tissue: A Report of a Pediatric Case." Pediatric Dermatology, February 6, 2025. https://doi.org/10.1111/pde.15897.

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ABSTRACTHypergranulation tissue is the overgrowth of granulation tissue during the proliferative phase of wound healing. Treatment of hypergranulation tissue in the pediatric patient is focused on efficacious and comfortable options, of which topical steroids have been successfully used. This report discusses management of a large area of hypergranulation and concurrent infection on the scalp of a pediatric patient.
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English, Nathan Carl, and Gary Dos Passos. "Orthopaedic Wire Debridement: A Novel Surgical Technique for Hypergranulated Burn Wounds." World Journal of Surgery, September 14, 2023. http://dx.doi.org/10.1007/s00268-023-07147-6.

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AbstractThe burn wound healing process can be protracted due to various factors, including burn depth, infection and hypergranulation. Hypergranulation impedes epithelialisation macroscopically by preventing cellular migration across the wound bed and microscopically through cell-to-cell signal interferences. Debridement, which is the act of removing necrotic tissue, hypergranulation, slough and foreign debris from the wound in order to expose the underlying viable bed, can be achieved using various techniques. This aids with wound bed preparation to facilitate and expedite healing. In this ar
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34

Shoham, Yoram, Paul Comish, Rotem Tsur, et al. "Topical steroid use for suppression of hypergranulation in burns: Trends across the Atlantic." Journal of Burn Care & Research, October 30, 2024. http://dx.doi.org/10.1093/jbcr/irae191.

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Abstract Hypergranulated wounds from thermal injury remain a complex and debilitating problem for burn patients. Currently, there is no standard therapy to prevent or treat hypergranulation following burn injury. Many centers use topical corticosteroids; however, their use seems to be geographically dependent and controversial. The primary aim of this study was to quantify the current use of topical corticosteroids for post-burn hypergranulation in North America (NA) and Europe, while secondarily assessing for perceptions of safety and efficacy. We designed a survey that was distributed to the
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35

Adam, R. A., E. Mayatepek, and H. Schroten. "P0762 CRYOTHERAPY ON COMPLICATING HYPERGRANULATION TISSUE IN PERCUTANEOUS GASTROSCOPIC ENTEROSTOMY." Journal of Pediatric Gastroenterology and Nutrition 39, S1 (2004). http://dx.doi.org/10.1002/j.1536-4801.2004.tb13192.x.

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36

Shiba, Masato, Tomoaki Doi, Hideshi Okada, et al. "Hypergranulation over a meshed split-thickness skin graft, a complication of negative-pressure wound therapy: a case report." Journal of Medical Case Reports 16, no. 1 (2022). http://dx.doi.org/10.1186/s13256-022-03521-5.

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Abstract Background We present a case of a rare complication of negative-pressure wound therapy (NPWT) wherein there was fixation of a meshed split-thickness skin graft (STSG), suspected as a failure by hypergranulation. However, the meshed STSG was integrated within 5 days of NPWT cessation. Case presentation A 22-year-old Asian man sustained 25% total-body-surface-area flame burns. After multiple operations, an ulcer was present on the proximal left thigh. On day 37 after admission, the ulcer was debrided, and an 11/1000-inch (0.28 mm) skin graft was taken from the ipsilateral thigh and mesh
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Elena, Merlo González, and Martínez González Gema. "Hipergranulación en úlceras de miembros inferiores." Enfermería Dermatológica 14, no. 40 (2020). https://doi.org/10.5281/zenodo.4012085.

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<strong>Introducci&oacute;n:</strong> La cicatrizaci&oacute;n de una lesi&oacute;n puede verse dificultada por la aparici&oacute;n de tejido de hipergranulaci&oacute;n, que suele estar relacionado con un ambiente inflamatorio excesivo, una infecci&oacute;n o la malignizaci&oacute;n del tejido. Las opciones de tratamiento m&aacute;s destacadas son manejar el exudado, ejercer presi&oacute;n local, cauterizar con nitrato de plata y/o aplicar corticoide t&oacute;pico, pero falta evidencia cient&iacute;fica al respecto.&nbsp;<strong>Desarrollo del caso:</strong> Mujer de 73 a&ntilde;os diab&eacute;
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Margulies, Shae, Tyler Marion, and Sami K. Saikaly. "Use of Potent Topical Corticosteroids (TCS) for Hypergranulation Tissue (HGT) in Pediatric Patients." Cureus, August 23, 2022. http://dx.doi.org/10.7759/cureus.28304.

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39

"Use of vinegar (acetic acid) to promote wound healing complicated by hypergranulation tissue." Journal of the American Academy of Dermatology 60, no. 3 (2009): AB203. http://dx.doi.org/10.1016/j.jaad.2008.11.878.

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40

Martins, Russell Seth, Joanna Weber, Kostantinos Poulikidis, et al. "Gene expression profiles in COVID-19-associated tracheal stenosis indicate persistent anti-viral response and dysregulated retinol metabolism." BMC Research Notes 17, no. 1 (2024). http://dx.doi.org/10.1186/s13104-024-06775-y.

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Abstract Introduction Coronavirus disease 2019 (COVID-19)-associated tracheal stenosis (COATS) may occur as a result of prolonged intubation during COVID-19 infection. We aimed to investigate patterns of gene expression in the tracheal granulation tissue of patients with COATS, leverage gene expression data to identify dysregulated cellular pathways and processes, and discuss potential therapeutic options based on the identified gene expression profiles. Methods Adult patients (age ≥ 18 years) presenting to clinics for management of severe, recalcitrant COATS were included in this study. RNA s
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41

Saikaly, Sami K., Lara E. Saikaly, and Francisco A. Ramos‐Caro. "Treatment of postoperative hypergranulation tissue with topical corticosteroids: A case report and review of the literature." Dermatologic Therapy 34, no. 2 (2021). http://dx.doi.org/10.1111/dth.14836.

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42

Kahveci, Güldan, Ekmel Burak Özşenel, and Sema Basat. "Effect of video-based education on percutaneous endoscopic gastrostomy tube use duration: A case report." Clinical Science of Nutrition, March 11, 2024, 1–4. http://dx.doi.org/10.62210/clinscinutr.2024.77.

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Percutaneous endoscopic gastrostomy (PEG) is a safe, practical, and effective method for enteral nutrition. Minor and major complications may occur after the placement of a PEG tube. In the content of the education provided to caregivers, information should be given about the potential complications and the importance of communicating with the nutrition support team when these issues arise. In this case, we present a patient who was fed through a PEG tube and experienced infections and hypergranulation tissue processes during a thirty-seven-month follow-up, which included one tube replacement.
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J. Salgado, Christopher, Christopher J. Salgado, Faris Hawatmeh, Lalama Maria, and Genesis Navas. "Application of Amniotic Tissue Matrix to Surgically Excised Hidradenitis Suppurativa Wounds: A Retrospective Review." Surgical Case Reports, February 17, 2021, 1–6. http://dx.doi.org/10.31487/j.scr.2021.02.10.

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Background: Hidradenitis suppurativa is a painful and disfiguring disease, which requires surgical management in severe cases. Improvements in management are necessary to decrease disease morbidity and improve outcomes. Aim: To determine the efficacy of applying amniotic tissue matrix to surgically-excised hidradenitis suppurativa wounds. Materials &amp; Methods: A 5-year retrospective chart review of patients who underwent surgical treatment of perineal, perianal, and inguinal hidradenitis suppurativa at the University of Miami Hospital was completed. The study group consisted of 5 patients w
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Moody, Megan N., Jennifer M. Landau, Leonard H. Goldberg, Denise Marquez, and Irene J. Vergilis-Kalner. "595 nm long pulsed dye laser with a hydrocolloid dressing for the treatment of hypergranulation tissue on the scalp in postsurgical defects." Dermatology Online Journal 17, no. 7 (2011). http://dx.doi.org/10.5070/d38cn396s7.

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Filippo, Paula Alessandra Di, Luiza Maria Feitosa Ribeiro, Francielli Pereira Gobbi, et al. "Effects of pure and ozonated sunflower seed oil (Helianthus annuus) on hypergranulation tissue formation, infection and healing of equine lower limb wounds." Brazilian Journal of Veterinary Medicine 42, no. 1 (2020). http://dx.doi.org/10.29374/2527-2179.bjvm1115321.

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Hauschild, G., J. Hardes, M. Dudda, A. Streitbürger, and M. Wahrenburg. "Impact of topography and added TiN-coating on adult human dermal fibroblasts after seeding on titanium surface in-vitro." Journal of Biomaterials Applications, February 15, 2024. http://dx.doi.org/10.1177/08853282241233194.

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Complications of transcutaneous osseointegrated prosthetic systems (TOPS) focus on the metal-cutaneous interface at the stoma. Besides pain due to scare tissue as well as undefined neuropathic disorders, there is high evidence that the stoma presents the main risk causing hypergranulation and ascending infection. To restore the cutaneous barrier function in this functional area, soft-tissue on- or in-growth providing a vital and mechanically stable bio-artificial conjunction is considered a promising approach. In this study we assessed viability and proliferation of adult human dermal fibrobla
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Ghiani, Alessandro, Konstantinos Tsitouras, Joanna Paderewska, et al. "Tracheal stenosis in prolonged mechanically ventilated patients: prevalence, risk factors, and bronchoscopic management." BMC Pulmonary Medicine 22, no. 1 (2022). http://dx.doi.org/10.1186/s12890-022-01821-6.

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Abstract Background Various complications may arise from prolonged mechanical ventilation, but the risk of tracheal stenosis occurring late after translaryngeal intubation or tracheostomy is less common. This study aimed to determine the prevalence, type, risk factors, and management of tracheal stenoses in mechanically ventilated tracheotomized patients deemed ready for decannulation following prolonged weaning. Methods A retrospective observational study on 357 prolonged mechanically ventilated, tracheotomized patients admitted to a specialized weaning center over seven years. Flexible bronc
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Salehi, Omar, Wei-Lun Gao, Christian Kenfield, and Geoff Hebbard. "Roux-en-Y jejunostomy in gastroparesis: Insight into patient perspectives and outcomes." World Journal of Gastrointestinal Surgery 17, no. 3 (2025). https://doi.org/10.4240/wjgs.v17.i3.102543.

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BACKGROUND Gastroparesis is a chronic motility disorder characterized by delayed gastric emptying in the absence of mechanical obstruction. Patients with refractory gastroparesis often require enteral nutrition support, but traditional feeding methods such as nasojejunal tubes and percutaneous gastrojejunostomy tubes have significant limitations including frequent displacement, infection, and impact on quality of life. AIM To explore patients’ experience post insertion of laparoscopic Roux-en-Y jejunostomy in a cohort of eight adult patients with idiopathic gastroparesis. METHODS Eight patient
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Vaeth, Anna M., Grant G. Black, Nicholas A. Vernice, et al. "Soft-Tissue Contouring and Nerve Management During Lower-Limb Osseointegration Surgery." JBJS Essential Surgical Techniques 15, no. 2 (2025). https://doi.org/10.2106/jbjs.st.22.00074.

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Background: Osseointegration provides a direct prosthesis interface for lower-limb amputees, many of whom are poor candidates for traditional socket-suspended prostheses. These skeletally anchored implants eliminate the skin-prosthesis interface, reducing complications such as soft-tissue breakdown, ulceration, and pain 1 . Soft-tissue contouring and management of peripheral nerves are essential aspects of osseointegrated implantation surgery for both transfemoral and transtibial amputees. These techniques protect the bone-implant interface, prevent skin-implant friction, and reduce neuroma fo
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Frölke, Jan Paul M., Robin Atallah, and Ruud Leijendekkers. "Press-Fit Bone-Anchored Prosthesis for Individuals with Transtibial Amputation." JBJS Essential Surgical Techniques 14, no. 2 (2024). http://dx.doi.org/10.2106/jbjs.st.23.00006.

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Background: This video article describes the use of bone-anchored prostheses for patients with transtibial amputations, most often resulting from trauma, infection, or dysvascular disease. Large studies have shown that about half of all patients with a socket-suspended artificial limb experience limited mobility and limited prosthesis use because of socket-related problems. These problems occur at the socket-residual limb interface as a result of a painful and unstable connection, leading to an asymmetrical gait and subsequent pelvic and back pain. In almost all of these cases, a bone-anchored
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