Relevant bibliographies by topics / Hyperosmotic agent

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Hyperosmotic agent'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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Journal articles on the topic "Hyperosmotic agent"

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Constable, P. D., W. W. Muir, and P. F. Binkley. "Hypertonic saline is a negative inotropic agent in normovolumic dogs." American Journal of Physiology-Heart and Circulatory Physiology 267, no. 2 (1994): H667—H677. http://dx.doi.org/10.1152/ajpheart.1994.267.2.h667.

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The inotropic effects of hypertonic saline (HS) and hyperosmotic dextrose (HD; 2,400 mosmol/l, 4 ml/kg) were determined in normovolumic, chloralose-anesthetized, intact (n = 14) and autonomically blocked (n = 8) dogs. Solutions were infused intravenously over 3 min. HS and HD rapidly increased preload in both intact and autonomically blocked dogs, as assessed by significant (P < 0.05) increases in plasma volume, end-diastolic volume, and end-diastolic pressure. In intact dogs, HS produced a nonsignificant decrease in end-systolic elastance (Ees) and a nonsignificant increase in the maximal rate of change of left ventricular pressure (dP/dtmax) and cardiac output, whereas HD produced a significant increase in Ees, dP/dtmax, and cardiac output. In autonomically blocked dogs, HS significantly decreased Ees and significantly increased dP/dtmax but did not alter cardiac output, whereas HD significantly increased Ees, dP/dtmax, and cardiac output. We conclude that in normovolumic animals, HS is a negative inotropic agent, HD is a positive inotropic agent, and the in vivo effect of an ionic hyperosmotic agent (HS) differs from that of a nonionic hyperosmotic agent (HD).
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Ghosn, Mohamad G., Esteban F. Carbajal, Natasha A. Befrui, Armando Tellez, Juan F. Granada, and Kirill V. Larin. "Permeability of hyperosmotic agent in normal and atherosclerotic vascular tissues." Journal of Biomedical Optics 13, no. 1 (2008): 010505. http://dx.doi.org/10.1117/1.2870153.

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Linville, Raleigh M., Jackson G. DeStefano, Matt B. Sklar, Chengyan Chu, Piotr Walczak, and Peter C. Searson. "Modeling hyperosmotic blood–brain barrier opening within human tissue-engineered in vitro brain microvessels." Journal of Cerebral Blood Flow & Metabolism 40, no. 7 (2019): 1517–32. http://dx.doi.org/10.1177/0271678x19867980.

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As the majority of therapeutic agents do not cross the blood–brain barrier (BBB), transient BBB opening (BBBO) is one strategy to enable delivery into the brain for effective treatment of CNS disease. Intra-arterial infusion of the hyperosmotic agent mannitol reversibly opens the BBB; however, widespread clinical use has been limited due to the variability in outcomes. The current model for mannitol-induced BBBO assumes a transient but homogeneous increase in permeability; however, the details are poorly understood. To elucidate the mechanism of hyperosmotic opening at the cellular level, we developed a tissue-engineered microvessel model using stem cell-derived human brain microvascular endothelial cells (BMECs) perturbed with clinically relevant mannitol doses. This model recapitulates physiological shear stress, barrier function, microvessel geometry, and cell-matrix interactions. Using live-cell imaging, we show that mannitol results in dose-dependent and spatially heterogeneous increases in paracellular permeability through the formation of transient focal leaks. Additionally, we find that the degree of BBB opening and subsequent recovery is modulated by treatment with basic fibroblast growth factor. These results show that tissue-engineered BBB models can provide insight into the mechanisms of BBBO and hence improve the reproducibility of hyperosmotic therapies for treatment of CNS disease.
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Holzman, Andrew, and Lorena LoVerde. "Effect of a hyperosmotic agent on epithelial disruptions during laser in situ keratomileusis." Journal of Cataract & Refractive Surgery 41, no. 5 (2015): 1044–49. http://dx.doi.org/10.1016/j.jcrs.2014.07.042.

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Tuchina, Daria K., Alexey N. Bashkatov, Elina A. Genina, and Valery V. Tuchin. "Quantification of glucose and glycerol diffusion in myocardium." Journal of Innovative Optical Health Sciences 08, no. 03 (2015): 1541006. http://dx.doi.org/10.1142/s1793545815410060.

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The results on determination of glucose and glycerol diffusion coefficients in myocardium tissue are presented. The method is based on the measurement and analysis of temporal dependence of tissue optical collimated transmittance under action of a hyperosmotic agent. This temporal tissue response is related to the rate of the agent and water diffusion in a tissue. The diffusion coefficients for tissue fluid fluxes at glucose and glycerol application to the myocardium at 20°C have been estimated as (4.75 ± 3.40) × 10-7 and (7.71 ± 4.63) × 10-7 cm2/s, respectively.
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Zeiler, F. A., L. M. Gillman, J. Teitelbaum, and M. West. "Early Implementation of THAM for ICP Control: Therapeutic Hypothermia Avoidance and Reduction in Hypertonics/Hyperosmotics." Case Reports in Critical Care 2014 (2014): 1–4. http://dx.doi.org/10.1155/2014/139342.

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Background. Tromethamine (THAM) has been demonstrated to reduce intracranial pressure (ICP). Early consideration for THAM may reduce the need for other measures for ICP control.Objective. To describe 4 cases of early THAM therapy for ICP control and highlight the potential to avoid TH and paralytics and achieve reduction in sedation and hypertonic/hyperosmotic agent requirements.Methods. We reviewed the charts of 4 patients treated with early THAM for ICP control.Results. We identified 2 patients with aneurysmal subarachnoid hemorrhage (SAH) and 2 with traumatic brain injury (TBI) receiving early THAM for ICP control. The mean time to initiation of THAM therapy was 1.8 days, with a mean duration of 5.3 days. In all patients, after 6 to 12 hours of THAM administration, ICP stability was achieved, with reduction in requirements for hypertonic saline and hyperosmotic agents. There was a relative reduction in mean hourly hypertonic saline requirements of 89.1%, 96.1%, 82.4%, and 97.0% for cases 1, 2, 3, and 4, respectively, comparing pre- to post-THAM administration. Mannitol, therapeutic hypothermia, and paralytics were avoided in all patients.Conclusions. Early administration of THAM for ICP control could potentially lead to the avoidance of other ICP directed therapies. Prospective studies of early THAM administration are warranted.
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Vargas, Gracie, Jennifer K. Barton, and Ashley J. Welch. "Use of hyperosmotic chemical agent to improve the laser treatment of cutaneous vascular lesions." Journal of Biomedical Optics 13, no. 2 (2008): 021114. http://dx.doi.org/10.1117/1.2907327.

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Ikeda, N. "Unilateral Symptomatic Elevation of Intraocular Pressure and Prevention Using a Hyperosmotic Agent During Hemodialysis." Japanese Journal of Ophthalmology 45, no. 6 (2001): 659–61. http://dx.doi.org/10.1016/s0021-5155(01)00408-7.

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Santi, P. A., B. N. Lakhani, L. B. Edwards, and T. Morizono. "Cell volume density alterations within the stria vascularis after administration of a hyperosmotic agent." Hearing Research 18, no. 3 (1985): 283–90. http://dx.doi.org/10.1016/0378-5955(85)90045-0.

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Zaman, Raiyan T., Narasimhan Rajaram, Brandon S. Nichols, et al. "Changes in morphology and optical properties of sclera and choroidal layers due to hyperosmotic agent." Journal of Biomedical Optics 16, no. 7 (2011): 077008. http://dx.doi.org/10.1117/1.3599985.

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Dissertations / Theses on the topic "Hyperosmotic agent"

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Zaman, Raiyan Tripti. "Efficacy of hyper-osmotic agent (100% anhydrous glycerol) in tissue and light-activated micro-pattern drug delivery device in in vivo rabbit eye." Thesis, 2011. http://hdl.handle.net/2152/ETD-UT-2011-05-2657.

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My PhD research involves multi-disciplinary areas of study such as measuring perfusion of blood vessels in hamster dorsal skin using laser speckle imaging technique. In this study the changes were measured in blood flow velocity and diameters of micro vasculatures after the influence of glycerol application. The second study identifies the changes in morphology and optical properties of eye tissue after applying hyper-osmotic agent such as 100% anhydrous glycerol. Further investigation on the reversal process was performed without any application of 0.9% saline. The third study identified the variation in fluorescence in hamster dorsal skin tissue and enucleated porcine eyes with temperature. This study investigated the variation in fluorescence intensity with temperatures starting at 14°C and compared in vivo and in vitro results for consistency. The fourth study investigated an implantable drug delivery package that was fabricated using PMMA and implanted between the sub-conjunctival and super-scleral space and release the content of the device by either mechanical pressure or light-activated ophthalmic Nd:YAG laser after optically clearing the eye tissue by topical application of a hyper-osmotic agent, 100% anhydrous glycerol. A hyper-osmotic agent creates a transport region in the conjunctiva and sclera to get visual access of the compartments in the drug delivery package. This new technology would provide the option to the patient of one time implantation of the carrier system containing the drug. Each time the patient requires medication a ND-YAG or other laser beam will propagate through the cleared eye tissue to release the drug in measurable doses at the discretion of the doctor from the package directly in to the vitreous humor. In this study we have measured half-life of the dye in the vitreous humor or posterior chamber and biocompatibility. The last study had drawn distinction between the fluorescence signals based on the location (anterior or posterior chamber) of the 10% Na fluorescence dye in the in vivo rabbit and ex vivo pig eyes.<br>text
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Rylander, Christopher Grady. "Measurement of transient transport of hyperosmotic agents across cell membranes and resulting optical clearing using differential phase contrast optical coherence microscopy." Thesis, 2005. http://hdl.handle.net/2152/2297.

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Book chapters on the topic "Hyperosmotic agent"

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Niiro, M., T. Asakura, K. Yatsushiro, M. Sasahira, K. Terada, and T. Fujimoto. "Magnetic Resonance Studies in Human Brain Oedema Following Administration of Hyperosmotic Agents." In Brain Edema VIII. Springer Vienna, 1990. http://dx.doi.org/10.1007/978-3-7091-9115-6_44.

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Stamper, Robert L., Marc F. Lieberman, and Michael V. Drake. "Hyperosmotic agents." In Becker-Shaffer's Diagnosis and Therapy of the Glaucomas. Elsevier, 2009. http://dx.doi.org/10.1016/b978-0-323-02394-8.00028-0.

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"Hyperosmotic agents." In Ophthalmology for Lawyers. Routledge-Cavendish, 1997. http://dx.doi.org/10.4324/9781843143666-32.

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Garg, Ashok. "Topical Hyperosmotic Agents." In Ocular Therapeutics. Jaypee Brothers Medical Publishers (P) Ltd., 2013. http://dx.doi.org/10.5005/jp/books/11828_19.

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"Chapter 37 Hyperosmotic Agents." In Glaucoma, edited by John C. Morrison and Irvin P. Pollack. Georg Thieme Verlag, 2003. http://dx.doi.org/10.1055/b-0034-50801.

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Athiya, Agarwal. "Chapter-246 Topical Hyperosmotic Agents." In Textbook of Ophthalmology (Vol 1)-Amar Agarwal. Jaypee Brothers Medical Publishers (P) Ltd., 2002. http://dx.doi.org/10.5005/jp/books/10931_246.

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Conference papers on the topic "Hyperosmotic agent"

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Zaman, Raiyan T., Henry G. Rylander III, Narasimhan Rajaram, et al. "Changes in morphology and optical properties of sclera due to hyperosmotic agent." In SPIE BiOS: Biomedical Optics, edited by Steven L. Jacques, E. Duco Jansen, and William P. Roach. SPIE, 2009. http://dx.doi.org/10.1117/12.809701.

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Xiong, Honglian, Zhouyi Guo, Changchun Zeng, Like Wang, Yonghong He, and Songhao Liu. "Nondestructive quantification of permeability of hyperosmotic agent in normal and tumor tissues." In Photonics and Optoelectronics Meetings, edited by Qingming Luo, Lihong V. Wang, and Valery V. Tuchin. SPIE, 2008. http://dx.doi.org/10.1117/12.821348.

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Musina, Guzel, Nikita Chernomyrdin, Arsenii Gavdush, et al. "Selection of optimal hyperosmotic agent for tissue immersion optical clearing in the terahertz range." In Optical Interactions with Tissue and Cells XXXII, edited by Bennett L. Ibey and Norbert Linz. SPIE, 2021. http://dx.doi.org/10.1117/12.2576895.

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Yoon, Jinhee, Taeyoon Son, and Byungjo Jung. "Quantitative analysis method to evaluate optical clearing effect of skin using a hyperosmotic chemical agent." In 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2007. http://dx.doi.org/10.1109/iembs.2007.4353047.

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Drew, Chris W., and Christopher G. Rylander. "Mechanical Compression for Dehydration and Optical Clearing of Skin." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-193017.

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The highly disordered refractive index distribution in biological tissue causes multiple-scattering of incident light and inhibits optical penetration depth. “Tissue optical clearing” increases penetration depth of near-collimated light in biological tissue, potentially resulting in improved optical analysis and treatment techniques. Numerous methods of tissue optical clearing have been hypothesized using hyperosmostic agents [1]. These methods propose reduction in light scattering by means of dehydration of tissue constituents, replacement of interstitial or intracellular water with higher refractive agents, or structural modification or dissociation of collagen fibers [2,3]. It has been suggested that dehydration of tissue constituents alone can reduce light scattering by expulsing water between collagen fibrils, increasing protein and sugar concentrations, and decreasing refractive index mismatch [4].
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Jiang, Jingying, Ruikang K. Wang, and Kexin Xu. "Controlling optical properties of biotissue by the use of biocompatible hyperosmotic agents." In Biomedical Optics (BiOS) 2007, edited by Sean J. Kirkpatrick and Ruikang K. Wang. SPIE, 2007. http://dx.doi.org/10.1117/12.700585.

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Drew, Chris W., Alondra Izquierdo-Roman, Yajing Liu, and Christopher G. Rylander. "Increased Light Transport in Skin Using Mechanical Compression." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206628.

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The complex morphological structure of skin with its variations in the indices of refraction of components therein provides a highly scattering medium for visible and near-infrared wavelengths of light. “Tissue optical clearing” increases transmission of near-collimated light in biological tissue, potentially enabling improved optical analysis and treatment techniques. Numerous methods of tissue optical clearing have been hypothesized using hyperosmostic agents [1]. These methods propose reduction in light scattering by means of dehydration of tissue constituents, replacement of interstitial or intracellular water with higher refractive agents, or structural modification or dissociation of collagen fibers [2]. It has been suggested that dehydration of tissue constituents alone can reduce light scattering by expulsing water between collagen fibrils, increasing protein and sugar concentrations, and decreasing refractive index mismatch [3].
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Smolyanskaya, O. A., I. J. Schelkanova, E. L. Odlyanitskiy, et al. "Controlling penetration depth of the THz radiation in biological tissues by hyperosmotic agents." In 2017 42nd International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz). IEEE, 2017. http://dx.doi.org/10.1109/irmmw-thz.2017.8067199.

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Musina, Guzel R., Nikita V. Chernomyrdin, Arsenii A. Gavdush, Irina N. Dolganova, Valery V. Tuchin, and Kirill I. Zaytsev. "Selection of hyperosmotic agents for optical clearing of biological tissues in terahertz frequency range." In Terahertz Emitters, Receivers, and Applications XI, edited by Manijeh Razeghi and Alexei N. Baranov. SPIE, 2020. http://dx.doi.org/10.1117/12.2567538.

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Cicchi, R., D. Massi, D. Stambouli, D. D. Sampson, and F. S. Pavone. "Contrast enhancement in combined two-photon second harmonic imaging of skin by using hyperosmotic agents." In Biomedical Optics 2006, edited by Ammasi Periasamy and Peter T. C. So. SPIE, 2006. http://dx.doi.org/10.1117/12.644193.

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