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1

Strakhovetska, Yuliya. "Features of pathogeny of hyperplastic processes of uterus." Perinatology and reproductology: from research to practice 4, no. 2 (2024): 89–94. https://doi.org/10.52705/2788-6190-2024-02-14.

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The objective:establishment of role infectious to the pathogen in development of hyperplastic processes of uterus. Materials and methods. 250 women which were up-diffused on five groups were inspected. Plugging criteria are in research: presence of the combined hyperplastic processes of uterus - two and more for a disease (endometrial hyperplasia, uterine fibroids and adenomyosis), verified morphologically, fertile age (25–45 years). On the basis of clinical motion of disease, information of genital status and pathomorphological conclusion the followings groups were formed: I a group was made
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2

Sadygov, Yu M. "Actual aspects of clinical-anamnestic data of women of perimenopause age with hyperplastic processes an endometrium." HEALTH OF WOMAN, no. 8(144) (October 31, 2019): 72–74. http://dx.doi.org/10.15574/hw.2019.144.72.

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The objective: studying of clinical-anamnestic features of hyperplastic processes an endometrium at women of perimenopause age. Materials and methods. 100 women with hyperplastic processes an endometrium during the period perimenopause (the main group) were surveyed. As selection criterion of patients and their distributions on subgroups the morphological form of hyperplastic process an endometriya served. Among the patients surveyed at 54% the glandular hyperplasia an endometrium, was diagnosed for 24% – polyps an endometrium, for 22% – an adenomatous hyperplasia an endometrium. The control g
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3

Tsubanova, N. A., A. V. Barskaya, and T. D. Gubchenko. "Endometrium Hyperplastic Processes. Correction resources of naturopathic preparations." HEALTH OF WOMAN, no. 4(120) (May 30, 2017): 47–52. http://dx.doi.org/10.15574/hw.2017.120.47.

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The article presents modern aspects of etiopathogenetic factors of endometrium hyperplastic processes. Modern data on the classification, diagnosis and therapy of endometrial hyperplasia was analyzed. The possibility of using modern naturopathic drugs «Normomens» on the basis of extracts of Vitex agnus castus, Zingiber officinale, Trigonella foenum graecum, Pyrus malus and «Normocycle» containing extracts of Symplocos racemosa, Asparagus racemosus, Glycyrrhiza glabra, Curcuma longa was theoretically substantiated in the therapy of endometrium hyperplastic processes. Key words: endometrium hype
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4

Sadigov, Yu M. "Clinical-anamnestical features hyperplastic processes an endometrium at women of genesial age." HEALTH OF WOMAN, no. 6(132) (July 30, 2018): 92–95. http://dx.doi.org/10.15574/hw.2018.132.92.

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The objective: studying of clinical-anamnestic features the hyperplastic processes an endometrium at women of genesial age. Materials and methods. Clinical examination of 176 women with various options of hyperplastic processes an endometrium (the main group) and 30 women of similar age without gynecologic pathology was conducted. Among women of the main group glandular hyperplasia the endometriya met at 58 (33.0%) patients; polyps an endometrium – at 70 (39.8%) and adenomatous hyperplasia an endometrium – respectively at 48 (27.3%) women. Results. The conducted research taped that for the wom
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5

Strakhovetska, Yuliya. "Mikrobiologichni of feature of pathogenesis of hyperplastic processes of uterus." Perinatology and reproductology: from research to practice 4, no. 3-2 (2024): 63–68. https://doi.org/10.52705/2788-6190-2024-03.2-09.

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The objective: establishment of role infectious to the pathogen in development of hyperplastic processes of uterus. Materials and methods. 250 women which were up-diffused on five groups were inspected. Plugging criteria are in research: presence of the combined hyperplastic processes of uterus – two and more for a disease (hyperplasia of endometrium, uterine fibroids and adenomiosis), verified morphologically, of fertile age (25–45 years).On the basis of clinical motion of disease, information of genital status and pathomorphological conclusion the followings groups were formed: I a group was
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6

Tsyndrenko, Nataliia L., Anatolii M. Romaniuk, and Yana R. Nikolayenko. "CLINICAL, MORPHOLOGICAL, AND EPIDEMIOLOGICAL CHARACTERISTICS OF ENDOMETRIAL HYPERPLASTIC PROCESSES IN SUMY REGION." Eastern Ukrainian Medical Journal 9, no. 4 (2021): 342–51. http://dx.doi.org/10.21272/eumj.2021;9(4):342-351.

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Endometrial hyperplastic processes take an important place among the gynecological diseases in women of various ages and are one of the most common reasons for admission at inpatient gynecology departments. The urgency of the pathology is due to the significant prevalence of endometrial hyperplastic processes, high incidence of malignancy, prolonged relapsing course, and decreased reproductive function, since these diseases are one of the most common causes of infertility in women of childbearing age. The statistics related to the incidence of endometrial hyperplastic processes in Ukraine is n
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7

Krut, Yuri, Nataly Zemlyana, Natalie Gaidai, Mykhailo Pavliuchenko, and Iryna Amro. "The proliferation markers in patients with different forms of hyperplastic endometrial processes." Journal of Education, Health and Sport 12, no. 6 (2022): 80–86. http://dx.doi.org/10.12775/jehs.2022.12.06.007.

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Introduction: Endometrial hyperplastic processes (EHP) are characterized by recurrent course, high risk of malignancy, difficulties in diagnosing and predicting the course, which determines their great medical and social significance
 Objective: To evaluate the levels of proliferation markers Ki-67 and APRIL in serum of women with various forms of endometrial hyperplastic processes (EHP) and their correlation with clinical and anamnestic features.
 Materials and Methods: The study examined 95 women with endometrial hyperplasia and endometrial adenocarcinoma who underwent treatment in
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8

Abdullaiev, V. E., and A. M. Hryhorenko. "Features of instrumental research methods in combination of endometrial hyperplasia with chronic endometritis." Reports of Vinnytsia National Medical University 25, no. 4 (2021): 623–27. http://dx.doi.org/10.31393/reports-vnmedical-2021-25(4)-20.

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Annotation. Hyperplastic processes of the endometrium can be triggered by a chronic inflammatory process. In addition, the importance of the presence of a long hyperproliferative process in the endometrium to accelerate genome modification with significant negative consequences of the development of oncogynecological pathology has been proved. The above risks require the development of clear diagnostic criteria for endometrial hyperplastic processes at the stage of non-invasive instrumental diagnosis. The aim of the study was to establish the features of the impact of chronic endometritis on t
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9

Strakhovetska, Yuliya. "A role of chronic endometritis is in development of different forms of hyperplastic processes of endometrium." Perinatology and reproductology: from research to practice 4, no. 1 (2024): 77–82. https://doi.org/10.52705/2788-6190-2024-01-12.

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The objective:to set the clinical features of different forms of hyperplastic processes of endometrium for women in a perimenopausal period taking into account the role of chronic endometritis.Materials and methods. It is conducted clinical-and-laboratory inspection 100 patients with the uterine bleeding of different character and presence of echographic signs of pathology of endometrium. After an inspection which included clinical-and-laboratory and echographic methods, the separate diagnostic scraping off of uterus was conducted all patients under control hysteroscopy. Depending on the resul
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10

Khodjaeva, Aziza S. "Optimization of treatment tactics in patients with abnormal uterine bleeding on the background of benign hyperplastic processes in the uterus." Gynecology 21, no. 2 (2019): 55–57. http://dx.doi.org/10.26442/20795696.2019.2.190383.

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Aim. Optimization of management tactics for patients with abnormal uterine bleeding on the background of benign endometrial and myometrial hyperplastic processes (BEMH) using systemic enzyme therapy. Materials and methods. 90 female patients with BEMH were included. They were divided into three groups: group 1 - women with endometrial hyperplasia, group 2 - women with uterine myoma of small size (6-8 weeks) in combination with endometrial hyperplasia and group 3 - women with endometrial hyperplasia in combination with endometriosis. Systemic enzyme therapy drug was used. Results and conclusion
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11

Leshchova, Olga. "Hyperplastic processes of endometrium: clinic of different forms early in life." Perinatology and reproductology: from research to practice 4, no. 1 (2024): 51–56. https://doi.org/10.52705/2788-6190-2024-01-08.

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The objective: to set the clinical features of different forms of hyperplastic processes of endome-trium for the women of young age taking into account the role of chronic endometritis.Materials and methods. It was conducted clinical-and-laboratory inspection 100 patients to 30 years with the uterine bleeding of different character and presence of echographic signs of pathology of endometrium.Results. The analysis of the got data testifies that more frequent all gynaecological diseas-es met for patients with simple hyperplasia of endometrium without atypia in combination with chronic endometri
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12

Abramova, S., and D. Korobkov. "Modern idea of diagnostics and treatment of hyperplastic processes of endometrium at women in the premenopausal period." Bulletin of Science and Practice 456, no. 11 (12) (2016): 146–49. https://doi.org/10.5281/zenodo.166798.

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The paper discusses the problem of diagnosing endometrial hyperplasia in women premenopausal period. During the work, it was formed the best criteria for diagnosis of endometrial hyperplastic processes in perimenopausal women through the use of modern endoscopic, immunohistochemical techniques. The prospects of the use of immunohistochemical techniques in gynecologic practice. The study found that the study and analysis of hormone–receptor status in patients with hyperplastic processes of the endometrium prior to treatment in gynecological practice, is two things, first, hormone–receptor statu
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13

С., М. Корниенко. "Risk factors for recurrence of endometrial hyperplasia in women of late reproductive and premenopausal age." REPRODUCTIVE ENDOCRINOLOGY, no. 34 (April 30, 2017): 28–31. https://doi.org/10.18370/2309-4117.2017.34.28-31.

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According to many researchers, hyperplastic endometrial processes are not precancerous diseases. However, recurrent endometrial hyperplastic processes, as well as their combination with genital and extragenital pathologies, significantly increase the risk of malignant transformation of the endometrium. Late reproductive and premenopausal age is associated with an increase in the frequency of endometrial hyperplastic processes, extragenital pathology and operative interventions on the internal genitalia. The limited possibilities of conservative treatment in connection with concomitant diseases
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14

Benyuk, V. O., V. M. Goncharenko, Yu V. Kravchenko, O. V. Kalenska, and Niki Abedi Astaneg. "Modern aspects of the etiology and pathogenesis of hyperplastic endometrial processes." Reproductive health of woman 4 (May 31, 2021): 7–18. http://dx.doi.org/10.30841/2708-8731.4.2021.238156.

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The article presents modern approaches to the etiology, classification and pathogenesis of endometrial hyperplastic processes. Hyperplastic processes of the endometrium, representing an urgent medical and social problem, which is due to the peculiarities of the clinical manifestation of the disease (uterine bleeding), reduced reproductive potential, high recurrence rate, limited conservative treatment of this pathology in pre- and postmenopausal women, due to concomitant extragenital diseases and a high risk of malignancy.On the basis of new criteria of pathomorphological diagnostics, drawing
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15

V.O., Benyuk, Goncharenko V.M., Kravchenko Yu.V., Kalenska O.V., and Abedi Astaneg Niki. "Modern aspects of the etiology and pathogenesis of hyperplastic endometrial processes." Reproductive Health of Woman 4 (May 31, 2021): 7–18. https://doi.org/10.30841/2708-8731.4.2021.238156.

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The article presents modern approaches to the etiology, classification and pathogenesis of endometrial hyperplastic processes. Hyperplastic processes of the endometrium, representing an urgent medical and social problem, which is due to the peculiarities of the clinical manifestation of the disease (uterine bleeding), reduced reproductive potential, high recurrence rate, limited conservative treatment of this pathology in pre- and postmenopausal women, due to concomitant extragenital diseases and a high risk of malignancy. On the basis of new criteria of pathomorphological diagnostics, drawing
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16

Donisheva, Shoxsanam, Irodaxon Saxobova, and Dilbar Sulaymanova. "MODERN ASPECTS OF HYPERPLASTIC PROCESSES." MODERN SCIENCE AND RESEARCH 3, no. 1 (2024): 382–87. https://doi.org/10.5281/zenodo.10512056.

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<em>Accordingly, the goal is to determine the relationship of hyperplastic processes with premenopausal age and their manifestations in the form of abnormal uterine bleeding. The study was conducted on 50 premenopausal patients with a history of hyperplastic processes who were treated in the gynecological department of the first multidisciplinary clinic of Samarkand State Medical University during 2021-2022. The study used general clinical, laboratory, instrumental and statistical research methods. The main complaints upon admission to the hospital were heavy vaginal bleeding and pain, and in
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17

Akulich, N. S., V. М. Savickaya, and V. V. Dziadzichkina. "COMPARATIVE ANALYSIS OF DIAGNOSTIC CRITERIA FOR ENDOMETRIAL HYPERPLASTIC PROCESSES." Medical Journal, no. 3(77) (2021): 28–32. http://dx.doi.org/10.51922/1818-426x.2021.3.28.

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Endometrial hyperplastic processes are currently among the most common gynecological diseases, tend to a long, recurrent course, are characterized by the absence of specific, pathognomonic symptoms and the complexity of differential diagnosis. With a prolonged course without treatment, endometrial cancer develops in 25 % of cases against the background of benign endometrial changes. The diagnostic criteria allowing to refer the patient for separate diagnostic curettage are contradictory and not always reliable. The aim of this work was to study the informativeness of clinical data, indicators
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18

Khaskhachykh, Khaskhachykh Dmytro, and Valentin Potapov. "Impact of changes in the vaginal microbiome and chronic endometritis on the initiation of hyperplastic processes of the endometrium in women." Ukrainian Scientific Medical Youth Journal 134, no. 4 (2022): 22–28. http://dx.doi.org/10.32345/usmyj.4(134).2022.22-28.

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the article presents a review of the literature, which examines the impact of changes in the vaginal microbiome and chronic endometritis on the development of hyperplastic processes of the endometrium in women. Many studies have proven the undoubted role of these factors in the development of endometrial hyperplastic processes, such as atypical hyperplasia and endometrial polyposis. Chronic endometritis, on the background of which there was a course of endometrial hyperplasia, in 95.1% of women studied was caused by an infection of viral, bacterial or fungal origin. Numerous studies indicate t
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19

Ibadova, Sh T. "Structure of Hyperplastic Processes of the Uterus in Menopausal Women According to the Results of an Echographic Study." Ukraïnsʹkij žurnal medicini, bìologìï ta sportu 7, no. 4 (2022): 36–40. http://dx.doi.org/10.26693/jmbs07.04.036.

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The purpose of the study was to evaluate the results of ultrasound scanning in menopausal women with endometrial hyperplastic processes. Materials and methods. Ultrasound protocols of 67 menopausal women with uterine hyperplastic processes were analyzed. Endometrial imaging data were assessed as corresponding to focal endometrial hyperplasia in 53 (79.1%) women. Uterine fibroids in combination with endometrial hyperplasia were found in 42 (62.7%) menopausal patients. According to the transvaginal ultrasound protocols, only endometrial polyp was detected in 20.9% of women (n=14). Results and di
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20

NIKITINA, I. M., K. V. MYKYTYN, and N. YЕ GORBAN. "THE INFLUENCE OF AN INFECTIOUS AGENT ON THE DEVELOPMENT OF HYPERPLASTIC PROCESSES OF THE ENDOMETRY IN THE EARLY REPRODUCTIVE AGE." Scientific digest of association of obstetricians and gynecologists of Ukraine, no. 2(50) (September 22, 2022): 80–88. http://dx.doi.org/10.35278/2664-0767.2(50).2023.274997.

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The problem of hyperplastic processes of the endometrium (HPE) in women of reproductive age is a potential cause of reduced fertility and the risk of developing oncological pathology, which has been steadily increasing in recent years, attracting the increased attention of clinicians.&#x0D; The aim: to analyze the role of an infectious agent in the development of hyperplastic processes of the uterine mucosa in women of early reproductive age for the formation of risk groups for the occurrence of endometrial hyperplasia and polyps.&#x0D; Materials and Methods: 90 patients in early reproductive
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21

Krut, Y.Ya., N.A. Zemlyana, N.V. Gaidai, M.I. Pavliuchenko, and I.G. Amro. "The proliferation markers in patients with different forms of hyperplastic endometrial processes." Journal of Education, Health and Sport 12, no. 6 (2022): 80–86. https://doi.org/10.12775/JEHS.2022.12.06.007.

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<strong>Krut</strong>&nbsp;<strong>Y.Ya.,</strong><strong>&nbsp;Zemlyana</strong><strong>&nbsp;N.A.,</strong>&nbsp;<strong>Gaidai</strong><strong>&nbsp;N.V.,</strong><strong>&nbsp;Pavliuchenko</strong><strong>&nbsp;M.I.,</strong>&nbsp;<strong>Amro</strong><strong>&nbsp;I.G.</strong><strong>&nbsp;The p</strong><strong>roliferation markers in patients with different forms of hyperplastic endometrial processes</strong><strong>.</strong>&nbsp;<strong>Journal of Education, Health and Sport. 2022;12(</strong><strong>6</strong><strong>):</strong><strong>80-86</strong><strong>. eISSN 2391-8306. DOI </
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22

Orishchak, Irina. "Prognostic risk predictors of hyperplastic endometrial processes in women with reduced reproductive potential." Perinatology and reproductology: from research to practice 2, no. 1 (2022): 96–108. http://dx.doi.org/10.52705/2788-6190-2022-1-9.

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In the structure of female infertility, the uterine factor occupies one of the leading places and ranges from 25.20% to 42.30%, and in women with repeated unsuccessful attempts at in vitro fertilization, intrauterine pathology is detected in 45% of cases. In the structure of gynecological diseases, hyperplastic processes of the endometrium are 15–40%, and in women of reproductive age – 24.0–62.0%. The objective: to examine the risk predictors of the developing benign hyperproliferative pathology of the endometrium in women of reproductive age to improve preventive approaches of management of t
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23

Tolstanova, G. O. "Modern view of the problem of recurrent hyperplastic processes of the endometrium." HEALTH OF WOMAN, no. 7(153) (September 29, 2020): 45–50. http://dx.doi.org/10.15574/hw.2020.153.45.

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A review of current data on the problem of recurrent endometrial hyperplasia, presented in modern domestic and foreign literature, its place in the structure of gynecological morbidity, the impact on reducing fertility among women of childbearing age and the growth of cancer. The issues of existing classifications, their relevance and ease of use are considered. The main etiological factors and clinical and anamnestic factors of endometrial hyperplastic processes, prognostic influence of urogenital infections on endometrial pathology are highlighted. Possible mechanisms of pathogenesis are des
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24

С., М. Корнієнко. "Optimization of treatment of endometrial hyperplastic processes in the late reproductive period by hysteroscopic сold loop technique". REPRODUCTIVE ENDOCRINOLOGY, № 35 (21 червня 2017): 44–49. https://doi.org/10.18370/2309-4117.2017.35.44-49.

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The aim of the study was to evaluate the effectiveness of various methods of hyperplastic endometrium removing in late reproductive age women. Materials and methods. In the prospective cohort study 321 women 35&ndash;44 year aged with hyperplastic endometrium processes were selected by the continuous sample method. Depending on the method of treatment of this pathology, the patients were divided into two groups: the Ith group included 143 women whom, after hysteroscopic confirmation of the diagnosis, the hyperplastic endometrium was removed using the &ldquo;cold loop&rdquo; technique with the
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25

Popov, E. N., and D. A. Niauri. "Pathogenetically oriented endoscopy in the treatment of endometrial hyperplastic processes." Journal of obstetrics and women's diseases 50, no. 3 (2021): 44–46. http://dx.doi.org/10.17816/jowd95565.

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The experience of using electro destruction of the endometry in 60 patients showed that the method practically doesnt have any contraindications if applied for treating hyperplastic processes in endometry and helps to obtain stable therapeutic effect. It is reasonable to consider it particularly promising inpatients with relapsing endometrial hyperplasia resistant to hormonal therapy; in case of association with severe extragenital diseases electro destruction may appear an alternative both to hormonal therapy and surgical treatment.
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26

Benyuk, V. O., V. M. Goncharenko, and T. R. Nykoniuk. "Modern determinants of endometrium hyperplastic processes pathogenesis." HEALTH OF WOMAN, no. 5(111) (June 20, 2016): 137–42. http://dx.doi.org/10.15574/hw.2016.111.137.

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The objective: to еxplore the relationship between the activity of endometrial proliferation and the state of the local immune response in the uterus in the conditions berprestasi process. Patients and methods. Examined 228 women of reproductive and perimenopausal age with endometrial pathology using ultrasound and then performing hysteroresectoscopy. Determination of the concentrations of the cytokines IL-1, IL-2, IL-6 and TNF was performed by solid phase ELISA. Results. Found a trend that confirms the loss of sensitivity to hormones at the stage of malignancy of the endometrium and can be us
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27

Benyuk, V., V. Goncharenko, and O. Zabudskyi. "Features of the post-operating period after the endometrial ablation in post-menopausal aged women with hyperplastic processes of endometrium." HEALTH OF WOMAN, no. 6(142) (July 29, 2019): 60–67. http://dx.doi.org/10.15574/hw.2019.142.60.

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The paper presents the results of surgical treatment of 45 postmenopausal women with non-atypical forms of endometrial hyperplasia. The objective: is to establish the features of the postoperative period depending on the method of endometrial ablation in postmenopausal patients with endometrial hyperplastic processes. Materials and methods. The study included 45 women with non-atypical forms of endometrial hyperplasia: 25 women of postmenopausal age with non-atypical forms of endometrial hyperplasia, who were treated with hysteroscopic monopolar ablation of the endometrium and 20 women of post
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28

Allithy, Amal Nooredeen, Islam Mohamed Magdi Ammar, and Maisa Hashem Mohammed. "Diagnostic and Prognostic Values of PTEN Expression in Functional and Pathological Endometrial Biopsies." Asian Pacific Journal of Cancer Biology 7, no. 1 (2022): 21–27. http://dx.doi.org/10.31557/apjcb.2022.7.1.21-27.

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Background: Endometrial carcinoma is the most common gynecological malignancy in developed countries. About 80% of endometrial carcinomas are preceded by atypical endometrial hyperplasia. PTEN is a tumor suppressor gene involved in many vital intracellular biological processes. PTEN is altered in more than 45% of endometrial carcinomas. The aim of this study was to evaluate the value immunohistochemical expression of PTEN in normal, hyperplastic and neoplastic endometrial tissues. Methods: Ninety-two endometrial samples were enrolled in this study. They were classified into normal (n=6), hyper
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29

Prudnikov, P. M. "Combination of adenomyosis and hyperplastic processes of uterus: improvement tactics of diagnostics and treatment." HEALTH OF WOMAN, no. 7(123) (September 30, 2017): 132–34. http://dx.doi.org/10.15574/hw.2017.123.132.

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The objective: improvement of tactics of diagnostics and adenomyosis treatment in combination with hyperplastic processes of uterus. Patients and methods. We conducted examination and treatment of 100 patients with the established diagnosis of an adenomyosis in combination with hyperplastic processes of uterus. Patients are divided into 2 groups depending on option of conservative therapy. Results. Results of the conducted researches allow to allocate comparative aspects of conservative treatment of an adenomyosis in combination with hyperplastic processes of uterus by way of use of endometria
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30

Zemlianiy, Yaroslav, and Natalie Zemlyana. "Features of hyperplastic processes of the endometrium in the presence of arterial hypertension." Journal of Education, Health and Sport 42, no. 1 (2023): 123–29. http://dx.doi.org/10.12775/jehs.2023.41.01.010.

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Introduction: The relevance of studying endometrial hyperplastic processes (EHP) is due to their prevalence, impact on quality of life and high risk of malignancy. The structure of EHP takes from 20 to 40% in the pathology of reproductive system in women.&#x0D; Objective: To evaluate the clinical and morphological features of hyperplastic processes of the endometrium in the presence of arterial hypertension.&#x0D; Materials and Methods: 96 women with endometrial hyperplastic processes were examined during the study. The first group consisted of 57 women with endometrial hyperplasia with arteri
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31

Шешукова, Н. А., И. О. Макаров, and Т. В. Овсянникова. "Preventive maintenance of hyperplastic endometrial processes." Reproductive Endocrinology, no. 8 (December 14, 2012): 18. http://dx.doi.org/10.18370/2309-4117.2012.8.18-22.

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32

Татарчук, Т. Ф., Л. В. Калугина, and Т. Н. Тутченко. "Hyperplastic processes of endometrium: what's new?" Reproductive Endocrinology, no. 25 (October 25, 2015): 7. http://dx.doi.org/10.18370/2309-4117.2015.25.7-13.

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33

Armen, D., K. Liana, B. Zlata, C. Sergey, O. Elena, and O. Igor. "Genetic Determinants in Endometrial Hyperplastic Processes." Journal of Minimally Invasive Gynecology 17, no. 6 (2010): S128. http://dx.doi.org/10.1016/j.jmig.2010.08.464.

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34

Orazov, M. R., V. Е. Radzinskiy, M. B. Khamoshina, I. A. Mullina, and Yu S. Artemenko. "«VULNERABLE» ENDOMETRIUM: A MODERN VIEW ON THE PATHOGENESIS AND PATHOGENETIC THERAPY OF ENDOMETRIAL HYPERPLASTIC PROCESSES." Reproductive Medicine, no. 3(48) (September 20, 2021): 54–60. http://dx.doi.org/10.37800/rm.3.2021.54-60.

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Relevance: Endometrium is a unique human tissue with a strong regenerative potential which is implemented after desquamation during each menstrual cycle. At that, regeneration in the endometrium is not accompanied by scarring. Endometrial hyperplasia as a variant of defect transformation is a widespread disease which remains an urgent problem of modern medicine. In recent years, endometrial hyperplasia is becoming more common among patients of reproductive age. This problem is even more significant due to the spread of endometrial cancer in developed countries, and endometrial hyperplasia bein
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35

Tsyndrenko, Nataliia, Mykola Lyndіn, Kateryna Sikora, et al. "ER and COX2 expression in endometrial hyperplasia processes." Medicine 102, no. 33 (2023): e34864. http://dx.doi.org/10.1097/md.0000000000034864.

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Endometrial hyperplastic processes (EHPs) encompass various morphological changes, characterized by an increased ratio of endometrial glands to stroma. These changes manifest as endometrial hyperplasia (EH) and endometrial polyps. The objective of this study was to investigate the expressions of ER and Cyclooxygenase-2 (COX2) in EH and endometrial polyps, and determine their correlation with histological and anthropometric parameters. Tissue samples were obtained during hysteroresectoscopy and divided into 3 groups: non-atypical EH, glandular EP, and glandular-fibrous EP. We examined the immun
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36

Sadugov, Yurii. "Influence of excess body weight on tactics of maintaining women of reproductive age with hyperplastic processes an endometrium." Perinatology and reproductology: from research to practice 1, no. 3 (2021): 116–23. http://dx.doi.org/10.52705/2788-6190-2021-3-12.

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The objective: decline of frequency of relapses of hyperplastic processes of endometrium for the women of reproductive age with surplus mass of body on the basis of improvement and introduction of algorithm of treatment-and-prophylactis and prognostic measures. Materials and methods. The conducted researches carried stage-by-stage character. So, on I stage the analysis of clinical – anamnestic, hormonal and metabolic features of patients of reproductive age with surplus mass of body and hyperplastic processes of endometrium is a 1 group (n=90), patients with surplus mass of body, but without t
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37

Abramova, S., O. Gladkova, L. Zaidulina, I. Syatkina, and E. Surgaeva. "Diagnostics and Treatment of Hyperplastic Endometrial Processes in Women in the Menopausal Transition." Bulletin of Science and Practice 5, no. 5 (2019): 73–77. http://dx.doi.org/10.33619/2414-2948/42/09.

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His article discusses the problems of diagnosis of diffuse hyperplastic processes of the endometrium in women in the menopausal transition. Endometrial hyperplasia is a heterogeneous set of pathological processes, ranging from benign proliferation to monoclonal tissue proliferation. During the study, the most optimal criteria for the diagnosis of endometrial hyperplasia in women during the transition to menopause based on the use of a modern diagnostic complex (immunohistochemical and endoscopic technologies) were selected and formed. Endometrium is a hormone–sensitive, cyclically renewed tiss
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38

Atykanov, A. O., G. U. Asymbekova, and A. A. Masybaeva. "LIPID PEROXIDATION AND ANTIOXIDANT PROTECTION SYSTEM IN WOMEN WITH ENDOMETRIAL HYPERPLASTIC PROCESSES." Ulyanovsk Medico-biological Journal, no. 4 (December 10, 2019): 44–49. http://dx.doi.org/10.34014/2227-1848-2019-4-44-49.

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The paper presents quantitative indicators of lipid peroxidation (LP) products and antioxidant support network (ASN) in blood plasma in women with various histological forms of endometrial hyperplastic processes (EHPs). The goal of the paper is to assess the state of LP processes and ASN in women of reproductive age with various forms of EHPs. Materials and Methods. The trial enrolled 137 women of reproductive age: 112 women with endometrial hyperplasia (EH) and 25 women with uterine cavity synechia without EH. Conclusion. In case if EH progresses from a simple atypical form to adenocarcinoma,
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39

Tzvelev, Ju V., and A. B. Ilyin. "The diagnostics and treatment of dishormonal mammal hyperplasia in uterine myoma patients." Journal of obstetrics and women's diseases 48, no. 2 (1999): 30–34. http://dx.doi.org/10.17816/jowd88077.

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In gynecologic patients with internal genitalia diseases (endometriosis, uterine myoma) the frequency of mammal hyperplasia makes up to 60- 95%. The research aim was to study the effectiveness of conservative therapy with gestagens (norcolut, orgametril) application in benign hyperplastic mammal processes management in patients with uterine myomas. The effectiveness of gestagens application in patients with uterine myomas with coexisting dyshormonal mammal hyperplasia is proved.
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40

Strakhovetska, Yuliya. "The women of postmenopausal age have features of hyperplastic processes of endometrium." Perinatology and reproductology: from research to practice 4, no. 3-1 (2024): 91–98. https://doi.org/10.52705/2788-6190-2024-03.1-13.

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The objective: study clinical­and­anamnestic features of hyperplastic processes of endometrium for the women of postmenopausal age.Materials and methods. 90 women were inspected with hyperplasia of endometrium in postmenopause (basic group). Distributing of patients a morphological form served as a criterion on groups. Among inspected glandular hyperplasia of endometrium was diagnosed in 32,2% patients, in 45,6% are endometrial polyps, in 22,2% is adenomatous hyperplasia of endometrium. A control group was made by 30 patients in postmenopause without hyperplasia of endometrium.Results. Most wo
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41

Abdullaiev, V., and A. Hryhorenko. "Results of treatment of endometrial hyperplasia with the use of non-steroidal anti-inflammatory agents against the background of chronic endometritis and without accompanying inflammatory process." Bukovinian Medical Herald 26, no. 3 (103) (2022): 3–8. http://dx.doi.org/10.24061/2413-0737.xxvi.3.103.2022.1.

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The paper examines the treatment results of women with non-atypical hyperplastic endometrial processes with the use of anti-inflammatory drugs for a long time. The purpose of our study was to evaluate the effectiveness of the proposed treatment regimen depending on the type of hyperplastic processes and their connection with chronic inflammatory processes in the endometrium. Material and methods. We examined 101 women, of which 29 women with hyperplastic processes without accompanying chronic endometritis were included in experimental group №1, 49 women with a combination of hyperplastic proce
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42

A., O. Semenyuk. "TACTIC OF CONDUCT OF WOMEN OF GENESIAL AGE WITH THE HYPERPLASTIC PROCESSES OF ENDOMETRIUM ON BACKGROUND SURPLUS MASS OF BODY." Reproductive health of woman 3 (September 30, 2020): 28–31. https://doi.org/10.30841/2708-8731.3.2020.215009.

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<strong>The objective:</strong>&nbsp;decline of frequency of relapses of hyperplastic processes of endometrium for the women of genesial age with surplus mass of body on the basis of improvement and introduction of algorithm of treatment-and-prophylactis and prognostic measures. <strong>Materials and methods.</strong>&nbsp;The conducted researches carried stage-by-stage character. So, on I stage the analysis of clinical-anamnestic, hormonal and metabolic features of patients of genesial age with surplus mass of body and hyperplastic processes of endometrium is a 1 group (n=90), patients with s
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43

Nikitina, I. M., K. V. Mуkуtуn, and Yu V. Diadiushka. "Analysis of risk factors for the development of hyperproliferative endometrial processes in women of reproductive age." Bukovinian Medical Herald 26, no. 2 (102) (2022): 27–31. http://dx.doi.org/10.24061/2413-0737.xxvi.2.102.2022.5.

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Based on clinical and statistical analysis, a study of the leading etiopathogenetic factors in the development of hyperplastic processes of the endometrium in patients of reproductive age was carried out.The aim of the study: to study the risk factors for hyperplasia and endometrial polyps in women of early reproductive age.Materials and methods. Clinical and statistical analysis of 120 patients of active reproductive age with verified atypical hyperproliferative pathology of the endometrium (hyperplasia and endometrial polyps) was included in the main group. The main group was divided into su
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44

Boychuk, Alla V., Tetiana V. Vereshchahina, and Iryna M. Nikitina. "ESTIMATION OF RELATIVE RISK OF DEVELOPMENT AND INFORMATIVENESS OF DIAGNOSTIC METHODS OF HYPERPROLIFERATIVE PROCESSES OF ENDOMETRIUM." Wiadomości Lekarskie 73, no. 9 (2020): 2004–9. http://dx.doi.org/10.36740/wlek202009220.

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The aim: To conduct a comparative analysis of the results of ultrasound and hysteroscopic examinations with further histopathological findings and the clinical and anamnestic features of patients with hyperproliferative pathology in order to determine the etiopathogenetic mechanisms of the development of endometrial pathological processes. Materials and methods: We studied 119 medical records of patients of the Gynecological Department of Minipal Non-Commercial Enterprise “Ternopil Municipal City Hospital No. 2”, who applied for medical assistance because of benign endometrial hyperplasia in t
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45

Abramova, S., O. Gladkova, L. Zaidulina, I. Syatkina, and E. Surgaeva. "Diagnostics and Treatment of Hyperplastic Endometrial Processes in Women in the Menopausal Transition." Bulletin of Science and Practice 5, no. 5 (2019): 73–77. https://doi.org/10.33619/2414-2948/42/09.

Full text
Abstract:
His article discusses the problems of diagnosis of diffuse hyperplastic processes of the endometrium in women in the menopausal transition. Endometrial hyperplasia is a&nbsp;heterogeneous set of pathological processes, ranging from benign proliferation to monoclonal tissue proliferation. During the study, the most optimal criteria for the diagnosis of endometrial hyperplasia in women during the transition to menopause based on the use of a modern diagnostic complex (immunohistochemical and endoscopic technologies) were selected and formed. Endometrium is a hormone&ndash;sensitive, cyclically r
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46

Vereshchahina, Tetiana V., Alla V. Boychuk, Yuliia B. Yakymchuk, Iryna M. Nikitina, and Tetiana V. Datsko. "MORPHOLOGICAL CHANGES OF THE ENDOMETRIUM IN HYPERPLASTIC PROCESS IN WOMEN OF REPRODUCTIVE AGE." Wiadomości Lekarskie 74, no. 3 (2021): 388–94. http://dx.doi.org/10.36740/wlek202103102.

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The aim: To conduct a morphological study of endometrial tissue to identify changes characteristic of viral lesions to develop improved antirelapse treatment of HPE in women of reproductive age. Materials and methods: We surveyed 90 patients of the gynecological department who sought medical for hyperplastic processes of the endometrium in reproductive age. All women underwent hysteroscopy, the resulting material was subjected to morphological examination. Results: It became known that the virus is involved in the pathogenesis of endometrial hyperplasia. It is likely that it exists in epitheli
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47

Bakhtiyarov, K. R., A. V. Apsalyamova, Natalia A. Bogacheva, and A. L. Parsyan. "TACTICS OF MANAGEMENT OF PATIENTS WITH ATYPICAL ENDOMETRIAL HYPERPLASIA (LITERATURE REVIEW)." V.F.Snegirev Archives of Obstetrics and Gynecology 6, no. 1 (2019): 15–18. http://dx.doi.org/10.18821/2313-8726-2019-6-1-15-18.

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In the past few years, there has been a gain in the prevalence of hyperplastic processes of the reproductive system in women, among which atypical endometrial hyperplasia (AEH) occupies a special place. Such peculiarities of the clinical manifestation of this disease as the high prevalence, relapsing course, reduced reproductive function and high risk of malignancy reflect the urgency of the problem of prevention and increasing the effectiveness of treatment of endometrial hyperplastic processes. The purpose of the study is to analyze the data presented in modern literature on the tactics of m
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48

Farhan, Tarek, Alaa Eddin Nwilati, Anas Al-Farhan, and Roger Albert. "ENDOMETRIAL HYPERPLASTIC PROCESSES, POLYPS AND CANCER: A STUDY OF THE RELATIONSHIP AND CONSEQUENCES." Norwegian Journal of development of the International Science, no. 107 (April 26, 2023): 30–33. https://doi.org/10.5281/zenodo.7878353.

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<strong>Abstract</strong> This article examines the relationship between endometrial hyperplastic processes and cancer, as well as current approaches to diagnosis and treatment, taking into account international practice and statistics. Endometrial hyperplasia is one of the risk factors for endometrial cancer, especially in the presence of atypia. Ultrasound examination, hysteroscopy and histological examination of biopsy material are used to identify and determine the degree of hyperplasia and atypia. Treatment can be conservative or surgical, depending on the degree of hyperplasia, the prese
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49

ZEMLIANIY, Yaroslav, and Natalie ZEMLYANA. "Features of hyperplastic processes of the endometrium in the presence of arterial hypertension." Journal of Education, Health and Sport 41, no. 1 (2023): 123–29. https://doi.org/10.12775/JEHS.2023.41.01.010.

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<strong>ZEMLIANIY, Yaroslav and ZEMLYANA, Natalie. Features of hyperplastic processes of the endometrium in the presence of arterial hypertension</strong><strong>. </strong><strong>Journal of Education, Health and Sport. 2023;4</strong><strong>1</strong><strong>(1):1</strong><strong>23</strong><strong>-</strong><strong>129</strong><strong>. eISSN 2391-8306. DOI </strong><strong>http://dx.doi.org/10.12775/JEHS.2023.41.01.0</strong><strong>10</strong> <strong>https://apcz.umk.pl/JEHS/article/view/45</strong><strong>368</strong> <strong>https://zenodo.org/record/8218451</strong> &nbsp; &nbsp; &nb
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50

Marichereda, V. G., N. A. Bykovа, V. V. Bubnov, et al. "THE ANALYSIS OF METHYLATION OF DNA PROMOTER OF SFRP2 GENE IN PATIENTS WITH HYPERPLASTIC PROCESSES OF THE ENDOMETRIUM." Experimental Oncology 40, no. 2 (2018): 109–13. http://dx.doi.org/10.31768/2312-8852.2018.40(2):109-113.

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The hyperplastic processes of the endometrium can arise not only against the background of excessive influence of estrogen, but also against the background of epigenetic damages that affect apoptosis, cell proliferation, differentiation, and adhesion, and DNA reparation. The aim of our study was to investigate and analyze the status of methylation of the promoter of SFRP2 gene in patients with hyperplastic processes of the endometrium. Materials and Methods: The study groups were the following: I — patients with endometrial hyperplasia (EH, n = 9); II — patients with endometrial intraepithelia
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