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Journal articles on the topic 'Hypertension-Black Moroccan- Calcium Channel Blockers'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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1

Sara, SALOUI, ELHOUARI Bouchra, and KISSA Jamila. "Amlodipine Induced Gingival Overgrowth, Unusual Defect and The Impact of Oral Environment: A Case Report." Journal of Dentistry, Oral Disorders & Therapy 7, no. 1 (2019): 1–5. http://dx.doi.org/10.15226/jdodt.2019.001103.

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Introduction: Calcium-channel blockers are known for their buccal side effect as Gingival Overgrowth (GO). Although Amlodipine is considered a safe drug, it may induce gingival overgrowth for some individuals, inducing then, an aesthetic prejudice for the patient and causing serious managerial problems for clinicians. This case reports unusual defects of Amlodipine-induced gingival overgrowth, with a large gingival mass that almost completely disappeared only after improving the buccal environment. Case Study: A 51-year old Moroccan woman was complaining of gingival bleeding swelling. The exam

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Ullah, Aman, and Hafiz Muhammad Irfan. "Search for Potential Calcium Channel Blockers From Medicinal Plants." Phytopharmacological Communications 1, no. 1 (2021): 65–75. http://dx.doi.org/10.55627/ppc.001.01.0103.

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Hypertension is a global disease and its prevalence is estimated to be about one billion which is projected to increase to 1.54-1.58 billion by 2025. It is estimated that hypertensive patients account for about 31.1 % of the global adult population in 2010. Current treatment options include angiotensin-converting enzyme inhibitors (ACEIs) such as Captopril, and Enalapril which is first-line drugs for hypertensive patients that are under 55 years old, angiotensin receptor antagonists (ARA) such as candesartan and telmisartan that are used in patients who are intolerant to ACEIs, β-blockers (met

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3

Rida, E., A. Soulaymani, H. Hami, and M. Abdelrhani. "Epidemiology of Hypertension in the Prefecture of Figuig, Morocco." Rwanda Medical Journal 79, no. 3 (2022): 38–50. http://dx.doi.org/10.4314/rmj.v79i3.5.

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   BACKGROUND: Hypertension continues to be a public health problem with devastating consequences globally, particularly in developing countries where there is an acute paucity of hypertension data.The aim of this study was to describe the epidemiological, clinical, and treatment characteristics of hypertensive patients in the prefecture of Figuig, Morocco. METHODS: Retrospective analysis of hypertensive patients’ medical records from 2010 to 2020. The diagnosis, treatments, and complications were reported by physicians and cardiologists. Data analysis was made accordin

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4

Moura, Ana Flávia, José A. Moura-Neto, Cibele Isaac Saad Rodrigues, et al. "Resistant hypertension: Prevalence and profile of patients followed in a university ambulatory." SAGE Open Medicine 9 (January 2021): 205031212110208. http://dx.doi.org/10.1177/20503121211020892.

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Background: Hypertension affects about 36 million Brazilians. It is estimated that 10%–20% of these have resistant hypertension. These patients are at an increased risk of early target organ damage, as well as cardiovascular and renal events. Objective: To estimate the prevalence of resistant hypertension in a specialized outpatient clinic, to describe the sociodemographic and clinical characteristics of these patients, and to identify possible factors associated with resistant hypertension. Methods: Data collection from medical records of hypertensive patients treated using oral antihypertens

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5

Egan, Brent M., Jianing Yang, Michael K. Rakotz, et al. "Self-Reported Antihypertensive Medication Class and Temporal Relationship to Treatment Guidelines." Hypertension 79, no. 2 (2022): 338–48. http://dx.doi.org/10.1161/hypertensionaha.121.17102.

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The greater antihypertensive responses to initial therapy with calcium channel blockers (CCBs) or thiazide-type diuretics than renin-angiotensin system blockers as initial therapy in non-Hispanic Black (NHB) adults was recognized in the US High BP guidelines from 1988 to 2003. The 2014 Report from Panel Members Appointed to the Eighth Joint National Committee (2014 aJNC8 Report) and the 2017 American College of Cardiology/American Heart Association High Blood Pressure Guideline were the first to recommend CCBs or thiazide-type diuretics rather than renin-angiotensin system blockers as initial

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6

Siham El Khayat, Selma, Camille Maadjhou Mba, Armand Mbanya, Jean CLAUDE Mbanya, and El Ghali Mohamed Benouna. "SYNERGIA-MOROCCO: EFFECTIVENESS OF HYPERTENSION MANAGEMENT WITH AN AMLODIPINE AND PERINDOPRIL ARGININE-BASED STRATEGY IN MOROCCO: STUDY DESIGN AND PRELIMINARY DATA." Journal of Hypertension 42, Suppl 1 (2024): e13. http://dx.doi.org/10.1097/01.hjh.0001019444.12431.fc.

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Objective: In Morocco, 1 in 3 adults currently live with hypertension; over 70%1 are not aware or not effectively treated. Among treated hypertensive patients, many receive monotherapy and remain uncontrolled. WHO recommends the addition of an angiotensin-converting enzyme inhibitor/angiotensin-receptor blocker or a diuretic in patients who are uncontrolled on a calcium-channel blocker and a monthly follow-up after initiation until patients reach targets. However, there is limited evidence from real-world observational studies in Morocco on the effectiveness of this approach on blood pressure

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7

Helmer, Allison, Nicole Slater, and Sean Smithgall. "A Review of ACE Inhibitors and ARBs in Black Patients With Hypertension." Annals of Pharmacotherapy 52, no. 11 (2018): 1143–51. http://dx.doi.org/10.1177/1060028018779082.

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Objective: To review current guidelines and recent data evaluating the efficacy and safety of angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) in black hypertensive patients. Data Sources: Articles evaluating race-specific outcomes in hypertension were gathered using a MEDLINE search with keywords black, African American, ACE inhibitor, angiotensin receptor blocker, angiotensin system, and hypertension. Studies published from 2000 through April 2018 were reviewed. Study Selection and Data Extraction: Six guidelines, 8 monotherapy publications, and 5 combi

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Perez, Alexandra, Andrea Levin, and Nowrin Alam. "A Comparison of the Use of Clinical-Guideline–Recommended Antihypertensive Regimens in Mexican American, Non-Hispanic Black, and Non-Hispanic White Adults With Type 2 Diabetes and Hypertension in the United States." Diabetes Educator 42, no. 6 (2016): 739–47. http://dx.doi.org/10.1177/0145721716666680.

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Purpose The purpose of this study was to determine the use of clinical-guideline–recommended antihypertensive regimens among Mexican Americans (MAs) and non-Hispanic blacks and whites with type 2 diabetes and hypertension. Methods A secondary data analysis based on National Health and Nutrition Examination Survey 2003-2012 cohort data included 1857 noninstitutionalized civilian MA, black, and white adults with type 2 diabetes and hypertension. Unadjusted and adjusted 2-way analysis of variance models evaluated whether there was a difference in the use of recommended antihypertensive regimens a

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9

Harlalka, S., U. K. Roy, G. Majumdar, K. Das, and P. Mandal. "An Open Label Prospective Study on Evaluation of Safety and Efficacy of Cilnidipine Over Amlodipine in Stage 1 Hypertensive Patients." Kathmandu University Medical Journal 18, no. 1 (2020): 42–48. http://dx.doi.org/10.3126/kumj.v18i1.33359.

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Background Calcium channel blockers are considered the first line drug over renin-angiotensin-aldosterone system inhibitor in black population and with renin-angiotensin-aldosterone system inhibitor in non-black population with Hypertension. Amlodipine has longer biological half life and lower potential to stimulate SNS. But, is associated with reflex tachycardia and pedal oedema. Cilnidipine has potent inhibitory both on voltage gated L-type and N-type calcium channels with better anti-proteinuric effect and good tolerability. Hence, our study compared the efficacy, safety and compliance of c

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10

Jaouad, Nguadi Hajar Elouartassi Badre Elboussaadani Bouthayna Mesmoudi Anas Hadari Ratiba Jennane H. Zineddine Meryem Bennani Jamal Kheyi Najat Mouine, and Bouzerda Hicham Bouzelmate Ilyass Asfalou Maha Raissouni Nabil Berrada Zouhair Lakhal Aatif Benyass and Ali Chaib Abdelmajid. "TREATMENT OF HIGHBLOOD PRESSURE IN A HETEROGENEOUS BLACK POPULATION: STUDY OF 50 CASES." January 22, 2020. https://doi.org/10.5281/zenodo.3687496.

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11

Lin, Pi‐I Debby, Sheryl Rifas‐Shiman, John Merriman, et al. "Trends of Antihypertensive Prescription Among US Adults From 2010 to 2019 and Changes Following Treatment Guidelines: Analysis of Multicenter Electronic Health Records." Journal of the American Heart Association, April 19, 2024. http://dx.doi.org/10.1161/jaha.123.032197.

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Background Guidelines for the use of antihypertensives changed in 2014 and 2017. To understand the effect of these guidelines, we examined trends in antihypertensive prescriptions in the United States from 2010 to 2019 using a repeated cross‐sectional design. Methods and Results Using electronic health records from 15 health care institutions for adults (20–85 years old) who had ≥1 antihypertensive prescription, we assessed whether (1) prescriptions of beta blockers decreased after the 2014 Eighth Joint National Committee (JNC 8) report discouraged use for first‐line treatment, (2) prescriptio

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12

Pakkir Maideen, Naina Mohamed, Rajkapoor Balasubramanian, and Sambathkumar Ramanathan. "Nigella Sativa (Black seeds), a Potential herb for the Pharmacotherapeutic Management of Hypertension - A Review." Current Cardiology Reviews 16 (November 10, 2020). http://dx.doi.org/10.2174/1573403x16666201110125906.

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: Hypertension is one of the leading risk factors of stroke, myocardial infarction and untimely death. The prevalence of hypertension is extremely high among the global population and many of them depend on modern medicines to manage their blood pressure. The modern antihypertensive medications include angiotensin converting enzyme inhibitors (ACEIs), angiotensin II receptor blockers (ARBs), calcium channel blockers (CCBs), diuretics, betaadrenergic blockers, direct renin inhibitors, direct acting vasodilators, alpha-adrenergic blockers and centrally acting drugs that are associated with many

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13

Lackland, Daniel T., Christopher P. Cannon, Brent M. Egan, et al. "Abstract 3466: Hypertension Treatment and Control Among Patients Hospitalized with Heart Failure: An Analysis of Get With The Guidelines Heart Failure." Circulation 116, suppl_16 (2007). http://dx.doi.org/10.1161/circ.116.suppl_16.ii_784-a.

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Background: Hypertension is a major factor associated with heart failure (HF).While effective blood pressure (BP) control is recommended in patients with HF, little is known regarding treatment and control rates in these patients. Methods: The analyses assessed HF patients from 195 hospitals participating in the GWTG-HF quality improvement program from January 2005 through September 2006. Patients with hypertension were assessed for number and type of hypertension treatment as well as BP control rates. Analyses were stratified by race-sex groups with multivariate logistic regression models usi

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14

Gordon Perue, Gillian, Hao Ying, Antonio Bustillo, et al. "Ten‐Year Review of Antihypertensive Prescribing Practices After Stroke and the Associated Disparities From the Florida Stroke Registry." Journal of the American Heart Association 12, no. 22 (2023). http://dx.doi.org/10.1161/jaha.123.030272.

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Background Guideline‐based hypertension management is integral to the prevention of stroke. We examine trends in antihypertensive medications prescribed after stroke and assess how well a prescriber's blood pressure (BP) medication choice adheres to clinical practice guidelines (BP‐guideline adherence). Methods and Results The FSR (Florida Stroke Registry) uses statewide data prospectively collected for all acute stroke admissions. Based on established guidelines, we defined optimal BP‐guideline adherence using the following hierarchy of rules: (1) use of an angiotensin‐converting enzyme inhib

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15

Mochari-Greenberger, Heidi, and Lori Mosca. "Abstract P049: Race/Ethnic Differences in Patterns of Antihypertensive Medication Uptake and Clinical Outcomes among Hospitalized Diabetic Patients with Hypertension." Circulation 129, suppl_1 (2014). http://dx.doi.org/10.1161/circ.129.suppl_1.p049.

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Background: Hypertension increases the risk of complications in patients with diabetes. Race/ethnic differences in the uptake of antihypertensive medications may contribute to disparities in clinical outcomes, but this has not been formally evaluated. We aimed to assess patterns of antihypertensive medication prescription by race/ethnic group and the association with clinical outcomes among hospitalized diabetic patients with hypertension. Methods: This was a 1 year prospective study of individuals with existing diabetes and hypertension (N=1126, 42% black/Hispanic [minority]; 39% female) that

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16

Husain, Saima, Mari K. Nishizaka, Eduardo Pimenta, Krishna K. Gaddam, Suzanne Oparil, and David A. Calhoun. "Abstract 4428: Similar Response to Spironolactone in Whites and African American Patients with Resistant Hypertension." Circulation 118, suppl_18 (2008). http://dx.doi.org/10.1161/circ.118.suppl_18.s_887-d.

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Primary aldosteronism (PA) is a common cause of resistant hypertension with a prevalence of approximately 20%. Spironolactone is the drug of choice for the medical management of patients with PA. Blacks have been reported to have low-renin HTN and respond better to diuretics and calcium channel blockers. Racial differences in response to spironolactone in patients with resistant hypertension have not been previously described. Consecutive subjects referred to the University of Alabama at Birmingham hypertension clinic for resistant hypertension had been evaluated with a plasma aldosterone conc

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17

Nguyen, Andrew, Jonathan Le, Tzu Yu Huang, Patrick Botting, Susan Cheng, and Joseph Ebinger. "Abstract P400: Adherence to First Line Antihypertensive Medication Prescription Recommendations by Race." Hypertension 81, Suppl_1 (2024). http://dx.doi.org/10.1161/hyp.81.suppl_1.p400.

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Introduction: The burden of hypertension is not felt uniformly across the population, with non-Hispanic Black (NHB) adults experiencing the highest rates of hypertension-attributable mortality. The 2017 AHA guidelines recommend calcium channel blockers (CCBs) and thiazide-like diuretics as initial medications for NHB patients, with ACE/ARBs a first line recommendation for other populations. It remains unclear to what degree providers adhere to these race-specific recommendations. Methods: We examined electronic health record data of all hypertensive adults (first blood pressure >140/90 mmHg

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18

Sinnott, Sarah-Jo, Ian J. Douglas, Liam Smeeth, Elizabeth Williamson, and Laurie A. Tomlinson. "First line drug treatment for hypertension and reductions in blood pressure according to age and ethnicity: cohort study in UK primary care." BMJ, November 18, 2020, m4080. http://dx.doi.org/10.1136/bmj.m4080.

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Abstract Objective To study whether treatment recommendations based on age and ethnicity according to United Kingdom (UK) clinical guidelines for hypertension translate to blood pressure reductions in current routine clinical care. Design Observational cohort study. Setting UK primary care, from 1 January 2007 to 31 December 2017. Participants New users of angiotensin converting enzyme inhibitors/angiotensin receptor blockers (ACEI/ARB), calcium channel blockers (CCB), and thiazides. Main outcome measures Change in systolic blood pressure in new users of ACEI/ARB versus CCB, stratified by age

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19

Jiao, Tianze, Robert W. Platt, Antonios Douros, and Kristian B. Filion. "Prescription Patterns for the Use of Antihypertensive Drugs for Primary Prevention among Patients with Hypertension in the United Kingdom." American Journal of Hypertension, August 27, 2021. http://dx.doi.org/10.1093/ajh/hpab137.

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Abstract Background Several antihypertensive drugs are available for the primary prevention of cardiovascular disease (CVD). However, existing evidence on prescription patterns was primarily generated among patients at high CVD risk with short-term follow-up, and failed to capture impacts of time and patient characteristics. Our objective was therefore to describe longitudinal prescription patterns for antihypertensive drugs for the primary prevention of CVD among patients with arterial hypertension in the United Kingdom. Methods This population-based cohort study used data from the Clinical P

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20

Stamm, Brian, Regina Royan, Jinhong Cui, et al. "Abstract TMP97: Temporal Trends in Black-White Differences of Antihypertensive Treatment in Individuals With and Without History of Stroke: Reasons for Geographic and Racial Differences in Stroke (REGARDS)." Stroke 55, Suppl_1 (2024). http://dx.doi.org/10.1161/str.55.suppl_1.tmp97.

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Introduction: In 2014, the Eighth Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC8) included race-specific recommendations for antihypertensive treatments (e.g. calcium channel blockers [CCBs] for Black persons). The impact of these guidelines on anti-hypertensive regimen changes over time, and if this varied by prevalent stroke status, is unclear. Methods: REGARDS participants reporting anti-hypertensive medications with and without history of stroke who completed an in-home examination in 2003-2007 (Visit 1) or 2013-2016 (Visit 2) were

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RIDDHI, NAGPURE. "PAEDIATRIC HYPERTENSION." April 27, 2025. https://doi.org/10.5281/zenodo.15380380.

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<strong>PAEDIATRIC HYPERTENSION: A CLINICAL REVIEW OF EMERGING RISK FACTORS AND MODERN MANAGEMENT STRATEGIES</strong> An article by <strong>RIDDHI NAGPURE</strong> under the guidance of <strong>MUKTARALI KYZY BEGIMAI</strong> Ma’am (Faculty of paediatrics and childhood diseases).   <strong>ABSTRACT</strong> Hypertension in children and adolescents has become a primary diagnosis, presenting significant challenges for healthcare providers. The prevalence rates have increased significantly, with rates rising to 9.43% among children with obesity and 14.7% in those with severe obesity. T

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