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Journal articles on the topic 'Hypertension Nephrosclerosis'

Author: Grafiati

Published: 4 June 2021

Last updated: 6 February 2022

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1

Ono, Hidehiko, and Yuko Ono. "NEPHROSCLEROSIS AND HYPERTENSION." Medical Clinics of North America 81, no. 6 (1997): 1273–88. http://dx.doi.org/10.1016/s0025-7125(05)70582-4.

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2

Freedman, Barry I., Samy S. Iskandar, and Richard G. Appel. "The link between hypertension and nephrosclerosis." American Journal of Kidney Diseases 25, no. 2 (1995): 207–21. http://dx.doi.org/10.1016/0272-6386(95)90001-2.

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3

Razzaque, M. S., M. Cheng, Y. Horita, M. Nishihara, T. Harada, and T. Taguchi. "Immunohistochemical Analysis of Type III and IV Collagens in Tubulointerstitial Damage in Human Benign Nephrosclerosis." Journal of International Medical Research 23, no. 6 (1995): 480–86. http://dx.doi.org/10.1177/030006059502300610.

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Prolonged hypertension causes structural changes including glomerulosclerosis and tubulointerstitial damage of the kidney, termed benign nephrosclerosis. It is generally accepted that, in benign nephrosclerosis, increased accumulation of extracellular matrix in the glomeruli results in glomerulosclerosis. Little is known, however, about the possible role of the extracellular matrix in the tubulointerstitial damage in benign nephrosclerosis. In this study, the possible roles of type IV basement-membrane collagen and type III interstitial collagen in tubulointerstitial damage caused by hypertens

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4

Hughson, M. D., V. G. Puelles, W. E. Hoy, R. N. Douglas-Denton, S. A. Mott, and J. F. Bertram. "Hypertension, glomerular hypertrophy and nephrosclerosis: the effect of race." Nephrology Dialysis Transplantation 29, no. 7 (2013): 1399–409. http://dx.doi.org/10.1093/ndt/gft480.

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5

Krishnan, R., T. P. Naushad, and N. Biju. "HYPERURICEMIA - A MARKER OF HYPERTENSIVE NEPHROSCLEROSIS IN ESSENTIAL HYPERTENSION?" Journal of Hypertension 22, Suppl. 2 (2004): S360. http://dx.doi.org/10.1097/00004872-200406002-01260.

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6

Ruilope, Luis M., Jos?? M. Alcazar, Eduardo Hernandez, et al. "177 Metabolic alterations accompanying essential hypertension are associated with nephrosclerosis." Journal of Hypertension 11, no. 5 (1993): S475. http://dx.doi.org/10.1097/00004872-199312050-00346.

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7

Pan, Xiaoqing, Xuemei Geng, Yong Liu, et al. "Transfer RNA Fragments in the Kidney in Hypertension." Hypertension 77, no. 5 (2021): 1627–37. http://dx.doi.org/10.1161/hypertensionaha.121.16994.

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Small noncoding RNAs (sncRNAs) are important regulators of gene expression. In contrast with well-studied microRNAs, transfer RNA-derived RNA fragments (tRFs) are a new class of sncRNAs that has not been studied in hypertension. This study aims to characterize renal tRFs and identify dysregulation and potential role of renal tRFs in hypertension. We analyzed sncRNA-sequencing and mRNA-sequencing data from the kidneys of Dahl salt-sensitive rats and sncRNA-sequencing data from kidney biopsy specimens from hypertensive nephrosclerosis patients. Over 300 tRFs were identified in the rat renal oute

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8

Muta, Kumiko, Yoko Obata, Satoru Oka, et al. "Curcumin ameliorates nephrosclerosis via suppression of histone acetylation independent of hypertension." Nephrology Dialysis Transplantation 31, no. 10 (2016): 1615–23. http://dx.doi.org/10.1093/ndt/gfw036.

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9

Wenzel, Ulrich O., Marlies Bode, Jörg Köhl, and Heimo Ehmke. "A pathogenic role of complement in arterial hypertension and hypertensive end organ damage." American Journal of Physiology-Heart and Circulatory Physiology 312, no. 3 (2017): H349—H354. http://dx.doi.org/10.1152/ajpheart.00759.2016.

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The self-amplifying cascade of messenger and effector molecules of the complement system serves as a powerful danger-sensing system that protects the host from a hostile microbial environment, while maintaining proper tissue and organ function through effective clearance of altered or dying cells. As an important effector arm of innate immunity, it also plays important roles in the regulation of adaptive immunity. Innate and adaptive immune responses have been identified as crucial players in the pathogenesis of arterial hypertension and hypertensive end organ damage. In line with this view, c

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10

Bidani, A. K., K. A. Griffin, W. Plott, and M. M. Schwartz. "Renal ablation acutely transforms 'benign' hypertension to 'malignant' nephrosclerosis in hypertensive rats." Hypertension 24, no. 3 (1994): 309–16. http://dx.doi.org/10.1161/01.hyp.24.3.309.

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11

Ono, Yuko, Hidehiko Ono, and Edward D. Frohlich. "Hydrochlorothiazide exacerbates nitric oxide-blockade nephrosclerosis with glomerular hypertension in spontaneously hypertensive rats." Journal of Hypertension 14, no. 7 (1996): 823–28. http://dx.doi.org/10.1097/00004872-199607000-00004.

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12

Forslund, Terje, Arvo Koistinen, Jorma Anttinen, Bodo Wagner, and Marja Miettinen. "Forty Years Abuse of Baking Soda, Rhabdomyolysis, Glomerulonephritis, Hypertension Leading to Renal Failure: A Case Report." Clinical Medicine: Case Reports 1 (January 2008): CCRep.S888. http://dx.doi.org/10.4137/ccrep.s888.

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We present a patient who had ingested sodium bicarbonate for treatment of alcoholic dyspepsia during forty years at increasing doses. During the last year he had used more than 50 grams daily. He presented with metabolic alkalosis, epileptic convulsions, subdural hematoma, hypertension and rhabdomyolysis with end stage renal failure, for which he had to be given regular intermittent hemodialysis treatment. Untreated hypertension and glomerulonephritis was probably present prior to all these acute incidents. Examination of the kidney biopsy revealed mesangial proliferative glomerulonephritis an

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13

Honma, Fumika, Yoshihide Fujigaki, Yoshikazu Nemoto, et al. "A Case of Rheumatoid Arthritis Presenting with Renal Thrombotic Microangiopathy Probably due to a Combination of Chronic Tacrolimus Arteriolopathy and Severe Hypertension." Case Reports in Nephrology 2019 (March 6, 2019): 1–7. http://dx.doi.org/10.1155/2019/3923190.

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A 51-year-old woman with rheumatoid arthritis presented with mild hypertension 20 months after tacrolimus treatment and developing proteinuria 24 months after the treatment. Tacrolimus was discontinued 27 months after the treatment, followed by heavy proteinuria, accelerated hypertension, and deteriorating renal function without ocular fundus lesions as a clinical sign of malignant hypertension. Renal biopsy revealed malignant nephrosclerosis characterized by subacute and chronic thrombotic microangiopathy (TMA), involving small arteries, arterioles, and glomeruli. Focal segmental glomeruloscl

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14

Sagliker, Y., Y. Ergun, H. Sabit Sagliker та ін. "[PP.07.10] PRIMAR HYPERTENSION. EARLY NEPHROSCLEROSIS BEGINS FIRST WITHIN THE LEFT KIDNEY. ERGUNʼS SIGN". Journal of Hypertension 35 (вересень 2017): e139. http://dx.doi.org/10.1097/01.hjh.0000523367.00293.bc.

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15

Marín, Rafael, Manuel Gorostidi, Francisco Fernández-Vega, and Rafael Álvarez-Navascués. "Systemic and glomerular hypertension and progression of chronic renal disease: The dilemma of nephrosclerosis." Kidney International 68 (December 2005): S52—S56. http://dx.doi.org/10.1111/j.1523-1755.2005.09910.x.

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16

Sanders, L. R. "Exercise-induced acute renal failure associated with ibuprofen, hydrochlorothiazide, and triamterene." Journal of the American Society of Nephrology 5, no. 12 (1995): 2020–23. http://dx.doi.org/10.1681/asn.v5122020.

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Nonsteroidal anti-inflammatory drugs predispose to acute renal failure in conditions associated with decreased RBF. Such conditions include advanced age, hypertension, chronic renal insufficiency, diuretic use, and any condition decreasing effective circulating volume. Strenuous exercise also causes marked reductions in RBF. The patient discussed developed severe acute renal failure after strenuous exercise and therapeutic doses of ibuprofen and hydrochlorothiazide-triamterene. Urinalysis showed a nephritic sediment with red blood cell casts. Renal biopsy showed acute tubular necrosis and arte

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17

Zingaro, Laura, Cristiana Catena, Sergio De Marchi, and Leonardo Sechi. "Increased Fibrinogen Levels and Hemostatic Abnormalities in Patients with Arteriolar Nephrosclerosis: Association with Cardiovascular Events." Thrombosis and Haemostasis 84, no. 10 (2000): 565–70. http://dx.doi.org/10.1055/s-0037-1614068.

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SummaryIncreased plasma fibrinogen levels and hemostatic abnormalities suggestive of a prothrombotic state are present in patients with endstage renal failure and could contribute to increased cardiovascular morbidity in these patients. We investigated the relationship between abnormalities of the hemostatic system and the degree of renal failure and whether these abnormalities are associated with increased prevalence of cardiovascular events in patients with arteriolar nephrosclerosis. In 425 patients recruited at a hypertension clinic we assessed the renal function by creatinine clearance, u

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18

Wenzel, U. O., G. Troschau, W. Schoeppe, U. Helmchen, and G. Schwietzer. "Adverse effect of the calcium channel blocker nitrendipine on nephrosclerosis in rats with renovascular hypertension." Hypertension 20, no. 2 (1992): 233–41. http://dx.doi.org/10.1161/01.hyp.20.2.233.

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19

Ni, A., T. A. Shumatova, V. N. Luchaninova, E. V. Grivkova, and O. V. Semeshina. "A CASE OF LEFT-SIDED OCCLUSION OF THE RENAL ARTERY IN A CHILD WITH A GENETIC FORM OF THROMBOPHILIA." Nephrology (Saint-Petersburg) 21, no. 1 (2017): 95–100. http://dx.doi.org/10.24884/1561-6274-2017-21-1-95-100.

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Recently has greatly improved diagnosis of hereditary thrombophilia. Unlike other forms of methylene tetrahydro folate reduktase gene mutation (MTHFR) that are characteristic of both venous and arterial thrombosis. In the literature described isolated cases of thrombosis of renal vessels in adults. The authors describe their own observation of a child with a congenital heart defect, who inherited thrombophilia manifested by the development of left-sided occlusion of the renal artery, resulting in severe renovascular hypertension and nephrosclerosis of left kidney. The girl on molecular genetic

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20

Yu, H., D. W. Bowden, B. J. Spray, S. S. Rich, and B. I. Freedman. "Linkage analysis between loci in the renin-angiotensin axis and end-stage renal disease in African Americans." Journal of the American Society of Nephrology 7, no. 12 (1996): 2559–64. http://dx.doi.org/10.1681/asn.v7122559.

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The factors that initiate chronic renal failure in patients with hypertension, diabetes mellitus, and chronic glomerular disease are largely unknown. The likely genetic contribution to ESRD, particularly in African Americans, suggests that linkage analysis may be useful to evaluate the role of candidate genes in the pathogenesis of chronic renal failure. The renin-angiotensin-aldosterone (RAA) axis has been intensively evaluated for its contribution to cardiovascular disease and nephropathy. This study tested for linkage between candidate genes in the RAA axis and chronic renal failure, using

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21

Alchinbayev, M., N. Kadyrbekov, and A. Baitenizova. "UP-2.021: Ultrasonic Dopplerography in Diagnostics of Chronic Pyelonephritis Complicated by Nephrogenic Hypertension and Factors of Nephrosclerosis." Urology 74, no. 4 (2009): S239. http://dx.doi.org/10.1016/j.urology.2009.07.240.

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22

Fejes, I., A. Balog, D. Bajcsi, et al. "PREVALENCE OF HYPERTENSIVE NEPHROSCLEROSIS BY A 10-YEAR LONG KIDNEY BIOPSY DATABASE OF SZEGED NEPHROLOGY-HYPERTENSION CENTER." Journal of Hypertension 37 (July 2019): e260-e261. http://dx.doi.org/10.1097/01.hjh.0000573328.51789.f0.

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23

Carriazo, Sol, Maria Vanessa Perez-Gomez, and Alberto Ortiz. "Hypertensive nephropathy: a major roadblock hindering the advance of precision nephrology." Clinical Kidney Journal 13, no. 4 (2020): 504–9. http://dx.doi.org/10.1093/ckj/sfaa162.

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Abstract In the 2017 Annual Report of the ERA-EDTA Registry, hypertension continues to be the second or third most common cause of renal replacement therapy (RRT) in Europe, tied with glomerulonephritis. There is, however, one little issue: hypertension-induced end-stage renal disease (ESRD) might not exist at all as currently understood, that is, as hypertensive nephrosclerosis. In this regard, the incidence of RRT due to hypertensive nephropathy is related to the incidence of other causes of ESRD but not to the burden of hypertension per country. The current definition of hypertensive nephro

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24

Hartner, Andrea, Nada Cordasic, Bernd Klanke, Michael Wittmann, Roland Veelken, and Karl F. Hilgers. "Renal injury in streptozotocin-diabetic Ren2-transgenic rats is mainly dependent on hypertension, not on diabetes." American Journal of Physiology-Renal Physiology 292, no. 2 (2007): F820—F827. http://dx.doi.org/10.1152/ajprenal.00088.2006.

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Induction of streptozotocin (STZ) diabetes in hypertensive rats transgenic for the mouse ren-2 gene (TGR) has been described as a model of progressive diabetic nephropathy. We investigated the long-term course of STZ diabetes in TGR and appropriate Sprague-Dawley control rats (SD) and tested the role of angiotensin-dependent hypertension by treating rats with the angiotensin II type 1 receptor blocker losartan (1 mg·kg−1·day−1) via osmotic minipumps. Five weeks after STZ injection, diabetes developed in TGR and SD. Urinary albumin excretion was increased by diabetes and, to a much higher degre

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25

Randall, Otelio, John Kwagyan, Tamrat Retta, et al. "Effect of Intensive Blood Pressure Control on Cardiovascular Remodeling in Hypertensive Patients with Nephrosclerosis." International Journal of Nephrology 2013 (2013): 1–8. http://dx.doi.org/10.1155/2013/120167.

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Pulse pressure (PP), a marker of arterial system properties, has been linked to cardiovascular (CV) complications. We examined (a) association between unit changes of PP and (i) composite CV outcomes and (ii) development of left-ventricular hypertrophy (LVH) and (b) effect of mean arterial pressure (MAP) control on rate of change in PP. We studied 1094 nondiabetics with nephrosclerosis in the African American Study of Kidney Disease and Hypertension. Subjects were randomly assigned to usual MAP goal (102–107 mmHg) or a lower MAP goal (≤92 mmHg) and randomized to beta-blocker, angiotensin conve

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26

Larivière, Richard, and Marcel Lebel. "Endothelin-1 in chronic renal failure and hypertension." Canadian Journal of Physiology and Pharmacology 81, no. 6 (2003): 607–21. http://dx.doi.org/10.1139/y03-012.

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Investigation into the role of endothelin-1 (ET-1) in renal function has revealed two major direct actions leading to the control of extracellular volume and blood pressure. These are the regulation of renal hemodynamics and glomerular filtration rate and the modulation of sodium and water excretion. In the rat remnant kidney model of chronic renal failure, ET-1 production is increased in blood vessels and renal tissues. These changes are related to an increase in preproET-1 expression and correlate with the rise in blood pressure, the development of cardiovascular hypertrophy, and the degree

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27

Seccia, Teresa, Brasilina Caroccia, Maria Piazza, and Gian Paolo Rossi. "The Key Role of Epithelial to Mesenchymal Transition (EMT) in Hypertensive Kidney Disease." International Journal of Molecular Sciences 20, no. 14 (2019): 3567. http://dx.doi.org/10.3390/ijms20143567.

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Accumulating evidence indicates that epithelial-to-mesenchymal transition (EMT), originally described as a key process for organ development and metastasis budding in cancer, plays a key role in the development of renal fibrosis in several diseases, including hypertensive nephroangiosclerosis. We herein reviewed the concept of EMT and its role in renal diseases, with particular focus on hypertensive kidney disease, the second leading cause of end-stage renal disease after diabetes mellitus. After discussing the pathophysiology of hypertensive nephropathy, the ‘classic’ view of hypertensive nep

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Denic, Aleksandar, Hisham Elsherbiny, Aidan F. Mullan, et al. "Larger Nephron Size and Nephrosclerosis Predict Progressive CKD and Mortality after Radical Nephrectomy for Tumor and Independent of Kidney Function." Journal of the American Society of Nephrology 31, no. 11 (2020): 2642–52. http://dx.doi.org/10.1681/asn.2020040449.

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BackgroundNephron hypertrophy and nephrosclerosis may be important determinants of CKD and mortality. However, studies of outcomes associated with these microstructural features have been limited to small tissue specimens from patients selected for either good kidney health or known kidney disease.MethodsTo determine whether microstructural features are predictive of progressive CKD and mortality outcomes, we studied patients who underwent a radical nephrectomy for a tumor. Large wedge sections of renal parenchyma distal to the tumor were stained and scanned into high-resolution images; we ann

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Liu, Yong, Kristie Usa, Feng Wang, et al. "MicroRNA-214-3p in the Kidney Contributes to the Development of Hypertension." Journal of the American Society of Nephrology 29, no. 10 (2018): 2518–28. http://dx.doi.org/10.1681/asn.2018020117.

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BackgroundIn spite of extensive study, the mechanisms for salt sensitivity of BP in humans and rodent models remain poorly understood. Several microRNAs (miRNAs) have been associated with hypertension, but few have been shown to contribute to its development.MethodsWe examined miRNA expression profiles in human kidney biopsy samples and rat models using small RNA deep sequencing. To inhibit an miRNA specifically in the kidney in conscious, freely moving rats, we placed indwelling catheters to allow both renal interstitial administration of a specific anti-miR and measurement of BP. A rat with

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Mai, Monika, H. Geiger, J. D??mmrich, A. Singer, Karl F. Hilgers, and Freidrich C. Luft. "131 Effect of extracellular matrix and mononuclear cells in the pathogenesis of hypertensive nephrosclerosis in two-kidney, one clip hypertension." Journal of Hypertension 11, no. 5 (1993): S454. http://dx.doi.org/10.1097/00004872-199312050-00300.

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31

Douglas, Janice G., and Lawrence Agodoa. "ACE inhibition is effective and renoprotective in hypertensive nephrosclerosis: The African American Study of Kidney Disease and Hypertension (AASK) trial." Kidney International 63 (February 2003): S74—S76. http://dx.doi.org/10.1046/j.1523-1755.63.s83.15.x.

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32

Stanchev, Stancho S., Alexandar A. Iliev, Lina G. Malinova, Boycho V. Landzhov, Georgi N. Kotov, and Dimka V. Hinova-Palova. "Light Microscopic Study of Renal Morphological Alterations in Spontaneously Hypertensive Rats." Journal of Biomedical and Clinical Research 10, no. 1 (2017): 18–24. http://dx.doi.org/10.1515/jbcr-2017-0003.

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SummaryThe impact of hypertension on the kidney is associated with a number of morphological changes, which gradually lead to development of end-stage kidney disease. The aim of the present study was to trace the postnatal histological changes in the morphology of nephrons and renal interstitium in spontaneously hypertensive rats. In this study, we described and compare alterations in renal histology as a consequence of hypertension in two age groups of spontaneously hypertensive rats, aged 2 and 6 months (n=3; per age group). The description of the alterations in renal morphology was made by

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Joshi, Keshab Raj, Ashish Gautam, Dipendra Raj Pandeya, and Keshab Poudel. "Serum Creatinine and Urine Microalbumin Level in Hypertensive and Non hypertensive Patients." Medical Journal of Shree Birendra Hospital 12, no. 2 (2015): 27–30. http://dx.doi.org/10.3126/mjsbh.v12i2.12923.

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Introduction: Hypertension is one of the most common cardiovascular disorders, more likely to accelerateatherosclerosis causing cardiovascular complications and benign arteriolar nephrosclerosis for an extendedperiod of time may manifest as a mild to moderate elevation of serum creatinine and/or microalbuminuria.Methods: The present study was carried out on total 100 subjects. Which were divided into two groups. Firstgroup of experimental group consist of 50 subjects with known Hypertensive Subjects. Another group is controlgroup consist of 50 Non-Hypertensive Subjects with no present and past

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34

Ying, Wei-Zhong, та Paul W. Sanders. "The interrelationship between TGF-β1 and nitric oxide is altered in salt-sensitive hypertension". American Journal of Physiology-Renal Physiology 285, № 5 (2003): F902—F908. http://dx.doi.org/10.1152/ajprenal.00177.2003.

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The study of salt-sensitive hypertension has been facilitated by development of genetic models, especially the Dahl/Rapp salt-sensitive (S) rat. S rats rapidly become hypertensive after initiation of a diet containing 8.0% NaCl and subsequently develop arteriolonephrosclerosis and renal failure, whereas the salt-resistant (R) strain remains normotensive on the same diet. The purpose of the present study was to use these strains to demonstrate the interactions between transforming growth factor-β1 (TGF-β1) and nitric oxide (NO). Young, male S and R rats were fed for 4 days diets that contained

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35

Menendez-Castro, Carlos, Nada Cordasic, Thomas Dambietz, et al. "Correlations Between Interleukin-11 Expression and Hypertensive Kidney Injury in a Rat Model of Renovascular Hypertension." American Journal of Hypertension 33, no. 4 (2019): 331–40. http://dx.doi.org/10.1093/ajh/hpz194.

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Abstract BACKGROUND Interleukin-11 (IL-11) is a pleiotropic cytokine of the interleukin-6 family. Recent studies revealed its crucial role in the development of cardiovascular fibrosis. In this study we examined IL-11 expression levels in the heart and the kidney exposed to high blood pressure in renovascular hypertensive rats and their correlations to fibrotic markers and kidney injury. METHODS Two-kidney, one-clip renovascular hypertension (2K1C) was induced in rats. IL-11 expression was measured by real-time polymerase chain reaction in the left ventricle and the right kidney. The correlati

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Uramatsu, Tadashi, Tomoya Nishino, Yoko Obata, et al. "Involvement of Apoptosis Inhibitor of Macrophages in a Rat Hypertension Model with Nephrosclerosis: Possible Mechanisms of Action of Olmesartan and Azelnidipine." Biological and Pharmaceutical Bulletin 36, no. 8 (2013): 1271–77. http://dx.doi.org/10.1248/bpb.b12-00965.

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Cheng, Yuan, Dandan Wang, Feng Wang, et al. "Endogenous miR-204 Protects the Kidney against Chronic Injury in Hypertension and Diabetes." Journal of the American Society of Nephrology 31, no. 7 (2020): 1539–54. http://dx.doi.org/10.1681/asn.2019101100.

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BackgroundAberrant microRNA (miRNA) expression affects biologic processes and downstream genes that are crucial to CKD initiation or progression. The miRNA miR-204-5p is highly expressed in the kidney but whether miR-204-5p plays any role in the development of chronic renal injury is unknown.MethodsWe used real-time PCR to determine levels of miR-204 in human kidney biopsies and animal models. We generated Mir204 knockout mice and used locked nucleic acid–modified anti-miR to knock down miR-204-5p in mice and rats. We used a number of physiologic, histologic, and molecular techniques to analyz

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Barkate, Hanmant, Jatin Kothari, Himanshu Patel, A. V. Ingale, and Salman Motlekar. "Darbepoetin alfa: review in the management of anemia in patients with chronic kidney disease." International Journal of Basic & Clinical Pharmacology 6, no. 3 (2017): 474. http://dx.doi.org/10.18203/2319-2003.ijbcp20170808.

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Chronic kidney disease (CKD) is a significant clinical problem across the world including India. The SEEK (Screening and Early Evaluation of Kidney Disease) study from India reported the prevalence of CKD as 17.2%. Diabetic nephropathy, undetermined etiology, chronic glomerulonephritis and hypertensive nephrosclerosis are the common causes of CKD in India. Rising rates of diabetes and hypertension, late presentation of patients to nephrologists and limited number of nephrologists in India adds to the concerns related to management of CKD. Considering the pathophysiology of CKD, anemia is almos

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Toto, Robert D., Tom Greene, Lee A. Hebert, et al. "Relationship Between Body Mass Index and Proteinuria in Hypertensive Nephrosclerosis: Results From the African American Study of Kidney Disease and Hypertension (AASK) Cohort." American Journal of Kidney Diseases 56, no. 5 (2010): 896–906. http://dx.doi.org/10.1053/j.ajkd.2010.05.016.

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40

Sombolos, Kostas, Peter McNamee, Ahmed Mitwalli, Sol Rabinovich, and Dimitrios G. Oreopoulos. "Autopsy Findings in Patients Treated by Continuous Ambulatory Peritoneal Dialysis (CAPD)." Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 6, no. 3 (1986): 130–35. http://dx.doi.org/10.1177/089686088600600305.

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From October 1977 to October 1985, our pathology department did autopsies on 19 patients (14 men, five women) treated by CAPD for four to 55 (mean 29.3) months. Their mean age was 60.2 (range 28–79) years and the primary renal diseases were diabetes mellitus (eight), nephrosclerosis (five), polycystic kidneys (three), chronic glomerulonephritis (one) and chronic renal failure associated with sarcoidosis and congestive cardiomyopathy in two. During the same period, the authors selected as controls 18 autopsied patients (14 men, four women), who had not had chronic renal failure, and these were

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Stier, Charles T., Praveen N. Chander, Louis Rosenfeld, and C. Andrew Powers. "Estrogen promotes microvascular pathology in female stroke-prone spontaneously hypertensive rats." American Journal of Physiology-Endocrinology and Metabolism 285, no. 1 (2003): E232—E239. http://dx.doi.org/10.1152/ajpendo.00029.2003.

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Estrogen produces both beneficial and adverse effects on cardiovascular health via mechanisms that remain unclear. Stroke-prone spontaneously hypertensive rats (SHRSP) maintained on Stroke-Prone Rodent Diet and 1% NaCl drinking water (starting at 8 wk of age) rapidly develop stroke and malignant nephrosclerosis that can be prevented, despite continued hypertension, by drugs targeting angiotensin II and aldosterone actions. This study evaluated estrogen's effects in the SHRSP model. Female SHRSP that were sham operated (SHAM), ovariectomized (OVX) at 4 wk of age, or OVX and treated with estradi

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Zimina, L. N., G. A. Berdnikov, S. I. Rey, and S. Yu Kambarov. "Morphological Aspects of Acute Renal Injury in Cardiac Surgery." Russian Sklifosovsky Journal "Emergency Medical Care" 9, no. 4 (2021): 539–44. http://dx.doi.org/10.23934/2223-9022-2020-9-4-539-544.

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Summary. The use of endoscopic transsphenoidal access is an effective and safe method for the surgical treatment of pituitary adenomas (PA). In endoscopic transsphenoidal surgeries, there is a need to control intracranial pressure (ICP) for reposition and expansion of the tumor capsule. Currently, the main method for reducing ICP in transsphenoidal surgery is installation of an external lumbar drainage, which is associated with a number of complications.Aim of study. To improve the results of surgical treatment of patients with arterial hypertension using hypertonic saline solution.Material an

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Denic, Aleksandar, Jerry Mathew, Venkata V. Nagineni, et al. "Clinical and Pathology Findings Associate Consistently with Larger Glomerular Volume." Journal of the American Society of Nephrology 29, no. 7 (2018): 1960–69. http://dx.doi.org/10.1681/asn.2017121305.

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Background Glomerular volume increases when demand exceeds nephron supply, which may lead to glomerulosclerosis. It is unclear if determinants of glomerular volume are consistent between populations that differ by severity of comorbidities.Methods We studied kidney biopsy specimens from living kidney donors (n=2453) and patients who underwent radical nephrectomy for a renal tumor (n=780). We scanned specimen sections into high-resolution digital images, manually traced glomerular profiles, and calculated mean glomerular volumes using the Weibel–Gomez stereologic formula (separately for nonscle

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Helve, Jaakko, Mikko Haapio, Per-Henrik Groop, and Patrik Finne. "Primary kidney disease modifies the effect of comorbidities on kidney replacement therapy patients’ survival." PLOS ONE 16, no. 8 (2021): e0256522. http://dx.doi.org/10.1371/journal.pone.0256522.

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Background Comorbidities are associated with increased mortality among patients receiving long-term kidney replacement therapy (KRT). However, it is not known whether primary kidney disease modifies the effect of comorbidities on KRT patients’ survival. Methods An incident cohort of all patients (n = 8696) entering chronic KRT in Finland in 2000–2017 was followed until death or end of 2017. All data were obtained from the Finnish Registry for Kidney Diseases. Information on comorbidities (coronary artery disease, peripheral vascular disease, left ventricular hypertrophy, heart failure, cerebro

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Smith, Andrew, Vadim Iablokov, Mariafrancesca Mazza, et al. "Detecting Proteomic Indicators to Distinguish Diabetic Nephropathy from Hypertensive Nephrosclerosis by Integrating Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging with High-Mass Accuracy Mass Spectrometry." Kidney and Blood Pressure Research 45, no. 2 (2020): 233–48. http://dx.doi.org/10.1159/000505187.

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Introduction: Diabetic nephropathy (DN) and hypertensive nephrosclerosis (HN) represent the most common causes of chronic kidney disease (CKD) and many patients progress to end-stage renal disease. Patients are treated primarily through the management of cardiovascular risk factors and hypertension; however patients with HN have a more favorable outcome. A noninvasive clinical approach to separate these two entities, especially in hypertensive patients who also have diabetes, would allow for targeted treatment and more appropriate resource allocation to those patients at the highest risk of

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Gazizova, G. R. "The role of pro-inflammatory cytokines in diabetic nephropathy in pregnant women with type 1 diabetes mellitus." Kazan medical journal 94, no. 1 (2013): 105–10. http://dx.doi.org/10.17816/kmj1781.

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Diabetic nephropathy is one of the most frequent and unfavorable complications of pregnancy in terms of prognosis in patients with diabetes mellitus. The combination of pregnancy and uncompensated diabetes with such complications as diabetic nephropathy, diabetic retinopathy, diabetic neuropathy, leads to overproduction of pro-inflammatory cytokines, thromboses and ischemic necroses of the fetoplacental tissues, and low blood level of immunosuppressive cytokines increases the severity of the disease. This mechanism may be one of the reasons of the spontaneous abortion and pregnancy loss in ear

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Toto, R. D., K. A. Kirk, J. Coresh, et al. "Evaluation of serum creatinine for estimating glomerular filtration rate in African Americans with hypertensive nephrosclerosis: results from the African-American Study of Kidney Disease and Hypertension (AASK) Pilot Study." Journal of the American Society of Nephrology 8, no. 2 (1997): 279–87. http://dx.doi.org/10.1681/asn.v82279.

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Measurement of GFR is considered the standard for estimating renal function. However, standardized accurate GFR methodology is expensive and cumbersome; therefore, estimates of GFR based on serum creatinine concentration have been employed. The purpose of the study presented here was to assess the accuracy and precision of using serum creatinine measurements to estimate GFR in the screen cohort of The African-American Study of Kidney Disease and Hypertension (AASK) Pilot Study. GFR was estimated by four methods: 100/serum creatinine, Cockcroft-Gault equation, creatinine clearance from 24-h uri

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Khakurel, Sudha, Rajendra Kumar Agrawal, and Rajani Hada. "Pattern of End Stage Renal Disease in a Tertiary Care Center." Journal of Nepal Medical Association 48, no. 174 (2009): 126–30. http://dx.doi.org/10.31729/jnma.227.

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Introduction: End Stage renal disease (ESRD) is a major public health problem across the world and it is rising. The incidence prevalence and causes of ESRD is not known in Nepal. With a population of 27 million people the estimated incidence of ESRD is around 2700/year if we take 100/million population at par with India and Pakistan. However majority of patients do not reach hospitals with dialysis facilities. The aim of the present study was to analyze the clinico-epidemiological profile of ESRD in the Nepalese context. Methods: A retrospective, cross sectional study was conducted on newly d

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Argiolu, Francesca, Maria Adele Sanna, Antonella Bartoli, et al. "Haematopoietic Stem Cell Transplantation in Thalassaemic Patient with Renal Failure on Hemodialysis." Blood 112, no. 11 (2008): 4338. http://dx.doi.org/10.1182/blood.v112.11.4338.4338.

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Abstract Until now few patients with renal failure on hemodialysis have undergone haematopoietic stem-cell transplantation (HSCT), and none with thalassaemia. Case report. Patient of 45 years, UPN 168, with β Thalassaemia major, genetic compound β0 39 C--&gt;T/β0 6-A, non transfusible due to red blood cell immunization (positive DAT, Hb 5–7 g/dl), under hemodialytic treatment for three years for bilateral focal nephrosclerosis. He suffered from cardiopathy (atrial thrombosis, pulmonary hypertension, atrial and ventricular dilatation), hypothyroidism, hepatopathy (HCV positive with grade II

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Sathyan, Swaraj, Sunil George, and Poornima Vijayan. "Prevalence of anemia and cardiovascular diseases in chronic kidney disease patients: a single tertiary care centre study." International Journal of Advances in Medicine 4, no. 1 (2017): 247. http://dx.doi.org/10.18203/2349-3933.ijam20170120.

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Background: Chronic kidney disease (CKD) is recognized as a global health issue having high mortality and morbidity rates putting a substantial burden on global resources. CKD has become a recognised independent risk factor for several adverse health outcomes including cardiovascular disease (CVD). Anaemia is an anticipated consequence as renal function declines, and can develop at any stage of CKD. There is a strong association between anemia and cardiovascular complications in CKD patients and many studies have proven that anemia plays a key role in worsening CVD in CKD patients. The objecti

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